Simone Wichert Grande

Formação complementar

Idiomas

Áreas de atuação

Participação em eventos

Produções bibliográficas

• HOBLER, CAROLIN ; ANDRADE, ANDERSON J.M. ; GRANDE, SIMONE WICHERT ; GERICKE, CHRISTINE ; Talsness, Chris E. ; APPEL, KLAUS E. ; Chahoud, Ibrahim ; Grote, Konstanze . Sex-dependent aromatase activity in rat offspring after pre- and postnatal exposure to triphenyltin chloride. Toxicology (Amsterdam) , v. 276, p. 198-205, 2010.

• Martino-Andrade, Anderson J. ; Morais, Rosana N. ; Botelho, Giuliana G. K. ; Muller, Graziela ; Grande, Simone W. ; Carpentieri, Giovanna B. ; Leão, Gabriel M. C. ; Dalsenter, Paulo R. . Coadministration of active phthalates results in disruption of foetal testicular function in rats. International Journal of Andrology , v. xx, p. xx-xx, 2009.

• Grote, Konstanze ; HOBLER, CAROLIN ; ANDRADE, ANDERSON J.M. ; GRANDE, SIMONE WICHERT ; GERICKE, CHRISTINE ; Talsness, Chris E. ; APPEL, KLAUS E. ; Chahoud, Ibrahim . Sex differences in effects on sexual development in rat offspring after pre- and postnatal exposure to triphenyltin chloride. Toxicology (Amsterdam) , v. 260, p. 53-59, 2009.

• GRANDE, S. W. ; ANDRADE, A. J. M. ; TALSNESS, C. E. ; GROTE, K. ; GOLOMBIEWSKI, A. ; STERNER-KOCK, A. ; CHAHOUD, I. . A dose response study following in utero and lactational exposure to Di-(2-ethylhexyl) phthalate (DEHP): Reproductive effects on adult female offspring rats. Toxicology , v. 229, p. 114-122, 2007.

• GROTE, K. ; HOBLER, C. ; ANDRADE, A. J. M. ; GRANDE, S. W. ; GERICKE, C. ; TALSNESS, C. E. ; APPEL, K. E. ; CHAHOUD, I. . Effects of in utero and lactational exposure to triphenyltin chloride on pregnancy outcome and postnatal development in rat offspring.. Toxicology , v. 238, p. 177-185, 2007.

• Talsness, Chris E. ; Kuriyama, Sergio N. ; Sterner-Kock, Anja ; Schnitker, Petra ; Wichert Grande, Simone ; Shakibaei, Mehdi ; Andrade, Anderson ; Grote, Konstanze ; Chahoud, Ibrahim . In utero and Lactational Exposures to Low Doses of Polybrominated Diphenyl Ether-47 Alter the Reproductive System and Thyroid Gland of Female Rat Offspring. Environmental Health Perspectives , p. 308, 2007.

• LILIENTHAL, H. ; HACK, A. ; ROTH-HARER, A. ; GRANDE, S. W. ; TALSNESS, C. E. . Effects of developmental exposure to 2,2',4,4',5-pentabromodiphenyl ether (PBDE-99) on sex steroids, sexual development, and sexually dimorphic behavior in rats. Environmental Health Perspectives , v. 114, p. 194-201, 2006.

• GROTE, K. ; ANDRADE, A. J. M. ; GRANDE, S. W. ; KURIYAMA, S. N. ; TALSNESS, C. E. ; APPEL, K. E. ; CHAHOUD, I. . Effects of peripubertal exposure to triphenyltin on female sexual development of the rat. Toxicology , v. 222, p. 17-24, 2006.

• GRANDE, S. W. ; ANDRADE, A. J. M. ; TALSNESS, C. E. ; GROTE, K. ; CHAHOUD, I. . A dose-response study following in utero and lactational exposure to di(2-ethylhexyl)phthalate: effects on female rat reproductive development. Toxicological Sciences , v. 91, p. 247-254, 2006.

• ANDRADE, A. J. M. ; GRANDE, S. W. ; TALSNESS, C. E. ; GROTE, K. ; GOLOMBIEWSKI, A. ; STERNER-KOCK, A. ; CHAHOUD, I. . A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl)phthalate (DEHP): effects on androgenic status, developmental landmarks and testicular histology in male offspring rats. Toxicology , v. 225, p. 64-74, 2006.

• ANDRADE, A. J. M. ; GRANDE, S. W. ; TALSNESS, C. E. ; GROTE, K. ; CHAHOUD, I. . A dose-response study following in utero and lactational exposure to Di-(2-ethylhexyl)phthalate (DEHP): nonmonotonic dose response and low dose effects on rat brain aromatase activity. Toxicology , v. 227, p. 185-192, 2006.

