Katsuhiro Konno

Possui mestrado em Deaprtment of Chemistry - Hokkaido University (1977) e doutorado em Department of Chemsitry - Hokkaido University (1986). Atualmente é associate professor - University of Toyama. Tem experiência na área de Química, com ênfase em Química dos Produtos Naturais, atuando principalmente nos seguintes temas: synthesis, biological activity, solitary wasp venom, clitocybe acromelalga e 1a25-dihydroxyvitamin d3.

Informações coletadas do Lattes em 10/11/2022

Acadêmico

Formação acadêmica

Doutorado em Department of Chemsitry

1977 - 1986

Hokkaido University
Título: Toxic principles of poisonous mushroom Clitocybe acromelalga
Orientador: Professor Doutor Takeshi Matsumoto
Palavras-chave: poisonous mushroom; toxic principle; isolation and structure; synthesis; acromelic acid; glutamate agonist. Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica / Especialidade: Química dos Produtos Naturais. Grande Área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica / Especialidade: Estrutura, Conformação e Estereoquímica. Grande Área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica / Especialidade: Síntese Orgânica. Setores de atividade: Fabricação de Produtos Farmacêuticos; Fabricação de Produtos Químicos.

Mestrado em Deaprtment of Chemistry

1975 - 1977

Hokkaido University
Orientador: Professor Doutor Takeshi Matsumoto
Palavras-chave: isolation and structure; toxic principle; mushroom toxins; Clitocybe acromelalga.Grande área: Ciências Exatas e da Terra / Área: Química. Grande Área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica. Grande Área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica / Especialidade: Química dos Produtos Naturais. Setores de atividade: Fabricação de Produtos Químicos; Fabricação de Produtos Farmacêuticos.

Pós-doutorado

1986 - 1989

Pós-Doutorado. , Columbia University. , Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica / Especialidade: Química dos Produtos Naturais.

Idiomas

Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Espanhol

Compreende Pouco, Fala Pouco, Lê Pouco, Escreve Pouco.

Português

Compreende Razoavelmente, Fala Razoavelmente, Lê Razoavelmente, Escreve Pouco.

Japonês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Áreas de atuação

Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica/Especialidade: Química dos Produtos Naturais.

Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica/Especialidade: Evolução, Sistemática e Ecologia Química.

Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica/Especialidade: Síntese Orgânica.

Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Química de Macromoléculas/Especialidade: Proteínas.

Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica/Especialidade: Estrutura, Conformação e Estereoquímica.

Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Química de Macromoléculas.

