Edmond Ekue Creppy

Possui graduação em Farmacy pela University of Dakar(1974) e doutorado em Farmacy pela Université Louis Pasteur(1978). Atualmente é Professor Titular da Université Victor Segalen Bordeaux 2 - Hôpital Pellegrin - Tondu. Tem experiência na área de Farmácia, com ênfase em Análise Toxicológica.

Informações coletadas do Lattes em 10/11/2022

Acadêmico

Formação acadêmica

Doutorado em Farmacy

1975 - 1978

Université Louis Pasteur
Ano de obtenção: 1978;

Graduação em Farmacy

1970 - 1974

University of Dakar

Idiomas

Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Espanhol

Compreende Bem, Fala Razoavelmente, Lê Razoavelmente, Escreve Pouco.

Português

Compreende Razoavelmente, Fala Pouco, Lê Razoavelmente, Escreve Pouco.

Francês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Áreas de atuação

Grande área: Ciências da Saúde / Área: Farmácia / Subárea: Análise Toxicológica.

Grande área: Ciências Biológicas / Área: Genética / Subárea: Genética Molecular e de Microorganismos.

Grande área: Ciências Biológicas / Área: Genética / Subárea: Mutagenese.

Orientou

Adama Traore

Study epigenetic mechanism of okadaic acid in vitro and influence of environmental; 2001; Tese (Doutorado em Farmacy) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Theophile Amando Mobio

Genotoxic and epigenetic effects of Fumonisin B1 in vitro: study of molecular mechanisms and prevention; 2000; Tese (Doutorado em Farmacy) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

François Richeaux

Toxic effects of capsaicin in vivo following transdermal passage and studies of molecular mechanisms in vitro; 2000; Tese (Doutorado em Farmacy) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Karine Abado-Becognee

Fusarium toxins in stored grains, evaluation of global toxicity using a sentinel organism and set up of a bioassay; 1999; Tese (Doutorado em Farmacy) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Abdelhak Belmadani

Mechanism of the neurotoxicity of ochratoxin A, a food contaminant, in the rat: target structures and prevention; 1998; Tese (Doutorado em Farmacy) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Rachid Anane

Evidence for transciutaneous passage of aluminium, bioaccumulation in the brain and neurotoxicity; 1996; Tese (Doutorado em Farmacy) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

William Gerson Matias

Study of molecular mode of action of okadaic acid a diarrhoeic toxin in vivo and in vitro; 1996; Tese (Doutorado em Toxicologie) - Université Bordeaux 2, Conselho Nacional de Desenvolvimento Científico e Tecnológico; Orientador: Edmond Ekue Creppy;

Rachid Ennamany

Molecular mode of action of Bolesatine, glycoprotein from Boletus satanas; 1995; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Isabelle Baudrimont

Variation of the ochratoxin A induced nephrotoxicity following the administration of non metabolic and metabolic substances; 1995; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Milica Murn

Piroxicam and ochratoxin A: prevention of the nephrotoxicity induced by a mycotoxin contaminating foodstuffs and metabolic by an anti inflammatory drug; 1994; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Kleber Chakor

Preventionof subchronic and genotoxic effects of Ochratoxin A a food contaminant in male rat and mouse; 1993; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Victor Kretz

Purification and study of chemical, biological and toxicological properties of Balesatine a glycoprotein from Boletus satanas; 1992; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Charlotte Ralison

Purification, biochemical and toxicological studies of monguine a toxic principle of croton mongue, a Madagascar Euphorbiaceae; 1987; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Amadou Kane

Chronic intoxication by ochratoxin A, a food contaminant: nephrotoxic and genotoxic effects; 1986; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Victor Louis Jeannoda

Chemical, Biochemical and toxicological studies of convulsive principle for plants of the Connaraceae family from Madagascar; 1986; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Rafik Hadidane

Research and identification of mycotoxins in cerals and foodstuffs Tunisia; Correlation with some human diseases; 1985; Tese (Doutorado em Toxicologie) - Université Bordeaux 2,; Orientador: Edmond Ekue Creppy;

