Cesario Bianchi Filho

Possui graduação em medicina pela Faculdade de Ciências Médicas da Santa Casa de São Paulo (1981), mestrado em patologia - Université de Montreal (1985) e doutorado em medicina experimental - McGill University [1989, reconhecido em 2014 pela Universidade Federal de Goiás (UFG)] como bolsista de graduação do Medical Research Council of Canada. Tem pós-doutorado em biologia molecular / cardiologia pelo Mass General Hospital / Harvard Medical School (1988-1991) como bolsista de Pós-graduação no exterior do Medical Research Council of Canada. Foi Instrutor em Medicina (1991-2000), Professor Assistente em Cirurgia / Medicina da Harvard Medical School (2001-2009) e Professor Associado de Cirurgia (Pesquisa) da Brown University (2009-2014). Foi cientista visitante na Harvard University, UFG e do Centro Nacional de Pesquisa em Energia e Materiais. É atualmente professor e pesquisador na Universidade de Mogi das Cruzes e Fellow do American Heart Association (FAHA).Tem experiência na área de Medicina, com ênfases em biologia celular e molecular do sistema cardiovascular, atuando principalmente nos seguintes temas: mecanismos celulares e moleculares nas complicações decorrentes de cirurgias cardiotorácicas, isquemia e reperfusão aguda do miocárdio, e mecanismos de alterações angiogênicas / vasculares do miocárdio cronicamente isquêmico em modelos experimentais de diabetes (tipos I e II) e hipercolesterolemia. Web of Science ResearchID H-6238-2012; 3710 citaçôes Fator H (34). Google Scholar 5350 citações; Fator H: (desde 2013: 21; total: 42).

Informações coletadas do Lattes em 26/10/2019

Acadêmico

Seção coletada automaticamente pelo Escavador

Formação acadêmica

Doutorado em experimental medicine

1984 - 1988

McGill University
Título: Localization and Distribution of Bindind Sites for Atrial Natriuretic Factor in Rat. A Light and Electron Microscope Radioautographic Study
Orientador: Marc Cantin
Bolsista do(a): Medical Research Council of Canada, MRC CANADA, Canadá.

Mestrado em patologia

1982 - 1985

Université de Montreal, UdeM
Título: La Liaison et L'internalization de L'angiotensine II dans le Cortex Surrenalien du Rat,Ano de Obtenção: 1985
Orientador: Marc Cantin
Bolsista do(a): Canadian Heart Foundation, CHF, Canadá.

Graduação em andamento em Direito

2016 - Atual

Universidade de Mogi das Cruzes

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Pós-doutorado

1989 - 1991

Pós-Doutorado. , Harvard Medical School, HMS, Estados Unidos. , Bolsista do(a): Medical Research Council of Canada, MRC CANADA, Canadá.

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Formação complementar

2019 - 2019

Extensão universitária em Evidence Based Practice Workshop EBCP. (Carga horária: 31h). , McMaster University, McMaster, Canadá.

2018 - 2018

FORUM NACIONAL DE ENSINO MEDICO. (Carga horária: 16h). , CONSELHO FEDERAL DE MEDICINA, CFM, Brasil.

Seção coletada automaticamente pelo Escavador

Idiomas

Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Espanhol

Compreende Bem, Fala Razoavelmente, Lê Bem, Escreve Pouco.

Português

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Italiano

Compreende Bem, Fala Razoavelmente, Lê Bem, Escreve Pouco.

Francês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Seção coletada automaticamente pelo Escavador

Áreas de atuação

    Grande área: Ciências da Saúde / Área: Medicina / Subárea: Cirurgia/Especialidade: Cirurgia Cardiovascular.

    Grande área: Ciências da Saúde / Área: Medicina / Subárea: Cirurgia/Especialidade: Cirurgia Experimental.

    Grande área: Ciências Biológicas / Área: Morfologia / Subárea: Citologia e Biologia Celular.

    Grande área: Ciências Biológicas / Área: Imunologia / Subárea: Imunoquímica.

    Grande área: Ciências da Saúde / Área: Medicina / Subárea: Anatomia Patológica e Patologia Clínica.

Seção coletada automaticamente pelo Escavador

Participação em eventos

XVII Feira da Saúde.Médico voluntário. 2017. (Oficina).

Congresso Medico Universitário de Mogi das Cruzes. Avaliador de Trabalhos Cientificos. 2016. (Congresso).

American Heart Association National Scientific Meeting. Rapamycin Treatment Regulates miRNAs Associated with mitochondrial and Endoplasmic Reticulum Functions in a Pig Model of Myocardial Ischemia/Reperfusion Injury. 2015. (Congresso).

Seção coletada automaticamente pelo Escavador

Participação em bancas

Aluno: Faustino Peron Filho

BIANCHI, CESÁRIO. "Estudo piloto de avaliação do perfil farmacodinâmico, segurança e tolerabilidade de uma formulação de testosterona (gel) para administração tópica em mulheres menopausadas. 2019. Dissertação (Mestrado em Farmacologia) - Universidade Estadual de Campinas.

Aluno: Priscila Martinez Monteiro

Bianchi, Cesario F.. Reserva Neuronal induzida pela prática de atividade física na adolescencia.: analise dos espinhos dendríticos. 2018.

Aluno: Priscila Martinez Monteiro

BIANCHI, C. Reserva Neural Induzida pela Prática de Atividade Física na Adolescência: Analise dos Espinhos Dendriticos. 2018. Dissertação (Mestrado em Engenharia Biomédica) - Universidade de Mogi das Cruzes.

Aluno: Mariana Machado Matos

Bianchi, Cesario F.. Estudo de biodisponibilidade comparativa da Capecitabina em participantes sadios dosexo masculino após alimentação. 2018. Dissertação (Mestrado em Farmacologia) - Universidade Estadual de Campinas.

Aluno: Reinaldo Batista dos Santos

BIANCHI, C. Avaliação do Efeito da Suplementação Alimentar com Substância Termogênica na Temperatura Corporal Através da Termografia Infrevermelha. 2018. Dissertação (Mestrado em Engenharia Biomédica) - Universidade de Mogi das Cruzes.

Aluno: Camila Ueda

BIANCHI, C. Efeitos do treinamento Físico na Termogênese do Tecido Adiposo Marrom e Branco. 2018. Dissertação (Mestrado em Biotecnologia) - Universidade de Mogi das Cruzes.

Aluno: [Nome removido após solicitação do usuário]

BIANCHI, C. Quantificação da 3alfa-hidroxitibolona no plasma humano por cromatografia l´quida de alta performance acoplada por espectrometria de massas com ionizaçao por electrospray (HPLC-ESI-MS/MS): aplicação em um estudo de bioequivalencia em voluntários sadios na pós-menopausa. 2017. Dissertação (Mestrado em Farmacologia) - Universidade Estadual de Campinas.

Aluno: Mônica Karla Vojta Miranda

BIANCHI, C. Influencia do estilo de vida e qualidade de vida nos marcadores biologicos. 2017. Dissertação (Mestrado em Mestrado em Promoção da Saúde) - Centro Universitário Adventista de São Paulo.

Aluno: Paulo Rogério de Oliveira

BIANCHI, C. Perfil Epidemiológico de Pacientes Gestantes de Ambulatório de Pré-Natal de Alto risco em Município de Barueri. 2017. Dissertação (Mestrado em Mestrado Profissional em Ciência e Tecnologia em Saúde) - Universidade de Mogi das Cruzes.

Aluno: Tânia Regina Cupaiolo Silva

Bianchi, Cesario F.. Diagnóstico Precoce da Atrofia Vulvo Vaginal em Mulheres Durante o Desenvolvimento da Menopausa. 2017. Dissertação (Mestrado em Mestrado Profissional em Ciência e Tecnologia em Saúde) - Universidade de Mogi das Cruzes.

Aluno: Antonio Carlos Ribeiro Filho

BIANCHI, C. F.. Caracterização da Presença e Função de Receptores P2 em Granulócitos Murinos e em Celulas-Tronco Leucêmicas Humanas. 2019. Tese (Doutorado em Biotecnologia) - Universidade de Mogi das Cruzes.

Aluno: Luana Garcia Leal Bueno

BIANCHI, C. Efeitos da Aplicação Terapeutica de um Programa de Treinamento Resistido em Camundongos cm Caquexia Associada ao Cancer. 2019. Tese (Doutorado em Engenharia Biomédica) - Universidade de Mogi das Cruzes.

Aluno: : Ana Paula Lima Perdigão

Bianchi, Cesario F.. AVALIAÇÃO FARMACOCINÉTICA DO RILUZOLE POR LC-MS/MS APÓS ADMINISTRAÇÃO DE DIFERENTES DOSES EM CÃES SADIOS DA RAÇA BEAGLE. 2019. Tese (Doutorado em Doutorado em Ciências Médicas) - Universidade Estadual de Campinas.

Aluno: Pamela Viegas Knobl

BIANCHI, C.. Caracterização Fenotípica e Possível Repercussãp no urnover de Lipídeos em Camundongos Nocautes para o Receptor Toll Like 4. 2018. Tese (Doutorado em Biotecnologia) - Universidade de Mogi das Cruzes.

Aluno: Renan Donomae Iwamoto

BIANCHI, C. Comparação da biodisponibilidade entre formulação-teste e formulação-referência de propafenona (Ritmonrom) em voluntários sadios de ambos os sexos selecionados fenotipicamente. 2018. Tese (Doutorado em Farmacologia) - Universidade Estadual de Campinas.

Aluno: Magno Alves Lopes

BIANCHI, C.. Avaliação do Papel do TLR4 na Diferenciação Celular do Adpócito frente à caquexia associada ao câncer. 2018. Tese (Doutorado em Biotecnologia) - Universidade de Mogi das Cruzes.

Aluno: Sílvio Roberto Consonni

Kleber Gomes Franchini; Paulo Pinto Joazeiro; Talita Miguel Marin;Bianchi, C.. Localização e função de quinase de adesão focal e calsarcina-1 em cardiomiócitos de ratos: emprego de sondas moleculares e lentivirus. 2015. Tese (Doutorado em Biologia Celular e Estrutural) - Universidade Estadual de Campinas.

Aluno: Vanessa de Souza Cruz Pimenta

ARAUJO, E. G.Bianchi, C.; MIGUEL, M. P.; Araujo, LBM; Dasmaceno, AD. Avaliação das propriedades antiproliferativas da Beta-Lapachona em cultura de células de osteossarcoma canino. 2015. Tese (Doutorado em Ciência Animal) - Universidade Federal de Goiás.

Aluno: Luana Garcia Leal Bueno

Bianchi, C.. Investigação do Potencial Terapeutico do Treinamento Resistido de Baixa Intensidade em Camundongos Portadores de Tumor como Intervenção à Caquexia Associada ao Câncer. 2019. Exame de qualificação (Doutorando em Engenharia Biomédica) - Universidade de Mogi das Cruzes.

Aluno: Sílvio Roberto Consonni

Paulo Pinto Joazeiro; Talita Miguel Marin;Bianchi, C.. Localização e função de quinase de adesão focal e calsarcina-1 em cardiomiócitos de ratos: emprego de sondas moleculares e lentivírus. 2015. Exame de qualificação (Doutorando em Biologia Celular e Estrutural) - Universidade Estadual de Campinas.

Aluno: Camila Weda

BIANCHI, C. Efeitos do treinamento físico na termogênese do tecido adiposo marrom e branco. 2018. Exame de qualificação (Mestrando em Biotecnologia) - Universidade de Mogi das Cruzes.

Aluno: Felipe de Oliveira Franco

BIANCHI, C. Perfil do Remodelamento do Tecido Adiposo Marrom em Resposta a Exposição ao Frio em Camundongos Nocautes para TLR4. 2017. Exame de qualificação (Mestrando em Engenharia Biomédica) - Universidade de Mogi das Cruzes.

Bianchi, C.. Avaliador de Trabalhos Científicos. 2016. Universidade de Mogi das Cruzes.

Seção coletada automaticamente pelo Escavador

Orientou

Julio Aguiar

Inteligência Artificial, Big Data e HIV; A Proteção dos Direitos Humanos na Era Digital; Início: 2019; Dissertação (Mestrado em Biotecnologia) - Universidade de Mogi das Cruzes; (Orientador);

Rogério de Carvalho

Manutenção farmacológica da pressão arterial via sistema supervisório cpmtrolado por computador; Início: 2019; Dissertação (Mestrado em Engenharia Biomédica) - Universidade de Mogi das Cruzes; (Orientador);

Reinaldo B

Santos; AVALIAÇÃO DO EFEITO DA SUPLEMENTAÇÃO ALIMENTAR COM SUBSTÂNCIAS TERMOGÊNICAS NA TEMPERATURA MUSCULAR ATRAVÉS DA TERMOGRAFIA INFRA-VERMELHA; Início: 2018; Dissertação (Mestrado em Engenharia Biomédica) - Universidade de Mogi das Cruzes; (Orientador);

Vanessa Martins de Oliveira

Aplicativo de Treinamento para o Preparação de Soluções Pediatricas; Início: 2018; Dissertação (Mestrado em Engenharia Biomédica) - Universidade de Mogi das Cruzes; (Orientador);

João Batista de Oliveira

Desenvolvimento, construção e validação de um sistema cardiovaascular; Início: 2018; Dissertação (Mestrado em Engenharia Biomédica) - Universidade de Mogi das Cruzes; (Orientador);

Fernanda Vieira de Oliveira

Quantificação da Vibices abdominais em Pacitentes Gravidas; Início: 2018; Dissertação (Mestrado em Engenharia Biomédica) - Universidade de Mogi das Cruzes; (Orientador);

Daniel Fernandes de Nóbrega

REDUÇÃO DO RISCO DE FALHA NA ASSISTÊNCIA A SAÚDE DE PACIENTES SUBMETIDOS A VENTILAÇÃO MECÂNICA PELA CONFIGURAÇÃO DE INTERFACE HOMEM MÁQUINA; Início: 2018; Tese (Doutorado em Engenharia Biomédica) - Universidade de Mogi das Cruzes; (Orientador);

Ricardo Martins

O Impacto da Biotecnologia no Ordenamento Jurídico; Início: 2018; Tese (Doutorado em Biotecnologia) - Universidade de Mogi das Cruzes; (Orientador);

Francini Rodrigues de Morais

Efeitos cardiovasculares do treinamento aeróbico em idosos; Início: 2018; Tese (Doutorado em Engenharia Biomédica) - Universidade de Mogi das Cruzes; (Orientador);

Maria de Lourdes Colacique da Silva Leme

Comparação das Leis de Patente entre Brasil e Estados Unidos; Início: 2017; Tese (Doutorado em Biotecnologia) - Universidade de Mogi das Cruzes; (Orientador);

Claudia Kumpel

Fibromialgia e arritmias cardiacas; Início: 2016; Tese (Doutorado em Engenharia Biomédica) - Universidade de Mogi das Cruzes; (Orientador);

Marcela Carreira

Alterações cardiologicas na caquexia induzida pelo cancer; Início: 2016; Iniciação científica (Graduando em Ciências Biológicas) - Universidade de Mogi das Cruzes; (Orientador);

Claudio de Lucia

American Heart Association Mentoring Partnership; Início: 2018; Orientação de outra natureza; Temple University; (Orientador);

Antonio Lassaletta

2013; Brown University, Rhode Island Hospital, Department of Health and Human Services; Cesario Bianchi Filho;

Louis Chu

2012; Brown University, Rhode Island Hospital, Department of Health and Human Services; Cesario Bianchi Filho;

Nassrene Elmadhun

2011; Brown University, Department of Health and Human Services; Cesario Bianchi Filho;

Shizu Oyamada

2011; Beth Israel Deaconess Medical Center,; Cesario Bianchi Filho;

Michael P Robich

2010; Beth Israel Deaconess Medical Center, Department of Health and Human Services; Cesario Bianchi Filho;

Robert Osipov

2009; Beth Israel Deaconess Medical Center, Department of Health and Human Services; Cesario Bianchi Filho;

Wesley Durand

Effect of fat acids on autophagic flux in endothelial cells; 2014; Trabalho de Conclusão de Curso; (Graduação em Medicine) - Brown University, Department of Health and Human Services; Orientador: Cesario Bianchi Filho;

Marcela Janaina de Oliveira Araujo Careira

Analise dos efeitos da caquexia associada ao câncer em cèlulas cardiacas; 2017; Iniciação Científica; (Graduando em Ciências Biológicas) - Universidade de Mogi das Cruzes, Conselho Nacional de Desenvolvimento Científico e Tecnológico; Orientador: Cesario Bianchi Filho;