Produções bibliográficas

Sant?Anna, Célia L. ; Carvalho, Luciana R. ; Fiore, Marli F. ; Silva-Stenico, Maria Estela ; Lorenzi, Adriana S. ; Rios, Fernanda R. ; Konno, Katsuhiro ; Garcia, Carlos ; Lagos, Nestor . Highly Toxic Microcystis aeruginosa Strain, Isolated from São Paulo Brazil, Produce Hepatotoxins and Paralytic Shellfish Poison Neurotoxins. Neurotoxicity Research , v. 19, p. 389-402, 2011.
Alvarez-Flores, M. P. ; Furlin, D. ; Ramos, O. H. P. ; Balan, A. ; KONNO, K. ; CHUDZINSKI-TAVASSI, A. M. . Losac, the First Hemolin that Exhibits Procogulant Activity through Selective Factor X Proteolytic Activation. The Journal of Biological Chemistry (Print) , v. 286, p. 6918-6928, 2011.
Zaharenko, Andre? J. ; Picolo, Gisele ; Ferreira, Wilson A. ; Murakami, Takanori ; Kazuma, Kohei ; Hashimoto, Masaru ; Cury, Yara ; de Freitas, Jose? C. ; Satake, Motoyoshi ; Konno, Katsuhiro . Bunodosine 391: An Analgesic Acylamino Acid from the Venom of the Sea Anemone. Journal of Natural Products (Print) , v. 74, p. 378-382, 2011.
Picolo, Gisele ; Hisada, Miki ; Moura, Analuê B. ; Machado, Maurício F.M. ; Sciani, Juliana M. ; Conceição, Isaltino M. ; Melo, Robson L. ; Oliveira, Vitor ; Lima-Landman, Maria Teresa R. ; Cury, Yara ; KONNO, K. ; HAYASHI, M. A. F. . Bradykinin-related peptides in the venom of the solitary wasp Cyphononyx fulvognathus. Biochemical Pharmacology , v. 79, p. 478-486, 2010.
Schiavon, Emanuele ; Stevens, Marijke ; Zaharenko, André J. ; KONNO, K. ; Tytgat, Jan ; Wanke, Enzo . Voltage-gated sodium channel isoform-specific effects of pompilidotoxins. The FEBS Journal (Print) , v. 277, p. 918-930, 2010.
Nakayama, Hitoshi ; Yokote, Sawana ; Setoguchi, Ritsuko ; Shimizu, Eisuke ; Kawahara, Kohichi ; Kuniyasu, Akihiko ; Shirasaki, Tetsuya ; Takahama, Kazuo ; Kawai, Nobufumi ; Yamaoka, Kaoru ; Kinoshita, Eiji ; KONNO, K. . A Synthetic Approach to Develop Peptide Inhibitors Selective for Brain-Type Sodium Channels on the Basis of Pompilidotoxin Structure. Heterocycles (Sendai) , v. 79, p. 925-933, 2009.
Sousa, Juliana C. ; Berto, Raquel F. ; Gois, Elicélia A. ; Fontenele-Cardi, Nauíla C. ; Honório-Júnior, José E.R. ; Konno, Katsuhiro ; Richardson, Michael ; Rocha, Marcos F.G. ; Camargo, Antônio A.C.M. ; Pimenta, Daniel C. ; KONNO, K. . Leptoglycin: A new Glycine/Leucine-rich antimicrobial peptide isolated from the skin secretion of the South American frog Leptodactylus pentadactylus (Leptodactylidae). Toxicon (Oxford) , v. 54, p. 23-32, 2009.
SILVA, C ; KONNO, K. . Tissue distribution in mice of BPP 10c, a potent proline-rich anti-hypertensive peptide of Bothrops jararaca?. Toxicon (Oxford) , v. 51, p. 515-523, 2008.
Arcisio-Miranda, Manoel ; dos Santos Cabrera, Marcia Perez ; Konno, Katsuhiro ; Rangel, Marisa ; Procopio, Joaquim ; KONNO, K. . Effects of the cationic antimicrobial peptide eumenitin from the venom of solitary wasp Eumenes rubronotatus in planar lipid bilayers: Surface charge and pore formation activity?. Toxicon (Oxford) , v. 51, p. 736-745, 2008.
Rioli, Vanessa ; Prezoto, Benedito C. ; Konno, Katsuhiro ; Melo, Robson L. ; Klitzke, Clécio F. ; Ferro, Emer S. ; Ferreira-Lopes, Mônica ; Camargo, Antonio C. M. ; Portaro, Fernanda C. V. ; KONNO, K. . A novel bradykinin potentiating peptide isolated from Bothrops jararacussu venom using catallytically inactive oligopeptidase EP24.15. The FEBS Journal (Print) , v. 275, p. 2442-2454, 2008.
MPS, C. ; ARCISIO-MIRANDA, M. ; COSTA, S. T. B. ; KONNO, K. ; RUGGIEROB, J. R. ; RUGGIERO NETO, J. ; PROCOPIO, J. . Study of the mechanism of action of Anoplin, a helical antimicrobial decapeptide with ion channel-like activity, and the role of the amidated C-terminus. Journal of Peptide Science , v. 14, p. 661-669, 2008.
ZAHARENKO, A ; FERREIRAJR, W ; DEOLIVEIRA, J ; KONNO, K ; RICHARDSON, M ; SCHIAVON, E ; WANKE, E ; DEFREITAS, J ; KONNO, K. . Revisiting cangitoxin, a sea anemone peptide: Purification and characterization of cangitoxins II and III from the venom of Bunodosoma cangicum?. Toxicon (Oxford) , v. 51, p. 1303-1307, 2008.
Konno, Katsuhiro ; Picolo, Gisele ; Gutierrez, Vanessa P. ; Brigatte, Patrícia ; Zambelli, Vanessa O. ; Camargo, Antonio C.M. ; Cury, Yara ; KONNO, K. . Crotalphine, a novel potent analgesic peptide from the venom of the South American rattlesnake Crotalus durissus terrificus. Peptides (New York, N.Y. 1980) , v. 29, p. 1293-1304, 2008.
ZAHARENKO, A ; FERREIRAJR, W ; OLIVEIRA, J ; RICHARDSON, M ; PIMENTA, D ; KONNO, K ; PORTARO, F ; DEFREITAS, J ; KONNO, K. . Proteomics of the neurotoxic fraction from the sea anemone Bunodosoma cangicum venom: Novel peptides belonging to new classes of toxins. Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics , v. 3, p. 219-225, 2008.
SILVA, C ; IANZER, D ; PORTARO, F ; KONNO, K ; FARIA, M ; FERNANDES, B ; CAMARGO, A ; KONNO, K. . Characterization of urinary metabolites from four synthetic bradykinin potentiating peptides (BPPs) in mice. Toxicon (Oxford) , v. 52, p. 501-507, 2008.
GUTIERREZ, V ; KONNO, K ; CHACUR, M ; SAMPAIO, S ; PICOLO, G ; BRIGATTE, P ; ZAMBELLI, V ; CURY, Y ; KONNO, K. . Crotalphine induces potent antinociception in neuropathic pain by acting at peripheral opioid receptors. European Journal of Pharmacology , v. 594, p. 84-92, 2008.
CARVALHO, L. R. ; PIPOLE, F. ; WERNER, V. R. ; LAUGHINGHOUSE, H. D. ; CAMARGO, A. C. M. ; RANGEL, M. ; KONNO, K. ; SANTANNA, C. L. . A toxic cynobacterial mixed bloom in an urban coastal lake, Rio Grande do Sul state, southern Brazil. Brazilian Journal of Microbiology (Impresso) , v. 39, p. 761-769, 2008.
PEREIRA, L. S. ; SILVA JR., P. I. ; MIRANDA, M. T. M. ; ALMEIDA, I. C. ; NAOKI, H. ; KONNO, K. ; DAFFRE, S. . Structural and biological characterization of one antibacterial acylpolyamine isolated from the hemocytes of the spider Acanthocurria gomesiana. Biochemical and Biophysical Research Communications , v. 352, p. 953-959, 2007.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; ANTONIAZZI, M. M. ; JARED, C. ; SCIANI, J. M. ; CONCEICAO, I. M. ; CAMARGO, A. C. M. ; PIMENTA, D. C. . Isolation and characterization of a novel bradykinin potentiating peptide (BPP) from the skin secretion of Phyllomedusa hypochondrialis. Peptides (New York) , v. 28, p. 515-523, 2007.
PIMENTA, D. C. ; PREZOTO, I. C. ; KONNO, K. ; MELO, R. L. ; FURTADO, M. F. ; CAMARGO, A. C. M. ; SERRANO, S. . Mass spectrometric analysis of Bothrops jararaca venom peptide fraction. Evidence for sex-based variation among the bradykinin-potentiating peptides,. Rapid Communications in Mass Spectrometry , v. 21, p. 1034-1042, 2007.
MATSUURA, M. ; YAMADA, M. ; SAIKAWA, Y. ; MIYAIRI, K. ; OKUNO, T. ; KONNO, K. ; UENISHI, J. ; HASHIMOTO, K. ; NAKATA, M. . Bolevenine, a toxic protein from the Japanese toadstool Boletus venenatus,. Phytochemistry , v. 68, p. 893-898, 2007.
TAKESHITA, D. ; BENTO, F. M. ; CHAMMAS, R. ; BELIZARIO, J. E. ; CARMONA, A. K. ; MELO, R. L. ; KONNO, K. ; MOLINA, G. ; LISBOA, B. C. G. ; HAN, S. W. . Expression of the selectable marker gene bsrm in BALB/MK cells induces apoptosis. Biochemistry and Cell Biology , v. 85, p. 573-581, 2007.
GOMES, C. L. ; KONNO, K. ; CONCEICAO, I. M. ; IANZER, D. ; YAMANOUYE, N. ; PREZOTO, B. C. ; ASSAKURA, M. T. ; RADIS-BAPTISTA, G. ; YAMANE, T. ; SANTOS, R. A. ; CAMARGO, A. C. M. ; HAYASHI, M. A. F. . Identification of novel bradykinin-potentiating peptides (BPPs) in the venom gland of a rattlesnake allowed the evaluation of the structure-function relationship of BPPs,. Biochemical Pharmacology , v. 74, p. 1350-1360, 2007.
KONNO, K. ; RANGEL, M. ; OLIVEIRA, J. S. ; CABRERA, M. P. ; FONTANA, R. ; HIRATA, I. ; HIDE, I. ; NAKATA, Y. ; MORI, K. ; M. Kawano ; FUCHINO, H. ; SEKITA, S. ; RUGGIERO NETO, J. . Decoralin, a novel linear cationic α-helical peptide from the venom of the solitary eumenine wasp Oreumenes decoratus. Peptides (New York) , v. 28, p. 2320-2327, 2007.
OLIVEIRA, J. S. ; ZAHARENKO, A. J. ; J. C. Freitas ; KONNO, K. ; ANDRADE, S. A. ; PORTARO, F. C. V. ; SANTANNA, O. A. ; TAMBOURGI, D. V. . Caissarolysin I (Bcs I), a new hemolytic toxin from the Brazilian sea anemone Bunodosoma caissarum: Purification and biological characterization. Biochimica et Biophysica Acta. G, General Subjects , v. 1760, p. 453-461, 2006.
TSURUTA, L. R. ; HAYASHI, M. A. F. ; KONNO, K. ; TAMBOURGI, D. V. ; ASSAKURA, M. T. ; CAMARGO, A. C. M. ; SANTANNA, O. A. . A natural carrier effect and the efficient generation of specific antibodies to biologically active peptides. Analytical Biochemistry , v. 353, p. 174-180, 2006.
KONNO, K. ; HISADA, M. ; NAOKI, H. ; ITAGAKI, Y. ; FONTANA, R. ; RANGEL, M. ; OLIVEIRA, J. S. ; CABRERA, M. P. ; RUGGIERO NETO, J. ; YASUHARA, T. . Eumenitin, a novel antimicrobial peptide from the venom of the solitary eumenine wasp Eumenes rubronotatus. Peptides (New York) , v. 27, 2006.
RANGEL, M. ; PRADO, M. P. ; KONNO, K. ; NAOKI, H. ; J. C. Freitas ; MACHADO-SANTELLI, G. M. . Cytoskeleton alterations induced by Geodia corticostylifera depsipeptides in breast cancer cell lines. Peptides, v. 27, 2006.
NIHEI, K. ; M. J. Kato ; YAMANE, T. ; KONNO, K. . An efficient and versatile synthesis of all structural types of acylpolyamine spider toxins. Tetrahedron, 2006.
IANZER, D. ; FERNANDEZ, J. H. ; KONNO, K. ; XAVIER, C. H. ; STOCKLIN, R. ; SANTOS, R. A. S. ; CAMARGO, A. C. M. ; PIMENTA, D. C. . Hemorphin and hemorphin-like peptides isolated from dog pancreas and sheep brain are able to potentiate bradykinin activity in vivo. Peptides, v. 27, 2006.
OLIVEIRA, J. S. ; ZAHARENKO, A. J. ; FERREIRA JR., W. A. ; KONNO, K. ; SHIDA, C. S. ; RICHARDSON, M. ; LUCIO, A. D. ; BEIRAO, P. S. L. ; FREITAS, J. C. . BcIV, a new paralyzing peptide obtained from the venom of the sea anemone Bunodosoma caissarum. A comparison with the Na+ channel toxin BcIII.. Biochimica et Biophysica Acta. G, General Subjects , v. 1764, p. 1592-1600, 2006.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; MARQUES, E. E. ; HIRUMA-LIMA, C. A. ; LIMA, C. ; RICHARDSON, M. ; PIMENTA, D. C. ; LOPES-FERREIRA, M. . Orpotrin: a novel vasoconstrictor peptide from the venom of the Brazilian stingray Potamotrygon gr. Orbignyi. Peptides (New York) , v. 27, p. 3039-3046, 2006.
CONCEICAO, K. ; KONNO, K. ; RICHARDSON, M. ; ANTONIAZZI, M. M. ; JARED, C. ; DAFFRE, S. ; CAMARGO, A. C. M. ; PIMENTA, D. C. . Isolation and biochemical characterization of peptides presenting antimicrobial activity from the skin of Phyllomedusa hypochondrialis.. Peptides (New York) , v. 27, p. 3092-3099, 2006.
TAKAHASHI, E. ; NAKAGAWA, K. ; SUHARA, Y. ; KITTAKA, A. ; NIHEI, K. ; KONNO, K. ; TAKAYAMA, H. ; OZONO, K. ; OKANO, T. . Biological activities of 2α-substituted analogues of 1α,25-dihydroxyvitamin D3 on transcriptional regulation and human promyelocytic leukemia (HL-60) cell proliferation and differentiation. Biological & Pharmaceutical Bulletin , v. 29, p. 2246-2250, 2006.
KONNO, K. ; BRAGA, M. C. V. ; PORTARO, F. C. V. ; J. C. Freitas ; YAMANE, T. ; OLIVERA, B. M. ; PIMENTA, D. C. . Mass spectrometric and high performance liquid chromatography profiling of the venom of the Brazilian vermivorous mollusk Conus regius: feeding behavior and identification of a novel conotoxin. Toxicon , v. 45, p. 113-122, 2005.
KONNO, K. ; PORTARO, F. C. V. ; BASTOS, M. F. ; GUERREIRO, J. R. ; OLIVERA, V. ; CORRAO, S. S. ; TAMBOURGI, D. V. ; SANTANNA, O. A. ; WHITING, P. J. ; CAMARGO, A. C. M. . Inhibition of NUDEL-oligopeptidase activity by the schizophrenia risk factor Disrupted in Schizophrenia 1 (DISC1). PNAS. Proceedings of the National Academy of Sciences of the United States of America , v. 102, p. 3828-3833, 2005.
KONNO, K. ; RICCI-SILVA, M. E. ; FARIA, F. ; RADIS-BAPTISTA, G. ; FONTES, W. ; STOCKLIN, R. ; MICHALET, S. ; YAMANE, T. ; CHUDZINSKI-TAVASSI, A. M. . Protein mapping of the salivary complex from a hematophaghous leech. OMICS- A Journal of Itergratove Biology, v. 9, p. 194-208, 2005.
KONNO, K. ; MIURA, D. ; A. W. Norman ; MIZWICKI, M. T. ; FUJISHIMA, T. ; KITTAKA, A. ; TAKAYAMA, H. ; ISHIZUKA, S. . The antagonism between 2-methyl-1,25-dihydroxyvitamin D3 and 2-methyl-20-epi-1,25-dihydroxyvitamin D3 in non-genomic pathway-mediated biological responses induced by 1α,25-dihydroxyvitamin D3 assessed by NB4 cell differentiation. Journal of Steroid Biochemistry and Molecular Biology , v. 94, p. 469-479, 2005.
KONNO, K. ; PALMA, M. S. ; NIHEI, K. ; SALAMONI, S. D. ; COSTA, J. C. ; TAVARES, A. A. ; ABREU, D. S. ; VENTURIN, G. T. ; CUNHA, F. B. ; OLIVEIRA, R. M. . Antiepileptic effect of acylpolyaminetoxin JSTX-3 on rat hippocampal CA1 neurons in vitro. Brain Research , v. 1048, p. 170-176, 2005.
KONNO, K. ; RANGEL, M. ; BRUNALDI, K. ; PROCOPIO, J. ; J. C. Freitas . Neurotoxic activity induced by a haemolytic substance in the extract of the marine sponge Geodia corticostylifera. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology , v. 141, p. 207-215, 2005.
KONNO, K. ; SALAMONI, S. D. ; COSTA, J. C. ; PALMA, M. S. ; NIHEI, K. ; VENTURIN, G. T. ; TAVARES, A. A. ; ABREU, D. S. . The antiepileptic activity of JSTX-3 is mediated by N-methyl-D-aspartate receptors in human hippocampal neurons. NeuroReport (Oxford) , v. 16, p. 1869-1873, 2005.
KONNO, K. ; SOUZA, B. M. ; MENDES, M. A. ; SANTOS, L. D. ; MARQUES, M. R. ; CESAR, L. M. M. ; ALMEIDA, R. N. ; PAGNOCCA, F. C. ; PALMA, M. S. . Structural and functional characterization of two novel peptide toxins isolated from the venom of the social wasp Polybia paulista. Peptides (New York) , v. 26, p. 2157-2164, 2005.
KONNO, K. ; OYAMA, S. ; CANDURI, F. ; LORENZI, C. C. B. ; PERTINEZ, T. A. ; SOUZA, B. M. ; PALMA, M. S. ; RUGGIERO NETO, J. ; AZEVEDO JR, W. F. ; SPISNI, A. . How C-terminal carboxyamidation alters the mast cell degranulating activity of peptides from the venom of the eumenine solitary wasp. Biochemistry (Easton) , v. 43, p. 5608-5617, 2004.
KONNO, K. ; KAWAI, N. . Molecular determinants of two neurotoxins that regulate sodium current inactivation in rat hippocampus. Neuroscience Letters , v. 361, p. 44-46, 2004.
KONNO, K. ; KAWAI, N. . Pompilidotoxins. Novel peptide neurotoxins blocking sodium channel inactivation from solitary wasp venom. Current Medicinal Chemistry - Central Nervous System Agents, v. 4, p. 139-146, 2004.
KONNO, K. ; FONTANA, R. ; MENDES, M. A. ; SOUZA, B. M. ; CESAR, L. M. M. ; MALASPINA, O. ; PALMA, M. S. . Jelleines: a family of antimicrobial peptides from the royal jelly of honey bees (Apis mellifera). Peptides (New York) , v. 25, p. 919-928, 2004.
KONNO, K. ; IANZER, D. ; PIMENTA, D. C. ; MARQUES-PORTO, R. ; PORTARO, F. C. V. ; STOCKLIN, R. ; CAMARGO, A. C. M. . Identification of five new bradykinin potentiating peptides (BPPs) from Bothrops jararaca crude venom by using electrospray ionization tandem mass spectrometry after a two-step liquid chromatography. Peptides (New York) , v. 25, p. 1085-1092, 2004.
KONNO, K. ; OLIVEIRA, J. S. ; ZAHARENKO, A. J. ; PIMENTA, D. C. ; J. C. Freitas ; WANKE, E. . Nav 1.1-1.6 sodium channels binding specificity to sea anemone toxins: unexpected contributions from changes in the IV/ S3-S4 outer loop. The Journal of Biological Chemistry , v. 279, p. 33323-33335, 2004.
KONNO, K. ; CABRERA, M. P. ; SOUZA, B. M. ; FONTANA, R. ; PALMA, M. S. ; AZEVEDO JR, W. F. ; RUGGIERO NETO, J. . Conformation and lytic activity of eumenine mastoparan: a new antimicrobial peptide from wasp venom. Journal of Peptide Research, v. 64, p. 95-103, 2004.
KONNO, K. ; NIHEI, K. ; BERNARDES, L. S. C. ; LOPES, N. P. ; ALBUQUERQUE, S. ; CALVALHO, I. ; RUPO, M. T. ; MARTINS, R. C. C. ; M. J. Kato . Synthesis of trypanocidal tetrahydrofuran lignans. Arckvoc, p. 112-126, 2004.
KONNO, K. ; FUJISHIMA, T. ; LIU, Z. ; TAKAYAMA, H. . Determination of absolute configuration of 1,3-diols by the modified Mosher s method using their di-MTPA esters. Chirality, v. 14, p. 72-80, 2002.
NIHEI, K. ; M. J. Kato ; YAMANE, T. ; PALMA, M. S. ; KONNO, K. . An efficient and versatile synthesis of acylpolyamine spider toxins. Bioorganic & Medicinal Chemistry Letters, v. 12, p. 29-32, 2002.
KONNO, K. ; PALMA, M. S. ; HIRATA, I. ; M. A. Juliano ; L. Juliano ; YASUHARA, T. . Identification of bradykinins in the venoms of solitary scoliid wasps. Toxicon, v. 40, p. 309-312, 2002.
HASHIMOTO, K. ; MATSUMOTO, T. ; NAKAMURA, K. ; OHWADA, S. ; OHUCHI, T. ; HORIKAWA, M. ; KONNO, K. ; SHIRAHAMA, H. . Molecular orbital calculation for the model compounds of kainoid amino acids, agonists of excitatory amino acid receptor. Does the C4-substituent of kainoid directly interact with its receptor?. Bioorg. Med.Chem., v. 10, p. 1373-1379, 2002.
HISADA, M. ; ITAGAKI, Y. ; KONNO, K. ; NAOKI, H. ; NAKAJIMA, T. . Sequencing wasp venom peptides by endopeptidase digestion and nested collision-induced dissociation/post-source decay method. Rapid Commun. Mass Spectr., v. 16, p. 1040-1048, 2002.
D. S. Rao ; M.-L. Siu-Caldera ; P. Vouros ; TAKAYAMA, H. ; KONNO, K. ; FUJISHIMA, T. ; REDDY, G. S. . Metabolism of 2-methyl analogs of 1a,25-dihydroxyvitamin D3 in rat osteosarcoma cells (UMR 106). Biol. Pharmacol. Bull., v. 25, p. 845-852, 2002.
MIYAWAKI, T. ; TSUBOKAWA, H. ; YOKOTA, H. ; K Oguro ; KONNO, K. ; MASUZAWA, T. ; KAWAI, N. . Differential effects of novel wasp toxin on rat hippocampal interneurons. Neurosci. Lett., v. 328, p. 25-28, 2002.
KONNO, K. ; HISADA, M. ; NAOKI, H. ; ITAGAKI, Y. ; YASUHARA, T. ; M. A. Juliano ; L. Juliano ; PALMA, M. S. ; YAMANE, T. . Isolation and sequence determination of peptides in the venom of the spider wasp Cyphononyx dorsalis guided by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry. Toxicon, v. 39, p. 1257-1260, 2001.
DELATORRE, P. ; OLIVIERI, J. R. ; RUGGIERO NETO, J. ; LORENZI, C. C. B. ; CONDURF, F. ; FADEL, V. ; KONNO, K. ; PALMA, M. S. ; YAMANE, T. ; AZEVEDO JR, W. F. . Preliminary cryocrystallography analysis of an eumenine mastoparan toxin isolated from the venom of the wasp Anterhynchium flavomarginatum micado. Biochim. Biophys. Acta, v. 1545, p. 372-376, 2001.
FUJISHIMA, T. ; LIU, Z. ; KONNO, K. ; NAKAGAWA, K. ; OKANO, T. ; YAMAGUCHI, K. ; TAKAYAMA, H. . Highly potent cell differentiating analogues of 1a,25-dihydroxyvitamin D3: Synthesis and biological activity of 2-methyl-1,25-dihydroxyvitamin D3 with side chain modifications. BioMed. Chem., v. 9, p. 525-535, 2001.
NIHEI, K. ; M. J. Kato ; YAMANE, T. ; PALMA, M. S. ; KONNO, K. . 2-Nitro- and 2,4-dinitrobenzenesulfonamides as protective groups for primary amines. Synlett, p. 1167-1169, 2001.
KINOSHITA, E. ; MAEJIMA, H. ; YAMAOKA, K. ; KONNO, K. ; KAWAI, N. ; SHIMIZU, E. ; YOKOTE, S. ; NAKAYAMA, H. ; SEYAMA, I. . Novel wasp toxin discriminates between neuronal and cardiac sodium channels. Molecular Pharmacology, v. 59, p. 1457-1463, 2001.
KONNO, K. ; HISADA, M. ; NAOKI, H. ; FONTANA, R. ; YASUHARA, T. ; LORENZI, C. C. B. ; RUGGIERO NETO, J. ; AZEVEDO JR, W. F. ; PALMA, M. S. . Anoplin, a novel antimicrobial peptide from the venom of the solitary wasp Anoplius samariensis. Biochim. Biophys. Acta, v. 1550, p. 70-80, 2001.
SUHARA, Y. ; NIHEI, K. ; KURIHARA, M. ; KITTAKA, A. ; YAMAGUCHI, K. ; FUJISHIMA, T. ; KONNO, K. ; MIYATA, N. ; TAKAYAMA, H. . Efficient and versatile synthesis of novel 2a-substituted 1a,25-dihydroxyvitamin D3 analogues and their docking to vitamin D receptor. J. Org. Chem., v. 66, p. 8760-8771, 2001.
