Douglas Rafaele Almeida Silveira

Pós-doutorado

Formação complementar

Idiomas

Áreas de atuação

Participação em eventos

Participação em bancas

Produções bibliográficas

• WEINHÄUSER, ISABEL ; PEREIRA-MARTINS, DIEGO A. ; ALMEIDA, LUCIANA Y. ; HILBERINK, JACOBIEN R. ; SILVEIRA, DOUGLAS R. A. ; QUEK, LYNN ; ORTIZ, CESAR ; ARAUJO, CLEIDE L. ; BIANCO, THIAGO M. ; LUCENA-ARAUJO, ANTONIO ; MOTA, JOSE MAURICIO ; HOGELING, SHANNA M. ; STERNADT, DOMINIQUE ; VISSER, NIENKE ; DIEPSTRA, ARJAN ; AMMATUNA, EMANUELE ; HULS, GERWIN ; REGO, EDUARDO M. ; SCHURINGA, JAN JACOB . M2 macrophages drive leukemic transformation by imposing resistance to phagocytosis and improving mitochondrial metabolism. SCIENCE ADVANCES , v. 9, p. 1-21, 2023.

• PEREIRA'MARTINS, DIEGO A. COELHO'SILVA, JUAN L. WEINHÄUSER, ISABEL FRANCA'NETO, PEDRO L. SILVEIRA, DOUGLAS R. ORTIZ, CÉSAR MOREIRA'AGUIAR, AMANDA LIMA, MARINUS M. KOURY, LUISA C. DE MELO, RAUL A. GLÓRIA, ANA B. FAGUNDES, EVANDRO M. LINO, BRUNO K. PAGNANO, KATIA BITTENCOURT, ROSANE NUNES, ELENAIDE TRAINA, FABIOLA FIGUEIREDO'PONTES, LORENA KEATING, ARMAND TALLMAN, MARTIN S. RIBEIRO, RAUL C. DILON, RICHARD GANSER, ARNOLD SANZ, MIGUEL A. BERLINER, NANCY , et al. VALK, PETER LÖWENBERG, BOB OTTONE, TIZIANA NOGUERA, NELIDA I. VOSO, MARIA T. PAOLONI, FRANCESCA FAZI, PAOLA AMMATUNA, EMANUELE HULS, GERWIN SCHURINGA, JAN JACOB REGO, EDUARDO M. LUCENA'ARAUJO, ANTONIO R. ; Clinical significance of mitochondrial DNA content in acute promyelocytic leukaemia. BRITISH JOURNAL OF HAEMATOLOGY , v. 200, p. 170-174, 2023.

• WEINHÄUSER, I. ; PEREIRA-MARTINS, D. A. ; HILBERINK, J. R. ; ALMEIDA, L. Y. ; SILVEIRA, D. R. A. ; QUEK, L. ; HOGELING, S. M ; MOTA, J. M. ; AMMATUNA, E. ; LUCENA-ARAUJO, A. R. ; HULS, G. A. ; REGO, E. M. ; SCHURINGA, J. J. . S252: M2-POLARIZED MACROPHAGES CONTROL LEUKEMIC STEM CELL FATE BY PROMOTING METABOLIC REPROGRAMMING. Hemasphere , v. 6, p. 153-154, 2022.

• PEREIRA-MARTINS, D. A. ; GRIESSINGER, E. ; WEINHAUSER, I. ; COELHO-SILVA, J. L. ; SILVEIRA, D. R. ; QUEK, L. ; ERDEM, A. ; HILBERINK, J. R. ; DE PAULA, E. V. ; OLALLA SAAD, S. T. ; AMMATUNA, E. ; HULS, G. ; REGO, E. M. ; LUCENA-ARAUJO, A. R. ; SCHURINGA, J. J. . P439: ASSOCIATING EX VIVO DRUG SENSITIVITY WITH METABOLIC STATUS IDENTIFIES EFFECTIVE COMBINATION STRATEGIES IN ACUTE MYELOID LEUKEMIA. Hemasphere , v. 6, p. 339-340, 2022.

• SILVEIRA, DOUGLAS RA RA ; CHATZIKYRIAKOU, PRODROMOS ; CASARES ALAEZ, MARIA DEL PILAR ; MACKIE, SARAH ; HULKS, ROAN ; YAVORSKA, OLENA ; SIEJKA-ZIELINSKA, PAULINA ; METZNER, MARLEN ; SMITH, ALASTAIR ; USUKHBAYAR, BATCHIMEG ; PENARD-LACRONIQUE, VIRGINIE ; SONG, CHUNXIAO ; GANDHI, ANITA K. ; HASAN, MAROOF ; VYAS, PARESH ; MILNE, THOMAS A. ; KRIAUCIONIS, SKIRMANTAS ; QUEK, LYNN . Dysregulation of Stem-Progenitor and Differentiation Programmes through Modulation of Bivalent Chromatin Drives Leukemogenesis in Mutant IDH2 Acute Myeloid Leukaemia. BLOOD , v. 140, p. 8698-8699, 2022.