Thomas Burgess

Resveratrol role in liver and skeletal muscle metabolism; 2012; Iniciação Científica - Brown University, Rhode Island Hospital; Orientador: Cesario Bianchi Filho;

Rahul Dalal

Metformin and chronic myocardial ischemia; 2012; Iniciação Científica; (Graduando em Medicine) - Brown University; Orientador: Cesario Bianchi Filho;

Nicholas Karson

Effect of alcohol on chronic myocardial ischemia; 2012; Iniciação Científica; (Graduando em Medicine) - Brown University; Orientador: Cesario Bianchi Filho;

Robert Hein IV

Effects of free fat acids in mTOR activity in vascular cells in culture; 2012; Iniciação Científica; (Graduando em Medicine) - Brown University, Department of Health and Human Services; Orientador: Cesario Bianchi Filho;

Zachary Hoffman

Effect of Rapamycin in acute ischemia-reperfusion injury; 2011; Iniciação Científica; (Graduando em Medicine) - Brown University; Orientador: Cesario Bianchi Filho;

David Kim

Effect of alcohol on chronic myocardial ischemia; 2011; Iniciação Científica; (Graduando em Medicine) - Brown University, Department of Health and Human Services; Orientador: Cesario Bianchi Filho;

Ina Soh

Cardiac DNA methylation in Hypercholesterolemia; 2010; Iniciação Científica; (Graduando em Medicine) - Brown University, Department of Health and Human Services; Orientador: Cesario Bianchi Filho;

ROBERT E

Hein IV; Resveratrol and hypercholesterolemia; 2010; Iniciação Científica; (Graduando em Medicine) - Brown University; Orientador: Cesario Bianchi Filho;

Alicia Chen

Resveratrol and hypercholesterolemia; 2010; Iniciação Científica; (Graduando em Medicine) - Brown University, Department of Health and Human Services; Orientador: Cesario Bianchi Filho;

Tai Ho Chin

Resveratrol role in heart metabolism; 2009; Iniciação Científica; (Graduando em Medicine) - Brown University, Department of Health and Human Services; Orientador: Cesario Bianchi Filho;

Mirnal Chaudhary

Rapamycin and cardiomyocyte hypoxia; 2009; Orientação de outra natureza - Brown University, Rhode Island Hospital; Orientador: Cesario Bianchi Filho;

Hilary Glazer

Cardiac mTOR and Hypercholesterolemia; 2009; Orientação de outra natureza - Beth Israel Deaconess Medical Center; Orientador: Cesario Bianchi Filho;

Seção coletada automaticamente pelo Escavador

Produções bibliográficas

  • Bianchi, Cesario F. . Working toward an evidence-based cutoff recommendation for myocardial infarction detection after cardiac surgery. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY , v. 155, p. 1055, 2018.

  • SIMÃO, RICARDO SILVA ; ALVES, RAFAELA FERREIRA DE AZEVEDO ; BOSCHI, SILVIA REGINA MATOS DA SILVA ; SCARDOVELLI, TERIGI AUGUSTO ; RODRIGUES, SILVIA CRISTINA MARTINI ; BIANCHI, CESÁRIO ; SILVA, ALESSANDRO PEREIRA DA . Multiple Sclerosis: Comparison of the Conventional Spin-Echo T2-Weighted and Flair Techniques Through Image Processing. Journal of Medical Imaging and Health Informatics , v. 8, p. 425-430, 2018.

  • Bianchi, Cesario F. ; PETRUCCI, ORLANDO . A better treatment for saphenous vein graft disease after coronary artery bypass surgery: Might statins be the answer at the right dose to the right patient at the right time?. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY , v. xx, p. xxxx-xx, 2018.

  • SILVA, DIEGO PEREIRA DA ; AMATE, FLAVIO CEZAR ; BASILE, FELIPE RODRIGUES MARTINÊZ ; BIANCHI FILHO, CESÁRIO ; RODRIGUES, SILVIA CRISTINA MARTINI ; BISSACO, MARCIA APARECIDA SILVA . AACVOX: mobile application for augmentative alternative communication to help people with speech disorder and motor impairment. RESEARCH ON BIOMEDICAL ENGINEERING , v. 34, p. 166-175, 2018.

  • BIANCHI, C. F. . β Lapachone blocks the cell cycle and induces apoptosis in canine osteosarcoma cells. PESQUISA VETERINARIA BRASILEIRA , v. 38, p. 2224-2232, 2018.

  • FRANCO, FELIPE DE OLIVEIRA ; LOPES, MAGNO ALVES ; HENRIQUES, FELIPE DOS SANTOS ; NEVES, RODRIGO X ; BIANCHI FILHO, CESÁRIO ; BATISTA JÚNIOR, MIGUEL LUIZ . Cancer cachexia differentially regulates visceral adipose tissue turnover. Journal of Endocrinology , v. 232, p. JOE-16-0305-493, 2017.

  • Bianchi, Cesario F. . Time to dot the I´s and cross the T's of high sensitivity cardiac troponin. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY , v. S0022, p. 5223(17)3, 2017.

  • SABE, ASHRAF A. ; Elmadhun, Nassrene Y. ; SADEK, AHMED A. ; DALAL, RAHUL S. ; Chu, Louis M. ; Bianchi, Cesario ; Sellke, Frank W. . Atorvastatin Regulates Apoptosis in Chronically Ischemic Myocardium. Journal of Cardiac Surgery , v. 30, p. 218-223, 2015.

  • SABE, ASHRAF A. ; SADEK, AHMED A. ; Elmadhun, Nassrene Y. ; DALAL, RAHUL S. ; Robich, Michael P. ; Bianchi, Cesario ; Sellke, Frank W. . Investigating the Effects of Resveratrol on Chronically Ischemic Myocardium in a Swine Model of Metabolic Syndrome: A Proteomics Analysis. Journal of Medicinal Food , v. 18, p. 60-66, 2015.

  • Bianchi, Cesario F. ; PETRUCCI, ORLANDO . Another off-label NOAC to HIT cardiac surgery patients. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 15, p. 715, 2015.

  • LANGE, MARTIN ; FUJIKAWA, TATSUYA ; KOULOVA, ANNA ; KANG, SONA ; GRIFFIN, MICHAEL J ; LASSALETTA, ANTONIO D ; ERAT, ANNA ; TOBIASCH, EDDA ; Bianchi, Cesario ; ELMADHUN, NASSRENE ; Sellke, Frank W ; USHEVA, ANNY . Arterial territory-specific phosphorylated retinoblastoma protein species and CDK2 promote differences in the vascular smooth muscle cell response to mitogens. Cell Cycle (Georgetown, Online) , v. 13, p. 315-323, 2014.

  • Lassaletta, Antonio D. ; Elmadhun, Nassrene Y. ; Burgess, Thomas A. ; Bianchi, Cesario ; SABE, ASHRAF A. ; Robich, Michael P. ; Chu, Louis M. ; Sellke, Frank W. . Microvascular Notch Signaling Is Upregulated in Response to Vascular Endothelial Growth Factor and Chronic Myocardial Ischemia. Circulation Journal , v. 78, p. 743-751, 2014.

  • SABE, ASHRAF A. ; Elmadhun, Nassrene Y. ; Sadek AA ; Chu, L. M. ; Bianchi, C. ; Sellke, Frank W . Differential effects of atorvastatin on autophagy in ischemic and nonischemic myocardium in Ossabaw swine with metabolic syndrome. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 148, p. 3172-3178, 2014.

  • SABE, ASHRAF A. ; DALAL, RAHUL S. ; Chu, Louis M. ; Elmadhun, Nassrene Y. ; Ramlawi, Basel ; Bianchi, Cesario ; Sellke, Frank W. . Preoperative gene expression may be associated with neurocognitive decline after cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 149, p. 613-623, 2014.

  • Feng, Jun ; Liu, Yuhong ; DOBRILOVIC, NIKOLA ; SINGH, ARUN K. ; SABE, ASHRAF A. ; GUAN, YINGJIE ; Bianchi, Cesario ; Sellke, Frank W. . Altered expression and activation of mitogen-activated protein kinases in diabetic heart during cardioplegic arrest and cardiopulmonary bypass. Surgery , v. 154, p. 436-443, 2013.

  • Shafique, Ehtesham ; Choy, Wing C ; Liu, Yuhong ; Feng, Jun ; Cordeiro, Brenda ; Lyra, Arthur ; Arafah, Mohammed ; Yassin-Kassab, Abdulmounem ; Zanetti, Arthus V D ; Clements, Richard T ; BIANCHI, C ; Benjamin, Laura E ; Sellke, Frank W . Oxidative stress improves coronary endothelial function through activation of the pro-survival kinase AMPK. Aging-US , v. 5, p. 515-530, 2013.

  • Feng, J. ; Liu, Y. ; Dobrilovic, N. ; Chu, L. M. ; Bianchi, C. ; Singh, A. K. ; SELLKE, F. W. . Altered Apoptosis-Related Signaling After Cardioplegic Arrest in Patients With Uncontrolled Type 2 Diabetes Mellitus. Circulation (New York, N.Y.) , v. 128, p. S144-S151, 2013.

  • Lassaletta, Antonio D. ; Elmadhun, Nassrene Y. ; ZANETTI, ARTHUS V.D. ; Feng, Jun ; ANDUAGA, JAVIER ; GOHH, REGINALD Y. ; Sellke, Frank W. ; Bianchi, Cesario . Rapamycin Treatment of Healthy Pigs Subjected to Acute Myocardial Ischemia-Reperfusion Injury Attenuates Cardiac Functions and Increases Myocardial Necrosis. The Annals of Thoracic Surgery , v. 4975, p. 02146, 2013.

  • Chu, L. M. ; Robich, M. P. ; BIANCHI, C. ; FENG, J. ; Liu, Y. ; Xu, S.-H. ; Burgess, T. ; SELLKE, F. W. . Effects of cyclooxygenase inhibition on cardiovascular function in a hypercholesterolemic swine model of chronic ischemia. American Journal of Physiology. Heart and Circulatory Physiology , v. 302, p. H479-H488, 2012.

  • Riolo, M. T. ; Cooper, Z. A. ; Holloway, M. P. ; Cheng, Y. ; BIANCHI, C. ; Yakirevich, E. ; Ma, L. ; Chin, Y. E. ; Altura, R. A. . Histone Deacetylase 6 (HDAC6) Deacetylates Survivin for Its Nuclear Export in Breast Cancer. Journal of Biological Chemistry (Online) , v. 287, p. 10885-10893, 2012.

  • Stoeckius, M. ; Erat, A. ; Fujikawa, T. ; Hiromura, M. ; Koulova, A. ; Otterbein, L. ; BIANCHI, C. ; Tobiasch, E. ; Dagon, Y. ; SELLKE, F. W. ; Usheva, A. . Essential Roles of Raf/Extracellular Signal-regulated Kinase/Mitogen-activated Protein Kinase Pathway, YY1, and Ca2+ Influx in Growth Arrest of Human Vascular Smooth Muscle Cells by Bilirubin. Journal of Biological Chemistry (Online) , v. 287, p. 15418-15426, 2012.

  • Elmadhun, Nassrene Y. ; Lassaletta, Antonio D. ; Chu, Louis M. ; Bianchi, Cesario ; Sellke, Frank W. . Vodka and wine consumption in a swine model of metabolic syndrome alters insulin signaling pathways in the liver and skeletal muscle. Surgery , v. 152, p. 414-422, 2012.

  • FENG, J. ; Liu, Y. ; Chu, L. M. ; Singh, A. K. ; Dobrilovic, N. ; Fingleton, J. G. ; CLEMENTS, R. T. ; BIANCHI, C. ; SELLKE, F. W. . Changes in Microvascular Reactivity After Cardiopulmonary Bypass in Patients With Poorly Controlled Versus Controlled Diabetes. Circulation (Online) , v. 126, p. S73-S80, 2012.

  • Robich, Michael P ; Chu, Louis M ; Burgess, Thomas A ; Feng, Jun ; Bianchi, Cesario ; Sellke, Frank W . Effects of Selective Cyclooxygenase-2 and Nonselective Cyclooxygenase Inhibition on Myocardial Function and Perfusion. Journal of Cardiovascular Pharmacology , v. 57, p. 122-130, 2011.

  • Feng, Jun ; Liu, Yuhong ; Khabbaz, Kamal R. ; Hagberg, Robert ; Robich, Michael P. ; Clements, Richard T. ; Bianchi, Cesario ; Sellke, Frank W. . Decreased contractile response to endothelin-1 of peripheral microvasculature from diabetic patients. Surgery , v. 149, p. 247-252, 2011.

  • Oyamada, Shizu ; Ma, Xiaodong ; Wu, Tim ; Robich, Michael P. ; Wu, Hao ; Wang, Xingwei ; Buchholz, Bryan ; McCarthy, Stephen ; Bianchi, Cesario F. ; Sellke, Frank W. ; Laham, Roger . Trans-Iliac Rat Aorta Stenting: A Novel High Throughput Preclinical Stent Model for Restenosis and Thrombosis. The Journal of Surgical Research (Print) , v. 166, p. e91-e95, 2011.

  • Ma, Xiaodong ; Oyamada, Shizu ; Wu, Tim ; Robich, Michael P. ; Wu, Hao ; Wang, Xingwei ; Buchholz, Bryan ; McCarthy, Stephen ; Bianchi, Cesario F. ; Sellke, Frank W. ; Laham, Roger . In vitro and in vivo degradation of poly(D, L-lactide-co-glycolide)/amorphous calcium phosphate copolymer coated on metal stents. Journal of Biomedical Materials Research. Part A , v. 96A, p. 632-638, 2011.

  • Ma, Xiaodong ; Oyamada, Shizu ; Gao, Fan ; Wu, Tim ; Robich, Michael P. ; Wu, Hao ; Wang, Xingwei ; Buchholz, Bryan ; McCarthy, Stephen ; Gu, Zhiyong ; Bianchi, Cesario F. ; Sellke, Frank W. ; Laham, Roger . Paclitaxel/sirolimus combination coated drug-eluting stent: In vitro and in vivo drug release studies. Journal of Pharmaceutical and Biomedical Analysis (Print) , v. 54, p. 807-811, 2011.

  • CLEMENTS, R. T. ; FENG, J. ; Cordeiro, B. ; BIANCHI, C. ; SELLKE, F. W. . p38 MAPK-dependent small HSP27 and  B-crystallin phosphorylation in regulation of myocardial function following cardioplegic arrest. American Journal of Physiology. Heart and Circulatory Physiology , v. 300, p. H1669-H1677, 2011.

  • Burgess, Thomas A ; Robich, Michael P ; Chu, Louis M ; BIANCHI, C ; Sellke, Frank W . Improving glucose metabolism with resveratrol in a swine model of metabolic syndrome through alteration of signaling pathways in the liver and skeletal muscle.. Archives of Surgery (Chicago. 1960) , v. 146, p. 556-564, 2011.

  • Matyal, Robina ; Mahmood, Feroze ; Robich, Michael ; Glazer, Hiliary ; Khabbaz, Kamal ; Hess, Philip ; Bianchi, Cesario ; Hagberg, Robert ; Hu, Shu-Xu ; Sellke, Frank W. . Chronic type II diabetes mellitus leads to changes in neuropeptide Y receptor expression and distribution in human myocardial tissue. European Journal of Pharmacology , v. 665, p. 19-28, 2011.

  • Feng, Jun ; Liu, Yuhong ; Chu, Louis M. ; Clements, Richard T. ; Khabbaz, Kamal R. ; Robich, Michael P. ; Bianchi, Cesario ; Sellke, Frank W. . Thromboxane-Induced Contractile Response of Human Coronary Arterioles Is Diminished After Cardioplegic Arrest. The Annals of Thoracic Surgery , v. 92, p. 829-836, 2011.

  • Oyamada, S. ; BIANCHI, C. ; Takai, S. ; Chu, L. M. ; SELLKE, F. W. . Chymase Inhibition Reduces Infarction and Matrix Metalloproteinase-9 Activation and Attenuates Inflammation and Fibrosis after Acute Myocardial Ischemia/Reperfusion. The Journal of Pharmacology and Experimental Therapeutics (Online) , v. 339, p. 143-151, 2011.

