Peter Lees Pearson

Peter Pearson graduou-se em Biologia pela Universidade de Liverpool (1962) e obteve seu doutorado em Genética pela Universidade de Durham (1967). De 1965 a 1972, trabalhou para o Conselho Britânico de Pesquisa Médica em Oxford. Em um serviço de genética clínica, fez seu treinamento como clínico citogeneticista, pesquisou técnicas de coloração para cromossomes e contribuiu para o desenvolvimento de nomenclatura para citogenética humana (Conferência de Paris, 1971). Em 1972, mudou-se para Holanda e estabeleceu um serviço de citogenética clínica na Universidade de Leiden, onde se tornou chefe de Departamento de 1977 a 1989. Durante esse período, foi vice-presidente do Conselho Holandês de Genética Humana (1981-1987) e representou a Holanda no Comitê da União Européia (EU) para Pesquisa Médica, e também presidiu o Comitê da EU de genoma humano. Em 1989, mudou-se para os EUA e estabeleceu e se tornou o primeiro diretor do Genome Database (DGV) sediado na Universidade Johns Hopkins, Baltimore, onde era também diretor do banco de dados OMIM (Online Mendelian Inheritance in Man). Em 1995, ele retornou à Holanda para estabelecer um novo departamento de Genética Médica na Universidade de Utrecht. É membro da Academia Holandesa de Ciências e Presidente da Sociedade Internacional de Cromossomo e Genoma. Em 2005 mudou-se para o Brasil, e foi 2 vezes professor visitante nesse período (CNPq e FAPESP), onde tem estado envolvido em ensino e pesquisa, atuando principalmente nos seguintes temas: linkage disequilibrium, genetics, human ovarium aging. Atividades científicas atuais: P L Pearson é co-coordenador do Centro de células tronco para doenças genéticas humanas (CETGEN), recentemente estabelecido no Instituto de Biociências da USP e afiliado ao Centro de Estudos do Genoma Humano (CEPID - FAPESP). Outras atividades incluem desenvolver e ministrar um curso para pós-graduandos "English for Scientists" e continuar nas atividades de pesquisa em envelhecimento ovariano, com ênfase no impacto do tamanho da repetição do gene para síndrome do X Frágil, em colaboração como a Professora Angela Morgante; um estudo epidemiológico sobre fertilidade feminina e outro sobre a contribuição da avó na sobrevivência do neto usando dados de uma população Franco-Canadense é desenvolvido em colaboração com Professor Paulo Otto; investigar o uso de cálculo de penetrância variável para melhorar as estimativas de ligação e risco genético em doenças com antecipação aparente, com Prof Paulo Otto; desenvolver um novo método de análise de associação entre genes e doenças baseado em estudos familiais, em vez de populacionais.

Informações coletadas do Lattes em 10/11/2022

Acadêmico

Formação acadêmica

Doutorado em Genética

1963 - 1967

Durham University
Título: citogenetica de plantas
Orientador: nao sabido

Graduação em Biologia

1959 - 1962

University of Liverpool

Orientou

T

Verbeek; The localisation and identification of novel SCA genes in the Dutch autosomal dominant cerebellar ataxia population; 2005; Tese (Doutorado em Medical Genetics) - VU University Medical Center, Preventie Fondsen; Orientador: Peter Lees Pearson;

SC Bakker

Unravelling the genetics of Schizophrenia and ADHD; 2005; Tese (Doutorado em Medical Genetics) - VU University Medical Center, Makaria Stichting; Orientador: Peter Lees Pearson;

M

van Belzen; Coeliac disease: investigation of the genetic factors underlying coeliav disease; 2003; Tese (Doutorado em Medical Genetics) - VU University Medical Center, Maag Lever Darm Stichting; Orientador: Peter Lees Pearson;

K

van Asselt; Age at manopause : A genetic-epidemiologic study; 2003; Tese (Doutorado em Medical Genetics) - VU University Medical Center, Organon NV; Orientador: Peter Lees Pearson;

H

Kok; Age at menopause: A genetic epidemiologic study; 2003; Tese (Doutorado em Medical Genetics) - VU University Medical Center, Organon NV; Orientador: Peter Lees Pearson;

J

van Tilburg; The Breda Study: search for genetic factors involved in type 2 diabetis mellitus; 2002; Tese (Doutorado em Medical Genetics) - VU University Medical Center, Dutch Diabetes Foundation; Orientador: Peter Lees Pearson;

A

J; A; van de Sluis; Identification of a copper toxicosis gene in Bedlingto terriers; 2002; Tese (Doutorado em Medical Genetics) - VU University Medical Center, Medigon; Orientador: Peter Lees Pearson;

F

J; Hes; Von Hippel-Lindau disease: clinical and genetic investigations in the Netherlands; 2000; Tese (Doutorado em Medical Genetics) - VU University Medical Center, Preventie Fondsen; Orientador: Peter Lees Pearson;

M

Skraastad; Genetic mapping and predictive diagnosis of Huntington disease; 1992; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Preventie Fondsen; Orientador: Peter Lees Pearson;

H

Veenema; Clinical, cytogenetic and molecular aspects of the Fragile-X syndromw; 1989; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center,; Orientador: Peter Lees Pearson;

P

Devilee; Towards a molecular understanding of human breast cancer; 1989; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Koningin Wilhelmina Fonds; Orientador: Peter Lees Pearson;

E

Bakker; Duchenne Muscular Dystrophy: carrier detection and prenatal diagnosis by DNA analysis, new mutation and mosaicism; 1989; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Preventie Fondsen; Orientador: Peter Lees Pearson;

A

M; Vossepoel; Analysis of image segmentation for automated chromosome identification; 1987; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Jan Dekker Stichting; Orientador: Peter Lees Pearson;

M

H; Hofker; Development of genetic markers in the detection of inherited diseases: application in diagnosis of Duchenne musculat dystrophy; 1987; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Medigon; Orientador: Peter Lees Pearson;