• CHATZIKYRIAKOU, PRODROMOS ; SILVEIRA, DOUGLAS RA ; CASARES ALÁEZ, MARIA DEL PILAR ; USUKHBAYAR, BATCHIMEG ; METZNER, MARLEN ; VYAS, PARESH ; GANDHI, ANITA K. ; RISUEÑO, ALBERTO ; HASAN, MAROOF ; QUEK, LYNN . Single Cell Characterisation of Transcriptional Programmes of Responsive and Resistant Leukaemic Progenitors in -Mutant Acute Myeloid Leukaemia in the AG221-AML-005 Study. BLOOD , v. 140, p. 3414-3415, 2022.

• WEINHAEUSER, ISABEL ; PEREIRA-MARTINS, DIEGO ; YAMAMOTO DE ALMEIDA, LUCIANA ; HILBERINK, JACOBIEN R ; SILVEIRA, DOUGLAS RA ; QUEK, LYNN ; ORTIZ, CÉSAR ALEXANDER ; LUCENA-ARAUJO, ANTONIO R. ; VISSER, NIENKE ; AMMATUNA, EMANUELE ; HULS, GERWIN A. ; REGO, EDUARDO M ; SCHURINGA, JAN JACOB . M2 Macrophages Drive Resistance to Phagocytosis and Improve Mitochondrial Metabolism in Acute Myeloid Leukemia Facilitating Leukemic Transformation and Engraftment. BLOOD , v. 140, p. 1259-1260, 2022.

• PEREIRA-MARTINS, DIEGO ; VAN DIJK, NOORTJE ; WEINHAEUSER, ISABEL ; SILVEIRA, DOUGLAS RA ; COELHO DA SILVA, JUAN ; BIANCO, THIAGO M ; ORTIZ, CÉSAR ALEXANDER ; TRAINA, FABIOLA ; FIGUEIREDO-PONTES, LORENA L ; AMMATUNA, EMANUELE ; QUEK, LYNN ; HULS, GERWIN A. ; LUCENA-ARAUJO, ANTONIO R. ; REGO, EDUARDO M ; SCHURINGA, JAN JACOB . High MN1 Expression Is Associated with an Lspc-Enriched Phenotype and Glycolysis Representing a New Vulnerability in Acute Myeloid Leukemia. BLOOD , v. 140, p. 6265-6266, 2022.

• CHOWDHURY, ONIMA ; SILVEIRA, DOUGLAS RA ; REED, SOPHIE ; O'SULLIVAN, JENNIFER ; CLARK, SALLY-ANN ; ASHLEY, NEIL ; PSAILA, BETHAN ; THONGJUEA, SUPAT ; MEAD, ADAM J ; QUEK, LYNN . Single-Cell Transcriptome Analysis Reveals Pathways That Drive Dyserythropoiesis in Myelodysplastic Syndromes, Which Are Targeted By Luspatercept. BLOOD , v. 140, p. 9753-9754, 2022.

• STERNADT, DOMINIQUE ; PEREIRA-MARTINS, DIEGO ; SILVEIRA, DOUGLAS RA ; CHATZIKYRIAKOU, PRODROMOS ; CASARES ALAEZ, MARIA DEL PILAR ; WEINHAEUSER, ISABEL ; HOGELING, SHANNA M ; AMMATUNA, EMANUELE ; HULS, GERWIN A. ; QUEK, LYNN ; SCHURINGA, JAN JACOB . Impaired Metabolic Plasticity Under Stress Constitutes a Therapeutic Vulnerability in -Mutant Acute Myeloid Leukemia. BLOOD , v. 140, p. 8813-8814, 2022.

• COELHO-SILVA, JUAN L. ; SILVEIRA, DOUGLAS R. A. ; PEREIRA-MARTINS, DIEGO A. ; ROJAS, CESAR A. O. ; LUCENA-ARAUJO, ANTONIO R. ; REGO, EDUARDO M. ; MACHADO-NETO, JOÃO A. ; BENDIT, ISRAEL ; ROCHA, VANDERSON ; TRAINA, FABIOLA . Molecular-Based Score inspired on metabolic signature improves prognostic stratification for myelodysplastic syndrome. Scientific Reports , v. 11, p. 1675, 2021.

• THOMÉ, CAROLINA HASSIBE ; FERREIRA, GERMANO AGUIAR ; PEREIRA-MARTINS, DIEGO ANTONIO ; AUGUSTO DOS SANTOS, GUILHERME ; ALMEIDA-SILVEIRA, DOUGLAS R. ; WEINHÄUSER, ISABEL ; ANTÔNIO DE SOUZA, GUSTAVO ; HOUTSMA, ROOS ; SCHURINGA, JAN JACOB ; REGO, EDUARDO M. ; FAÇA, VITOR M. . The expression of NTAL and its protein interactors is associated with clinical outcomes in acute myeloid leukemia. MOLECULAR & CELLULAR PROTEOMICS , v. 21, p. 100091, 2021.

