David A Campbell
Possui graduação em Microbiology pela Reading University(1976) e doutorado em Microbiology pela University England(1979). Atualmente é professor titular da University Of California At Los Angeles.
Informações coletadas do Lattes em 10/11/2022
Acadêmico
Formação acadêmica
Doutorado em Microbiology
1976 - 1979
University England
Título: Recombinant human influenza viruses: genetics of virulence.
Orientador: Prof Harry Smith and Dr. Clive Sweet.
Idiomas
Inglês
Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.
Francês
Compreende Bem, Fala Bem, Lê Bem, Escreve Razoavelmente.
Participação em eventos
2nd Buriti Workshop -- Transfection of Parasites, Brasilia.2nd Buriti Workshop - Transfection of Parasites, Brasilia. 1995. (Outra).
1st Buriti Workshop -- Molecular Biology of Parasites, Brasilia.1st Buriti Workshop - Molecular Biology of Parasites, Brasilia. 1994. (Outra).
Session Chairman, Molecular Parasitology Meeting XIV.Session Chairman, Molecular Parasitology Meeting XIV. 1993. (Outra).
Organizer, 3rd West Coast Kinetoplastid Workshop.Organizer, 3rd West Coast Kinetoplastid Workshop. 1993. (Outra).
Workshop at CIDEIM, Cali - PCR Detection of American Trypanosomes.Workshop at CIDEIM, Cali - PCR Detection of American Trypanosomes. 1992. (Outra).
Session Chairman, 1st West Coast Kinetoplastid Workshop, Asilomar.Session Chairman, 1st West Coast Kinetoplastid Workshop, Asilomar. 1988. (Outra).
Produções bibliográficas
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CAMPBELL, David A . The Trypanosoma brucei La protein is a candidate poly(U) shield that impacts spliced leader RNA maturation and tRNA intron removal.. Int J Parasitol, v. 1;35(4, p. 359-366, 2005.
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CAMPBELL, David A . Trypanosomatid biodiversity in Costa Rica: genotyping of parasites from Heteroptera using the Spliced leader RNA gene. Parasitology (London) , v. x:x-x., 2004.
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CAMPBELL, David A . Diversity of insect trypanosomatids assessed from the spliced leader RNA and 5S rRNA genes and intergenic regions. The Journal of Eukaryotic Microbiology , v. x: x-x, 2004.
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CAMPBELL, David A . SmD1 is required for spliced leader RNA biogenesis. Eukaryotic Cell, v. 3, p. 241-244, 2004.
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CAMPBELL, David A . HygR and PurR plasmid vectors for episomal transfection of Trypanosoma cruzi. Memórias do Instituto Oswaldo Cruz , v. 99(5):, p. 513-516, 2004.
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CAMPBELL, David A . 3'-End polishing of the kinetoplastid spliced leader RNA is performed by SNIP, a 3'->5'exonuclease with a Motley assortment of small RNA substrates. Mol Cell Biol, v. 24(23), p. 10390-10396, 2004.
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CAMPBELL, David A . The determinants of Chagas disease: connecting parasite and host genetics. Curr Mol Med, v. 4(6), p. 549-562, 2004.
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CAMPBELL, David A . Diversity of insect trypanosomatids assessed from the spliced leader RNA and 5S rRNA genes and intergenic regions. J Eukaryot Microbiol, v. 51(3):, p. 283-290, 2004.
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CAMPBELL, David A . The 3'termini of small RNAs in Trypanosoma brucei. FEMS Microbiology Letters , v. 236(1), p. 73-78, 2004.
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CAMPBELL, David A . SmD1 is required for spliced leader RNA biogenesis.. Eukaryot Cell, v. 3(1), p. 241-244, 2004.
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CAMPBELL, David A . Transcription in kinetoplastid protozoa: why be normal? . Eukaryot Cell, v. 236(1), p. 273-278, 2004.
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CAMPBELL, David A . The Leishmania tarentolae spliced leader contains determinants for association with polysomes. The Journal Of Biological Chemistry, v. 278, p. 38269-38275, 2003.
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CAMPBELL, David A . A new species of trypanosomes isolated from South American bats, Trypanosoma desterris sp. n. Parasitology (London) , v. 127, p. 265-271, 2003.
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CAMPBELL, David A . Exportin 1 mediates nuclear export of the kinetoplastid Spliced Leader RNA. Eukaryotic Cell, v. 2, p. 222-230, 2003.
