Jean-Paul Bourdineaud

Possui graduação em Química pela l'Ecole Nationale Supérieure de Chimie de Clermont-Ferrand(1986), mestrado em Química pela Universite de Clermont-Ferrand II (FRA)(1986), doutorado em Biologia celular e microbiologia pela Universite D'Aix-Marseille Ii(1989) e pós-doutorado pela Universite de Bordeaux Ii(2000). Atualmente é Professeur da Universite de Bordeaux Ii. Tem experiência na área de Farmacologia, com ênfase em Toxicologia.

Informações coletadas do Lattes em 10/11/2022

Acadêmico

Formação acadêmica

Doutorado em Biologia celular e microbiologia

1986 - 1989

Universite D'Aix-Marseille Ii
Título: In vivo properties of colicin A: channel activity is voltage dependent but translocation may be voltage independent
Orientador: Letellier

Mestrado em Química

1986 - 1986

Universite de Clermont-Ferrand II (FRA)
Orientador: Lazdunski

Pós-doutorado

2000 - 2000

Pós-Doutorado. , Universite de Bordeaux Ii, U.B. II, França.

Áreas de atuação

Grande área: Ciências Biológicas / Área: Farmacologia / Subárea: Toxicologia.

Produções bibliográficas

  • LEREBOURS, A. ; BOURDINEAUD, J. ; VEN, K. ; VANDENBROUCK, T. ; GONZALEZ, P. ; CAMILLERI, V. ; FLORIANI, M. ; GARNIER-LAPLACE, J. ; ADAM-GUILLERMIN, C. . Sublethal effects of waterborne uranium exposures on the zebrafish brain : transcriptional responses and alterations of the olfactory bulb ultrastructure. Environmental Science & Technology , v. 44, p. 1438-1443, 2010.

  • CAMBIER, S. ; GONZALEZ, P. ; DURRIEU, G. ; MAURY-BRACHET, R. ; BOUDOU, A. ; BOURDINEAUD, J. . Serial analysis of gene expression in the skeletal muscles of zebrafish fed with a methylmercury-contaminated diet. Environmental Science & Technology , v. 44, p. 469-475, 2010.

  • CAMBIER, S. ; GONZALEZ, P. ; DURRIEU, G. ; BOURDINEAUD, J. . Cadmium-induced genotoxicity in zebrafish at environmentally relevant doses. Ecotoxicology and Environmental Safety , v. 73, p. 312-319, 2009.

  • LEREBOURS, A. ; GONZALEZ, P. ; ADAM-GUILLERMIN, C. ; CAMILLERI, V. ; BOURDINEAUD, J. ; GARNIER-LAPLACE, J. . Comparative analysis of gene expression in brain, liver, skeletal muscles and gills of the zebrafish (Danio rerio) exposed to environmentally relevant waterborne uranium concentrations. Environmental Toxicology and Chemistry , v. 28, p. 1271-1278, 2009.

  • CAMBIER, S. ; BÉNARD, G. ; MESMER-DUDONS, N. ; GONZALEZ, P. ; ROSSIGNOL, R. ; BRÈTHES, D. ; BOURDINEAUD, J. . At environmental doses, dietary methylmercury inhibits mitochondrial energy metabolism in skeletal muscles of the zebra fish (Danio rerio). International Journal of Biochemistry & Cell Biology , v. 41, p. 791-799, 2009.

  • BOURDINEAUD, J. ; BELLANCE, F. ; BÉNARD, G. ; BRÈTHES, D. ; FUJIMURA, M. ; GONZALEZ, P. ; MARIGHETTO, A. ; MAURY-BRACHET, R. ; MORMÈDE, C. ; PÉDRON, V. ; PHILIPPIN, J. N. ; ROSSIGNOL, R. ; ROSTÈNE, W. ; SAWADA, M. ; LACLAU, M. . Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians.. Environmental Health: A Global Access Science Source , v. 7, p. 53-53, 2008.

  • PIERRON, F. ; BAUDRIMONT, M. ; DUFOUR, S. ; BOSSY, A. ; BALOCHE, S. ; MESMER-DUDONS, N. ; GONZALEZ, P. ; BOURDINEAUD, J. ; MASSABUAU, J. C. . How cadmium could compromise the completion of the European eel's reproductive migration. Environmental Science & Technology , v. 42, p. 4607-4612, 2008.

