Nicolas Bertrand

Possui doutorado em Pharmaceutical Sciences - Université de Montreal (2011). Tem experiência na área de Nanopharmacology and pharmaceutical nanosciences.

Informações coletadas do Lattes em 29/11/2024

Acadêmico

Formação acadêmica

Doutorado em Pharmaceutical Sciences

2006 - 2011

Université de Montreal, UdeM
Título: Pharmacokinetics and pharmacodynamics evaluation of pH sensitive and liposomal formulations for drug delivery applications
Orientador: Jean-Christophe Leroux

Mestrado em Pharmaceutical Sciences

2003 - 2006

Université de Montreal, UdeM
Título: Evaluation de la libération des drogues à partir de microsphères polymères par automate cellulaire,Ano de Obtenção: 2006
Orientador: Prof Patrice Hildgen

Pós-doutorado

2011 - 2015

Pós-Doutorado. , Massachusetts Institute of Technology, MIT, Estados Unidos. , Bolsista do(a): Canadian Institute of Health Research, CIHR, Canadá. , Grande área: Engenharias, Grande Área: Ciências da Saúde / Área: Farmácia / Subárea: Nanomedicine.

Idiomas

Bandeira representando o idioma Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Bandeira representando o idioma Francês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Produções bibliográficas

  • PERREAULT, MARTIN ; MALTAIS, RENÉ ; ROY, JENNY ; PICARD, SYLVAIN ; POPA, ION ; Bertrand, Nicolas ; POIRIER, DONALD . Induction of endoplasmic reticulum stress by aminosteroid derivative RM-581 leads to tumor regression in PANC-1 xenograft model. INVESTIGATIONAL NEW DRUGS , v. 37, p. 431-440, 2019.

  • GRENIER, PHILIPPE ; VIANA, IARA MAÍRA DE OLIVEIRA ; LIMA, ELIANA MARTINS ; Bertrand, Nicolas . Anti-polyethylene glycol antibodies alter the protein corona deposited on nanoparticles and the physiological pathways regulating their fate in vivo. JOURNAL OF CONTROLLED RELEASE , v. 287, p. 121-131, 2018.

  • OUELLETTE, MATHIEU ; MASSE, FLORENCE ; LEFEBVRE-DEMERS, MATHILDE ; MAESTRACCI, QUENTIN ; GRENIER, PHILIPPE ; MILLAR, ROBERT ; Bertrand, Nicolas ; PRIETO, MANUEL ; BOISSELIER, ÉLODIE . Insights into gold nanoparticles as a mucoadhesive system. Scientific Reports , v. 8, p. 14357, 2018.

  • BISSO, PAUL W. ; TAI, MICHELLE ; KATEPALLI, HARI ; Bertrand, Nicolas ; BLANKSCHTEIN, DANIEL ; LANGER, ROBERT . Molecular Rotors for Universal Quantitation of Nanoscale Hydrophobic Interfaces in Microplate Format. NANO LETTERS , v. 18, p. 618-628, 2018.

  • MALTAIS, RENÉ ; TROTTIER, ALEXANDRE ; ROY, JENNY ; AYAN, DIANA ; Bertrand, Nicolas ; POIRIER, DONALD . Pharmacokinetic profile of PBRM in rodents, a first selective covalent inhibitor of 17β-HSD1 for breast cancer and endometriosis treatments. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY , v. 178, p. 167-176, 2018.

  • CHOPRA, SUNANDINI ; Bertrand, Nicolas ; LIM, JONG-MIN ; WANG, AMY ; FAROKHZAD, OMID C. ; KARNIK, ROHIT . Design of Insulin-Loaded Nanoparticles Enabled by Multistep Control of Nanoprecipitation and Zinc Chelation. ACS Applied Materials & Interfaces , v. 9, p. 11440-11450, 2017.

  • Bertrand, Nicolas ; GRENIER, PHILIPPE ; MAHMOUDI, MORTEZA ; LIMA, ELIANA M. ; APPEL, ERIC A. ; DORMONT, FLAVIO ; LIM, JONG-MIN ; KARNIK, ROHIT ; LANGER, ROBERT ; FAROKHZAD, OMID C. . Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics. Nature Communications , v. 8, p. 777, 2017.

  • MAHMOUDI, MORTEZA ; Bertrand, Nicolas ; ZOPE, HARSHAL ; FAROKHZAD, OMID C. . Emerging understanding of the protein corona at the nano-bio interfaces. Nano Today , v. 11, p. 817-832, 2016.

  • XU, XIAOYANG ; HO, WILLIAM ; ZHANG, XUEQING ; Bertrand, Nicolas ; FAROKHZAD, OMID . Cancer nanomedicine: from targeted delivery to combination therapy. TRENDS IN MOLECULAR MEDICINE , v. 21, p. 223-232, 2015.

  • WU, JUN ; ZHAO, LILI ; XU, XIAODING ; Bertrand, Nicolas ; CHOI, WON II ; YAMEEN, BASIT ; SHI, JINJUN ; SHAH, VISHVA ; MULVALE, MATTHEW ; MACLEAN, JAMES L. ; FAROKHZAD, OMID C. . Hydrophobic Cysteine Poly(disulfide)-based Redox-Hypersensitive Nanoparticle Platform for Cancer Theranostics. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , v. 54, p. 9218-9223, 2015.