Produções bibliográficas

CREPPY, E. E. . Survey of air pollution in Cotonou, Benin-air monitoring and biomarkers. Sci total environmental, 2005.
CREPPY, E. E. . Selective toxicity of a quinoxaline 1,4-di-N-oxide derivative in human tumour cell lines. Arzneimittel Forschung Drug Research , PMID 15819391, v. 55, n.3, p. 177-182, 2005.
CREPPY, E. E. ; AZQUETA,, A ; Pachon, G. . DNA damage induced by quinoxaline 1,4-di-N-oxide derivative in Caco-2 cells evaluated by comet assay. Mutagenesis , v. 20, n.3, p. 165-171, 2005.
CREPPY, E. E. ; Moustaid, K ; Nasser, B. . Comparative evaluation of the toxicity induced by mussels (Mytilus galloprovincialis) from two sites of the Maroccan Atlantic coast in mice. C R Biol, v. 328, n.3, p. 281-290, 2005.
CREPPY, E. E. ; Carvalho Pinto-Silva, C.R. ; Matias, W.G. . Micronucleus test in mussels Perna perna fed with the toxic dinoflagellate Prorocentrum lima. Archives of Toxicology , 2005.
CREPPY, E. E. ; Ouanes Z. ; AyedBoussema, I. ; Bacha, H. . Zearalone induces chromosome aberrations in mouse bone marrow: preventive effect of 17beta-estradiol, progestorone and vitamin E. Mutation Research , v. 565, n.2, p. 139-149, 2005.
CREPPY, E. E. ; Hassen, W. ; El Golli, E. ; Baudrimont, I. ; Mobio, T.A. . Cytotoxicity and Hsp 70 induction in HepG2 cells in response to zearalenone and cytoprotection by sub-lethal heat shock. Toxicology , v. 207, n.2, p. 293-301, 2005.
CREPPY, E. E. ; Chiarappa, P. ; Baudrimont, I. ; Moukha, S. ; Carratu, M.R. . Synergistc effects of fumonisin B1 and ochratoxin A: are in vitro cytotoxicity data predictive of in vivo acute toxicity?. Toxicology , v. 201, n.1, p. 115-123, 2005.
CREPPY, E. E. . Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2.. Toxicology , 2005.
CREPPY, E. E. . Cytotoxicity of Abnormal Savda Munziq aqueous extract in human hepatoma (HepG2) cells.. Fundam. Clin. Pharmacol , v. 4, p. 465-472, 2005.
CREPPY, E. E. ; Hassen, W. ; Bacha, H. . Karyomegaly of tubular kidney cells in human chronic interstitial nephropathy in Tunisia: respective role of Ochratoxin A and possible genetic predisposition. Human & Experimental Toxicology , v. 23, n.7, p. 339-346, 2004.
CREPPY, E. E. ; Hassen, W. ; AZQUETA,, A ; Bacha, H. . Ochratoxin A and beta2-microglobulinuria in health individual and in chronic interstitial nephropathy patients in the centre of Tunisia: a hot spot of ochratoxin a exposure. Toxicology , v. 199, n.2, p. 185-193, 2004.
CREPPY, E. E. ; Ouanes Z. ; Hassen, W. ; Baudrimont, I. ; Bacha, H. . Cytotoxicity, inhibition of DNA and protein synthesis and oxidative damage in culture cells exposed to zearalenone. Toxicology in Vitro : An International Journal Published in Association With BIBRA , v. 18, n.4, p. 467-474, 2004.
CREPPY, E. E. . Ochratoxin A levels in human plasma and foods in Lebanon. Human & Experimental Toxicology , v. 23, n.10, p. 495-501, 2004.
CREPPY, E. E. ; Baudrimont, I. ; Moukha, S. ; Carratu, M.R. . Synergistc effects of fumonisin B1 and ochratoxin A: are in vitro cytotoxicity data predictive of in vivo acute toxicity?. Toxicology , v. 201, n.1, p. 115-123, 2004.
CREPPY, E. E. ; Mobio, T.A. ; Baudrimont, I. ; Carratu, M.R. . Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts.. Toxicology , v. 183, n.1-3, p. 65-75, 2003.
CREPPY, E. E. ; Carvalho Pinto-Silva, C.R. ; Matias, W.G. . Micronucleus induction in mussels exposed to okadaic acid.. Toxicon , v. 41, n.1, p. 93-97, 2003.
CREPPY, E. E. . Magnesium content in seminal fluid as an indicator of chronic prostatitis. Cell Molecular Biology, v. 49, p. 419-423, 2003.
CREPPY, E. E. ; Baudrimont, I. ; Mobio, T.A. ; Bacha, H. . DNA fragmentation, apoptosis and cell cycle arrest induced by zearalenone in cultured DOK, Vero and Caco2 cells: prevention by vitamin E. Toxicology , v. 192, n.2-3, p. 237-248, 2003.
CREPPY, E. E. ; Traore, A. ; Baudrimont, I. . Epigenetic properties of the diarrhetic marine toxin okadaic acid: inhibition of the gap junctional intercellular communication in a human intestine epithelial cell line.. Archives of Toxicology , v. 77, n.11, p. 657-662, 2003.
CREPPY, E. E. ; Ouanes Z. ; Mobio, T.A. ; Bacha, H. . nduction of micronuclei by Zearalenone in Vero monkey kidney cells and in bone marrow cells of mice: protective effect of Vitamin E.. Mutation Research , v. 538, n.1-2, p. 63-70, 2003.
CREPPY, E. E. ; Hassen, W. ; Bacha, H. . Ochratoxin A and human chronic nephropathy in Tunisia: is the situation endemic?. Human & Experimental Toxicology , v. 22, n.2, p. 77-84, 2003.