  • MORREAU, J. L. ; BAUDRIMONT, M. ; CARRIER, P. ; PELTIER, G. ; BOURDINEAUD, J. . Metal binding and antioxidant properties of chimeric tri- and tetra-domained metallothioneins. Biochimie (Paris. Print) , v. 90, p. 705-716, 2008.

  • RIBEIRO, C. A. O. ; MESMER-DUDONS, N. ; GONZALEZ, P. ; DOMINIQUE, Y. ; BOURDINEAUD, J. ; BOUDOU, A. ; MASSABUAU, J. C. . Effects of dietary methylmercury on zebrafish skeletal muscle fibres. Environmental Toxicology and Pharmacology , v. 25, p. 304-309, 2008.

  • ACHARD-JORIS, M. ; MORREAU, J. L. ; LUCAS, M. ; BAUDRIMONT, M. ; MESMER-DUDONS, N. ; GONZALEZ, P. ; BOUDOU, A. ; BOURDINEAUD, J. . Role of metallothioneins in superoxide radical generation during copper redox cycling: defining the fundamental function of metallothioneins. Biochimie (Paris. Print) , v. 89, p. 1474-1488, 2007.

  • PIERRON, F. ; BAUDRIMONT, M. ; GONZALEZ, P. ; BOURDINEAUD, J. ; ELIE, P. ; MASSABUAU, J. C. . Common pattern of gene expression in response to hypoxia or cadmium in the gills of the European glass eel (Anguilla anguilla). Environmental Science & Technology , v. 41, p. 3005-3011, 2007.

  • PIERRON, F. ; BAUDRIMONT, M. ; BOSSY, A. ; BOURDINEAUD, J. ; BRÈTHES, D. ; ELIE, P. ; MASSABUAU, J. C. . Impairment of lipid storage by cadmium in the European eel (Anguilla anguilla). Aquatic Toxicology , v. 81, p. 304-311, 2007.

  • BOURDINEAUD, J. ; BAUDRIMONT, M. ; GONZALEZ, P. ; MORREAU, J. L. . Challenging the model for induction of metallothionein gene expression. Biochimie (Paris. Print) , v. 88, p. 1787-1792, 2006.

  • ACHARD-JORIS, M. ; BOURDINEAUD, J. . Heterologous expression of bacterial and human multidrug resistance proteins protect Escherichia coli against mercury and zinc contamination. BioMetals (Oxford) , v. 19, p. 695-704, 2006.

  • MARIE, V. ; GONZALEZ, P. ; BAUDRIMONT, M. ; BOURDINEAUD, J. ; BOUDOU, A. . Metallothionein response to cadmium and zinc exposures compared in two freshwater bivalves, Dreissena polymorpha and Corbicula fluminea. BioMetals (Oxford) , v. 19, p. 399-407, 2006.

  • ACHARD-JORIS, M. ; GONZALEZ, P. ; MARIE, V. ; BAUDRIMONT, M. ; BOURDINEAUD, J. . Cytochrome c oxydase subunit I gene is up-regulated by cadmium in freshwater and marine bivalves. BioMetals (Oxford) , v. 19, p. 237-244, 2006.

  • GONZALEZ, P. ; BAUDRIMONT, M. ; BOUDOU, A. ; BOURDINEAUD, J. . Comparative effects of direct cadmium contamination on gene expression in gills, liver, skeletal muscles and brain of the zebrafish (Danio rerio). BioMetals (Oxford) , v. 19, p. 225-235, 2006.

  • MOUCHET, F. ; BAUDRIMONT, M. ; GONZALEZ, P. ; CUENOT, Y. ; BOURDINEAUD, J. ; BOUDOU, A. ; GAUTHIER, L. . Genotoxic and stress inductive potential of cadmium in Xenopus laevis larvae. Aquatic Toxicology , v. 78, p. 157-166, 2006.