  • CLEMENTS, R. T. ; Cordeiro, B. ; FENG, J. ; BIANCHI, C. ; SELLKE, F. W. . Rottlerin Increases Cardiac Contractile Performance and Coronary Perfusion Through BKCa++ Channel Activation After Cold Cardioplegic Arrest in Isolated Hearts. Circulation (Online) , v. 124, p. S55-S61, 2011.

  • Oyamada, Shizu ; BIANCHI, C. ; Takai, Shinji ; Robich, Michael P. ; Clements, Richard T. ; Chu, Louis ; Sellke, Frank W. . Impact of acute myocardial ischemia reperfusion on the tissue and blood-borne renin angiotensin system. Basic Research in Cardiology (Print) , v. 105, p. 513-522, 2010.

  • Robich, M. P. ; Osipov, R. M. ; Nezafat, R. ; FENG, J. ; CLEMENTS, R. T. ; BIANCHI, C. ; BOODHWANI, M. ; Coady, M. A. ; Laham, R. J. ; SELLKE, F. W. . Resveratrol Improves Myocardial Perfusion in a Swine Model of Hypercholesterolemia and Chronic Myocardial Ischemia. Circulation (New York, N.Y.) , v. 122, p. S142-S149, 2010.

  • Robich, Michael P. ; Matyal, Robina ; Chu, Louis M. ; Feng, Jun ; Xu, Shu-Hua ; Laham, Roger J. ; Hess, Philip E. ; Bianchi, Cesario ; Sellke, Frank W. . Effects of neuropeptide Y on collateral development in a swine model of chronic myocardial ischemia. Journal of Molecular and Cellular Cardiology , v. 49, p. 1022-1030, 2010.

  • Robich, Michael P. ; Chu, Louis M. ; Feng, Jun ; Burgess, Thomas A. ; Laham, Roger J. ; Bianchi, Cesario ; Sellke, Frank W. . Effects of selective cyclooxygenase-2 and nonselective cyclooxygenase inhibition on ischemic myocardium. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 140, p. 1143-1152, 2010.

  • Chu, Louis M. ; Osipov, Robert M. ; Robich, Michael P. ; Feng, Jun ; Oyamada, Shizu ; Bianchi, Cesario ; Sellke, Frank W. . Is hyperglycemia bad for the heart during acute ischemia?. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 140, p. 1345-1352, 2010.

  • Oyamada, S. ; Osipov, R. ; BIANCHI, C. ; Robich, M. P. ; FENG, J. ; Liu, Y. ; Burgess, T. A. ; Bell, T. M. ; Sheller, M. R. ; SELLKE, F. W. . Effect of Dimerized Thrombin Fragment TP508 on Acute Myocardial Ischemia Reperfusion Injury in Hypercholesterolemic Swine. The Journal of Pharmacology and Experimental Therapeutics (Print) , v. 334, p. 449-459, 2010.

  • Robich, Michael P. ; Araujo, Eugenio G. ; Feng, Jun ; Osipov, Robert M. ; Clements, Richard T. ; Bianchi, Cesario ; Sellke, Frank W. . Altered coronary microvascular serotonin receptor expression after coronary artery bypass grafting with cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 139, p. 1033-1040, 2010.

  • Osipov, R. M. ; BIANCHI, C. ; FENG, J. ; CLEMENTS, R. T. ; Liu, Y. ; Robich, M. P. ; Glazer, H. P. ; SODHA, N. R. ; SELLKE, F. W. . Effect of Hypercholesterolemia on Myocardial Necrosis and Apoptosis in the Setting of Ischemia-Reperfusion. Circulation (New York, N.Y.) , v. 120, p. S22-S30, 2009.

  • Ramlawi, Basel ; Otu, Hasan ; Russo, Mark J. ; Novick, Richard J. ; Bianchi, Cesario ; Sellke, Frank W. . Aprotinin Attenuates Genomic Expression Variability Following Cardiac Surgery. Journal of Cardiac Surgery , v. 24, p. 772-780, 2009.

  • Sodha, Neel R. ; Clements, Richard T. ; Feng, Jun ; Liu, Yuhong ; Bianchi, Cesario ; Horvath, Eszter M. ; Szabo, Csaba ; Stahl, Gregory L. ; Sellke, Frank W. . Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 138, p. 977-984, 2009.

  • Osipov, Robert M ; Robich, Michael P ; Feng, Jun ; Liu, Yuhong ; Clements, Richard T ; Glazer, Hilary P ; Sodha, Neel R ; Szabo, Csaba ; Bianchi, Cesario ; Sellke, Frank W . Effect of Hydrogen Sulfide in a Porcine Model of Myocardial Ischemia-Reperfusion: Comparison of Different Administration Regimens and Characterization of the Cellular Mechanisms of Protection. Journal of Cardiovascular Pharmacology , v. 54, p. 287-297, 2009.

  • Emani, Sirisha ; Ramlawi, Basel ; Sodha, Neel R. ; Li, Jian ; Bianchi, Cesario ; Sellke, Frank W. . Increased vascular permeability after cardiopulmonary bypass in patients with diabetes is associated with increased expression of vascular endothelial growth factor and hepatocyte growth factor. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 138, p. 185-191, 2009.

  • Osipov, R. M. ; Robich, M. P. ; FENG, J. ; CLEMENTS, R. T. ; Liu, Y. ; Glazer, H. P. ; Wagstaff, J. ; BIANCHI, C. ; SELLKE, F. W. . Effect of thrombin fragment (TP508) on myocardial ischemia-reperfusion injury in hypercholesterolemic pigs. Journal of Applied Physiology (1985) , v. 106, p. 1993-2001, 2009.

  • Osipov, Robert M. ; Bianchi, Cesario ; Clements, Richard T. ; Feng, Jun ; Liu, Yuhong ; Xu, Shu-Hua ; Robich, Michael P. ; Wagstaff, John ; Sellke, Frank W. . Thrombin Fragment (TP508) Decreases Myocardial Infarction and Apoptosis After Ischemia Reperfusion Injury. The Annals of Thoracic Surgery , v. 87, p. 786-793, 2009.

  • Clements, Richard T. ; Sodha, Neel R. ; Feng, Jun ; Boodhwani, Munir ; Liu, Yuhong ; Mieno, Shigetoshi ; Khabbaz, Kamal R. ; Bianchi, Cesario ; Sellke, Frank W. . Impaired Coronary Microvascular Dilation Correlates with Enhanced Vascular Smooth Muscle MLC Phosphorylation in Diabetes1. Microcirculation (New York, N.Y. 1994) , v. 16, p. 193-206, 2009.

  • Glazer, Hilary P. ; Osipov, Robert M. ; Clements, Richard T. ; Sellke, Frank W. ; Bianchi, Cesario . Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling. Cell Cycle (Georgetown, Tex.) , v. 8, p. 1738-1746, 2009.

  • Wykrzykowska, Joanna J. ; Bianchi, Cesario ; Sellke, Frank W. . Impact of Aging on the Angiogenic Potential of the Myocardium: Implications for Angiogenic Therapies with Emphasis on Sirtuin Agonists. Recent Patent Reviews on Cardiovascular Drug Discovery , v. 4, p. 119-132, 2009.

  • CLEMENTS, R. T. ; Smejkal, G. ; SODHA, N. R. ; Ivanov, A. R. ; Asara, J. M. ; FENG, J. ; Lazarev, A. ; Gautam, S. ; Senthilnathan, V. ; Khabbaz, K. R. ; BIANCHI, C. ; SELLKE, F. W. . Pilot Proteomic Profile of Differentially Regulated Proteins in Right Atrial Appendage Before and After Cardiac Surgery Using Cardioplegia and Cardiopulmonary Bypass. Circulation (New York, N.Y.) , v. 118, p. S24-S31, 2008.

  • MIENO, S ; CLEMENTS, R ; BOODHWANI, M ; SODHA, N ; RAMLAWI, B ; BIANCHI, C ; SELLKE, F . Characteristics and Function of Cryopreserved Bone Marrow Derived Endothelial Progenitor Cells. The Annals of Thoracic Surgery , v. 85, p. 1361-1366, 2008.

  • KHABBAZ, K ; FENG, J ; BOODHWANI, M ; CLEMENTS, R ; BIANCHI, C ; SELLKE, F . Nonischemic myocardial acidosis adversely affects microvascular and myocardial function and triggers apoptosis during cardioplegia. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 135, p. 139-146, 2008.

  • SODHA, N ; CLEMENTS, R ; BIANCHI, C ; SELLKE, F . Cardiopulmonary Bypass with Cardioplegic Arrest Activates Protein Kinase C in the Human Myocardium. Journal of the American College of Surgeons , v. 206, p. 33-41, 2008.

  • Sodha, Neel R. ; Clements, Richard T. ; Feng, Jun ; Liu, Yuhong ; Bianchi, Cesario ; Horvath, Eszter M. ; Szabo, Csaba ; Sellke, Frank W. . The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia reperfusion injury . European Journal of Cardio-Thoracic Surgery , v. 33, p. 906-913, 2008.

  • Sodha, Neel R. ; Boodhwani, Munir ; Ramlawi, Basel ; Clements, Richard T. ; Mieno, Shigetoshi ; Feng, Jun ; Xu, Shu-Hua ; Bianchi, Cesario ; Sellke, Frank W. . Atorvastatin Increases Myocardial Indices of Oxidative Stress in a Porcine Model of Hypercholesterolemia and Chronic Ischemia. Journal of Cardiac Surgery , v. 23, p. 312-320, 2008.

  • SODHA, N. R. ; CLEMENTS, R. T. ; BOODHWANI, M. ; Xu, S.-H. ; Laham, R. J. ; BIANCHI, C. ; SELLKE, F. W. . Endostatin and angiostatin are increased in diabetic patients with coronary artery disease and associated with impaired coronary collateral formation. American Journal of Physiology. Heart and Circulatory Physiology , v. 296, p. H428-H434, 2008.

  • HOENIG, M. R. ; BIANCHI, C. ; SELLKE, F. W. . Hypoxia Inducible Factor-1α, Endothelial Progenitor Cells, Monocytes, Cardiovascular Risk, Wound Healing, Cobalt and Hydralazine: A Unifying Hypothesis. CURRENT DRUG TARGETS , v. 9, p. 422-435, 2008.

  • Hoenig, Michel R. ; Bianchi, Cesario ; Rosenzweig, Anthony ; Sellke, Frank W. . The Cardiac Microvasculature in Hypertension, Cardiac Hypertrophy and Diastolic Heart Failure. Current Vascular Pharmacology , v. 6, p. 292-300, 2008.

  • Hoenig, Michel R. ; Bianchi, Cesario ; Rosenzweig, Anthony ; Sellke, Frank W. . Decreased Vascular Repair and Neovascularization with Ageing: Mechanisms and Clinical Relevance with an Emphasis on Hypoxia- Inducible Factor-1. Current Molecular Medicine , v. 8, p. 754-767, 2008.

  • Boodhwani, Munir ; Voisine, Pierre ; Ruel, Marc ; Sodha, Neel R. ; Feng, Jun ; Xu, Shu-Hua ; Bianchi, Cesario ; Sellke, Frank W. . Comparison of vascular endothelial growth factor and fibroblast growth factor-2 in a swine model of endothelial dysfunction---. European Journal of Cardio-Thoracic Surgery , v. 33, p. 645-650, 2008.

  • KHAN, T. ; BIANCHI, C. ; RUEL, M. ; FENG, J. ; SELLKE, F. W. . Differential effects on the mesenteric microcirculatory response to vasopressin and phenylephrine after cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 133, p. 682-688, 2007.

  • Clements, Richard T. ; Sodha, Neel R. ; Feng, Jun ; Mieno, Shigetoshi ; Boodhwani, Munir ; Ramlawi, Basel ; Bianchi, Cesario ; Sellke, Frank W. . Phosphorylation and translocation of heat shock protein 27 and ?B-crystallin in human myocardium after cardioplegia and cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 134, p. 1461-1470.e3, 2007.

  • RAMLAWI, B ; OTU, H ; RUDOLPH, J ; MIENO, S ; KOHANE, I ; CAN, H ; LIBERMANN, T ; MARCANTONIO, E ; BIANCHI, C ; SELLKE, F . Genomic expression pathways associated with brain injury after cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 134, p. 996-1005.e4, 2007.

  • RAMLAWI, B ; OTU, H ; MIENO, S ; BOODHWANI, M ; SODHA, N ; CLEMENTS, R ; BIANCHI, C ; SELLKE, F . Oxidative Stress and Atrial Fibrillation After Cardiac Surgery: A Case-Control Study. The Annals of Thoracic Surgery , v. 84, p. 1166-1173, 2007.

  • SODHA, N ; FENG, J ; CLEMENTS, R ; BIANCHI, C ; BOODHWANI, M ; RAMLAWI, B ; MIENO, S ; KHABBAZ, K ; SELLKE, F . Protein kinase C alpha modulates microvascular reactivity in the human coronary and skeletal microcirculation. Surgery , v. 142, p. 243-252, 2007.

  • RAMLAWI, B. ; RUDOLPH, J. L. ; MIENO, S. ; BOODHWANI, M. ; KHABBAZ, K. ; LEVKOFF, S. E. ; MARCANTONIO, E. R. ; BIANCHI, C. ; SELLKE, F. W. . C-Reactive protein and inflammatory response associated to neurocognitive decline following cardiac surgery. Surgery , v. 140, p. 221-226, 2006.

  • RAMLAWI, B. ; FENG, J. ; MIENO, S. ; SZABO, C. ; ZSENGELLER, Z. ; CLEMENTS, R. T. ; SODHA, N. R. ; BOODHWANI, M. ; BIANCHI, C. ; SELLKE, F. W. . Indices of apoptosis activation after blood cardioplegia and cardiopulmonary bypass. Circulation (New York, N.Y.) , v. 114, p. I257-I263, 2006.

  • FENG, J. ; SELLKE, M. E. ; RAMLAWI, B. ; BOODHWANI, M. ; CLEMENTS, R. T. ; LI, J. ; BIANCHI, C. ; SELLKE, F. W. . Bradykinin induces microvascular preconditioning through the opening of calcium-activated potassium channels. Surgery , v. 140, p. 192-197, 2006.

  • BOODHWANI, M. ; NAKAI, Y. ; VOISINE, P. ; FENG, J. ; LI, J. ; MIENO, S. ; RAMLAWI, B. ; BIANCHI, C. ; LAHAM, R. ; SELLKE, F. W. . High-dose atorvastatin improves hypercholesterolemic coronary endothelial dysfunction without improving the angiogenic response. Circulation (New York, N.Y.) , v. 4, p. I402-I408, 2006.

  • MIENO, S. ; RAMLAWI, B. ; BOODHWANI, M. ; CLEMENTS, R. T. ; MINAMIMURA, K. ; MAKI, T. ; XU, S. H. ; BIANCHI, C. ; LI, J. ; SELLKE, F. W. . Role of stromal-derived factor-1alpha in the induction of circulating CD34+CXCR4+ progenitor cells after cardiac surgery. Circulation (New York, N.Y.) , v. 414, p. I186-I192, 2006.

  • MIENO, S. ; BOODHWANI, M. ; RAMLAWI, B. ; LI, J. ; BIANCHI, C. ; LAHAM, R. ; SELLKE, F. W. . Human coronary microvascular effects of cardioplegia-induced stromal-derived factor-1alpha.. The Annals of Thoracic Surgery , v. 82, p. 657-663, 2006.

  • BOODHWANI, M. ; NAKAI, Y. ; MIENO, S. ; VOISINE, P. ; BIANCHI, C. ; ARAUJO, E. G. ; FENG, J. ; MICHAEL, K. ; LI, J. ; SELLKE, F. W. . Hypercholesterolemia impairs the myocardial angiogenic response in a swine model of chronic ischemia: role of endostatin and oxidative stress. The Annals of Thoracic Surgery , v. 81, p. 634-641, 2006.

  • Sodha, Neel R ; Boodhwani, Munir ; Bianchi, Cesario ; Ramlawi, Basel ; Sellke, Frank W . Aprotinin in cardiac surgery. Expert Review of Cardiovascular Therapy , v. 4, p. 151-160, 2006.

  • VOISINE, P. ; LI, J. ; BIANCHI, C. ; KHAN, T. ; RUEL, M. ; XU, S. H. ; FENG, J. ; ROSINBERG, A. ; MALIK, T. ; NAKAI, Y. ; SELLKE, F. W. . Effects of L-arginine on fibroblast growth factor 2-induced angiogenesis in a model of endothelial dysfunction.. Circulation (New York) , v. 30, p. I202-I207, 2005.

