Jamal Ghazi Amiry

Idiomas

Áreas de atuação

Projetos de pesquisa

• 2015 - Atual

  Testing the expression of ERAP1 in human gut intestinal cells, Descrição: No studies were being done on human intestinal cell lines looking at the expression of ERAP1, which is associated to the ankylosing spondylitis. The aim was to inhibit ERAP1 in these cell lines because of an improvement in HLA-B27 folding that exhibited dramatic skeletal disease but without gut inflammation. The methods used were immunoblotting and flow cytometry to look at the presence of ERAP1 expression and the components of MHC class I. PCR was performed to look at the different ERAP1 isoforms within these cell lines and inhibiting ERAP1 by human cytomegalyvirus miRNA US-4 in Caco-2 cells that showed an 60% inhibition in other cell lines but not intestinal cells. The results were present of ERAP1 and MHC components in two cell lines tested (Caco-2 and T84), where HeLa cell lines used as control. ERAP1 isofroms showed to be present in Caco-2 in both forms but absence of one form in T84 cells which might help in inhibiting ERAP1 to 100%. As conclusion, It is possible that ERAP1 activity determines the role of HLA-B27 in autoimmune inflammatory arthritis, which could be a key for explaining the disease onset.. , Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (1) . , Integrantes: Jamal Ghazi Amiry - Coordenador / Antony N. Antoniou - Integrante.

• 2012 - 2012

  The antimicrobial activity of sweet cherry (Prunus avium) extracts: I. Measurement of sensitivity and attenuation of gram-positive and gram-negative bacteria and C. albicans in culture, Descrição: The antimicrobial activity of sweet cherry (Prunus avium) extracts: I.& II. Measurement of sensitivity and attenuation of gram-positive and gram-negative bacteria and C. albicans in culture. Curr. Nutr. Food Sci., 2012, 8, 275-291. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (4) / Especialização: (1) / Doutorado: (1) . , Integrantes: Jamal Ghazi Amiry - Coordenador / John Haddad - Integrante / Lama Hanabli - Integrante / Hiba Hassan - Integrante / Ali Tarraf - Integrante / Sarah koussan - Integrante.

• 2012 - 2012

  The Antimicrobial Activity of Sweet Cherry (Prunus avium) Extracts: II. Measurement of Sensitivity and Attenuation of Gram-Positive and Gram- Negative Bacteria and C. albicans in Culture, Descrição: The antimicrobial activity of sweet cherry (Prunus avium) extracts: II. Measurement of sensitivity and attenuation of gram-positive and gram-negative bacteria and C. albicans in culture. Curr. Nutr. Food Sci., 2012, 8, 292-303.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (4) / Especialização: (1) / Doutorado: (1) . , Integrantes: Jamal Ghazi Amiry - Coordenador / John Haddad - Integrante / Lama Hanabli - Integrante / Hiba Hassan - Integrante / Ali Tarraf - Integrante / Sarah koussan - Integrante.