Arturo Casadevall
Arturo Casadevall is Leo and Julia Forchheimer Professor of Microbiology & Immunology at the Albert Einstein College of Medicine of Yeshiva University. He is Chairman of the Department of Microbiology and Immunology, and served as Director of the Division of Infectious Diseases from 2000-2006. Dr Casadevall received both his M.D. and Ph.D. (Biochemistry) degrees from New York University (NYU) in New York, New York. Subsequently, he completed internship and residency in internal medicine at Bellevue Hospital in New York. Later he completed subspecialty training in Infectious Diseases at the Montefiore Medical Center and Albert Einstein College of Medicine. Dr. Casadevall s major research interests are in fungal pathogenesis and the mechanism of antibody action. In the area of Biodefense, he has an active research program to understand the mechanisms of antibody-mediated neutralization of Bacillus anthracis toxins. He is a fellow of the American Academy of Microbiology and was elected to the American Society for Clinical Investigation, to the American Association of Physicians and as a fellow of the AAAS. Dr. Casadevall has served on numerous advisory committees to the NIH including study sections, strategic planning for the NIAID and the blue ribbon panel on response to bioterrorism. He currently co-chairs the Board of Scientific Counselors for the NIAID and is a member of the National Science Advisory Board for Biosecurity (NSABB). He is the founding editor of the first ASM general journal, mBio and serves on the editorial boards of several journals.
Informações coletadas do Lattes em 10/11/2022
Acadêmico
Formação acadêmica
Doutorado em Biochemistry
1979 - 1984
New York University
Título: DNA Structures in Philamentous Virus Systems
Orientador: L. A. Day
Bolsista do(a): National Institutes of Health.
Pós-doutorado
1989 - 1992
Pós-Doutorado. , Albert Einstein College of Medicine, Einstein, Estados Unidos. , Bolsista do(a): National Institutes of Health.
Áreas de atuação
Grande área: Ciências Biológicas / Área: Microbiologia.
Grande área: Ciências Biológicas / Área: Imunologia.
Grande área: Ciências Biológicas / Área: Bioquímica.
Grande área: Ciências da Saúde / Área: Medicina / Subárea: Clínica Médica/Especialidade: Doenças Infecciosas e Parasitárias.
Produções bibliográficas
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BROWN, LISA ; KESSLER, ANNE ; CABEZAS-SANCHEZ, PABLO ; LUQUE-GARCIA, JOSE L. ; Casadevall, Arturo . Extracellular vesicles produced by the Gram-positive bacterium are disrupted by the lipopeptide surfactin. Molecular Microbiology (Print) , v. 1, p. n/a-n/a, 2014.
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PARK, YOON-DONG ; SHIN, SOOWAN ; PANEPINTO, JOHN ; RAMOS, JEANIE ; QIU, JIN ; Frases, Susana ; ALBUQUERQUE, PATRICIA ; Cordero, Radames J. B. ; ZHANG, NANNAN ; HIMMELREICH, UWE ; BEENHOUWER, DAVID ; BENNETT, JOHN E. ; Casadevall, Arturo ; WILLIAMSON, PETER R. . A Role for LHC1 in Higher Order Structure and Complement Binding of the Cryptococcus neoformans Capsule. PLoS Pathogens (Online) , v. 10, p. e1004037, 2014.
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OLAYA-ABRIL, ALFONSO ; Prados-Rosales, Rafael ; MCCONNELL, MICHAEL J. ; MARTÍN-PEÑA, REYES ; GONZÁLEZ-REYES, JOSÉ ANTONIO ; JIMÉNEZ-MUNGUÍA, IRENE ; GÓMEZ-GASCÓN, LIDIA ; FERNÁNDEZ, JAVIER ; LUQUE-GARCÍA, JOSÉ L. ; GARCÍA-LIDÓN, CARLOS ; ESTÉVEZ, HÉCTOR ; PACHÓN, JERÓNIMO ; OBANDO, IGNACIO ; Casadevall, Arturo ; Pirofski, Liise-anne ; RODRÍGUEZ-ORTEGA, MANUEL J. . Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae. Journal of Proteomics (Print) , v. 106, p. 46-60, 2014.
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CHASKES, STUART ; CAMMER, MICHAEL ; NIEVES, EDWARD ; Casadevall, Arturo . Pigment Production on L-Tryptophan Medium by Cryptococcus gattii and Cryptococcus neoformans. Plos One , v. 9, p. e91901, 2014.
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CASADEVALL, A. ; FANG, F. C. . Causes for the Persistence of Impact Factor Mania. mBio (Online) , v. 5, p. e00064-14-e00064-14, 2014.
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STUKES, S. A. ; COHEN, H. W. ; CASADEVALL, A. . Temporal Kinetics and Quantitative Analysis of Cryptococcus neoformans Nonlytic Exocytosis. Infection and Immunity (Print) , v. 82, p. 2059-2067, 2014.
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SILVA, B. M. A. ; PRADOS-ROSALES, R. ; ESPADAS-MORENO, J. ; WOLF, J. M. ; LUQUE-GARCIA, J. L. ; GONCALVES, T. ; CASADEVALL, A. . Characterization of Alternaria infectoria extracellular vesicles. Medical Mycology (Oxford. Print) , v. 52, p. 202-210, 2014.
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ALBUQUERQUE, PRISCILA C ; FONSECA, FERNANDA L ; DUTRA, FABIANNO F ; BOZZA, MARCELO T ; Frases, Susana ; Casadevall, Arturo ; Rodrigues, Marcio L . Cryptococcus neoformans glucuronoxylomannan fractions of different molecular masses are functionally distinct. Future Microbiology (Print) , v. 9, p. 147-161, 2014.
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RIVERA, J. ; SELLERS, R. S. ; ZENG, W. ; VAN ROOIJEN, N. ; CASADEVALL, A. ; GOLDMAN, D. L. . Platelet Activating Factor contributes to Bacillus anthracis lethal toxin-associated damage. The Journal of Biological Chemistry (Print) , v. 289, p. 7131, 2014.
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CASADEVALL, A. ; FANG, F. C. . Specialized Science. Infection and Immunity (Print) , v. 82, p. 1355-1360, 2014.
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PRADOS-ROSALES, R. ; WEINRICK, B. C. ; PIQUE, D. G. ; JACOBS, W. R. ; CASADEVALL, A. ; RODRIGUEZ, G. M. . Role for Mycobacterium tuberculosis Membrane Vesicles in Iron Acquisition. Journal of Bacteriology (Print) , v. 196, p. 1250-1256, 2014.
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BOURNAZOS, STYLIANOS ; CHOW, SIU-KEI ; ABBOUD, NAREEN ; Casadevall, Arturo ; RAVETCH, JEFFREY V. . Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity. The Journal of Clinical Investigation , v. 124, p. 725-729, 2014.
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RIVERA, J. ; MORGENSTERN, A. ; BRUCHERTSEIFER, F. ; KEARNEY, J. F. ; TURNBOUGH, C. L. ; DADACHOVA, E. ; CASADEVALL, A. . Microbicidal Power of Alpha Radiation in Sterilizing Germinating Bacillus anthracis Spores. Antimicrobial Agents and Chemotherapy (Print) , v. 58, p. 1813-1815, 2014.
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COELHO, CAROLINA ; BOCCA, ANAMELIA L. ; Casadevall, Arturo . The Intracellular Life of Cryptococcus neoformans . Annual Review of Pathology , v. 9, p. 219-238, 2014.
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CASADEVALL, A. ; HANDELSMAN, J. . The Presence of Female Conveners Correlates with a Higher Proportion of Female Speakers at Scientific Symposia. mBio (Online) , v. 5, p. e00846-13-e00846-13, 2013.