• TAVARES, RS ; CLEMENTINO, NCD ; CONCHON, MRM ; PAGNANO, KBB ; SANTANA, SA ; NASCIMENTO, ACKVD ; FUNKE, VAM ; CENTRONE, RT ; SEGURO, FS ; BORTOLINI, JAP ; SILVEIRA, DA ; Bendit, I . CLINICAL, CYTOGENETIC AND MOLECULAR CHARACTERIZATION OF BRAZILIAN COHORT PATIENTS WITH PRIMERY MYELOFIBROSIS AND MYELOFIBROSIS POST-POLYCYTTHEMIA VERA AND POST-ESSENTIAL THROMBOCYTHEMIA. Hematology Transfusion And Cell Therapy , v. 43, p. S128, 2021.

• CORTEZ, AC ; COSTA, AD ; BOVOLENTA, VDA ; NASCIMENTO, MM ; SCHMIDT-FILHO, J ; SILVEIRA, DRA . ACUTE UNDIFFERENTIATED LEUKEMIA WITH BCR-ABL TRANSLOCATION: CASE REPORT AND LITERATURE REVIEW. Hematology Transfusion And Cell Therapy , v. 43, p. S150, 2021.

• MENDES, FERNANDA RODRIGUES ; DA SILVA, WELLINGTON FERNANDES ; DA COSTA BANDEIRA DE MELO, RAPHAEL ; SILVEIRA, DOUGLAS RAFAELE ALMEIDA ; VELLOSO, ELVIRA DEOLINDA RODRIGUES PEREIRA ; ROCHA, VANDERSON ; REGO, EDUARDO MAGALHAES . Predictive factors associated with induction-related death in acute myeloid leukemia in a resource-constrained setting. ANNALS OF HEMATOLOGY , v. 100, p. 1, 2021.

• SILVEIRA, DOUGLAS RA ; CHATZIKYRIAKOU, PRODROMOS ; YAVORSKA, OLENA ; MACKIE, SARAH ; HULKS, ROAN ; SIEJKA-ZIELINSKA, PAULINA ; CORBY, ANNA ; SMITH, ALASTAIR ; BROWN, BENJAMIN ; METZNER, MARLEN ; MILNE, THOMAS A. ; PENARD-LACRONIQUE, VIRGINIE ; SONG, CHUNXIAO ; HASAN, MAROOF ; THAKURTA, ANJAN ; VYAS, PARESH ; KRIAUCIONIS, SKIRMANTAS ; QUEK, LYNN . Repressed Chromatin Drives Leukaemogenesis in Mutant IDH2 Acute Myeloid Leukaemia Via Inhibition of Granulocyte Differentiation and Cell Cycle Progression. BLOOD , v. 138, p. 3467-3467, 2021.

• WEINHÄUSER, ISABEL ; PEREIRA-MARTINS, DIEGO A ; HILBERINK, JACOBIEN R ; ALMEIDA, LUCIANA YAMAMOTO ; SILVEIRA, DOUGLAS RA ; QUEK, LYNN ; HOGELING, SHANNA M ; MOTA, JOSE MAURICIO ; AMMATUNA, EMANUELE ; LUCENA-ARAUJO, ANTONIO R. ; HULS, GERWIN A. ; SCHURINGA, JAN JACOB ; REGO, EDUARDO M . Tumor Associated Macrophages Promoted Fatal Patient Derived Acute Promyelocytic Leukemia. BLOOD , v. 138, p. 3472-3472, 2021.

• LUCENA-ARAUJO, ANTONIO R. ; PEREIRA-MARTINS, DIEGO A ; COELHO-SILVA, JUAN L ; WEINHÄUSER, ISABEL ; FRANCA-NETO, PEDRO LUIS ; SILVEIRA, DOUGLAS RA ; LIMA, MARINUS M ; SCHURINGA, JAN JACOB ; KOURY, LUISA C ; MELO, RAUL ANTÔNIO MORAIS ; BITTENCOURT, ROSANE ; PAGNANO, KATIA B ; NUNES, ELENAIDE C. ; FAGUNDES, EVANDRO MARANHÃO ; KERBAUY, FABIO R. ; FIGUEREDO-PONTES, LORENA ; REGO, EDUARDO M . Clinical Significance of Mitochondrial DNA Content in Acute Promyelocytic Leukemia. BLOOD , v. 138, p. 3474-3474, 2021.

