Dale Leitman

Possui graduação em Natural Resources pela University Of California Berkeley(1979), graduação em Medicine pela University Of California Davis(1993), mestrado em Biology pela California State University Hayward(1981), doutorado em Physiology pela Stanford University(1987) e pós-doutorado pela University Of California San Francisco(1991). Atualmente é Assistant, Adjunct Professor da University Of California San Francisco.

Informações coletadas do Lattes em 10/11/2022

Acadêmico

Formação acadêmica

Doutorado em Physiology

1981 - 1987

Stanford University
Título: Atrial Natriuretic Factor Receptor Stimulations Of Cyclic GMP
Orientador: Ferid Murad

Mestrado em Biology

1979 - 1981

California State University Hayward
Orientador: L K. Johnson

Graduação em Medicine

1987 - 1993

University of California Davis

Graduação em Natural Resources

1977 - 1979

University Of California Berkeley

Pós-doutorado

1988 - 1991

Pós-Doutorado. , University Of California San Francisco.

Produções bibliográficas

AN, J. ; FOSTER, C. T. ; SCHARSCHMIDT, T. C. ; LOMRI, N. ; LEITMAN, D. . Estrogen receptor b selective transcriptional activity and coregulator recruitment by phytoestrogens. . The Journal of Biological Chemistry , ESTADOS UNIDOS, v. 276, p. 17808-17814, 2001.
MUELLER, M. D. ; MINCHENKO, J. L. V. ; LEBOVIC, D. I. ; LEITMAN, D. . Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and beta. . PNAS. Proceedings of the National Academy of Sciences of the United States of America , ESTADOS UNIDOS, v. 97, p. 10972-10977, 2000.
AN, J. ; RIBEIRO, R. C. J. ; WEBB, P. ; GUSTAFSSON, J. A. ; LOMRI, N. ; KUSHNER, P. J. ; BAXTER, J. D. ; LEITMAN, D. . Estradiol repression of tumor necrosis factor-a transcription requires estrogen receptor function-2 and is enhanced by coactivators.. PNAS. Proceedings of the National Academy of Sciences of the United States of America , ESTADOS UNIDOS, v. 96, p. 15161-15166, 1999.
LEITMAN, D. ; COSTA, C. ; GRAF, H. ; BAXTER, J. D. ; RIBEIRO, R. C. J. . Thyroid Hormone Activation of Transcription is Potentiated by Activators of Cyclic AMP-dependent Protein Kinase. The Journal of Biological Chemistry , ESTADOS UNIDOS, v. 36, p. 21950-21955, 1996.
LEITMAN, D. ; MACKOW, E. R. ; WILLIAMS, T. ; BAXTER, J. D. ; WEST, B. L. . The core promoter of the tumor necrosis factor a gene confers phorbol ester responsiveness to upstream transcriptional activators. Molecular and Cellular Biochemistry , ESTADOS UNIDOS, v. 12, p. 1352-1356, 1992.
LEITMAN, D. ; RIBEIRO, R. C. J. ; MACKOW, E. R. ; BAXTER, J. D. ; WEST, B. L. . Identification of a tumor necrosis factor responsive element in the tumor necrosis factor a gene. The Journal of Biological Chemistry , ESTADOS UNIDOS, v. 266, p. 9343-9346, 1991.
SCHRODER, H. ; BARANN, M. ; BENNETT, B. M. ; LEITMAN, D. . Cross-tolerance to L-arginine-dependent guanylate cyclase activators in nitrate-tolerance LLC-PK1 kidney epithelial cells. Pol J Pharmacol Pharm, Estados Unidos, v. 42, p. 259-263, 1990.
BENNETT, B. M. ; LEITMAN, D. ; SCHRODER, H. ; KAWAMOTO, J. H. ; NAKATSU, K. ; MURAD, F. . Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines.. Journal of Pharmacology and Experimental Therapeutics , Estados Unidos, v. 250, p. 316-323, 1989.
WALDMAN, S. A. ; RAPOPORT, R. M. ; FISCUS, R. R. ; LEITMAN, D. ; CHANG, L. Y. ; MURAD, F. . Regulation of particulate guanylate cyclase by atriopeptins: Relation between peptide structure, receptor binding and enzyme kinetics. . Biochimica and Biophysica Acta, ESTADOS UNIDOS, v. 992, p. 157-162, 1989.
WALDMAN, S. A. ; LEITMAN, D. ; CHANG, L. Y. ; MURAD, F. . Comparison of particulate guanylate cyclase in cells with and without atrial natriuretic peptide receptor binding activity. Molecular and Cellular Biochemistry , Estados Unidos, v. 90, p. 19-25, 1989.
LEITMAN, D. ; ANDRESEN, J. W. ; CATALANO, R. M. ; WALDMAN, S. A. ; TUAN, J. J. ; MURAD, F. . Atrial natriuretic peptide binding, cross-linking and stimulation of cyclic GMP accumulation and particulate guanylate cyclase activity in cultured cells. The Journal of Biological Chemistry , Estados Unidos, v. 263, p. 3720-3728, 1988.