• DALSENTER, P. R. ; SANTANA, G. M. ; GRANDE, S. W. ; ANDRADE, A. J. M. ; ARAUJO, S. L. . Phthalate affect the reproductive function and sexual behavior of male Wistar rats. Human & Experimental Toxicology , v. 25, p. 297-303, 2006.

• ANDRADE, A. J. M. ; GRANDE, S. W. ; TALSNESS, C. E. ; GERICKE, C. ; GROTE, K. ; GOLOMBIEWSKI, A. ; CHAHOUD, I. . A dose response study following in utero and lactational exposure to Di-(2-ethylhexyl) phthalate (DEHP): Reproductive effects on adult male offspring rats. Toxicology , v. 228, p. 85-97, 2006.

• TALSNESS, C. E. ; SHAKIBAEI, M. ; KURIYAMA, S. N. ; GRANDE, S. W. ; STERNER-KOCK, A. ; SCHNITKER, P. ; SOUZA, C. ; GROTE, K. ; CHAHOUD, I. . Ultrastructural changes observed in rat ovaries following in utero and lactational exposure to low doses of a polybrominated flame retardant. Toxicology Letters , v. 157, p. 189-202, 2005.

• KURIYAMA, S. N. ; FIDALGO NETO, A. A. ; GRANDE, S. W. ; AKKOC, Z. ; SOUZA, C. ; CHAHOUD, I. . Thyroid hormone levels and hepatic enzyme activity in lactating dams after gestational exposure to low dose PBDE 47. Organohalogen Compounds , v. 66, p. 3901-3906, 2004.

• HIGUTI, I. H. ; GRANDE, S. W. ; SACCO, R. ; NASCIMENTO, A. J. . Isolation of Alkalophilic CGTase-Producing Bacteria and Characterization of Cyclodextrin-Glycosyltransferase. Brazilian Archives of Biology and Technology , v. 46, p. 183-186, 2003.

• GROTE, K. ; HOBLER, C. ; ANDRADE, A. J. M. ; GRANDE, S. W. ; GERICKE, C. ; APPEL, K. E. ; CHAHOUD, I. . Effects of in utero and lactational exposure to triphenyltin chloride on pregnancy outcome and postnatal development in rat offspring. In: 48th Spring Meeting Deutsche Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie., 2007, Mainz. Naunyn-Schmiedeberg's Archives of Pharmacology, 2007. v. 375. p. 79-79.

• ANDRADE, A. J. M. ; GRANDE, S. W. ; GERICKE, C. ; TALSNESS, C. E. ; GROTE, K. ; CHAHOUD, I. . The need for a new paradigm for dose selection in reproductive toxicology studies. In: 48th Spring Meeting Deutsche Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie., 2007, Mainz. Naunyn-Schmiedeberg's Archives of Pharmacology, 2007. v. 375. p. 102-102.

• GRANDE, S. W. ; ANDRADE, A. J. M. ; TALSNESS, C. E. ; GROTE, K. ; CHAHOUD, I. . Developmental exposure to high and low doses of Di-(2-ethylhexyl)phthalate (DEHP): effects on female rat offspring. In: 47th Spring Meeting Deutsche Gesellschaft für experimentelle und klinische pharmakologie und toxikologie, 2006, Mainz. Naunyn-Schmiedeberg's Archives of Pharmacology, 2006. v. 372. p. 100-100.

• ANDRADE, A. J. M. ; GRANDE, S. W. ; TALSNESS, C. E. ; GROTE, K. ; CHAHOUD, I. . Developmental exposure to high and low doses of Di-(2-ethylhexyl)phthalate (DEHP): effects on male rat offspring. In: 47th Spring Meeting Deutsche Gesellschaft für experimentelle und klinische pharmakologie und toxikologie, 2006, Mainz. Naunyn-Schmiedeberg's Archives of Pharmacology, 2006. v. 372. p. 100-101.

• HOBLER, C. ; GROTE, K. ; ANDRADE, A. J. M. ; GRANDE, S. W. ; APPEL, K. E. ; CHAHOUD, I. . Effects of triphenyltin on sexual development in female rats after in utero and postnatal exposure. In: 47th Spring Meeting Deutsche Gesellschaft für experimentelle und klinische pharmakologie und toxikologie, 2006, Mainz. Naunyn-Schmiedeberg's Archives of Pharmacology, 2006. v. 372. p. 101-101.

• GROTE, K. ; HOBLER, C. ; ANDRADE, A. J. M. ; GRANDE, S. W. ; APPEL, K. E. ; CHAHOUD, I. . Effects of triphenyltin on sexual development in male rats after in utero and postnatal exposure. In: 47th Spring Meeting Deutsche Gesellschaft für experimentelle und klinische pharmakologie und toxikologie, 2006, Mainz. Naunyn-Schmiedeberg's Archives of Pharmacology, 2006. v. 372. p. 101-101.

