Thiago Salum Fontana

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Projetos de pesquisa

• 2016 - 2016

  Misdiagnosis of very early frontotemporal dementia, Descrição: The aim was to discuss the misdiagnosis of FTD, having special reference to a clinical case. A 30 year-old female, married, with no previous report of mental disorders, drugs abuse, or medical illnesses was diagnosed with schizophrenia in 2013. Her father had a psychiatric disease, however not clearly explained. She was a normal person with good affective and emotional control, normal cognition and functionality before she become ill. Her family reported a three-year history of progressive behavioural disturbances (social isolation, sleep disorders, aberrant behaviours, compulsive eating of uneatable products, aggression, delusions, hallucinations, persecutory attitudes, sexual affairs and disinhibition) needing three hospitalizations since she got sick. The patient also exhibited progressive cognitive impairment mainly attributed to decay of reasoning and thinking control. Despite psychopharmacological treatment with antipsychotics, antidepressants, benzodiazepines, and anticonvulsants the patient rapidly had worsened, loosing behaviour control, executive processes, global cognition, and instrumental activities becoming dependent for all basic procedures (bathing, feeding, personal hygiene). Recently she was referred to the University Hospital for investigation. Her history, clinical examination and MRI support the diagnosis of frontotemporal dementia. The MRI displays a very prominent atrophy of frontal and temporal regions, notwithstanding the neurodegeneration had reached the whole brain. Based on clinical data and MRI the diagnosis of schizophrenia was changed to frontotemporal lobar degeneration (behaviour variant). Nowadays she remains at severe level of dementia needing complete care for bathing, eating, and personal hygiene. The clinicians had prescribed trazodona and quetiapina to control behavioural disturbances, however with limited efficacy. The main lesson from this case comprises the misidentification of early neuropsychiatric manifestations of frontotemporal dementia and the delay of reaching the accurate diagnosis.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Especialização: (2) / Mestrado acadêmico: (1) . , Integrantes: Thiago Salum Fontana - Coordenador / Julia Cunha Loureiro - Integrante / Luiz Fernando Almeida Lima e Silva - Integrante / Lucas Mella - Integrante / Florindo Stella - Integrante.

• 2013 - 2015

  Effects Of Pharmacogenetic of Risperidone on Weight Gain and Metabolic Parameters in Children and Adolescents, Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (2) Doutorado: (1) . , Integrantes: Thiago Salum Fontana - Coordenador / Paulo Dalgalarrondo - Integrante / Amilton Santos Jr - Integrante / Lucia Arisaka - Integrante / Osmar Della Torre - Integrante / Eloisa Helena Rubello Valler Celeri - Integrante.