KONNO, K. ; FUJISHIMA, T. ; NAKAGAWA, K. ; TANAKA, M. ; OKANO, T. ; KURIHARA, M. ; MIYATA, N. ; TAKAYAMA, H. . Synthesis and biological evaluation of 5,6-trans-2-methyl-1,25-dihydroxyvitamin D3 and their 20-epimers: possible binding mode of potent A-ring analogues to vitamin D receptor. Chemistry and Biology, v. 8, p. 1011-1024, 2001.
TAKAYAMA, H. ; KONNO, K. ; FUJISHIMA, T. ; MAKI, S. ; LIU, Z. ; CHOKKI, M. ; SMITH, C. ; DELUCA, H. F. ; NAKAGAWA, K. ; OKANO, T. . Systematic studies on synthesis, structural elucidation, and biological evaluation of A-ring diastereomers of 2-methyl-1a,25-dihydroxyvitamin D3 and 20-epi-2-methyl-1a,25-dihydroxyvitamin D3. Steroids, v. 66, p. 277-285, 2001.
YOKOTA, H. ; TSUBOKAWA, H. ; MIYAWAKI, T. ; KONNO, K. ; NAKAYAMA, H. ; MASUZAWA, T. ; KAWAI, N. . Modulation of synaptic transmissions in hippocampal CA1 neurons by a novel neurotoxin (b-PMTX) derived from wasp venom. Neurosci. Res., v. 41, p. 365-371, 2001.
M.-L. Siu-Caldera ; D. S. Rao ; ASTECKER, N. ; A. Weiskopf ; P. Vouros ; KONNO, K. ; FUJISHIMA, T. ; TAKAYAMA, H. ; PELEG, S. ; REDDY, G. S. . Tissue specific metabolism of 1a,25-dihydroxy-20-epi-vitamin D3 into new metabolites with significant biological activity: studies in rat osteosarcoma cells (UMR 106 and ROS 17/2.8). J. Cell. Biochem., v. 82, p. 599-699, 2001.
FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. ; NAKAGAWA, K. ; KUROBE, M. ; OKANO, T. . An efficient synthesis of all A-ring diastereomers of 1a,25-dihydroxyvitamin D3 and its 20-epimer and their biological evaluation. Bioorganic & Medicinal Chemistry , v. 8, p. 123-134, 2000.
NAKAGAWA, K. ; KUROBE, M. ; OZONO, K. ; KONNO, K. ; FUJISHIMA, T. ; TAKAYAMA, H. ; OKANO, T. . Novel ring-A stereoisomers of 2-methyl-1a,25-dihydroxyvitamin D3 and 2-methyl-20-epi-1a,25dihydroxyvitamin D3: Transactivation of target gene and modulation fo differentication in human promyelocytic leukemia (HL-60) cells. Biochemical Pharmacology , v. 59, n.6, p. 691-702, 2000.
KONNO, K. ; HISADA, M. ; NAOKI, H. ; ITAGAKI, Y. ; KAWAI, N. ; MIWA, A. ; YASUHARA, T. ; MORIMOTO, Y. ; NAKATA, Y. . Structure and biological activities of eumenine mastoparan-AF (EMP-AF), a novel mast cell degranulating peptide in the venom of the solitary wasp Anterhynchium flavomarginatum micado. Toxicon , v. 38, p. 1505-1515, 2000.
CANDURI, F. ; DELATORRE, P. ; FADEL, V. ; BIAZI, L. C. C. ; PEREIRA, J. H. ; OLIVIERI, J. R. ; RUGGIERO NETO, J. ; KONNO, K. ; PALMA, M. S. ; YAMANE, T. ; AZEVEDO JR, W. F. . Crystallization and preliminary X-ray diffraction analysis of an eumenine mastoparan toxin. A new class of mast cell degranulating peptide in the wasp venom. Acta Crystallographica. Section B, Structural Science , v. 56, n.D, p. 1434-1436, 2000.
SAHARA, Y. ; GOTOH, M. ; KONNO, K. ; MIWA, A. ; TSUBOKAWA, H. ; ROBINSON, H. ; KAWAI, N. . A new class of neurotoxin from wasp venom slows inactivation of sodium current. European Journal of Neuroscience, v. 12, p. 1961, 2000.
KONNO, K. ; HISADA, M. ; NAOKI, H. ; ITAGAKI, Y. ; YASUHARA, T. ; NAKATA, Y. ; MIWA, A. ; KAWAI, N. . Molecular determinant of binding of a wasp toxin (PMTXs) and its analogs in the Na channels proteins. Neuroscience Letters. Supplement , v. 285, p. 29-32, 2000.
NAKAGAWA, K. ; KUROBE, M. ; KONNO, K. ; FUJISHIMA, T. ; TAKAYAMA, H. ; OKANO, T. . Structure specific control of differentiation and apoptosis of human promyelocytic leukemia (HL-60) cells by A-ring diastereomers of 2-methyl-1a,25-dihydroxyvitamin D3 and its 20-epimer. Biochemical Pharmacology , v. 60, p. 1937-1947, 2000.
SUHARA, Y. ; NIHEI, K. ; TANIGAWA, H. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological evaluation of novel 2a-substituted-1a,25-dihydroxyvitamin D3 analogs. Bioorganic & Medicinal Chemistry Letters , v. 10, p. 1129-1132, 2000.
HISADA, M. ; KONNO, K. ; ITAGAKI, Y. ; NAOKI, H. ; NAKAJIMA, T. . Advantages of using nested collision induced dissociation / post-source decay with matrix-assisted laser desorption / ionization time of flight mass spectrometry: Sequencing of novel peptides from wasp venom. Rapid Commun. Mass Spectr., v. 14, p. 1828-1834, 2000.
KONNO, K. ; MAKI, S. ; LIU, Z. ; FUJISHIMA, T. ; MIURA, D. ; CHOKKI, M. ; ISHIZUKA, S. ; TAKAYAMA, H. . Synthesis, biological activity, and conformational analysis of A-ring diasteromers of 2-methyl-1,25-dihydroxyvitamin D3 and their 20-epimers: Unique activity profiles depending on the stereochemistry of the A-ring and at C-20. Journal of Medicinal Chemistry, v. 43, p. 4247-4265, 2000.
IWASAKI, H. ; HOSOTANI, R. ; NAKANO, Y. ; KONNO, K. ; TAKAYAMA, H. . Improved and efficient synthesis of 1a-hydroxy-[6-2H] and 1a-hydroxy-[6,19,19-2H]vitamin D3. Steroids (Stoneham) , v. 64, p. 396-403, 1999.
KONNO, K. ; MAKI, S. ; TAKAYAMA, H. . Novel oxidation of vitamin D2 by an electrochemical method. Chemical and Pharmaceutical Bulletin , v. 47, n.5, p. 711-712, 1999.
KONNO, K. ; TANIGAWA, H. ; TAKAYAMA, H. . A novel approach to functionalized polycyclic systems; synthesis of tetracyclic comounds by sequential rearrangement-Diels-Alder reaction of 7-oxa-2,3-dimethylenenorbornene derivatives. Heterocycles (Tokyo) , v. 47, n.1, p. 167-170, 1998.
KONNO, K. ; MAKI, S. ; FUJISHIMA, T. ; LIU, Z. ; MIURA, D. ; CHOKKI, M. ; TAKAYAMA, H. . A novel and practical route to A-ring enyne synthon for 1a,25-dihydroxyvitamin D3 analogs: Synthesis of A-ring diastereomers of 1a,25-dihydroxyvitamin D3 and 2-methyl-1,25-dihydroxyvitamin D3. Bioorganic & Medicinal Chemistry Letters , v. 8, n.2, p. 151-156, 1998.
SHIRAHAMA, H. ; KOSHINO, H. ; UZAWA, J. ; YAMANO, K. ; KONNO, K. ; NAKATSU, K. . Tautomerism of clitidine, a pyridine nucleoside from the poisonous mushroom Clitocybe acromelalga. Heterocycles (Tokyo) , v. 47, n.2, p. 661-664, 1998.
MAKI, S. ; KONNO, K. ; OHBA, S. ; TAKAYAMA, H. . Stereoselective chlorination of steroidal 5,6-olefins by an electrochemical method; A convenient synthesis of blattelastanoside B. Tetrahedron Letters , v. 39, p. 3541-3542, 1998.
FUJISHIMA, T. ; LIU, Z. ; MIURA, D. ; CHOKKI, M. ; ISHIZUKA, S. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activity of 2-methyl-20-epi analogues of 1a,25-dihydroxyvitamin D3. Bioorganic & Medicinal Chemistry Letters , v. 8, n.16, p. 2145-2148, 1998.
KONNO, K. ; HARSCH, A. ; TAKAYAMA, H. ; KAWAI, N. ; ROBINSON, H. . Effects of a-pompilidotoxin on synchronized firing in networks of rat cortical neurons. Neuroscience Letters. Supplement , v. 252, p. 49-52, 1998.
KONNO, K. ; HISADA, M. ; ITAGAKI, Y. ; NAOKI, H. ; KAWAI, N. ; MIWA, A. ; YASUHARA, T. ; TAKAYAMA, H. . Isolation and structure of pompilidotoxins (PMTXs), novel neurotoxins in solitary wasp venoms. Biochemical and Biophysical Research Communications , v. 250, n.3, p. 612-616, 1998.
IWASAKI, H. ; MIYAMOTO, Y. ; HOSOTANI, R. ; NAKANO, Y. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological evaluation of (23R)- and (23S)-24,24-difluoro-1a,23,25-trihydroxyvitamin D3. Chemical and Pharmaceutical Bulletin , v. 46, n.12, p. 1932-1935, 1998.
IWASAKI, H. ; HOSOTANI, R. ; MIYAMOTO, Y. ; NAKANO, Y. ; YAMAMOTO, K. ; YAMADA, S. ; SHINKI, T. ; SUDA, T. ; YAMAGUCHI, K. ; KONNO, K. . Stereospecific synthesis and structural establishment of a major metabolite of 24,24-difluoro-1a,25-dihydroxyvitamin D3, (25S)-24,24-difluoro-1a,25,26-trihydroxyvitamin D3. Tetrahedron (Oxford) , v. 54, p. 14705-14724, 1998.
KONNO, K. ; OJIMA, K. ; HAYASHI, T. ; TANABE, M. ; TAKAYAMA, H. . Synthesis and biological acitivity of a 1a,25-dihydroxyvitamin D2 analog bearing an amide group in the side-chain. Chemical and Pharmaceutical Bulletin , v. 45, n.1, p. 185-188, 1997.
KONNO, K. . Poisonous mushrooms. Food Reviews International , v. 13, n.3, p. 471-487, 1997.
MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . Selective oxidation of terminal isopropyl groups to tertiary aldohols by electrochemical methodology. Tetrahedron Letters , v. 38, n.40, p. 7067-7070, 1997.
KONNO, K. ; MIWA, A. ; TAKAYAMA, H. ; HISADA, M. ; ITAGAKI, Y. ; NAOKI, H. ; YASUHARA, T. ; KAWAI, N. . a-Pompilidtoxin (a-PMTX), a novel neurotoxin from the venom of a solitary wasp, facilitates transmission in the crustacean neuromuscular synapse. Neuroscience Letters. Supplement , v. 238, p. 99-102, 1997.
KONDO, F. ; MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . The first synthesis of 24,24-difluoro-1a-hydroxyvitamin D3 by means of radical deoxygenation of alcohols. Chemical and Pharmaceutical Bulletin , v. 44, n.1, p. 62-66, 1996.
HASHIMOTO, K. ; KONNO, K. ; SHIRAHAMA, H. . Simple methods for determining relative stereochemistry of kainoid amino acids by 1H NMR chemical shifts. Journal of Organic Chemistry , v. 61, n.14, p. 4685-4692, 1996.
KONNO, K. ; MAKI, S. ; SAGARA, S. ; TAKAYAMA, H. . Novel approach to functionalized polycyclic systems; Lewis acid induced rearrangements of 7-oxa-2,3-dimethylenenorbornene derivatives. Tetrahedron Letters , v. 36, n.11, p. 1865-1866, 1995.
KONNO, K. . Biologically active components of poisonous mushrooms. Food Reviews International , v. 11, n.1, p. 83-107, 1995.
MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . Oxidation of allylic alcohols by means of electrochemical methodology. Novel rearrangement of prenol under anodic oxidation conditions. Chemistry Letters , p. 559-560, 1995.
MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . A novel approach to functionalized polycyclic systems; new aspects of the Diels-Alder reactions of 2-acyl derivatives of 4H,6H-thieno[3,4-c]-furan 5,5-dioxide. Journal of the Chemical Society, Chemical Communications , p. 2025-2026, 1995.
KONDO, F. ; MIYASHITA, M. ; KONNO, K. ; TAKAYAMA, H. . Facil retro-cycloaddition of adducts derived from steroidal 5,7-dinene and 4-phenyl-1,2,4-triazoline-3,5-dione by diisobutylaluminum hydride. Journal of the Chemical Society-Perkin Transactions 1 , n.21, p. 2679-2680, 1995.
KONNO, K. ; KAWAKAMI, Y. ; HAYASHI, T. ; TAKAYAMA, H. . Regioselective alkylation of 1(3)-acetyl-4H,6H-thieno[3,4-c]-furan 5,5-dioxide. Journal of the Chemical Society-Perkin Transactions 1 , n.11, p. 1371-1373, 1994.
IMAE, Y. ; MANAKA, A. ; YOSHIDA, N. ; ISHIMI, Y. ; SHINKI, T. ; ABE, E. ; SUDA, T. ; KONNO, K. ; TAKAYAMA, H. ; YAMADA, S. . Biological activities of 24-fluoro-1a,25-dihydroxyvitamin D-2 and its 24-epimer. Biochimica and Biophysica Acta , v. 1213, p. 302-308, 1994.
KONNO, K. ; SAGARA, S. ; HAYASHI, T. ; TAKAYAMA, H. . A novel approach to functionalized polycyclic systems; Synthesis of tetracyclic compounds by sequential Diels-Alder reactions of 2-acylated 4H,6H-thieno[3,4-c]-furan 5,5-dioxide. Heterocycles (Tokyo) , v. 39, n.1, p. 51-54, 1994.
HAYASHI, T. ; KAWAKAMI, Y. ; KONNO, K. ; TAKAYAMA, H. . A novel approach to functionalised polycyclic systems; intramolecular Diels-Alder reactions of 2-acylated derivatives of 4H,6H-thieno[3,4-c]-furan 5,5-dioxide. Journal of the Chemical Society-Perkin Transactions 1 , n.20, p. 2387-2388, 1993.
YAMANO, K. ; KONNO, K. ; SHIRAHAMA, H. . A novel excitatory amino acid from Clitocybe acromelalga. A possible intermediate in the biogenesis of acromelic acid A.. Heterocycles (Tokyo) , v. 35, n.1, p. 125-128, 1993.
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. . Synthesis and neuroexcitatory activity of some acromelic acid analogs. Heterocycles (Tokyo) , v. 33, n.1, p. 303-311, 1992.
KONNO, K. ; OJIMA, K. ; HAYASHI, T. ; TAKAYAMA, H. . An alternative and efficient synthesis of 24,24-difluoro-1a,25-dihydroxyvitamin D3. Chemical and Pharmaceutical Bulletin , v. 40, n.5, p. 1120-1124, 1992.
HAYASHI, T. ; OJIMA, K. ; KONNO, K. ; MANAKA, A. ; YAMAGUCHI, K. ; YAMADA, S. ; TAKAYAMA, H. . A new synthesis of 24-fluoro-1a,25-dihydroxyvitamin D2 and its 24-epimer, and determination of the C-24 configuration. Chemical and Pharmaceutical Bulletin , v. 40, n.11, p. 2932-2936, 1992.
YAMANO, K. ; KONNO, K. ; SHIRAHAMA, H. . A new amino acid, L-3-(2-carboxy-4-pyrrolyl)-alanine from the poisonous mushroom Clitocybe acromelalga. Chemistry Letters, p. 1541-1542, 1991.
BULDT, G. ; KONNO, K. ; NAKANISHI, K. ; PLOHN, H. J. ; RAO, B. N. ; DENCHER, N. A. . Heavy-atom labelled retinal analogues located in bacteriorhodopsin by X-ray diffraction. Photochemistry and Photobiology , Great Britain, v. 54, n.6, p. 873-879, 1991.
KONNO, K. ; QIN, G. ; NAKANISHI, K. ; MURATA, M. ; NAYA, Y. . Synthesis of amphiluemin and analogs: A synomone that mediates partner-recognition between anemonefish and sea anemone. Heterocycles (Tokyo) , v. 30, n.1, p. 247-251, 1990.
NAKANISHI, K. ; GOODNOW JR, R. ; KONNO, K. ; NIWA, M. ; BUKOWNIK, R. ; KALIMOPOULOS, T. A. ; USHERWOOD, P. N. R. ; ELDEFRAWI, A. T. ; ELDEFRAWI, M. E. . Philanthotoxin-433 (PhTX-433), a noncompetitive glutamate receptor inhibitor. Pure and Applied Chemistry , v. 62, n.7, p. 1223-1230, 1990.
GOODNOW JR, R. ; KONNO, K. ; NIWA, M. ; KALIMOPOULOS, T. A. ; BUKOWNIK, R. ; LENARES, D. ; NAKANISHI, K. . Synthesis of glutamate receptor antagonist philanthotoxin-433 (PhTX-433) and its analogs. Tetrahedron (Oxford) , v. 46, n.9, p. 3267-3286, 1990.
ANIS, N. A. ; SHERBY, S. ; GOODNOW JR, R. ; NIWA, M. ; KONNO, K. ; KALIMOPOULOS, T. A. ; BUKOWNIK, R. ; NAKANISHI, K. ; USHERWOOD, P. N. R. ; ELDEFRAWI, A. T. ; ELDEFRAWI, M. E. . Structure-activity relationships of philanthotoxin anaolgs and polyamines on N-methyl-D-aspartate and nicotinic acetylcholine receptor. Journal of Pharmacology and Experimental Therapeutics , v. 254, n.3, p. 764-773, 1990.
BRUCE, M. ; BUKOWNIK, R. ; ELDEFRAWI, A. T. ; ELDEFRAWI, M. E. ; GOODNOW JR, R. ; KALIMOPOULOS, T. A. ; KONNO, K. ; NAKANISHI, K. ; NIWA, M. ; USHERWOOD, P. N. R. . Structure-activity relationships of analogues of the wasp toxin philanthotoxin: Noncompetitive anatagonists of quisqualate receptors. Toxicon , v. 28, n.11, p. 1334-1346, 1990.
CHEN, J. G. ; NAKAMURA, T. ; EBREY, T. G. ; OK, H. ; KONNO, K. ; DERGUINI, F. ; NAKANISHI, K. ; HONIG, B. . Wave length regulation of iodopsin, a cone pigment. Biophysical Journal , v. 55, p. 725-729, 1989.
HIRAYAMA, F. ; KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . 4-Aminopyridine-2,3-dicarboxylic acid from Clitocybe acromelalga. Phytochemistry , v. 28, n.4, p. 1133-1135, 1989.
ROZENTAL, R. ; SCOBLE, G. T. ; ALBUQUERQUE, E. X. ; IDRISS, M. ; SHERBY, S. ; SATTELLE, D. B. ; NAKANISHI, K. ; KONNO, K. ; ELDEFRAWI, A. T. ; ELDEFRAWI, M. E. . Allosteric inhibition of nicotinic acetylcholine receptor of vertebrate and insects by philanthotoxin. Journal of Pharmacology and Experimental Therapeutics , v. 249, n.1, p. 123-130, 1989.
HOMMA, Y. ; SATO, Z. ; HIRAYAMA, F. ; KONNO, K. ; SHIRAHAMA, H. ; SUZUI, T. . Production of antibiotics by Pseudomonas cepacia as an agent for biological control of soilborne plant pathogens. Soil Biology & Biochemistry , v. 21, n.5, p. 723-728, 1989.
KENNY, P. T. M. ; GOODNOW JR, R. ; KONNO, K. ; NAKANISHI, K. . Philanthotoxins, a mass spectrometric investigation. Rapid Communication Of Mass Spectrometry, v. 3, n.9, p. 295-297, 1989.
RAGSDALE, D. ; GANT, D. B. ; ANIS, N. A. ; ELDEFRAWI, A. T. ; ELDEFRAWI, M. E. ; KONNO, K. ; MILEDI, R. . Inhibition of rat brain glutamate receptors by philanthotoxin. Journal of Pharmacology and Experimental Therapeutics , v. 251, n.1, p. 156-163, 1989.
KONNO, K. ; HASHIMOTO, K. ; OHFUNE, Y. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Acromelic acids A and B. Potent excitatory amino acids isolated from Clitocybe acromelalga. Journal of the American Chemical Society , v. 110, n.14, p. 4807-4810, 1988.
ELDEFRAWI, A. T. ; ELDEFRAWI, M. E. ; KONNO, K. ; MANSOUR, N. A. ; NAKANISHI, K. ; OLTZ, E. ; USHERWOOD, P. N. R. . Structure and synthesis of a potent glutamate receptor antagonist in wasp venom. PNAS. Proceedings of the National Academy of Sciences of the United States of America , v. 85, p. 4910-4913, 1988.
KONNO, K. ; EISENSTEIN, L. ; LIN, S. ; DOLLINGER, G. ; ODASHIMA, K. ; TERMINI, J. ; DING, W. ; NAKANISHI, K. . FTIR difference studies on apoproteins. Protonation states of aspartic andglutamic acid residues during the photocycles of bacteriorhodopsin. Journal of the American Chemical Society , v. 109, n.22, p. 6860-6862, 1987.
LIN, S. ; ORMOS, P. ; EISENSTEIN, L. ; GOVINDJEE, R. ; KONNO, K. ; NAKANISHI, K. . Deprotonation of tyrosine in bacteriorhodopsin as studied by Fourier transform infrared spectroscopy with deuterium and nitrate labeling. Biochemistry (Easton) , v. 26, n.25, p. 8327-8331, 1987.
KONNO, K. ; HASHIMOTO, K. ; OHFUNE, Y. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Synthesis of acromelic acid A, a toxic principle of Clitocybe acromelalga. Tetrahedron Letters , v. 27, n.5, p. 607-610, 1986.
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Improved procedures for preparation of 2-pyridones and 2-hydroxy methylpyridines from pyridine N-oxide. Heterocycles (Tokyo) , v. 24, n.8, p. 2169-2172, 1986.
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . A new pyridine synthesis starting from a,b-unsaturated carbonyl compounds. Tetrahedron Letters , v. 27, n.33, p. 3865-3868, 1986.
HASHIMOTO, K. ; KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Synthesis of acromelic acid B, a toxic principle of Clitocybe acromelalga. Chemistry Letters , p. 1399-1400, 1986.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Clithioneine, an amino acid betaine from Clitocybe acromelalga. Phytochemistry , v. 23, n.5, p. 1003-106, 1984.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Isolation and structureof acromelic acid A and B. New kainoids of Clitocybe acromelalga. Tetrahedron Letters , v. 24, n.9, p. 939-942, 1983.
KONNO, K. ; HAYANO, K. ; SHIRAHAMA, H. ; SAITOH, H. ; MATSUMOTO, T. . Clitidine, a new toxic pyridine nucleoside from Clitocybe acromelalga. Tetrahedron (Oxford) , v. 38, n.22, p. 3281-3284, 1982.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Synthesis of 2-aminothiazolyl analog of ergothioneine. Heterocycles (Tokyo) , v. 15, n.2, p. 1033-1036, 1981.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Isolation and structure of clithioneine, a new amino acid betaine from Clitocybe acromelalaga. Tetrahedron Letters , v. 22, n.17, p. 1617-1618, 1981.
KONNO, K. ; HAYANO, K. ; SHIRAHAMA, H. ; SAITOH, H. ; MATSUMOTO, T. . Structure and synthesis of clitidine, a new pyridine nucleoside from Clitocybe acromelalga. Tetrahedron Letters , n.5, p. 481-482, 1977.
NAGASWA, E. ; KONNO, K. . Poisonous fugi in Japan. Tokyo, Japão: Eiji Nagasawa, 2003. v. 13.
KONNO, K. . Streitwieser, Introduction to Organic Chemistry. 4. ed. Tokyo: Yasuhide Yukawa, 1995. v. 2. 1362p .
KONNO, K. . Chemistry and Biochemistry on Mushrooms. Tokyo: Takashi Mizuno, Masamitu Kawai, 1992. 99p .
KONNO, K. . Chemistry and Biochemistry on Mushrooms. Tokyo: Takashi Mizuno, Masamitsu Kawai, 1992. 111p .
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. . Mushroom toxins. Life Sciences for Nutrition and Health, Tokyo, , v. 4, p. 203 - 209, 20 jul. 1999.
KONNO, K. . Glutamate antagonist in wasp venom. Kagaku to Seibutsu (Chemistry and Biology), Tokyo, , v. 31, p. 755 - 760, 25 nov. 1993.
KONNO, K. ; SHIRAHAMA, H. . Acromelic acids, potent neuroexcitatory mushroom toxin from Clitocybe acromelalga. Kagaku to Sibutsu (Chemistry and Biology), Tokyo, , v. 25, p. 480 - 484, 25 jul. 1987.