  • KHAN, T. ; BIANCHI, C. ; ARAUJO, E. G. ; VOISINE, P. ; XU, S. H. ; FENG, J. ; LI, J. ; SELLKE, F. W. . Aprotinin preserves cellular junctions and reduces myocardial edema after regional ischemia and cardioplegic arrest. Circulation (New York, N.Y.) , v. 30, p. I196-I201, 2005.

  • FENG, J. ; BIANCHI, C. ; SANDMEYER, J. ; LI, J. ; SELLKE, F. W. . Molecular indices of apoptosis after intermittent blood and crystalloid cardioplegia. Circulation (New York, N.Y.) , v. 30, p. I184-I189, 2005.

  • Feng, Jun ; Bianchi, Cesario ; Li, Jianyi ; Sellke, Frank W. . Bradykinin Preconditioning Preserves Coronary Microvascular Reactivity During Cardioplegia Reperfusion. The Annals of Thoracic Surgery , v. 79, p. 911-916, 2005.

  • Khan, Tanveer A. ; Bianchi, Cesario ; Voisine, Pierre ; Sandmeyer, Jennifer ; Feng, Jun ; Sellke, Frank W. . Aprotinin Inhibits Protease-Dependent Platelet Aggregation and Thrombosis. The Annals of Thoracic Surgery , v. 79, p. 1545-1550, 2005.

  • Voisine, Pierre ; Bianchi, Cesario ; Khan, Tanveer A. ; Ruel, Marc ; Xu, Shu-Hua ; Feng, Jun ; Li, Jian ; Malik, Tamer ; Rosinberg, Audrey ; Sellke, Frank W. . Normalization of coronary microvascular reactivity and improvement in myocardial perfusion by surgical vascular endothelial growth factor therapy combined with oral supplementation of l-arginine in a porcine model of endothelial dysfunction. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 129, p. 1414-1420, 2005.

  • Nakai, Yasunari ; Voisine, Pierre ; Bianchi, Cesario ; Xu, Shu-Hua ; Feng, Jun ; Malik, Tamer ; Rosinberg, Audrey ; Sellke, Frank W. . Effects of L-arginine on the endogenous angiogenic response in a model of hypercholesterolemia. Surgery , v. 138, p. 291-298, 2005.

  • FENG, J ; BIANCHI, C ; SANDMEYER, J. L. ; SELLKE, F. W. . Bradykinin preconditioning improves the profile of cell survival proteins and limits apoptosis after cardioplegic arrest. Circulation (New York, N.Y.) , v. 112, p. I190-I195, 2005.

  • Khan, Tanveer A. ; Bianchi, Cesario ; Ruel, Marc ; Voisine, Pierre ; Sellke, Frank W. . Mitogen-activated protein kinase pathways and cardiac surgery. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 127, p. 806-811, 2004.

  • Feng, Jun ; Bianchi, Cesario ; Li, Jianyi ; Sellke, Frank W . Improved profile of bad phosphorylation and caspase 3 activation after blood versus crystalloid cardioplegia. The Annals of Thoracic Surgery , v. 77, p. 1384-1389, 2004.

  • Voisine, Pierre ; Bianchi, Cesario ; Ruel, Marc ; Malik, Tamer ; Rosinberg, Audrey ; Feng, Jun ; Khan, Tanveer A. ; Xu, Shu-Hua ; Sandmeyer, Jennifer ; Laham, Roger J. ; Sellke, Frank W. . Inhibition of the cardiac angiogenic response to exogenous vascular endothelial growth factor. Surgery , v. 136, p. 407-415, 2004.

  • VOISINE, P ; RUEL, M ; KHAN, T. A. ; BIANCHI, C ; XU, S. H. ; KOHANE, I ; LIBERMANN, T. A. ; OTU, H ; SALTIEL, A. R. ; SELLKE, F. W. . Differences in gene expression profiles of diabetic and nondiabetic patients undergoing cardiopulmonary bypass and cardioplegic arrest. Circulation (New York, N.Y.) , v. 110, p. II280-II286, 2004.

  • RUEL, M. ; KHAN, T. A. ; VOISINE, P. ; BIANCHI, C. ; SELLKE, F. W. . Vasomotor dysfunction after cardiac surgery. European Journal of Cardio-Thoracic Surgery , v. 26, p. 1002-1014, 2004.

  • MALIK, T. A. ; BIANCHI, C. ; SELLKE, F. W. . Angiogenic gene therapy in the treatment of ischemic cardiovascular diseases. Gene Therapy & Molecular Biology , v. 8, p. 351-360, 2004.

  • Khan, Tanveer A. ; Bianchi, Cesario ; Voisine, Pierre ; Feng, Jun ; Baker, Jeralyn ; Hart, Melanie ; Takahashi, Minoru ; Stahl, Greg ; Sellke, Frank W. . Reduction of myocardial reperfusion injury by aprotinin after regional ischemia and cardioplegic arrest. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 128, p. 602-608, 2004.

  • KHAN, Tanveer A ; BIANCHI, C. ; ARAUJO, E. G. ; RUEL, Mark ; VOISINE, Peter ; SELLKE, Frank William . Activation of pulmonary mitogen-activated protein kinases during cardiopulmonary bypass. The Journal of Surgical Research (Print) , EUA, v. 115, n.1, p. 56-62, 2003.

  • KHAN, Tanveer A ; BIANCHI, C. ; ARAUJO, E. G. ; RUEL, Mark ; VOISINE, Peter ; LI, Jin ; LIDDICOAT, John R ; SELLKE, Frank William . Cardiopulmonary bypass reduces peripheral microvascular contractile function by inhibition of mitogen-activated protein kinase activity. Surgery , v. 2, n.134, p. 247-254, 2003.

  • RUEL, Mark ; BIANCHI, C. ; KHAN, Tanveer A ; XU, S. ; LIDDICOAT, John R ; VOISINE, Peter ; ARAUJO, E. G. ; KOHANE, I. S. ; LIBERMANN, T. A. ; SELLKE, Frank William . Gene expression profile after cardiopulmonary bypass and cardioplegic arrest. Journal of Thoracic and Cardiovascular Surgery (Print) , Philadelphia, EUA, v. 126, n.5, p. 1521-1530, 2003.

  • Ruel, Marc A ; Sellke, Frank W ; Bianchi, Cesario ; KHAN, Tanveer A ; Faro, Renato ; Zhang, Jian-Ping ; Cohn, William E . Endogenous myocardial angiogenesis and revascularization using a gastric submucosal patch. The Annals of Thoracic Surgery , v. 75, p. 1443-1449, 2003.

  • KHAN, Tanveer A ; Ruel, Marc ; Bianchi, Cesario ; Voisine, Pierre ; Komjáti, Katalin ; Szabo, Csaba ; Sellke, Frank W . Poly(ADP-ribose) polymerase inhibition improves postischemic myocardial function after cardioplegia-cardiopulmonary bypass. Journal of the American College of Surgeons , v. 197, p. 270-277, 2003.

  • RUEL, M ; WU, G. F. ; KHAN, T. A. ; VOISINE, P ; BIANCHI, C. ; LI, J. ; LI, J. ; Laham, R. J. ; SELLKE, F. W. . Inhibition of the cardiac angiogenic response to surgical FGF-2 therapy in a Swine endothelial dysfunction model. Circulation (New York, N.Y.) , v. 108, p. II335-II340, 2003.

  • KHAN, T. A. ; BIANCHI, C. ; RUEL, M. ; VOISINE, P. ; LI, J. ; LIDDICOAT, J. R. ; SELLKE, F. W. . Mitogen-activated protein kinase inhibition and cardioplegia-cardiopulmonary bypass reduce coronary myogenic tone. Circulation (New York, N.Y.) , v. 108, p. II348-II353, 2003.

  • Faro, Renato ; Toyoda, Yoshiya ; McCully, James D. ; Jagtap, Prakash ; Szabo, Eva ; Virag, Laszlo ; Bianchi, Cesario ; Levitsky, Sidney ; Szabo, Csaba ; Sellke, Frank W. . Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor. The Annals of Thoracic Surgery , v. 73, p. 575-581, 2002.

  • Bianchi, Cesario ; Wakiyama, Hidetaka ; Faro, Renato ; Khan, Tanveer ; McCully, James D ; Levitsky, Sidney ; Szabó, Csaba ; Sellke, Frank W . A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs. The Annals of Thoracic Surgery , v. 74, p. 1201-1207, 2002.

  • ARAUJO, E. G. ; BIANCHI, C. ; FARO, R. ; SELLKE, Frank William . Oscillation in the activities of MEK/ERK1/2 during cardiopulmonary bypass in pigs.. Surgery , EUA, v. 130, n.2, p. 182-191, 2001.

  • M tais, Caroline ; Bianchi, Cesario ; Li, Jianyi ; Simons, Michael ; Li, Jian ; Sellke, Frank W. . Serotonin-induced human coronary microvascular contraction during acute myocardial ischemia is blocked by COX-2 inhibition. Basic Research in Cardiology , v. 96, p. 59-67, 2001.

  • Araujo, Eugenio G. ; Bianchi, Cesario ; Sato, Kaori ; Faro, Renato ; Li, X.Alec ; Sellke, Frank W. . Inactivation of the MEK/ERK pathway in the myocardium during cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery (Print) , v. 121, p. 773-781, 2001.

  • BIANCHI, C. ; ARAUJO, E. G. ; SATO, K. ; SELLKE, F. W. . Biochemical and structural evidence for pig myocardium adherens junction disruption by cardiopulmonary bypass. Circulation (New York, N.Y.) , v. 104, p. I319-I-324, 2001.

  • Li, X.Alec ; Bianchi, Cesario ; Sellke, Frank W. . Rat Aortic Smooth Muscle Cell Density Affects Activation of MAP Kinase and Akt by Menadione and PDGF Homodimer BB. The Journal of Surgical Research (Print) , v. 100, p. 197-204, 2001.

  • Tofukuji, Motohisa ; Stahl, Gregory L ; Metais, Caroline ; Tomita, Mikio ; Agah, Azin ; Bianchi, Cesario ; Fink, Mitchell P ; Sellke, Frank W . Mesenteric dysfunction after cardiopulmonary bypass: role of complement C5a. The Annals of Thoracic Surgery , v. 69, p. 799-807, 2000.

  • Sato, Kaori ; Li, Jianyi ; Metais, Caroline ; Bianchi, Cesario ; Sellke, Frank . Increased Pulmonary Vascular Contraction to Serotonin after Cardiopulmonary Bypass: Role of Cyclooxygenase. The Journal of Surgical Research (Print) , v. 90, p. 138-143, 2000.

  • BIANCHI, C. ; SELLKE, F. W. . COS Cells Expression Cloning of Tyrosine-phosphorylated Proteins by Immunocytochemistry. Journal of Histochemistry and Cytochemistry , v. 48, p. 1097-1101, 2000.

  • BIANCHI, C . Receptor-Type Protein-Tyrosine Phosphatase μ Is Expressed in Specific Vascular Endothelial Bedsin Vivo. Experimental Cell Research , v. 248, p. 329-338, 1999.

  • Wilson III, D. M. ; BIANCHI, C. . Improved Immunodetection of Nuclear Antigens After Sodium Dodecyl Sulfate Treatment of Formaldehyde-fixed Cells. Journal of Histochemistry and Cytochemistry , v. 47, p. 1095-1100, 1999.

  • Reed, Guy L ; Houng, Aiilyan K ; Bianchi, Cesario . Comparative biochemical and ultrastructural studies of P-selectin in rabbit platelets. Comparative Biochemistry and Physiology. Part B: Biochemistry & Molecular Biology (Print) , v. 119, p. 729-738, 1998.

  • Campan, Michel ; Yoshizumi, Masao ; Seidah, Nabil G. ; Lee, Mu-En ; Bianchi, Cesario ; Haber, Edgar . Increased Proteolytic Processing of Protein Tyrosine Phosphatase μ in Confluent Vascular Endothelial Cells:  The Role of PC5, a Member of the Subtilisin Family. Biochemistry (Easton) , v. 35, p. 3797-3802, 1996.

  • Narula, J. ; Petrov, A. ; BIANCHI, C. ; Ditlow, C. C. ; Lister, B. C. ; Dilley, J. ; Pieslak, I. ; Chen, F. W. ; Torchilin, V. P. ; Khaw, B.-A. . Noninvasive Localization of Experimental Atherosclerotic Lesions With Mouse/Human Chimeric Z2D3 F(ab')2 Specific for the Proliferating Smooth Muscle Cells of Human Atheroma : Imaging With Conventional and Negative Charge Modified Antibody Fragments. Circulation (Online) , v. 92, p. 474-484, 1995.

  • Hancock, Wayne W. ; Shi, Chengwei ; Picard, Michael H. ; Bianchi, Cesario ; Russell, Mary E. . LEW-TO-F344 CAROTID ARTERY ALLOGRAFTS. Transplantation , v. 60, p. 1565-1572, 1995.

  • Shi, C. ; Russell, M. E. ; BIANCHI, C. ; Newell, J. B. ; Haber, E. . Murine model of accelerated transplant arteriosclerosis. Circulation Research , v. 75, p. 199-207, 1994.

  • Guillaume, Jean-Luc ; Petitjean, Francoise ; Haasemann, Martina ; Bianchi, Cesario ; Eshdat, Yuval ; Strosberg, A. Donny . Antibodies for the Immunochemistry of the Human beta3-Adrenergic Receptor. European Journal of Biochemistry (Print) (Cessou em 2004. Cont. ISSN 1742-464X The FEBS Journal (Print)) , v. 224, p. 761-770, 1994.

  • Kiuchi, K ; Shannon, R P ; Komamura, K ; Cohen, D J ; BIANCHI, C ; Homcy, C J ; Vatner, S F ; Vatner, D E . Myocardial beta-adrenergic receptor function during the development of pacing-induced heart failure.. The Journal of Clinical Investigation , v. 91, p. 907-914, 1993.

  • KONRAD, E. M. ; BIANCHI, C ; THIBAULT, G. ; GARCIA, R. ; PELLETIER, S. ; GENEST, J. ; CANTIN, M. . Localization and characterization of binding sites for circulating and cerebroventricular atrial natriuretic factor in rat choroid plexus. Neuroendocrinology (Basel) , v. 51, p. 304-314, 1990.

  • ISHIKAWA, Y. ; BIANCHI, C. ; NADAL-GINARD, B. ; HOMCY, C. J. . Alternative promoter and 5' exon generate a novel Gs alpha mRNA. The Journal of Biological Chemistry (Print) , v. 265, p. 8458-8462, 1990.

  • BIANCHI, C. ; THIBAULT, G. ; DELEAN, A. ; GENEST, J. ; CANTIN, M. . Atrial natriuretic factor binding sites in the jejunum. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY , v. 256, p. G436-G441, 1989.

  • BIANCHI, C. ; THIBAULT, G. ; WROBEL-KONRAD, E. ; DELEAN, A. ; GENEST, J. ; CANTIN, M. . Atrial natriuretic factor binding sites in experimental congestive heart failure. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY , v. 257, p. F515-F523, 1989.

  • BIANCHI, C. ; GUTKOWSKA, J. ; GARCIA, R. ; THIBAULT, G. ; GENEST, J. ; CANTIN, M. . Localization of 125I-atrial natriuretic factor (ANF)-binding sites in rat renal medulla. A light and electron microscope autoradiographic study. The Journal of Histochemistry and Cytochemistry , v. 35, p. 149-153, 1987.

  • BIANCHI, C. ; GUTKOWSKA, J. ; DELEAN, A. ; BALLAK, M. ; ANAND-SRIVASTAVA, M. B. ; GENEST, J. ; CANTIN, M. . Fate of [125I]angiotensin II in adrenal zona glomerulosa cells. Endocrinology (Philadelphia) , v. 118, p. 2605-2607, 1986.

  • BIANCHI, C. ; ANAND-SRIVASTAVA, M. B. ; DELEAN, A. ; GUTKOWSKA, J. ; FORTHOMME, D. ; GENEST, J. ; CANTIN, M. . Localization and characterization of specific receptors for atrial natriuretic factor in the ciliary processes of the eye. Current Eye Research (Print) , v. 5, p. 283-293, 1986.

  • BIANCHI, C. ; GUTKOWSKA, J. ; BALLAK, M. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. ; CANTIN, M. . Radioautographic localization of 125I-atrial natriuretic factor binding sites in the brain.. Neuroendocrinology (Basel) , v. 44, p. 365-372, 1986.

