Jirí Plach
Possui graduação em Qualified Engineer pela Institute Of Molecular Genetic(1976) e doutorado em Qualified Agriculture pela Institute Of Molecular Genetic(1985). Atualmente é Pesquisador cientista da Czechoslovak Academy Of Sciences. Tem experiência na área de Medicina Veterinária, com ênfase em Patologia Animal.
Informações coletadas do Lattes em 10/11/2022
Acadêmico
Formação acadêmica
Doutorado em Qualified Agriculture
1980 - 1985
Institute Of Molecular Genetic
Título: Genetic control of resistance to some tumor diseases in the inbred lines of chickens.
Orientador: Jan Svoboda
Idiomas
Inglês
Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.
Alemão
Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.
Áreas de atuação
Grande área: Ciências Agrárias / Área: Medicina Veterinária / Subárea: Patologia Animal/Especialidade: Patologia Aviária.
Produções bibliográficas
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PLACH , Jirí . M. Dual role of CCR2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of CCR2+ T cells. Journal of Immunology (Baltimore) , v. 172, p. 890-898, 2004.
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PLACH , Jirí . J. Close linkage of genes encoding receptors for subgroup A and C of avian sarcoma/leucosis virus on chicken chromosome 28. Animal Genetics , v. 35, p. 176-181, 2004.
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PLACH , Jirí . R. M. Development of a green fluorescent protein metastatic-cancer chick-embryo drug-screen model. Clinical And Experimental Metastasis, v. 21, p. 347-352, 2004.
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PLACH , Jirí . Deletions in the DNA binding domain of the TP53 gene in v- src-transformed chicken cells. In Vitro Cellular & Developmental Biology. Animal , v. 40, p. xxx, 2004.
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PLACH , Jirí . The 3´ untranslated region of the chicken c-src protooncogene modulates gene expression. Folia Biol, Praga, v. 49, p. 51-62, 2003.
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PLACH , Jirí . J. Intraembryonic avian leukosis virus subgroup C (ALV-C) inoculation producing wasting disease in ducks soon after hatching. Folia Biol, Praga, v. 49, p. 100-109, 2003.
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PLACH , Jirí . K. v-src oncogene-specific carboxy-terminal peptide is immunoprotective against Rous sarcoma growth in chickens with MHC class I allele B-F12. Vaccine (Guildford) , v. 21, p. 4694-4699, 2003.
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PLACH , Jirí . The DT40 web site: sampling and connecting the genes of a B cell line. Nucleic Acids Research , v. 30, p. 230-231, 2002.
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PLACH , Jirí . J. Chicken cells - oncogene transformation, immortalization and more. Folia Biol, Praga, v. 48, p. 126-138, 2002.
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PLACH , Jirí . CpG island protects Rous sarcoma virus-derived vectors integrated into nonpermissive cells from DNA methylation and transcriptional suppression. Proc Natl Acad Sci Usa, USA, v. 98, p. 565-569, 2001.
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PLACH , Jirí . D. Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice. Journal of Immunology (Baltimore) , v. 166, p. 4697-47074, 2001.
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PLACH , Jirí . K. DNA vaccination against v-src oncogene-induced tumors in congenic chickens. Vaccine (Guildford) , v. 19, p. 4526-4535, 2001.
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PLACH , Jirí . The chicken - a laboratory animal of the class aves. Folia Biol, v. 46, p. 17-26, 2000.
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PLACH , Jirí . D. Expression of non-specific esterase (NSE) by thyroid folicular epithelium as a marker for the target organ susceptibility to immune system attack. Immunology (Oxford) , v. 201, p. 598-610, 2000.
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PLACH , Jirí . D. Expression of non-specific esterase (NSE) by thyroid folicular Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: A mechanism for cellular human immunodeficiency virus 1 infection. Nature Medicine , v. 6, p. 769-775, 2000.
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PLACH , Jirí . A large database of chicken bursal ESTs as a source for the analysis of vertebrate gene function. Genome Research , v. 10, p. 2062-2069, 2000.
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PLACH , Jirí . Stangassinger, M., Uhlig, K., Schattenkirchner, M., and Schlöndorff, D. Predominance of mononuclear cells expressing the chemokine receptor CCR5 in synovial effusions of patients with different forms of arthritis. Arthr And Rheumatism, v. 42, p. 981-988, 1999.
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PLACH , Jirí . and Svoboda, J. Inhibition of the Rous sarcoma virus long terminal repeat-driven transcription by in vitro methylation: different sensitivity in permissive chicken cells versus mammalian cells. Virology , v. 255, p. 171-181, 1999.
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PLACH , Jirí . Protective effects of type I and type II interferons toward Rous sarcoma virus-induced tumors in chickens. Virology , v. 256, p. 85-91, 1999.
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PLACH , Jirí . A. Analysis of the immune response regulated by MHC in chicken congenic lines. Arch Tierzucht, v. 42, p. 103-105, 1999.
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PLACH , Jirí . Inhibition of the development of spontaneous autoimmune thyroiditis in the obese strain (OS) chickens by in vivo treatment with anti-CD4 or anti-CD8 antibodies. Journal of Autoimmunity , v. 11, p. 119-126, 1998.