• BEZERRA, MATHEUS F ; LIMA, ALEIDE SANTOS ; PIQUÉ-BORRÀS, MARIA-RIERA ; SILVEIRA, DOUGLAS RA ; COELHO-SILVA, JUAN LUIZ ; PEREIRA-MARTINS, DIEGO A ; WEINHÄUSER, ISABEL ; FRANCA NETO, PEDRO LUIZ ; QUEK, LYNN ; CORBY, ANNA ; OLIVEIRA, MAYARA MATIAS ; LIMA, MARINUS ; DE ASSIS, REIJANE ALVES ; DE MELO CAMPOS, PAULA ; DUARTE, BRUNO KOSA LINO ; BENDIT, ISRAEL ; ROCHA, VANDERSON ; REGO, EDUARDO M. ; TRAINA, FABIOLA ; OLALLA SAAD, SARA ; BELTRAO, EDUARDO ; BEZERRA, MARCOS ; LUCENA-ARAUJO, ANTONIO R. . Co-occurrence of DNMT3A, NPM1, FLT3 mutations identifies a subset of acute myeloid leukemia with adverse prognosis. BLOOD , v. 135, p. 870-875, 2020.

• DA SILVA, WELLINGTON FERNANDES ; DA ROSA, LIDIANE INÊS ; SEGURO, FERNANDA SALLES ; SILVEIRA, DOUGLAS RAFAELE ALMEIDA ; BENDIT, ISRAEL ; BUCCHERI, VALERIA ; VELLOSO, ELVIRA DEOLINDA RODRIGUES PEREIRA ; ROCHA, VANDERSON ; REGO, EDUARDO M . Salvage treatment for refractory or relapsed acute myeloid leukemia: a 10-year single-center experience. Clinics , v. 75, p. e1566, 2020.

• THOMÉ, CAROLINA HASSIBE FERREIRA, GERMANO AGUIAR PEREIRA-MARTINS, DIEGO ANTONIO DOS SANTOS, GUILHERME AUGUSTO ORTIZ, CÉSAR ALEXANDER DE SOUZA, LUCAS EDUARDO BOTELHO SOBRAL, LAYS MARTINS SILVA, CLEIDE LÚCIA ARAÚJO SCHEUCHER, PRISCILA SANTOS GIL, CRISTIANE DAMAS LEOPOLDINO, ANDRÉIA MACHADO SILVEIRA, DOUGLAS R. A. COELHO-SILVA, JUAN L. TRAINA, FABÍOLA KOURY, LUISA C. MELO, RAUL A. M. BITTENCOURT, ROSANE PAGNANO, KATIA PASQUINI, RICARDO NUNES, ELENAIDE C. FAGUNDES, EVANDRO M. GLORIA, ANA BEATRIZ F. KERBAUY, FÁBIO RODRIGUES CHAUFFAILLE, MARIA DE LOURDES KEATING, ARMAND , et al. TALLMAN, MARTIN S. RIBEIRO, RAUL C. DILLON, RICHARD GANSER, ARNOLD LÖWENBERG, BOB VALK, PETER LO-COCO, FRANCESCO SANZ, MIGUEL A. BERLINER, NANCY FAÇA, VITOR MARCEL REGO, EDUARDO M. ; NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia. Scientific Reports , v. 10, p. 1-12, 2020.

• SILVEIRA, DOUGLAS R. A. ; COELHO-SILVA, JUAN L. ; SILVA, WELLINGTON F. ; VALLANCE, GRANT ; PEREIRA-MARTINS, DIEGO A. ; MADEIRA, MARIA I. A. ; FIGUEREDO-PONTES, LORENA L. ; VELLOSO, ELVIRA D. R. P. ; SIMÕES, BELINDA P. ; PENIKET, ANDY ; DANBY, ROBERT ; REGO, EDUARDO M. ; VYAS, PARESH ; TRAINA, FABIOLA ; BENDIT, ISRAEL ; QUEK, LYNN ; ROCHA, VANDERSON . A multicenter comparative acute myeloid leukemia study: can we explain the differences in the outcomes in resource-constrained settings?. LEUKEMIA & LYMPHOMA , v. 61, p. 1-11, 2020.

• WEINHÄUSER, ISABEL PEREIRA-MARTINS, DIEGO A. ORTIZ, CESAR SILVEIRA, DOUGLAS R. SIMÕES, LUÍSE A. A. BIANCO, THIAGO M. ARAUJO, CLEIDE L. KOURY, LUISA C. MELO, RAUL A. M. BITTENCOURT, ROSANE I. PAGNANO, KATIA PASQUINI, RICARDO NUNES, ELENAIDE C. FAGUNDES, EVANDRO M. GLORIA, ANA B. KERBAUY, FÁBIO CHAUFFAILLE, MARIA DE LOURDES KEATING, ARMAND TALLMAN, MARTIN S. RIBEIRO, RAUL C. DILLON, RICHARD GANSER, ARNOLD LÖWENBERG, BOB VALK, PETER LO-COCO, FRANCESCO , et al. SANZ, MIGUEL A. BERLINER, NANCY AMMATUNA, EMANUELE LUCENA-ARAUJO, ANTONIO R. SCHURINGA, JAN JACOB REGO, EDUARDO M. ; Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia. Cancers , v. 12, p. 3134, 2020.

