Michelina Iacovino

Possui graduação em science and food technology pela Università degli Studi del Molise(1999), doutorado em Applied Biochemistry and Chemistry pela Università degli Studi del Molise(2004), pós-doutorado pela University of Minnesota(2010) e pós-doutorado pela UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER(2008). Atualmente é Assistant Professor da University of Minnesota e Revisor de periódico da Stem Cells and Development. Tem experiência na área de Biologia Geral, com ênfase em Stem Cell Biology. Atuando principalmente nos seguintes temas:Mitochondrial DNA inheritance.

Informações coletadas do Lattes em 10/11/2022

Acadêmico

Formação acadêmica

Doutorado em Applied Biochemistry and Chemistry

2000 - 2004

Universita degli studi del Molise
Título: mtDNA inheritance in Saccharomyces cerevisiae: mutants ilv5p, Tim17p and Oxa1p involment
Orientador: Salvatore Passarella, Ronald Butow
com Bolsista do(a): Universita degli studi del Molise. Palavras-chave: Mitochondrial DNA inheritance.Grande área: Ciências Biológicas / Área: Biologia Geral. Grande Área: Ciências Biológicas / Área: Biologia Geral / Subárea: yeast biology.

Graduação em science and food technology

1994 - 1999

Universita degli studi del Molise
Orientador: Salvatore Passarella

Pós-doutorado

2008 - 2010

Pós-Doutorado. , University of Minnesota, UMN, Estados Unidos. , Grande área: Ciências Biológicas / Área: Biologia Geral / Subárea: Stem Cell Biology.

2004 - 2008

Pós-Doutorado. , UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER. , Bolsista do(a): National Institute of health. , Grande área: Ciências Biológicas / Área: Biologia Geral. , Grande Área: Ciências Biológicas / Área: Biologia Geral / Subárea: Stem Cell Biology.

Idiomas

Bandeira representando o idioma Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Bandeira representando o idioma Português

Compreende Razoavelmente, Fala Razoavelmente, Lê Razoavelmente, Escreve Pouco.

Bandeira representando o idioma Italiano

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Bandeira representando o idioma Francês

Compreende Razoavelmente, Fala Pouco, Lê Razoavelmente, Escreve Razoavelmente.

Áreas de atuação

Grande área: Ciências Biológicas / Área: Biologia Geral / Subárea: Stem Cell Biology.

Produções bibliográficas

  • Mazzoni, Esteban O ; Mahony, Shaun ; IACOVINO, M. ; Morrison, Carolyn A ; Mountoufaris, George ; Closser, Michael ; Whyte, Warren A ; Young, Richard A ; Kyba, Michael ; Gifford, David K ; Wichterle, Hynek . Embryonic stem cell based mapping of developmental transcriptional programs. Nature Methods , v. online, p. online, 2011.

  • Iacovino, Michelina ; Bosnakovski, Darko ; Fey, Holger ; Rux, Danielle ; Bajwa, Gagan ; Mahen, Elisabeth ; Mitanoska, Ana ; Xu, Zhaohui ; Kyba, Michael . Inducible Cassette Exchange: A Rapid and Efficient System Enabling Conditional Gene Expression in Embryonic Stem and Primary Cells. Stem Cells (Dayton, Ohio) , v. 29, p. 1580-1588, 2011.

  • Liebau, Stefan ; Tischendorf, Michael ; Ansorge, Daniel ; Linta, Leonhard ; Stockmann, Marianne ; Weidgang, Clair ; Iacovino, Michelina ; Boeckers, Tobias ; von Wichert, Götz ; Kyba, Michael ; Kleger, Alexander . An Inducible Expression System of the Calcium-Activated Potassium Channel 4 to Study the Differential Impact on Embryonic Stem Cells. Stem Cells International , v. 2011, p. 1-12, 2011.

  • Zhu, Rui ; Iacovino, Michelina ; Mahen, Elisabeth ; Kyba, Michael ; Matin, Angabin . Transcripts that associate with the RNA binding protein, DEAD-END (DND1), in embryonic stem (ES) cells. BMC Molecular Biology , v. 12, p. 37, 2011.

  • Chalamalasetty, Ravindra B. ; Dunty, William C. ; Biris, Kristin K. ; Ajima, Rieko ; Iacovino, Michelina ; Beisaw, Arica ; Feigenbaum, Lionel ; Chapman, Deborah L. ; Yoon, Jeong Kyo ; Kyba, Michael ; Yamaguchi, Terry P. . The Wnt3a/ -catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program. NAT COMMUN , v. 2, p. 390, 2011.

  • Caprioli, A. ; Koyano-Nakagawa, N. ; IACOVINO, M. ; Shi, X. ; Ferdous, A. ; Harvey, R. P. ; Olson, E. N. ; Kyba, M. ; Garry, D. J. . Nkx2-5 Represses Gata1 Gene Expression and Modulates the Cellular Fate of Cardiac Progenitors During Embryogenesis. Circulation (New York, N.Y.) , v. 123, p. 1633-1641, 2011.

