ChengShi Jiang

Possui graduação em Chemistry pela Qufu Normal University(2007) e doutorado em Medicinal Chemestry pela Chinese Academy of Sciences(2012). Tem experiência na área de Química, com ênfase em Medicinal Chemistry.

Informações coletadas do Lattes em 29/11/2024

Acadêmico

Formação acadêmica

Doutorado em Medicinal Chemestry

2007 - 2012

Chinese Academy of Sciences
Título: Synthesis and Biological Evaluation of two Marine Natural Products and a Series of 21-Arylidenepregnenolone Derivatives, and Investigation toward Synthesis of Bruguiesulfurol
Orientador: Yue Wei Guo

Graduação em Chemistry

2003 - 2007

Qufu Normal University
Título: Study on aldol condensation reaction of cyclohexanone catalyzed by solid superbase
Orientador: Gen-Zhi Gao

Idiomas

Bandeira representando o idioma Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Bandeira representando o idioma Chinês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Áreas de atuação

Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Medicinal Chemistry.

Produções bibliográficas

  • CHEN, JING ; GAO, LI-XIN ; GONG, JING-XU ; JIANG, CHENG-SHI ; YAO, LI-GONG ; LI, JING-YA ; LI, JIA ; XIAO, WEI ; GUO, YUE-WEI . Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors. Bioorganic & Medicinal Chemistry Letters (Print) , v. 25, p. 2211-2216, 2015.

  • XU, JING ; JIANG, CHENG-SHI ; ZHANG, ZAI-LONG ; MA, WEN-QUAN ; GUO, YUE-WEI . Recent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides. Acta Pharmacologica Sinica , v. 35, p. 316-330, 2014.

  • JIANG, CHENG-SHI ; LI, YAN ; HAN, GUAN-YING ; GUO, YUE-WEI . Further casbane-type diterpenes from the soft coral Sinularia depressa. Chinese Journal of Natural Medicines (Online) , v. 12, p. 853-856, 2014.

  • WANG, LI-LI ; JIANG, CHENG-SHI ; FU, YAN ; CHEN, FEI-FEI ; LAN, LE-FU ; ZHANG, HAI-YAN ; GUO, YUE-WEI . Two New Limonoids from the Root Bark of Chinese Medicinal Plant. Helvetica Chimica Acta , v. 97, p. 1301-1306, 2014.

  • LI, JING ; WANG, JUN ; JIANG, CHENG-SHI ; LI, GANG ; GUO, YUE-WEI . (+)-Cyclopenol, a new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid from the fungus endogenous with the Chinese mangrove. Journal of Asian Natural Products Research , v. 16, p. 542-548, 2014.

  • SUN, JI-ZHENG ; JIANG, CHENG-SHI ; CHEN, XUE-QIN ; CHEN, KAO-SHAN ; ZHEN, XUE-CHU ; VAN SOEST, ROB W.M. ; GUO, YUE-WEI . Topsendines A-F, new 3-alkylpyridine alkaloids from a Hainan sponge Topsentia sp.. Tetrahedron (Oxford. Print) , v. 70, p. 3166-3171, 2014.

  • JIANG, CHENG-SHI ; FU, YAN ; ZHANG, LI ; GONG, JING-XU ; WANG, ZHEN-ZHONG ; XIAO, WEI ; ZHANG, HAI-YAN ; GUO, YUE-WEI . Synthesis and biological evaluation of novel marine-derived indole-based 1,2,4-oxadiazoles derivatives as multifunctional neuroprotective agents. Bioorganic & Medicinal Chemistry Letters (Print) , v. 25, p. 216-220, 2014.

  • ZHOU, RONG ; LIN, ZHONG-HUI ; JIANG, CHENG-SHI ; GONG, JING-XU ; CHEN, LI-LI ; GUO, YUE-WEI ; SHEN, XU . Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation. Acta Pharmacologica Sinica , v. 34, p. 1325-1336, 2013.

