Kazutaka Fukushima

Possui graduação pela Faculdade de Farmácia - Nagasaki University (1965), Mestrado - Nagasaki University (1967) e Doutorado em Farmácia - University Of Tokyo (1984). Atualmente, é professor Titular do Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, onde desenvolve projetos de pesquisa e orientações nas área de Biotecnologia e Microbiologia, com ênfase em Microbiologia Aplicad, Química de Metabólitos Secundários e Biologia Molecular. Já publicou mais de 130 trabalhos em diferentes periódicos com excelente política de publicação, como também, tem sido referee. Durante a sua vida acadêmica se dedica também à orientação de estudantes de pós-graduação Mestrado e Doutorado (mais de 25) e supervisão de pós-doutorandos. As parcerias acadêmicas e de pesquisas estão sendo realizadas com o Brasil (cerca de 20 anos), China, Coréia, Canadá e Estados Unidos (mais de 10 anos ), Espanha (cerca de 6 anos ), Italia ( cerca de 5 anos ), Holanda ( cerca de 4 anos) e Alemanha (cerca de 3 anos). Recentemente, está como professor visitante pelo CNPq durante seis meses, atuando no Mestrado em Desenvolvimento de Processos Ambientais, Núcleo de Pesquisas em Ciências Ambientais-NPCIAMB da Universidade Católica de Pernambuco.Participa ainda do Doutorado em Biotecnologia da Rede Nordeste de Biotecnologia-RENORBIO, pela Universidade Católica de Pernambuco, vinculado ao Ponto Focal Universidade Federal Rural de Pernambuco.

Informações coletadas do Lattes em 16/06/2022

Acadêmico

Formação acadêmica

Doutorado em Pharmacy

1981 - 1984

University Of Tokyo
Título: The structural studies on the antifungal antibiotics, leucinostatins A and B, and copiamycin
Orientador: Shigenobu Okuda

Mestrado em Master Course

1965 - 1967

Nagasaki University
Orientador: Prof Hyozo Toniyama

Graduação em Graduated from the Faculty of Pharmacy,

1961 - 1965

Nagasaki University
Orientador: Prof. Hyozo Taniyama

Idiomas

Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Português

Compreende Razoavelmente, Fala Razoavelmente, Lê Razoavelmente, Escreve Razoavelmente.

Japonês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Áreas de atuação

Grande área: Ciências Biológicas / Área: Microbiologia / Subárea: Biotecnologia.

Grande área: Ciências Biológicas / Área: Microbiologia / Subárea: Micologia.

Grande área: Ciências Biológicas / Área: Microbiologia / Subárea: Microbiologia Aplicada.

Grande área: Ciências Biológicas / Área: Microbiologia / Subárea: Biologia e Fisiologia dos Microorganismos.

Grande área: Engenharias / Área: Engenharia Química / Subárea: Processos Industriais de Engenharia Química/Especialidade: Processos Bioquímicos.

