Vanja Dakic

Formação complementar

Idiomas

Áreas de atuação

Organização de eventos

Participação em eventos

Comissão julgadora das bancas

Foi orientado por

Produções bibliográficas

• DE VECCHI, RODRIGO ; DAKIC, VANJA ; MATTOS, GUILHERME ; RIGAUDEAU, ANNE-SOPHIE ; OLIVEIRA, VERONICA ; GARCIA, CRISTINA ; ALÉPÉE, NATHALIE ; COTOVIO, JOSÉ ; BOUEZ, CHARBEL . Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil. Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia , v. 6, p. 64, 2018.

• DAKIC, VANJA ; MINARDI NASCIMENTO, JULIANA ; COSTA SARTORE, RAFAELA ; MACIEL, RENATA DE MORAES ; DE ARAUJO, DRAULIO B. ; RIBEIRO, SIDARTA ; MARTINS-DE-SOUZA, DANIEL ; REHEN, STEVENS K. . Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT. Scientific Reports , v. 7, p. 12863 (2017), 2017.

• DAKIC, VANJA ; MACIEL, RENATA DE MORAES ; DRUMMOND, HANNAH ; NASCIMENTO, JULIANA M. ; TRINDADE, PABLO ; REHEN, STEVENS K. . Harmine stimulates proliferation of human neural progenitors. PeerJ , v. 4, p. e2727, 2016.

• KAISAREVIC, SONJA ; DAKIC, VANJA ; HRUBIK, JELENA ; GLISIC, BRANKA ; LÜBCKE-VON VAREL, URTE ; POGRMIC-MAJKIC, KRISTINA ; FA, SVETLANA ; TEODOROVIC, IVANA ; BRACK, WERNER ; KOVACEVIC, RADMILA . Differential expression of CYP1A1 and CYP1A2 genes in H4IIE rat hepatoma cells exposed to TCDD and PAHs. Environmental Toxicology and Pharmacology , v. 39, p. 358-368, 2015.

• FA, SVETLANA ; POGRMIC-MAJKIC, KRISTINA ; DAKIC, VANJA ; KAISAREVIC, SONJA ; HRUBIK, JELENA ; ANDRIC, NEBOJSA ; STOJILKOVIC, STANKO S. ; KOVACEVIC, RADMILA . Acute effects of hexabromocyclododecane on Leydig cell cyclic nucleotide signaling and steroidogenesis in vitro. Toxicology Letters , v. 218, p. 81-90, 2013.

• Dakic, Vanja ; POGRMIC-MAJKIC, KRISTINA ; KAISAREVIC, SONJA ; FA, SVETLANA ; GLISIC, BRANKA ; HRUBIK, JELENA ; KOVACEVIC, RADMILA . Atrazine effects on antioxidant status and xenobiotic metabolizing enzymes after oral administration in peripubertal male rat. Environmental Toxicology and Pharmacology , v. 34, p. 495-501, 2012.

• Teodorovic I. ; Kaisarevic S. ; Pogrmic-Majkic K. ; Planojevic I. ; Fa S. ; Dakic, Vanja ; Hrubik J. ; Gliisic B. ; Kovacevic R. . REP-LECOTOX: an example of FP 6 INCO project to strengthen ecotoxicological research in WBC (Western Balkan countries). Environmental Sciences Europe , v. 23:5, p. 1-5, 2011.

• Teodorovic I. ; Kaisarevic S. ; Planojevic I. ; Fa S. ; Dakic, Vanja ; Pogrmic-Majkic K. ; Hrubik J. ; Gliisic B. ; Kovacevic R. . Second REP-LECOTOX Workshop "Trends in Ecological Risk Assessment". Environmental Science and Pollution Research International , v. 23:6, p. 1-3, 2011.

• Dakic, Vanja ; David R. ; Williams T. ; Winter M. ; Chipman K. . Transcriptional responses in neonate and adult Daphnia magna in relation to relative susceptibility to genotoxicants. Aquatic Toxicology , v. 104, p. 192-204, 2011.