• MENDES, FERNANDA RODRIGUES ; SILVA, WELLINGTON F ; MELO, RAPHAEL BANDEIRA ; SILVEIRA, DOUGLAS R. A. ; VELLOSO, ELVIRA ; ROCHA, VANDERSON ; REGO, EDUARDO M . Assessing Early Mortality in Intensively-Treated Acute Myeloid Leukemia in a Developing Country: Genetic, Laboratory Findings, and Comorbidities Add Prognostic Information. BLOOD (PHILADELPHIA. ONLINE) , v. 136, p. 5-6, 2020.

• TRAINA, FABIOLA ; ROCHA, VANDERSON ; SILVA, WELLINGTON F. ; VYAS, PARESH ; NARDINELLI, LUCIANA ; VELLOSO, ELVIRA D. R. P. ; LUCENA-ARAUJO, ANTONIO R. ; REGO, EDUARDO M. ; PEREIRA-MARTINS, DIEGO A. ; BROWN, BENJAMIN ; SANTOS, ITAMAR S. ; SILVEIRA, DOUGLAS R. A. ; BENDIT, ISRAEL ; CORBY, ANNA ; PENIKET, ANDY ; VALLANCE, GRANT ; COELHO-SILVA, JUAN L. ; QUEK, LYNN . Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia. BLOOD ADVANCES , v. 4, p. 2339-2350, 2020.

• LUCENA-ARAUJO, ANTONIO R. COELHO-SILVA, JUAN L. PEREIRA-MARTINS, DIEGO A SILVEIRA, DOUGLAS R. KOURY, LUISA CORRÊA DE ARAUJO MELO, RAUL A. M. BITTENCOURT, ROSANE PAGNANO, KATIA PASQUINI, RICARDO NUNES, ELENAIDE C. FAGUNDES, EVANDRO M. GLORIA, ANA B. KERBAUY, FABIO R CHAUFFAILLE, MARIA DE LOURDES BENDIT, ISRAEL ROCHA, VANDERSON KEATING, ARMAND TALLMAN, MARTIN S. RIBEIRO, RAUL C. DILLON, RICHARD GANSER, ARNOLD LÖWENBERG, BOB VALK, PETER LO COCO, FRANCESCO SANZ, MIGUEL A. , et al. BERLINER, NANCY REGO, EDUARDO M. ; Combining gene mutation with gene expression analysis improves outcomes prediction in acute promyelocytic leukemia. BLOOD (PHILADELPHIA. ONLINE) , v. Jul, p. blood.2019000239, 2019.

• PEREIRA'MARTINS, DIEGO A. ; COELHO'SILVA, JUAN L. ; DOMINGOS, IGOR F. ; WEINHÄUSER, ISABEL ; SILVEIRA, DOUGLAS R. ; CUNHA, ANDERSON F. ; FRANCA'NETO, PEDRO L. ; FRANCA, RAFAEL F. ; COSTA, FERNANDO F. ; ARAÚJO, ADERSON S. ; LUCENA'ARAUJO, ANTONIO R. ; BEZERRA, MARCOS A. . Association between *5681 polymorphism (rs7170178) and osteonecrosis in haemoglobin SS-genotyped patients. BRITISH JOURNAL OF HAEMATOLOGY , v. na, p. bjh.16267, 2019.

• COELHO-SILVA, JUAN L ; SILVEIRA, DOUGLAS R. A. ; PEREIRA-MARTINS, DIEGO A ; ORTIZ ROJAS, CÉSAR ALEXANDER ; LUCENA-ARAUJO, ANTONIO R. ; REGO, EDUARDO M ; MACHADO-NETO, JOÃO AGOSTINHO ; BENDIT, ISRAEL ; ROCHA, VANDERSON ; TRAINA, FABIOLA . Molecular-Based Score Inspired on Metabolic Signature Improves Prognostic Stratification for Myelodysplastic Syndrome. BLOOD , v. 134, p. 4257-4257, 2019.

• SILVEIRA, DOUGLAS R. A. ; QUEK, LYNN ; CORBY, ANNA ; COELHO-SILVA, JUAN L ; PEREIRA-MARTINS, DIEGO A ; VALLANCE, GRANT ; BROWN, BENJAMIN ; NARDINELLI, LUCIANA ; SILVA, WELLINGTON F ; VELLOSO, ELVIRA DRP ; TRAINA, FABIOLA ; PENIKET, ANDY ; VYAS, PARESH ; REGO, EDUARDO M ; BENDIT, ISRAEL ; ROCHA, VANDERSON . Combining Clinical Features with Genetic Factors Improves Survival Prediction for Adults with Acute Myeloid Leukemia: Validation of a New Score System in 3 Cohorts. BLOOD (PHILADELPHIA. ONLINE) , v. 134, p. 2602-2602, 2019.