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CASADEVALL, A. ; ENQUIST, L. ; Imperiale, M. J. ; KEIM, P. ; OSTERHOLM, M. T. ; RELMAN, D. A. . Redaction of Sensitive Data in the Publication of Dual Use Research of Concern. mBio (Online) , v. 5, p. e00991-13-e00991-13, 2013.
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Albuquerque, P. ; Nicola, A. M. ; NIEVES, E. ; PAES, H. C. ; WILLIAMSON, P. R. ; SILVA-PEREIRA, I. ; CASADEVALL, A. . Quorum Sensing-Mediated, Cell Density-Dependent Regulation of Growth and Virulence in Cryptococcus neoformans. mBio (Online) , v. 5, p. e00986-13-e00986-13, 2013.
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RATH, P. ; HUANG, C. ; WANG, T. ; WANG, T. ; LI, H. ; PRADOS-ROSALES, R. ; ELEMENTO, O. ; CASADEVALL, A. ; NATHAN, C. F. . Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America , v. 110, p. E4790-E4797, 2013.
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BRYAN, RUTH A ; JIANG, ZEWEI ; MORGENSTERN, ALFRED ; BRUCHERTSEIFER, FRANK ; Casadevall, Arturo ; Dadachova, Ekaterina . Radioimmunotherapy of spares bystander mammalian cells. Future Microbiology (Print) , v. 8, p. 1081-1089, 2013.
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ANDES, DAVID ; Casadevall, Arturo . Insights into fungal pathogenesis from the iatrogenic epidemic of Exserohilum rostratum fungal meningitis. Fungal Genetics and Biology (Print) , v. 61, p. 143-145, 2013.
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CASADEVALL, A. ; FANG, F. C. . Is the Nobel Prize good for science?. The FASEB Journal , v. 27, p. 4682-4690, 2013.
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CORDERO, R. J. B. ; BERGMAN, A. ; CASADEVALL, A. . Temporal Behavior of Capsule Enlargement by Cryptococcus neoformans. Eukaryotic Cell , v. 12, p. 1383-1388, 2013.
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Casadevall, Arturo . Progress in understanding fungal pathogenesis. Current Opinion in Microbiology , v. 16, p. 375-376, 2013.
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ERYILMAZ, ERTAN ; JANDA, ALENA ; KIM, JUNGWOOK ; Cordero, Radames J.B. ; COWBURN, DAVID ; Casadevall, Arturo . Global structures of IgG isotypes expressing identical variable regions. Molecular Immunology , v. 56, p. 588-598, 2013.
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STEEN, R. GRANT ; Casadevall, Arturo ; FANG, FERRIC C. . Why Has the Number of Scientific Retractions Increased?. Plos One , v. 8, p. e68397, 2013.
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McClelland, Erin E. ; HOBBS, LETIZIA M. ; Rivera, Johanna ; Casadevall, Arturo ; POTTS, WAYNE K. ; SMITH, JENNIFER M. ; ORY, JERAMIA J. . The Role of Host Gender in the Pathogenesis of Cryptococcus neoformans Infections. Plos One , v. 8, p. e63632, 2013.
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XIA, YUMIN ; JANDA, ALENA ; ERYILMAZ, ERTAN ; Casadevall, Arturo ; PUTTERMAN, CHAIM . The constant region affects antigen binding of antibodies to DNA by altering secondary structure. Molecular Immunology , v. 56, p. 28-37, 2013.
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GARCIA-SOLACHE, M. A. ; IZQUIERDO-GARCIA, D. ; SMITH, C. ; BERGMAN, A. ; CASADEVALL, A. . Fungal Virulence in a Lepidopteran Model Is an Emergent Property with Deterministic Features. mBio (Online) , v. 4, p. e00100-13-e00100-13, 2013.
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QUISPE-TINTAYA, W. ; CHANDRA, D. ; JAHANGIR, A. ; HARRIS, M. ; CASADEVALL, A. ; DADACHOVA, E. ; GRAVEKAMP, C. . Nontoxic radioactive Listeriaat is a highly effective therapy against metastatic pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America , v. 110, p. 8668-8673, 2013.
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Fonseca, Fernanda L. ; GUIMARÃES, ALLAN J. ; KMETZSCH, LÍVIA ; DUTRA, FABIANNO F. ; SILVA, FERNANDA D. ; TABORDA, CARLOS P. ; ARAUJO, GLAUBER DE S. ; Frases, Susana ; Staats, Charley C. ; BOZZA, MARCELO T. ; Schrank, Augusto ; Vainstein, Marilene H. ; Nimrichter, Leonardo ; Casadevall, Arturo ; Rodrigues, Marcio L. . Binding of the wheat germ lectin to Cryptococcus neoformans chitooligomers affects multiple mechanisms required for fungal pathogenesis. Fungal Genetics and Biology (Print) , v. 60, p. 64-73, 2013.
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CHOW, SIU-KEI ; SMITH, CAMERON ; MACCARTHY, THOMAS ; POHL, MARY ANN ; BERGMAN, AVIV ; Casadevall, Arturo . Disease-Enhancing Antibodies Improve the Efficacy of Bacterial Toxin-Neutralizing Antibodies. Cell Host & Microbe , v. 13, p. 417-428, 2013.
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JAIN, NEENA ; Cordero, Radames J. B. ; Casadevall, Arturo ; FRIES, BETTINA C. . Allergen1 regulates polysaccharide structure in Cryptococcus neoformans . Molecular Microbiology (Print) , v. 88, p. 713-727, 2013.
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ZIEGENBALG, ANKE ; Prados-Rosales, Rafael ; JENNY-AVITAL, ELISABETH R. ; KIM, RYUNG S. ; Casadevall, Arturo ; ACHKAR, JACQUELINE M. . Immunogenicity of mycobacterial vesicles in humans: Identification of a new tuberculosis antibody biomarker. Tuberculosis (Edinburgh) , v. 93, p. 448-455, 2013.
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Derengowski, L. d. S. ; PAES, H. C. ; Albuquerque, P. ; TAVARES, A. H. F. P. ; FERNANDES, L. ; SILVA-PEREIRA, I. ; CASADEVALL, A. . The Transcriptional Response of Cryptococcus neoformans to Ingestion by Acanthamoeba castellanii and Macrophages Provides Insights into the Evolutionary Adaptation to the Mammalian Host. Eukaryotic Cell , v. 12, p. 761-774, 2013.
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POHL, M. A. ; RIVERA, J. ; NAKOUZI, A. ; CHOW, S.-K. ; CASADEVALL, A. . Combinations of Monoclonal Antibodies to Anthrax Toxin Manifest New Properties in Neutralization Assays. Infection and Immunity (Print) , v. 81, p. 1880-1888, 2013.
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ACHKAR, JACQUELINE M. ; Casadevall, Arturo . Antibody-Mediated Immunity against Tuberculosis: Implications for Vaccine Development. Cell Host & Microbe , v. 13, p. 250-262, 2013.
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HARRIS, M ; WANG, X G ; JIANG, Z ; PHAETON, R ; KOBA, W ; GOLDBERG, G L ; CASADEVALL, A ; DADACHOVA, E . Combined treatment of the experimental human papilloma virus-16-positive cervical and head and neck cancers with cisplatin and radioimmunotherapy targeting viral E6 oncoprotein. British Journal of Cancer , v. 108, p. 859-865, 2013.
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Casadevall, Arturo ; Pirofski, Liise-anne . fungal meningitis associated with methylprednisolone injections. Future Microbiology (Print) , v. 8, p. 135-137, 2013.