G

C; Beverstock; Somatic cell studies in Huntington's disease; 1985; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Preventie Fondsen; Orientador: Peter Lees Pearson;

H

T; C; M; van den Berg; The automation of metaphase finding and chromosome analysis; 1984; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Stichting voor Zuiver Wetenschappijk Onderzoek; Orientador: Peter Lees Pearson;

N

J; Leschot; On prenatal diagnosis; 1982; Tese (Doutorado em Medical Genetics) - Universiteit van Amsterdam,; Coorientador: Peter Lees Pearson;

F

C; M; van Meel; In vitro reactivation of human spermatozoa; 1980; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Medigon; Orientador: Peter Lees Pearson;

J

Garver; Genome organization in primates; 1980; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center,; Orientador: Peter Lees Pearson;

M

Verjaal; On prenatal diagnosis; 1980; Tese (Doutorado em Medical Genetics) - Universiteit van Amsterdam,; Coorientador: Peter Lees Pearson;

K

Madan; Contribution of banding techniques to the study of variation and behaviour of chromosomes; 1978; Tese (Doutorado em medical genetics) - Vrije Universiteit Medisch Centrum,; Coorientador: Peter Lees Pearson;

J

M; J; C; Scheres; Differential staining of human chromosomes; 1976; Tese (Doutorado em Medical Genetics) - Radboud University Nijmegen Medical Centre, Academic Hospital Nijmegen; Coorientador: Peter Lees Pearson;

J

Geraedts; Constituitive heterochromatin asa marker for chromosomal studies in human somaticd cells and spermatozoz; 1975; Tese (Doutorado em Medical Genetics) - Leiden University Medical Center, Academic Hospital Leiden; Orientador: Peter Lees Pearson;

Produções bibliográficas

  • DANTAS, VITOR G.L. ; FREITAS, ERIKA L. ; DELLA-ROSA, VALTER A. ; Lezirovitz, Karina ; DE MORAES, ANA MARIA S.M. ; RAMOS, SILVIA B. ; OITICICA, JEANNE ; ALVES, LEANDRO U. ; Pearson, Peter L. ; Rosenberg, Carla ; MINGRONI-NETTO, REGINA C. . Novel partial duplication of EYA1 causes branchiootic syndrome in a large Brazilian family. International Journal of Audiology , v. x, p. 1-6, 2015.

  • Krepischi, Ana Cristina Victorino ; CAPELLI, LEONARDO PIRES ; SILVA, AMANDA GONÇALVES ; DE ARAÚJO, ÉRICA SARA SOUZA ; Pearson, Peter Lees ; HECK, BENJAMIN ; DA COSTA, CECÍLIA MARIA LIMA ; DE CAMARGO, BEATRIZ ; Rosenberg, Carla . Large germline copy number variations as predisposing factor in childhood neoplasms. Future Oncology , v. 10, p. 1627-1633, 2014.

  • SILVA, AMANDA G ; KREPISCHI, ANA CV ; PEARSON, PETER L ; HAINAUT, PIERRE ; Rosenberg, Carla ; ACHATZ, MARIA ISABEL . The profile and contribution of rare germline copy number variants to cancer risk in Li-Fraumeni patients negative for TP53 mutations. Orphanet Journal of Rare Diseases , v. 9, p. 63, 2014.

  • IZZO, GISELLE ; FREITAS, ÉRIKA L. ; KREPISCHI, ANA CRISTINA V. ; Pearson, Peter L. ; VASQUES, LUCIANA R. ; PASSOS-BUENO, MARIA RITA S. ; BERTOLA, DÉBORA R. ; Rosenberg, Carla . A microduplication of 5p15.33 reveals CLPTM1L as a candidate gene for cleft lip and palate. European Journal of Medical Genetics , v. x, p. x, 2013.

  • SILVA, AMANDA G ; KREPISCHI, ANA CV ; TORREZAN, GIOVANA T ; CAPELLI, LEONARDO P ; CARRARO, DIRCE M ; D'ANGELO, CARLA S ; KOIFFMANN, CELIA P ; Zatz, Mayana ; NASLAVSKY, MICHEL S ; Masotti, Cibele ; OTTO, PAULO A ; ACHATZ, MARIA IW ; MILLS, RYAN E ; LEE, CHARLES ; PEARSON, PETER L ; Rosenberg, Carla . Does germ-line deletion of the PIP gene constitute a widespread risk for cancer?. European Journal of Human Genetics , v. x, p. x, 2013.

  • VILLELA, DARINE ; KIMURA, LILIAN ; SCHLESINGER, DAVID ; GONÇALVES, AMANDA ; Pearson, Peter L. ; SUEMOTO, CLAUDIA K. ; PASQUALUCCI, CARLOS ; KREPISCHI, ANA CRISTINA ; GRINBERGAND, LEA T. ; Rosenberg, Carla . Germline DNA copy number variation in individuals with Argyrophilic grain disease reveals CTNS as a plausible candidate gene. Genetics and Molecular Biology (Impresso) , v. 36, p. 498-501, 2013.

  • Krepischi, Ana Cristina Victorino ; Pearson, Peter Lees ; Rosenberg, Carla . Germline copy number variations and cancer predisposition. Future Oncology , v. 8, p. 441-450, 2012.

  • SILVA, AMANDA G ; ACHATZ, ISABEL MARIA W ; KREPISCHI, ANA CV ; PEARSON, PETER L ; Rosenberg, Carla . Number of rare germline CNVs and TP53 mutation types. Orphanet Journal of Rare Diseases , v. x, p. x, 2012.