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CAMPBELL, David A . Evidence for multiple hybrid groups in Trypanosoma cruzi. International Journal for Parasitology , v. 33, p. 269-279, 2003.
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CAMPBELL, David A . Genetic diversity of Brazilian Trypanosoma cruzi isolates and phylogenetic positioning of zymodeme 3 based on the internal transcribed spacer of the ribosomal gene. Annals of Tropical Medicine and Parasitology , v. 96, p. 755-764, 2002.
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CAMPBELL, David A . Two distinct functional spliced leader RNA gene arrays in Leishmania tarentolae are found in several lizard Leishmania species. . International Journal for Parasitology , v. 32, p. 1411-1422, 2002.
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CAMPBELL, David A . Nucleoside hydrolase from Leishmania (L.) donovani is an antigen diagnostic for visceral leishmaniasis. Molecular and Biochemical Parasitology , v. 120, p. 315-319, 2002.
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CAMPBELL, David A . Intergenic and external transcribed spacers of ribosomal RNA genes in lizard-infecting Leishmania: Molecular structure and phylogenetic relationship to mammal-infecting Leishmania in the subgenus Leishmania (Leishmania). Memórias do Instituto Oswaldo Cruz , v. 97, p. 695-701, 2002.
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CAMPBELL, David A . Kinetoplast DNA minicircles of phloem-restricted Phytomonas associated with wilt diseases of coconut and oil palms have a two-domain structure. FEMS Microbiology Letters , v. 205, p. 65-69, 2001.
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CAMPBELL, David A . Two sequence classes of kinetoplastid 5S ribosomal RNA gene revealed among Bodonid spliced leader RNA gene arrays.. FEMS Microbiology Letters , v. 204, p. 233-237, 2001.
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CAMPBELL, David A . Diplonema spp. possess spliced leader RNA genes similar to the Kinetoplastida.. The Journal of Eukaryotic Microbiology , v. 48, p. 325-331, 2001.
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CAMPBELL, David A . The spliced leader RNA gene array in phloem-restricted plant trypanosomatids (Phytomonas) partitions into two major groupings: epidemiological implications. Parasitology (London) , v. 122, p. 289-297, 2001.
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CAMPBELL, David A . A mini-exon multiplex polymerase chain reaction to distinguish the major groups of Trypanosoma cruzi and T. rangeli in the Brazilian Amazon. Transactions of the Royal Society of Tropical Medicine and Hygiene , v. 95, p. 97-99, 2001.
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CAMPBELL, David A . In vitro transcription of mutated Leishmania tarentolae spliced leader RNA genes approximates in vivo patterns. Molecular and Biochemical . Parasitology (London) , v. 111, p. 391-399, 2000.
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CAMPBELL, David A . 5S ribosomal RNA gene sequences define at least eight groups of plant trypanosomatids (Phytomonas spp.): phloem-restricted pathogens form a distinct section. The Journal of Eukaryotic Microbiology , v. 47, p. 569-574, 2000.
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CAMPBELL, David A . Intraspecific heterogeneity in the mini-exon gene localization of Leishmania (Viannia) panamensis and Leishmania (Viannia) guyanensis from Colombia. The Journal of Parasitology , v. 86, p. 1250-1253, 2000.
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CAMPBELL, David A . Characterization of Leishmania sp. strains isolated from autochthonous cases of human cutaneous leishmaniasis in Santa Catarina State, southern Brazil. Acta Tropica , v. 74, p. 89-93, 2000.
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CAMPBELL, David A . Populational heterogeneity of Brazilian Trypanosoma cruzi isolates revealed by the mini-exon and ribosomal spacers. Memórias do Instituto Oswaldo Cruz , v. 94, p. 195-197, 1999.
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CAMPBELL, David A . The role of intron structures in trans-splicing and cap 4 formation for the Leishmania Spliced Leader RNA. The Journal Of Biological Chemistry, v. 274, p. 19361-19367, 1999.
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CAMPBELL, David A . Mini-exon gene sequence polymorphism among Trypanosoma rangeli strains isolated from different geographical regions. Parasitology (London) , v. 118, p. 375-382, 1999.
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CAMPBELL, David A . Transcript termination and 3'-end processing of the Spliced Leader RNA in kinetoplastids. Molecular and Cellular Biology , v. 19, p. 1595-1601, 1999.