  • BRANDL, FERDINAND ; Bertrand, Nicolas ; LIMA, ELIANA MARTINS ; LANGER, ROBERT . Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil. Nature Communications , v. 6, p. 7765, 2015.

  • BERTRAND, NICOLAS ; WU, JUN ; XU, XIAOYANG ; KAMALY, NAZILA ; FAROKHZAD, OMID C. . Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology. Advanced Drug Delivery Reviews , v. 66, p. 2-25, 2014.

  • LIM, JONG-MIN ; BERTRAND, NICOLAS ; VALENCIA, PEDRO M. ; RHEE, MINSOUNG ; LANGER, ROBERT ; JON, SANGYONG ; FAROKHZAD, OMID C. ; KARNIK, ROHIT . Parallel microfluidic synthesis of size-tunable polymeric nanoparticles using 3D flow focusing towards in vivo study. Nanomedicine , v. 10, p. 401-409, 2014.

  • SWAMI, A. ; REAGAN, M. R. ; BASTO, P. ; MISHIMA, Y. ; KAMALY, N. ; GLAVEY, S. ; ZHANG, S. ; MOSCHETTA, M. ; SEEVARATNAM, D. ; ZHANG, Y. ; LIU, J. ; MEMARZADEH, M. ; WU, J. ; MANIER, S. ; SHI, J. ; BERTRAND, N. ; LU, Z. N. ; NAGANO, K. ; BARON, R. ; SACCO, A. ; ROCCARO, A. M. ; FAROKHZAD, O. C. ; GHOBRIAL, I. M. . Engineered nanomedicine for myeloma and bone microenvironment targeting. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , v. 111, p. 10287-10292, 2014.

  • ZHANG, XUE-QING ; XU, XIAOYANG ; BERTRAND, NICOLAS ; PRIDGEN, ERIC ; SWAMI, ARCHANA ; FAROKHZAD, OMID C. . Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine. Advanced Drug Delivery Reviews , v. 64, p. 1363-1384, 2012.

  • BEAUREGARD, N. ; BERTRAND, N. ; DUFOUR, A. ; BLAIZEL, O. ; LECLAIR, G. . Physical compatibility of calcium gluconate and magnesium sulfate injections. American Journal of Health-System Pharmacy , v. 69, p. 98-98, 2012.

  • BERTRAND, NICOLAS ; LEROUX, JEAN-CHRISTOPHE . The journey of a drug-carrier in the body: An anatomo-physiological perspective. Journal of Controlled Release , v. 161, p. 152-163, 2012.

  • BERTRAND, NICOLAS ; GAUTHIER, MARC A. ; BOUVET, CÉLINE ; MOREAU, PIERRE ; PETITJEAN, ANNE ; LEROUX, JEAN-CHRISTOPHE ; LEBLOND, JEANNE . New pharmaceutical applications for macromolecular binders. Journal of Controlled Release , v. 155, p. 200-210, 2011.

  • BERTRAND, NICOLAS ; BOUVET, CE'LINE ; MOREAU, PIERRE ; LEROUX, JEAN-CHRISTOPHE . Transmembrane pH-Gradient Liposomes To Treat Cardiovascular Drug Intoxication. ACS Nano , v. 4, p. 7552-7558, 2010.

  • BERTRAND, NICOLAS ; FLEISCHER, JACKIE G. ; WASAN, KISHOR M. ; LEROUX, JEAN-CHRISTOPHE . Pharmacokinetics and biodistribution of N-isopropylacrylamide copolymers for the design of pH-sensitive liposomes. Biomaterials (Guildford) , v. 30, p. 2598-2605, 2009.

  • BERTRAND, N ; HILDGEN, P . Modeling drug release from bioerodible microspheres using a cellular automaton. International Journal of Pharmaceutics (Print) , v. 343, p. 196-207, 2007.

  • ELSABAHY, MAHMOUD ; PERRON, MARIE-ÈVE ; BERTRAND, NICOLAS ; YU, GA-ER ; LEROUX, JEAN-CHRISTOPHE . Solubilization of Docetaxel in Poly(ethylene oxide)- -poly(butylene/styrene oxide) Micelles. Biomacromolecules , v. 8, p. 2250-2257, 2007.

  • Bertrand, Nicolas ; Simard, Pierre ; LEROUX, JEAN-CHRISTOPHE . Methods in Molecular Biology. 1. ed. Humana Press, 2010.

Prêmios

2019

GlaxoSmithKline/CSPS Early Career Award, Canadian Society for Pharmaceutical Sciences.

2019

Etoile Effervescence 2019, Montreal In Vivo.

Histórico profissional

Endereço profissional

  • Université Laval. , 1050 Ave de la Médecine, 1050, G1V0A6 - Quebec, - Canadá, Telefone: (418) 5254444

Experiência profissional

2016 - Atual

Elsevier B.V.

Vínculo: Editor, Enquadramento Funcional: Editor of Eur J Pharm Biopharm