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KLEIN, M. ; LOTEM, M. ; PERETZ, T. ; ZWAS, S. T. ; MIZRACHI, S. ; LIBERMAN, Y. ; CHISIN, R. ; SCHACHTER, J. ; RON, I. G. ; IOSILEVSKY, G. ; KENNEDY, J. A. ; REVSKAYA, E. ; DE KATER, A. W. ; BANAGA, E. ; KLUTZARITZ, V. ; FRIEDMANN, N. ; GALUN, E. ; DENARDO, G. L. ; DENARDO, S. J. ; CASADEVALL, A. ; DADACHOVA, E. ; THORNTON, G. B. . Safety and Efficacy of 188-Rhenium-Labeled Antibody to Melanin in Patients with Metastatic Melanoma. Journal of Skin Cancer , v. 2013, p. 1-8, 2013.
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PERICOLINI, EVA ; ALUNNO, ALESSIA ; GABRIELLI, ELENA ; BARTOLONI, ELENA ; CENCI, ELIO ; CHOW, SIU-KEI ; BISTONI, GIOVANNI ; Casadevall, Arturo ; GERLI, ROBERTO ; VECCHIARELLI, ANNA . The Microbial Capsular Polysaccharide Galactoxylomannan Inhibits IL-17A Production in Circulating T Cells from Rheumatoid Arthritis Patients. Plos One , v. 8, p. e53336, 2013.
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JANDL, THOMAS ; REVSKAYA, EKATERINA ; JIANG, ZEWEI ; HARRIS, MATTHEW ; DOROKHOVA, OLENA ; TSUKROV, DINA ; Casadevall, Arturo ; Dadachova, Ekaterina . Melanoma stem cells in experimental melanoma are killed by radioimmunotherapy. Nuclear Medicine and Biology , v. 40, p. 177-181, 2013.
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Eisenman, Helene C. ; Casadevall, Arturo ; CASADEVALL, A. . Synthesis and assembly of fungal melanin. Applied Microbiology and Biotechnology , v. 93, p. 931-940, 2012.
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Tsirilakis, Kalliope ; Kim, Christy ; Vicencio, Alfin G. ; Andrade, Christopher ; Casadevall, Arturo ; Goldman, David L. ; CASADEVALL, A. . Methylxanthine Inhibit Fungal Chitinases and Exhibit Antifungal Activity. Mycopathologia (1975. Print) , v. 173, p. 83-91, 2012.
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Rivera J ; CASADEVALL, A. . SERUM ALBUMIN DISRUPTS CRYPTOCOCCUS NEOFORMANS AND BACILLUS ANTHRACIS EXTRACELLULAR VESICLES. Cellular Microbiology (Print) , v. 31, p. 1-5, 2012.
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Araujo G de S ; Fonseca FL ; PONTES, B. ; Zancopé-Oliveira RM ; Torres A ; Cordeiro RJ ; CASADEVALL, A. ; Nimrichter L ; Rodrigues, Marcio L ; Garcia ES ; de Sousa W ; Frases S . Capsules from Pathogenic and Non-Pathogenic Cryptococcus spp. Manifest Significant Differences in Structure and Ability to Protect against Phagocytic Cells.. Plos One , v. 7, p. e29561, 2012.
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Yu X ; Prados-Rosales R ; Jenny=Avital ER ; CASADEVALL, A. ; Achkar JM . Comparative Evaluation of Profiles of Antibodies to Mycobacterial Capsular Polysaccharides in Tuberculosis Patients and Controls Stratified by HIV Status.. Clinical and Vaccine Immunology , v. 19, p. 198-208, 2012.
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CASADEVALL, A. . Amoeba provide insight into the origin of virulence in pathogenic fungi.. Advances in Experimental Medicine and Biology , v. 710, p. 1-10, 2012.
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Nicola AM ; CASADEVALL, A. . In Vitro Measurement of Phagocytosis and Killing of Cryptococcus neoformans by Macrophages.. Methods in Molecular Biology (Clifton, N.J.) , v. 844, p. 189-197, 2012.
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CASADEVALL, A. ; Shenk T . The H5N1 Manuscript Redaction Controversy.. MBIO , v. 3, p. pii: e00022-12, 2012.
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Pirofski LA ; CASADEVALL, A. . Q and A What is a pathogen? A question that begs the point. BMC BIOLOGY , v. 10, p. 6, 2012.
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CASADEVALL, A. ; Nakouzi A ; Crippa PR ; Eisner M . Fungal melanins differ in planar stacking distances. Casadevall A, Nakouzi A, Crippa PR, Eisner M.. Plos One , v. 7, p. e30299, 2012.
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Berns KI ; CASADEVALL, A. ; Cohen ML ; Ehrlich SA ; Enquist LW ; Fitch JP ; Franz DR ; Fraser-Liggett CM ; Grant CM ; Imperiale MJ ; Kanabrock J ; Keim PS ; Levy SB ; Lumpkin JR ; Miller JF ; Murch R ; Nance ME ; Osterholm MT ; Relman DA ; Roth JA ; Vidaver AK . Public health and biosecurity. Adaptations of avian flu virus are a cause for concern.. Science (New York, N.Y.) , v. 335, p. 660-1, 2012.
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Berns, Kenneth I. ; Casadevall, Arturo ; Cohen, Murray L. ; Ehrlich, Susan A. ; Enquist, Lynn W. ; Fitch, J. Patrick ; Franz, David R. ; Fraser-Liggett, Claire M. ; Grant, Christine M. ; Imperiale, Michael J. ; Kanabrocki, Joseph ; Keim, Paul S. ; Lemon, Stanley M. ; Levy, Stuart B. ; Lumpkin, John R. ; Miller, Jeffery F. ; Murch, Randall ; Nance, Mark E. ; Osterholm, Michael T. ; Relman, David A. ; Roth, James A. ; Vidaver, Anne K. . Policy: Adaptations of avian flu virus are a cause for concern. Nature (London) , v. 482, p. 153-4, 2012.
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Fang FC ; CASADEVALL, A. . Reply to "likelihood of false-positive results in high-impact journals publishing groundbreaking research". Infection and Immunity (Print) , v. 80, p. 1301, 2012.
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FANG, F. C. ; BENNETT, J. W. ; CASADEVALL, A. . Males Are Overrepresented among Life Science Researchers Committing Scientific Misconduct. mBio (Online) , v. 4, p. e00640-12-e00640-12, 2012.
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CORDERO, R. J. B. ; PONTES, B. ; FRASES, S. ; NAKOUZI, A. S. ; NIMRICHTER, L. ; RODRIGUES, M. L. ; VIANA, N. B. ; CASADEVALL, A. . Antibody Binding to Cryptococcus neoformans Impairs Budding by Altering Capsular Mechanical Properties. The Journal of Immunology (1950) , v. 190, p. 317-323, 2012.
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REVSKAYA, EKATERINA ; CHU, PETER ; HOWELL, ROBERTHA C. ; SCHWEITZER, ANDREW D. ; BRYAN, RUTH A. ; HARRIS, MATTHEW ; GERFEN, GARY ; JIANG, ZEWEI ; JANDL, THOMAS ; KIM, KAMI ; TING, LI-MIN ; SELLERS, RANI S. ; Dadachova, Ekaterina ; Casadevall, Arturo . Compton Scattering by Internal Shields Based on Melanin-Containing Mushrooms Provides Protection of Gastrointestinal Tract from Ionizing Radiation. Cancer Biotherapy & Radiopharmaceuticals , v. 27, p. 570-576, 2012.
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CASADEVALL, A. ; SHENK, T. . The H5N1 Moratorium Controversy and Debate. mBio (Online) , v. 3, p. e00379-12-e00379-12, 2012.
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FANG, F. C. ; STEEN, R. G. ; CASADEVALL, A. . Misconduct accounts for the majority of retracted scientific publications. Proceedings of the National Academy of Sciences of the United States of America , v. 109, p. 17028-17033, 2012.