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PLACH , Jirí . Genes of chicken MHC regulate the adherence activity of blood monocytes in Rous sarcomas progressing and regressing lines. Veterinary Immunology and Immunopathology , v. 66, p. 143-157, 1998.
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PLACH , Jirí . A. Genes of chicken MHC regulate the adherence activity of blood monocytes in Rous sarcomas progressing and regressing lines. . Veterinary Immunology and Immunopathology , v. 66, p. 143-167, 1998.
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PLACH , Jirí . Inbred strains of chickens. Immunology Methods Manual, v. Lefkov, p. 2285-2293, 1997.
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PLACH , Jirí . K. Comparative aspects of the chicken Immunogenetics. Folia Biol, praga, v. 43, p. 133-151, 1997.
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PLACH , Jirí . Three-dimensional organization of actin cytoskeleton and podosomal contact structures in neoplastic cells in vitro. Exp Biol, ON LINE, 1997.
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PLACH , Jirí . J. Specific rejection immunity against src oncogene-induced tumors and involvement of the major histocompatibility complex. Folia Biol, v. 42, p. 42-45, 1996.
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PLACH , Jirí . I., and Svoboda, J. Frequent detection of reviraemia in ducks persistently infected with avian leukosis retroviruses. Folia Biol, Praga, v. 42, p. 247-257, 1996.
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PLACH , Jirí . and Wick, G. Prevention of spontaneous autoimmune thyroiditis in the obese strain (OS) chickens by treatment with monoclonal anti-CD4 antibody. J Vet A, v. 43, p. 211-216, 1996.
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PLACH , Jirí . Influence of the transduced 3´UTR of the c-src oncogene on tumor growth induced by the v-src gene of avian sarcoma virus PR2257. Journal of General Virology , v. 77, p. 1189--1192, 1996.
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PLACH , Jirí . and Dezéléé, P. Phenotypic changes induced by wild type and variant c-src genes carrying C-terminal sequence alterations. Oncogene (Basingstoke) , v. 13, p. 2717-2725, 1996.
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PLACH , Jirí . Vaccination with low oncogenic strain of RSV prevents visceral tumors in chickens. Experimental and Clinical Immunogenetics , v. 12, p. 272-282, 1995.
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PLACH , Jirí . Induction of progression of virus-induced tumors by means of anti-macrophage agents. Immunobiology (Germany) , p. 194-286, 1995.
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PLACH , Jirí . src-specific immunity in inbred chickens bearing v-src DNA- And RSV-induced tumors. Immunogenet 40: 257-265, 1994. 32) Schnegg, G., Dietrich, H., Böeck, G., Plach , J., and Hála, K. The immunohistochemical analysis of cells infiltrating Rous sarcoma virus induced tumors in chickens. Folia Biol, Praga, v. 40, p. 463-475, 1994.
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PLACH , Jirí . K. Genetic analysis of four differing traits (MHC haplotype, tumor response, CD4:CD8 ratio, ev17) in CB and CC congenic chickens. Experimental and Clinical Immunogenetics , v. 10, p. 152-160, 1993.
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PLACH , Jirí . N. Pathogenicity of avian myelocytomatosis virus MC29 in two lines of chickens. Avian Pathology , v. 22, p. 295-310, 1993.
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PLACH , Jirí . Tumor induction by the LTR, v-src, LTR DNA in four B(MHC) congenic lines of chickens. Immunogenet, v. 35, p. 309-315, 1992.
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PLACH , Jirí . and Coudert, F. Molecular genotyping of recombinant congenic lines provides evidence for crossing-over within the B-G region of the major histocompatibility complex of the chicken. Immunogenet, v. 36, p. 270-273, 1992.
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PLACH , Jirí . G. Chicken major histocompatibility complex congenic lines differ in the percentages of lymphocytes bearing CD4 and CD8 antigens. . Animal Genetics , v. 22, p. 279-284, 1991.
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PLACH , Jirí . The influence of bursocytes and thymocytes on graft versus host reaction and IgG level in chickens. Arch Immunol Therap . Experientia , v. 39, p. 199-205, 1991.
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PLACH , Jirí . Graft versus host reaction induced by thymectomized and bursectomized chicken blood. Arch Immunol Therap Exp, v. 39, p. 193-197, 1991.
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PLACH , Jirí . I., and Schulmannová, J. Prague inbred lines of chickens: a biological model for MHC research. Folia Biol, Praga, v. 35, p. 177-196, 1989.
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PLACH , Jirí . and Karakoz, I. B(MHC) antigen dependent modulation of GvH reactivity by neonatal thymectomy And alloimmunization. Folia Biol, Praga, v. 35, p. 121-136, 1989.
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PLACH , Jirí . The B-G region genes of the chicken MHC are responsible for lethal graft-vs.-host disease in newly hatched chickens. Folia Biol, v. 34, p. 84-98, 1988.
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PLACH , Jirí . An analysis of the response of recombinant congenic lines of chickens to RSV challenge provides evidence for further complexity of the genetic structure of chicken MHC(B). Folia Biol, Praga, v. 34, p. 170-181, 1988.