LEITMAN, D. ; AGNOST, V. L. ; CATALANO, R. M. ; SCHRODER, H. ; WALDMAN, S. A. ; BENNETT, B. M. ; TUAN, J. J. ; MURAD, F. . Atrial natriuretic peptide, oxytocin and vasopressin increase cyclic GMP in LLC-PK1 kidney epithelial cells. Endocrinology (Philadelphia) , ESTADOS UNIDOS, v. 122, p. 1478-1485, 1988.
SCHRODER, H. ; LEITMAN, D. ; BENNETT, B. M. ; WALDMAN, S. A. ; MURAD, F. . Glyceryl trinitrate induced-desensitization of guanylate cyclase in cultured rat lung fibroblasts. . Journal of Pharmacology and Experimental Therapeutics , Estados Unidos, v. 245, p. 413-418, 1988.
LEITMAN, D. ; AGNOST, V. L. ; ANDRESEN, J. W. ; MURAD, F. . Atrial natriuretic factor and sodium nitroprusside increase cyclic GMP in cultured rat lung fibroblasts by activating different forms of guanylate cyclase. . Biochemical Journal (London) , Estados Unidos, v. 244, p. 66-71, 1987.
SCHODER, H. ; LEITMAN, D. ; BENNETT, B. M. ; HAYWARD, L. D. ; MURAD, F. . Cultured rat lung fibroblasts as a model for organic nitrate-induced cyclic GMP accumulation and activation of guanylate cyclase. . Journal Of Applied Cardiology, Estados Unidos, v. 2, p. 310-311, 1987.
MURAD, F. ; WALDMAN, S. A. ; MOLINA, C. ; BENNETT, B. M. ; LEITMAN, D. . Regulation and role of guanylate cyclase-cyclic GMP in vascular relaxation. Progress In Clinical And Biological Research, Estados Unidos, v. 249, p. 65-76, 1987.
LEITMAN, D. ; FISCUS, R. R. ; MURAD, F. ; FORSKOLIN, F. . Phosphodiesterase inhibitors and cyclic AMP analogs inhibit proliferation of cultured bovine aortic endothelial cells. Journal of Cellular Physiology , Estados Unidos, v. 127, p. 237-243, 1986.
LEITMAN, D. ; MURAD, F. . Comparison of binding and cyclic GMP accumulation by atrial natriuretic peptides in endothelial cells. Journal of Cellular Physiology , Estados Unidos, v. 885, p. 74-79, 1986.
KUNO, T. ; ANDRESEN, J. W. ; KAMISAKI, Y. ; WALDMAN, S. A. ; CHANG, L. ; SAHEKI, S. ; LEITMAN, D. ; NAKANE, M. ; MURAD, F. . Co-purification of an atrial natriuretic factor receptor and particulate guanylate cyclase from rat lung. . The Journal of Biological Chemistry , Estados Unidos, v. 261, p. 5817-5823, 1986.
LEITMAN, D. ; ANDRESEN, J. W. ; KUNO, T. ; KAMISAKI, Y. ; CHANG, J. K. ; MURAD, F. . Identification of multiple binding sites for atrial natriuretic factor by affinity cross-linking in cultured endothelial cells. The Journal of Biological Chemistry , Estados Unidos, v. 261, p. 11155-11160, 1986.
LEITMAN, D. ; ANDRESEN, J. W. ; KUNO, T. ; KAMISAKI, Y. ; CHANG, J. K. ; MURAD, F. . Identification of two binding sites for atrial natriuretic factor in endothelial cells: Evidence for a receptor subtype coupled to guanylate cyclase. . Transactions Of The American Association Of Physicians, Estados Unidos, v. 99, p. 103-113, 1986.
LEITMAN, D. ; WALDMAN, S. A. ; RAPOPORT, R. M. ; MURAD, F. . Specific atrial natriuretic factor receptors mediate increased cyclic GMP accumulation in cultured bovine aortic endothelial and smooth muscle cells. Transctions The American Association Of Physicians, Estados Unidos, v. 98, p. 243-252, 1985.
LEITMAN, D. ; CHANG, C. H. ; KOHSE, K. P. ; HIRATA, M. ; SONG, D. L. ; WALDMAN, S. A. . Signal transduction pathways of atrial natriuretic peptide receptor subtypes. In: Dale Leitman. (Org.). Atrial and Brain Natriuretic Peptides. : , 1991, v. , p. 149-164.
LEITMAN, D. ; MOLINA, C. ; WALDMAN, S. A. ; MURAD, F. . Atrial natriuretic peptide receptors and the guanylate cyclase-cyclic GMP system. In: Dale Leitman. (Org.). Biological and molecular aspects of atrial factors. : , 1988, v. , p. 36-59.

Prêmios

1999

Paul Beeson Physician Faculty Scholar, .

1988

Endocrinology NIH Training Grant, .

1988

Paul Beeson Physician Faculty Scholar, .

Histórico profissional

Endereço profissional

University Of California San Francisco. , 513 Parnassus Ave.Rm. HSE 1320, CA 94122 - San Francisco, - Estados Unidos, URL da Homepage:

Experiência profissional

1998 - 1999

University Of California San Francisco

Vínculo: Clinical Instructor, Enquadramento Funcional: Clinical Instructor, Regime: Dedicação exclusiva.

Atividades

06/1998
Pesquisa e desenvolvimento .,Linhas de pesquisa