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CAMPBELL, David A . The complexity of the sylvatic cycle of Trypanosoma cruzi in Rio de Janeiro state (Brazil) revealed by the non-transcribed spacer of the mini-exon gene. Parasitology (London) , v. 118, p. 161-166, 1999.
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CAMPBELL, David A . Characterization of a GTP-binding protein in the ADP-ribosylation factor subfamily from Leishmania tarentolae. Biochimica and Biophysica Acta, v. 1442, p. 347-352, 1998.
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CAMPBELL, David A . The mini exon gene of Trypanosoma (Nannomonas) simiae: sequence variation between isolates and a distinguishing molecular marker. Acta Tropica , v. 71, p. 199-206, 1998.
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CAMPBELL, David A . Single nucleotide resolution of promoter activity and protein binding for the Leishmania tarentolae Spliced-Leader RNA gene. Molecular and Biochemical Parasitology , v. 94, p. 265-281, 1998.
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CAMPBELL, David A . Efficient trans-splicing of mutated Spliced-Leader exons in Leishmania tarentolae. The Journal Of Biological Chemistry, v. 273, p. 18689-18692, 1998.
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CAMPBELL, David A . Three small nucleolar RNAs identified from the spliced leader-associated RNA locus in the kinetoplastid protozoa. Molecular and Cellular Biology , v. 18, p. 4409-4417, 1998.
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CAMPBELL, David A . The mini-exon gene: A genetic marker for zymodeme III of Trypanosoma cruzi. Molecular and Biochemical Parasitology , v. 95, p. 129-133, 1998.
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CAMPBELL, David A . Brazilian isolates of Trypanosoma cruzi from humans and triatomines classified into two lineages using mini-exon and ribosomal RNA sequences. American Journal of Tropical Medicine and Hygiene , v. 58, p. 807-811, 1998.
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CAMPBELL, David A . Brazilian isolates of Trypanosoma cruzi from humans and triatomines classified into two lineages using mini-exon and ribosomal RNA sequences. American Journal of Tropical Medicine and Hygiene , v. 58, p. 807-811, 1998.
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CAMPBELL, David A . Regulated tRNA import in Leishmania mitochondria. Biochimica et Biophysica Acta , v. 1396, p. 138-142, 1998.
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CAMPBELL, David A . Molecular epidemiology of American Trypanosomiasis in Brazil based on dimorphisms of rRNA and mini-exon gene sequences.. International Journal for Parasitology , v. 28, p. 105-112, 1997.
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CAMPBELL, David A . Mini-exon gene sequences define six groups within the genus Crithidia. The Journal of Eukaryotic Microbiology , v. 44, p. 553-539, 1997.
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CAMPBELL, David A . DNA markers define two major phylogenetic lineages of Trypanosoma cruzi. Molecular and Biochemical Parasitology , v. 83, p. 141-152, 1996.
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CAMPBELL, David A . Human infection by Trypanosoma rangeli in the Brazilian Amazon. Transactions of the Royal Society of Tropical Medicine and Hygiene , v. 90, p. 278-279, 1996.
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CAMPBELL, David A . Detection and identification of human pathogenic Leishmania and Trypanosoma species by hybridization of PCR-amplified mini-exon repeats. Experimental Parasitology , v. 82, p. 242-250, 1996.
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CAMPBELL, David A . The mini-exon genes of three Phytomonas isolates that differ in plant tissue tropism.. FEMS Microbiology Letters , v. 130, p. 177-182, 1995.
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CAMPBELL, David A . Leishmania lainsoni: a peculiar Viannia species. Annals of Tropical Medicine and Parasitology , v. 89, p. 81-82, 1995.
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CAMPBELL, David A . A conserved upstream element is essential for transcription of the Leishmania tarentolae mini-exon gene. The Embo Journal, v. 13, p. 5460-5469, 1994.
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CAMPBELL, David A . Mini-exon gene variation in human pathogenic Leishmania species. Molecular and Biochemical Parasitology , v. 66, p. 261-271, 1994.
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CAMPBELL, David A . Expression of the Leishmania tarentolae ubiquitin-encoding and mini-exon genes. Gene (Amsterdam) , v. 144, p. 45-51, 1994.
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CAMPBELL, David A . The mini-exon gene: A molecular marker for Endotrypanum schaudinni. Parasitology (London) , v. 107, p. 219-224, 1993.