  • BIANCHI, C. ; GUTKOWSKA, J. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. ; CANTIN, M. . Distinct localization of atrial natriuretic factor and angiotensin II binding sites in the glomerulus. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY , v. 251, p. F594-F602, 1986.

  • BIANCHI, C. ; GUTKOWSKA, J. ; CHARBONNEAU, C. ; BALLAK, M. ; ANAND-SRIVASTAVA, M. B. ; DELEAN, A. ; GENEST, J. ; CANTIN, M. . Internalization and lysosomal association of [125I]angiotensin II in norepinephrine-containing cells of the rat adrenal medulla. Endocrinology (Philadelphia) , v. 119, p. 1873-1875, 1986.

  • GARAY, R. ; HANNAERT, P. ; RODRIGUE, F. ; DUNHAM, B. ; MARCHE, P. ; GENEST, J. ; BRAQUET, P. ; BIANCHI, C. ; CANTIN, M. ; MEYER, P. . Atrial natriuretic factor inhibits Ca(2+)-dependent K+ fluxes in cultured vascular smooth muscle cells. Journal of Hypertension. Supplement , v. 3, p. 297-298, 1985.

  • Bianchi, C. ; GUTKOWSKA, J. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. ; CANTIN, M. . Radioautographic localization of125I-atrial natriuretic fator (ANF) in rat tissues. Histochemistry , v. 82, p. 441-452, 1985.

  • DEUEL, T. F. ; BIANCHI, C. ; CANTLEY, L. . Restenosis Injury, a Problem in Regulation of Growth. In: Kenneth R. Chien. (Org.). Molecular Basis of Cardiovascular Disease: A Companion to Braunwald's Heart Disease. 2nded.: Saunders, 1998, v. , p. 367-391.

  • Bianchi, C. ; OLIVEIRA, P. S. ; Lassaletta, Antonio D. ; SELLKE, F. W. ; Kleber Gomes Franchini ; Schorl C . Rapamycin Treatment Regulates miRNAs Associated With Mtochodrial and Endoplasmic Reticulum Functions in a Pig Model of Myocardial Ischemia-reperfusion Injury. In: American Heart Association National Meeting 2015, 2015, Orlando. Circulation, 2015. v. 132. p. A19375-A19375.

  • Feng, J. ; Liu, Y. ; Singh, A. K. ; Dobrilovic, N. ; Chu, L. M. ; Clements, R. T. ; Bianchi, C. ; Selke, F. W. . Changes in Microvascular Reactivity after Cardiopulmonary Bypass in Patients with Uncontrolled versus Controlled Diabetes. In: AHA Council Lectures 2011, 2011. AHA Council Lectures 2011, 2011. v. 124.

  • Carreira M ; BIANCHI, C ; BATISTA JÚNIOR, MIGUEL LUIZ . Análise dos efeitos caquexia associada ao câncer em células cardíacas.. In: XX congresso de Iniciação Cientifica da Universidade de Mogi das Cruzes, 2017, Mogi das Cruzes. XX congresso de Iniciação Cientifica da Universidade de Mogi das Cruzes, 2017.

  • FENG, J ; DOBROLOVIC, N. ; Singh, A. K. ; BIANCHI, C ; SELLKE, F. W. . Differential Impairment of Adherence-Junction Expression/Phosphorylation of Human Myocardium in the Setting of Diabetes After Cardioplegia. In: American Heart Association National Meeting, 2013, Dallas. Circulation Supplement, 2013.

  • Shafique, Ehtesham ; Choy, Wing C ; Liu, Y. ; FENG, J ; BIANCHI, C ; Benjamin, Laura E ; SELLKE, F. W. ; ABID, R. . Oxidative Stress Improves Coronary Endothelial Function Through Activation of the Pro-Survival Kinase AMPK. In: American Heart Association National Meeting, 2013, Dallas, TX. Circulation Supplement, 2013.

  • Chu, L. M. ; Robich, M. P. ; FENG, J ; Oyamada, S. ; BIANCHI, C ; SELLKE, F. W. . Is hyperglycemia bad for the heart during acute ischemia?. In: American Association of Thoracic Surgeons, 2012. Journal of Thoracic and Cardiovascular Surgery, 2012. v. 143. p. 254.

  • CLEMENTS, R. T. ; Cordeiro, B. ; FENG, J ; BIANCHI, C ; SELLKE, F. W. . Inhibition of Large Conductance K+ Channels (BKCa) Improves Cardiac Functional Recovery Following Cold Hyperkalemic Cardioplegic (CP) Arrest in Isolated Hearts. In: American Heart Association National Meeting, 2011, Orlando, FL. Circulation Supplement, 2011. v. 124. p. A16926.

  • LASSALETTA, ANTONIO D ; Chu, L. M. ; SELLKE, F. W. ; BIANCHI, C . Rapamycin Increases Infarct Size and is Detrimental During Acute Ischemia-Reperfusion. In: American Heart Association National Meeting, 2011, Orlando, FL. Circulation Supplement, 2011. v. 124. p. A17106.

  • Zanetti, Arthus V D ; SANTOS, L. C. ; SCHOEPS, V. A. ; SANZOVO, P. S. ; CARNIELLO, J. V. S. ; MANSO, A. A. S. ; SELLKE, F. W. ; BIANCHI, C . Rapamycin-Regulated Ubiquitin Specific Peptidases Expression in Cardiocytes. In: FEDERATION AMER SOC EXP BIOL, 2011, Boston. FEDERATION PROCEEDINGS, 2013. v. 27. p. 1089.4.

  • CLEMENTS, R. T. ; Ivanov, A. R. ; Smejkal, G. ; FREEMAN, E. ; Bianchi, Cesario F. ; SELLKE, F. W. . Proteomic profile of patients before and after cardioplegia and cardiopulmonary bypass reveals specific changes to numerous metabolic and cytoskeletal proteins. In: FEDERATION AMER SOC EXP BIOL, 2011. FASEB Journal, 2011. v. 25. p. 1097.23.

  • Robich, M. P. ; Osipov, R. ; Chu, L. M. ; CHAUDARY, M. ; Coady, M. A. ; BIANCHI, C ; SELLKE, F. W. . Resveratrol Improves Cardiovascular Risk Factors and Myocardial Blood Flow in a Swine Model of Metabolic Syndrome and Chronic Myocardial Ischemia. In: 50th American Heart Association Cardiovascular Disease Epidemiology and Prevention and Nutrition, Physical Activity and Metabolism, 2010, San Francisco, CA. Circulation Supplement, 2010.

  • BIANCHI, C ; Chu, L. M. ; Osipov, R. ; Oyamada, S. ; IGNE-BIANCHI, J. ; Robich, M. P. ; SELLKE, F. W. . Myocardial Ischemia-Reperfusion Transcriptional Program in Normal and High Fat Diet. In: 90th American Association of Thoracic Surgeons, 2010, Toronto, CAN. American Association of Thoracic Surgeons Annual Meeting, 2010.

  • Robich, M. P. ; Chu, L. M. ; FENG, J ; BIANCHI, C ; Laham, R. J. ; Coady, M. A. ; SELLKE, F. W. . Effects of Nonselective COX and Selective COX-2 inhibition on collateral development in the Heart. In: 90th American Association of Thoracic Surgeons, 2010, Toronto, CAN. American Association of Thoracic Surgeons Annual Meeting, 2010.

  • Oyamada, S. ; MA, X. ; Robich, M. P. ; BIANCHI, C ; SELLKE, F. W. ; Laham, R. J. . Trans-Iliac Rat Aorta Stenting Model: A Novel High Throughput Preclinical Stent Model for Restenosis and Thrombosis.. In: American College of Cardiology, 2010. American College of Cardiology Conference Annual Meeting, 2010. v. 55. p. A117.E1097.

  • Oyamada, S. ; MA, X. ; Wu, Tim ; Robich, M. P. ; Bianchi, C. ; SELLKE, F. W. ; Laham, R. J. . In Vivo Biocompatibility Comparison Between Novel Biodegradable Polymer and Existing Non-Biodegradable Polymer Coated Stents. In: American College of Cardiology Conference, 2010. American College of Cardiology Conference Annual Meeting, 2010. v. 55. p. 0122.E1140.

  • BIANCHI, C ; Osipov, R. ; Oyamada, S. ; Chu, L. M. ; IGNE-BIANCHI, J. ; Sheller, M. R. ; SELLKE, F. W. . Porcine Myocardial Gene Expression Response to an Intravenous Infusion of the Thrombin Fragment TP 508 Is Modified by High-Cholesterol Diet in both Normal and Ischemic Areas. In: Arteriosclerosis, Thrombosis and Vascular Biology 2010 Scientific Sessions, 2010. Arteriosclerosis, Thrombosis and Vascular Biology 2010 Scientific Sessions, 2010.

  • CLEMENTS, R. T. ; FENG, J. ; BIANCHI, C ; SELLKE, F. W. . Inhibition of PKC-delta Increases Cardiac Contractile Performance and Coronary Perfusion following Cold Cardioplegic Arrest in Isolated Hearts. In: American Heart Association National Meeting, 2010. Circulation Supplement, 2010. v. 122. p. A19226.

  • Chu, L. M. ; Robich, M. P. ; BIANCHI, C ; Burgess, T. ; FENG, J ; Oyamada, S. ; SELLKE, F. W. . Non-selective and selective cyclooxygenase inhibition improve cardiovascular function in a hypercholesterolemic swine model of chronic ischemia. In: American Heart Association National Meeting, 2010. Circulation Supplement, 2010. v. 122. p. A20679.

  • CLEMENTS, R. T. ; Ivanov, A. R. ; Smejkal, G. ; BIANCHI, C ; SELLKE, F. W. . Phosphoproteomic profile of differentially phosphorylated proteins in human myocardium before and after cardiac surgery utilizing cardioplegia and cardiopulmonary bypass. In: FEDERATION AMER SOC EXP BIOL, 2010. FEDERATION PROCEEDINGS, 2010.

  • Robich, M. P. ; Chu, L. M. ; Coady, M. A. ; BIANCHI, C ; SELLKE, F. W. . Anti-Angiogenic Effect of Resveratrol in a Swine Model of Chronic Myocardial Ischemia and Hypercholesterolemia: Role of Angiostatin and VE-Cadherin. In: Association for Academic Surgery, 2010. Journal of Surgical Research, 2010. v. 158. p. 306.

  • Robich, M. P. ; Chu, L. M. ; Burgess, T. ; FENG, J ; BIANCHI, C ; SELLKE, F. W. . Effects of selective cyclooxygenase-2 and non-selective COX inhibition on myocardial function and perfusion. In: American College of Surgeons, 2010. Journal of the American College of Surgeons, 2010. v. 210. p. S33.

  • Robich, M. P. ; Chu, L. M. ; Matyal, Robina ; Laham, R. J. ; HOUT, M. ; KHABBAZ, K ; Bianchi, C. ; Coady, M. A. ; SELLKE, F. W. . Statins reduce molecular markers of angiogenesis in patients.. In: American College of Surgeons, 2010. Journal of the American College of Surgeons, 2010. v. 211. p. S33.

  • Chu, L. M. ; Robich, M. P. ; FENG, J ; Oyamada, S. ; BIANCHI, C ; SELLKE, F. W. . Hyperglycemia is protective against acute ischemia in a porcine model of type 1 diabetes. In: American Association of Thoracic Surgeons, 2010. Journal of Thoracic and Cardiovascular Surgery, 2010. v. 211. p. S28.

  • Chu, L. M. ; RAMLAWI, B ; BIANCHI, C ; SELLKE, F. W. . Gene expression profiles in neurocognitive decline after cardiopulmonary bypass implicate protein ubiquitination and oxidative phosphorylation pathways. In: American College of Surgeons, 2010. Journal of the American College of Surgeons, 2010. v. 211. p. S29.

  • PERRY, T. E. ; RAMLAWI, B ; BIANCHI, C ; MUEHLSCHLEGEL, J. D. ; SHERNAN, S. K. ; BODY, S. C. ; SELLKE, F. W. . New-Onset Postoperative Atrial Fibrillation Associated with Differential Peripheral Leukocyte Expression Pathways. In: American College of Cardiology Conference Annual Meeting, 2009. American College of Cardiology Conference (ACC) Annual Meeting, 2009.

  • Osipov, R. ; Robich, M. P. ; Chu, L. M. ; Oyamada, S. ; Liu, Y. ; FENG, J ; CLEMENTS, R. T. ; SHINBAUM, D. B. ; Bianchi, C. ; SELLKE, F. W. . Thrombin Fragment (TP508) Protects Myocardium in the Setting of Acute Ischemia-reperfusion Injury in Diabetic Pigs. In: American Heart Association National Meeting, 2009, Orlando, FL. Circulation Supplement, 2009.

  • FENG, J ; Robich, M. P. ; KHABBAZ, K ; Hagberg, Robert ; CLEMENTS, R. T. ; Osipov, R. ; BIANCHI, C ; SELLKE, F. W. . Impaired Contractile Response of Human Peripheral Arterioles to Endothelin-1 After Cardiopulmonary Bypass Arrest. In: American Heart Association National Meeting, 2009. Circulation Supplement, 2009.

  • Clements, R. T. ; FENG, J ; Bianchi, C. ; SELLKE, F. W. . Role of p38-MAPK and Small Heat Shock Protein 27 (HSP27) Phosphorylation in Regulation of Myocardial Function Following Cardioplegic Arrest. In: American Heart Association National Meeting, 2009. Circulation Supplement, 2009.

  • RAMLAWI, B ; OTU, H ; EMANI, S. ; BIANCHI, C ; SELLKE, F. W. . Tissue permeability associated with chemokine-class inflammatory response following cardiac surgery. In: American College of Surgeons Clinical Congress, 2009. Journal of the American College of Surgeons, 2009. v. 209. p. S29-S30.

  • Robich, M. P. ; Liu, Y. ; FENG, J ; Osipov, R. M. ; CLEMENTS, R. T. ; BIANCHI, C ; SELLKE, F. W. . Serotonin-induced coronary microvessel contractions post cardioplegia, cardiopulmonary bypass are mediated in part via the phospholipase A2 pathway in patients. In: American College of Surgeons, 2009. Journal of the American College of Surgeons, 2009. v. 209. p. S27.

  • Robich, M. P. ; Osipov, R. M. ; FENG, J ; Liu, Y. ; CLEMENTS, R. T. ; BIANCHI, C ; SELLKE, F. W. . Time-dependent differential expression of angiogenic markers in a swine model of chronic myocardial ischemia. In: American College of Surgeons Clinical Congress, 2009. Journal of the American College of Surgeons, 2009. v. 209. p. S27-S8.

  • SODHA, N. R. ; Osipov, R. M. ; CLEMENTS, R. T. ; Xu, S.-H. ; BIANCHI, C ; SELLKE, F. W. . Myocardial antiangiogenic enzymatic activity is increased in the setting of diabetes mellitus type 2. In: American College of Surgeons, 2009. Journal of the American College of Surgeons, 2009. v. 209. p. S27.

  • Osipov, R. M. ; Robich, M. P. ; FENG, J ; Liu, Y. ; Oyamada, S. ; Clements, R. T. ; Bianchi, C. ; Wagstaff, J. ; SELLKE, F. W. . Thrombin fragment (TP 508) protects myocardium during ischemia-reperfusion injury in the setting of hypercholesterolemia. In: American College of Surgeons Clinical Congress, 2009. Journal of the American College of Surgeons Supplement, 2009. v. 209. p. S28.

  • RAMLAWI, B ; OTU, H ; EMANI, S. ; BIANCHI, C ; SELLKE, F. W. . Aprotinin Attenuates Genomic Expression Variability Following Cardiac Surgery. In: American Association of Thoracic Surgeons, 2008, San Diego, CA. American Association of Thoracic Surgeons Annual Meeting, 2008.

  • Osipov, R. ; CLEMENTS, R. T. ; Xu, S.-H. ; Li, Jian ; BIANCHI, C ; SELLKE, F. W. . Myocardial Profile of Thrombospondin-1 in Porcine Model of Type I Diabetes. In: International Society for Minimally Invasive Cardiothoracic Surgery, 2008, Boston. International Society for Minimally Invasive Cardiothoracic Surgery 11th Annual Scientific Meeting, 2008.