Produções bibliográficas

SHIOSAKI, R. K. ; ALBUQUERQUE, C. D. C. ; OKADA, K. ; FUKUSHIMA, K. ; CAMPOS-TAKAKI, G. M. . Monitoring the Effect of Pyrene on the Germination and Radial Growth of the Wild and Mutant Strains of Rhizopus arrhizus UCP402. Brazilian Archives of Biology and Technology , v. 51, p. 613-621, 2008.
WAKANA, D. ; HOSOE, T. ; ITABASHI, T. ; OKADA, H. ; FUKUSHIMA, K. ; KAWAI, I. . Structures of new triterpene glycosides, Malbrancheosides A-D, from Malbranchea filamentosa. Heterocycles (Tokyo) , v. 75, p. 1109-1122, 2008.
WAKANA, D. ; HOSOE, T. ; ITABASHI, T. ; FUKUSHIMA, K. ; KAWAI, I. . Two new furanone gd. lycosides, malfilamentosides A and B, from Malbranchea filamentosa. Maikotokishin , v. 58, p. 1-6, 2008.
Takashi Yaguchi ; TAKIZAWA, K. ; TAGUCHI, H. ; TANAKA, R. ; KUBOTA, T. ; KUBOTA, Y. ; KUBOTA, M. ; FUKUSHIMA, K. . Antifungal activity of the novel adduct, GX-95, of silver with nanometer-scale particles to peptidic hydrolysates from collagen.. Nihon Ishinkin Gakkai Zasshi , v. 48, p. 97-100, 2007.
ZENG, JS ; FUKUSHIMA, K. ; TAKIZAWA, K. ; ZENG, Y.C. ; NISHIMURA, K. ; GRAESER, Y. ; DO HOOG S. . Intraspecific diversity of species of Pseudallescheria boydii complex. Medical Mycology (Oxford) , v. 45, p. 547-558, 2007.
NAKADATE, S. ; NOZAWA, K. ; HORIE, H. ; FUJII, Y. ; NAGAI, M. ; HOSOE, T. ; KAWAI, I. ; YAGUCHI, T. ; FUKUSHIMA, K. . Decalin derivatives from Eupenicilium javanicum. Journal of Natural Products , v. 70, p. 1510-1512, 2007.
PARIDE, A. ; FUKUSHIMA, K. ; DENG, S.W. ; TAKIZAWA, K. . Molecular typing of Trichophyton shoenleinii isolated in Xinjiang, China by PCR-RAPD. Chin J Dermatol , v. 40, p. 499-506, 2007.
ZENG, JS ; Fukushima, Kazutaka ; ZENG, Y.C. ; TAKIZAWA, K. ; NISHIMURA, K. . Comparison among inoculum forms of Pseudallescheria boydii isolates on antifungal susceptibility to three azole agents in vitro. Indian Journal of Leprosy , v. 23, p. 12-17, 2007.
Moretti, Annabella ; Fukushima, Kazutaka ; Takizawa, Kayoko ; Suzuki, Motofuni ; Vidotto, Valerio ; Cannizzo, Francesca T. ; Boncio, Luisa ; Bollo, Enrico . First report of oral colonization by Debaryomyces nepalensis in a dog. Mycopathologia , v. 164, p. 189-192, 2007.
Moretti, Annabella ; Fukushima, Kazutaka ; Takizawa, Kayoko ; Suzuki, Motofuni ; Vidotto, Valerio ; Cannizzo, Francesca T. ; Boncio, Luisa ; Bollo, Enrico . First report of oral colonization by Debaryomyces nepalensis in a dog. Mycopathologia , v. 164, p. 189-192, 2007.
HOSOE, T. ; WAKANA, D. ; NOZAWA, K. ; OKADA, K. ; CAMPOS-TAKAKI, G. M. ; TAKIZAWA, K. ; Takashi Yaguchi ; FUKUSHIMA, K. . Antifungal substances isolated from Aspergillus fumigatus IFM 54246, obtained from a Brazilian soil. Maikotokishin , v. 56, p. 07-10, 2006.
WAKANA, D. ; HOSOE, T. ; ITABASHI, T. ; NOZAWA, K. ; OKADA, K. ; CAMPOS-TAKAKI, G. M. ; YAGUCHI, T. ; FUKUSHIMA, K. ; KAWAI, K. . Isolation of isoterrein from Neosartorya fischeri. FEMS Microbiology Letters , v. 56, p. 3-6, 2006.
XI, L. ; LU, C. ; FUKUSHIMA, K. ; TAKIZAWA, K. ; NISHIMURA, K. ; XIE, S. . Evaluation on biological aspects of twenty clilnical isolates of Cryptococcus neoformans var. neoformans. Chin J Zoonoses , v. 22, p. 946-948, 2006.
HOSOE, T. ; FUKUSHIMA, K. ; TAKIZAWA, K. ; ITABASHI, T. ; YOZA, K. ; KAWAI, K. . A new pyrrolidone-2, 4-dione derivative, vermelhotin, isolated from unidentified fungus IFM 52642. Heterocycles (Tokyo) , v. 68, p. 1949-1953, 2006.
WAKANA, D. ; HOSOE, T. ; ITABASHI, T. ; OKADA, K. ; CAMPOS-TAKAKI, G. M. ; FUKUSHIMA, K. ; KAWAI, K. . New citrinin derivatives isolated from Penicillium citrinum. Journal of Natural Medicines , v. 60, p. 279-284, 2006.
NAKADATE, S. ; NOZAWA, K. ; HORIE, H. ; FUJII, Y. ; NAGAI, M. ; KOMAI, S. ; HOSOE, T. ; KAWAI, K. ; YAGUCHI, T. ; FUKUSHIMA, K. . New dioxomorpholine derivatives, javanicunine A and B, from Eupenicillium javanicum. Heterocycles (Tokyo) , v. 68, p. 1969-1972, 2006.
HOSOE, T. ; FUKUSHIMA, K. ; TAKIZAWA, K. ; VIDOTTO, V. ; KAWAI, K. . A new antifungal macrolide, eushearilide, isolated from Eupenicillium shearii. Journal of Antibiotics (Tokyo) , v. 59, p. 597-600, 2006.
VIDOTTO, V. ; ITO-KUWA, S. ; AOKI, S. ; FUKUSHIMA, K. ; Bollo, Enrico . Extracellular enzymatic activities in Cryptococcus neoformans strains isolated from AIDS patients in different countries. Revista Iberoamericana de Micología , v. 23, p. 216-220, 2006.