• SILVA, WELLINGTON F ; DA ROSA, LIDIANE INÊS ; SEGURO, FERNANDA S ; SILVEIRA, DOUGLAS R. A. ; NARDINELLI, LUCIANA ; BUCCHERI, VALERIA ; VELLOSO, ELVIRA DRP ; ROCHA, VANDERSON ; REGO, EDUARDO M . Retrospective Comparison between MEC and FLAG-Ida Regimens for Refractory or Relapsed Acute Myeloid Leukemia in Adults. BLOOD (PHILADELPHIA. ONLINE) , v. 134, p. 1354-1354, 2019.

• SILVA, WELLINGTON F. DA ; ROSA, LIDIANE INÊS DA ; MARQUEZ, GABRIEL LACERDA ; BASSOLLI, LUCAS ; TUCUNDUVA, LUCIANA ; SILVEIRA, DOUGLAS RAFAELE ALMEIDA ; BUCCHERI, VALERIA ; BENDIT, ISRAEL ; REGO, EDUARDO MAGALHÃES ; ROCHA, VANDERSON ; VELLOSO, ELVIRA D.R.P. . Real-life Outcomes on Acute Promyelocytic Leukemia in Brazil - Early Deaths Are Still a Problem. Clinical Lymphoma Myeloma & Leukemia , v. 19, p. e116-e122, 2018.

• OLIVEIRA, H. A. ; DE JESUS, A.C. F. ; PRADO, R. C. P. ; SANTOS, A. C. E. ; SOBRAL, P. M. S. ; OLIVEIRA, A. M. P. ; MARCENA, S. M. L. ; SILVEIRA, D. R. A. . Synovial cyst of the thoracic spine: case report. ARQUIVOS DE NEURO-PSIQUIATRIA , v. 65, p. 838-840, 2007.

• SILVEIRA, D. R. A. ; CARVALHO, J. F. . Dor Lombar Aguda. In: Álvaro Nagib Atallah; Dario Birolini. (Org.). Atualização Terapêutica: Urgências e Emergências. 1ed.São Paulo: Artes Médicas, 2012, v. 1, p. 480-484.

• SILVEIRA, D. R. A. ; MACHADO, L. S. G. ; SATO, E. I. . Artrite Aguda. In: Álvaro Nagib Atallah; Dário Birolini. (Org.). Atualização Terapêutica: Urgências e Emergências. 1ed.São Paulo: Artes Médicas, 2012, v. 1, p. 484-487.

• SILVEIRA, D. R. A. ; QUEK, L ; COELHO-SILVA, JUAN L. ; PEREIRA-MARTINS, DIEGO A ; SILVA, WELLINGTON F. DA ; TRAINA, F. ; VELLOSO, ELVIRA D.R.P. ; REGO, EDUARDO M. ; ROCHA, VANDERSON ; BENDIT, ISRAEL . A MULTICENTRE RETROSPECTIVE STUDY ON ACUTE MYELOID LEUKAEMIA IN ADULTS: EARLY DEATH AND LOW RATE OF BONE MARROW TRANSPLANTATION STILL COMPROMISE THE OUTCOME. In: Congresso Brasileiro de Hematologia, Hemoterapia e Terapia Celular - Hemo, 2019, Rio de Janeiro. Hematology,Transfusion and Cell Therapy. Rio de Janeiro: Elsevier, 2019. v. 41. p. 177-177.

• COELHO-SILVA, JUAN L. ; SILVEIRA, D. R. A. ; PEREIRA-MARTINS, DIEGO A ; LUCENA-ARAUJO, ANTONIO R. ; REGO, EDUARDO M. ; BENDIT, ISRAEL ; ROCHA, VANDERSON ; TRAINA, F. . ESCORE DE RISCO MOLECULAR INSPIRADO EM ASSINATURA METABÓLICA REFINA O PROGNÓSTICO DE PACIENTES COM SÍNDROMES MIELODISPLÁSICAS. In: Congresso Brasileiro de Hematologia, Hemoterapia e Terapia Celular - Hemo, 2019, Rio de Janeiro. Hematology,Transfusion and Cell Therapy. Rio de Janeiro: Elsevier, 2019. v. 41. p. 219-219.

• COELHO, J. M. ; SILVEIRA, D. R. A. ; CUNHA, W. S. ; LEOPOLDINO, J. F. S. . DIAGNÓSTICO PRECOCE DE NEUROTOXICIDADE POR DROGAS NO TRATAMENTO DO CÂNCER ? REGISTRO DE ONDAS F. In: Congresso Brasileiro de Hematologia, Hemoterapia e Terapia Celular - Hemo, 2019, Rio de Janeiro. Hematology,Transfusion and Cell Therapy. Rio de Janeiro: Elsevier, 2019. v. 41. p. 567-567.