KONNO, K. . Toxic principles from the fungus Clitocybe acromelalga (Dokusasako). Nipponn Nogeikagaku Kaishi (Journal of the Japan Society for Bioscience, Biotechnology, and Agrochemisrty, Tokyo, , v. 63, p. 876 - 879.
KONNO, K. . Toxins in mushrooms. Gekkan Fudo Kemikaru (Food Chemicals, Monthly Journal), Tokyo, , v. 1993-1, p. 54 - 67.
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. . Mushroom toxins. Chemsitry Today.
KONNO, K. . Bioactive substances in solitary wasp venoms. BIO Clinica, , v. 16, p. 18 - 22.
KONNO, K. . Research and education of pharmaceutical sciences in Brazil. Farumashia, Tokyo, p. 50 - 51.
KONNO, K. . Potent analgesic peptide form the venom of South American rattlesnake. Kagaku to Seibutsu (Chemistry and Biology), Tokyo/Japão, p. 2 - 4.
KAZUMA, K. ; KONNO, K. . Jiryu and the identification of earthworm. Wakanyaku, Tokyo/Japão, p. 3 - 4.
KONNO, K. ; SATAKE, M. . Food poisoning by Hydrangea plants and its toxic components. Food Hygiene and Safety Science, Tokyo/Japão, p. J6 - J9.
KONNO, K. ; SHIAVON, E. ; STEVENS, M. ; ZAHARENKO, A. J. ; TYTGAT, J. ; WANKE, E. ; KAWAI, N. . Pompilidotoxins, peptide neurotoxins in solitary wasp venom blocking sodium channel inactication. In: 46th Japanese Peptide Symposium, 2009, Kokura, Japão. 46th Japanese Peptide Symposium. Fukuoka, Japão: Kouji Okamoto, 2009. p. 75-76.
KONNO, K. ; PICOLO, G. ; GUTIERREZ, V. P. ; BRIGATTE, P. ; ZAMBELLI, V. O. ; CAMARGO, A. C. M. ; CURY, Y. . Crotalphine, a highly potent analgesic peptide from the venom of the south American rattlesnake Crotalus durissus terrificus. In: 45th Japanes Peptide Symposium, 2008, Tokyo, Japão. Peptide Science 2008. Tokyo, Japã: Motoyoshi Nomizu, 2008. p. 107-108.
KONNO, K. . Neuropeptides found in the venom of solitary wasp. In: Invertebrate Neuropeptide Conference, 2011, Kota Kinabalu/Malasia. Invertebrate Neuropeptide Conference 2011. College Station, TX/EUA: Ronald J. Nachman, 2011. p. 2.
HONMA, M. ; NOGUCHI, S. ; TANAKA, K. ; KONNO, K. ; HASHIMOTO, M. . Isolation and structure determination of anitmicrobila depsipeptide. In: Annual Meeting of JSBBA 2011, 2011, Kyoto/Japão. Annual Meeting of JSBBA 2011, 2011. p. 2A04p13.
KONNO, K. ; NIHEI, K. ; ANDO, K. ; KAZUMA, K. ; SATAKE, M. . Novel peptides found in the venoms of solitary digger wasps. In: Annual Meeting of the Pharmaceutical Society of Japan, 2011, Shizuoka/Japão. 131th Annual Meeting of the Pharmaceutical Society of Japan, 2011. p. 31P-0682.
Miyanaga, S. ; KAZUMA, K. ; KONNO, K. ; ISHIKAWA, N. K. ; NAGASWA, E. ; TOKIMOTO, K. ; SATAKE, M. . Isolation and structure determination of novel phenanthrene compound from Lentinus strigosus. In: Annual Meeting of the Pharmaceutical Society of Japan, 2011, Shizuoka/Japão. 131th Annual Meeting of the Pharmaceutical Society of Japan, 2011. p. 31P-0622.
KAZUMA, K. ; Miyanaga, S. ; KONNO, K. ; SATAKE, M. . The bitter components of Sweet Hydrangea leaf. In: Annual Meeting of the Pharmaceutical Society of Japan, 2011, Shizuoka/Japão. 131th Annual Meeting of the Pharmaceutical Society of Japan, 2011. p. 31G-am01.
KONNO, K. ; KAZUMA, K. ; SATAKE, M. ; MURAKAMI, T. ; HASHIMOTO, M. ; ZAHARENKO, A. J. ; FERREIRA JR., W. A. ; FREITAS, J. C. ; PICOLO, G. ; CURY, Y. . Bunodosine 391, a novel acylamino acid from the venom of the South American sea anemone Bunodosoma cangicum. In: 130th Annual Meeting of the Pharmaceutical Society of Japan, 2010, Okayama, Japão. 130th Annual Meeting of the Pharmaceutical Society of Japan, 2010. p. 29TN-pm05.
KAZUMA, K. ; KONNO, K. ; SATAKE, M. . Preparation of pharmacopeia for Myanmar herbal medicine. In: The 57th Annual Meeting of the Japanese Society of Pharmacognosy, 2010, Tokushima, Japão. The 57th Annual Meeting of the Japanese Society of Pharmacognosy. Tokushima, Japão: Yoshinori Asakawa, 2010. p. 216.
Miyanaga, S. ; KAZUMA, K. ; KONNO, K. ; SATAKE, M. . Food poisoning by Hydrangea plants. In: The 57th Annual Meeting of the Japanese Society of Pharmacognosy, 2010, Tokushima, Japão. The 57th Annual Meeting of the Japanese Society of Pharmacognosy. Tokushima, Japão: Yoshinori Asakawa, 2010. p. 343.
ISOBE, Y. ; Miyanaga, S. ; KAZUMA, K. ; KONNO, K. ; SATAKE, M. . Chemical constituents of hawthorn. In: The 57th Annual Meeting of the Japanese Society of Pharmacognosy, 2010, Tokushima, Japão. The 57th Annual Meeting of the Japanese Society of Pharmacognosy. Tokushima, Japão: Yoshinori Asakawa, 2010. p. 355.
KONNO, K. ; KAZUMA, K. ; ANDO, K. ; SATAKE, M. ; YASUMOTO, K. ; SEKITA, S. ; NIHEI, K. ; KATO, M. ; RANGEL, M. ; CABRERAA, M. P. S. . Structure and biological activies of novel antimicrobial peptides isolated from solitary wasp venoms. In: The 57th Annual Meeting of the Japanese Society of Pharmacognosy, 2010, Tokushima, Japão. The 57th Annual Meeting of the Japanese Society of Pharmacognosy. Tokushima, Japão: Yoshinori Asakawa, 2010. p. 377.
ANDO, K. ; Miyanaga, S. ; KAZUMA, K. ; KONNO, K. ; SATAKE, M. . Structure determination of xylocopin, a peptide toxin in the venom of a carpenter bee. In: The 57th Annual Meeting of the Japanese Society of Pharmacognosy, 2010, Tokushima, Japão. The 57th Annual Meeting of the Japanese Society of Pharmacognosy. Tokushima, Japão: Yoshinori Asakawa, 2010. p. 378.
KONNO, K. ; PICOLO, G. ; GUTIERREZ, V. P. ; BRIGATTE, P. ; ZAMBELLI, V. O. ; CAMARGO, A. C. M. ; CURY, Y. . Crotalphine, a highly potent analgesic peptide form the venom of the South American rattlesnake Crotalus durssus terrificus. In: 50th Symposium on the Chemistry of Natural Products, 2008, Fukuoka, Japão. 50th Symposium on the Chemistry of Natural Products, 2008. p. 409-413.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; LIMA, C. ; BRUNI, F. M. ; PAREJA-SANTOS, A. ; ANTONIAZZI, M. M. ; JARED, C. ; GILIO, J. M. ; SILVA, C. A. ; CONCEICAO, I. M. ; SCIANI, J. ; LOPES-FERREIRA, M. ; BORELLA, M. ; PREZOTO, B. C. . Biological effect driven biochemical assessment of the sikin secretion of Phyllomedusa hypochondrialis. In: XXXVI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2007, Salvador. Resumo, 2007. p. S-28.
KONNO, K. ; ZAHARENKO, A. J. ; FERREIRA JR., W. A. ; OLIVEIRA, J. S. ; RICHARDSON, M. ; PIMENTA, D. C. ; PORTARO, F. C. V. ; FREITAS, J. C. . Proteomics of the neurotoxic fractions from the sea anemones Bunodosoma cangicum and Bunodosoma caissarum venoms: novel peptides belonging to new class of toxins. In: 9th Pan-American Section Congress of the International Society of Toxinology, 2007, Juriquilla. Abstracts, 2007. p. 16.
ZAHARENKO, A. J. ; FERREIRA JR., W. A. ; AOKI, R. K. ; KONNO, K. ; FREITAS, J. C. . Low molecular weight components from sean anemone venoms: a neglected field of investigation. In: 9th Pan-American Section Congress of the International Society of Toxinology, 2007, Juriquilla. Abstracts, 2007. p. 46.
FERREIRA JR., W. A. ; ZAHARENKO, A. J. ; GUTIERREZ, V. P. ; KONNO, K. ; FREITAS, J. C. ; PICOLO, G. ; CURY, Y. . Analgesic effect induced by the compound LAS390 purified from sea anemone Bunodosoma cangicum venom. In: 9th Pan-American Section Congress of the International Society of Toxinology, 2007, Juriquilla. Abstracts, 2007. p. 118.
FERREIRA JR., W. A. ; ZAHARENKO, A. J. ; GUTIERREZ, V. P. ; KONNO, K. ; FREITAS, J. C. ; PICOLO, G. ; CURY, Y. . Analgesic effect induced by the compound LAS390 purified from sea anemone Bunodosoma cangicum venom. In: 9th Pan-American Section Congress of the International Society of Toxinology, 2007, Juriquilla. Abstracts, 2007. p. 118.
KONNO, K. ; PICOLO, G. ; GUTIERREZ, V. P. ; BRIGATTE, P. ; ZAMBELLI, V. O. ; CAMARGO, A. C. M. ; CURY, Y. . Crotalphine, a novel and potent analgesic peptide from the venom of the South American rattlesnake Crotalus durissus terrificus. In: ICOB-5 & ISCNP-25 IUPAC, International Conference on Biodiversity and Natural Products, 2006, Kyoto. ICOB-5 & ISCNP-25 IUPAC, International Conference on Biodiversity and Natural Products, Abstracts, 2006. p. P-85.
CARVALHO, L. R. ; PIPOLE, F. ; WERNER, V. R. ; LAUGHINGHOUSE, H. D. ; CAMARGO, A. C. M. ; RANGEL, M. ; KONNO, K. ; SANTANNA, C. L. . Estudos biológicos e químicos de floração de cianobactérias ocorrida na Lagoa do Violão, Torres, RS. In: IX Congresso Brasileiro de ficologia & simpósio Latino-Americano sobre algas nocivas, 2006, Itajaí. Resumo, 2006.
FLORES, M. P. A. ; FRITZEN, M. ; REI, C. V. ; KONNO, K. ; CHUDZINSKI-TAVASSI, A. M. . Pathophysiological mechanisms, sequence analysis and prediction of tertiary structure of Losac, a factor X activator from Lonomia Obliqua bristles extract. In: XXXV Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2006, Águas de Lindóia. Programa, 2006. p. N-28.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; ANTONIAZZI, M. M. ; JARED, C. ; LOPES-FERREIRA, M. ; PIMENTA, D. C. . Proteomic analysis of low molecular weight peptides from the skin secretions of Phyllomedusa hypochondrialis. In: XXXV Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2006, Águas de Lindóia. Resumo, 2006. p. S-33.
KONNO, K. . Marine peptide sequence determination using mass spectrometry analyses. In: XXI Reunião da Federação de Sociedades de Biologia Experimental (FeSBE), 2006, Águas de Lindóia. Resumo, 2006.
FERREIRA JR., W. A. ; OLIVEIRA, J. S. ; ZAHARENKO, A. J. ; SHIDA, C. S. ; KONNO, K. ; RICHARDSON, M. ; LUCIO, A. D. ; BEIRAO, P. S. L. ; FREITAS, J. C. . Modelo estrutural do peptídeo neurotóxico, BcIV, da anêmona do mar Bunodosoma caissarum-Possíveis contribuições de cargas de aminoácidos para a interação com sítios receptors. In: XXI Reunião da Federação de Sociedades de Biologia Experimental (FeSBE), 2006, Águas de Lindóia. Programa, 2006.
ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; FREITAS, J. C. ; KONNO, K. ; PORTARO, F. C. V. ; RICHARDSON, M. ; SANTANNA, O. A. ; TAMBOURGI, D. V. . Caissarolysin I (Bcs I), a new hemolytic toxin from the Brazilian sea anemone Bunodosoma caissarum: purification and biological characterization. In: XXI Reunião da Federação de Sociedades de Biologia Experimental (FeSBE), 2006, Águas de Lindóia. Programa, 2006.
GREGGIO, S. ; SALAMONI, S. D. ; VENTURIN, G. T. ; ALENCAR, A. ; ABREU, D. S. ; CUNHA, F. B. ; OLIVEIRA, R. M. ; BREDA, R. V. ; COSTA, J. C. ; CAMMAROTA, M. ; PALMA, M. S. ; KONNO, K. ; NIHEI, K. . Antiepileptiform activity of the acylpolyaminetoxin JSTX-3 on rat CA1 neurons. In: XXI Reunião da Federação de Sociedades de Biologia Experimental (FeSBE), 2006, Águas de Lindóia. Programa, 2006.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; ANTONIAZZI, M. M. ; JARED, C. ; LOPES-FERREIRA, M. ; PIMENTA, D. C. . Isolation and characterization of new bradykinin related peptides from the skin secretion of Phyllomedusa hypochondrialis. In: IX Congresso Brazileiro de Toxinologia, 2006, Fortaleza. Resumo, 2006. p. AF005.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; ANTONIAZZI, M. M. ; JARED, C. ; SCIANI, J. M. ; CONCEICAO, I. M. ; PREZOTO, B. C. ; CAMARGO, A. C. M. ; PIMENTA, D. C. . Isolation and characterization of a novel bradykinin potentiating peptide from the skin secretion of Phyllomedusa hypochondrialis. In: IX Congresso Brazileiro de Toxinologia, 2006, Fortaleza. Resumo, 2006. p. AF006.
ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; FERREIRA JR., W. A. ; KONNO, K. ; SHIDA, C. S. ; RICHARDSON, M. ; LUCIO, A. D. ; BEIRAO, P. S. L. ; FREITAS, J. C. . BcIV, a new paralyzing peptide from the venom of the sea anemone Bunodosoma caissarum. A comparison with the Na+ channel toxin BcIII. In: IX Congresso Brazileiro de Toxinologia, 2006, Fortaleza. Resumo, 2006. p. AM004.
OLIVEIRA, J. S. ; ZAHARENKO, A. J. ; FREITAS, J. C. ; KONNO, K. ; ANDRADE, S. A. ; PORTARO, F. C. V. ; RICHARDSON, M. ; SANTANNA, O. A. ; TAMBOURGI, D. V. . Caissarolysin I (Bcs I), a new hemolytic toxins from the Brazilian sea anemone Bunodosoma caissarum: purification and biological characterization. In: IX Congresso Brazileiro de Toxinologia, 2006, Fortaleza. Resumo, 2006. p. AM008.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; MARQUES, E. E. ; HIRUMA-LIMA, C. A. ; RICHARDSON, M. ; PIMENTA, D. C. ; LOPES-FERREIRA, M. . Orpotrin: a novel casoconstrictor peptide from the venom of the Brazilian stingray Potamotrygon gr. orbgnyi. In: IX Congresso Brazileiro de Toxinologia, 2006, Fortaleza. Resumo, 2006. p. AM014.
FERREIRA JR., W. A. ; PICOLO, G. ; ZAHARENKO, A. J. ; GUTIERREZ, V. P. ; KONNO, K. ; FREITAS, J. C. ; CURY, Y. . Analgesic effects of a fraction (BcgNN) obtained from the sea anemone Bunodosoma cangicum venom. In: IX Congresso Brazileiro de Toxinologia, 2006, Fortaleza. Resumo, 2006. p. AM018.
PEREIRA, L. ; PICOLO, G. ; BRIGATTE, P. ; CURY, Y. ; KONNO, K. . Evaluation of the development of delayed hyperalgesia by crotalphine, an analgesic opioid obtained from C. d. terrificus. In: IX Congresso Brazileiro de Toxinologia, 2006, Fortaleza. Resumo, 2006. p. SP127.
KONNO, K. . Peptide toxins from Brazilian biodiversity. In: IX Congresso Brazileiro de Toxinologia, 2006, Fortaleza. Resumo, 2006. p. AM018.
RIOLI, V. ; FERNANDEZ, A. J. H. ; PREZOTO, B. C. ; KONNO, K. ; MELO, R. L. ; KLITZKE, C. F. ; LOPES-FERREIRA, M. ; FERRO, E. S. ; CAMARGO, A. C. M. ; PORTARO, F. C. V. . Discovery of two new pharmacological activities for proline rich peptides in Bothrops jararaca venom. In: XIII Reunião Científica Anual, 2006, São Paulo. Memórias do Instituto Butantan, 2006. v. 63. p. 19.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; ANTONIAZZI, M. M. ; JARED, C. ; LOPES-FERREIRA, M. ; PIMENTA, D. C. . Proteomic analysis of low molecular weight peptides from the skin secretion of Phyllomedusa hypochondrialis. In: XIII Reunião Científica Anual, 2006, São Paulo. Memórias do Instituto Butantan, 2006. v. 63. p. 39.
CONCEICAO, K. ; KONNO, K. ; MELO, R. L. ; ANTONIAZZI, M. M. ; JARED, C. ; GILIO, J. M. ; SILVA, C. A. ; LOPES-FERREIRA, M. ; BORELLA, M. I. ; CAMARGO, A. C. M. ; PIMENTA, D. C. . Identification of novel bradykinin potentiating peptide (BPP) from the skin secretion of Phyllomedusa hypochondrialis. In: XIII Reunião Científica Anual, 2006, São Paulo. Memórias do Instituto Butantan, 2006. v. 63. p. 39.
PFISTER, S. C. ; RANGEL, M. ; PRADO, M. P. ; FERRIRA, R. A. S. ; KONNO, K. ; SANTELLI, G. M. M. . Effects of sponge peptides on gap junction channels in liver cells. In: XIII Reunião Científica Anual, 2006, São Paulo. Memórias do Instituto Butantan, 2006. v. 63. p. 44.
FERREIRA JR., W. A. ; ZAHARENKO, A. J. ; GUTIERREZ, V. P. ; KONNO, K. ; FREITAS, J. C. ; PICOLO, G. ; CURY, Y. . Analgesic effects of a fraction (BcgNN) obtained from the sea anemone Bunodosoma cangicum venom. In: XIII Reunião Científica Anual, 2006, São Paulo. Memórias do Instituto Butantan, 2006. v. 63. p. 45.
SIMONS, M. S. ; BATISTA, I. F. C. ; LOPES, A. ; KONNO, K. ; CHUDZINSKI-TAVASSI, A. M. . Comparative study of native and recombinant forms of FXa inhibitor, from Amblyomma cajennense (Acari: Ixodida). In: XIII Reunião Científica Anual, 2006, São Paulo. Memórias do Instituto Butantan, 2006. v. 63. p. 113.
SANTOS, E. J. C. ; KONNO, K. ; HAYASHI, M. A. F. ; MAMBELLI, L. O. ; YAMANE, T. ; PEREIRA, A. ; SANTOS, R. C. S. ; KERKIS, A. ; KERKIS, I. . Crotamine nuclear localization sequence mediate gene delivery into cells. In: XIII Reunião Científica Anual, 2006, São Paulo. Memórias do Instituto Butantan, 2006. v. 63. p. 113.
KONNO, K. ; CAONCEICAO, K. ; JARED, C. ; SANTANNA, O. A. ; DAFFRE, S. ; CAMARGO, A. C. M. ; PIMENTA, D. C. . Isolation and biochemical characterization of peptides presenting antimicrobial actitivy from the skin of Phyllomedusa hypochondrialis. In: XXIX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2005, Águas de Lindoia. XXIX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2005.
KONNO, K. ; CABRERA, M. P. ; PALMA, M. S. ; AZEVEDO JR, W. F. ; RUGGIERO NETO, J. . Conformational analysis, lytic and biological activity of bioactive peptides. In: Biophysical Society 49th Annual Meeting, 2005, Long Beach. Biophys. J., 2005. p. 251A.
ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; FERREIRA JR., W. A. ; KONNO, K. ; RICHARDSON, M. ; FREITAS, J. C. . Critical amino acid positions in type 1 sodium channel toxins from the sea anemone Bunodosoma cangicum venom. In: 7th Asia-Pacific Congress on Animal, Plant and Microbial Toxins, 2005, Cebu. 7th Asia-Pacific Congress on Animal, Plant and Microbial Toxins, 2005.
KONNO, K. ; PIMENTA, D. C. ; SERRANO, S. ; CAMARGO, A. C. M. . Proteomic approaches to identify and characterize toxins in animal venoms and secretions based on liquid chromatographic separations. In: XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2004, Caxambu. XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2004. p. SP.02.
KONNO, K. ; RICCI-SILVA, M. E. ; FARIA, F. ; YAMANE, T. ; CHUDZINSKI-TAVASSI, A. M. . Proteomics and molecular biology analysis of the salivary gland of Haementeria depressa leech. In: XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2004, Caxambu. XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2004. p. H-6.
KONNO, K. ; HAYASHI, M. A. F. ; CAMARGO, A. C. M. ; ULRICH, H. . BPP s counteract inhibition of the nicotinic acetylcoloine receptor by the noncompetitive inhibitor MK-801. In: XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2004, Caxambu. XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2004. p. P-14.
KONNO, K. ; BRAGA, M. C. V. ; PORTARO, F. C. V. ; PIMENTA, D. C. ; J. C. Freitas ; YAMANE, T. . Biochemical characterization of a novel two-disulfide-bridge peptide from Conus regius venom. In: XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2004, Caxambu. XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2004. p. S-9.
KONNO, K. ; IANZER, D. ; MARQUES-PORTO, R. ; PORTARO, F. C. V. ; STOCKLIN, R. ; CAMARGO, A. C. M. ; PIMENTA, D. C. . Identification of five new bradykinin potentiating peptides (BPPs) from Bothrops jararaca crude venom by using electrospray ionization tandem mass spectrometry after a two-step liquid chromatography. In: XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2004, Caxambu. XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2004. p. S-13.
KONNO, K. ; CABRERA, M. P. ; PALMA, M. S. ; AZEVEDO JR, W. F. ; RUGGIERO NETO, J. . Pore forming peptides from solitary wasp venoms structure activity relationships. In: XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2004, Caxambu. XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2004. p. S-23.
KONNO, K. ; PEREIRA, L. S. ; M. J. Kato ; DAFFRE, S. . Chemical synthesis of mygalin, an antibacterial acypolyamine from hemocyte of the tarantula spider A. gomesiana. In: XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2004, Caxambu. XXXIII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2004. p. S-33.
KONNO, K. ; ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; PIMENTA, D. C. ; J. C. Freitas ; WANKE, E. . Nav 1.1-1.6 sodium channels binding specificity to sea anemone toxins: unexpected contributions from changes in the IV/S3-S4. In: VIII Simpósio da Sociedade Brasileira de Toxinologia, 2004, Angra dos Reis. VIII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2004. p. 42.
KONNO, K. ; J. C. Freitas ; RANGEL, M. ; BRAGA, M. C. V. ; OLIVEIRA, J. S. ; ZAHARENKO, A. J. ; WANKE, E. . An outline on marine toxins found in organisms of Brazilina coast. In: VIII Simpósio da Sociedade Brasileira de Toxinologia, 2004, Angra dos Reis. VIII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2004. p. 44.