MELO, N.R. ; VILELA, M.M.S. ; JORGE, J.Jr. ; KAMEI, K. ; MIYAJI, M. ; Fukushima, Kazutaka ; NISHIMURA, K. ; GROENEVELD, P. ; KELLY, S.L. ; TAGUCHI, H. . HIV-1 anti-retroviral drug effect on the C. albicans hyphal growth rates by a Bio-cell tracer system. Brazilian Journal of Microbiology , v. 37, p. 225-229, 2006.
KOMAI, S. ; HOSOE, T. ; ITABASHI, T. ; NOZAWA, K. ; YAGUCHI, T. ; FUKUSHIMA, K. ; KAWAI, K. . New penicillide derivatives isolated from Penicillium simplicissimum. Journal of Natural Medicines , v. 60, p. 185-190, 2006.
Melo, Nadja Rodrigues de ; Taguchi, Hideaki ; Culhari, Vitoria V.P. ; Sano, Ayako ; Fukushima, Kazutaka ; Miyaji, Makoto ; Manning, Nigel ; Kelly, Steven L. ; Vilela, Marluce S. . Candida dubliniensis in a Brazilian family with an HIV 1- infected child: identification, antifungal susceptibility, drug accumulation and sterol composition. Brazilian Journal of Microbiology , v. 37, p. 237, 2006.
PARK, B ; PARK, J ; Taguchi, H ; Fukushima, K ; HYON, S ; TAKATORI, K . Antifungal susceptibility of epigallocatechin 3-O-gallate (EGCg) on clinical isolates of pathogenic yeasts. Biochemical and Biophysical Research Communications , v. 347, p. 401-405, 2006.
Abliz, P. ; FUKUSHIMA, K. ; TAKIZAWA, K. ; NISHIMURA, K. . Specific Oligonucleotide Primers for Identification of Cladophialophora carrionii, a Causative Agent of Chromoblastomycosis. Journal of Clinical Microbiology , v. 42, p. 404-407, 2004.
FRANCO, L. O. ; Maia, Rita de Cássia C. ; Porto, Ana Lúcia F. ; Messias, Arminda Sacconi ; Fukushima, Kazutaka ; CAMPOS-TAKAKI, G. M. . Heavy metal biosorption by chitin and chitosan isolated from Cunninghamella elegans (IFM 46109). Brazilian Journal of Microbiology , v. 35, p. 243, 2004.
Xi, L. ; FUKUSHIMA, K. ; LU, C. ; TAKIZAWA, K. ; LIAO, R. ; NISHIMURA, K. . First Case of Arthrographis kalrae Ethmoid Sinusitis and Ophthalmitis in the People's Republic of China. Journal of Clinical Microbiology , v. 42, p. 4828-4831, 2004.
Abliz, P ; FUKUSHIMA, K. ; TAKIZAWA, K. ; NISHIMURA, K. . Identification of pathogenic dematiaceous fungi and related taxa based on large subunit ribosomal DNA D1/D2 domains sequence analysis. FEMS Immunology and Medical Microbiology , v. 40, p. 41-49, 2004.
KOMAI, S. ; HOSOE, T. ; ITABASHI, T. ; NOZAWA, K. ; OKADA, K. ; CAMPOS-TAKAKI, G. M. ; CHIKAMORI, M. ; YAGUCHI, T. ; FUKUSHIMA, K. ; MIYAJI, M. ; KAWAI, K. . A new funicone derivative isolated from Talaromyces flavus. Maikotokishin , v. 54, p. 15-19, 2004.
Abliz, P ; SOUZA-MOTA, C. M. ; DENG, S.W. ; MAGALAOS, O. M. ; Xi, L. ; VIDOTTO, V. ; TAKIZAWA, K. ; NISHIMURA, K. ; FUKUSHIMA, K. . Molecular typing of Trichophyton tonsurans by PCR-RFLP of the ribosomal DNA nontranscribed spacer region.. Journal of Dermatological Science , v. 36, p. 125-127, 2004.
Melo, NR ; Taguchi, H ; Jorge, J ; Pedro, RJ ; Almeida, OP ; Fukushima, K ; Nishimura, K ; Miyaji, M . Oral Candida flora from Brazilian human immunodeficiency virus-infected patients in the highly active antiretroviral therapy era. Memórias do Instituto Oswaldo Cruz , v. 99, p. 425, 2004.
Abliz, P. ; FUKUSHIMA, K. ; TAKIZAWA, K. ; NIEDA, N. ; Miyaji, Makoto ; NISHIMURA, K. . Rapid Identification of the Genus Fonsecaea by PCR with Specific Oligonucleotide Primers. Journal of Clinical Microbiology , v. 41, p. 873-876, 2003.
Tsui, C. K. M. ; Hyde, K. D. ; FUKUSHIMA, K. . Fungi on submerged wood in the Koito River, Japan. Mycoscience (Tokyo) , v. 44, p. 55-59, 2003.
Horie, Yoshikazu ; Abliz, P. ; Fukushima, Kazutaka ; OKADA, K. ; Takaki, G.M. Campos . Two new species of Neosartorya from Amazonian soil, Brazil. Mycoscience (Tokyo) , v. 44, p. 397-402, 2003.
Lima, Marcos Antonio Barbosa de ; Nascimento, Aline Elesbão do ; Souza, Wanderley de ; Fukushima, Kazutaka ; CAMPOS-TAKAKI, G. M. . Effects of phosphorus on polyphosphate accumulation by Cunninghamella elegans. Brazilian Journal of Microbiology , v. 34, p. 363, 2003.
Abliz, P ; FUKUSHIMA, K. ; TAKIZAWA, K. ; MIYAJI, M. ; NISHIMURA, K. . Specific oligonucleotide primers for identification of Hortaea werneckii, a causative agent of tinea nigra. Diagnostic Microbiology and Infectious Disease , v. 46, p. 89-93, 2003.
Takahashi, Y. ; SANO, A. ; TAKIZAWA, K. ; Fukushima, Kasutaka ; MIYAJI, M. ; NISHIMURA, K. . The epidemiolgy and mating behavior of Arthroderma benhaniae var. erinacei in household four-toed hedgehogs (Atelerix albiventris) in Japan.. Nihon Ishinkin Gakkai Zasshi , v. 44, p. 31-38, 2003.