  • CHEN, JING ; JIANG, CHENG-SHI ; MA, WEN-QUAN ; GAO, LI-XIN ; GONG, JING-XU ; LI, JING-YA ; LI, JIA ; GUO, YUE-WEI . The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors. Bioorganic & Medicinal Chemistry Letters (Print) , v. 23, p. 5061-5065, 2013.

  • JIANG, CHENG-SHI ; LI, YAN ; WANG, ZHEN-ZHONG ; HUANG, XIAO-YIN ; XIAO, WEI ; GUO, YUE-WEI . Cipatrijugin G, a new trijugin-type limonoid bearing an uncommon γ-hydroxybutenolide unit from the aerial parts of Cipadessa cinerascens. Natural Products and Bioprospecting , v. 3, p. 267-270, 2013.

  • JIANG, CHENG-SHI ; GUO, XIAN-JUN ; GONG, JING-XU ; ZHU, TING-TING ; ZHANG, HAI-YAN ; GUO, YUE-WEI . Synthesis and biological evaluation of 21-arylidenepregnenolone derivatives as neuroprotective agents. Bioorganic & Medicinal Chemistry Letters (Print) , v. 22, p. 2226-2229, 2012.

  • JIANG, CHENG-SHI ; MÜLLER, WERNER E. G. ; SCHRÖDER, HEINZ C. ; GUO, YUE-WEI . Disulfide- and Multisulfide-Containing Metabolites from Marine Organisms. Chemical Reviews , v. 112, p. 2179-2207, 2012.

  • JIANG, CHENG-SHI ; LIANG, LIN-FU ; GUO, YUE-WEI . Natural products possessing protein tyrosine phosphatase 1B (PTP1B) inhibitory activity found in the last decades. Acta Pharmacologica Sinica , v. 33, p. 1217-1245, 2012.

  • JIANG, C.-S. ; GUO, Y.-W. . Epipolythiodioxopiperazines from Fungi: Chemistry and Bioactivities. Mini-Reviews in Medical Chemistry , v. 11, p. 728-745, 2011.

  • JIANG, CHENG-SHI ; ZHOU, RONG ; GONG, JING-XU ; CHEN, LI-LI ; KURTÁN, TIBOR ; SHEN, XU ; GUO, YUE-WEI . Synthesis, modification, and evaluation of (R)-de-O-methyllasiodiplodin and analogs as nonsteroidal antagonists of mineralocorticoid receptor. Bioorganic & Medicinal Chemistry Letters (Print) , v. 21, p. 1171-1175, 2011.

  • JIANG, CHENG-SHI ; FENG, BO ; LI, JIA ; GONG, JING-XU ; KURTÁN, TIBOR ; GUO, YUE-WEI . Synthesis and antitumor evaluation of methyl spongoate analogs. Steroids (Stoneham, MA.) , v. 75, p. 1153-1163, 2010.

  • GONG, JING-XU ; HE, WEN-FEI ; LIU, HAI-LI ; JIANG, CHENG-SHI ; WANG, TING ; WANG, HE-YAO ; GUO, YUE-WEI . Synthesis and Evaluation of Pancreatic Lipase Inhibitory Effects Halogenated Polyunsaturated Lipids from Marine Natural Products: Methyl Xestospongoate and Analogs. Helvetica Chimica Acta , 2016.

  • ZHANG, LI ; JIANG, CHENG-SHI ; GAO, LI-XIN ; GONG, JING-XU ; WANG, ZHONG-HUA ; LI, JING-YA ; LI, JIA ; LI, XU-WEN ; GUO, YUE-WEI . Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity. Bioorganic & Medicinal Chemistry Letters (Print) , 2016.

Prêmios

2013

Best Paper Award, Shanghai Pharmaceutical Association.

2012

Excellent President Award of CAS, Chinese Academy of Sciences.

2011

Excellent Student Award of CSA, Chinese Academy of Sciences.

Histórico profissional

Experiência profissional

2012 - 2014

Shanghai Institute of Materia Medica, CAS, SIMM

Vínculo: Formal labor contract, Enquadramento Funcional: Assitant Professor, Regime: Dedicação exclusiva.