  • Knauff, Erik A.H. ; Blauw, Hylke M. ; Pearson, Peter L. ; Kok, Klaas ; Wijmenga, Cisca ; Veldink, Jan H. ; van den Berg, Leonard H. ; Bouchard, Philippe ; Fauser, Bart C.J.M. ; Franke, Lude . Copy number variants on the X chromosome in women with primary ovarian insufficiency. Fertility and Sterility , p. 1584-1588, 2011.

  • Krepischi, Ana Cristina Victorino ; Knijnenburg, Jeroen ; Bertola, Debora Romeo ; Kim, Chong Ae ; Pearson, Peter Lees ; Bijlsma, Emilia ; Szuhai, Karoly ; Kok, Fernando ; Vianna-Morgante, Angela Maria ; Rosenberg, Carla . Two distinct regions in 2q24.2-q24.3 associated with idiopathic epilepsy. Epilepsia (Copenhagen) , v. 51, p. 2457-2460, 2010.

  • Muniz, Viviane P. ; Senkevics, Adriano S. ; Zilbersztajn, Dinorah ; Gurgel-Giannetti, Juliana ; Silva, Helga C. ; Yamamoto, Lydia U. ; Pavanello, Rita C.M. ; Pearson, Peter L. ; Zatz, Mayana ; Vainzof, Mariz . Genetic variability in the myostatin gene does not explain the muscle hypertrophy and clinical penetrance in myotonia congenita. Muscle & Nerve (Print) , v. 41, p. 427-428, 2010.

  • Lezirovitz, Karina ; Braga, MCC ; Thiele-Aguiar ; Auricchio ; PL Pearson ; Otto, P.A. ; Mingroni-Netto, R.C. . A novel autosomal dominant deafness locus (DFNA58) maps to 2p12-p21. Clinical Genetics , v. 75, p. 490-493, 2009.

  • Pearson, Peter . Tom Shows – King of the Mappers. Cytogenetic and Genome Research (Online) , v. 122, p. 1-4, 2008.

  • Lezirovitz, Karina ; Maestrelli, Sylvia Regina Pedrosa ; Cotrim, Nelson Henderson ; Otto, Paulo A. ; Pearson, Peter L. ; Mingroni-Netto, Regina Celia . A novel locus for split-hand/foot malformation associated with tibial hemimelia (SHFLD syndrome) maps to chromosome region 17p13.1 17p13.3. Human Genetics , v. 123, p. 625-631, 2008.

  • AMBROSIO, C ; VALADARES, M ; ZUCCONI, E ; CABRAL, R ; PEARSON, P ; GAIAD, T ; CANOVAS, M ; VAINZOF, M ; MIGLINO, M ; ZATZ, M . Ringo, a Golden Retriever Muscular Dystrophy (GRMD) dog with absent dystrophin but normal strength. Neuromuscular Disorders , v. 18, p. 892-893, 2008.

  • Hes, FJ ; van der Luijt, RB ; Janssen, ALW ; Zewald, RA ; de Jong, GJ ; Lenders, JW ; Links, TP ; Luyten, GPM ; Sijmons, RH ; Eussen, HJ ; Halley, DJJ ; Lips, CJM ; PEARSON, PL ; van den Ouweland, AMW ; Majoor-Krakauer, DF . Frequency of Von Hippel-Lindau germline mutations in classic and non-classic Von Hippel-Lindau disease identified by DNA sequencing, Southern blot analysis and multiplex ligation-dependent probe amplification. Clinical Genetics , v. 72, p. 122-129, 2007.

  • Bakker, S. C. ; Hoogendoorn, M. L. C. ; Hendriks, J. ; Verzijlbergen, K. ; Caron, S. ; Verduijn, W. ; Selten, J. P. ; Pearson, P. L. ; Kahn, R. S. ; Sinke, R. J. . The and genes are differentially associated with deficit and non-deficit schizophrenia. Genes, Brain and Behavior (Print) , v. 6, p. 113-119, 2007.

  • OGDIE, M N ; BAKKER, S C ; FISHER, S E ; FRANCKS, C ; YANG, M H ; CANTOR, R M ; LOO, S K ; MEULEN, E Van Der ; PEARSON, PL ; BUITELAAR, J ; MONACO, A ; NELSON, S F ; SINKE, R J ; SMALLEY, S L . Pooled genome-wide linkage data on 424 ADHD ASPs suggests genetic heterogeneity and a common risk locus at 5p13.. Molecular Psychiatry , v. 11, p. 5-8, 2006.

  • VAN ASSELT, K M ; KOK, H S ; VAN DER SCHOUW, Y T ; PEETERS, P H ; PEARSON, PL ; GROBBEE, D E . Role of genetic analyses in cardiology: part II: heritability estimation for gene searching in multifactorial diseases.. Circulation (New York) , v. 113, p. 1136-9, 2006.

  • KOK, H ; VANASSELT, K ; VANDERSCHOUW, Y ; VANDERTWEEL, I ; PEETERS, P ; WILSON, P ; PEARSON, PL ; GROBBEE, D . Heart Disease Risk Determines Menopausal Age Rather Than the Reverse. Journal of the American College of Cardiology (Print) , v. 47, p. 1976-1983, 2006.

  • Pearson, P.L. . Historical development of analysing large-scale changes in the human genome. Cytogenetic and Genome Research (Online) , v. 115, p. 198-204, 2006.

  • Krepischi-Santos, A.C.V. ; Vianna-Morgante, A.M. ; Jehee, F.S. ; Passos-Bueno, M.R. ; Knijnenburg, J. ; Szuhai, K. ; Sloos, W. ; Mazzeu, J.F. ; Kok, F. ; Cheroki, C. ; Otto, P.A. ; Mingroni-Netto, R.C. ; Varela, M. ; Koiffmann, C. ; Kim, C.A. ; Bertola, D.R. ; Pearson, P.L. ; Rosenberg, C. . Whole-genome array-CGH screening in undiagnosed syndromic patients: old syndromes revisited and new alterations. Cytogenetic and Genome Research (Online) , v. 115, p. 254-261, 2006.