• BRUCE, D. ; BURNS, A. ; ROBBE, P. ; APPLEBY, N. ; KLINTMANN, J. ; SILVEIRA, D. R. A. ; MEAD, A. J. ; SCHUH, A. . INTERROGATION OF HAEMATOPOIETIC BONE MARROW PROGENITORS FOR DRIVER MUTATIONS OF CHRONIC LYMPHOCYTIC LEUKAEMIA. In: EHA 2018, 2018, Stockholm. HemaSphere, 2018. p. 110-111.

• BITTENCOURT, M. C. ; RAMOS, JF ; ATANAZIO, M. J. ; SILVEIRA, D. R. A. ; COSTA, S. F. ; SCHMIDT-FILHO, J. ; ROCHA, V. . REATIVAÇÃO DE CITOMEGALOVÍRUS EM PACIENTES TRANSPLANTADOS DE CÉLULAS-TRONCO HEMATOPOIÉTICAS COM DEPLEÇÃO IN VIVO DE LINFÓCITOS T. In: SBTMO, 2017, São Paulo. Anais Congresso SBTMO 2017, 2017. v. 1. p. 68-68.

• SILVEIRA, D. R. A. ; DORIA, F. M. ; PERCOUT, P. O. ; MONTEIRO, J. A. ; CHAVES, L. P. B. . ACUTE PROMYELOCYTIC LEUKEMIA WITH RARE THROMBOTIC PRESENTATION: A CASE REPORT. In: XI Congresso Panamericano e Ibérico de Medicina Crítica e Terapia Intensiva, VIII Congresso Panamericano e Ibérico de Enfermeria Intensiva e XXI Congresso Brasileiro de Medicina Intensiva, 2016, Porto Alegre. Anais do XI Congresso Panamericano e Ibérico de Medicina Crítica e Terapia Intensiva, VIII Congresso Panamericano e Ibérico de Enfermeria Intensiva e XXI Congresso Brasileiro de Medicina Intensiva, 2016.

• Girardi, DM ; SILVEIRA, D. R. A. ; Fonseca, LG ; Souza, CE ; Bastos, DA . Hemofilia adiquirida em paciente com câncer de Próstata. In: Congresso Brasileiro de Oncologia Clínica, 2015, Foz do Iguaçu. HEMOFILIA A ADQUIRIDA EM PACIENTE COM CÂNCER DE PROSTATA: RELATO DE CASO, 2015.

• VASCONCELOS, D. P. ; SILVEIRA, D. R. A. ; SANTANA, I. A. ; CIPOLOTTI, R. ; RANGEL, M. R. U. . Linfoma de Burkitt de Seios Paranasais. In: X Congresso Brasileiro de Oncologia Pediátrica, 2006, Salvador. X Congresso Brasileiro de Oncologia Pediátrica, 2006. p. 107-107.

• VASCONCELOS, D. P. ; SILVEIRA, D. R. A. ; ARAGÃO, J. A. ; REIS, F. P. ; CARDOSO, S. M. M. ; MADRUGA, R. E. T. T. A. ; FEITOSA, V. L. C. . Estudo Anatômico do Ligamento Patelofemoral Medial. In: VI congresso de Iniciação Científica - UFS/CNPq, 2004, São Cristóvão. VI Congresso de Iniciação Científica, 2004. p. 279-279.

• VASCONCELOS, D. P. ; SILVEIRA, D. R. A. ; ARAGÃO, J. A. ; REIS, F. P. ; CARDOSO, S. M. M. ; MADRUGA, R. E. T. T. A. ; FEITOSA, V. L. C. . Estudo Anatomico do Ligamento Patelofemoral Medial. In: Reunião de integração da Morfologia Panamericana (XXI Congresso Brasileiro de Anatomia), 2004, Foz do Igiaçu. Anais da Reunião de Integração da Morfologia Pan-americana, 2004.

• SILVEIRA, DRA . Personalised medicine on myeloid malignancies: from diagnosis to treatment. 2021. (Apresentação de Trabalho/Conferência ou palestra).

• SILVEIRA, D. R. A. ; QUEK, L ; COELHO-SILVA, JUAN L. ; PEREIRA-MARTINS, DIEGO A ; SILVA, WELLINGTON F. DA ; TRAINA, F. ; VELLOSO, ELVIRA D.R.P. ; REGO, EDUARDO M. ; ROCHA, VANDERSON ; BENDIT, ISRAEL . A MULTICENTRE RETROSPECTIVE STUDY ON ACUTE MYELOID LEUKAEMIA IN ADULTS: EARLY DEATH AND LOW RATE OF BONE MARROW TRANSPLANTATION STILL COMPROMISE THE OUTCOME. 2019. (Apresentação de Trabalho/Congresso).