• POGRMIC-MAJKIC, K. ; FA, S. ; KOVACEVIC, R. ; DAKIC, V. ; KAISAREVIC, S. . Upregulation of Peripubertal Rat Leydig Cell Steroidogenesis Following 24 h In Vitro and In Vivo Exposure to Atrazine. Toxicological Sciences (Print) , v. 118, p. 52-60, 2010.

• POGRMIC, K. ; DAKIC, V. ; FA, S. ; KAISAREVIC, S. ; KOVACEVIC, R. . Atrazine Oral Exposure of Peripubertal Male Rats Downregulates Steroidogenesis Gene Expression in Leydig Cells. Toxicological Sciences (Print) , v. 111, p. 189-197, 2009.

• KOVACEVIC, R. ; TEODOROVIC, I. ; FA, S. ; POGRMIC, K. ; KAISAREVIC, S. ; VIRIJEVIC, S. ; DAKIC, V. ; PLANOJEVIC, I. . First REP-LECOTOX Workshopâecotoxicogenomics: the challenge of integrating genomics/proteomics/metabolomics into aquatic and terrestrial ecotoxicology. Environmetal Science and Pollution Research International (Internet) , v. 16, p. 130-131, 2009.

• Dakic, V. ; Paulsen, Bruna, S ; Maciel, Renata, M. ; Madeiro, Rodrigo, C. ; Ramalho, Bia, ; Rehen, Stevens, K. . Pluripotent Stem Cells as Tools for Studying the Effects of Psychedelic Substances in Human Neurons. In: Psychedelic Science 2013, 2013, Oakland. Psychedelic Science 2013, 2013.

• Fa S. ; Dakic, Vanja ; Pogrmic-Majkic K. ; Hrubik J. ; Kaisarevic S. ; Kovacevic R. . Transient stimulatory action of atrazine on cAMP signaling pathway in Leydig cells. In: FEBS Workshop on Spatiotemporal Dynamics of Cell Signaling, 2010, Oslo. FEBS Workshop on Spatiotemporal Dynamics of Cell Signaling. Oslo. v. 1. p. 14-14.

• FA, S ; Dakic, Vanja ; POGRMIC-MAJKIC, K ; Hrubik J. ; KAISAREVIC, S ; KOVACEVIC, R . Toxic effects of HBCDD upon Leydig cell steroidogenesis ? possible role of mitochondria?. In: Mitochondrial phisiology; The many functions of the organism in our cells, 2010, Obergurgl. Toxic effects of HBCDD upon Leydig cell steroidogenesis ? possible role of mitochondria?. Obergurgl, 2010. v. 1. p. 71-71.

• Kaisarevic S. ; Lübcke-von Varel U. ; Orcic D. ; Streck G. ; Schulze T. ; Tubic A. ; Dakic, Vanja ; Pogrmic-Majkic K. ; Teodorovic I. ; Brack W. ; Kovacevic R. . EFFECT-DIRECTED ANALYSIS OF CONTAMINATED SEDIMENT FROM THE WASTEWATER CANAL IN PANCEVO INDUSTRIAL AREA, SERBIA.. In: Characterisation of hazardous chemical contamination - from environmental chemistry and toxicology to risk assessment (NATO SfP 982590 project workshop), 2010, Dubrovnik. Characterisation of hazardous chemical contamination - from environmental chemistry and toxicology to risk assessment (NATO SfP 982590 project workshop). Dubrovnik, 2010. v. 1. p. 25-25.

• Fa S. ; Dakic, Vanja ; Pogrmic-Majkic K. ; Hrubik J. ; Kovacevic R. . HBCDD INDUCES TOXIC EFFECT ON STEROIDOGENIC POTENTIAL OF PERIPUBERTAL RAT LEYDIG CELLS. In: 10th CONGRESS OF TOXICOLOGISTS OF SERBIA, 2010, Palic. 10th CONGRESS OF TOXICOLOGISTS OF SERBIA. Palic, 2010. v. 1. p. 18-18.