  • BAKKER, S C ; VAN DER MEULEN, E M ; OTEMAN, N ; SCHELLEMAN, H ; PEARSON, PL ; BUITELAAR, J K ; SINKE, R J . DAT1, DRD4, and DRD5 polymorphisms are not associated with ADHD in Dutch families.. American Journal of Medical Genetics. Part B , v. 132, p. 50-2, 2005.

  • DE PAUW, E S ; ROELOFS, H ; ZWINDERMAN, A ; VAN HOUWELINGEN, J C ; FIBBE, W E ; DE KNIJFF, P ; PEARSON, PL ; TANKE, H J . Studying the biological and technical sources of variation in telomere length of individual chromosomes. Cytometry , v. 65, p. 35-9, 2005.

  • HOOGENDOORN, M L ; BAKKER, S C ; SCHNACK, H G ; SELTEN, J P ; OTTEN, H G ; VERDUIJN, W ; VAN DER HEIJDEN, F M ; PEARSON, PL ; KAHN, R S ; SINKE, R J . No association between 12 dopaminergic genes and schizophrenia in a large Dutch sample. American Journal of Medical Genetics. Part B , v. 134, p. 6-9, 2005.

  • PEARSON, PL . Patricia Ann Jacobs. Cytogenetic and Genome Research , v. 111, p. 97-100, 2005.

  • PEARSON, PL . Malcolm Ferguson-Smith. Cytogenetic and Genome Research , v. 111, p. 2-4, 2005.

  • RAMBAGS, B P ; KRIJTENBURG, P J ; DRIE, H F ; GALLI, C ; PEARSON, PL ; COLENBRANDER, B ; STOUT, T A ; LAZZARI, G . Numerical chromosomal abnormalities in equine embryos produced in vivo and in vitro. Molecular Reproduction and Development , v. 72, p. 77-87, 2005.

  • VAN DER MEULEN, E M ; BAKKER, S C ; PAULS, D L ; OTEMAN, N ; KRUITWAGEN, C L ; PEARSON, PL ; SINKE, R J ; BUITELAAR, J K . High sibling correlation on methylphenidate response but no association with DAT1-10R homozygosity in Dutch sibpairs with ADHD.. Journal of Child Psychology and Psychiatry and Allied Disciplines , v. 46, p. 1074-80, 2005.

  • BAKKER, S C ; HOOGENDORN, M L ; SELTEN, J P ; VERDUIJN, W ; PEARSON, PL ; SINKE, R J ; KAHN, R S . Neuregulin 1: genetic support for schizophrenia subtypes.. Molecular Psychiatry , v. 9, p. 1061-3, 2004.

  • BOERSMA-VREUGDENHIL, G R ; KUIPERS, J ; VAN STRALEN, E ; PEETERS, T ; MICHAUX, L ; HAGEMEIJER, A ; PEARSON, PL ; CLEVERS, H C ; BAST, B J . The recurrent translocation t(14;20)(q32;q12) in multiple myeloma results in aberrant expression of MAFB: a molecular and genetic analysis of the chromosomal breakpoint.. British Journal of Haematology , v. 126, p. 335-63, 2004.

  • KOK, H S ; VAN ASSELT, K M ; PEETERS, P H ; VAN DER SCHOUW, Y T ; GROBBEE, D E ; PEARSON, PL ; WIJMENGA, C . Age at natural menopause is not linked with the follicle-stimulating hormone receptor region: a sib-pair study.. Fertility and Sterility , v. 81, p. 611-6, 2004.

  • ROOS, Y B ; PALS, G ; STRUYCKEN, P M ; RINKEL, G J ; LIMBURG, M ; PRONK, J C ; VAN DER BERG, J S ; LUIJTEN, J A ; PEARSON, PL ; VERMEULEN, M ; TANKE, H J . Genome-wide linkage in a large Dutch consanguineous family maps a locus for intracranial aneurysms to chromosome 2p13. Stroke , v. 35, p. 2276-81, 2004.

  • SCHNACK, H G ; BAKKER, S C ; VAN´T SLOT, R ; GROOT, B M ; SINKE, R J ; KAHN, R S ; PEARSON, PL . Accurate determination of microsatellite allele frequencies in pooled DNA samples.. European Journal of Human Genetics , v. 12, p. 925-34, 2004.

  • VAN ASSELT, K M ; KOK, H S ; PEARSON, PL ; DUBAS, J S ; PEETERS, P H ; VELDE, E R ; VAN NOORD, P A . Heritability of menopausal age in mothers and daughters.. Fertility and Sterility , v. 82, p. 1348-51, 2004.

  • VAN ASSELT, K M ; KOK, H S ; VAN DER SCHOUW, Y T ; GROBBEE, D E ; VELDE, E R ; PEARSON, PL ; PEETERS, P H . Current smoking at menopause rather than duration determines the onset of natural menopause.. Epidemiology (Cambridge) , v. 15, p. 634-9, 2004.

  • VAN ASSELT, K M ; KOK, H S ; PUTTER, H ; WIJMENGA, C ; PEETERS, P H ; VAN DER SCHOUW, Y T ; GROBBEE, D E ; VELDE, E R ; MOSSELMAN, S ; PEARSON, PL . Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative trait loci influencing variation in human menopausal age. American Journal of Human Genetics , v. 74, p. 444-53, 2004.

  • VAN BELZEN, M J ; KOELEMAN, B P ; CRUSIUS, J B ; MEIJER, J W ; BARDOEL, A F ; PEARSON, PL . Defining the contribution of the HLA region to cis DQ2-positive coeliac disease patients.. Genes and Immunity , v. 5, p. 215-20, 2004.