  • Chen, Chialin ; Chai, Jing ; Singh, Lipi ; Kuo, Ching-Ying ; Jin, Liang ; Feng, Tao ; Marzano, Scott ; Galeni, Sheetal ; Zhang, Nan ; Iacovino, Michelina ; Qin, Lihui ; Hara, Manami ; Stein, Roland ; Bromberg, Jonathan S. ; Kyba, Michael ; Ku, Hsun Teresa . Characterization of an Differentiation Assay for Pancreatic-Like Cell Development from Murine Embryonic Stem Cells: Detailed Gene Expression Analysis. Assay and Drug Development Technologies , v. 9, p. 403-419, 2011.

  • Iacovino, Michelina ; Chong, Diana ; Szatmari, Istvan ; Hartweck, Lynn ; Rux, Danielle ; Caprioli, Arianna ; Cleaver, Ondine ; Kyba, Michael . HoxA3 is an apical regulator of haemogenic endothelium. Nature Cell Biology , v. 13, p. 72-78, 2010.

  • Mallanna, Sunil K. ; Ormsbee, Briana D. ; Iacovino, Michelina ; Gilmore, Joshua M. ; Cox, Jesse L. ; Kyba, Michael ; Washburn, Michael P. ; Rizzino, Angie . Proteomic Analysis of Sox2-Associated Proteins During Early Stages of Mouse Embryonic Stem Cell Differentiation Identifies Sox21 as a Novel Regulator of Stem Cell Fate. Stem Cells (Dayton, Ohio) , v. 28, p. 1715-1727, 2010.

  • Szatmari, Istvan ; Iacovino, Michelina ; Kyba, Michael . The Retinoid Signaling Pathway Inhibits Hematopoiesis and Uncouples from the Hox Genes During Hematopoietic Development. Stem Cells (Dayton, Ohio) , v. 28, p. 1518-1529, 2010.

  • Zhao, L. ; Dong, H. ; Zhang, C. C. ; Kinch, L. ; Osawa, M. ; IACOVINO, M. ; Grishin, N. V. ; Kyba, M. ; Huang, L. J.-s. . A JAK2 Interdomain Linker Relays Epo Receptor Engagement Signals to Kinase Activation. The Journal of Biological Chemistry (Print) , v. 284, p. 26988-26998, 2009.

  • Ferdous, A. ; Caprioli, A. ; IACOVINO, M. ; Martin, C. M. ; Morris, J. ; Richardson, J. A. ; Latif, S. ; Hammer, R. E. ; Harvey, R. P. ; Olson, E. N. ; Kyba, M. ; Garry, D. J. . Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo. Proceedings of the National Academy of Sciences of the United States of America , v. 106, p. 814-819, 2009.

  • Iacovino, Michelina ; Hernandez, Carmen ; Xu, Zhaohui ; Bajwa, Gagan ; Prather, Melissa ; Kyba, Michael . A Conserved Role for Hox Paralog Group 4 in Regulation of Hematopoietic Progenitors. Stem Cells and Development , v. 18, p. 783-792, 2009.

  • IACOVINO, M. ; Granycome, C. ; Sembongi, H. ; Bokori-Brown, M. ; Butow, R. A. ; Holt, I. J. ; Bateman, J. M. . The conserved translocase Tim17 prevents mitochondrial DNA loss. Human Molecular Genetics (Print) , v. 18, p. 65-74, 2008.

  • Bondue, Antoine ; Lapouge, Gaëlle ; Paulissen, Catherine ; Semeraro, Claudio ; Iacovino, Michelina ; Kyba, Michael ; Blanpain, Cédric . Mesp1 Acts as a Master Regulator of Multipotent Cardiovascular Progenitor Specification. Cell Stem Cell , v. 3, p. 69-84, 2008.

  • Pallotta, Maria Luigia ; Valenti, Daniela ; Iacovino, Michelina ; Passarella, Salvatore . Two separate pathways for d-lactate oxidation by Saccharomyces cerevisiae mitochondria which differ in energy production and carrier involvement. Biochimica et Biophysica Acta. Bioenergetics , v. 1608, p. 104-113, 2004.

  • Bateman, J. M. ; Iacovino, Michelina . Mitochondrial DNA Instability Mutants of the Bifunctional Protein Ilv5p Have Altered Organization in Mitochondria and Are Targeted for Degradation by Hsp78 and the Pim1p Protease. The Journal of Biological Chemistry (Print) , v. 277, p. 47946-47953, 2002.

Prêmios

2010

2010 "Stem Cell Differentiation and Dedifferentiation" Keystone Symposia Conference Travel Award, Keystone Symposia Conference.

2010

2010 Lillehei Scholar Award. University of Minnesota, Cardiovascular Division and The Lillehei Heart Institute., LHI scholar award.

Histórico profissional

Endereço profissional

  • University of Minnesota, Lillehei Heart Institute. , 312 Church St SE, 55455 - Minneapolis, - Estados Unidos, Telefone: () 6126252173

Experiência profissional

2010 - Atual

University of Minnesota

Vínculo: Empregado, Enquadramento Funcional: Assistant Professor

Atividades

  • 11/2010

    Pesquisa e desenvolvimento , Lillehei Heart Institute, .,Linhas de pesquisa