Andrade, Vânia Sousa ; BARROS NETO, B. ; FUKUSHIMA, K. ; CAMPOS-TAKAKI, G. M. . Effect of medium components and time of cultivation on chitin production by Mucor circinelloides (Mucor javanicus IFO 4570)- a factory study. Revista Iberoamericana de Micología , v. 20, p. 149-153, 2003.
Andrade, Vânia Sousa ; Sarubbo, Leonie Asfora ; Fukushima, Kasutaka ; Miyaji, Makoto ; Nishimura, Kazuko ; CAMPOS-TAKAKI, G. M. . Production of extracellular proteases by Mucor circinelloides using D-glucose as carbon source / substrate. Brazilian Journal of Microbiology , v. 33, p. 106, 2002.
Abliz, P ; FUKUSHIMA, K. ; TAKIZAWA, K. ; YANG, R. ; LI, R. ; NISHIMURA, K. . Identification of the first isolates of Trichosporon asahii var. asahii from disseminated trichosporonosis in China. Diagnostic Microbiology and Infectious Disease , v. 44, p. 17-22, 2002.
Takahashi, Y. ; HARITANI, K. ; SANO, A. ; TAKIZAWA, K. ; Fukushima, Kasutaka ; MIYAJI, M. ; NISHIMURA, K. . An Isolate of Arthroderma benhamiae with Trichophyton mentagrophytes var. erinacei anamorph isolated from a four-toed hedgehog (Atelerix albiventris) in Japan. Nihon Ishinkin Gakkai Zasshi , v. 43, p. 249-255, 2002.
HARITANI, K. ; TANAKA, R. ; Abliz, P. ; TAKIZAWA, K. ; SANO, A. ; Fukushima, Kazutaka ; NISHIMURA, K. ; MIYAJI, M. . The first isolation of Hortaea werneckii from a household guinea pig. Nihon Ishinkin Gakkai Zasshi , v. 43, p. 175-180, 2002.
Horie, Yoshikazu ; Abliz, P. ; Fukushima, Kazutaka ; OKADA, K. ; Gusmão, Norma B. . Neosartorya takakii, a new species from soil in Brazil. Mycoscience (Tokyo) , v. 42, p. 91-95, 2001.
Amorim, R. V. S. ; Souza, Wanderley de ; Fukushima, Kazutaka ; CAMPOS-TAKAKI, G. M. . Faster chitosan production by mucoralean strains in submerged culture. Brazilian Journal of Microbiology , v. 32, p. 20, 2001.
Kim, J. A. ; Takahashi, Y. ; TANAKA, R. ; FUKUSHIMA, K. ; NISHIMURA, K. ; MIYAJI, M. . Identification and subtyping of Trichophyton mentagrophytes by random amplified polymorphic DNA. Mycoses (Berlin) , v. 44, p. 157-165, 2001.
Calvo, B. M. ; COLOMBO, A. L. ; FISCHMAN, O. ; SANTIAGO, A. ; THOMPSON, L. ; LAZERA, M. ; TELLES, F. ; Fukushima, Kazutaka ; Nishimura, Kazuko ; TANAKA, R. ; Miyaji, Makoto ; MORETTI-BRANCHINI, M. L. . Antifungal Susceptibilities, Varieties, and Electrophoretic Karyotypes of Clinical Isolates of Cryptococcus neoformans from Brazil, Chile, and Venezuela. Journal of Clinical Microbiology , v. 39, p. 2348-2350, 2001.
SANO, A. ; YOKOYAMA, K. ; TAMURA, M. ; Takashi Yaguchi ; Fukushima, Kasutaka ; Miyaji, Makoto ; NISHIMURA, K. . Detection of gp43 and ITS1-5.8S-ITS2 ribosomal RNA genes of Paracoccidioides brazsliensis in paraffin-enbedded tissue. Nihon Ishinkin Gakkai Zasshi , v. 42, p. 23-27, 2001.
Alves, S ; MILAN, E. P. ; MORETTI-BRANCHINI, M. L. ; NISHIMURA, K. ; FUKUSHIMA, K. ; OLIVEIRA, L. O. ; COSTA, J. M. ; COLOMBO, A. L. . First isolation of Candida dubliniensis in Rio Grande do Sul, Brazil. Diagnostic Microbiology and Infectious Disease , v. 39, p. 165-168, 2001.
Moretti-Branchini, M ; Fukushima, Kasutaka ; SCHREIBER, A. ; NISHIMURA, K. ; PARALORDANOU, P. ; TRABASSO, P. ; TANAKA, R. ; MIYAJI, M. . Trichosporon species infection in bone marrow transplanted patients. Diagnostic Microbiology and Infectious Disease , v. 39, p. 161-164, 2001.
UNO, J. ; TANAKA, R. ; MORETTI-BRANCHINI, M. L. ; AOKI, S. ; YARITA, K. ; SANO, A. ; Fukushima, Kasutaka ; Mikami, Yuzuru ; NISHIMURA, K. ; MIYAJI, M. . An atypical Cryptococcus neoformans isolate from HIV-infected patient in Brazil. Nihon Ishinkin Gakkai Zasshi , v. 42, p. 127-132, 2001.
SHIOSAKI, R. K. ; OKADA, K. ; Gusmão, Norma B. ; NIGA, P. ; FALCAO, P. S. ; SILVA, N. H. ; Fukushima, Kasutaka ; NISHIMURA, K. ; MIYAJI, M. ; CAMPOS-TAKAKI, G. M. . Biochemical markers in taxonomy of Cunninghamella genus. Revista Iberoamericana de Micología , v. 18, p. 123-127, 2001.
HOSOE, T. ; OKAMOTO, S. ; NOZAWA, K. ; KAWAI, K. ; OKADA, K. ; CAMPOS-TAKAKI, G. M. ; Fukushima, Kasutaka ; MIYAJI, M. . New pentanorlanostane derivatives, cladosporides B-D, as characteristic antifungal agents against Aspergillus fumigatus, isolated from Cladosporium sp.. Journal of Antibiotics (Tokyo) , v. 54, p. 747-750, 2001.
Imazu, Michio ; Azbukina, Zinaida M. ; Kakishima, Makoto ; Fukushima, Kazutaka ; Nishimura, Kazuko ; Miyaji, Makoto . Identification of a rust fungus onPinus pumila collected in the North Kurils, Russia. Mycoscience (Tokyo) , v. 41, p. 139-144, 2000.