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CAMPBELL, David A . Organization of the mini-exon and 5S rRNA genes in the kinetoplastid Trypanoplasma borreli. Molecular and Biochemical Parasitology . Molecular And Biochemical Parasitolog, v. 61, p. 127-136, 1993.
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CAMPBELL, David A . Transcriptional linkage of the genes for calmodulin, EF-Hand 5 protein and ubiquitin-EP52 in Trypanosoma brucei. Molecular and Cellular Biology , v. 13, p. 206-216, 1993.
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CAMPBELL, David A . Allelic polymorphism of the Trypanosoma brucei polyubiquitin gene. Molecular and Biochemical Parasitology , v. 55, p. 187-196, 1992.
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CAMPBELL, David A . Identification of a gp63 surface glycoprotein in Leishmania tarentolae. FEMS Microbiology Letters , v. 86, p. 89-92, 1992.
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CAMPBELL, David A . PCR amplification of mini-exon genes differentiates Trypanosoma cruzi from Trypanosoma rangeli. Molecular And Cellular Probes, v. 6, p. 237-243, 1992.
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CAMPBELL, David A . Identification of a new EF-Hand superfamily member from Trypanosoma brucei. Molecular and General Genetics , v. 233, p. 225-230, 1992.
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CAMPBELL, David A . Bodo caudatus medRNA and 5S genes: Tandem arrangement and phylogenetic analysis. Biochemical and Biophysical Research Communications , v. 182, p. 1053-1059, 1992.
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CAMPBELL, David A . Ubiquitin-EP52 fusion protein homologs from Trypanosoma brucei. Nucleic Acids Research , v. 18, p. 7181., 1990.
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CAMPBELL, David A . Tandemly linked tRNAGln, tRNAVal and tRNALys genes in Trypanosoma brucei.. Nucleic Acids Research , v. 22, p. 9479, 1989.
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CAMPBELL, David A . Identification of the nuclear genes encoding the leucine- and glycine-specific transfer RNAs of Trypanosoma brucei. Molecular and Biochemical Parasitology , v. 37, p. 257-262, 1989.
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CAMPBELL, David A . Internal frameshifts within COII and MURF3 mitochondrial genes of Leishmania tarentolae are corrected by RNA editing: Evidence for translation of the edited COII mRNA. Proceedings Of The National Academy Of Sciences U S A, v. 86, p. 6220-6226, 1989.
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CAMPBELL, David A . A polyubiquitin gene from Trypanosoma brucei. Molecular and Biochemical Parasitology , v. 37, p. 147-150, 1989.
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CAMPBELL, David A . Kinetoplastid mitochondria contain functional tRNAs which are encoded in nuclear DNA and also contain small minicircle and maxicircle transcripts of unknown function. Nucleic Acids Research , v. 17, p. 5427-5446, 1989.
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CAMPBELL, David A . c2X75, A derivative of the cosmid vector c2XB. Nucleic Acids Research , v. 17, p. 458, 1989.
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CAMPBELL, David A . Sequence of a cDNA clone for the ND1 gene from Leishmania major: potential uridine addition in the polyadenosine tail. Molecular and Biochemical Parasitology , v. 36, p. 197-200, 1989.
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CAMPBELL, David A . Nucleotide sequence of rat liver iodothyronine 5'-monodeiodinase (5'-MD): its identity with protein disulfide isomerase. Biochemical and Biophysical Research Communications , v. 155, p. 1297-1304, 1988.
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CAMPBELL, David A . Enzyme binding-inhibiting assay for iodothyronine 5'-monodeiodinase (5'-MD) and its application to isolation of complementary deoxyribonucleic acid clones for the 5'-MD in rat liver. Endocrinology (Philadelphia) , v. 1232, p. 1264-1272, 1988.
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CAMPBELL, David A . An unusually compact ribosomal DNA repeat in the protozoan Giardia lamblia. Nucleic Acids Research , v. 15, p. 4065-4084, 1987.
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CAMPBELL, David A . Precise identification of cleavage sites involved in the unusual processing of trypanosome ribosomal RNA. Journal of Molecular Biology , v. 196, p. 113-124, 1987.
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CAMPBELL, David A . Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes. Nature (London) , v. 311, p. 350-355, 1984.