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ALBUQUERQUE, PRISCILA C. ; Cordero, Radames J.B. ; Fonseca, Fernanda L. ; PERES DA SILVA, ROBERTA ; RAMOS, CAROLINE L. ; MIRANDA, KILDARE R. ; Casadevall, Arturo ; PUCCIA, ROSANA ; NOSANCHUK, JOSHUA D. ; Nimrichter, Leonardo ; GUIMARAES, ALLAN J. ; Rodrigues, Marcio L. . A Paracoccidioides brasiliensis glycan shares serologic and functional properties with cryptococcal glucuronoxylomannan. Fungal Genetics and Biology (Print) , v. 49, p. 943-954, 2012.
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Robertson, E. J. ; WOLF, J. M. ; CASADEVALL, A. . EDTA Inhibits Biofilm Formation, Extracellular Vesicular Secretion, and Shedding of the Capsular Polysaccharide Glucuronoxylomannan by Cryptococcus neoformans. Applied and Environmental Microbiology (Print) , v. 78, p. 7977-7984, 2012.
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JANDA, A. ; ERYILMAZ, E. ; NAKOUZI, A. ; COWBURN, D. ; CASADEVALL, A. . Variable Region Identical Immunoglobulins Differing in Isotype Express Different Paratopes. The Journal of Biological Chemistry (Print) , v. 287, p. 35409-35417, 2012.
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Casadevall, Arturo . Fungi and the Rise of Mammals. PLoS Pathogens (Online) , v. 8, p. e1002808, 2012.
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XIA, YUMIN ; PAWAR, RAHUL D. ; NAKOUZI, ANTONIO S. ; HERLITZ, LEAL ; BRODER, ANNA ; LIU, KUI ; GOILAV, BEATRICE ; FAN, MANXIA ; WANG, LING ; LI, QUAN-ZHEN ; Casadevall, Arturo ; PUTTERMAN, CHAIM . The constant region contributes to the antigenic specificity and renal pathogenicity of murine anti-DNA antibodies. Journal of Autoimmunity (Print) , v. 39, p. 398-411, 2012.
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CASADEVALL, A. ; JANDA, A. . Immunoglobulin isotype influences affinity and specificity. Proceedings of the National Academy of Sciences of the United States of America , v. 109, p. 12272-12273, 2012.
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CHOW, SIU-KEI ; Casadevall, Arturo . Monoclonal Antibodies and Toxins-A Perspective on Function and Isotype. Toxins , v. 4, p. 430-454, 2012.
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Nicola, A. M. ; Albuquerque, P. ; MARTINEZ, L. R. ; DAL-ROSSO, R. A. ; SAYLOR, C. ; DE JESUS, M. ; NOSANCHUK, J. D. ; CASADEVALL, A. . Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans. Infection and Immunity (Print) , v. 80, p. 3065-3076, 2012.
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Casadevall, Arturo ; Pirofski, Liise-anne . Immunoglobulins in Defense, Pathogenesis, and Therapy of Fungal Diseases. Cell Host & Microbe , v. 11, p. 447-456, 2012.
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CASSONE, ANTONIO ; Casadevall, Arturo . Recent progress in vaccines against fungal diseases. Current Opinion in Microbiology , v. 15, p. 427-433, 2012.
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RAMOS, C. L. ; FONSECA, F. L. ; RODRIGUES, J. ; GUIMARAES, A. J. ; CINELLI, L. P. ; MIRANDA, K. ; NIMRICHTER, L. ; CASADEVALL, A. ; TRAVASSOS, L. R. ; RODRIGUES, M. L. . Chitin-Like Molecules Associate with Cryptococcus neoformans Glucuronoxylomannan To Form a Glycan Complex with Previously Unknown Properties. Eukaryotic Cell , v. 11, p. 1086-1094, 2012.
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MUHAMMED, MAGED ; FELDMESSER, MARTA ; SHUBITZ, LISA F. ; LIONAKIS, MICHAIL S. ; SIL, ANITA ; WANG, YAN ; GLAVIS-BLOOM, JUSTIN ; LEWIS, RUSSELL E. ; GALGIANI, JOHN N. ; Casadevall, Arturo ; KONTOYIANNIS, DIMITRIOS P. ; MYLONAKIS, ELEFTHERIOS . Mouse models for the study of fungal pneumonia: A collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus. Virulence (Print) , v. 3, p. 329-338, 2012.
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Casadevall, Arturo . The future of biological warfare. Microbial Biotechnology (Online) , v. 5, p. 584-587, 2012.
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Dadachova, Ekaterina ; KITCHEN, SCOTT G. ; BRISTOL, GREGORY ; BALDWIN, GAYLE COCITA ; REVSKAYA, EKATERINA ; EMPIG, CYRIL ; THORNTON, GEORGE B. ; GORNY, MIROSLAW K. ; ZOLLA-PAZNER, SUSAN ; Casadevall, Arturo . Pre-Clinical Evaluation of a 213Bi-Labeled 2556 Antibody to HIV-1 gp41 Glycoprotein in HIV-1 Mouse Models as a Reagent for HIV Eradication. Plos One , v. 7, p. e31866, 2012.
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CASADEVALL, A. ; SHENK, T. . Mammalian-Transmissible H5N1 Virus: Containment Level and Case Fatality Ratio. mBio (Online) , v. 3, p. e00054-12-e00054-12, 2012.
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CASADEVALL, A. ; Pirofski, Liise-anne . A new synthesis for antibody-mediated immunity. Nature Immunology (Print) , v. 13, p. 21-28, 2011.
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Rodrigues, Marcio L ; Nosanchuk, Joshua D ; Schrank, Augusto ; Vainstein, Marilene H ; Casadevall, Arturo ; Nimrichter, Leonardo . Vesicular transport systems in fungi. Future Microbiology , v. 6, p. 1371-1381, 2011.
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Imperiale, M. J. ; CASADEVALL, A. . Bioterrorism: Lessons Learned Since the Anthrax Mailings. MBIO , v. 2, p. e00232-11-e00232-11, 2011.
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Frases S ; Viana NB ; CASADEVALL, A. . Biophysical methods for the study of microbial surfaces. Frontiers in Microbiology (Online) , v. 2, p. 207, 2011.
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Nicola, A. M. ; Robertson, E. J. ; Albuquerque, P. ; Derengowski, L. d. S. ; CASADEVALL, A. . Nonlytic Exocytosis of Cryptococcus neoformans from Macrophages Occurs In Vivo and Is Influenced by Phagosomal pH. MBIO , v. 2, p. e00167-11-e00167-11, 2011.
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Kmetzsch, LÃ via ; Joffe, Luna S. ; Staats, Charley C. ; de Oliveira, DÃ bora L. ; Fonseca, Fernanda L. ; Cordero, Radames J.B. ; Casadevall, Arturo ; Nimrichter, Leonardo ; Schrank, Augusto ; Vainstein, Marilene H. ; Rodrigues, Marcio L. . Role for Golgi reassembly and stacking protein (GRASP) in polysaccharide secretion and fungal virulence. Molecular Microbiology (Print) , v. 81, p. 206-218, 2011.
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Turick, Charles E. ; Ekechukwu, Amy A. ; Milliken, Charles E. ; Casadevall, Arturo ; Dadachova, Ekaterina . Gamma radiation interacts with melanin to alter its oxidation reduction potential and results in electric current production. Bioelectrochemistry (Amsterdam) , v. 82, p. 69-73, 2011.
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Jiang Z, ; BRYAN, R. A. ; Morgenstern A ; Bruchertseifer F ; CASADEVALL, A. ; Dadachova E . Treatment of early and established Cryptococcus neoformans infection with radiolabeled antibodies in immunocompetent. Antimicrobial Agents and Chemotherapy (Print) , v. 56, p. 552-4, 2011.
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Cordero, Radames J.B. ; PONTES, B. ; Guimaraes AJ ; Rivera J ; Fries B ; Nimrichter L ; Rodrigues M ; Viana NB ; CASADEVALL, A. . Chronological aging is associated with biophysical and chemical changes in the capsule of Cryptococcus neoformans.. Infection and Immunity (Print) , v. 79, p. 4990-5000, 2011.