• Kaisarevic S. ; Tubic A. ; Schulze T. ; Dakic, Vanja ; Lübcke-von Varel U. ; Brack W. . EFFECT-DIRECTED ANALYSIS OF SELECTED ORGANIC FRACTIONS OF SEDIMENT FROM THE WASTEWATER CANAL IN PANCEVO INDUSTRIAL AREA, SERBIA. In: 10th CONGRESS OF TOXICOLOGISTS OF SERBIA, 2010, Palic. 10th CONGRESS OF TOXICOLOGISTS OF SERBIA. Palic, 2010. v. 1. p. 125.

• Dakic, Vanja ; Pogrmic-Majkic K. ; Fa S. ; Kaisarevic S. ; Hrubik J. ; Kovacevic R. . In vivo transient stimulatory effect of atrazine on rat testicular steroidogenesis. In: International Symposium ?One hundred years of Ivan Djajas Belgrade School of Physiology, 2010, Belgrade. International Symposium ?One hundred years of Ivan Djajas Belgrade School of Physiology. Belgrade, 2010. v. 1. p. 87-87.

• Fa S. ; Dakic, Vanja ; Pogrmic-Majkic K. ; Hrubik J. ; Kovacevic R. . Toxic effects of HBCDD upon Leydig cell steroidogenesis in peripubertal rats. In: International Symposium ?One hundred years of Ivan Djajas Belgrade School of Physiology, 2010, Belgrade. International Symposium ?One hundred years of Ivan Djajas Belgrade School of Physiology. Belgrade, 2010. p. 89-89.

• Pogrmic-Majkic K. ; Dakic, Vanja ; Fa S. ; Kaisarevic S. ; Kovacevic R. . Atrazine-induced modulation of peripubertal rat Leydig cell steroidogenesis. In: Gordon Reasearch Conference: Environmental Endocrine Disruptors, 2010, Les Diablerets. Gordon Reasearch Conference: Environmental Endocrine Disruptors. Les Diablerets, 2010. p. 26-26.

• Kaisarevic S. ; Tubic A. ; Schulze T. ; Streck G. ; Lübcke-von Varel U. ; Sperreuter A. ; Dakic, Vanja ; Pogrmic-Majkic K. ; Teodorovic I. ; Brack W. ; Kovacevic R. . Contaminated sediment from industrial area in Serbia: Further steps in effect-directed analysis. In: Setac Europe: 20th annual Meeting, Science and technology for environmental protection, 2010, Seville. Setac Europe: 20th annual Meeting, Science and technology for environmental protection. Seville, 2010. p. 137-138.

• Kovacevic R. ; Teodorovic I. ; Kaisarevic S. ; Fa S. ; Pogrmic-Majkic K. ; Planojevic I. ; Dakic, Vanja . EC FP6 REP-LECOTOX Project. EC FP ? facilitated success story how LECOTOX became visible on scientific map of Europe. In: MODELKEY Final Conference ? How to assess the impact of key pollutants in aquatic ecosystems, 2009, Leipzig. MODELKEY Final Conference ? How to assess the impact of key pollutants in aquatic ecosystems. Leipzig, 2009. p. 62-62.

• David R. ; Dakic, Vanja ; Williams T. ; Winter M. ; Chipman K. . Identification of Molecular Level Idicators of Genotoxicant Activation and Exposure in Daphnia Magna. In: 15th International Symposium on Pollutant Responses in Marine Organisms, 2009, Bordeaux. 15th International Symposium on Pollutant Responses in Marine Organisms. Bordeaux, 2009. p. 391-391.

• Pogrmic-Majkic K. ; Fa S. ; Kaisarevic S. ; Dakic, Vanja ; Kovacevic R. . Atrazine Oral Exposure Inhibits Expression of Genes Responsible for Steroidogenesis in Peripubertal Rat Leydig Cells. In: 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology, 2009, Shanghai. 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology. Shanghai, 2009. p. 223.