  • VAN BELZEN, M J ; VROLIJIK, M M ; CRUSIUS, J B ; PEARSON, PL ; SANDKUIJL, L A ; HOUWEN, R H ; WIJMENGA, C . A genomewide screen in a four-generation Dutch family with celiac disease: evidence for linkage to chromosomes 6 and 9. American Journal of Gastroenterology , v. 99, p. 466-71, 2004.

  • VAN BELZEN, M J ; MULDER, C J ; ZHERNAKOVA, A ; PEARSON, PL ; HOUWEN, R H ; WIJMENGA, C . CTLA4 +49 A/G and CT60 polymorphisms in Dutch coeliac disease patients.. European Journal of Human Genetics , v. 12, p. 782-5, 2004.

  • VERBEEK, D S ; PIERSMA, S J ; HENNEKAM, E F ; IPPEL, E F ; PEARSON, PL ; SINKE, R J . Haplotype study in Dutch SCA3 and SCA6 families: evidence for common founder mutations.. European Journal of Human Genetics , v. 12, p. 441-6, 2004.

  • VERBEEK, D S ; WESSELING, P ; PEARSON, PL ; KREMER, H P ; SINKE, R J ; VAN DE WARRENBURG, B P . Mapping of the SCA23 locus involved in autosomal dominant cerebellar ataxia to chromosome region 20p13-12.3.. Brain (London) , v. 127, p. 2551-7, 2004.

  • BAKKER, S C ; VAN DER MEULEN, E M ; BUITELAAR, J K ; SANDKUIJL, L A ; PAULS, D L ; MONSUUR, A J ; VAN´T SLOT, R ; MINDERAA, R B ; GUNNING, W B ; PEARSON, PL ; SINKE, R J . A whole-genome scan in 164 Dutch sib pairs with attention-deficit/hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15q. American Journal of Human Genetics , v. 72, p. 1251-60, 2003.

  • BEVERSTOCK, G C ; BEZROOKOVE, V ; MOLLEVANGER, P ; VAN DE KAMP, J J ; PEARSON, PL ; KOUWENBERG, J M ; ROSENBERG, C . Multiple supernumerary ring chromosomes of different origin in a patient: a clinical report and review of the literature. American Journal of Medical Genetics , v. 122A, p. 168-73, 2003.

  • STRUYCKEN, P M ; PALS, G ; LIMBURG, M ; PRONK, J C ; WIJMENGA, C ; PEARSON, PL ; LUIJTEN, J A ; VAN DER BERG, J S ; VERMEULEN, M ; RINKEL, G J ; WESTERVELD, A . Anticipation in familial intracranial aneurysms in consecutive generations.. European Journal of Human Genetics , v. 11, p. 737-43, 2003.

  • KOK, H S ; VAN ASSELT, K M ; VAN DER SCHOUW, Y T ; GROBBEE, D E ; VELDE, E R ; PEARSON, PL ; PEETERS, P H . Subfertility reflects accelerated ovarian ageing.. Human Reproduction , v. 18, p. 644-8, 2003.

  • VAN ASSELT, K M ; KOK, H S ; PEETERS, P H ; ROEST, M ; PEARSON, PL ; VELDE, E R ; GROBBEE, D E ; VAN DER SCHOUW, Y T . Factor V Leiden mutation accelerates the onset of natural menopause.. Menopause, v. 10, p. 477-81, 2003.

  • VAN BELZEN, M J ; MEIJER, J W ; SANDKUIJL, L A ; BARDOEL, A F ; MULDER, C J ; PEARSON, PL ; HOUWEN, R H ; WIJMENGA, C . A major non-HLA locus in celiac disease maps to chromosome 19.. Gastroenterology (New York) , v. 125, p. 1032-41, 2003.

  • VAN DE WARRENBURG, B P ; VERBEEK, D S ; PIERSMA, S J ; HENNEKAM, F A ; PEARSON, PL ; KNOERS, N V ; KREMER, H P ; SINKE, R J . Identification of a novel SCA14 mutation in a Dutch autosomal dominant cerebellar ataxia family. Neurology (Cleveland, Ohio) , v. 61, p. 1760-5, 2003.

  • VAN DER HEL, O L ; BUENO DE MESQUITA, H B ; SANDKUIJL, L A ; VAN NOORD, P A ; PEARSON, PL ; GROBBEE, D E ; PEETERS, P H . Rapid N-acetyltransferase 2 imputed phenotype and smoking may increase risk of colorectal cancer in women (Netherlands). CCC. Cancer Causes & Control , v. 14, p. 293-8, 2003.

  • VAN TILBURG, J H ; SANDKUIJL, L A ; STRENGMAN, E ; PEARSON, PL ; VAN HAEFTEN, T W ; WIJMENGA, C . Variance-component analysis of obesity in type 2 diabetes confirms loci on chromosomes 1q and 11q.. Obesity Research , v. 11, p. 1290-4, 2003.

  • VAN TILBURG, J H ; SANDKUIJL, L A ; FRANKE, L ; STRENGMAN, E ; PEARSON, PL ; VAN HAEFTEN, T W ; WIJMENGA, C . Genome-wide screen in obese pedigrees with type 2 diabetes mellitus from a defined Dutch population.. European Journal of Clinical Investigation , v. 33, p. 1070-4, 2003.

  • VAN TILBURG, J H ; WIJMENGA, C ; VAN BAKEL, H ; ROZEMAN, L ; PEARSON, PL ; VAN HAEFTEN, T W . Relationship of beta2-adrenergic receptor polymorphism with obesity in type 2 diabetes.. Diabetes Care , v. 26, p. 251-2, 2003.

  • VAN TILBURG, J H ; SANDKUIJL, L A ; STRENGMAN, E ; VAN SOMEREN, H ; RIGTERS ARIS, C A ; PEARSON, PL ; VAN HAEFTEN, T W ; WIJMENGA, C . A genome-wide scan in type 2 diabetes mellitus provides independent replication of a susceptibility locus on 18p11 and suggests the existence of novel Loci on 2q12 and 19q13. The Journal of Clinical Endocrinology and Metabolism , v. 88, p. 2223-30, 2003.