• TALSNESS, C. E. ; KURIYAMA, S. N. ; GRANDE, S. W. ; GROTE, K. ; CHAHOUD, I. . Low dose effects of pre-and postnatal exposure to PBDE-47 on the rat ovary. In: 47th Spring Meeting Deutsche Gesellschaft für experimentelle und klinische pharmakologie und toxikologie, 2006, Mainz. Naunyn-Schmiedeberg's Archives of Pharmacology, 2006. v. 372. p. 100-100.

• GROTE, K. ; ANDRADE, A. J. M. ; GRANDE, S. W. ; KURIYAMA, S. N. ; APPEL, K. E. ; CHAHOUD, I. . Effects of triphenyltin on sexual development and aromatase activity in pubertal female rats. In: 46th Spring Meeting Deutsche Gesellschaft für experimentelle und klinische pharmakologie und toxikologie, 2005, Mainz. Naunyn-Schmiedeberg's Archives of Pharmacology, 2005. v. 371. p. R104-R105.

• GROTE, K. ; KURIYAMA, S. N. ; FIDALGO NETO, A. A. ; GRANDE, S. W. ; AKKOC, Z. ; SOUZA, C. ; CHAHOUD, I. . Enzyme activity and thyroid hormones in lactating dams after in utero exposure to a low dose of PBDE 47. In: CREDO Cluster Workshop on Ecological Relevance of Chemically-Induced Endocrine Disruption in Wildlife, 2004, Exeter. CREDO Cluster Workshop on Ecological Relevance of Chemically-Induced Endocrine Disruption in Wildlife, 2004.

• KURIYAMA, S. N. ; FIDALGO NETO, A. A. ; GRANDE, S. W. ; RANGEL, C. ; AKKOC, Z. ; SOUZA, C. ; CHAHOUD, I. . EROD, PROD and UDPGT activity in lactating dams and offspring after in utero exposure to low dose PBDE 47. In: Low Dose Workshop on Endocrine Active Compounds, 2003, Berlin. Low Dose Workshop on Endocrine Active Compounds.

• GRANDE, S. W. ; HIGUTI, I. H. ; ZAWADSKI-BAGGIO, S. F. ; NASCIMENTO, A. J. . Studies on CGTase from alkalophilic-producing bacteria isolated in Curitiba, PR. In: XXX Reuniao Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular SBBq, 2001, Caxambu. Programas e Resumos da XXX Reuniao Anual da SBBq, 2001. p. 126.

• GRANDE, S. W. ; HIGUTI, I. H. ; NASCIMENTO, A. J. . Caracterizacao de CGTase de bactérias alcalofílicas isoladas de solo em Curitiba, PR. In: 8° Evento de Iniciacao Científica EVINCI, 2000, Curitiba. 8° EVINCI UFPR, 2000.

• GRANDE, S. W. ; SACCO, R. ; HIGUTI, I. H. ; NASCIMENTO, A. J. . Estudos sobre CGTase obtida de bactérias alcalofílicas de solo de Curitiba, Paraná, Brasil. In: 8° Reuniao Anual da Sociedade Brasileira dos Pesquisadores Nikkeis (SBPN), 2000, Curitiba. Resumos, 2000.

• GRANDE, S. W. ; NASCIMENTO, A. J. ; HIGUTI, I. H. . Characterization of CGTase from alkalophilic-producing bacteria isolated in Curitiba, PR. In: XXIX Reuniao Anual Sociedade Brasileira de Bioquímica e Biologia Molecular SBBq, 2000, Caxambu. Programas e Resumos da XXIX Reuniao Anual da SBBq, 2000.

• GROTE, K. ; HOBLER, C. ; ANDRADE, A. J. M. ; GRANDE, S. W. ; GERICKE, C. ; TALSNESS, C. E. ; APPEL, K. E. ; CHAHOUD, I. . Sex differences in effects on sexual development in rat offspring after pre- and postnatal exposure to triphenyltin chloride.. Toxicology , 2009.

Projetos de pesquisa

• 2004 - 2007

  A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): Effects on reproductive development and function of male and female offspring rats, Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Doutorado: (2) . , Integrantes: Simone Wichert Grande - Integrante / Chris E. Talsness - Integrante / Anja Sterner-Kock - Integrante / Konstanze Grote - Integrante / Ibrahim Chahoud - Coordenador / Anderson Joel Martino Andrade - Integrante / Andrea Golombiewski - Integrante., Número de produções C, T & A: 6

• 1999 - 2001

  Estudos sobre as condicoes de producao da CGTase, purificacao e caracterizacao da enzima., Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (1) . , Integrantes: Simone Wichert Grande - Integrante / Aguinaldo José do Nascimento - Coordenador / Ilma Hiroko Higuti - Integrante / Roberta Sacco - Integrante., Financiador(es): Conselho Nacional de Desenvolvimento Científico e Tecnológico - Bolsa., Número de produções C, T & A: 5