Giovanna Gomes Lara

Áreas de atuação

Organização de eventos

Participação em eventos

Produções bibliográficas

• LARA, Giovanna Gomes ; ANDRADE, GRACIELLE FERREIRA ; CIPRESTE, MARCELO FERNANDES ; DA SILVA, WELLINGTON MARCOS ; GASTELOIS, PEDRO LANA ; GOMES, DAWIDSON ASSIS ; DE MIRANDA, MARCELO COUTINHO ; DE ALMEIDA MACEDO, WALDEMAR AUGUSTO ; NEVES, MARIA JOSE ; DE SOUSA, EDÉSIA MARTINS BARROS . Protection of normal cells from irradiation bystander effects by silica-flufenamic acid nanoparticles. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE , v. 29, p. 130, 2018.

• Giovanna Gomes Lara ; Marcelo Fernandes Cipreste ; Gracielle Ferreira Andrade ; Wellington Marcos da Silva ; Edésia Martins Barros de Sousa . Response of Fibroblasts MRC-5 to Flufenamic Acid-Grafted MCM-41 Nanoparticles. Bioengineering , v. 5, p. 4, 2018.

• LARA, GIOVANNA G. ; HAZENBILLER, OLESJA ; GAREAU, TIA ; SHEPHERD, ROBERT D. ; KALLOS, MICHAEL S. ; RANCOURT, DERRICK E. ; RINKER, KRISTINA D. . Fluid Flow Modulation of Murine Embryonic Stem Cell Pluripotency Gene Expression in the Absence of LIF. CELL MOL BIOENG , v. 6, p. 335-345, 2013.

• GAREAU, TIA ; LARA, GIOVANNA G. ; SHEPHERD, ROBERT D. ; KRAWETZ, ROMAN ; RANCOURT, DERRICK E. ; RINKER, KRISTINA D. ; KALLOS, MICHAEL S. . Shear stress influences the pluripotency of murine embryonic stem cells in stirred suspension bioreactors. Journal of Tissue Engineering and Regenerative Medicine , v. 8, p. n/a-n/a, 2012.

• POMPERMAYER, KENIA ; SOUZA, DANIELLE G. ; LARA, GIOVANNA G. ; SILVEIRA, KATIA D. ; CASSALI, GEOVANNI D. ; ANDRADE, ANDERSON A. ; BONJARDIM, CLAUDIO A. ; PASSAGLIO, KATIA T. ; ASSREUY, JAMIL ; CUNHA, FERNANDO Q. ; VIEIRA, MARIA APARECIDA R. ; TEIXEIRA, MAURO M. . The ATP-sensitive potassium channel blocker glibenclamide prevents renal ischemia/reperfusion injury in rats. Kidney International , v. 67, p. 1785-1796, 2005.

Outras produções

Projetos de pesquisa

• 2014 - Atual

  Nanopartículas mesoporosas de sílica, bloqueadores de junções-gap e efeitos bystander de radioterapia, Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Doutorado: (1) . , Integrantes: Giovanna Gomes Lara - Coordenador / Edésia Martins Barros de Sousa - Integrante., Financiador(es): Centro de Desenvolvimento e Tecnologia Nuclear - Bolsa.

• 2009 - 2011

  Fluid Flow Modulation of Murine Embryonic Stem Cell Pluripotency Gene Expression in the Absence of LIF, Descrição: Fluid forces are strong modulators of cell fate and fundamental components of spinner flask bioreactors used for stem cell expansion and differentiation. Here, we investigated the effects of fluid forces on murine embryonic stem cells (mESCs) in the absence of Leukemia Inhibitory Factor (LIF) using parallel-plate flow chambers. Cells were seeded onto gelatin-coated glass slides and grown for 2.5 days before exposure to fluid forces. Pluripotency marker gene expression was quantified by qPCR. An average shear stress of 0.6 Pa applied for 24 h in the absence of LIF and presence of high molecular weight dextran increased Oct4 and Sox2, decreased Nanog, and did not change in Rex1 mRNA levels in comparison to statically cultured cells in the presence of LIF. At 0.3 Pa shear stress, Oct4 and Sox2 expression increased, with a reduction in Nanog and Rex1 levels. The presence of pulsation significantly increased expression of Rex1 and Nanog, but not expression of Oct4 or Sox2, compared to cells exposed to steady flow for 24 h. This study suggests incorporation of high cell?cell contact, viscosity elevation with dextran, moderate shear stress (0.6 Pa), and the presence of pulsatility in bioreactor expansion protocols for mESCs to support maintenance of pluripotency.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (1) . , Integrantes: Giovanna Gomes Lara - Coordenador / Kristina Diane Rinker - Integrante., Financiador(es): Canadian Institute for Health Research - Bolsa.

• 2002 - 2003

  Effects Of ATP-Sensitive Potassium Channels Blockage On Renal Ischemia And Reperfusion Injury In Rats, Descrição: Projeto de iniciação científica que visa entender a importância de radicais livres e canais de potássio na ativação do fator de transcrição NF-kB na isquemia e reperfusão renal.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (0) / Especialização: (0) / Mestrado acadêmico: (0) / Mestrado profissional: (0) / Doutorado: (0) . , Integrantes: Giovanna Gomes Lara - Coordenador / Kenia pompermayer da silva - Integrante / mauro martins teixeira - Integrante.