  • ACHARD-JORIS, M. ; GONZALEZ, P. ; MARIE, V. ; BAUDRIMONT, M. ; BOURDINEAUD, J. . cDNA cloning and gene expression of ribosomal S9 protein gene in the mollusk Corbicula fluminea: a new potential biomarker of metal contamination up-regulated by cadmium and repressed by zinc. Environmental Toxicology and Chemistry , v. 25, p. 527-533, 2006.

  • MARIE, V. ; GONZALEZ, P. ; BAUDRIMONT, M. ; BOUTET, I. ; MORAGA, D. ; BOURDINEAUD, J. ; BOUDOU, A. . Metallothionein gene expression and protein levels in triploid and diploid oysters Crassostrea gigas after exposure to cadmium and zinc. Environmental Toxicology and Chemistry , v. 25, p. 412-418, 2006.

  • BOURDINEAUD, J. . Both arginine and fructose stimulate pH-independent resistance in the wine bacteria Oenococcus oeni. International Journal of Food Microbiology , v. 107, p. 274-280, 2006.

  • TRAN, D. ; BOURDINEAUD, J. ; MASSABUAU, J. C. ; GARNIER-LAPLACE, J. . Modulation of uranium bioaccumulation by hypoxia in the freshwater clam Corbicula fluminea: induction of multixenobiotic resistance protein and heat shock protein 60 in gill tissues. Environmental Toxicology and Chemistry , v. 24, p. 2278-2284, 2005.

  • LEGEAY, A. ; ACHARD-JORIS, M. ; BAUDRIMONT, M. ; MASSABUAU, J. C. ; BOURDINEAUD, J. . Impact of cadmium contamination and oxygenation levels on biochemical responses in the Asiatic clam Corbicula fluminea. Aquatic Toxicology , v. 74, p. 242-253, 2005.

  • GONZALEZ, P. ; DOMINIQUE, Y. ; MASSABUAU, J. C. ; BOUDOU, A. ; BOURDINEAUD, J. . Comparative effects of dietary methylmercury on gene expression in liver, skeletal muscle, and brain of the zebrafish (Danio rerio). Environmental Science & Technology , v. 39, p. 3972-3980, 2005.

  • ACHARD-JORIS, M. ; van den Berg van SAPAROEA, H. B. ; DRIESSEN, A. J. ; BOURDINEAUD, J. . Heterologously expressed bacterial and human multidrug resistance proteins confer cadmium resistance to Escherichia coli. Biochemistry (New York) , v. 44, p. 5916-5922, 2005.

  • ACHARD-JORIS, M. ; BAUDRIMONT, M. ; BOUDOU, A. ; BOURDINEAUD, J. . Induction of a multixenobiotic resistance protein (MXR) in the Asiatic clam Corbicula fluminea after heavy metals exposure. Aquatic Toxicology , v. 67, p. 347-357, 2004.

  • BOURDINEAUD, J. ; NEHME, B. ; TESSE, S. ; LONVAUD-FUNEL, A. . A bacterial gene homologous to ABC transporters protect Oenococcus oeni from ethanol and other stress factors in wine. International Journal of Food Microbiology , v. 92, p. 1-14, 2004.

  • BOURDINEAUD, J. ; NEHME, B. ; TESSE, S. ; LONVAUD-FUNEL, A. . The ftsH gene of the wine bacterium Oenococcus oeni is involved in protection against environmental stress. Applied and Environmental Microbiology (Print) , v. 69, p. 2512-2520, 2003.

  • TONON, T. ; BOURDINEAUD, J. ; LONVAUD-FUNEL, A. . The arcABC gene cluster encoding the arginine deiminase pathway of Oenococcus oeni, and arginine induction of a CRP-like gene. Research in Microbiology (Paris) , v. 152, p. 653-661, 2001.

  • BOURDINEAUD, J. . At acidic pH, the GPA2-cAMP pathway is necessary to counteract the ORD1-mediated repression of the hypoxic SRP1/TIR1 yeast gene. Yeast (Chichester, England. Print) , v. 18, p. 841-848, 2001.

  • BOURDINEAUD, J. ; SAMPAIO, G. ; LAUQUIN, G. J. . A Rox1-independent hypoxic pathway in yeast. Antagonistic action of the repressor Ord1 and activator Yap1 for hypoxic expression of the SRP1/TIR1 gene. Molecular Microbiology , v. 38, p. 879-890, 2000.