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PLACH , Jirí . M. Mouse sera contain natural antibodies directed exclusively against polymorphic non-histocompatibility antigens of the chicken Ea-A blood group system. Folia Biol, v. 32, p. 116-127, 1986.
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PLACH , Jirí . Concomitant immunity leads to retardation or acceleration of the growth of Rous sarcomas in genetically resistant or susceptible inbred lines of chickens. Folia Biol, Praga, v. 32, p. 334-348, 1986.
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PLACH , Jirí . Age-dependent complementation of the B(MHC) alleles and a non-B allele controling resistance to progression of Rous sarcomas, and genetic independence of resistance to induction of tumors in the model of inbred lines of chickens. Folia Biol, Praga, v. 31, p. 284-296, 1985.
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PLACH , Jirí . E. Effect of the expression of an endogenous viral gene on the growth of tumors induced by Rous sarcoma virus in chickens. Folia Biol, Praga, v. 31, p. 235-240, 1985.
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PLACH , Jirí . E. Genetic linkage of endogenous viral loci with the B(MHC) and C histocompatibility loci in chickens. Folia Biol, Praga, v. 31, p. 353-356, 1985.
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PLACH , Jirí . I., and patenková, Z. Different importance of primary lymphoid organs for Rous sarcoma regression in inbred lines of chickens. Folia Biol, v. 30, p. 177-188, 1984.
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PLACH , Jirí . M. Syngeneic lines of chickens. VII. The lines derived from the recombinants at the B complex (MHC) of Rous sarcoma regressor and progressor inbred lines of chickens. Folia Biol, Praga, v. 30, p. 189-201, 1984.
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PLACH , Jirí . , V. Resistance to Marek´s disease is controlled by a gene within the B-F region of the chicken major histocompatibility complex in Rous sarcoma regressor or progressor inbred lines of chickens. Folia Biol, v. 30, p. 251-258, 1984.
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PLACH , Jirí . Hierarchy of the B(MHC) haplotypes controlling resistance to Rous sarcomas in a model of inbred lines of chickens. Folia Biol, Praga, v. 30, p. 412-425, 1984.
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PLACH , Jirí . Failure to confirm the role of immunological tolerance to B(MHC) alloantigens in the growth of RSV-induced tumors in chickens. Folia Biol, Praga, v. 28, p. 283-288, 1982.
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PLACH , Jirí . Vilhelmová, M., and patenková, Z. Interstrain differences in the reactivity of normal mouse sera against erythrocyte surface antigens of inbred chicken lines. Folia Biol, v. 28, p. 344-356, 1982.
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PLACH , Jirí . New recombinant allele in the B-complex of the chicken. Folia Biology, v. 25, p. 323-324, 1981.
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PLACH , Jirí . J. Role of the B-G region antigen in the humoral immune response to the B-F - region antigen of chicken MHC. Immunogenet, v. 14, p. 393-401, 1981.
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PLACH , Jirí . V. Genetic control of Rous sarcoma regression in inbred lines of chickens. Folia Biol, Praga, v. 27, p. 289-300, 1981.
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PLACH , Jirí . V. Location of the gene responsible for Rous sarcoma regression in the B-F region of the B complex (MHC) of the chicken. Folia Biol, Praga, v. 27, p. 363-368, 1981.
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PLACH , Jirí . and Derka, J. Differences in red cell shape of two inbred chicken lines. Theoretical and Applied Genetics , v. 55, p. 113-117, 1979.
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PLACH , Jirí . M. A spontaneous chicken chimaera with serologically and morphologically different types of erathrocytes. Folia Biology, Praga, v. 25, p. 389-321, 1979.
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PLACH , Jirí . V. Regression of tumors induced by Rous sarcoma virus in different inbred lines of chickens. Folia Biol, v. 25, p. 335-336, 1979.
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PLACH , Jirí . K. Genetics of the immune system. In: Poultry Genetics, Breeding and Technology. In: W. M., and Aggrey. (Org.). CAB International. : , 2003, v. , p. 293-309.
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PLACH , Jirí . J. Major histocompatibility complex (MHC) antigens. In. In: Griebel, P., Bazin, H., Govaerts. (Org.). Handbook of Vertebrate Immunology. : eds. Pastoret, 1998, v. , p. 92-95.
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PLACH , Jirí . Major histocompatibility complex (MHC) antigens. In. In: Griebel, P., Bazin, H., Govaerts. (Org.). Handbook of Vertebrate Immunology. : eds. Pastoret, 1998, v. , p. 92-95.
Histórico profissional
Endereço profissional
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Czechoslovak Academy Of Sciences. , Flemingovo n. 2, 141 00 - Prague, - República Tcheca, URL da Homepage:
Experiência profissional
1989 - Atual
Czechoslovak Academy Of SciencesVínculo: Celetista, Enquadramento Funcional: Pesquisador cientista, Carga horária: 44, Regime: Dedicação exclusiva.
Atividades
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01/1989
Pesquisa e desenvolvimento , Genéticas Moleculares, .,Linhas de pesquisa
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