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Tsirilakis K ; Kim, Christy ; Vicencio AG ; Andrade C ; CASADEVALL, A. ; Goldman DL . Methylxanthine inhibit fungal chitinases and exhibit antifungal activity. Mycopathologia (1975. Print) , v. 173, p. 83-91, 2011.
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Khajo A ; BRYAN, R. A. ; Friedman M ; Burger RM ; CASADEVALL, A. ; Magliozzo RS ; Dadachova, Ekaterina . Protection of melanized Cryptococcus neoformans from lethal dose gamma irradiation involves changes in melanin's chemical structure and paramagnetism. Plos One , v. 6, p. e25092, 2011.
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García-Rodas R ; CASADEVALL, A. ; Rodríguez-Tudela JL ; Cuenca-Estrella M ; Zaragoza O . Cryptococcus neoformans capsular enlargement and cellular gigantism during Galleria mellonella infection. Plos One , v. 6, p. e24485., 2011.
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Rodrigues M ; Nimrichter L ; Cordeiro RJ ; CASADEVALL, A. . Fungal polysaccharides: biological activity beyond the usual structural properties.. Frontiers in Microbiology (Online) , v. 2, p. 171, 2011.
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Vecchiarelli A ; Pericolini E ; Gabrielli E ; Chow SK ; Bistoni F ; Cenci E ; CASADEVALL, A. . Cryptococcus neoformans galactoxylomannan is a potent negative immunomodulator, inspiring new approaches in anti-inflammatory immunotherapy. IMMUNOTHERAPY-UK , v. 3, p. 997-1005, 2011.
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Fang FC ; CASADEVALL, A. . Retracted science and the retraction index. Infection and Immunity (Print) , v. 79, p. 3855-3959, 2011.
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CASADEVALL, A. ; Fang FC ; Pirofski LA . Microbial virulence as an emergent property: consequences and opportunities.. PLoS Pathogens , v. 7, p. e1002136, 2011.
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Dadachova E ; CASADEVALL, A. . Cryptococcus neoformans as a Model for Radioimmunotherapy of Infections. Interdisciplinary Perspectives on Infectious Diseases (Online) , v. 2011, p. 830286, 2011.
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Eisenman HC ; Chow SK ; McClelland EE ; CASADEVALL, A. . The effect of L-DOPA on Cryptococcus neoformans growth and gene expression. Virulence , v. 2, p. 329-336, 2011.
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Chrisman CJ ; Albuquerque, P. ; Guimaraes AJ ; Nieves E ; CASADEVALL, A. . Phospholipids trigger Cryptococcus neoformans capsular enlargement during interactions with amoebae and macropha. PLoS Pathogens , v. 7, p. e1002047, 2011.
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Liu TB ; Wang Y ; Chen Q ; CASADEVALL, A. . The F-Box protein Fbp1 regulates sexual reproduction and virulence in Cryptococcus neoformans. Eukaryotic Cell (Online) , v. 10, p. 791-802, 2011.
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Prados-Rosales R ; Baena A ; Martinez LR ; Luque-Garcia J ; Kalscheuer R ; Nosanchuk JD ; Besra GS ; Chen B ; Jimenez J ; Glatman-Freedman A ; Porcelli SA ; CASADEVALL, A. . Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice.. The Journal of Clinical Investigation , v. 121, p. 1471-1483, 2011.
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de Oliveira, DÃ bora L. ; Nakayasu ES ; Guimaraes AJ ; Sobreira TJ ; Nosanchuk JD ; Cordero, Radames J.B. ; Frases S ; CASADEVALL, A. ; Almeida IC ; Nimrichter L ; Rodrigues M . Biogenesis of extracellular vesicles in yeast: Many questions with few answers.. Communicative & Integrative Biology , v. 3, p. 533-535, 2011.
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Fang FC ; CASADEVALL, A. . Reductionistic and holistic science.. Infection and Immunity (Print) , v. 79, p. 1401-1404, 2011.
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Cordero, Radames J. B. ; Frases, Susana ; Guimarà es, Allan J. ; Rivera, Johanna ; Casadevall, Arturo . Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity. Molecular Microbiology (Print) , v. 79, p. 1101-1117, 2011.
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Harris M ; Jiang Z, ; Goldberg GL ; CASADEVALL, A. ; Dadachova E . Radioimmunotherapy of experimental head and neck squamous cell carcinoma (HNSCC) with E6-specific antibody using a novel HPV-16 positive HNSCC cell line. HEAD NECK ONCOL , v. 3, p. 9, 2011.
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Chow SK ; CASADEVALL, A. . Evaluation of Cryptococcus neoformans galactoxylomannan-protein conjugate as vaccine candidate against murine cryptococcosis. Vaccine (Guildford) , v. 29, p. 1891-1898, 2011.
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Siev M ; Yu X ; Prados-Rosales R ; Martiniuk FT ; CASADEVALL, A. ; Achkar JM . Correlation between serum and plasma antibody titers to mycobacterial antigens. Clinical and Vaccine Immunology , v. 18, p. 173-175, 2011.
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Jesus MD ; Nicola, A. M. ; Chow SK ; Lee IR ; Specht CA ; Levitz SM ; CASADEVALL, A. . Glucuronoxylomannan, galactoxylomannan, and mannoprotein occupy spatially separate and discrete regions in the capsule of Cryptococcus neoformans. Virulence , v. 1, p. 500-508, 2010.
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Bergman A ; CASADEVALL, A. . Mammalian endothermy optimally restricts fungi and metabolic costs. MBIO , v. 1, p. e00212-10, 2010.
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Rivera, Johanna ; Cordeiro RJ ; Nakouzi AS ; Frases S ; Nicola, A. M. ; CASADEVALL, A. . Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins.. Proceedings of the National Academy of Sciences of the United States of America , v. 107, p. 19002-19007, 2010.
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Abboud N ; Chow SK ; Saylor C ; Janda A ; Ravetch JV ; Scharff MD ; CASADEVALL, A. . A requirement for FcγR in antibody-mediated bacterial toxin neutralization. The Journal of Experimental Medicine , v. 207, p. 2395-2405, 2010.
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Lye LF ; Kang SO ; Nosanchuk, Joshua D ; CASADEVALL, A. ; Beverley SM . Phenylalanine hydroxylase (PAH) from the lower eukaryote Leishmania major. Molecular and Biochemical Parasitology (Print) , v. 171, p. 58-67, 2010.
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CASADEVALL, A. ; Fang FC . Reproducible science. Infection and Immunity (Print) , v. 78, p. 4972-4975, 2010.
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Phaeton R ; Harris M ; Jiang Z, ; Wang XG ; Einstein MH ; Goldberg GL ; CASADEVALL, A. ; Dadachova E . Radioimmunotherapy with an antibody to the HPV16 E6 oncoprotein is effective in an experimental cervical tumor expressing low levels of E6. Cancer Biology & Therapy , v. 10, p. 1041-1047., 2010.
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Pericolini E ; Gabrielli E ; Bistoni G ; Cenci E ; Perito S ; Chow SK ; Riuzzi F ; Donato R ; CASADEVALL, A. ; Vecchiarelli A . Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage. Plos One , v. 5, p. e12720., 2010.
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Luo Y ; CASADEVALL, A. . Intracellular cryptococci suppress Fc-mediated cyclin D1 elevation.. Communicative & Integrative Biology , v. 3, p. 390-391, 2010.
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Ostrosky-Zeichner L ; CASADEVALL, A. ; Galgiani JN ; Odds FC ; Rex JH . An insight into the antifungal pipeline: selected new molecules and beyond. Nature Reviews. Drug Discovery (Print) , v. 9, p. 719-727, 2010.