SANO, A. ; SANTOS-VILELA, M. M. ; Takahashi, Y. ; FUKUSHIMA, K. ; TAKIZAWA, K. ; SILVA, M. T. N. ; UNO, J. ; NISHIMURA, K. ; Miyaji, Makoto . Isolation of Candida dubliniensis from the oral cavity of an HIV-positive child in Brazil. Nihon Ishinkin Gakkai Zasshi , v. 41, p. 177-181, 2000.
HOSOE, T. ; OKADA, H. ; ITABASHI, T. ; NOZAWA, K. ; OKADA, K. ; CAMPOS-TAKAKI, G. M. ; FUKUSHIMA, K. ; Miyaji, Makoto ; KAWAI, K. . A new pentanorlanostane derivative, cladosporide A, as a characteristic antifungal agent against Aspergillus fumigatus, isolated from Cladosporium sp. Chemical and Pharmaceutical Bulletin , v. 48, p. 1422-1426, 2000.
Hosoe, T ; Fukushima, Kazutaka ; Takizawa, Kayoko ; Miyaji, Makoto ; KAWAI, K. . Three pyrrolyloctatetraenyl-?-pyrones from Auxarthron conjugatum. Phytochemistry , v. 52, p. 459-463, 1999.
Kim, J. A. ; Gusmão, Norma B. ; OKADA, K. ; CAMPOS-TAKAKI, G. M. ; FUKUSHIMA, K. ; NISHIMURA, K. ; Miyaji, Makoto . Identification of Trichophyton tonsurans by random amplified polymorphic DNA. Annales de Dermatologie et de Vénéréologie , v. 11, p. 135-141, 1999.
Kim, J. A. ; TAKIZAWA, K. ; Fukushima, Kasutaka ; NISHIMURA, K. ; MIYAJI, M. . Identification and genetic homogeneity of Trichophyton tonsurans isolated from several regions by random amplified polymorphic DNA. Mycopathologia , v. 145, p. 1-6, 1999.
OKADA, K. ; TAKIZAWA, K. ; MAEBAYASHI, Y. ; NISHIMURA, K. ; MIYAJI, M. ; Fukushima, Kasutaka . Análise do cariotipo de especies de Malbranchea por electroforese em gel de campo pulsado. Revista Symposium , v. 3, p. 38-42, 1999.
HOSOE, T. ; NOZAWA, K. ; LUMLEY, T. C. ; FUKUSHIMA, K. ; TAKIZAWA, K. ; MIYAJI, M. ; KAWAI, K. . Tetranorditerpene lactones, potent antifungal antibiotics for human pathogenic yeasts, from a unique species of Oidiodendron. Chemical and Pharmaceutical Bulletin , v. 47, p. 1591-1597, 1999.
HOSOE, T. ; NOZAWA, K. ; KAWAHARA, N. ; FUKUSHIMA, K. ; NISHIMURA, K. ; MIYAJI, M. ; KAWAI, K. . Isolation of a new potent cytotoxic pigment along with indigotin from the pathogenic basidiomycetous fungus Schizophyllum commune. Mycopathologia , v. 146, p. 9-12, 1999.
OKADA, K. ; PADOVAN, I. ; Fukushima, Kazutaka ; CAMPOS-TAKAKI, G. M. . Extraction and characterization of proteins from cell walls of two strains of Paracoccidioides brasiliensis.. Boletín Micológico , v. 13, p. 117-121, 1998.
Cui, J. ; TANAKA, R. ; TAGUCHI, H. ; SANO, A. ; Ito, E. ; FUKUSHIMA, K. ; TAKEO, K. ; Yoshida, S. ; NISHIMURA, K. ; MIYAJI, M. . Histopathological and electron microscopical studies on experimental Penicillium marneffei infection in mice. Medical Mycology (Oxford) , v. 35, p. 347-353, 1997.
SANO, A. ; NISHIMURA, K. ; HORIE, H. ; FRANCO, M. ; MENDES, R. P. ; COELHO, K. I. R. ; SCAPOLIO, S. H. B. ; Fukushima, Kazutaka ; CAMARGO, Z. P. ; Miyaji, Makoto ; MONTENEGRO, M. R. . Antigenic similarities to Paracoccidioides brasiliensis in thermo-dependent dimorphic fungi isolated from soil in Botucatu, SP, Brazil. Mycopathologia , v. 138, p. 37-41, 1997.
OKADA, K. ; Takizawa, Kayoko ; Maebayashi, Yukio ; Xi, Liyan ; CAMPOS-TAKAKI, G. M. ; Nishimura, Kazuko ; Miyaji, Makoto ; Fukushima, Kazutaka . Ubiquinone systems of the genus Cladosporium and morphologically similar taxa. FEMS Immunology and Medical Microbiology , v. 16, p. 39-43, 1996.
MONTENEGRO, M. R. ; Miyaji, Makoto ; FRANCO, M. ; Nishimura, Kazuko ; COELHO, K. I. R. ; HORIE, H. ; MENDES, R. P. ; SANO, A. ; Fukushima, Kazutaka ; FECCHIO, D. . : Isolation of fungi from nature in the region of Botucatu, State of Sao Paulo, brazil, an endemic area of paracoccidioidomycosis. Memórias do Instituto Oswaldo Cruz (Online) , v. 96, p. 665-670, 1996.
OKADA, K. ; Takizawa, Kayoko ; Maebayashi, Yukio ; Nishimura, Kazuko ; Miyaji, Makoto ; Fukushima, Kazutaka . Ubiquinone system, GC contents and cellular fatty acid composition of species of the form-genusMalbranchea andCoccidioides immitis for chemotaxonomic study. Mycoscience (Tokyo) , v. 36, p. 385-389, 1995.
Takizawa, Kayoko ; OKADA, K. ; Maebayashi, Yukio ; Nishimura, Kazuko ; Miyaji, Makoto ; Fukushima, Kazutaka . Ubiquinone system of the form-genusChrysosporium. Mycoscience (Tokyo) , v. 35, p. 327-330, 1994.
Fukushima, Kazutaka ; Takizawa, Kayoko ; OKADA, K. ; Maebayashi, Yukio ; Nishimura, Kazuko ; Miyaji, Makoto ; Brummer, Paul E. ; Clemons, Karl V. ; Stevens, David A. . Ubiquinone systems of Coccidioides immitis, the causative agent of coccidioidomycosis. FEMS Microbiology Letters , v. 108, p. 243-245, 1993.