CREPPY, E. E. ; Traore, A. ; Baudrimont, I. ; Carratu, M.R. . Recent advances in the study of epigenetic effects induced by the phycotoxin okadaic acid.. Toxicology , v. 433, n.9, p. 181-182, 2002.
CREPPY, E. E. . Update of survey, regulation and toxic effects of mycotoxins in Europe.. Toxicology Letters , v. 127, n.1-3, p. 19-28, 2002.
CREPPY, E. E. . Fungal flora and ochratoxin a production in grapes and musts from france.. Fungal flora and ochratoxin a production in grapes and musts from france., v. 50, n.5, p. 1306-1311, 2002.
CREPPY, E. E. ; Baudrimont, I. . Ochratoxin A in human plasma in Morocco: a preliminary survey.. Human & Experimental Toxicology , v. 21, n.5, p. 241-245, 2002.
CREPPY, E. E. ; Traore, A. ; Baudrimont, I. . DNA breaks and cell cycle arrest induced by okadaic acid in Caco-2 cells, a human colonic epithelial cell line.. Archives of Toxicology , v. 75, n.2, p. 110-117, 2001.
CREPPY, E. E. . Lipid peroxidation as pathway of aluminium cytotoxicity in human skin fibroblast cultures: prevention by superoxide dismutase+catalase and vitamins E and C.. Human & Experimental Toxicology , v. 20, n.9, p. 477-481, 2001.
CREPPY, E. E. . Toxicokinetics of ochratoxin A in vervet monkeys (Cercopithecus aethiops).. Archives of Toxicology , v. 75, n.5, p. 262-269, 2001.
CREPPY, E. E. ; Mobio, T.A. ; Baudrimont, I. . Prevention by vitamin E of DNA fragmentation and apoptosis induced by fumonisin B1 in C6 glioma cells.. Archives of Toxicology , v. 74, n.2, p. 112-119, 2000.
CREPPY, E. E. . Distribution of mapacalcine receptors in the central nervous system of rat using the [125I]-labeled mapacalcine derivative.. Brain Research , v. 858, n.1, p. 136-142, 2000.
CREPPY, E. E. ; Traore, A. . Synergistic effects of some metals contaminating mussels on the cytotoxicity of the marine toxin okadaic acid.. Archives of Toxicology , v. 73, n.6, p. 289-295, 1999.
CREPPY, E. E. ; Matias, W.G. ; Traore, A. . Oxygen reactive radicals production in cell culture by okadaic acid and their implication in protein synthesis inhibition.. Human & Experimental Toxicology , v. 18, n.10, p. 634-639, 1999.
CREPPY, E. E. ; AyedBoussema, I. ; Bacha, H. . Foodstuffs and human blood contamination by the mycotoxin ochratoxin A : correlation with chronic interstitial nephropathy in Tunisia. Toxicology , v. 26, p. 552-558, 1995.
CREPPY, E. E. . Detoxification of ochratoxin a food contaminant : Prevention of growth of Aspergillus ochraceus and its production of ochratoxin. Mycotoxin Research, v. 11, p. 37-47, 1995.
CREPPY, E. E. . Human ochratoxicosis in France. Mycotoxins, Endemic Nephropathy and urinary tract tumours.. IARC. SC. Publications, v. 115, p. 145-151, 1991.
CREPPY, E. E. . Evidence for enterohepatic circulation of ochratoxin A in mice. Toxicology , v. 48, p. 293-308, 1988.
CREPPY, E. E. . Epigenetic effects on the phycotoxin okadaic acid. 2003. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Effects of ochratoxin A in the brain of young adults rats. 2002. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Aluminium in the environmental and water. Is there any risk in Africa?. 2001. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Recent advances in epigenetic effects induced by the phycotoxin okadaic acid. 2001. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Update of survey, regulation and toxic effects of mycotoxins in Europe. 2001. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Molecular mechanism in the carcinogenesis of okadaic acid, a marine toxin contaminating mussels. 2000. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Food intoxications. 1999. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Human ochratoxicisis in the world. 1998. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . How aspartame prevents the toxicity of ochratoxin A. 1997. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Trans-cutaneous passage of aluminium and its effects on the brain of young adults rats. 1996. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Ochratoxin A in human blood and chronic interstitial nephropathy: cases report. 1995. (Apresentação de Trabalho/Conferência ou palestra).
CREPPY, E. E. . Prevention of nephrotoxicity and genotoxicity of ochratoxin A, a mycotoxin contaminating foodstuffs. 1995. (Apresentação de Trabalho/Conferência ou palestra).