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Garcia-Solache MA ; CASADEVALL, A. . Global warming will bring new fungal diseases for mammals. MBIO , v. 1, p. e00061-10., 2010.
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Chrisman CJ ; Alvarez M ; CASADEVALL, A. . Phagocytosis of Cryptococcus neoformans by, and nonlytic exocytosis from, Acanthamoeba castellanii.. Applied and Environmental Microbiology (Print) , v. 76, p. 6056-6062, 2010.
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Muehlbauer SM ; Lima H Jr ; Goldman DL ; Jacobson LS ; Rivera J ; Goldberg MF ; Palladino MA ; CASADEVALL, A. ; Brojatsch J . Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin. The American Journal of Pathology (Print) , v. 177, p. 735-743, 2010.
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McClelland, Erin E. ; Nicola, André M. ; Prados-Rosales, Rafael ; Casadevall, Arturo . Ab binding alters gene expression in Cryptococcus neoformans and directly modulates fungal metabolism. The Journal of Clinical Investigation , v. 120, p. 1355-1361, 2010.
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Casadevall, Arturo . Cryptococci at the brain gate: break and enter or use a Trojan horse?. The Journal of Clinical Investigation , v. 120, p. 1389-1392, 2010.
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BRYAN, R. A. ; Jiang Z, ; Howell RC ; Morgenstern A ; Bruchertseifer F ; CASADEVALL, A. ; Dadachova E . Radioimmunotherapy is more effective than antifungal treatment in experimental cryptococcal infection. The Journal of Infectious Diseases , v. 202, p. 633-637, 2010.
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Zaragoza O ; García-Rodas R ; Nosanchuk JD ; Cuenca-Estrella M ; Rodríguez-Tudela JL ; CASADEVALL, A. . Fungal cell gigantism during mammalian infection. PLoS Pathogens , v. 6, p. e100094, 2010.
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CASADEVALL, A. ; Imperiale MJ . Destruction of microbial collections in response to select agent and toxin list regulations. BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE , v. 8, p. 151-154, 2010.
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Oliveira DL ; Nakayasu ES, ; Joffe LS ; Guimaraes AJ ; Sobreira TJ ; Nosanchuk JD ; Cordero, Radames J. B. ; Frases S ; CASADEVALL, A. ; Almeida IC ; Nimrichter L ; Rodrigues M . Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis.. Plos One , v. 5, p. e11113, 2010.
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Fonseca FL ; Nohara LL ; Cordero, Radames J. B. ; Frases S ; CASADEVALL, A. ; Almeida IC ; Nimrichter L ; Rodrigues M . Immunomodulatory effects of serotype B glucuronoxylomannan from Cryptococcus gattii correlate with polysaccharide diameter. Infection and Immunity (Print) , v. 78, p. 3861-3870, 2010.
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Schweitzer AD ; Revskaya E ; Chu P ; Pazo V ; Friedman M ; Nosanchuk, Joshua D ; Cahill S ; Frases S ; CASADEVALL, A. ; Dadachova E . Melanin-covered nanoparticles for protection of bone marrow during radiation therapy of cancer.. International Journal of Radiation Oncology, Biology, Physics , v. 78, p. 1494-502, 2010.
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Winterroth L ; Rivera J ; Nakouzi A ; Dadachova E ; CASADEVALL, A. . Neutralizing monoclonal antibody to edema toxin and its effect on murine anthra. Infection and Immunity (Print) , v. 78, p. 2890-2896, 2010.
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Janda A ; CASADEVALL, A. . Circular Dichroism reveals evidence of coupling between immunoglobulin constant and variable region secondary structure. Molecular Immunology , v. 47, p. 1421-1425, 2010.
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Frager SZ ; Chrisman CJ ; Shakked R ; CASADEVALL, A. . Paramecium species ingest and kill the cells of the human pathogenic fungus Cryptococcus neoforman. Medical Mycology (Oxford. Online) , v. 48, p. 775-779, 2010.
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Luke TC ; CASADEVALL, A. ; Watowich SJ ; Hoffman SL ; Beigel JH ; Burgess TH . Hark back: passive immunotherapy for influenza and other serious infections. Critical Care Medicine (Online) , v. 38, p. e66-73, 2010.
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Oliveira DL ; Freire-de-Lima CG ; Nosanchuk JD ; CASADEVALL, A. ; Rodrigues, Marcio L ; Nimrichter L . Extracellular vesicles from Cryptococcus neoformans modulate macrophage functions. Infection and Immunity (Print) , v. 78, p. 1601-1609, 2010.
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Phaeton R ; Wang XG ; Einstein MH ; Goldberg GL ; CASADEVALL, A. ; Dadachova E . The influence of proteasome inhibitor MG132, external radiation, and unlabeled antibody on the tumor uptake and biodistribution of (188)re-labeled anti-E6 C1P5 antibody in cervical cancer in mice. Cancer , v. 116, p. 1067-1074, 2010.
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Achkar JM ; Jenny-Avital E ; Yu X ; Burger S ; Leibert E ; Bilder PW ; Almo SC ; CASADEVALL, A. ; Laal S . Antibodies against immunodominant antigens of Mycobacterium tuberculosis in subjects with suspected tuberculosis in the United States compared by HIV status. Clinical and Vaccine Immunology , v. 17, p. 384-392, 2010.
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Guimaraes AJ ; Frases S ; Cordeiro RJ ; Nimrichter L ; CASADEVALL, A. ; Nosanchuk JD . Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo. Cellular Microbiology (Print) , v. 12, p. 740-753, 2010.
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CASADEVALL, A. ; Relman DA . Microbial threat lists: obstacles in the quest for biosecurity?. Nature Review, Microbiology (Print) , v. 8, p. 149-154, 2010.
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De Jesus M ; Chow SK ; Cordeiro RJ ; Frases S ; CASADEVALL, A. . Galactoxylomannans from Cryptococcus neoformans varieties neoformans and grubii are structurally and antigenically variable. Eukaryotic Cell , v. 9, p. 1018-1028, 2010.
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Biron CA ; CASADEVALL, A. . On immunologists and microbiologists: ground zero in the battle for interdisciplinary knowledge.. MBIO , v. 1, p. e002, 2010.
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Fang FC ; CASADEVALL, A. . Lost in translation--basic science in the era of translational research. Infection and Immunity (Print) , v. 78, p. 563-566, 2010.
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Luo Y ; Pollard JW ; CASADEVALL, A. . Fcgamma receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway.. Journal of Biological Chemistry (Online) , v. 285, p. 4232-42, 2010.
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Saylor C ; Dadachova E ; CASADEVALL, A. . Murine IgG1 and IgG3 isotype switch variants promote phagocytosis of Cryptococcus neoformans through different receptors. The Journal of Immunology (1950) , v. 184, p. 336-43, 2010.
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Nakouzi A ; Zhang T ; Oscarson S ; CASADEVALL, A. . The common Cryptococcus neoformans glucuronoxylomannan M2 motif elicits non-protective antibodies. Vaccine (Guildford) , v. 27, p. 3513-3518, 2009.
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Pericolini E ; Gabrielli E ; Cenci E ; De Jesus M ; CASADEVALL, A. ; Vecchiarelli A . Involvement of glycoreceptors in galactoxylomannan-induced T cell death. Journal of Immunology (Baltimore) , v. 182, p. 6003-6010, 2009.
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Alvarez M ; Burn T ; Luo Y ; Pirofski LA ; CASADEVALL, A. . The outcome of Cryptococcus neoformans intracellular pathogenesis in human monocytes. BMC Microbiology (Online) , v. 9, p. 51, 2009.
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Pirofski LA ; CASADEVALL, A. . Rethinking T cell immunity in oropharyngeal candidiasis.. Journal of Experimental Medicine , v. 206, p. 269-273, 2009.