KONNO, K. ; BRAGA, M. C. V. ; PIMENTA, D. C. ; J. C. Freitas ; PORTARO, F. C. V. ; YAMANE, T. . Characterization of a P-superfamily peptide from Conus regius venom. In: VIII Simpósio da Sociedade Brasileira de Toxinologia, 2004, Angra dos Reis. VIII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2004. p. 140.
KONNO, K. ; ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; PIMENTA, D. C. ; HIRATA, I. ; J. C. Freitas . Proteomics of the neurotoxic fraction from the sea anemone Bunodosoma cangicum. Novel peptides belonging to a new class of neurotoxins. In: VIII Simpósio da Sociedade Brasileira de Toxinologia, 2004, Angra dos Reis. VIII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2004. p. 137.
KONNO, K. ; OLIVEIRA, J. S. ; ZAHARENKO, A. J. ; J. C. Freitas . A new peptide isolated from the neurotoxic fraction of Bunodosoma caissarum venom has a BcIII-like action on the crab nerve. In: VIII Simpósio da Sociedade Brasileira de Toxinologia, 2004, Angra dos Reis. VIII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2004. p. 137.
KONNO, K. ; FLORES, M. P. A. ; CHUDZINSKI-TAVASSI, A. M. . Effects of Losaic (a factor X activator from Lonomia obliqua caterpillar) on huvecs and sequencing. In: VIII Simpósio da Sociedade Brasileira de Toxinologia, 2004, Angra dos Reis. VIII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2004. p. 151.
KONNO, K. ; FARIA, F. ; RICCI-SILVA, M. E. ; LEE HO, P. ; YAMANE, T. ; CHUDZINSKI-TAVASSI, A. M. . Identification of new proteins involved in feeding process from Haementeria depressa leach salivary complexes by transcriptomic and proteominc analysis. In: VIII Simpósio da Sociedade Brasileira de Toxinologia, 2004, Angra dos Reis. VIII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2004. p. 177.
KONNO, K. ; SALAMONI, S. D. ; COSTA, J. C. ; PALMA, M. S. ; TAVARES, A. A. ; ABREU, D. S. ; VENTURIN, G. T. ; BREDA, R. V. . Antiepileptic effect of the acylpolyaminetoxin JSTX-3 in human hippocampal CA1 neurons in vitro. In: American Epilepsy Society 58th Annual Meeting, 2004, New Orlearns. Epilepsia, 2004. v. 45. p. 31.
KONNO, K. ; HASHIMOTO, K. ; YAMADA, M. ; TOKUMITSU, N. ; SAIKAWA, Y. ; ASANO, J. ; MIYAIRI, K. ; OKUNO, T. ; AKDA, M. N. . Molybdophyllysin, a Toxic Metalloendopeptidase from a Tropical Toadstool, Chlorophyllum molybdites. In: 46th Symposium on Natural Products Chemistry, 2004, Hiroshima. Abstract Papers, 46th Symposium on Natural Products Chemistry, 2004. p. 515-520.
KONNO, K. ; PEREIRA, L. S. ; SILVA, P. I. ; NAOKI, H. ; MIRANDA, M. T. M. ; ALMEIDA, I. C. ; DAFFRE, S. . Isolation and structure of mygalin, an antibacterial polyamine from spider hemolymph. In: XXXII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2003, Caxambu. XXXII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2003. p. 231.
KONNO, K. ; CABRERA, M. P. ; PALMA, M. S. ; AZEVEDO JR, W. F. ; RUGGIERO NETO, J. . Eumenine mastoparans structure activity relationships. In: XXXII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2003, Caxambu. XXXII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2003. p. 235.
KONNO, K. ; CABRERA, M. P. ; PALMA, M. S. ; AZEVEDO JR, W. F. ; RUGGIERO NETO, J. . Structure activity relationships among short chain peptides. In: XXXII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2003, Caxambu. XXXII Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2003. p. 236.
KONNO, K. ; M. J. Kato ; YAMANE, T. ; PALMA, M. S. . An eficient and versatile synthesis of acylpolyamine spider toxins. In: 10th Brazilian Meeting on Organic Synthesis (BMOS-10), 2003, São Pedro. 10th Brazilian Meeting on Organic Synthesis (BMOS-10), Abstract Book, 2003. p. 72.
KONNO, K. ; OLIVEIRA, J. S. ; ZAHARENKO, A. J. ; TAMBOURGI, D. V. ; PORTARO, F. C. V. ; PIMENTA, D. C. ; HIRATA, I. ; YAMANE, T. ; J. C. Freitas . Toxinas de duas espéies de anêmonas do mar do litoral sudeste brasileiro. In: XVIII Reunião Annual da Federação Sociedades de Biologia Experimental, 2003, Curitiba. XVIII Reunião Annual da Federação Sociedades de Biologia Experimental, Resumos, 2003.
KONNO, K. ; RICCI-SILVA, M. E. ; YAMANE, T. ; CHUDZINSKI-TAVASSI, A. M. . Two-dimensional electrophoresis and mass spectrometry analysis of the salivary gland of Haementeria depressa leech. In: V Reunião Annual do Instituto Butantan, 2003, São Paulo. V Reunião Annual do Instituto Butantan, Resumo, 2003. p. 010.
KONNO, K. ; LAMEU, C. ; RADIS-BAPTISTA, G. ; YAMANE, T. ; CAMARGO, A. C. M. ; HAYASHI, M. A. F. . BPPs presursor from the venom of Crotalus durisus terrificus. In: V Reunião Annual do Instituto Butantan, 2003, São Paulo. V Reunião Annual do Instituto Butantan, Resumo, 2003. p. 014-A.
KONNO, K. ; LAMEU, C. ; RADIS-BAPTISTA, G. ; YAMANE, T. ; CAMARGO, A. C. M. ; HAYASHI, M. A. F. . BPPs presursor from the venom of Crotalus durisus terrificus. In: V Reunião Annual do Instituto Butantan, 2003, São Paulo. V Reunião Annual do Instituto Butantan, Resumo, 2003. p. 014-A.
KONNO, K. ; RANGEL, M. ; PRADO, M. P. ; PROCOPIO, J. ; NAOKI, H. ; J. C. Freitas . Anti-proliferative haemolytic substances of the marine sponge Geodia corticostylifera from Brazilian coast. In: International Symposium on Chemistry and Biology of Marine Organisms, 2003, Kolympari/Crete/Greece. International Symposium on Chemistry and Biology of Marine Organisms, 2003.
KONNO, K. ; ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; J. C. Freitas ; TAMBOURGI, D. V. ; SANTANNA, O. A. ; PIMENTA, D. C. ; PORTARO, F. C. V. ; YAMANE, T. . Purification of neurotoxic peptides from the sea anemone Bundosoma cangicum and recognition of its cytolytic fraction by anti-equinatoxin-II polyclonal antibodies. In: 14th World Congress on Animal, Plant & Microbial Toxins, 2003, Adelaide/Australia. 14th World Congress on Animal, Plant & Microbial Toxins, 2003.
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. . Poisonous mushrooms as a resource of biomedical application. In: The 10th International Symposium on New Materials Development from Plant for Natural Anti-Cancer Resources, 2003, Man Hae Village/Korea. The 10th International Symposium on New Materials Development from Plant for Natural Anti-Cancer Resources, Abstracts, 2003. p. 1.
KONNO, K. ; ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; J. C. Freitas ; PIMENTA, D. C. . Purification and preliminary electrophysiological characterization of a neurotoxin from the sea anemone Bunodosoma cangicum. In: V Ibero-American Congress of Biophysics, 2003, Rio de Janeiro. V Ibero-American Congress of Biophysics, 2003.
LORENZI, C. C. B. ; CABRERA, M. P. ; AZEVEDO JR, W. F. ; PALMA, M. S. ; KONNO, K. ; RUGGIERO NETO, J. . Conformation analysis of eumenine mastoparans from the solitary wasp Anterhynchium flavomarginatum micado. In: XXXI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2002, Caxambu. XXXI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2002. p. 219.
KONNO, K. ; HIRATA, I. ; M. A. Juliano ; STOCKLIN, R. ; HISADA, M. ; NAOKI, H. ; YASUHARA, T. ; L. Juliano ; NAKAJIMA, T. ; PALMA, M. S. . Peptide neurotoxins in solitary wasp venoms. In: XXXI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2002, Caxambu. XXXI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2002. p. 219.
SOUZA, B. M. ; CESAR, L. M. M. ; MENDES, M. A. ; MARQUES, M. R. ; KONNO, K. ; PALMA, M. S. . Biochemical characterization of three new biologically active peptides from Polybia paulista venom. In: XXXI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2002, Caxambu. XXXI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos. p. 219.
FONTANA, R. ; MALASPINA, O. ; KONNO, K. ; PALMA, M. S. . Jelleines. Antimicrobial peptides from royal jelly of Apis mellifera. In: XXXI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2002, Caxambu. XXXI Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2002. p. 219.
KONNO, K. ; SOUZA, B. M. ; FONTANA, R. ; HIRATA, I. ; M. A. Juliano ; L. Juliano ; PALMA, M. S. . Novel antimicrobial peptides from the venoms of solitary eumenid wasps. In: VII Simpósio da Sociedade Brasileira de Toxinologia, 2002, Pirenópolis. Programa e Resumos, 2002.
SOUZA, B. M. ; MENDES, M. A. ; CESAR, L. M. M. ; SANTOS, L. D. ; MARQUES, M. R. ; KONNO, K. ; PALMA, M. S. . Mass spectrometric characterization of two novel biologically active peptides from the venom of social wasp Polybia paulista. In: VII Simpósio da Sociedade Brasileira de Toxinologia, 2002, Pirenópolis. Programa e Resumos, 2002.
MARQUES, M. R. ; SALLES, H. C. ; MENDES, M. A. ; SOUZA, B. M. ; CESAR, L. M. M. ; KONNO, K. ; TORMESA, C. F. ; RITTER, R. ; PALMA, M. S. . Structural delucidation of tow new b-carbolinetoxins from the droplets of Nephila clavipes web. In: VII Simpósio da Sociedade Brasileira de Toxinologia, 2002, Pirenópolis. Programa e Resumos, 2002.
FUJISHIMA, T. ; KONNO, K. ; NAKAGAWA, K. ; OKANO, T. ; KITTAKA, A. ; KURIHARA, M. ; TAKAYAMA, H. . 2-Methyl analogues of 1a,25-dihydroxyvitamin D3, the potent inducers of cell differentiation and apoptosis: synthesis and biological evaluation. In: 1st Symposium Vitamin D Analogs in Cancer Prevention and Therapy, 2002, Homburg/Saar. Abstracts, 1st Symposium Vitamin D Analogs in Cancer Prevention and Therapy.
KONNO, K. ; ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; J. C. Freitas ; PORTARO, F. C. V. ; PIMENTA, D. C. ; YAMANE, T. . Purification and characterization of peptide toxins from the sea anemone Bundosoma cangicum. In: VII Simpósio da Sociedade Brasileira de Toxinologia, 2002, Pirenópolis. VII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2002. p. 85.
KONNO, K. ; RANGEL, M. ; PROCOPIO, J. ; J. C. Freitas . Ion channel formation by the marine sponge Geodia corticostylifera extract in bilayer membranes. In: VII Simpósio da Sociedade Brasileira de Toxinologia, 2002, Pirenópolis. VII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2002. p. 122.
KONNO, K. ; ALVES, D. S. ; FOSSEY, M. ; RUGGIERO NETO, J. ; AZEVEDO, W. F. ; PALMA, M. S. . Investigations of membrane-peptide interactions for solitary wasp peptide toxins. In: VII Simpósio da Sociedade Brasileira de Toxinologia, 2002, Pirenópolis. VII Simpósio da Sociedade Brasileira de Toxinologia, Programa e Resumos, 2002. p. 202.
KONNO, K. ; ZAHARENKO, A. J. ; OLIVEIRA, J. S. ; J. C. Freitas ; PORTARO, F. C. V. ; PIMENTA, D. C. ; YAMANE, T. . Purification and characterization of peptide toxins from the sea anemone Bundosoma cangicum. In: XVII Simpósio de Biologia Marinha, 2002, São Sebastião. XVII Simpósio de Biologia Marinha, Programa e Resumos, 2002. p. 85.
KONNO, K. ; KITTAKA, A. ; SUHARA, Y. ; FUJISHIMA, T. ; KURIHARA, M. ; TAKAYAMA, H. . The 2α-positive motifs of 1α,25-dihydroxy vitamin D3 in VDR binding. In: 1st Symposium Vitamin D Analogs in Cancer Prevention and Therapy: Anti-cancer Drugs, 2002, Hmoburg. 1st Symposium Vitamin D Analogs in Cancer Prevention and Therapy: Anti-cancer Drugs, 2002. v. 13. p. 27.
KONNO, K. ; SUHARA, Y. ; KITTAKA, A. ; NIHEI, K. ; FUJISHIMA, T. ; TAKAYAMA, H. . Synthesis of 20-epi-2α-substituted 1α,25-dihydroxyvitamin D3 and their VDR binding affinity. In: 1st Symposium Vitamin D Analogs in Cancer Prevention and Therapy: Anti-cancer Drugs, 2002, Homburg. 1st Symposium Vitamin D Analogs in Cancer Prevention and Therapy: Anti-cancer Drugs, 2002. v. 13. p. 43.
KONNO, K. ; KITTAKA, A. ; SUHARA, Y. ; FUJISHIMA, T. ; NIHEI, K. ; NAKAYAMA, H. ; KURIHARA, M. . Modification of 1,25-dihydroxyvitamin D3 at C-20 with C-2 functionalization: Marked increase in affinity for vitamin D receptor and potency of inducing HL-60 cell differentiation. In: 28th Symposium on Progress in Organic Reactions and Synthesis, 2002, Tama/Tokyo. Abstracts of 28th Symposium on Progress in Organic Reactions and Synthesis, 2002. p. 236-237.
PINHEIRO, A. S. ; RUGGIERO NETO, J. ; KONNO, K. ; AZEVEDO JR, W. F. ; ALMEIDA, F. C. L. ; VALENTE, A. P. . Three-dimensional structure determination of a 14-residue peptide toxin from wasp venom by nuclear magnetic resonance. In: XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001, Caxambu. Programa e Resumos,XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001. p. 162.
SOUZA, B. M. ; CESAR, L. M. M. ; KONNO, K. ; PALMA, M. S. . Biochemical characterization of biologically active peptides from the venom of the social wasp Polybia paulista. In: XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001, Caxambu. Programa e Resumos,XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001. p. 201.
MARQUES, M. R. ; KONNO, K. ; PALMA, M. S. . Spider kinin: a novel class of toxin found in Nephila clavipes web. In: XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001, Caxambu. Programa e Resumos, XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001. p. 202.
LORENZI, C. C. B. ; PEREIRA, J. H. ; KONNO, K. ; PALMA, M. S. ; RUGGIERO NETO, J. ; AZEVEDO JR, W. F. . CD analysis and molecular modeling of anoplin, a new class of amphiphilic a-helical peptide from solitary wasp venom. In: XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001, Caxambu. Programa e Resumos, XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001. p. 206.
KONNO, K. ; FONTANA, R. ; CESAR, L. M. M. ; PALMA, M. S. ; HISADA, M. ; NAOKI, H. ; ITAGAKI, Y. ; YASUHARA, T. ; NAKATA, Y. ; NAKAJIMA, T. . Eumenine mastoparans. A new class of amphiphilic a-helical peptides in solitary wasp venoms. In: XXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001, Caxambu. Programa e ResumosXXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBqXXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBqXXX Reunião Anual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2001. p. 206.
NIHEI, K. ; M. J. Kato ; YAMANE, T. ; PALMA, M. S. ; KONNO, K. . A novel and versatile synthesis of acylpolyamine spider toxins. In: 24ª Reunião Anual da Sociedade Brasileira de Química, 2001, Pocos de Caldas. Programa e Resumos, 24ª Reunião Anual da Sociedade Brasileira de Química, 2001. p. PN178.
FUJISHIMA, T. ; KONNO, K. ; NAKAGAWA, K. ; TANAKA, M. ; OKANO, T. ; KURIHARA, M. ; MIYATA, N. ; TAKAYAMA, H. . 2-Methyl substituted analogs of 1a,25-dihydroxyvitamin D3. Synthesis and biological activity of 5,6-trans isomers: analysis of potentiating activity by 2-methyl group. In: 121th Annual Meeting of the Pharmaceutical Society of Japan, 2001, Sapporo. Abstracts of Papers, 121th Annual Meeting of Japan Pharmaceutical Socie, 2001. v. 2. p. 17.
SUHARA, Y. ; NIHEI, K. ; FUJISHIMA, T. ; KITTAKA, A. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological evaluation of 20-epi-2a-substituted analogs of 1a,25-dihydroxyvitamin D3. In: 121th Annual Meeting of the Pharmaceutical Society of Japan, 2001, Sapporo. Abstracts of Papers, 121th Annual Meeting of the Pharmaceutical Society of Japan, 2001. v. 2. p. 17.
SUHARA, Y. ; NIHEI, K. ; FUJISHIMA, T. ; KITTAKA, A. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological evaluation of 20-epi-2a-substituted analogs of 1a,25-dihydroxyvitamin D3. In: 121th Annual Meeting of the Pharmaceutical Society of Japan, 2001, Sapporo. Abstracts of Papers, 121th Annual Meeting of the Pharmaceutical Society of Japan, 2001. v. 2. p. 17.
NIHEI, K. ; M. J. Kato ; YAMANE, T. ; PALMA, M. S. ; KONNO, K. . An efficient and versatile synthesis of acylpolyamine spider toxins. In: 43th Symposium on the Chemistry of Natural Products, 2001, Osaka. Symposium Papers, 43th Symposium on the Chemistry of Natural Products, 2001. p. 515-520.
SUHARA, Y. ; NIHEI, K. ; TANIGAWA, H. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological evaluation of 2a-substituted analogs of 1a,25-dihydroxyvitamin D3. In: 15th Vitamin D Workshop, 2000, Yokohama. Program and Abstracts, 15th Vitamin D Workshop, 2000. p. 36.
FUJISHIMA, T. ; HARADA, Y. ; KONNO, K. ; TAKAYAMA, H. ; NAKAGAWA, K. ; TANAKA, M. ; OKANO, T. ; OZONO, K. . Synthesis and biological activities of 3-methyl substituted analogs of 1a,25-dihydroxyvitamin D3. In: 15th Vitamin D Workshop, 2000, Yokohama. Program and Abstracts,15th Vitamin D Workshop, 2000. p. 38.
KONNO, K. ; PALMA, M. S. ; FONTANA, R. ; YAMANE, T. . Antimicrobial peptides in wasp venom. In: XXXI Reunião Annual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2000, Caxambu. Programa e Resumos, XXXI Reunião Annual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2000. p. 171.
KONNO, K. . Structural and functional diversity of solitary wasp toxins: Novel peptide toxins in solitary wasp venoms. In: VI Sympósio Annual de Sociedade Brasileira de Toxinologia, 2000, São Pedro. Programa e Resumos, VI Sympósio Annual de Sociedade Brasileira de Toxinologia, 2000.
SUHARA, Y. ; NIHEI, K. ; TANIGAWA, H. ; FUJISHIMA, T. ; KONNO, K. ; NAKAGAWA, K. ; OKANO, T. ; TAKAYAMA, H. . Efficient synthesis and biological evaluation of novel 2a-substituted 1a,25-dihydroxyvitamin D3 analogs: remarkable potency for calucium-regulating effect. In: 11th Workshop on Vitamin D, 2000, Nashville. Abstracts, 11th Woprkshop on Vitamin D, 2000. p. 130.
FUJISHIMA, T. ; HARADA, Y. ; KONNO, K. ; NAKAGAWA, K. ; TANAKA, M. ; OKANO, T. ; TAKAYAMA, H. . Efficient synthesis and biological evaluation of 1-methyl-1,25-dihydroxyvitamin D3 and 3-methyl-1,25-dihydroxyvitamin D3. In: 11th Workshop on Vitamin D, 2000, Nashville. Abstracts, 11th Workshop on Vitamin D, 2000. p. 169.
KONNO, K. ; FUJISHIMA, T. ; NAKAGAWA, K. ; TANAKA, M. ; OKANO, T. ; TAKAYAMA, H. . 5,6-Trans-2-methyl-1,25-dihydroxyvitamin D3 and their 20-epimer:Synthesis and biological evaluation. In: 11th Workshop on Vitamin D, 2000, Nashville. Abstracts, 11th Workshop on Vitamin D, 2000. p. 11.
FUJISHIMA, T. ; HARADA, Y. ; KONNO, K. ; TAKAYAMA, H. . Synthesis of 1-methyl- and 3-methyl-1,25-dihydroxvitamin D3. In: 120th Annual Meeting of the Pharmaceutical Society of Japan, 2000, Gifu. Abstracts of Papers, 120th Annual Meeting of the Pharmaceutical Society of Japan, 2000. v. 2. p. 105.
SUHARA, Y. ; NIHEI, K. ; TANIGAWA, H. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of 2a-substituted 1a,25-dihydroxyvitamin D3. In: 120th Annual Meeting of the Pharmaceutical Society of Japan, 2000, Gifu. Abstracts of Papers, 120th Annual Meeting of the Pharmaceutical Society of Japan, 2000. v. 2. p. 140.
KUROBE, M. ; NAKAGAWA, K. ; OKANO, T. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. ; OZONO, K. . Molecular mechanism of action of highly potent vitamin D analogs 2-methyl-1,25-dihydroxyvitamin D3. In: 120th Annual Meeting of the Pharmaceutical Society of Japan, 2000, Gifu. Abstracts of Papers, 120th Annual Meeting of the Pharmaceutical Society of Japan, 2000. v. 3. p. 40.
NAKAGAWA, K. ; KUROBE, M. ; OKANO, T. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Sturcture-specific control of differentiation and apoptosis of cancer cells by 2-methyl-1,25-dihydroxyvitamin D3. In: 120th Annual Meeting of the Pharmaceutical Society of Japan, 2000, Gifu. Abstracts of Papers, 120th Annual Meeting of the Pharmaceutical Society of Japan, 2000. v. 3. p. 40.
FUJISHIMA, T. ; HARADA, Y. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological evaluation of 1-methyl- and 3-methyl-1a,25-dihydroxyvitamin D3. In: 52th Annual Meeting of the Vitamin Society of Japan, 2000. Program and Abstracts, 52th Annual Meeting of the Vitamin Society of Japan, 2000. p. 189.