• SILVEIRA, D. R. A. . Genética Molecular da Leucemia Linfocítica Crônica. 2016. (Apresentação de Trabalho/Conferência ou palestra).

• SILVEIRA, D. R. A. . Aspectos Moleculares da Doença Residual Mínima na Leucemia Linfocítica Crônica. 2016. (Apresentação de Trabalho/Conferência ou palestra).

• SILVEIRA, D. R. A. . The Biology and Clinical Impact of Genetic Lesions in Myeloid Malignances. 2014. (Apresentação de Trabalho/Conferência ou palestra).

• SILVEIRA, D. R. A. . Optimal use of bisphosphonates in patients with multiple myeloma. 2013. (Apresentação de Trabalho/Conferência ou palestra).

• SILVEIRA, D. R. A. . Trombocitopenia na gestação: trombocitopenia imune ou...?. 2013. (Apresentação de Trabalho/Conferência ou palestra).

• VAHLE, V. A. ; TELES DE MENDONCA, J. ; SILVEIRA, D. R. A. ; VASCONCELOS, D. P. . Angioplastia Coronariana Eletiva: Resultados em 1 ano 2007 2007 (Trabalho de Conclusão de Curso (Co - Autoria)).

• VASCONCELOS, D. P. ; ARAGÃO, J. A. ; SILVEIRA, D. R. A. ; REIS, F. P. ; VAHLE, V. A. . Estudo do Ligamento Patelofemoral Medial 2007 (Trabalho de Conclusão de Curso (Co - Autoria)).

Projetos de pesquisa

• 2021 - Atual

  Clonal haemopoiesis in the ageing population and myeloid bone marrow disorders, Descrição: This is a prospective, longitudinal, cohort study to understand clonal hemopoiesis (CH) and immune modulation in the healthy ageing population, and in myeloid neoplasms and bone marrow failure. CH is where clinically healthy individuals are found to have acquired genetic mutations in their blood and bone marrow. Some of these mutations are associated with an increased risk of blood and other disorders. The estimated incidence of CH in those older than 65 years is ~10-15%. This project, which is a collaboration between King?s and Bristol Myers Squibb, is aimed at understanding changes to the genomic, haematopoeitic, and immune landscape in CH and how these may affect the development of blood cancers and cardiovascular disease.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Douglas Rafaele Almeida Silveira - Integrante / QUEK, LYNN - Coordenador.

• 2020 - Atual

  Epigenetic regulation of differentiation of IDH-mutant AML, Descrição: We work with acute myeloid leukemia (AML) samples donated by patients to better understand the biology of AML with mutations in isocitrate dehydrogenase (IDH) 1 and 2 (~20% of AMLs). Inhibitors of mutant IDH enzymes can be effective in treating AML by inducing differentiation of leukaemic cells into mature blood cells. This project is to dissect the epigenetic mechanisms of regulation of transcriptional pathways which are altered by IDH inhibitors to promote differentiation, where we hope to find new ways to reprogramme AML cells to function normally. This work is funded by UKRI/MRC.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Douglas Rafaele Almeida Silveira - Integrante / Lynn Quek - Coordenador.

• 2018 - Atual

  IDH2 AML, Descrição: It is a translational project using Single-cell multiomics next-generation sequencing to interrogate which molecular pathways either genomic, transcriptomic, or epigenomic are altered and what changes occur after AG-221 treatment for patients with AML IDH2 mutated. The project involves human samples, cell lines and in-vitro experiments.. , Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Doutorado: (1) . , Integrantes: Douglas Rafaele Almeida Silveira - Integrante / Lynn Quek - Coordenador / Anna Corby - Integrante.

• 2016 - 2020

  Estudo Multicêntrico em Leucemias Mielóides Agudas, Descrição: Estudo retrospectivo multicêntrico, São Paulo, Ribeirão Preto e Oxford, utilizando modelagem estatística para encontrar novos fatores prognósticos, validar variáveis conhecidas e idealizar classificações e escores que possam melhorar a acurácia da predição prognóstica. Também envolve genotipagem ampla das coortes e análise de sobrevida comparativa.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Doutorado: (4) . , Integrantes: Douglas Rafaele Almeida Silveira - Coordenador / Israel Bendit - Integrante / Lynn Quek - Integrante / SILVA, WELLINGTON F. DA - Integrante / ROCHA, VANDERSON - Integrante / Paresh Vyas - Integrante / Anna Corby - Integrante / COELHO-SILVA, JUAN L. - Integrante / PEREIRA-MARTINS, DIEGO A - Integrante / REGO, EDUARDO M. - Integrante / Fabiola Traina - Integrante., Número de produções C, T & A: 10

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