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Saylor C ; Dadachova E ; CASADEVALL, A. . Monoclonal antibody-based therapies for microbial diseases.. Vaccine (Guildford) , v. 27, p. G38-46, 2009.
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Robert VA ; CASADEVALL, A. . Vertebrate endothermy restricts most fungi as potential pathogens. The Journal of Infectious Diseases , v. 200, p. 1623-26, 2009.
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Franz DR ; Ehrlich SA ; CASADEVALL, A. ; Imperiale MJ ; Keim PS . The "nuclearization" of biology is a threat to health and security.. BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE , v. 7, p. 243-4, 2009.
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Martinez LR ; Mihu MR ; Han G ; Frases S ; Cordeiro RJ ; CASADEVALL, A. ; Friedman AJ ; Friedman M ; Nosanchuk JD . The use of chitosan to damage Cryptococcus neoformans biofilms. Biomaterials (Guildford) , v. 31, p. 669-79, 2009.
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Schweitzer AD ; Howell RC ; Jiang Z, ; BRYAN, R. A. ; Gerfen G ; Chen CC ; Cahill S ; CASADEVALL, A. ; Dadachova E . Physico-chemical evaluation of rationally designed melanins as novel nature-inspired radioprotectors. Plos One , v. 4, p. e7229, 2009.
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Oliveira DL ; Nimrichter L ; Frases S ; Faull KF ; Miranda K ; CASADEVALL, A. ; Rodrigues M . Cryptococcus neoformans cryoultramicrotomy and vesicle fractionation reveals an intimate association between membrane lipids and glucuronoxylomannan. Fungal Genetics and Biology (Print) , v. 46, p. 956-63, 2009.
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Eisenman HC ; Frases S ; Nicola, A. M. ; Rodrigues M ; CASADEVALL, A. . Vesicle-associated melanization in Cryptococcus neoformans. Microbiology (New York) , v. 155, p. 3860-7, 2009.
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Silva MB ; Thomaz L ; Marques AF ; Svidzinski AE ; Nosanchuk JD ; CASADEVALL, A. ; Travassos LR ; Taborda C . Resistance of melanized yeast cells of Paracoccidioides brasiliensis to antimicrobial oxidants and inhibition of phagocytosis using carbohydrates and monoclonal antibody to CD1. Memórias do Instituto Oswaldo Cruz (Impresso) , v. 104, p. 644-8, 2009.
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CASADEVALL, A. ; Pirofski LA . Virulence factors and their mechanisms of action: the view from a damage-response framework. Journal of Water and Health , v. 7, p. S2-S1, 2009.
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Rivera J ; Nakouzi AS ; Morgenstern A ; Bruchertseifer F ; Dadachova E ; CASADEVALL, A. . Radiolabeled antibodies to Bacillus anthracis toxins are bactericidal and partially therapeutic in experimental murine anthrax.. Antimicrobial Agents and Chemotherapy (Print) , v. 53, p. 4860-8, 2009.
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Frases S ; PONTES, B. ; Nimrichter L ; Rodrigues M ; Viana NB ; CASADEVALL, A. . The elastic properties of the Cryptococcus neoformans capsule. Biophysical Journal (Print) , v. 97, p. 937-45, 2009.
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De Jesus M ; Nicola, A. M. ; Frases S ; Lee IR ; Mieses S ; CASADEVALL, A. . Galactoxylomannan-mediated immunological paralysis results from specific B cell depletion in the context of widespread immune system damage. The Journal of Immunology (1950. Online) , v. 183, p. 3885-94, 2009.
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CASADEVALL, A. ; Fang FC . Important science--it's all about the SPIN. Infection and Immunity (Print) , v. 77, p. :4177-80, 2009.
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Luo Y ; Isaac BM ; CASADEVALL, A. ; Cox D . Phagocytosis inhibits F-actin-enriched membrane protrusions stimulated by fractalkine (CX3CL1) and colony-stimulating factor 1. Infection and Immunity (Print) , v. 77, p. 4487-95, 2009.
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Abboud N ; De Jesus M ; Nakouzi AS ; Cordeiro RJ ; Pujato M ; Fiser A ; Rivera J ; CASADEVALL, A. . Identification of linear epitopes in Bacillus anthracis protective antigen bound by neutralizing antibodies.. Journal of Biological Chemistry (Online) , v. 284, p. 25077-8, 2009.
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Fonseca, Fernanda L. ; Nimrichter L ; Cordero, Radames J. B. ; Frases S ; Rodrigues J ; Goldman DL ; Andruszkiewicz R ; Milewski S ; Travassos LR ; CASADEVALL, A. ; Rodrigues M . Role for chitin and chitooligomers in the capsular architecture of Cryptococcus neoformans. Eukaryotic Cell , v. 8, p. 1543-53, 2009.
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CASADEVALL, A. ; Fang FC . Mechanistic science. Infection and Immunity (Print) , v. 77, p. 3517-9, 2009.
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CASADEVALL, A. . The case for pathogen-specific therapy. Expert Opinion on Pharmacotherapy , v. 10, p. 1699-703, 2009.
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Nicola, A. M. ; Frases S ; CASADEVALL, A. . Lipophilic dye staining of Cryptococcus neoformans extracellular vesicles and capsule. Eukaryotic Cell , v. 8, p. 1373-80, 2009.
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Zaragoza O ; Rodrigues M ; De Jesus M ; Frases S ; Dadachova E ; CASADEVALL, A. . The capsule of the fungal pathogen Cryptococcus neoformans. Advances in Applied Microbiology , v. 68, p. 133-216, 2009.
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Rodrigues M ; Fonseca, Fernanda L. ; Frases S ; CASADEVALL, A. ; Nimrichter L . The still obscure attributes of cryptococcal glucuronoxylomannan. Medical Mycology (Oxford. Print) , v. 47, p. 783-8, 2009.
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CASADEVALL, A. ; Nosanchuk JD ; Williamson P ; Rodrigues, Marcio L . Vesicular transport across the fungal cell wall.. Trends in Microbiology (Regular ed.) , v. 17, p. 158-62, 2009.
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Revskaya E ; Jongco AM ; Howell RC ; Koba W ; Guimaraes AJ ; Nosanchuk JD ; CASADEVALL, A. ; Dadachova E . Radioimmunotherapy of experimental human metastatic melanoma with melanin-binding antibodies and in combination with dacarbazine.. Clinical Cancer Research (Print) , v. 15, p. 2373-9, 2009.
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Fonseca, Fernanda L. ; Frases S ; CASADEVALL, A. ; Fischman-Gompertz O ; Nimrichter L ; Rodrigues M . Structural and functional properties of the Trichosporon asahii glucuronoxylomannan.. Fungal Genetics and Biology (Print) , v. 46, p. 496-505, 2009.
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Robertson, E. J. ; CASADEVALL, A. . Antibody-mediated immobilization of Cryptococcus neoformans promotes biofilm formation.. Applied and Environmental Microbiology (Print) , v. 75, p. 2528-33, 2009.
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CASADEVALL, A. ; Fang FC . Is peer review censorship?. Infection and Immunity (Print) , v. 77, p. 1273-4, 2009.
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Panepinto J ; Komperda K ; Frases, Susana ; Park YD ; Djordjevic JT ; CASADEVALL, A. ; Williamson PR . Sec6-dependent sorting of fungal extracellular exosomes and laccase of Cryptococcus neoformans. Molecular Microbiology (Print) , v. 71, p. 1165-76, 2009.
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Dadachova E ; CASADEVALL, A. . Radioimmunotherapy of infectious diseases.. Seminars in Nuclear Medicine , v. 39, p. 146-53, 2009.
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Nosanchuk JD ; Nimrichter L ; CASADEVALL, A. ; Rodrigues M . A role for vesicular transport of macromolecules across cell walls in fungal pathogenesis. Communicative & Integrative Biology , v. 1, p. 37-39, 2009.