SUHARA, Y. ; NIHEI, K. ; TANIGAWA, H. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. ; NAKAGAWA, K. ; OKANO, T. . Synthesis and biological evaluation of 2a-subtituted 1a,25-dihydroxyvitamin D3 analogs. In: 52th Annual Meeting of the Vitamin Society of Japan, 2000. Abstracts of Papers, 52th Annual Meeting of the Vitamin Society of Japan, 2000. p. 190.
AZEVEDO, W. F. ; CONDURF, F. ; DELATORRE, P. ; FADEL, V. ; BIAZI, L. C. C. ; PEREIRA, J. H. ; OLIVIERI, J. R. ; LORENZI, C. C. B. ; RUGGIERO NETO, J. ; KONNO, K. . Estudo estrutural de toxinas naturais. In: XXIX Reunião Annual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2000, Caxambu. XXIX Reunião Annual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e ResumosPrograma e Resumos, 2000. p. XL.
W. L. C. Santos ; CANDURI, F. ; DELATORRE, P. ; FADEL, V. ; LORENZI, C. C. B. ; PEREIRA, J. H. ; OLIVIERI, J. R. ; RUGGIERO NETO, J. ; KONNO, K. ; AZEVEDO JR, W. F. . Crystallization of a mastoparan toxin isolatef from solitary wasp Anterhynchium flavomarginatum micado. In: XXIX Reunião Annual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 2000, Caxambu. XXIX Reunião Annual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, Programa e Resumos, 2000. p. 172.
HISADA, M. ; KONNO, K. ; NAOKI, H. ; YASUHARA, T. ; M. A. Juliano ; L. Juliano ; PALMA, M. S. ; NAKAJIMA, T. . Structure of bioactive substances in solitary wasp venom. In: 42th Symposium on the Chemistry of Natural Products, 2000, Naha, Okinawa. 42th Symposium on the Chemistry of Natural Products, Symposium Papers, 2000.
KONNO, K. ; PALMA, M. S. ; FONTANA, R. ; HISADA, M. ; NAOKI, H. ; ITAGAKI, Y. ; YASUHARA, T. ; NAKATA, Y. ; KAWAI, N. ; YAMANE, T. . Novel bioactive peptides isolated from solitary wasp venoms. In: 22th IUPAC Symposium on the Chemistry of Natural Products, 2000, São Carlos. 22th IUPAC Symposium on the Chemistry of Natural Products, Abstracts of Papers, 2000.
NIHEI, K. ; M. J. Kato ; PALMA, M. S. ; YAMANE, T. ; KONNO, K. . A new and versatile synthesis of acylpolyamine spider toxins. In: 22th IUPAC Symposium on the Chemistry of Natural Products, 2000, São Carlos. 22th IUPAC Symposium on the Chemistry of Natural Products, Abstracts of Papers, 2000.
M.-L. Siu-Caldera ; D. S. Rao ; S. Peleg ; A. Weiskopf ; P. Vouros ; KONNO, K. ; FUJISHIMA, T. ; TAKAYAMA, H. ; M. R. Uskokovic ; S. G. Reddy . Metabolism of of 1a,25-dihydroxy-20-epi-vitamin D3 into bioactive intermediary metabolites in rat osterosarcoma (UMR 106) cells. In: 11th Workshop on Vitamin D, 2000, Nashville. Abstracts of 11th Workshop on Vitamin D,, 2000. p. 171.
M.-L. Siu-Caldera ; H. Sekimoto ; TAKAYAMA, H. ; KONNO, K. ; FUJISHIMA, T. ; S. G. Reddy . Metabolism of 2-methyl analogs of 1a,25-dihydroxyvitamin D3 in rat osterosarcoma cells (UMR 106). In: 11th Workshop on Vitamin D, 2000, Nashville. Abstracts of 11th Workshop on Vitamin D, 2000. p. 13.
J. C. Freitas ; RANGEL, M. ; KONNO, K. . Unusual red tide outbreakes caused by planktonic tunicated in Brazil. In: 13th World Congress on Animal, Plant and Microbial Toxins, 2000, Paris. Abstract of 13th World Congress on Animal, Plant and Microbial Toxins, 2000.
OKANO, T. ; NAKAGAWA, K. ; KUROBE, M. ; OZONO, K. ; KONNO, K. ; FUJISHIMA, T. ; TAKAYAMA, H. . Novel 2-methyl-A-ring analogues of 1a,25-dihydroxyvitamin D3 and its 20-epimer that modulate cancer cell differentiation and apoptosis. In: 2000 Meeting of International Society for Preventive Oncology, 2000, Geneva. Abstract of 2000 Meeting of International Society for Preventive Oncology, 2000.
TAKAYAMA, H. ; KONNO, K. ; MAKI, S. ; FUJISHIMA, T. ; LIU, Z. ; HARADA, Y. . Synthesis and biological activities of A-ring modified analogs of 1,25-duhydroxyvitamin D3. In: 14th Vitamin D Workshop, 1999, Yokohama. Program and Abstarcts, 14the Vitamin D Workshop, 1999. p. 10.
NAKAGAWA, K. ; KUROBE, M. ; OKANO, T. ; OZONO, K. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Transctivation of target genes by 2-methyl-20-epi-1a,25-dihydroxyvitaminD3, hybrid analogs modified both in A-ring and the side-chain. In: 14th Vitamin D Workshop, 1999, Yokohama. Program and Abstracts, 14th Vitamin D Workshop, 1999. p. 30.
FUJISHIMA, T. ; LIU, Z. ; KONNO, K. ; TAKAYAMA, H. . 2-Methyl substituted analogs of 1a,25-dihydroxyvitamin D3: Structure-activity relationship of analogs modified both in A-ring and the side-chain. In: 14th Vitamin D Workshop, 1999, Yokohama. Program and Abstracts, 14th Vitamin D Workshop, 1999. p. 34.
KONNO, K. ; FUJISHIMA, T. ; LIU, Z. ; TAKAYAMA, H. . Synthesis and biological activities of 2-methyl substituted analogs of 1a,25-dihydroxyvitamin D3. In: 119th Annual Meeting of the Pharmaceutical Society of Japan, 1999, Tokushima. Abstracts of Papers, 119th Annual Meeting of the Pharmaceutical Society of Japan, 1999. v. 2. p. 98.
IWASAKI, H. ; HOSOTANI, R. ; NAKANO, Y. ; KONNO, K. ; TAKAYAMA, H. . A novel and versatile labeling procedure for 1,25-dihydroxyvitamin D3 derivatives. In: 119th Annual Meeting of the Pharmaceutical Society of Japan, 1999, Tokushima. Abstracts of Papers, 119th Annual Meeting of the Pharmaceutical Society of Japan, 1999. v. 2. p. 184.
KUROBE, M. ; NAKAGAWA, K. ; OKANO, T. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. ; OZONO, K. . Biological activities of hybrid analogs in A-ring and the side-chain of 1a,25-dihydroxyvitamin D3. In: 119th Annual Meeting of the Pharmaceutical Society of Japan, 1999, Tokushima. Abstracts of Papers, 119th Annual Meeting of the Pharmaceutical Society of Japan, 1999. v. 3. p. 72.
NAKAGAWA, K. ; KUROBE, M. ; TANAKA, M. ; OZONO, K. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. ; OKANO, T. . Novel vitamin D analogs regulating differentiation and apoptosis of cancer cells. In: 17th Annual Meeting of the Japanese Society of Bone Metabolism, 1999, Osaka. Absracts of Papers, 17th Annual Meeting of the Japanese Society of Bone Metabolism, 1999. p. 87.
NAKAGAWA, K. ; TANAKA, M. ; OKANO, T. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. ; OZONO, K. . Biological activities of 3-methyl analogs of 1a,25-dihydroxyvitamin D3. In: Kansai Workshop on Calcium, 1999, Osaka. Abstracts, Kansai Workshop on Calcium, 1999.
KONNO, K. ; HISADA, M. ; ITAGAKI, Y. ; NAOKI, H. ; KAWAI, N. ; MIWA, A. ; YASUHARA, T. . Pompilidotoxins (PMTXs), novel peptide neurotoxins in solitary wasp venoms. In: 2nd IUPAC International Conference on Biodiversity, 1999, Belo Horizonte. Programme and Abstracts, 2nd IUPAC International Conference on Biodiversity, 1999. p. 78.
SUHARA, Y. ; NIHEI, K. ; TANIGAWA, H. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of 2-hydroxymethyl analogs of 1a,25-dihydroxyvitamin D3. In: International Conference on Chemistry and Biology of Vitamin D Analogs, 1999, Providence. Abstracts, International Conference on Chemistry and Biology of Vitamin D Analogs, 1999. p. 4.
FUJISHIMA, T. ; HARADA, Y. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological evaluation of all possible A-ring diastereomers of 3-methyl-1,25-dihydroxyvitamin D3. In: International Conference on Chemistry and Biology of Vitamin D Analogs, 1999, Providence. Abstracts, International Conference on Chemistry and Biology of Vitamin D Analogs, 1999. p. 3.
TAKAYAMA, H. ; KONNO, K. ; FUJISHIMA, T. ; MAKI, S. ; LIU, Z. ; MIURA, D. ; CHOKKI, M. ; ISHIZUKA, S. ; SMITH, C. ; DELUCA, H. F. ; NAKAGAWA, K. ; KUROBE, M. ; OKANO, T. . Systematic studies on synthesis, sturctural elucidation, and biological evaluation of A-ring diastereomers of 2-methyl-1a,25-dihydroxyvitamin D3. In: International Conference on Chemistry and Biology of Vitamin D Analogs, 1999, Providence. Abstracts, International Conference on Chemistry and Biology of Vitamin D Analogs, 1999. p. 5.
OKANO, T. ; NAKAGAWA, K. ; KUROBE, M. ; OZONO, K. ; KONNO, K. ; FUJISHIMA, T. ; TAKAYAMA, H. . Structure-specific control of apoptosis by novel 2-methyl-A-ring stereoisomers of 1a,25-dihydorxyvitamin D3 and 20-epi-2-methyl-1a,25-dihydroxyvitamin D3 in HL-60 cells. In: ASBMR 21st Annual Meeting, 1999, St. Louis. Journal of Bone and Mineral Research, 1999. v. 14. p. T474.
KONNO, K. ; SAHARA, Y. ; GOTOH, M. ; MIWA, A. ; TSUBOKAWA, H. ; NAKAYAMA, H. ; ROBINSON, H. ; KAWAI, N. . A novel neurotoxin a-PMTX from wasp venom slows inactivation of sodium current. In: 29th Annual Meeting of American Society for Neuroscience, 1999, Miami. Abstracts of Society of Neuroscience, 1999. v. 25. p. 725.
YOKOTA, H. ; MIYAWAKI, T. ; TSUBOKAWA, H. ; KONNO, K. ; NAKAYAMA, H. ; MASUZAWA, T. ; KAWAI, N. . Efect of a novel wasp toxin b-PMTX on the synapic transmission of hippocampal CA1 pyramidal neurons. In: 29th Annual Meeting of American Society for Neuroscience, 1999, Miami. Abstracts for Society of Neuroscience, 1999. v. 25. p. 725.
AZEVEDO, W. F. ; CONDURF, F. ; FADEL, V. ; OLIVIER, J. R. ; LORENZI, C. C. B. ; KONNO, K. ; PALMA, M. S. ; YAMANE, T. . Structural studies of mastoparan isolated from wasp venom. In: XXVIII Reunião Annual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 1999, Caxambu. Programa e Resumos, XXVIII Reunião Annual, Sociedade Brasileira de Bioquímica e Biologia Molecular-SBBq, 1999. p. 164.
FUJISHIMA, T. ; LIU, Z. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of 2-methyl-20-epi-1a,25-dihydroxyvitamin D3. In: 13th Vitamin D Workshop, 1998, Yokohama. Program and Abstracts, 13th Vitamin D Workshop, 1998. p. 36-37.
MAKI, S. ; HARADA, Y. ; KONNO, K. ; FUJISHIMA, T. ; TAKAYAMA, H. . Synthesis and biological activities of 4-methyl-1a,25-dihydoxyvitamin D3. In: 13th Vitamin D Workshop, 1998, Yokohama. Program and Abstracts, 13th Vitamin D Workshop, 1998. p. 38-39.
KONNO, K. ; FUJISHIMA, T. ; LIU, Z. ; TAKAYAMA, H. . Determination of absolute configuration of 1,3-diols by the modified Mosher's method. In: 74th National Meeting of Chemical Society of Japan, 1998, Kyoto. Book of Abstracts, 74th National Meeting of Chemical Society of Japan, 1998. v. 2. p. 1074.
FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of A-ring diasetereomers of 20-epi-1a,25-dihydroxyvitamin D3. In: 118th Annual Meeting of the Pharmaceutical Society of Japan, 1998, Kyoto. Abstracts of Papers, 118th Annual Meeting of the Pharmaceutical Society of Japan, 1998. v. 2. p. 171.
MAKI, S. ; HARADA, Y. ; LIU, Z. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of 4-methyl-substituted 1a,25-dihydroxyvitamin D3 analogs. In: 118th Annual Meeting of the Pharmacetical Society of Japan, 1998, Kyoto. Abstracts of Papers, 118th Annual Meeting of the Pharmacetical Society of Japan, 1998. v. 2. p. 171.
SUHARA, Y. ; TANIGAWA, H. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of 2a-substituted 1a,25-dihydroxyvitamin D3 analogs. In: 118th Annual Meeting of the Pharmaceutical Society of Japan, 1998, Kyoto. Abstracts of Papers, 118th Annual Meeting of the Pharmaceutical Society of Japan, 1998. v. 2. p. 171.
IWASAKI, H. ; HOSOTANI, R. ; MIYAMOTO, Y. ; NAKANO, Y. ; YAMAMOTO, K. ; YAMADA, S. ; KONNO, K. ; SHINKI, T. ; SUDA, T. ; YAMAGUCHI, K. . Structure determination of a major metabolite of 24,24-difluoro-1a,24-dihydroxyvitamin D3. In: 118th Annual Meeting of the Pharmaceutical Society of Japan, 1998, Kyoto. Abstracts of Papers, 118th Annual Meeting of the Pharmaceutical Society of Japan, 1998. v. 2. p. 171.
KONNO, K. ; TAKAYAMA, H. ; HISADA, M. ; ITAGAKI, Y. ; NAOKI, H. ; MIWA, A. ; KAWAI, N. ; YASUHARA, T. ; NAKATA, Y. . Studies on solitary wasp venoms; Structure of mastoparan-like peptides from eumenid wasp venoms. In: 118th Annual Meeting of the Pharmaceutical Society of Japan, 1998, Kyoto. Abstracts of Papers, 118th Annual Meeting of the Pharmaceutical Society of Japan, 1998. v. 2. p. 160.
HISADA, M. ; ITAGAKI, Y. ; NAOKI, H. ; NAKAJIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Structural analysis of N-terminal blocked peptides from solitary wasp venoms by MALDI-TOF-MS. In: 46th Annual Conference on Mass Spectrometry, 1998, Takasaki. Abstracts, 46th Annual Conference on Mass Spectrometry, 1998. p. 291-292.
KONNO, K. ; MIWA, A. ; TAKAYAMA, H. ; KAWAI, N. . Facilitation of neurotransmission in crustacean neuromuscular synapse by a solitary wasp toxin a-PMTX. In: 21th Annual Meeting of the Japan Neuroscience Society and the 1st Joint-meeting ofthe Japan Neuroscience Society and the Japanese Society for Neurochemistry, 1998, Tokyo. Program and Abstracts, 21th Annual Meeting of the Japan Neuroscience Society and the 1st Joint-meeting ofthe Japan Neuroscience Society and the Japanese Society for Neurochemistry, 1998. p. 174.
YOKOTA, H. ; TSUBOKAWA, H. ; KONNO, K. ; MASUZAWA, N. ; KAWAI, N. . Potentiation of synaptic transmission in hippocampal pyramidal neurons by a novel neurotoxin (a-PMTX) from soitary wasp venom. In: 21th Annual Meeting of the Japan Neuroscience Society and the 1st Joint-meeting of the Japane Neuroscience Society and the Japanese Society for Neurochemistry, 1998, Tokyo. Program and Abstracts, 21th Annual Meeting of the Japan Neuroscience Society and the 1st Joint-meeting of the Japane Neuroscience Society and the Japanese Society for Neurochemistry, 1998. p. 174.
KUROBE, M. ; NAKAGAWA, K. ; OKANO, T. ; FUJISHIMA, T. ; SUHARA, Y. ; KONNO, K. ; TAKAYAMA, H. ; OZONO, K. . Biological activities of 2-methyl-1a,25-dihydroxyvitamin D3. In: 48th Kinki Reagional Meeting of the Pharmaceutical Society of Japan, 1998, Kobe. Abstracts of Papers, 48th Kinki Reagional Meeting of the Pharmaceutical Society of Japan, 1998. p. 119.
NAKAGAWA, K. ; KUROBE, M. ; TSUGAWA, N. ; OKANO, T. ; OZONO, K. ; OHSAWA, A. ; MIKAMI, K. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. ; KUBODERA, N. . Develpopment of vitamin D analogs regulating differentiation and apoptosis of cancer cells. In: 48th Kinki Regional Meeting of the Pharmaceutical Society of Japan, 1998, Kobe. Abstracts of Papers, 48th Kinki Regional Meeting of the Pharmaceutical Society of Japan, 1998. p. 119.
TAKAYAMA, H. ; KONNO, K. ; MAKI, S. ; FUJISHIMA, T. ; LIU, Z. ; HARADA, Y. . Synthesis of 2-methyl- and 4-methyl-1,25-dihydroxyvitamin D3. In: 24th Symposium on Progress in Organic Reactions and Synthesis: Application in the Life Sciences-, 1998, Chiba. Abstracts, 24th Symposium on Progress in Organic Reactions and Synthesis: Application in the Life Sciences-, 1998. p. 152-153.
FUJISHIMA, T. ; LIU, Z. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of 2-methyl substituted 1,25-dihydroxyvitamin D analogs; Structure-activity relationship of analogs modified both in A-ring and sid- chain. In: 18th Symposium on Medicinal Chemistry/7th Annual Meeting of Division of Medicinal Chemistry, 1998, Kyoto. Abstracts, 18th Symposium on Medicinal Chemistry/7th Annual Meeting of Division of Medicinal Chemistry, 1998. p. 167-168.
KONNO, K. . Natural products chemistry of toxins from mushroom and wasp venoms. In: 1st Workshop on Conservation and Sustainable Use of the Plant Diversity from Cerrado and Atlantic Forest: Chemical Diversity and Prospecting for Potential Drugs, 1998, Araraquara. Program, 1st Workshop on Conservation and Sustainable Use of the Plant Diversity from Cerrado and Atlantic Forest: Chemical Diversity and Prospecting for Potential Drugs, 1998.
KONNO, K. ; MAKI, S. ; LIU, Z. ; FUJISHIMA, T. ; MIYASHITA, M. ; SUZUKI, T. ; TAKAYAMA, H. . Synthesis and biological activities of 2-methyl-1a,25-dihydroxyvitamin D3. In: 12th Vitamin D Workshop, 1997, Yokohama. Program and Abstracts of 12th Vitamin D Workshop, 1997. p. 38.
MAKI, S. ; HARADA, Y. ; LIU, Z. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Synthesis of 4-methyl-1a,25-dihydroxyvitamin D3. In: 117th Annual Meeting or the Pharmaceutical Society of Japan, 1997, Machida. Abstracts of Papers, 117th Annual Meeting or the Pharmaceutical Society of Japan, 1997. v. 2. p. 27.
FUJISHIMA, T. ; MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . A novel synthsis of A-ring synthon of 1a,25-dihydroxyvitamin D3. In: 117th Annual Meeting of the Pharmaceutical Society of Japan, 1997, Machida. Abstracts of Papers, 117th Annual Meeting of the Pharmaceutical Society of Japan, 1997. v. 2. p. 27.
KONNO, K. ; TANIGAWA, H. ; TAKAYAMA, H. . Synthesis of polycyclic compounds with a new building block furan-fused sulfolene. In: 117th Annual Meeting of the Pharmaceutical Society of Japan, 1997, Machida. Abstracts of Papers, 117th Annual Meeting of the Pharmaceutical Society of Japan, 1997. v. 2. p. 95.
KONNO, K. ; LIU, Z. ; TAKAYAMA, H. ; ITAGAKI, Y. ; HISADA, M. ; MIWA, A. ; KAWAI, N. . Studies on solitary wasp venoms: Structure of a mastoparan-like peptide from Anterhynchium flavomarginatum micado. In: 117h Annual Meeting of the Pharmaceutical Society of Japan, 1997, Machida. Abstracts of Papers, 117h Annual Meeting of the Pharmaceutical Society of Japan, 1997. v. 2. p. 159.
HISADA, M. ; ITAGAKI, Y. ; NAOKI, H. ; NAKAJIMA, T. ; KONNO, K. ; TAKAYAMA, H. . Structural analysis of peptides in solitary wasp venoms by Ladder Sequencing and CID/MALDI-TOF-MS. In: 45th Annual Conference on Mass Spectrometry, 1997, Nara. Abstracts, 45th Annual Conference on Mass Spectrometry, 1997. p. 158-159.
KONNO, K. ; TAKAYAMA, H. ; HISADA, M. ; ITAGAKI, Y. ; NAOKI, H. ; KAWAI, N. ; MIWA, A. ; YASUHARA, T. . Structure and biological activity of peptides in solitary wasp venoms. In: 39th Symposium on the Chemistry of Natural Products, 1997, Sapporo. Symposium Papers, 39th Symposium on the Chemistry of Natural Products, 1997. p. 229-234.
FUJISHIMA, T. ; LIU, Z. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of 2-methyl-20-epi-1a,25-dihydroxyvitamin D3 analogs. In: 17th Symposium on Medicinal Chemistry/6th Annual Meeting of Division of Medicinal Chemistry, 1997, Tsukuba. Abstracts, 17th Symposium on Medicinal Chemistry/6th Annual Meeting of Division of Medicinal Chemistry, 1997. p. 104-105.
MAKI, S. ; KONNO, K. ; SUZUKI, T. ; TAKAYAMA, H. . Novel oxidation of vitamin D and their related compounds by electrochemical methodology. In: 10th Workshop on Vitamin D, 1997, Strasbourg. Vitamin D, Chemistry, Biology and Clinical Apliations of the Steroid Hormone, 1997. p. 42-43.
KONNO, K. ; MAKI, S. ; LIU, Z. ; SUZUKI, T. ; TAKAYAMA, H. . Synthesis and biological acitivities of 2-methyl-1a,25-dihydroxyvitamin D3. In: 10th Workshop on Vitamin D, 1997, Strasbourg. Vitamin D, Chemistry, Biology and Clinical Applications of the Steroid Hoemone, 1997. p. 73-74.
FUJISHIMA, T. ; LIU, Z. ; KONNO, K. ; TAKAYAMA, H. . Synthesis and biological activities of 2-methyl-20-epi analogues of 1a,25-dihydroxyvitamin D3. In: 10th Workshop on Vitamin D, 1997, Strasbourg. Vitamin D, Chemistry, Biology and Clinical Application of the Steroid Hormone, 1997. p. 75-76.
KONNO, K. ; MAKI, S. ; LIU, Z. ; FUJISHIMA, T. ; TAKAYAMA, H. . Synthesis and biological activities of 2-methyl analogs of 1a,25-dihydroxyvitamin D3. In: 5th Annual Brown University Symposium on Vitamin D, 1997, Providence. Program and Abstracts, 5th Annual Brown University Symposium on Vitamin D, 1997. p. 1.
KONNO, K. ; TAKAYAMA, H. ; HISADA, M. ; ITAGAKI, Y. ; NAOKI, H. ; KAWAI, N. ; MIWA, A. ; YASUHARA, T. ; NAKATA, Y. . Eumenine mastoparans. A new class of mast cell degranulating peptides in the eumenine wasp venom. In: 1st International Peptide Symposium, 1997, Kyoto. Pepide Science-Present and Future, Proceedings of the 1st International Peptide Symposium, 1997. p. 434-435.
MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . Oxidation of allylic alcohols by electrochemical method. Novel rearrangement of prenol under direct anodic oxidation conditions. In: 116th Annual Meeting of the Pharmaceutical Society of Japan, 1996, Kanazawa. Abstracts of Papers, 116th Annual Meeting of the Pharmaceutical Society of Japan, 1996. v. 2. p. 9.
MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . Biomimetic oxidations by elctrochemical method: Oxidation of vitamin D and its derivatives. In: 116th Annual Meeting of the Pharmaceutical Society of Japan, 1996, Kanazawa. Abstracts of Papers, 116th Annual Meeting of the Pharmaceutical Society of Japan, 1996. v. 2. p. 9.
MAKI, S. ; MIYASHITA, M. ; LIU, Z. ; KONNO, K. ; TAKAYAMA, H. . Synthesis of A-ring modified analogs of 1a,25-dihydroxyvitamin D3. In: 116th Annual Meeting of the Pharmaceutical Society of Japan, 1996, Kanazawa. Abstracts of Papers, 116th Annual Meeting of the Pharmaceutical Society of Japan, 1996. v. 2. p. 9.
KONNO, K. ; TAKAYAMA, H. ; HIDOH, O. ; KAWAI, N. . Studies on solitary wasp venoms; Structure of peptides from the venom of Anoplius samariensis. In: 116th Annual Meeting of the Pharmaceutical Society of Japan, 1996, Kanazawa. Abstracts of Papers, 116th Annual Meeting of the Pharmaceutical Society of Japan, 1996. v. 3. p. 89.
MAKI, S. ; LIU, Z. ; HARADA, Y. ; FUJISHIMA, T. ; KONNO, K. ; TAKAYAMA, H. . A convenient and verstile method for synthesis of A-ring modified analogs of 1a,25-dihydroxyvitamin D3. In: 40th Kanto Reasional Meeting of the Pharmaceutical Society of Japan, 1996, Sagamiko. Abstracts of Papers, 40th Kanto Reasional Meeting of the Pharmaceutical Society of Japan, 1996. p. 52.
MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . Biomimetic reactions by electrochemical method: Hydroxylation and olefin cleavage by thallium-porphyrin-cathodic oxidation system. In: 22nd Symposium on Progress in Organic Reactions and Synthesis: Application in the Life Sciences-, 1996, Okayama. Abstracts, 22nd Symposium on Progress in Organic Reactions and Synthesis: Application in the Life Sciences-, 1996. p. 146-150.
KONNO, K. ; MAKI, S. ; LIU, Z. ; FUJISHIMA, T. ; MIYASHITA, M. ; TAKAYAMA, H. . Synthesis and biological activities of 2-methyl substituted analogs of 1a,25-dihydroxyvitamin D3. In: 16th Symposium on Medicinal Chemistry/5th Annual Meeting of Division of Medicinal Chemistry, 1996, Toyama. Abstracts, 16th Symposium on Medicinal Chemistry/5th Annual Meeting of Division of Medicinal Chemistry, 1996. p. 73-74.
MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . Biomimetic oxidation with activated oxygen produced by electrochemical methodology. In: 1996 international Symposium on Organic Reactions-Sendai, 1996, Sendai. Proceedings of 1996 international Symposium on Organic Reactions-Sendai, 1996. p. 166.
KONNO, K. ; MAKI, S. ; SUZUKI, T. ; TAKAYAMA, H. . A novel approach to functionalized polycyclic systems; New aspects of the chemistry of 4H,6H-thieno[3,4-c]furan 5,5-dioxide. In: 17th International Symposium on the Organic Chemistry of Sulfur, 1996, Tsukuba. Abstracts, 17th International Symposium on the Organic Chemistry of Sulfur, 1996. p. 144.
KONNO, K. ; HIDOH, O. ; KAWAI, N. ; MIWA, A. ; TAKAYAMA, H. . Peptide neurotoxins from venom of the spider wasp Anoplius samariensis. In: 20th IUPAC Symposium on the Chemistry of Natural Products, 1996, Chicago. Abstract Publication, 20th IUPAC Symposium on the Chemistry of Natural Products, 1996. p. 37.
KONDO, F. ; MIYASHITA, M. ; KONNO, K. ; TAKAYAMA, H. . A new deprotection procedure for adducts derived from steroidal 5,7-diene and 4-phenyl-1,2,4-triazoline-3,5-dione by DIBAL-H. In: 115th Annual Meeting of the Pharmaceutical Society of Japan, 1995, Sendai. Abstracts of Papers, 115th Annual Meeting of the Pharmaceutical Society of Japan, 1995. v. 2. p. 31.
KONNO, K. ; MAKI, S. ; SAGARA, S. ; TAKAYAMA, H. . Lewis acid promoted rearrangement of cycloadduct of a new building block furan-fused sulfolene. In: 115th Annual Meeting of the Pharmaceutical Society of Japan, 1995, Sendai. Abstracts of Papers, 115th Annual Meeting of the Pharmaceutical Society of Japan, 1995. v. 2. p. 32.
MAKI, S. ; KONNO, K. ; TAKAYAMA, H. . Diels-Alder reaction of a new building block 2-acylated furan-fused sulfolene. In: 115th Annual Meeting of the Pharmaceutical Society of Japan, 1995, Sendai. Abstracts of Papers, 115th Annual Meeting of the Pharmaceutical Society of Japan, 1995. v. 2. p. 66.
YASUHARA, A. ; LIU, Z. ; KONNO, K. ; TAKAYAMA, H. . Synthesis of aromatic ring-fused nucleosides. In: 115th Annual Meeting of the Pharmaceutical Society of Japan, 1995, Sendai. Abstracts of Papers, 115th Annual Meeting of the Pharmaceutical Society of Japan, 1995. v. 2. p. 66.
KONNO, K. ; TAKAYAMA, H. ; MAKI, S. . Biomimetic reactions by an electrochemical method: Oxidation of vitamin D related coumpounds. In: 18th Symposium on Electroorganic Chemistry, 1995, Nagoya. Program and Abstracts, 18th Symposium on Electroorganic Chemistry, 1995. p. 17-18.
KONNO, K. ; MAKI, S. ; TAKAYAMA, H. . A novel approach to functionalized polycyclic systems; Diels-Alder reaction and Lewis acid promoted rearrangement of a new building block 2-acylated furan-fused sulfolene. In: 21st Symposium on Progress in Organic Reactions and Synthesis: Application in the Life Sciences-, 1995, Kyoto. Abstracts, 21st Symposium on Progress in Organic Reactions and Synthesis: Application in the Life Sciences-, 1995. p. 71-75.
KONNO, K. ; MAKI, S. ; KONDO, F. ; IWASAKI, H. ; HOSOTANI, R. ; MIYAMOTO, Y. ; NOGUCHI, Y. ; KASAMA, T. ; SHINKI, T. ; SUDA, T. . Synthesis and biological activities of 24,24-difluorovitamin D3 analogs. In: AFMC International Medicinal Chemistry Symposium (AIMECS 95), 1995, Tokyo. Abstracts, AFMC International Medicinal Chemistry Symposium, 1995. p. 133.
KONNO, K. ; SAGARA, S. ; HAYASHI, T. ; TAKAYAMA, H. . Intermolecular Diels-Alder reaction of cycloadduct of a new building block furan-fused sulfolene. In: 114th Annual Meeting of the Pharmaceutical Society of Japan, 1994, Tokyo. Abstracts of Papers, 114th Annual Meeting of the Pharmaceutical Society of Japan, 1994. v. 2. p. 20.
KONDO, F. ; KONNO, K. ; TAKAYAMA, H. . Synthesis of 24,24-difluoro-1a-hydroxyvitamin D3. In: 114th Annual Meetingg of the Pharmaceutical Society of Japan, 1994, Tokyo. Abstracts of Papers, 114th Annual Meetingg of the Pharmaceutical Society of Japan, 1994. v. 2. p. 90.
KOSHINO, H. ; UZAWA, J. ; YAMANO, K. ; KONNO, K. ; SHIRAHAMA, H. . Structure elucidation of clitidine by pulsed field-gradients 15N HMBC and HMQC. In: 67th National Meeting of the Chemical Society of Japan, 1994, Tokyo. Abstracts of Papers, 67th National Meeting of the Chemical Society of Japan, 1994. p. 125.
IWASAKI, H. ; HOSOTANI, R. ; NOGUCHI, Y. ; KASAMA, T. ; ANDO, K. ; KONNO, K. ; TAKAYAMA, H. . Deuterium labeling at 6,19-positions of 1a-hydroxyvitamin D derivatives. In: 113th Annual Meeting of the Pharmaceutical Society of Japan, 1993, Osaka. Abstracts of Papers, 113th Annual Meeting of the Pharmaceutical Society of Japan, 1993. v. 2. p. 40.
KONNO, K. ; KAWAKAMI, Y. ; HAYASHI, T. ; TAKAYAMA, H. . Regioselective alkylation of a new building block 2-acylated furan-fused sulfolene. In: 113th Annual Meeting of the Pharmaceutical Society of Japan, 1993, Osaka. Abstracts of Papers, 113th Annual Meeting of the Pharmaceutical Society of Japan, 1993. v. 2. p. 136.
HAYASHI, T. ; KAWAKAMI, Y. ; KONNO, K. ; TAKAYAMA, H. . Intramolecular Diels-Alder reaction of a new building block 2-acylated furan-fused sulfolene. In: 113th Annual Meeting of the Pharmaceutical Society of Japan, 1993, Osaka. Abstracts of Papers, 113th Annual Meeting of the Pharmaceutical Society of Japan, 1993. v. 2. p. 136.
KONNO, K. ; HAYASHI, T. ; KAWAKAMI, Y. ; SAGARA, S. ; TAKAYAMA, H. . A novel approach to functionalized polycyclic systems; Intramolecular Diels-Alder reaction and regioselective alkylation of a new building block 2-acylated furan-fused sulfolene. In: 19th Symposium on Progress in Organic Reactions and Synthesis: Application in the Life Sciences-, 1993, Kanazwa. Abstracts, 19th Symposium on Progress in Organic Reactions and Synthesis: Application in the Life Sciences-, 1993. p. 16-20.
KONNO, K. ; OJIMA, K. ; HAYASHI, T. ; TAKAYAMA, H. ; TANABE, M. . Synthesis and biological activity of 1a,25-dihydroxyvitamin D2 analogs bearing amide group in the side chain. In: 112th Annual Meeting of the Pharmaceutical Society of Japan, 1992, Fukuoka. Abstracts of Papers, 112th Annual Meeting of the Pharmaceutical Society of Japan, 1992. v. 2. p. 63.
MANAKA, A. ; HAYASHI, T. ; KONNO, K. ; OJIMA, K. ; TAKAYAMA, H. ; YAMADA, S. ; YAMAGUCHI, K. . Synthesis of 24-F-1a,25-dihydroxyvitamin D2 and its 24-epimer. In: 112th Annual Meeting of the Pharmaceutical Society of Japan, 1992, Fukuoka. 112th Annual Meeting of the Pharmaceutical Society of Japan, 1992. v. 2. p. 64.
IMAE, Y. ; MANAKA, A. ; ABE, E. ; SUDA, T. ; KONNO, K. ; TAKAYAMA, H. ; YAMADA, S. . Biological activity of 24-F-1,25-dihydroxyvitamin D2 and tis 24-epimer. In: 112th Annual Meeting of the Pharmaceutical Sociaety of Japan, 1992, Fukuka. Abstracts of Papers, 112th Annual Meeting of the Pharmaceutical Sociaety of Japan, 1992. v. 2. p. 242.
HASHIMOTO, K. ; KONNO, K. ; HORIKAWA, M. ; SHIRAHAMA, H. . Synthesis and biological acitivity of glutamic acid related compounds (7). In: 61st National Meeting of the Chemical Society of Japan, 1991, Yokohama. Abstracts of Papers, 61st National Meeting of the Chemical Society of Japan, 1991. p. 9.
YAMANO, K. ; KONNO, K. ; SHIRAHAMA, H. . Structure determination of a new amino acid from Clitocybe acromelalga. In: 61st National Meeting of the Chemcial Society of Japan, 1991, Yokohama. Abstracts of Papers, 61st National Meeting of the Chemcial Society of Japan, 1991. p. 3.
KONNO, K. ; OJIMA, K. ; HAYASHI, T. ; TAKAYAMA, H. . A new synthesis of 24,24-difluoro-1a,25-dihydroxyvitamin D3. In: 111th Annual Meeting of the Pharmaceutical Society of Japan, 1991, Tokyo. Abstracts of Papers, 111th Annual Meeting of the Pharmaceutical Society of Japan, 1991. v. 2. p. 45.
OHWADA, S. ; OHUCHI, T. ; HASHIMOTO, K. ; KONNO, K. ; SHIRAHAMA, H. . Synthesis and biological activity of glutamic acid related compounds (5). In: 59th National Meeting of the Chemical Society of Japan, 1990, Yokohama. Abstracts of Papers, 59th National Meeting of the Chemical Society of Japan, 1990. p. 18.
KONNO, K. ; GOODNOW JR, R. ; BUKOWNIK, R. ; KALIMOPOULOS, T. A. ; NAKANISHI, K. ; ELDEFRAWI, A. T. ; ELDEFRAWI, M. E. ; USHERWOOD, P. N. R. ; MANSOUR, N. A. . Structure and synthesis of philanthotoxin, a glutamate receptor antagonist from a wasp venom. In: 32nd Symposium on the Chemsitry of Natural Products, 1989, Nagoya. Symposium Papers, 32nd Symposium on the Chemsitry of Natural Products, 1989.
BULDT, G. ; DENCHER, N. A. ; KONNO, K. ; NAKANISHI, K. ; PLOHN, H. J. ; RAO, B. N. . Heavy-atom labelled retinal localized in the plane of the purple membrane by X-ray diffraction. In: 33rd Annual Meeting of Biophysical Society, 1989. Biophysical Journal, 1989. v. 55. p. 255a.
DENCHER, N. A. ; BULDT, G. ; KONNO, K. ; NAKANISHI, K. ; PLOHN, H. J. ; RAO, B. N. . Localization of the chromophore retinal and of a possible pathway for protons in bacteriophodopsin by diffraction methods. In: Annual Meeting of the German Biochemical Society, 1989. Hoppe-Seyler Biological Chemistry, 1989. v. 370. p. 617.
HIRAYAMA, F. ; KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Toxic principles of Clitocybe acromelalga. In: 56th National Meeting of the Chemical Society of Japan, 1988, Tokyo. Abstracts of Papers, 56th National Meeting of the Chemical Society of Japan, 1988. p. B43.
KOUTALOS, Y. ; EBREY, T. G. ; ODASHIMA, K. ; KONNO, K. ; OK, H. ; SHIMIZU, N. ; DERGUINI, F. ; NAKANISHI, K. . Bleaching and regeneration of octopus rhodopsin in microvillar membranes. In: 32nd Annual Meeting of Biophysical Society, 1988. Biophysical Journal, 1988. v. 53. p. 386a.
SHIRAHAMA, H. ; KONNO, K. ; HASHIMOTO, K. ; MATSUMOTO, T. . Acromelic acids A and B, very potent excitatory amino acids from a poisonous mushroom. In: Neurotox '88: Molecular Basis of Drug and Pesticide Action, 1988, Amsterdam. Neurotox '88: Molecular Basis of Drug and Pesticide Action, 1988. p. 105-122.
EISENSTEIN, L. ; LIN, S. ; NAKANISHI, K. ; ODASHIMA, K. ; KONNO, K. ; DING, W. . FTIR study of carboxylic-acids in the bacteriorhodopsin photocycle. In: 31st Annual Meeting of Biophysical Society, 1987. Biophysical Journal, 1987. v. 51. p. 133a.
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Synthetic studies on acromelic acids, toxic principles of Clitocybe acromelalga-(1) A new pyridine synthesis with the Pummerer reaction. In: 52th National Meeting of the Chemical Society of Japan, 1986, Kyoto. Abstracts of Papers, 52th National Meeting of the Chemical Society of Japan, 1986. v. 2. p. N33.
HASHIMOTO, K. ; KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Synthetic studies on acromelic acids, toxic principles of Clitocybe acromelalga-(2) Synthesis of acromelic acid B. In: 52th National Meeting of the Chemical Society of Japan, 1986, Kyoto. Abstracts of Papers, 52th National Meeting of the Chemical Society of Japan, 1986. v. 2. p. N34.
SHIRAHAMA, H. ; KONNO, K. ; HASHIMOTO, K. ; SHINOZAKI, H. ; ISHIDA, M. ; OKAMOTO, T. ; MATSUMOTO, T. . Synthetic studies on acromelic acids, toxic principles of Clitocybe acromelalga-(3) Synthesis of acromelica acid analogs with potent neuroexcitatory activity. In: 52th National Meeting of the Chemical Society of Japan, 1986, Kyoto. Abstracts of Papers, 52th National Meeting of the Chemical Society of Japan, 1986. v. 2. p. N35.
HIRAYAMA, F. ; HASEGAWA, S. ; KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Antibacterial substances from Russula senesis Imai. In: 1986 Annual Meeting of Japan Society for Bioscience, Biotechnology, and Agrochemistry, 1986, Kyoto. Absracts of Papers, 1986 Annual Meeting of Japan Society for Bioscience, Biotechnology, and Agrochemsitry, 1986. p. 2E-2.
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. ; OHFUNE, Y. . A new approach to synthesis of pyridines and pyridones: Synthesis of acromelic acid A, a toxic principle of Clitocybe acromelalga. In: 17th Congress of Heterocyclic Chemistry, 1985, Sapporo. Book of Astracts, 17th Congress of Heterocyclic Chemistry, 1985. p. 133-136.
KONNO, K. ; HASHIMOTO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. ; OHFUNE, Y. . Studies on toxic principles of Clitocybe acromelalga: Synthesis and biological activity of acromelic acids. In: 28th Symposium on the Chemistry of Natural Products, 1985, Hiroshima. Symposium Papers, 28th Symposium on the Chemistry of Natural Products, 1985. p. 252-258.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Unconventional toxic heterocycles of Clitocybe acromelalga. In: The Nineth International Congress of Heterocyclic Chemistry, 1983, Tokyo. Book of Abstracts, The Nineth International Congress of Heterocyclic Chemisty, 1983.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Studies on toxic principles of Clitocybe acromelalga: Isolation and structure of a new amino acid acromelic acid A. In: 45th National Meeting of the Chemical Society of Japan, 1982, Tokyo. Abstracts of Papers, 45th National Meeting of the Chemical Society of Japan, 1982.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Studies on toxic principles of Clitocybe acromelalga. In: 25th Symposium on the Chemistry of Natural Products, 1982, Tokyo. Symposium Papers, 25th Symposium on The Chemistry of Natural Products, 1982. p. 421-428.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Structure of clithioneine, a new amino acid from Clitocybe acromelalga. In: 43th National Meeting of the Chemical Society of Japan, 1981, Tokyo. Abstracts of Papers, 43th National Meeting of the Chemical Society of Japan, 1981. v. 3. p. F36.
KONNO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Isolation and structure of clitidine, a new pyridine nucleoside from Clitocybe acromelalga. In: 34th National Meeting of the Chemical Society of Japan, 1976, Hiratsuka. Abstracts of Papers, 34th National Meeting of the Chemical Society of Japan, 1976.
TAKAYAMA, H. ; FUJISHIMA, T. ; SUHARA, Y. ; NIHEI, K. ; KONNO, K. . Preparation of vitamin D derivatives having substituents at the 2.alpha.-position 2001 (Patent application).
TAKAYAMA, H. ; FUJISHIMA, T. ; LIU, Z. ; KONNO, K. . Preparation of 2-alkylated vitamin D derivatives 2000 (Patent application).
ITAGAKI, Y. ; KONNO, K. ; KAWAI, N. ; TAKAYAMA, H. . Isolation and preparation of pompilid wasp-derived neuropeptides as glutamate receptor agonists. WO 99 10378, 1999 (Patent application).
TAKAYAMA, H. ; KONNO, K. ; MAKI, S. . Preparation of vitamin D3 derivatives for the treatment of osteoporosis. JP 11 116551, 1999 (Patent application).
KONNO, K. . Bioactive peptides from wasp venoms. Osaka: Workshop of JSPS Future Development Project, 1999 (Lecture at seminar).
KONNO, K. . Solitary wasp toxins-a treasure house of bioactive peptides. São Paulo: Insitituto Butantan, 1999 (Lecture at seminar).
KONNO, K. ; TAKAYAMA, H. ; HIDOH, O. ; KAWAI, N. . Anoplius samariensis neuropeptides as glutamate antagonists. JP 10 72491, 1998 (Patent application).
TAKAYAMA, H. ; KONNO, K. ; FUJISHIMA, T. . Preparation of vitamin D3 derivatives and their pharmaceutical uses. WO 98 50353, 1998 (Patent application).
KONNO, K. . Natural Products Chemistry of toxins from mushroom and wasp venom. São Paulo: Institute of Chemistry, University of São Paulo, 1998 (Lecture at seminar).
KONNO, K. . Natural Products Chemistry of toxins from mushroom and wasp venom. Manaus: INPA, 1998 (Lecture at seminar).
TAKAYAMA, H. ; MAKI, S. ; KONNO, K. . Electrolytic oxidation of organic compounds using hematoporphyrin and metal salts. JP 09 176878, 1997 (Patent application).
TAKAYAMA, H. ; KONNO, K. ; KONDO, F. . Preparation of 24,24-difluoro-1a-hydroxyvitamin D3. JP 08 73425, 1996 (Patent application).
KONNO, K. . Chemistry of solitary wasp toxins. Hirosaki: Faculty of Agriculture and Life Science, Hirosaki University, 1996 (Lecture at seminar).
HAYASHI, T. ; KONNO, K. ; TAKAYAMA, H. . Preparation of vitamin D2 derivatives. JP 06 80689, 1994 (Patent application).
TAKAYAMA, H. ; KONNO, K. ; HAYASHI, T. ; OJIMA, K. ; TANABE, M. . 1a,25-Dihydroxyvitamin D derivatives and their manufacture. JP 06 107625, 1994 (Patent application).
TAKAYAMA, H. ; KONNO, K. ; HAYASHI, T. . Preparation of 24,24-difluoro-5,7-cholestadiene-1a,3b,25-triol. JP 05 59094, 1993 (Patent application).
KONNO, K. . Chemsitry and biology of philanthotoxin, a glutamate antagonist from a solitary wasp venom. Eniwa: Plant Ecochemical Project Seminar, ERATO, JRDC, 1992 (Lecture at seminar).
KONNO, K. . Chemistry of Philanthotoxin, a glutamate antagonist from a solitary wasp venom. Hirakata: Faculty of Pharmaceutical Sciences, Setsunan University, 1991 (Lecture at seminar).
KONNO, K. . Chemistry of natural toxins acting on the glutamate receptors. Basel: Ciba Geigy Ltd., 1989 (Lecture at seminar).
KONNO, K. . Chemistry of mushroom toxins from Clitocybe acromelalga. New York: Department of Chemistry, Columbia University, 1986 (Lecture at seminar).
KONNO, K. ; HAYANO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . 3-Carboxy-1-(D-ribofuranosyl)-1,4-dihydro-4-iminopyridine and its derivatives. JP 77 106875, 1977 (Patent application).