Azevedo, E. C. ; Rios, E. M. ; FUKUSHIMA, K. ; CAMPOS-TAKAKI, G. M. . Bacitracin production by a new strain ofBacillus subtilis. Applied Biochemistry and Biotechnology , v. 42, p. 1-7, 1993.
Fukushima, Kazutaka ; TAKIZAWA, K. ; OKADA, K. ; MAEBAYASHI, Y. ; Nishimura, Kazuko ; Miyaji, Makoto . Suitability of sterilization methods for ubiquinone analysis of pathogenic fungi. Transactions of the Mycological Society of Japan , v. 34, p. 473-480, 1993.
Takizawa, K ; Fukushima, Kazutaka ; MAEBAYASHI, Y. ; OKADA, K. ; Nishimura, Kazuko ; MIYAJI, M. . Isolation and structural elucidation of a dihydroubiquinone-9 from the fungus Aureobasidium pullulans. FEMS Microbiology Letters , v. 92, p. 129-132, 1992.
Fukushima, Kazutaka ; NISHIMURA, K. ; Takizawa, Kayoko ; SANO, A. ; CAMPOS-TAKAKI, G. M. ; TATENO, S. ; MIYAJI, M. . Ubiquinone systems of Paracoccidioides brasiliensis and Blastomyces dermatitidis. Nihon Ishinkin Gakkai Zasshi , v. 32, p. 1-4, 1991.
Fukushima, Kazutaka ; Takeo, Kanji ; Takizawa, Kayoko ; Nishimura, Kazuko ; Miyaji, Makoto . Reevaluation of the teleomorph of the genus Histoplasma by ubiquinone systems. Mycopathologia , v. 116, p. 151-154, 1991.
SHIMA, A. ; Fukushima, Kazutaka ; Arai, Tadashi ; TERADA, S. . Dual Inhibitory Effects of the Peptide Antibiotics Leucinostatins on Oxidative Phosphorylation in Mitochondria. Cell Structure and Function , v. 15, p. 53-58, 1990.
Mikami, Yuzuru ; FENG, Y. S. ; Yazawa, Katsukiyo ; Fukushima, Kazutaka ; MAEDA, A. ; UNO, J. ; TERAO, K. ; NAOKI, S. ; AKINORI, K. ; KEN-ICHIRO, S. . A toxic substance produced by Nocardia otitidiscaviarum isolated from cutaneous nocardiosis. Mycopathologia , v. 112, p. 113-118, 1990.
Mikami, Yuzuru ; Yazawa, Katsukiyo ; Fukushima, Kazutaka ; Arai, Tadashi ; Udagawa, Shun-ichi ; Samson, Robert A. . Paecilotoxin production in clinical or terrestrial isolates of Paecilomyces lilacinus strains. Mycopathologia , v. 108, p. 195-199, 1989.
MIKAMI, Y. ; Takashi Yaguchi ; FUKUSHIMA, K. ; YAZAWA, K. ; Arai, Tadashi . A new pigment from Streptomyces lavendulae. Journal of Antibiotics (Tokyo) , v. 40, p. 385-387, 1987.
KURUSU, K. ; OHBA, K. ; Arai, Tadashi ; Fukushima, Kazutaka . New peptide antibiotics LI-F03, 04, 05, 07 and 08, produced by Bacillus polymyxa. I. Isolation and characterization.. Journal of Antibiotics (Tokyo) , v. 40, p. 1506-1514, 1987.
Fukushima, Kazutaka ; Arai, Tadashi ; TERADA, S. . Structure-activity relationships of paecilotoxins (leucinostatins), peptide mycotoxin from Paecilomyces lilacinus.. Journal of Pharmacological Sciences , v. 76, p. 197-1987, 1987.
FUKUSHIMA, K. ; YAZAWA, K. ; Arai, Tadashi . High performance liquid chromatography of saframycins, heterocyclic quinone antitumor antibiotics. Journal of Antibiotics (Tokyo) , v. 39, p. 1602-1604, 1986.
HANO, Y. ; HIRAKURA, K. ; NAMURA, T. ; TERADA, S. ; FUKUSHIMA, K. . . Structures of two new natural Diels-Alder adducts, kuwanons N and D.. Planta Medica (Internet) , v. 2, p. 127-133, 1985.
FUKAI, T. ; HANO, Y. ; HIRAKURA, K. ; NAMURA, T. ; UZAWA, J. ; FUKUSHIMA, K. . Stucture of two natural hypotensive Diels-Alder type adducts, mulberrofurans F and G, from the cultivated mulberry tree (Morus Lhou Koidz). Chemical and Pharmaceutical Bulletin , v. 33, p. 3195-3204, 1985.
YANO, M. ; FUKAI, T. ; NAMURA, T. ; UZAWA, J. ; FUKUSHIMA, K. . Structures of mulberrofuran I, a novel 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus bombycis Koidz). Chemical and Pharmaceutical Bulletin , v. 32, p. 1260-1263, 1984.
FUKAI, T. ; HANO, Y. ; HIRAKURA, K. ; NAMURA, T. ; UZAWA, J. ; FUKUSHIMA, K. . Structures of mulberrofuran J, a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus Lhou (Ser.) ). Heterocycles (Tokyo) , v. 22, p. 1007-1011, 1984.
ARAI, T. ; UNO, J. ; HORIMI, I. ; FUKUSHIMA, K. . Isolation of Neocopiamycin A from Streptomyces hygroscopicus var. crystallogenes, the copiamycin source. Journal of Antibiotics (Tokyo) , v. 37, p. 103-109, 1984.
MIKAMI, Y. ; FUKUSHIMA, K. ; Arai, Tadashi ; SHIBUYA, H. ; OMMURA, Y. . Leucinostatins, peptide mycotoxins produced by Paecilomyces lilacinus and their possible roles in fungal infection. Zentrablatt fur Bacteriologia Microbiologie und Hygiene A , v. 257, p. 275-283, 1984.
FUKAI, T. ; HANO, Y. ; HIRAKURA, K. ; NAMURA, T. ; UZAWA, J. ; FUKUSHIMA, K. . Structures of mulberrofurans F and G, two natural hypotensive Diels-Alder type adducts from the cultivated mulberry tree (Morus Lhou (Ser.) Koidz.). Heterocycles (Tokyo) , v. 22, p. 473-477, 1984.