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Fang FC ; CASADEVALL, A. . NIH peer review reform--change we need, or lipstick on a pig?. Infection and Immunity (Print) , v. 77, p. 929-32, 2009.
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Frases S ; PONTES, B. ; Nimrichter L ; Viana NB ; Rodrigues M ; CASADEVALL, A. . Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules. Proceedings of the National Academy of Sciences of the United States of America , v. 106, p. 1228-33, 2009.
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BRYAN, R. A. ; Jiang Z, ; Huang X ; Morgenstern A ; Bruchertseifer F ; Sellers RS ; CASADEVALL, A. ; Dadachova E . Radioimmunotherapy is effective against high-inoculum Cryptococcus neoformans infection in mice and does not select for radiation-resistant cryptococcal cells. Antimicrobial Agents and Chemotherapy (Print) , v. 53, p. 1679-82, 2009.
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Bliska JB ; CASADEVALL, A. . Intracellular pathogenic bacteria and fungi--a case of convergent evolution?. Nature Review, Microbiology (Print) , v. 7, p. 165-71, 2009.
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De Jesus M ; Nicola, A. M. ; Rodrigues M ; Janbon G ; CASADEVALL, A. . Capsular localization of the Cryptococcus neoformans polysaccharide component galactoxylomannan. Eukaryotic Cell (Online) , v. 8, p. 96-103, 2009.
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Zaragoza O ; Chrisman CJ ; Castelli MV ; Frases S ; Cuenca-Estrella M ; Rodríguez-Tudela JL ; CASADEVALL, A. . Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival.. Cellular Microbiology , v. 10, p. 2043-2057, 2008.
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Nicola AM ; CASADEVALL, A. ; Goldman DL . Fungal killing by mammalian phagocytic cells.. Current Opinion in Microbiology , v. 11, p. 313-317, 2008.
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Maglione PJ ; Xu J ; CASADEVALL, A. ; Chan J . Fc gamma receptors regulate immune activation and susceptibility during Mycobacterium tuberculosis infection.. Journal of Immunology (Baltimore) , v. 180, p. 3329-3338, 2008.
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De Jesus M ; Park CG ; Su Y ; Goldman DL ; Steinman RM ; CASADEVALL, A. . Spleen deposition of Cryptococcus neoformans capsular glucuronoxylomannan in rodents occurs in red pulp macrophages and not marginal zone macrophages expressing the C-type lectin SIGN-R1.. Medical Mycology (Oxford) , v. 46, p. 153-162, 2008.
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Dadachova E ; CASADEVALL, A. . Host and microbial cells as targets for armed antibodies in the treatment of infectious diseases.. Current Opinion in Investigational Drugs , v. 9, p. 184-188, 2008.
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Pirofski LA ; CASADEVALL, A. . The damage-response framework of microbial pathogenesis and infectious diseases.. Advances in Experimental Medicine and Biology , v. 635, p. 135-146, 2008.
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CASADEVALL, A. ; Ehrlich SA ; Franz DR ; Imperiale MJ ; Keim PS . Biodefense research: a win-win challenge. BIOSECURITY AND BIOTERRORISM-BIODEFENSE STRATEGY PRACTICE AND SCIENCE , v. 6, p. 291-2, 2008.
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Eisenman HC ; CASADEVALL, A. ; McClelland EE . New Insights on the Pathogenesis of Invasive Cryptococcus neoformans Infection.. Current Infectious Disease Reports , v. 9, p. 457-464, 2007.
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CASADEVALL, A. . Determinants of virulence in the pathogenic fungi.. Fungal Biology Reviews , v. 21, p. 130-132, 2007.
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CASADEVALL, A. ; Pirofski LA . Antibody-mediated protection through cross-reactivity introduces a fungal heresy into immunological dogma.. Infection and Immunity , v. 75, p. 5074-5078, 2007.
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Alvarez M ; CASADEVALL, A. . Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophages.. BMC immunology (Online) , v. 8, p. 16, 2007.
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Zaragoza O ; Alvarez M ; Telzak A ; Rivera J ; CASADEVALL, A. . The relative susceptibility of mouse strains to pulmonary Cryptococcus neoformans infection is associated with pleiotropic differences in the immune response.. Infection and Immunity , v. 75, p. 2729-2739, 2007.
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McClelland EE ; CASADEVALL, A. . Strain-related differences in antibody-mediated changes in gene expression are associated with differences in capsule and location of binding.. Fungal Genetics and Biology (Print) , 2012.
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Albuquerque P ; CASADEVALL, A. . Quorum sensing in fungi - a review. Albuquerque P, Casadevall A.. Mycopathologia (1975. Print) , 2012.
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Coelho C ; Tesfa L ; Zhang J, ; Rivera J ; CASADEVALL, A. . Analysis of Cell cycle and Replication of Mouse Macrophages after in vivo and in vitro Cryptococcus neoformans infection using Laser Scanning Cytometry.. Infection and Immunity (Print) , 2012.
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Goldman DL ; Li X ; Tsirilakis K ; Andrade C ; CASADEVALL, A. ; Vicencio AG . Increased chitinase expression and fungal-specific antibodies in the bronchoalveolar lavage fluid of asthmatic children. Clinical and Experimental Allergy (Print) , 2011.
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BRYAN, R. A. ; Guimaraes AJ ; Nosanchuk, Joshua D ; CASADEVALL, A. ; Dadachova E . Toward Developing a Universal Treatment for Fungal Disease Using Radioimmunotherapy Targeting Common Fungal Antigens.. Mycopathologia (1975. Print) , 2011.
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Del Poeta M ; CASADEVALL, A. . Ten Challenges on Cryptococcus and Cryptococcosis. Mycopathologia (1975. Print) , 2011.
Projetos de pesquisa
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2004 - 2006
Mining slime mold for susceptibility genes to fungi, Situação: Concluído; Natureza: Pesquisa. , Integrantes: Arturo Casadevall - Coordenador.
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2003 - Atual
B cell related prophylaxis and therapeutics, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Arturo Casadevall - Coordenador.
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1997 - Atual
Synergy of Host Defense Mechanisms in the Lung, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Arturo Casadevall - Coordenador.
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1993 - Atual
Molecular Characterization of C. neoformans Antibodies, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Arturo Casadevall - Coordenador.
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1993 - Atual
Protective Antibodies for Cryptococcal Infections, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Arturo Casadevall - Coordenador.
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1993 - Atual
Biology of Fungal Melanin, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Arturo Casadevall - Coordenador.
Histórico profissional
Endereço profissional
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Albert Einstein College of Medicine, Department of Microbiology and Immunology. , 1300 Morris Park ave room F411, 10461 - Bronx, - Estados Unidos, Telefone: (718) 4303766, URL da Homepage:
Experiência profissional
1992 - 1996
Albert Einstein College of Medicine, EinsteinVínculo: Formal labor contract, Enquadramento Funcional: Assistant Professor, Regime: Dedicação exclusiva.
Atividades
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Direção e administração, Department of Microbiology and Immunology, .,Cargo ou função, Head of Department.
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Pesquisa e desenvolvimento , Microbiology and Immunology, .,Linhas de pesquisa
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Direção e administração, Division of Infectious Diseases, .,Cargo ou função, Head of Department.
Criando um monitoramento
Nossos robôs irão buscar nos nossos bancos de dados todos os processos de Arturo Casadevall e sempre que o nome aparecer em publicações dos Diários Oficiais, avisaremos por e-mail e pelo painel do usuário
Criando um monitoramento
Nossos robôs irão buscar nos nossos bancos de dados todas as movimentações desse processo e sempre que o processo aparecer em publicações dos Diários Oficiais e nos Tribunais, avisaremos por e-mail e pelo painel do usuário
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