• Kaisarevic S. ; Dakic, V. ; Hrubik J. ; Gliisic B. ; Lübcke-von Varel U. ; Pogrmic K. ; Teodorovic I. ; Brack W. ; Kovacevic R. . Profiles of CYP1 and GST gene expression in rat hepatoma cells as biomarkers for discriminatiohn between contamination by polychlorinated diibenzo-p-dioxins and polycyclic aromatic hydrocarbons.. In: 11th Serbian Congress of Toxicology New Frontiers and Challenges in Toxicology, 2014, Sremski Karlovci, Serbia,. 11th Serbian Congress of Toxicology New Frontiers and Challenges in Toxicology, 2014.

• KAISAREVIC, S ; Dakic, V. ; Hrubik J. ; Pogrmic K. ; FA, S ; Gliisic B. ; Kovacevic R. . TCDD and PAH-induced CYP1A/B gene expression in H4IIE rat hepatoma cells. In: Congress of European Societies of Toxicology EUROTOX, 2012, Stockholm. ?Safety science serving society?, 2012.

Outras produções

Projetos de pesquisa

• 2012 - Atual

  MODELAGEM DA ESQUIZOFRENIA UTILIZANDO CÉLULAS-TRONCO DE PLURIPOTÊNCIA INDUZIDA (IPS) PARA APLICAÇÃO EM MEDICINA PERSONALIZADA, Descrição: Compreender o papel do metabolismo do oxigênio, e outros aspectos relacionados ao estresse oxidativo e desenvolvimento neuronal é de fundamental importância para elucidar fatores celulares e bioquímicos envolvidos em transtornos psiquiátricos e, principalmente, para a criação de plataformas de prospecção de compostos com potencial terapêutico para esquizofrenia.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Vanja Dakic - Integrante / Bruna Paulsen - Integrante / Renata Maciel - Integrante / Rodrigo Madeiro - Integrante / Stevens Rehen - Coordenador.

• 2011 - 2014

  Endocrine disrupting compounds: reproductive, metabolic, developmental responses and mechanism of action in selected model organisms and cell lines, Descrição: The endocrine-disrupting chemicals (EDCs) have capacity to alter the function of hormonal and homeostatic system. Issues key to understanding the mechanism of action of EDC exposure includes the critical windows of susceptibility of target tissues, latency from exposure, mixture effects, dose-response dynamics and long-term latent effects. Objectives of the projects are to study reproductive, metabolic and developmental effects of selected EDC and mixtures and mechanisms of action in several model organisms and cell types: 1. Rat Leydig cells: effect and mechanism of action of single and mixed EDCs on steroidogenesis during sexual development; 2. Human HepG2, Rat H4IIE and fish ZFL hepatocytes: toxicity, proliferative/apoptotic action of single EDC and mixtures; Aquatic organisms: effects of environmentally relevant concentrations of selected EDC and mixtures of Dafnia magna reproduction and growth of Myriophillum aquaticum in complex matrices of freshwater ecosystems; 4. Zebrafish: studies on xenobiotic metabolic pathways, with special focus on characterization of ecotoxicologically relevant phase II enzymes. The project is aimed not only to elucidate the effect of environmentally relevant EDCs and mixtures on critical metabolic pathways in mammalians and non-mammalian species, including human cells, but also the strengthen the potential of our research group in fundamental and applied ecophysiological research and in ecological risk assessment.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (4) / Mestrado acadêmico: (2) / Doutorado: (6) . , Integrantes: Vanja Dakic - Integrante / Pogrmic-Majkic K. - Integrante / Fa S. - Integrante / Hrubik J. - Integrante / Kaisarevic S. - Integrante / Kovacevic R. - Coordenador / Teodorovic I. - Integrante / Gliisic B. - Integrante., Financiador(es): University Of Novi Sad - Auxílio financeiro / Faculty of Sciences - Auxílio financeiro.