  • BOURDINEAUD, J. . At acidic pH, the diminished hypoxic expression of the SRP1/TIR1 yeast gene depends on the GPA2-cAMP and HOG pathways. Research in Microbiology (Paris) , v. 151, p. 43-52, 2000.

  • SAMPAIO, G. ; BOURDINEAUD, J. ; LAUQUIN, G. J. . A constitutive role for GPI anchors in Saccharomyces cerevisiae: cell wall targeting. Molecular Microbiology , v. 34, p. 247-256, 1999.

  • BOURDINEAUD, J. ; van der VAART, J. M. ; DONZEAU, M. ; SAMPAIO, G. ; VERRIPS, C. T. ; LAUQUIN, G. J. . Pmt1 mannosyl transferase is involved in cell wall incorporation of several proteins in Saccharomyces cerevisiae. Molecular Microbiology , v. 27, p. 85-98, 1998.

  • DONZEAU, M. ; BOURDINEAUD, J. ; LAUQUIN, G. J. . Regulation by low temperatures and anaerobiosis of a yeast gene specifying a putative GPI-anchored plasma membrane protein. Molecular Microbiology , v. 20, p. 449-459, 1996.

  • BOURDINEAUD, J. ; BONO, J. J. ; RANJEVA, R. ; CULLIMORE, J. V. . Enzymatic radiolabelling to a high specific activity of legume lipo-oligosaccharidic nodulation factors from Rhizobium meliloti. Biochemical Journal (London. 1984) , v. 306, p. 259-264, 1995.

  • BOURDINEAUD, J. ; HEIERLI, D. ; GAMPER, M. ; VERHOOGT, H. J. ; DRIESSEN, A. J. ; KONINGS, W. N. ; LADUNSKI, C. ; HAAS, D. . Characterization of the arcD arginine:ornithine exchanger of Pseudomonas aeruginosa. Localization in the cytoplasmic membrane and a topological model. Journal of Biological Chemistry (Online) , v. 268, p. 5417-5424, 1993.

  • BOURDINEAUD, J. ; FIEROBE, H. P. ; LADUNSKI, C. ; PAGES, J. M. . Involvement of OmpF during reception and translocation steps of colicin N entry. Molecular Microbiology , v. 4, p. 1737-1743, 1990.

  • BOURDINEAUD, J. ; HOWARD, S. P. ; PAGES, J. M. ; BERNADAC, A. ; LEROY, G. ; BRUSCHI, M. ; LADUNSKI, C. . Cytoplasmic and periplasmic expression of a synthetic gene for ferredoxin in Escherichia coli. Biochimie (Paris. Print) , v. 72, p. 407-415, 1990.

  • BOURDINEAUD, J. ; BOULANGER, P. ; LADUNSKI, C. ; LETELLIER, L. . In vivo properties of colicin A: channel activity is voltage dependent but translocation may be voltage independent. Proceedings of the National Academy of Sciences of the United States of America , v. 87, p. 1037-1041, 1990.

  • BATY, D. ; PATTUS, F. ; PARKER, M. ; BENEDETTI, H. ; FRENETTE, M. ; BOURDINEAUD, J. . Uptake across the cell envelope and insertion into the inner membrane of ion channel-forming colicins in Escherichia coli. Biochimie (Paris. Print) , v. 72, p. 123-130, 1990.

  • BOURDINEAUD, J. ; HOWARD, S. P. ; LADUNSKI, C. . Localization and assembly into the Escherichia coli envelope of a protein required for entry of colicin A. Journal of Bacteriology (Print) , v. 171, p. 2458-2465, 1989.

Histórico profissional

Endereço profissional

  • Universite de Bordeaux I. , Place du Docteur Peyneau, 33120-000 - Franca, SP - Brasil, Telefone: (330) 556223926, Fax: (330) 556549383

Experiência profissional

1994 - Atual

Université de Bordeaux II

Vínculo: Celetista formal, Enquadramento Funcional: Professeur, Carga horária: 40, Regime: Dedicação exclusiva.