  • ROSENBERG, C ; GEELEN, E ; IJSZENGA, M J ; PEARSON, PL ; TANKE, H J ; DINJENS, W N ; VAN DEKKEN, H . Spectrum of genetic changes in gastro-esophageal cancer cell lines determined by an integrated molecular cytogenetic approach.. Cancer Genetics and Cytogenetics , v. 135, p. 35-41, 2002.

  • TE VELDE, E R ; PEARSON, PL . The variability of female reproductive ageing.. Human Reproduction Update , v. 8, p. 141-54, 2002.

  • VAN DE, S B ; ROTHUIZEN, J ; PEARSON, PL ; VAN OOST, B A ; WIJMENGA, C . Identification of a new copper metabolism gene by positional cloning in a purebred dog population.. Human Molecular Genetics , v. 11, p. 165-73, 2002.

  • VAN DER HEL, O L ; VAN DER LUIJT, R B ; BUENO DE MESQUITA, H B ; VAN NOORD, P A ; SLOTHOUBER, B ; VAN DER SCHOUW, Y T ; GROBBEE, D E ; PEARSON, PL ; PEETERS, P H . Quality and quantity of DNA isolated from frozen urine in population-based research.. Analytical Biochemistry , v. 304, p. 206-11, 2002.

  • VERBEEK, D S ; SCHELHAAS, J H ; IPPEL, E F ; BEEMER, F A ; PEARSON, PL ; SINKE, R J . Identification of a novel SCA locus ( SCA19) in a Dutch autosomal dominant cerebellar ataxia family on chromosome region 1p21-q21.. Human Genetics , v. 111, p. 388-93, 2002.

  • BUIJS, A ; PODDIGHE, P ; VAN WINK, R ; VAN SOLINGE, W ; BORST, E ; VERDONCK, L ; HAGENBEEK, A ; PEARSON, PL ; LOKHORST, H . A novel CBFA2 single-nucleotide mutation in familial platelet disorder with propensity to develop myeloid malignancies.. Blood (Philadelphia) , v. 98, p. 2856-8, 2001.

  • DE BRUIN, J P ; BOVENHUIS, H ; VAN NOORD, P A ; PEARSON, PL ; VAN ARENDONK, J A ; VELDE, E R ; KUURMAN, W W ; DORLAND, M . The role of genetic factors in age at natural menopause. Human Reproduction , v. 16, p. 2014-8, 2001.

  • PEARSON, PL ; TE VELDE, E R . The social behavioural and genetic determinants of female infertility.. Tijdschrift Voor Fertiliteitsonderzoek, v. 15, p. 2-7, 2001.

  • ROSENBERG, C ; WOUTERS, C H ; SZUHAI, K ; DORLAND, R ; PEARSON, PL ; POLL-THE, B T ; COLOMBIJN, R M ; BREUNING, M ; LINDHOUT, D . A Rett syndrome patient with a ring X chromosome: further evidence for skewing of X inactivation and heterogeneity in the aetiology of the disease.. European Journal of Human Genetics , v. 9, p. 171-7, 2001.

  • VAN BELZEN, M J ; MULDER, C J ; PEARSON, PL ; HOUWEN, R H ; WIJMENGA, C . The tissue transglutaminase gene is not a primary factor predisposing to celiac disease. American Journal of Gastroenterology , v. 96, p. 3337-40, 2001.

  • VAN DE, S B ; NANJI, M S ; BREEN, M ; PEARSON, PL ; OOST, B A ; COX, D W ; WIJMENGA, C . Characterization and chromosomal localization of five canine ATOX1 pseudogenes.. Cytogenetics and Cell Genetics , v. 93, p. 105-8, 2001.

  • VAN TILBURG, J H ; VAN HAEFTEN, T W ; PEARSON, PL ; WIJMENGA, C . Defining the genetic contribution of type 2 diabetes mellitus.. Journal of Medical Genetics , v. 38, p. 569-78, 2001.

  • VAN TILBURG, J H ; STRENGMAN, E ; PEARSON, PL ; SOMMEREN, H . Are genes on chromosome 20 involved in type 2 diabetes mellitus in the Netherlands?. Netherlands Journal of Medicine , v. 59, p. A1-A7, 2001.

  • HACKSTEIN, J H ; HOCHSTENBACH, R ; PEARSON, PL . Towards an understanding of the genetics of human male infertility: lessons from flies.. Trends in Genetics , v. 16, p. 565-72, 2000.

  • HES, F ; ZEWALD, R ; PEETERS, T ; SIJMONS, R ; LINKS, T ; VERHEIJ, J ; MATTHIJS, G ; LEGUIS, E ; MORTIER, G ; VAN DER TORREN, K ; ROSMAN, M ; LIPS, C ; PEARSON, PL ; VAN DER LUIJT, R . Genotype-phenotype correlations in families with deletions in the von Hippel-Lindau (VHL) gene.. Human Genetics , v. 106, p. 425-31, 2000.

  • HES, F ; MCKEE, S ; TAPHOORN, M J ; REHAL, P ; VAN DER LUIJT, R B ; MCMAHON, R ; VAN DER SMAGT, J J ; DOW, D ; ZEWALD, R A ; WHITTAKER, J ; LIPS, C J ; MACDONALD, F ; PEARSON, PL ; MAHER, e R . Cryptic von Hippel-Lindau disease: germline mutations in patients with haemangioblastoma only.. Journal of Medical Genetics , v. 37, p. 939-43, 2000.

  • PEARSON, PL . Chromosomen en DNA: alles wat u al weten wilde en nooit durfde te vragen. Infertiliteit, gynaecologie en obstetrie anno 2000.. Organon Nederland, p. 30-3, 2000.