  • Osipov, R. ; BIANCHI, C ; FENG, J ; Liu, Y. ; CLEMENTS, R. T. ; SODHA, N. R. ; SELLKE, F. W. . Effect of Hypercholesterolemia on Myocardial Necrosis and Apoptosis in Response to Ischemia-Reperfusion Injury. In: American Heart Association National Meeting, 2008, New Orleans. Circulation Supplement, 2008.

  • Clements, R. T. ; SODHA, N. R. ; Feng, J. ; BOODHWANI, M ; EMANI, S. ; BIANCHI, C ; SELLKE, F. W. . Type-I diabetic impairment of NO-dependent coronary smooth muscle relaxation correlates with enhanced contractile signaling and is normalized by insulin. In: FEDERATION AMER SOC EXP BIOL, 2007, Washington. FEDERATION PROCEEDINGS, 2007.

  • SODHA, N. R. ; CLEMENTS, R. T. ; FENG, J. ; SZABO, C. ; Bianchi, C. ; SELLKE, F. W. . Exogenous Sulfide Reduces Myocardial Apoptosis in Response to Ischemia-Reperfusion Injury. In: European Academy of Cardiothoracic Surgeons, 2007. European Academy of Cardiothoracic Surgeons, 2007.

  • SODHA, N. R. ; BOODHWANI, M. ; CLEMENTS, R. T. ; Xu, S.-H. ; BIANCHI, C ; SELLKE, F. W. . Angiostatin and Endostatin Expression Are Increased in the Skeletal Musculature of Diabetics. In: Annual Meeting of the New England Surgical Society, 2007. Annual Meeting of the New England Surgical Society, 2007.

  • SODHA, N. R. ; FENG, J. ; CLEMENTS, R. T. ; Bianchi, C. ; BOODHWANI, M. ; RAMLAWI, B. ; MIENO, S ; SELLKE, F. W. . Protein Kinase C Modulates Microvascular Reactivity in the Human Coronary and Skeletal Microcirculation. In: Society of University Surgeons, 2007. Society of University Surgeons, 2007.

  • EMANI, S. ; RAMLAWI, B ; SODHA, N. R. ; BIANCHI, C ; SELLKE, F. W. . Increased Length of Hospitalization and Weight Gain in Diabetic Patients are Associated with Induction of HIF1 Expression and Higher Serum Levels of Permeability-inducing Growth Factors: VEGF, and HGF. In: American Heart Association National Meeting, 2007. Circulation Supplement, 2007. p. 1559.

  • SODHA, N. R. ; CLEMENTS, R. T. ; FENG, J. ; BIANCHI, C ; SZABO, C. ; Stahl, Gregory L. ; SELLKE, F. W. . Exogenous Sulfide Limits Inflammation in Response to Myocardial Ischemia - Reperfusion Injury. In: American Heart Association National Meeting, 2007. Circulation Supplement, 2007. p. 2269.

  • RAMLAWI, B ; MIENO, S ; SODHA, N. R. ; Bianchi, C. ; CLEMENTS, R. T. ; FENG, J ; SELLKE, F. W. . Oxidative Stress Levels Associated to New Onset Atrial Fibrillation after Cardiac Surgery: A Case-Control Study. In: Society of Thoracic Surgeons, 2007. Society of Thoracic Surgeons Meeting, 2007.

  • CLEMENTS, R. T. ; SODHA, N. R. ; FENG, J. ; EMANI, S. ; Senthilnathan, V. ; KHABBAZ, K ; BIANCHI, C ; SELLKE, F. W. . Proteomic Profile of Differentially Regulated Proteins In Human Myocardium Before and After Cardiac Surgery Utilizing Cardioplegia and Cardiopulmonary. In: American Heart Association National Meeting, 2007. Circulation Supplement, 2007. p. 1575.

  • BOODHWANI, M ; VOISINE, P ; RUEL, M ; SODHA, N ; FENG, J ; Xu, S.-H. ; Bianchi, C. ; SELLKE, F. W. . Comparison of vascular endothelial growth factor and fibroblast growth factor-2 in a swine model of endothelial dysfunction. In: European Assoc. of Cardiothoracic Surgery, 2007. European Assoc. of Cardiothoracic Surgery Meeting, 2007.

  • CLEMENTS, R. T. ; SODHA, N. R. ; BOODHWANI, M ; FENG, J ; Bianchi, Cesario F. ; SELLKE, F. W. . Impaired smooth muscle regulation in diabetes is normalized by insulin and correlates with insulin dependent effects on MLC phosphorylation. In: FEDERATION AMER SOC EXP BIOL, 2007. FASEB Journal, 2007. v. 21. p. 959.7.

  • RAMLAWI, B ; OTU, H ; MIENO, S ; SODHA, N ; BIANCHI, C ; SELLKE, F. W. . Oxidative stress and postoperative atrial fibrillation after cardiac surgery. In: Canadian Society of Cardiology, 2007. Canadian Journal of Cardiology, 2007.

  • SODHA, N ; FENG, J ; CLEMENTS, R ; BIANCHI, C ; BOODHWANI, M ; RAMLAWI, B ; MIENO, S ; SELLKE, F. W. . Protein Kinase C alpha modulates microvascular reactivity in the human coronary and skeletal microcirculation. In: Association for Academic Surgery, 2007. Journal of Surgical Research, 2007. v. 137. p. 155.

  • RAMLAWI, B ; RUDOLPH, J. L. ; MIENO, S ; FENG, J ; BIANCHI, C ; KHABBAZ, K ; BOODHWANI, M ; KEVKOFF, S. E. ; MARCANTONIO, E. R. ; SELLKE, F. W. . Serologic Markers of Brain Injury Associated to Cognitive Function After Cardiopulmonary Bypass. In: American Surgical Association, 2006, Boston. American Surgical Association, 2006.

  • Clements, R. T. ; Feng, J. ; SODHA, N. R. ; RAMLAWI, B ; MIENO, S ; BOODHWANI, M ; Xu, S.-H. ; BIANCHI, C ; SELLKE, F. W. . Surgical Ischemia Induces Phosphorylation and Translocation of Heat Shock Protein 27 and aB-Crystallin in Human Myocardium. In: American Heart Association Council on Basic Cardiovascular Sciences - Translation of Basic Insights into Clinical Practice, 2006, Keystone, CO. Circulation Research, 2006.

  • RAMLAWI, B ; BIANCHI, C ; Laham, R. J. ; SODHA, N. R. ; BOODHWANI, M. ; KROSTING, J. ; PELTIER, H. ; SELLKE, F. W. . Lack of microRNA Regulation in Myocardial and Skeletal Muscle in Response to Cardioplegic Arrest and Cardiopulmonary Bypass. In: American Heart Association Council on Basic Cardiovascular Sciences - Translation of Basic Insights into Clinical Practice,, 2006, Keystone, CO. Circulation Research, 2006.

  • Clements, R. T. ; FENG, J ; SODHA, N. R. ; MIENO, S. ; RAMLAWI, B. ; BOODHWANI, M. ; Bianchi, C. ; SELLKE, F. W. . Cardioplegia and Cardiopulmonary Bypass Induces Phosphorylation and Myofilament Localization of Heat Shock Protein 27 and aB-Crystallin in Human Myocardium. In: American Heart Association National Meeting, 2006. Circulation Supplement, 2006.

  • MIENO, S ; BOODHWANI, M ; SODHA, N. R. ; CLEMENTS, R. T. ; RAMLAWI, B ; FENG, J ; BIANCHI, C ; SELLKE, F. W. . Effects of Diabetes Mellitus and Cryopreservation on Bone Marrow Derived Endothelial Progenitor Cells. In: American Heart Association National Meeting, 2006. Circulation Supplement, 2006.

  • KHABBAZ, K ; FENG, J ; BOODHWANI, M ; CLEMENTS, R. T. ; Bianchi, Cesario F. ; SELLKE, F. W. . Non-ischemic myocardial acidosis adversely affects microvascular and myocardial function and triggers apoptosis during cardioplegia. In: American Heart Association National Meeting, 2006. Circulation Supplement, 2006.

  • RAMLAWI, B ; FENG, J ; BIANCHI, C ; MIENO, S ; SELLKE, F. W. . Apoptosis Gene Expression and Activation During Cardiopulmonary Bypass.. In: American Federation for Clinical Research, 2006. Investigative Medicine, 2006. v. 54. p. s382-s3.

  • RAMLAWI, B ; KHAN, T. A. ; VOISINE, P ; BIANCHI, C ; BOODHWANI, M ; SELLKE, F. W. . Gene Expression Profiles Following Cardiac Surgery in Diabetic Patients and Their Clinical Correlation. In: American Federation for Clinical Research, 2006. Journal of Investigative Medicine, 2006. v. 54. p. S383.

  • RAMLAWI, B ; OTU, H ; KOHANE, I. S. ; BIANCHI, C ; SELLKE, F. W. . Genomic expression pathways associated to brain injury after cardiopulmonary bypass. In: American Heart Association National Meeting, 2006. Circulation Supplement, 2006.

  • SODHA, N. R. ; CLEMENTS, R ; FENG, J ; BOODHWANI, M ; RAMLAWI, B ; MIENO, S ; BIANCHI, C. ; SELLKE, F. W. . Cardiopulmonary bypass with cardioplegic arrest activates protein kinase C in the human myocardium. In: American College of Surgeons, 2006. Journal of the American College of Surgeons, 2006. v. 203. p. S22-S3.

  • FENG, J ; BIANCHI, C ; SELLKE, F. W. . Bradykinin induces microvascular preconditioning: role of PI3-kinase. In: International Society of Heart Failure / North America Section, 2005, New Orleans. International Society of Heart Failure / North America Section, 2005.

  • MALIK, T. A. ; BIANCHI, C ; SELLKE, F. W. . The Effect of Cardiopulmonary Bypass on Cell Junctions: Catenins, Cadherins and Connexins. In: American College of Cardiology, 2005, Orlando, FL. Annual Meeting of the American College of Cardiology, 2005. v. 45. p. 223A.

  • NAKAI, Y. ; VOISINE, P ; BIANCHI, C ; FENG, J ; MALIK, T. A. ; Rosinberg, Audrey ; SELLKE, F. W. . Effects of L-arginine on the Endogenenous Angiogenic Response in a Model of Hypercholesterolemia. In: Society of University Surgeons, 2005, Nasville. 66th Annual Meeting of the Society of University Surgeons, 2005.

  • RAMLAWI, B ; KHAN, T. A. ; RUEL, M ; VOISINE, P ; BIANCHI, C ; LIDDICOAT, J. R. ; BOODHWANI, M ; SELLKE, F. W. . Variations in gene expression profiles following cardiac surgery in diabetic patients and their clinical correlation. In: American College of Surgeons 91st Clinical Congress, 2005, San Francisco. Journal of the American College of Surgeons 91st Clinical Congress, 2005. v. 201. p. S41.

  • BOODHWANI, M ; NAKAI, Y. ; VOISINE, P ; Xu, S.-H. ; FENG, J ; BIANCHI, C ; NATHAN, S. ; RUEL, M ; SELLKE, F. W. . Atorvastatin alters myocardial expression of vascular endothelial growth factor and endostatin in hypercholesterolemic swine: Implications for angiogenesis. In: American College of Surgeons 91st Clinical Congress, 2005, San Francisco. Journal of the American College of Surgeons 91st Clinical Congress, 2005. v. 201. p. S26-S7.

  • RAMLAWI, B ; KHAN, T. A. ; VOISINE, P ; FENG, J ; Bianchi, C. ; LIDDICOAT, J. R. ; SELLKE, F. W. . Gene expression profiles following cardiac surgery and their correlation with clinical outcomes. In: Canadian Cardiovascular Society Meeting, 2005, Montreal. Canadian Cardiovascular Society Meeting, 2005.

  • RAMLAWI, B ; FENG, J ; BIANCHI, C ; MIENO, S ; KHABBAZ, K ; Xu, S.-H. ; SELLKE, F. W. . Apoptosis gene expression and activation during cardiopulmonary bypass. In: Canadian Cardiovascular Society Meeting, 2005, Montreal. Canadian Cardiovascular Society Meeting, 2005.

  • VOISINE, P ; BIANCHI, C ; RUEL, M ; Xu, S.-H. ; FENG, J ; Rosinberg, Audrey ; SELLKE, F . Growth factor based therapeutic angiogenesis n a model of endothelial dysfunction: Selective influence of L-arginine administration. In: Canadian Cardiovascular Society Meeting, 2005, Montreal. Canadian Cardiovascular Society Meeting, 2005.

  • VOISINE, P ; RUEL, M ; BIANCHI, C ; KHAN, T. A. ; FENG, J ; Li, Jian ; Laham, R. J. ; MALIK, T. ; SELLKE, F. W. . Inhibition of the Cardiac Angiogenic Response to Exogenous Vascular Endothelial Growth Factor (VEGF) Therapy in a Porcine Model of Endothelial Dysfunction. In: Society of University Surgeons, 2005, St-Louis, MO. Society of University Surgeons Meeting, 2005.

  • BOODHWANI, M ; VOISINE, P ; FENG, J ; Xu, S.-H. ; Li, Jian ; MIENO, S ; RAMLAWI, B ; BIANCHI, C ; Laham, R. J. ; SELLKE, F. W. . Atorvastatin impairs myocardial angiogenic response to chronic ischemia in normocholesterolemic swine. In: American Heart Association National Meeting, 2005. Circulation Supplement, 2005.

  • MALIK, T. ; DONNELL-FINK, L. ; BIANCHI, C ; FOGLER, R. ; SELLKE, F. W. . Effect of aging on the cardioplegia-induced change in growth factor response. In: American Heart Association National Meeting, 2005. Circulation Research, 2005.

  • VOISINE, P ; Li, Jian ; Li, Jianyi ; Bianchi, C. ; KHAN, T. A. ; RUEL, M ; Xu, S.-H. ; Feng, J. ; Rosinberg, Audrey ; MALIK, T. ; NAKAI, Y. ; SELLKE, F. W. . L-Arginine Supplementation Improves the Inhibited Angiogenic Response to FGF in a Porcine Model of Myocardial Ischemia with Endothelial Dysfunction. In: American Heart Association National Meeting, 2004. Circulation Supplement, 2004. v. 110. p. II398.

  • KHAN, T. A. ; VOISINE, P ; BIANCHI, C ; Rosinberg, Audrey ; FENG, J ; MALIK, T. A. ; SELLKE, F. W. . Aprotinin preserves coronary endothelial cellular junctions and reduces myocardial edema after regional ischemia and cardioplegic arrest. In: American Heart Association National Meeting, 2004. Circulation Supplement, 2004. v. 110. p. III506.

  • FENG, J ; Bianchi, C. ; SANDMEYER, J. L. ; SELLKE, F. W. . Preconditioning Improves the Profile of Bad Phosphorylation and Caspase-3 Activation after Cardioplegic Arrest. In: American Heart Association National Meeting, 2004. Circulation Supplement, 2004. v. 110. p. III358.

  • Feng, J. ; BIANCHI, C ; SANDMEYER, J. L. ; SELLKE, F. W. . Molecular Indices of Apoptosis after Intermittent Blood and Crystalloid Cardioplegia. In: American Heart Association National Meeting, 2004. Circulation Supplement, 2004. v. 110. p. III753.

  • VOISINE, P ; RUEL, M ; KHAN, T. A. ; Bianchi, C. ; Xu, S.-H. ; KOHANE, I ; LIBERMANN, T. A. ; SELLKE, F. W. . Gene Expression Profile in Diabetic Patients After Cardiopulmonary Bypass and Cardioplegic Arrest. In: Canadian Society of Cardiology, 2003. Canadian Journal of Cardiology, 2003. v. 19. p. 145A.

  • VOISINE, P ; RUEL, M ; Bianchi, C. ; KHAN, T. A. ; Xu, Shu-Hua ; FENG, J ; Laham, R. J. ; SELLKE, F. W. . Hypercholesterolemia-Induced Resistance to Exogenous FGF-2 Effects on Endothelial Function in a Swine Model of Chronic Myocardial Ischemia. In: Canadian Society of Cardiology, 2003. Canadian Journal of Cardiology, 2003. v. 19. p. 158A.

  • VOISINE, P ; YADLAPALLI, N. ; Khan, Tanveer A. ; Laham, R. J. ; ROY-CHAUDHURY, P. ; BURNETT, S. K. ; Bianchi, C. ; SELLKE, F. W. ; SUKHATME, V. P. . Expression of a Platelet-Derived Growth Factor (PDGF)-Signaling Pathway in a Porcine Model of Arterio-Venous (AV) Graft Stenosis. In: Canadian Society of Cardiology, 2003. Canadian Journal of Cardiology, 2003. v. 19. p. 183A.