• 2010 - 2012

  Establishing and developing of an ecotoxicology platform in Serbia and Croatia: a focus on zebrafish (Danio rerio), Descrição: The main project goal is capacity-building and promoting ecotoxicological research groups in Serbia and Croatia, and this overall goal will be fulfilled by performing two core project activities. The first part of the project will be directed to the transfer of knowledge and expertise that will enable the Serbian and Croatian partners to improve their overall research capacity, performing part of the research using zebrafish (Danio rerio) and related cell lines as highly established and promising models in biomedical and ecotoxicological research. Stable zebrafish cell lines (PAC1 and ZFL) and related cell culture protocols will be transferred to partner laboratories in Serbia and Croatia. Graduate students from both countries will be trained in Switzerland, in order to get knowledge and skills needed for work with these cell culture systems. A small scale zebrafish facility will be established at the Serbian partner laboratory, and equipment needed for maintenance of fish cell cultures will be installed. Both Serbian and Croatian partners will acquire knowledge needed for performing classical zebrafish acute toxicity assays, as well as the recently established zebrafish embryotoxicity DarT test. The second part of the project, which is focused on research, will be directed to better understanding of critical cellular, evolutionary conserved xenobiotic defence systems in aquatic organisms, using zebrafish as a model. Aquatic organisms deploy a wide range of protective systems against the adverse effects of toxic chemicals originating from both exogenous (environment) and endogenous sources. Taking into account the complexity of defence mechanisms contributing to the overall adsorption, disposition, metabolism, excretion, and finally toxicity of xenobiotics, in this project we will specifically focus on the uptake of environmental chemicals and metabolites by specific transmembrane proteins, detoxification by phase I and II biotransformation enzyme systems; and fin. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Vanja Dakic - Integrante / Pogrmic-Majkic K. - Integrante / Fa S. - Integrante / Hrubik J. - Integrante / Kaisarevic S. - Integrante / Kovacevic R. - Coordenador / Teodorovic I. - Integrante / Gliisic B. - Integrante., Financiador(es): University Of Novi Sad - Outra.

• 2007 - 2009

  Reinforcement of research potential of the laboratory for ecotoxicology (REP-LECOTOX), Descrição: Laboratory for Ecotoxicology (LECOTOX) at the Faculty of Sciences, University of Novi Sad, represents qualified and very promising research capacity focused on toxic impact of persistent organic pollutants on biota with special emphases on fresh water ecosystem and sub-lethal types of toxicity (endocrine disruption, reproductive toxicity, and "dioxin-like" toxicity). The research activities of LECOTOX are identification and characterization of aquatic ecotoxicity in our region in accordance with modern scientific approach, environmental quality standards and criteria, and active participation in the sustainable development and a consistent environmental policy, which has an ultimate character in the case of country in transition such as Serbia. Objectives of the proposed project are collaboration with research institutions in EU, exchange of scientific personnel and the training of young scientists; hiring new young researches to reinforce the human resources; and upgrading and renewal of S&T equipment. Achievement of those goals should enable research group of LECOTOX to become ready for challenge in ecotoxicology, namely for ecotoxicogenomics, a study of gene and protein expression important in response to environmental toxicant exposure. Development and application of genomic-based tools to tackle ecotoxicological questions, and intensive collaboration among researchers throughout the world on that issue, indicate significance of orientation to such propulsive field of investigation. Realization of the project would facilitate integration of LECOTOX into the European research area (ERA) as an appropriate partner in fundamental as well as applied research projects and in future activities within FP7.. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Vanja Dakic - Integrante / Pogrmic-Majkic K. - Integrante / Fa S. - Integrante / Kaisarevic S. - Integrante / Kovacevic R. - Coordenador / Orcic D. - Integrante / Teodorovic I. - Integrante / Planojevic I. - Integrante., Financiador(es): University Of Novi Sad - Auxílio financeiro.

• 2006 - 2010

  ?Endocrine disruption chemicals ? effects on reproductive and thyroid function, environmental assessment by bioanalyses?,, Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (7) Doutorado: (5) . , Integrantes: Vanja Dakic - Integrante / Pogrmic-Majkic K. - Integrante / Fa S. - Integrante / Kaisarevic S. - Integrante / Kovacevic R. - Coordenador / Teodorovic I. - Integrante / Gliisic B. - Integrante., Financiador(es): Faculty of Sciences - Auxílio financeiro.

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