  • VAN DE SLUIS, B ; KOLE, S ; VAN WOLFEREN, M ; HOLMES, N G ; PEARSON, PL ; ROTHUIZEN, J ; VAN OOST, B A ; WIJMENGA, C . Refined genetic and comparative physical mapping of the canine copper toxicosis locus.. Mammalian Genome , v. 11, p. 455-60, 2000.

  • VAN TILBURG, J H ; ROZEMAN, L B ; VAN SOMEREN, H ; RIGTERS ARIS, C A ; FRERIKS, J P ; PEARSON, PL ; SANDKUIJL, L A ; VAN HAEFTEN, T W ; WIJMENGA, C . The exon 16-3t variant of the sulphonylurea receptor gene is not a risk factor for Type II diabetes mellitus in the Dutch Breda cohort.. Diabetologia (Berlin) , v. 43, p. 681-2, 2000.

  • WIJMENGA, C ; HANSEN, R S ; GIMELLI, G ; BJORCK, e J ; DAVIES, e G ; VALENTINE, D ; BELOHRADSKY, B H ; VAN DEN HEUVEL, J J ; LUYTEN, J A ; STRENGMAN, E ; WEEMAES, C ; PEARSON, PL . Genetic variation in ICF syndrome: evidence for genetic heterogeneity.. Human Mutation , v. 16, p. 509-17, 2000.

  • GILTAY, J C ; KASTROP, P M ; TIEMESSEN, C H ; VAN INZEN, W G ; SCHERES, J M ; PEARSON, PL . Sperm analysis in a subfertile male with a Y;16 translocation, using four-color FISH.. Cytogenetics and Cell Genetics , v. 84, p. 67-72, 1999.

  • HES, F J ; SLOOTWEG, P J ; VAN VROONHOVEN, T J ; HENE, R J ; FELDBERG, M A ; ZEWALD, R A ; PLOOS VAN AMSTEL, J K ; HOPPENER, J W ; PEARSON, PL ; LIPS, C J . Management of renal cell carcinoma in von Hippel-Lindau disease.. European Journal of Clinical Investigation , v. 29, p. 68-75, 1999.

  • KUIPERES, J ; VAANDRAGER, J W ; WEGHUIS, D O ; PEARSON, PL ; SCHERES, J ; LOKHORST, H M ; CLEVERS, H ; BAST, B J . Fluorescence in situ hybridization analysis shows the frequent occurrence of 14q32.3 rearrangements with involvement of immunoglobulin switch regions in myeloma cell lines.. Cancer Genetics and Cytogenetics , v. 109, p. 99-107, 1999.

  • MULLER, T ; VAN DE SLUIS, B ; MULLER, W ; PEARSON, PL ; WIJMENGA, C . Non-Indian childhood cirrhosis.. European Journal of Medical Research , v. 4, p. 293-7, 1999.

  • SCHERES, J M ; DE PATER, J M ; STOUTENBEEK, P ; WIJMENGA, C ; ROSENBERG, C ; PEARSON, PL . Isochromosome 1q as the sole chromosomal abnormality in two fetal teratomas. Possible trisomic or tetrasomic zygote rescue in fetal teratoma with an additional isochromosome 1q. Cancer Genetics and Cytogenetics , v. 115, p. 1-10, 1999.

  • VAN DE SLUIS, B ; BREEN, M ; NANJI, M ; VAN WOLFEREN, M ; JONG, P de ; BINNS, M M ; PEARSON, PL ; KUIPERS, J ; ROTHUIZEN, J ; COX, D W ; WIJMENGA, C ; VAN OOST, B A . Genetic mapping of the copper toxicosis locus in Bedlington terriers to dog chromosome 10, in a region syntenic to human chromosome region 2p13-p16.. Human Molecular Genetics , v. 8, p. 501-7, 1999.

  • SCHERES, J ; DE PATER, J M ; WIJMENGA, C ; STOUTENBEEK, P ; PEARSON, PL . Foetaal teratoma met extra isochromosoom 1q: een onverwacht onstaansmechanisme.. Nederlands Tijdschrift Voor Obstetrie Gynaecologie, p. 112, 1999.

  • GILTAY, J C ; BRUNT, T ; BEEMER, F A ; WIT, J M ; VAN AMSTEL, H K ; PEARSON, PL ; WIJMENGA, C . Polymorphic detection of a parthenogenetic maternal and double paternal contribution to a 46,XX/46,XY hermaphrodite.. American Journal of Human Genetics , v. 62, p. 937-40, 1998.

  • PEARSON, PL ; VAN DER LUIJT, R B . The genetic analysis of cancer.. Journal of Internal Medicine , v. 243, p. 413-7, 1998.

  • PEARSON, PL . Insights into the structure and function of genetic diseases from genome research and clues for drug therapy.. Trends In Drug Research Elsevier Science Bv, p. 1-6, 1998.

  • WIJMENGA, C ; HEUVEL, L P Van Den ; STRENGMAN, E ; LUYTEN, J A ; BURGT, I J Van Der ; GROOT, R de ; SMEETS, D F ; DRAAISMA, J M ; DONGEN, J J Van ; ABREU, R A de ; PEARSON, PL ; SANDKUIJL, L A ; WEEMAES, C M . Localization of the ICF syndrome to chromosome 20 by homozygosity mapping.. American Journal of Human Genetics , v. 63, p. 803-9, 1998.

  • WIJMENGA, C ; MULLER, T ; MURLI, I S ; BRUNT, T ; FEICHTINGER, H ; SCHONITZER, D ; HOUWEN, R H ; MULLER, W ; SANDKUIJL, L A ; PEARSON, PL . Endemic Tyrolean infantile cirrhosis is not an allelic variant of Wilson's disease.. European Journal of Human Genetics , v. 6, p. 624-8, 1998.