HIRAKURA, K. ; HANO, Y. ; FUKAI, T. ; NAMURA, T. ; UZAWA, J. ; FUKUSHIMA, K. . Stucture of three new natural Diels-Alder adducts, kuwanon P and X , and mulberrofuran J. from the cultivated mulberry tree (Morus Lhou Koidz). Chemical and Pharmaceutical Bulletin , v. 33, p. 1088-1096, 1984.
Mori, Yuji ; Tsuboi, Makoto ; Suzuki, Makoto ; FUKUSHIMA, K. ; ARAI, T. . Structure of leucinostain B, an uncoupler of mitochondria. Journal of Antibiotics (Tokyo) , v. 36, p. 1084-1086, 1983.
FUKUSHIMA, K. ; ARAI, T. ; Mori, Yuji ; Tsuboi, Makoto ; Suzuki, Motofuni . Studies on peptide antibiotics, leucinostatin. I. Separation, physicochemical properties and biological activities of leucinostatins A and B.. Journal of Antibiotics (Tokyo) , v. 36, p. 1606-1612, 1983.
FUKUSHIMA, K. ; Arai, Tadashi ; Mori, Yuji ; Tsuboi, Makoto ; Suzuki, Makoto . Studies on peptide antibiotics, leucinostatin. II. The structures of leucinostatins A and B. Journal of Antibiotics (Tokyo) , v. 36, p. 1613-1630, 1983.
NAMIKOSHI, M. ; IWASAKI, S. ; SASAKI, K. ; YANO, M. ; FUKUSHIMA, K. ; NOZOE, S. ; OKUDA, S. . Studies on macrocyclic lactone antibiotics. II. Partial structure of azalomycin F4a. Chemical and Pharmaceutical Bulletin , v. 30, p. 1658-1668, 1982.
IWASAKI, S. ; NAMIKOSHI, M. ; SASAKI, K. ; YANO, M. ; FUKUSHIMA, K. ; NOZOE, S. ; OKUDA, S. . Studies on macrocyclic lactone antibiotics. III. Skeletal structure of azalomycin F4a. Chemical and Pharmaceutical Bulletin , v. 30, p. 1669-1673, 1982.
Mori, Yuji ; Tsuboi, Makoto ; Suzuki, Makoto ; Fukushima, Kazutaka ; Arai, Tadashi . Structure of leucinostatin A, new peptide antibiotic from Paecilomyces lilacinus A-267. Journal of the Chemical Society, Chemical Communications , p. 94, 1982.
Mori, Yuji ; Tsuboi, Makoto ; Suzuki, Makoto ; FUKUSHIMA, K. ; ARAI, T. . Isolation of leucinostatin A and one of its constituents, the new amino acid, 4-methyl-6-(2-oxo-butyl)-2-piperidinecarboxylic acid, from Paecilomyces lilacinus A-267. Journal of Antibiotics (Tokyo) , v. 35, p. 543-544, 1982.
IWASAKI, S. ; NAMIKOSHI, M. ; SASAKI, K. ; FUKUSHIMA, K. ; OKUDA, S. . Studies on macrocyclic lactone antibiotics. V. The structures of azalomycins F3a and F5a. Chemical and Pharmaceutical Bulletin , v. 30, p. 4006-4014, 1982.
FUKUSHIMA, K. ; ARAI, T. ; NAMIKOSHI, M. ; OKUDA, S. . Studies on macrocyclic lactone antibiotics. VI. Skeletal structure of copiamycin. Journal of Antibiotics (Tokyo) , v. 35, p. 1480-1492, 1982.
NAMURA, T. ; FUKAI, T. ; MATSUMOTO, J. ; FUKUSHIMA, K. ; MOMOSE, Y. . Structure of mulberrofuran C, a natural hypotensive Diels-Alder adduct from root barks of the cultivated mulberry tree (Morus Bombycis Koidzumi). Heterocycles (Tokyo) , v. 16, p. 759-765, 1981.
NAMURA, T. ; FUKAI, T. ; SATO, E. ; FUKUSHIMA, K. . The formation of moracenin D from kuwanon G.. Heterocycles (Tokyo) , v. 16, p. 983-986, 1981.
NAMIKOSHI, M. ; SASAKI, K. ; KOISO, Y. ; FUKUSHIMA, K. ; IWASAKI, S. ; NOZOE, S. ; OKUDA, S. . Studies on macrocyclic lactone antibiotics. I. Physicochemical properties of azalomycin F4a. Chemical and Pharmaceutical Bulletin , v. 30, p. 1653-1657, 1981.
FUKUSHIMA, K. ; ARAI, T. . Field desorption mass spectrometry of nucleoside antibiotics. Journal of Antibiotics (Tokyo) , v. 31, p. 37-38, 1978.
MAEBAYASHI, Y. ; FUKUSHIMA, K. ; YAMAZAKI, M. . Isolation and structure of red pigment from Aspergillus ochraceus Wilh. Chemical and Pharmaceutical Bulletin , v. 26, p. 1320-1322, 1978.
ARAI, T. ; MIKAMI, Y. ; FUKUSHIMA, K. ; UTSUMI, T. ; YAZAWA, K. . A new antibiotic, leucinostatin, derived from Penicillium lilacinum. Journal of Antibiotics (Tokyo) , v. 26, p. 157-161, 1973.
FUKUSHIMA, K. ; ISHIWATA, K. ; KURODA, S. ; ARAI, T. . Identity of antibiotic P-42-1 elaborated by Actinomyces tumemacerans with kanchanomycin and albofungin. Journal of Antibiotics (Tokyo) , v. 26, p. 65-69, 1973.
F., K. T. ; FUKUSHIMA, K. ; KURODA, S. ; ARAI, T. . Studies on Actinomyces tumemacerans strain INMI P-42 with particular reference to antibiotic production.. Journal of Antibiotics (Tokyo) , v. 24, p. 69-72, 1971.
FUKUSHIMA, K. ; YAZAWA, K. . Biological activity of albonoursin. Journal of Antibiotics (Tokyo) , v. 26, p. 157-161, 1971.
S, N. ; FUKUSHIMA, K. ; S., O. . The isolation of an acyclic C25-isoprenoid alcohol, geranylnerolidol and a new ophiobolin.. Tetrahedron Letters , v. 9, p. 4457-4458, 1968.