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CAMPBELL, David A . The 5'-limit of transposition and upstream barren region of a trypanosome VSG gene: Tandem 76-base-pair repeats flanking (TAA)90. Nucleic Acids Research , v. 12, p. 2744-2759, 1984.
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CAMPBELL, David A . The use of ultrathin cryosections for localisation of influenza virus antigens in infected Vero cell cultures. Histochemistry, v. 80, p. 497-501, 1984.
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CAMPBELL, David A . Genetic composition and virulence of influenza virus: Differences in facets of virulence in ferrets between two pairs of recombinants with RNA segments of the same parental origin. Journal of General Virology , v. 58, p. 387-398, 1982.
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CAMPBELL, David A . Comparisons of virulence of influenza virus recombinants in ferrets in relation to their behaviour in man and their genetic constitution. Journal of General Virology , v. 44, p. 37-44, 1979.
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CAMPBELL, David A . Trypanosoma cruzi: Cepas de Eleição. In: Doença de Chagas. Manual para experimentação animal. Rio de Janeiro: Editora FIOCRUZ, 2000.
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CAMPBELL, David A . The determinants of Chagas disease: connecting parasite and host genetics. In: UCLA. (Org.). Current Molecular Medicine. Loa Angeles: , 2003, v. xx:x-x, p. -.
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CAMPBELL, David A . Transcription in the kinetoplastid protozoa: why be normal? . In: UCLA. (Org.). Microbes and Infection. Los Angeles: , 2003, v. 5, p. 1231-1240.
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CAMPBELL, David A . Transcription of the kinetoplastid Spliced Leader RNA gene. In: UCLA. (Org.). Parasitology Today. Los Angeles: , 2000, v. 16, p. 78-82.
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CAMPBELL, David A . Characterization of Trypanosoma rangeli strains isolated in Central and South America: An overview.. In: Editora FIOCRUZ. (Org.). Memórias do Instituto Oswaldo Cruz. Rio de Janeiro: , 1999, v. 94, p. 203-209.
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CAMPBELL, David A . Use of molecular probes and PCR for detection and typing of Leishmania - a mini-review. In: EDITORA FIOCRUZ. (Org.). Memórias do Instituto Oswaldo Cruz. Ruo de Janeiro: , 1994, v. 89, p. 463-469.
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CAMPBELL, David A . Resumen del taller sobre el uso de la reaccion en cadena de la polimerasa (PCR) para distinguir entre Trypanosoma cruzi y Trypanosoma rangeli. In: UCLA. (Org.). Biomedica. : , 1993, v. 13, p. 94-100.
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CAMPBELL, David A . Expression of surface antigen genes in Trypanosoma brucei involves a novel system of discontinuous transcription. In: Vaccines, 1985. Molecular and Chemical Basis of Resistance to Parasitic, Bacterial Viral Diseases. In: Cold Spring Harbor Press, New York. (Org.). Cold Spring Harbor Press. New York: , 1985, v. , p. 61-66.
Outras produções
CAMPBELL, David A . Vaccines for Equine Influenza. 1984.
Prêmios
2004
Editorial Board, Eukaryotic Cell.
2002
ad hoc Reviewer 2002/2004, TMP Study Section, NIH (6/02, 5/03, 2/04).
2002
Editorial Board, Brazilian Journal of Pathology.
2001
Visiting Scientist, CIRAD, Montpellier, France.
1999
Board of Reviewers 1999/2005, Journal of Eukaryotic Microbiology.
1996
President 1996/1998, Southern California Society of Parasitologists.
1995
Visiting Professor, University of Brasilia UnB , Brazil.
1992
Visiting Scientist, CIDEIM, Cali, Colombia.
1992
Burroughs-Wellcome New Investigator 1990/1992, Burroughs-Wellcome New Investigator in Molecular Parasitology..
Histórico profissional
Endereço profissional
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University of California, University of California, Los Angeles, Department Of Microbiology Immunology Molecular Genetics. , 825 Molecular Sciences Building- 609 Charles E. Young Drive East, CA 90095-1489 - Los Angeles, - Estados Unidos, URL da Homepage:
Experiência profissional
1979 - Atual
University Of California At Los AngelesVínculo: Servidor Público, Enquadramento Funcional: Professor titular, Carga horária: 40
Atividades
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03/1979
Pesquisa e desenvolvimento , David Geffen School Of Medicine At Ucla, Department Of Microbiology Immunology Molecular Genetics.,Linhas de pesquisa
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