  • KHAN, T. A. ; VOISINE, P ; RUEL, M ; BIANCHI, C ; FENG, J ; Xu, Shu-Hua ; Li, Jianyi ; SELLKE, F. W. . Role of Heparan Sulfate in Enhanced Coronary Microvascular Relaxation Due to Chronic Myocardial Ischemia.. In: American Heart Association National Meeting, 2003. Circulation Supplement, 2003. v. 108. p. IV-225.

  • VOISINE, P ; RUEL, M ; KHAN, T. A. ; Bianchi, C. ; Xu, S.-H. ; KOHANE, I ; LIBERMANN, T. A. ; SELLKE, F. W. . Differences in Gene Expression Profiles of Diabetic and Non-diabetic Patients Undergoing Cardiopulmonary Bypass and Cardioplegic Arrest. In: American Heart Association National Meeting, 2003. Circulation Supplement, 2003. v. 108. p. IV-510.

  • VOISINE, P ; RUEL, M ; Bianchi, C. ; KHAN, T. A. ; Xu, S.-H. ; FENG, J ; Laham, R. J. ; SELLKE, F. W. . Chronic Hypercholesterolemia Induces Resistance to the Exogenous Effects of FGF-2 on Endothelial Function in a Swine Model of Chronic Myocardial Ischemia. In: American Heart Association National Meeting, 2003. Circulation Supplement, 2003. v. 108. p. IV-298.

  • Khan, Tanveer A. ; Bianchi, C. ; RUEL, M ; LIDDICOAT, J. R. ; Li, Jianyi ; SELLKE, F. W. . Mitogen-activated protein kinase and cardiopulmonary bypass reduce coronary myogenic tone. In: American Heart Association National Meeting, 2002. Circulation Supplement, 2002. p. 1630.

  • Ruel, Marc ; Bianchi, C. ; KHAN, T. A. ; Xu, Shu-Hua ; Cohn, William E ; LIDDICOAT, John R ; LYON, H. ; LIBERMANN, T. A. ; KOHANE, I ; SELLKE, F. W. . Genomic expression profile of the clinical response to cardiopulmonary bypass. In: American Heart Association National Meeting, 2002. Circulation Supplement, 2002. p. 1873.

  • Ruel, Marc ; WU, G. F. ; Khan, Tanveer A. ; BIANCHI, C ; Cohn, William E ; Laham, R. J. ; SELLKE, F. W. . Inhibited angiogenesis response to surgical FGF-2 protein therapy in a swine model of endothelial dysfunction. In: American Heart Association National Meeting, 2002. Circulation Supplement, 2002. p. 1633.

  • FARO, R. ; Toyoda, Yoshiya ; McCully, James D ; BIANCHI, C ; SZABO, C. ; SELLKE, F. W. . Inhibition of Poly ADP-ribose synthetase by PJ-34 reduces pig heart infarct size and improves post-ischemic functional recovery. In: Molecular, Integrative, and Clinical Approaches to Myocardial Ischemia, 2001. Molecular, Integrative, and Clinical Approaches to Myocardial Ischemia, 2001. p. P80.

  • FARO, R. ; Wakiyama, Hidetaka ; McCully, James D ; Bianchi, C. ; SZABO, C. ; SELLKE, F. W. . Reduction in pig heart infarct size induced by novel peroxinitrite decomposition catalyst (FP-15). In: Molecular, Integrative, and Clinical Approaches to Myocardial Ischemia, 2001. Molecular, Integrative, and Clinical Approaches to Myocardial Ischemia, 2001. p. P83.

  • Bianchi, C. ; Khan, Tanveer A. ; RUEL, M. ; Li, Jian ; Cohn, William E ; LIDDICOAT, John R ; SELLKE, F. W. . Mitogen-activated protein kinase activation and vasomotor dysfunction after cardiopulmonary bypass. In: The Myogenic Centennial Conference, 2001, Stow, VT, USA. The Myogenic Centennial Conference, 2001.

  • Ruel, Marc ; Bianchi, C. ; Zhang, Jian-Ping ; SELLKE, F. W. ; Cohn, William E . Myocardial Revascularization with a GEA-based Gastric Submucosal Patch. In: American Heart Association National Meeting, 2001. Circulation Supplement, 2001. p. 1926.

  • ARAUJO, E. G. ; BIANCHI, C ; SATO, K. ; SELLKE, F. W. . Changes in activities of 42/44 map kinases by cardiopulmonary bypass. In: American College of Surgeons, 2001. Journal of the American College of Surgeons, 2001. v. 191. p. S75.

  • BIANCHI, C ; ARAUJO, E. G. ; SATO, K. ; SELLKE, F. W. . Biochemical and Structural Evidence for Pig Myocardium Adherens Junction Disruption by Cardiopulmonary Bypass. In: American Heart Association National Meeting, 2001. Circulation Supplement, 2001. v. 104. p. I319.

  • Araujo, Eugenio G. ; Bianchi, C. ; SATO, K. ; Xu, Shu-Hua ; FRANKLIN, A. ; SELLKE, F. W. . Biochemical and Structural Evidence fro Pig Myocardium Adherens Junctions Disruption by Cardiopulmonary Bypass. In: American Heart Association National Meeting, 2000. Circulation Supplement, 2000. p. 2814.

  • Bianchi, C. . Characterization of Receptor-Type Tyrosine Phosphatase mu expression in Rats. Dynamic of Disassembly in Vascular Endothelium(VE) Cell-Cell Contacts. In: FEDERATION AMER SOC EXP BIOL, 1997. FEDERATION PROCEEDINGS, 1997. v. 11. p. A457.

  • Bianchi, C. . Menadione-induced Oxidative Stress Potentiate PDGF BB Activation of MAPK in Rat Aorta Smooth Muscle Cells. A Cross Talk Between Oxidant and Peptide Growth Factor Signal Transduction. In: American Heart Association National Meeting, 1996. Circulation Supplement, 1996. v. 94. p. I638.

  • UTANS, U. ; ARCECI, R. J. ; YAMASHITA, Y. ; Bianchi, C. ; RUSSELL, M. E. . Upregulation of a novel macrophage gene, Allograft Inflamatory Factor-1, in rat models of chronic cardiac rejection and balloon injury of the carotid artery. In: American Heart Association National Meeting, 1994. Circulation Supplement, 1994. v. 90. p. I572.

  • Campan, Michel ; ZHANG, D. ; Bianchi, C. . Superoxide-mediated protein tyrosine phosphorylation in rat aortic smooth muscle cells (RASMC): Possible signal transduction pathway for oxidative stress.. In: American Heart Association National Meeting, 1993, New Orleans. Circulation Supplement, 1993. v. 88. p. i333.

  • REED, G. L. ; Bianchi, C. ; HOUNG, A. K. . Characterization of APP: A protein expressed on the platelet membrane after cellular activation. In: American Heart Association National Meeting, 1993, New Orleans. Circulation Supplement, 1993. v. 88. p. I457.

  • HOLMER, S. R. ; SUSANNI, E. E. ; Bianchi, C. ; IM, M. ; HALNON, N. J. ; HOMCY, C. J. . Overexpression of the short form of Gsalpha increases basal adenylyl cyclase while decreasing stimulation by GTP-G-S. In: Clinical Research, 1990. Proceedings of the Federation for Clinical Research, 1990. p. 287A.

  • ISHIKAWA, Y. ; Bianchi, C. ; NADAL-GINARD, B. ; Homcy, C J . Alternative promoter and 5' exon generate novel Gsa mRNA. In: Clinical Research, 1990. FEDERATION PROCEEDINGS, 1990. p. 287A.

  • ISHIKAWA, Y. ; CHEN, L. ; Bianchi, C. ; HOMCY, C. J. . Characterization of the alternative promoters of the canine Gsalpha gene. In: American Heart Association National Meeting, 1990. Circulation Supplement, 1990. v. 82. p. 2128.

  • WROBEL-KONRAD, E. ; Bianchi, C. ; THIBAULT, G. ; CANTIN, M. . Ultrastructural localization of binding sites for blood and cerebrospinal fluid ANF in rat choroid plexus (CHP). In: FEDERATION AMER SOC EXP BIOL, 1989. FEDERATION PROCEEDINGS, 1989. v. 3. p. 4540.

  • Bianchi, C. ; GUTKOWSKA, J. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. ; CANTIN, M. . Atrial natriuretic factor binding sites in the rat jejunum. In: 4th International Congress on Cell Biology, 1988, Montreal. 4th International Congress on Cell Biology, 1988. p. 158A.

  • WROBEL-KONRAD, E. ; BIANCHI, C ; THIBAULT, G. ; GENEST, J. ; CANTIN, M. . Localization of atrial natriuretic factor binding sites in rat choroid plexus by light and electron microscopic autoradiography in vivo. In: Journee de la Recherche des Etudiants. Institute de Recherches Clinique de Montreal, 1988, Montreal. Journee de la Recherche des Etudiants. Institute de Recherches Clinique de Montreal, 1988. p. 20.

  • BIANCHI, C ; GRENIER, M. ; DURAND, L. G. ; GENEST, J. ; CANTIN, M. . Characterization of ANF binding sites in cardiomyopathic hamsters.. In: Journee de la Recherche des etudiants. Institut de Recherches Clinique de Montreal., 1988. Journee de la Recherche des etudiants. Institut de Recherches Clinique de Montreal., 1988. p. 21.

  • GRENIER, M. C. ; DEGHISE, J. ; BLANCHARD, M. ; Bianchi, C. ; DURAND, L. G. . Analyse d'images autoradiographiques par ordinateur. In: Association des etudiants aux Grades superieurs, Faculte de Medecine de l'Universite de Montreal, 1987, Montreal. Association des etudiants aux Grades superieurs, Faculte de Medecine de l'Universite de Montreal, 1987. v. 1987.

  • BIANCHI, C ; GUTKOWSKA, J. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. ; CANTIN, M. . LOCALIZATION OF TARGET-CELLS FOR ATRIAL-NATRIURETIC-FACTOR IN THE LUNG, LIVER AND SMALL-INTESTINE-AN INVIVO ELECTRON-MICROSCOPIC AUTORADIOGRAPHIC STUDY. In: Interamerican Society of Hypertension, 1987. Hypertension, 1987.

  • BIANCHI, C ; THIBAULT, G. ; GENEST, J. ; CANTIN, M. . Etude de la captation pulmonaire du facteur natriuretique des oreillettes chez le rat. In: IV Journee Scientifique du Departement de Pathologie de l'Universite de Montreal, 1987, Montreal. IV Journee Scientifique du Departement de Pathologie de l'Universite de Montreal, 1987. p. 4.

  • Bianchi, C. ; GUTKOWSKA, J. ; GENEST, J. ; CANTIN, M. . Ultrastructural localization of 125I-atrial natriuretic factor binding sites in the kidney. In: Cardiovascular Pharmacology Meeting, 1986. J Cardiovasc Pharmacol, 1986. v. 8. p. 1327.

  • GARAY, R. ; HANNAERT, P. ; RODRIGUE, F. ; MARCHE, P. ; DUNHAM, B. ; Bianchi, C. ; CANTIN, M. ; BRAQUET, P. . Atrial natriuretic factor (ANF) inhibits Ca-dependent K-fluxes in cultured vascular smooth muscle cells. In: Cardiovascular Pharmacology Meeting, 1986. J Cardiovasc Pharmacol, 1986. v. 8. p. 1290.

  • BIANCHI, C ; GUTKOWSKA, J. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. ; CANTIN, M. . Comparative localization and effect of atrial natriuretic factor (ANF) and angiotensin II (AII) on the glomerulus. An Ultrastrctural radioautographic and functional study. In: International Union of Physiological Sciences, 1986. Proceedings of the International Union of Physiological Sciences, 1986. v. 15. p. 424.

  • Bianchi, C. ; GUTKOWSKA, J. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. ; CANTIN, M. . Light and Electron microscopic radioautographic localization of 125I-Atrial Natriuretic Factor binding sites in the rat kidney. In: The Endocrine Society, 68th Annual Meeting, 1986. The Endocrine Society, 68th Annual Meeting, 1986. v. 536. p. 165.

  • BIANCHI, C ; GUTKOWSKA, J. ; GARCIA, R. ; THIBAULT, G. ; GENEST, J. ; CANTIN, M. . RENAL DISTRIBUTION OF I-125 ATRIAL-NATRIURETIC-FACTOR BINDING-SITES AS VISUALIZED BY ULTRASTRUCTURAL AUTORADIOGRAPHY. In: Interamerican Society of Hypertension, 1986. Hypertension, 1986.

  • BIANCHI, C ; GUTKOWSKA, J. ; GENEST, J. ; CANTIN, M. . Localization renale des sites de liaison du 125I-facteur natriuretic des oreillettes chez le rat.. In: III Journee Scientifique du departement de pathologie de l'Universite de Montreal, 1986, Montreal. III Journee Scientifique du departement de pathologie de l'Universite de Montreal, 1986. p. 2.

  • Bianchi, C. ; GUTKOWSKA, J. ; GENEST, J. ; CANTIN, M. . Localization of 125I-labeled atrial natriuretic factor in rat tissues.. In: FEDERATION AMER SOC EXP BIOL, 1985. FEDERATION PROCEEDINGS, 1985. v. 44. p. 512.

  • Bianchi, C. ; GUTKOWSKA, J. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. ; CANTIN, M. . 125I-atrial natriuretic factor receptors in rat tissues. An in vivo light microscopic radioautographic study. In: Interamerican Society of Hypertension, 1985, New York. Interamerican Society of Hypertension, 1985. p. 21.

  • Bianchi, C. ; GUTKOWSKA, J. ; ANAND-SRIVASTAVA, M. B. ; DELEAN, A. ; GENEST, J. ; CANTIN, M. . Localization and characterization of atrial natriuretic factor (ANF) receptors in the ciliary processes of the eyes. In: The Endocrine Society Meeting, 1985. The Endocrine Society Meeting, 1985. v. 902. p. 226.

  • CANTIN, M. ; Bianchi, C. ; GUTKOWSKA, J. ; THIBAULT, G. ; GARCIA, R. ; GENEST, J. . Comparative localization and effect of ANF and angiotensin II on the glomerulus. An ultrastructural radioautographic and functional study. In: American Hypertension Society, 1985, Detroit. Hypertension, 1985. v. 8. p. 1327.

  • BIANCHI, C ; GUTKOWSKA, J. ; GENEST, J. ; CANTIN, M. . . Localization radioautographique in vivo de liaison du facteur natriuretic des oreillettes-125I (FNO-125I) chez le rat. In: Journee scientifique du Department de pathologie de l'Universite de Montreal, 1985, Montreal. Journee scientifique du Department de pathologie de l'Universite de Montreal, 1985. p. 12.

  • Bianchi, C. ; GUTKOWSKA, J. ; DELEAN, A. ; GENEST, J. ; CANTIN, M. . Internalization and fate of [125I]-labelled angiotensin II into the zona glomerulosa.. In: FEDERATION AMER SOC EXP BIOL, 1984. FEDERATION PROCEEDINGS, 1984. v. 43. p. 3035.

  • Bianchi, C. ; GUTKOWSKA, J. ; DELEAN, A. ; GENEST, J. ; CANTIN, M. . Internalization pathway of 125I-AII in the zona glomerulosa of the adrenal cortex. In: International Congress of Endocrinology, 1984. Proceedings of the 7th International Congress of Endocrinology, 1984. v. 18. p. 269.

  • BIANCHI, C ; CANTIN, M. . L'internalization et la degradation de l'angiotensine II-I125 dans la surrenale du rat.. In: III Congress Annuel de l'association des etudiants aux grades superieurs de la faculte de Medicine de l'Universite de Montreal, 1984, Montreal. Congress Annuel de l'association des etudiants aux grades superieurs de la faculte de Medicine de l'Universite de Montreal, 1984. p. 17.

  • Bianchi, C. ; GUTKOWSKA, J. ; CANTIN, M. ; GENEST, J. . Binding and Internalization of angiotensin II in rat adrenal. In: FEDERATION AMER SOC EXP BIOL, 1983, Bathesda. FEDERATION PROCEEDINGS. Bathesda: FEDERATION PROCEEDINGS, 1983. v. 42. p. 1102.