Outras produções

YAMANE, T. ; KERKIS, I. ; KERKIS, A. ; RADIS-BAPTISTA, G. ; HAYASHI, M. A. F. ; KONNO, K. ; SILVA, A. R. B. P. ; PEREIRA, L. V. ; OLIVEIRA, E. B. . Use of crotamine, kit and composition. 2006.

KONNO, K. ; CURY, Y. ; PICOLO, G. . Processo de síntese e composiçãoes farmaceuticas de peptídeos e análogos, derivados do veneno de serpente, por exemplo, do género Crotalus, com atividade analgésica, usos e produtos associados. 2004.

KONNO, K. ; TAKAYAMA, H. ; KAWAI, N. ; ITAGAKI, Y. . Pompilid wasp-derived neuropeptides,. 2003.

KONNO, K. ; TAKAYAMA, H. ; FUJISHIMA, T. . Preparation of vitamin D3 derivatives and their pharmaceutical uses. 2003.

KONNO, K. ; TAKAYAMA, H. ; FUJISHIMA, T. ; SUHARA, Y. ; NIHEI, K. . Vitamin D derivatives having substituents at the 2 alpha-position. 2002.

KONNO, K. ; TAKAYAMA, H. ; FUJISHIMA, T. ; LIU, Z. . 2-Alkylated vitamin D derivatives. 2000.

KONNO, K. ; TAKAYAMA, H. ; MAKI, S. . Vitamin D3 derivative and its production. 1999.

KONNO, K. ; TAKAYAMA, H. ; MAKI, S. . Electrolytically oxidizing methods. 1997.

KONNO, K. ; TAKAYAMA, H. ; KONDO, F. . Fluorinated vitamin D derivatives and its production. 1996.

KONNO, K. ; HAYASHI, T. ; TAKAYAMA, H. . Fluoro derivativeof vitamin D2. 1994.

KONNO, K. ; TAKAYAMA, H. ; HAYASHI, T. ; OJIMA, K. ; TANABE, M. . New 1alpha,25-dihydroxyvitamine D derivative and its production. 1994.

KONNO, K. ; TAKAYAMA, H. ; HAYASHI, T. . Production of provitamine D3 derivatives. 1993.

KONNO, K. ; MATSUMOTO, T. ; SHIRAHAMA, H. . Clithioneine. 1983.

KONNO, K. ; HAYANO, K. ; SHIRAHAMA, H. ; MATSUMOTO, T. . Novel pyridine nucleoside derivatives. 1977.

Histórico profissional

Endereço profissional

University of Toyama. , Sugitani 2630, 9300194 - Toyama, - Japão, Telefone: (8176) 4347605, Fax: (8176) 4345055, URL da Homepage:

Experiência profissional

2008 - Atual

University of Toyama

Vínculo: Servidor Público, Enquadramento Funcional: Associate Professor, Carga horária: 40, Regime: Dedicação exclusiva.

2007 - 2008

Stevens Institute Of Technology

Vínculo: Professor, Enquadramento Funcional: Reseach Associate Professor, Regime: Dedicação exclusiva.

2002 - 2007

Instituto Butantan

Vínculo: Pesquisador, Enquadramento Funcional: Pesquisador, Regime: Dedicação exclusiva.

1998 - 2001

Universidade Estadual Paulista Júlio de Mesquita Filho

Vínculo: Professor Visitante, Enquadramento Funcional: Pesquisador, Carga horária: 40, Regime: Dedicação exclusiva.

Atividades

12/1998 - 06/2001
Pesquisa e desenvolvimento , Instituto de Biociências de Rio Claro, Departamento de Biologia.,Linhas de pesquisa

1989 - 1992

Teikyo University

Vínculo: Bolsista recém-doutor, Enquadramento Funcional: Assistant Professor, Carga horária: 48

Atividades

04/1989 - 03/1992
Pesquisa e desenvolvimento .,Linhas de pesquisa
04/1989 - 03/1992
Ensino,,Disciplinas ministradas, Quimica Organica
04/1989 - 03/1992
Ensino, Quimica Organica e Medicina, Nível: Pós-Graduação,Disciplinas ministradas, Quimica Medicina, Quimica Organica

Propriedade Intelectual

Patentes (3)

Tipo	Título	Data depósito
INVENTOR	Compostos análogos a peptídeos analgésicos derivados de veneno de serpentes crotalus durissus terrificus, seus usos, composições, métodos de preparação e de puruficação	02/05/2005
INVENTOR	Uso de crotamina, kit e composição	18/03/2005
INVENTOR	Processo de sintese e composições farmacêuticas de peptídeos e análogos, derivados do veneno de serpentes por exemplo, do gênero crotalus, com atividade analgésica, usos e produtos associados	06/05/2004