Outras produções

CREPPY, E. E. . Consultant for the French governement in toxicology and environmental toxicology. 2005.

CREPPY, E. E. . Consultant for the companies Mareva and IDEA in toxicology assays, biocids and in vitro toxicology applied to cosmetics. 2004.

CREPPY, E. E. . Effects of ochratoxin A in the brain of young adults rats. 1996. (Curso de curta duração ministrado/Outra).

Prêmios

2001

Prix of the French National Academy of Medicine, French National Academy of Medicine.

1983

Premier Prix de la Societé Française de Toxicologie, French Society of Toxicology.

1980

Prix de Thèse, University of Strasbourg - France.

Histórico profissional

Endereço profissional

Université Victor Segalen Bordeaux 2 - Hôpital Pellegrin - Tondu. , 146 rue Léo Saignat, Centre, 33076 - Bordeaux, - França, Telefone: (33) 556986606, Fax: (33) 556986685, URL da Homepage:

Experiência profissional

1989 - Atual

Université Victor Segalen Bordeaux 2 - Hôpital Pellegrin - Tondu

Vínculo: Professor, Enquadramento Funcional: Professor Titular, Carga horária: 40, Regime: Dedicação exclusiva.

Atividades

03/1992
Extensão universitária , Department of Toxicology and Applied Hygiene, .,Atividade de extensão realizada, Consultant for the French government in Toxicology and Environmental toxicology.
02/1992
Ensino, Ciências da Saude, Nível: Pós-Graduação,Disciplinas ministradas, Environmental toxicology, Regulatory toxicology, Forensic toxicology, Analytical toxicology, Toxicology of drugs, Molecular, celular and genetic toxicology
02/1989
Direção e administração, .,Cargo ou função, Cargo administrativo.
02/1989
Pesquisa e desenvolvimento , Department of Toxicology and Applied Hygiene, .,Linhas de pesquisa
02/1989
Ensino, Farmacy, Nível: Graduação,Disciplinas ministradas, Environmental Toxicology, Molecular and genetic toxicology, Experimental Toxicology, General Toxicology