  • Bianchi, C. ; GUTKOWSKA, J. ; ANAND-SRIVASTAVA, M. B. ; CANTIN, M. ; GENEST, J. . Binding and internalization of angiotensin II in the rat adrenal. In: Canadian Federation of Biological Societies, 1983, Toronto. Canadian Federation of Biological Societies, 1983. v. 26. p. 87.

  • Bianchi, C. ; GUTKOWSKA, J. ; GENEST, J. ; CANTIN, M. . Binding and internalization of 125I-AII in the zona glomerulosa of the adrenal cortex.. In: Physiology Canada, 1983, Ottawa. Physiology Canada, 1983. v. 14. p. 82.

  • BIANCHI, C ; CANTIN, M. . Liaison et internalization de l'angiotensin II-I125 dans la surrenale de rat. Etude radioautographique ultrastructurale. In: Journee de la recherche du Departement de Medicine, Universite de Montreal, 1983, Montreal. Journee de la recherche du Departement de Medicine, 1983. p. 1.

  • CANTIN, M. ; GUTKOWSKA, J. ; ANAND-SRIVASTAVA, M. B. ; LEDOUX, S. ; Bianchi, C. ; CARRIERE, P. ; GENEST, J. . Binding and internalization of 125I-angiotensin II in the rat adrenal. An ultrastructural radioautographic study. In: Cell Biology Meeting, 1982, New York. J Cell BIol. New York: ROCKEFELLER UNIV PRESS, 1982. v. 95. p. 411a.

  • YABUUTI, P. L. K. ; BURATTI, A. ; JESUS, G. M. ; BASSANI, G. A. ; CASTRO, H. ; SILVA, J. P. ; NAKAMOTO, J. M. ; GUSHIKEN, E. S. ; Bianchi, Cesario ; GONCALVES, I. O. . O Exercício Fisico na Terceira Idade como Instrumento de Promoção da Saúde. REVISTA ELETRÔNICA ACERVO EM SAÚDE , 2018.

  • Bianchi, C. . Trabalhos Científicos: Importância e repercussão na vida profissional. 2017. (Apresentação de Trabalho/Seminário).

  • Bianchi, Cesario F. . Angiologia e Cirurgia Vascular, Diagnóstico or imagem, Endocrinologia e Metabologia e Geriatria. 2016. (Apresentação de Trabalho/Simpósio).

  • BIANCHI, C . Elaboração de um Projeto de Pesquisa Cientifica na Área da Saúde. 2016. (Apresentação de Trabalho/Seminário).

  • BIANCHI, C . O Papel da Iniciação Científica na Construção da Carreira Profissional. 2016. (Apresentação de Trabalho/Seminário).

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Outras produções

Bianchi, C. . Introdução a Fisiologia Humana. 2018. (Curso de curta duração ministrado/Especialização).

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Projetos de pesquisa

  • 2017 - Atual

    Alterações Cardiovasculares na Caquexia de Origem Neoplásica, Descrição: Caquexia é uma síndrome, multifatorial associada a doenças crônicas como a sepse, AIDS (síndrome da imunodeficiência adquirida), insuficiência cardíaca crônica, e câncer. Cerca de 60-80% dos pacientes com câncer são acometidos por caquexia. A caquexia é responsável por ~20% das mortes desses pacientes. Pesquisadores nessa área buscam uma melhor caracterização para essa síndrome que é de difícil tratamento. A caquexia é definida pela perda de massa corpórea superior a 5%, Índice de Massa Corpórea (IMC) menor que 20 e sarcopenia. Em pacientes oncológicos com caquexia há um aumento na progressão do câncer, já que estes não respondem/resistem bem as terapias. A caquexia associada ao câncer afeta muitos órgãos, como cérebro, intestino, fígado e coração. Há perda de massa corpórea e inflamação principalmente dos tecidos musculares (incluindo alterações cardíacas) e adiposo, que podem levar a óbito. Os problemas cardíacos são comuns em pacientes com câncer e durante a progressão do estado caquético o miocárdio sofre alterações, como aumento de fatores pró-inflamatórios, a diminuição do tamanho dos cardiomiócitos, aumento da autofagia, diminuição da inervação, atrofia, aumento do consumo de energia, diminuição das miofibrilas e arritmias. O coração é um dos órgãos mais afetados durante a caquexia, sendo que a insuficiência cardíaca e arritmias são duas das causas importantes de óbitos nesses pacientes; no entanto pouco estudadas, alterações nas fibras cardíacas pode causar disfunções cardiacas. Em termos de tratamentos para a caquexia induzida pelo câncer, o uso farmacológico tem sido o mais frequente ao longo dos anos. Recentemente foi incorporado o exercício físico, um tratamento não farmacológico, que visa a melhoria da qualidade de vida desses pacientes. Estudos apontam que o exercício resistido provem bons resultados ao sistema cardíaco vascular, particularmente em pacientes com caquexia associada ao câncer, mas os efeitos nessa condição ainda não foram estudados em maior detalhe. Objetivo geral Analisar os efeitos da caquexia associada ao câncer em células cardíacas (fibroblastos, cardiomiócitos e coronárias) e determinar se a caquexia induzido por neoplasias em camundongos está associado à atrofia do coração e outras alterações cardiovasculares.. , Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (1) . , Integrantes: Cesario Bianchi Filho - Coordenador.

  • 2016 - 2017

    Núcleo de Pesquisa Clínica e Translacional, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Coordenador.

  • 2014 - Atual

    Efeito do Extrato Etanólico da Casca de Pequi (Caryocar brasiliense) na Isquemia Aguda do Miocárdio em Suínos Hipercolesterolêmicos, Projeto certificado pelo(a) coordenador(a) Eugenio Gonçalves de Araujo em 31/10/2014., Descrição: A redução do suplemento de oxigenação ao coração resulta na doença cardíaca isquêmica, que pode ser causada por uma redução aguda ou crônica do fluxo sanguíneo coronariano em relação à demanda do miocárdio. As principais causas da redução do fluxo são processos intravasculares (aterosclerose, trombose), que reduzem ou obstruem o lúmen coronariano. Entre os fatores que causam ou contribuem para tais processos, a hipercolesterolemia é considerada um dos três mais importantes, juntamente com a hipertensão e a diabete. Tais processos patológicos, que cursam com isquemia e reperfusão, têm como consequência a produção de radicais livres, os quais estão envolvidos na oxidação de macromoléculas celulares e podem contribuir para a patofisiologia da injúria celular. O pequi (Caryocar brasiliense) é um fruto do cerrado cujo extrato etanólico da casca apresenta fenóis que demonstraram elevada capacidade de neutralizar radicais livres in vitro. Aventou-se a hipótese de que o extrato etanólico da casca de pequi pode reduzir lesões de isquemia e reperfusão experimental em suínos submetidos à dieta hiperlipídica. Suínos hipercolesterolêmicos serão distribuídos aleatoriamente em três grupos de tratamento. Os grupos serão: 1) placebo (n=7), 2) tratamento com resveratrol na dose de 100mg/kg PV (n=7) e 3) tratamento com extrato etanólico da casca de pequi, utilizado na mesma concentração do resveratrol (100mg/kg PV). Para efeito de comparação, serão utilizados 3 grupos conforme descritos anteriormente, mas os animais receberão apenas ração de crescimento (normocolesterolêmica). Após 1 semana da introdução da dieta experimental, a droga e o placebo serão fornecidos diariamente, no período da manhã, durante três semanas, os animais serão submetidos à isquemia regional no ventrículo esquerdo por 60 minutos, seguida por 120 minutos de reperfusão Ao final, o coração será extirpado e amostras de tecido da área afetada serão coletadas para análise molecular. Serão obtidos dados de quantificação das áreas de infarto e de risco do miocárdio, hemograma e perfil lipídico, western blotting e imunoistoquímica para diferentes vias de transdução de sinal potencialmente afetadas pela isquemia e reperfusão, além da quantificação de apoptose. A utilização de um extrato obtido de uma parte não comestível de uma planta do cerrado brasileiro para a prevenção e tratamento de doenças isquêmicas pode constituir uma alternativa de aproveitamento sustentável da vegetação nativa daquele importante bioma.. , Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (1) / Mestrado acadêmico: (2) / Doutorado: (3) . , Integrantes: Cesario Bianchi Filho - Integrante / Eugenio Gonçalves de Araujo - Coordenador / Maria Clorinda Soares Fioravanti - Integrante / Luciana Batalha de Miranda Araujo - Integrante.

  • 2014 - Atual

    Ação do Extrato Etanólico da Casca de Pequi (Caryocar brasiliense) no Estresse Oxidativo em Miocárdio e Células Endoteliais do Coração de Camundongos (Mus musculus) Transgênicos, Projeto certificado pelo(a) coordenador(a) Eugenio Gonçalves de Araujo em 31/10/2014., Descrição: O cerrado é a vegetação predominante da região Centro-Oeste do Brasil, onde frutos como o pequi (Caryocar brasiliense) são amplamente conhecidos porém pouco explorados quanto a suas propriedades farmacológicas. O pequi possui alta concentração de fenóis com capacidade de neutralizar radicais livres de oxigênio. Dessa forma, este trabalho tem o objetivo de verificar o efeito, e investigar os mecanismos celulares e moleculares de proteção, da terapia antioxidante com extrato etanólico da casca de pequi em cultura de células endoteliais de coração de camundongos Tet-Nox2:VE-Cad-tTA por indução experimental de isquemia e reperfusão e também no miocárdio após ligação do ramo anterior descendente da artéria coronária esquerda. Placas de cultura serão agrupadas aleatoriamente em dez grupos de dez placas cada e submetidas ou não aos tratamentos com o extrato de pequi em diferentes concentrações do antioxidante previamente preparado. Serão realizados western blot e imunofluorescência, procurando estabelecer o perfil de expressão de marcadores de sobrevivência, autofagia e apoptosealém da dosagem de estresse oxidativo. Em um segundo experimento, camundongos transgênicos Tet-Nox2:VE-Cad-tTA receberão ou não extrato etanólico da casca de pequi, após período experimental de superexpressão ou não de NADPH oxidase mediada por tetraciclina. Esta investigação procurará verificar o efeito do tratamento antioxidante, na qual se espera a minimização da disfunção e de morte celular. Espera-se obter importantes respostas sobre o mecanismo da eventual ação antioxidante dos componentes do extrato etanólico da casca de pequi sobre células endoteliais e musculares cardíacas, podendo descortinar o potencial terapêutico de um fruto que é símbolo do cerrado brasileiro.. , Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (1) / Mestrado acadêmico: (2) / Doutorado: (3) . , Integrantes: Cesario Bianchi Filho - Integrante / Eugenio Gonçalves de Araujo - Coordenador / Luciana Batalha de Miranda Araujo - Integrante / Ruhul Abid - Integrante / Yandra Cassia Lobato de Prado - Integrante / Luciana Batalha Miranda Araujo - Integrante / Marina Pacheco Miguel - Integrante.

  • 2010 - 2014

    mTOR and Myocardial Ischemic Injury, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Coordenador., Financiador(es): American Heart Association - Grant-In-Aid - Auxílio financeiro.

  • 2008 - 2014

    Cardioplegia and coronary microvascular reactivity, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Frank William Sellke - Coordenador., Financiador(es): National Institutes of Health - Auxílio financeiro.

  • 2008 - 2012

    Surgical Intramyocardial Angiogenesis in a Swine Model, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Frank William Sellke - Coordenador., Financiador(es): National Institutes of Health - Auxílio financeiro.

  • 2008 - 2010

    Angiogenesis in a model of diabetes and endothelial dysfunction, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Frank William Sellke - Coordenador., Financiador(es): National Institutes of Health - Auxílio financeiro.

  • 2004 - 2009

    Cardiovascular Surgery Research Training Grant, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Frank William Sellke - Coordenador., Financiador(es): National Institutes of Health - Auxílio financeiro.

  • 2002 - 2007

    Surgical Intramyocardial Angiogenesis in a Swine Model, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Frank William Sellke - Coordenador., Financiador(es): National Institutes of Health - Auxílio financeiro.

  • 2002 - 2005

    Cardioplegia and coronary microvascular reactivity, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Frank William Sellke - Coordenador., Financiador(es): National Institutes of Health - Auxílio financeiro.

  • 1997 - 2002

    Cardioplegia and coronary microvascular reactivity, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Frank William Sellke - Coordenador., Financiador(es): Specialized Center of Research in Molecular Medicine & Atherosclerosis, NIH - Auxílio financeiro.

  • 1997 - 2000

    Role of RPTPmu and SHPTP2 in Vascular Endothelial Cells, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Lewis C. Cantley - Coordenador., Financiador(es): Specialized Center of Research in Molecular Medicine & Atherosclerosis, NIH - Auxílio financeiro.

  • 1992 - 1994

    Signal transduction in vascular cells, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Cesario Bianchi Filho - Integrante / Haber, Edgar - Coordenador., Financiador(es): Bristol-Myers Squibb Pharmaceutical Research Institute - Auxílio financeiro.

Seção coletada automaticamente pelo Escavador

Prêmios

2016

American Heart Association Fellow (FAHA), American Heart Association Council on Cardiovascular Surgery and Anesthesia (CVSA).

2012

Master of Arts (Ad Eundem), Brown University.

1989

Postdoctoral Fellowship Award, Medical Research Council of Canada.

1988

Postdoctoral Fellowship Award, Fonds de la Recherche en Sante du Quebec, Canada (declined).

1986

Fellowship Award, Medical Research Council of Canada.

1985

Fellowship Award, Canadian Heart Foundation.

1982

Roger Boucher Award, Clinical Research Institute of Montreal.

Histórico profissional

Seção coletada automaticamente pelo Escavador

Endereço profissional

  • Universidade de Mogi das Cruzes, Centro de Ciências Biomédicas. , Avenida Cândido Xavier de Almeida e Souza, Centro Cívico, 08780210 - Mogi das Cruzes, SP - Brasil, Telefone: (11) 47987083

Seção coletada automaticamente pelo Escavador

Experiência profissional

  • 2015 - Atual

    Universidade de Mogi das Cruzes

    Vínculo: Celetista, Enquadramento Funcional: Professor e pesquisador, Carga horária: 40

    Outras informações:
    Ministrou na disciplina de Fisiologia Humana no curso de Medicina (2016-2017) Ministra na disciplina de Iniciação Científica no curso de Medicina (2016- atual) Ministra na disciplina de Pesquisa Clínica no curso de Farmácia (2017- atual)

  • 2016 - 2017

    Universidade Brasil

    Vínculo: Professor e pesquisador, Enquadramento Funcional: Professor titular, Carga horária: 20

  • 2014 - 2015

    Centro Nacional de Pesquisa em Energia e Materiais

    Vínculo: Professor Visitante, Enquadramento Funcional: Professor vsitiante, Carga horária: 40, Regime: Dedicação exclusiva.

  • 2014 - 2014

    Universidade Federal de Goiás

    Vínculo: Professor Visitante, Enquadramento Funcional: part-time

  • 2009 - 2014

    Brown University, Rhode Island Hospital

    Vínculo: Pesquisador, Enquadramento Funcional: Pesquisador

  • 2009 - 2014

    Brown University, Rhode Island Hospital

    Vínculo: Professor Associado, Enquadramento Funcional: Professor Associado, Carga horária: 40, Regime: Dedicação exclusiva.

    Atividades

    • 11/2009 - 03/2014

      Direção e administração, Dept. of Surgery, Division of Cardiothoracic Surgery Research Laboratory, .,Cargo ou função, Director of the Cardiothoracic Surgery Research Laboratory.

    • 11/2009 - 03/2014

      Pesquisa e desenvolvimento , Dept. of Surgery, Division of Cardiothoracic Surgery Research Laboratory, .,Linhas de pesquisa

  • 2013 - 2014

    Harvard University

    Vínculo: Professor Visitante, Enquadramento Funcional: part-time

  • 2001 - 2009

    Harvard Medical School

    Vínculo: Assistant Professor, Enquadramento Funcional: Assistant Professor, Carga horária: 40, Regime: Dedicação exclusiva.

  • 1992 - 2001

    Harvard Medical School

    Vínculo: Instructor in Medicine/Surgery, Enquadramento Funcional: Instructor in Medicine/Surgery, Carga horária: 40, Regime: Dedicação exclusiva.

    Atividades

    • 01/1992 - 10/2009

      Pesquisa e desenvolvimento , Beth Israel Deaconess Medical Center, .,Linhas de pesquisa

  • 1992 - 1994

    Harvard School Of Public Health

    Vínculo: Pesquisador, Enquadramento Funcional: Pesquisador