Projetos de pesquisa

2008 - 2008

CARACTERIZAÇÃO QUÍMICA, BIOLÓGICA E MOLECULAR DO BIOSSURFACTANTE RUFSAN PRODUZIDO POR CANDIDA LIPOLYTICA SOB CONDIÇÕES OTIMIZADAS, Descrição: Os surfactantes são moléculas anfipáticas constituídas por uma porção hidrofóbica e outra hidrofílica, onde a porção apolar é uma cadeia hidrocarbonada e a polar pode ser iônica (aniônica ou catiônica), não iônica ou anfotérica. Em função da presença dos grupos hidrofílicos e hidrofóbicos, esses compostos tendem a se distribuir nas interfaces, com diferentes graus de polaridade (água-óleo ou ar-água), formando um filme molecular, reduzindo, desse modo, a tensão interfacial e superficial. Dentre as leveduras, representantes do gênero Candida, têm sido utilizados na emulsificação e solubilização de hidrocarbonetos, facilitando o crescimento do microrganismo nestes substratos, através da produção de biossurfactantes. Essas substâncias de origem microbiana têm atraído grande atenção devido às suas características de biodegradabilidade, baixa toxicidade, aceitabilidade ecológica e habilidade de serem produzidas a partir de fontes renováveis e de baixo custo. Estas propriedades dos surfactantes os tornam adequados para várias aplicações industriais, como detergência, emulsificação, lubrificação, capacidade espumante, solubilização e dispersão de fases Portanto, observa-se um aumento da biodisponibilidade de hidrocarbonetos poluentes, através da utilização de agentes surfactantes, que promovem a dessorção e a solubilização de hidrocarbonetos, facilitando assim, a assimilação pelas células microbianas. Portanto, o projeto visa partir das condições otimizadas de biossurfactante produzido por Candida lipolytica, investigar o processo de remoção do óleo diesel em solos contaminados, representando uma considerável contribuição à saúde pública e ao meio ambiente, tendo em vista a persistência e toxicidade dos hidrocarbonetos aromáticos policíclicos derivados do petróleo, em especial, o óleo diesel. . , Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (0) / Especialização: (0) / Mestrado acadêmico: (2) / Mestrado profissional: (0) / Doutorado: (3) . , Integrantes: Kazutaka Fukushima - Coordenador / Galba Maria de Campos-Takaki - Integrante / Kaoru Okada - Integrante / Leonie Asfora Sarubbo - Integrante / Kazuko Fukushima - Integrante.

Histórico profissional

Endereço profissional

Chiba University, Research Center for Pathogenic Fungi and Microbial Toxicoses. , 1-8-1 Inohana, Chuo-ku, 260-8673 - Cbiba, - Japão, Telefone: (43) 2262779, Fax: (43) 2262779

Experiência profissional

2008 - Atual

Universidade Católica de Pernambuco

Vínculo: Professor Visitante, Enquadramento Funcional: Bolsista do CNPq - Professor Visitante, Carga horária: 40

Outras informações:
Atualmente, está na Universidade Católica de Pernambuco como Professor Visitante com bolsa do CNPq, por seis meses, a partir de 01 de julho de 2008 desenvolvendo projeto de pesquisa, participando do Mestrado em Desenvolvimento de Processos Ambientais da UNICAP, como visitante, e ministrando disciplina para o Doutorado da Rede Nordeste de Biotecnologia, Universidade Católica de Pernambuco-RENORBIO.

1967 - 1990

Chiba University

Vínculo: Outro (especifique), Enquadramento Funcional: Professor Assistente

1967 - 1967

Taisho Pharmaceutical Co. Ltd

Vínculo: Outro (especifique), Enquadramento Funcional: Pesquisador