  • VELD, Pa In´t ; BROEKMANS, F J ; DE FRANCE, H F ; PEARSON, PL ; PIETERS, M H ; VAN KOOIJ, R J . Intracytoplasmic sperm injection (ICSI) and chromosomally abnormal spermatozoa.. Human Reproduction , v. 12, p. 752-4, 1997.

  • SINKE, R J ; CARLTON, VE ; JUIJN, J A ; DELHAAS, T ; BULL, L ; VAN BERGEL HENEGOUWEN, G P ; VAN HATTUM, J ; KELLER, K M ; SINAASAPPEL, M ; BIJLEVELD, C M ; KNOL, I E ; PLOOS VAN AMSTEL, H K ; PEARSON, PL ; BERGER, R ; FREIMER, N B ; HOWEN, R H . Benign recurrent intrahepatic cholestasis (BRIC): evidence of genetic heterogeneity and delimitation of the BRIC locus to a 7-cM interval between D18S69 and D18S64.. Human Genetics , v. 100, p. 382-7, 1997.

  • ZWAMBORN-HANSSEN, A M ; BIJLSMA, J B ; HENNEKAM, E F ; PEARSON, PL . The Dutch Uniform Multicenter Registration system for genetic disorders and malformation syndromes.. American Journal of Medical Genetics , v. 70, p. 444-7, 1997.

  • WHITE, J A ; ANTONARAKIS, S ; CANN, H ; EPPIG, J T ; FRAZER, K ; FREZAL, J ; LANCET, D ; NAHMIAS, J ; PEARSON, PL ; PETERS, J ; SCOTT, A ; SPURR, N ; TALBOT, C ; POVEY, S . Guidelines for human gene nomenclature (1997). HUGO Nomenclature Committee.. Genomics (San Diego) , v. 45, p. 468-71, 1997.

  • FENCHER, P Y ; ROSENBERG, C ; STETTEN, G ; CARGILE, C B ; PEARSON, PL ; SMITH, K D ; MIGEON, C J ; BERKOVITZ, G D . Nonrandom inactivation of the Y-bearing X chromosome in a 46,XX individual: evidence for the etiology of 46,XX true hermaphroditism.. Cytogenetics and Cell Genetics , v. 66, p. 22-6, 1994.

  • KEARNS, W G ; PEARSON, PL . Detection of chromosomal aberrations in interphase and metaphase cells in prenatal and postnatal studies.. Methods in Molecular Biology (Clifton) , v. 33, p. 459-76, 1994.

  • KEARNS, W G ; PEARSON, PL . Fluorescent in situ hybridization using chromosome-specific DNA libraries.. Methods in Molecular Biology (Clifton) , v. 33, p. 15-22, 1994.

  • PEARSON, PL ; FRANCOMANO, C ; FOSTER, P ; BOCCHINI, C ; LI, P ; MCKUSICK, V . The status of online Mendelian inheritance in man (OMIM) medio 1994. Nucleic Acids Research , v. 22, p. 3470-3, 1994.

  • BATISTA, D A ; TUCK-MULLER, C M ; MARTINEZ, J e ; KEARNS, W G ; PEARSON, PL ; SETTEN, G . A complex chromosomal rearrangement detected prenatally and studied by fluorescence in situ hybridization.. Human Genetics , v. 92, p. 117-21, 1993.

  • BLACKMORE, K J ; ROSENBERG, C ; JASWANEY, V L ; PEARSON, PL . Rapid diagnosis of trisomy 18 and dizygosity in twins using fluorescen in situ hybridization on uncultured amniocytes.. J Maternal Fetal Medicine, v. 2, p. 197-200, 1993.

  • CUTICCHIA, A J ; FASMAN, K H ; KINGSBURY, D T ; ROBBINS, R J ; PEARSON, PL . The GDB human genome data base anno 1993.. Nucleic Acids Research , v. 21, p. 3003-6, 1993.

  • CUTICCHIA, A J ; CHIPPERFIELD, M A ; PORTES, C J ; KEARNS, W G ; PEARSON, PL . Managing all those bytes: the Human Genome Project.. Science , v. 262, p. 47-8, 1993.

  • GARTNER, J ; KEARNS, W G ; ROSENBERG, C ; PEARSON, PL ; COPELAND, N G ; GILBERT, D J ; JENKINS, N A ; VALLE, D . Localization of the 70-kDa peroxisomal membrane protein to human 1p21-p22 and mouse 3.. Genomics (San Diego) , v. 15, p. 412-4, 1993.

  • GERAGHTY, M T ; BRODY, L C ; MARTIN, L S ; MARBLE, M ; KEARNS, W ; PEARSON, PL ; MONACO, A P ; LEHRACH, H ; VALLE, D . The isolation of cDNAs from OATL1 at Xp 11.2 using a 480-kb YAC.. Genomics (San Diego) , v. 16, p. 440-6, 1993.

  • GERAGHTY, M T ; KEARNS, W G ; PEARSON, PL ; VALLE, D . Isolation and characterization of an ornithine aminotransferase-related sequence (OATL3) mapping to 10q26.. Genomics (San Diego) , v. 17, p. 510-3, 1993.

  • LAMB, B T ; SISODIA, S S ; LAWLER, A M ; SLUNT, H H ; KITT, C A ; KEARNS, W G ; PEARSON, PL ; PRICE, D L ; GEARHART, J D . Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected].. Nature Genetics , v. 5, p. 22-30, 1993.

  • MCGINNISS, M J ; ROSENBERG, C ; SETTEN, G ; SCHINZEL, A A ; BINKERT, F ; PETERSEN, M B ; KEARNS, W G ; KAZAZIAN, H H ; PEARSON, PL ; ANTONARAKIS, S E . Unbalanced translocation, t(18;21), detected by fluorescence in situ hybridization (FISH) in a child with 18q- syndrome and a ring chromosome 21.. American Journal of Medical Genetics , v. 46, p. 647-51, 1993.

  • MIGEON, B R ; MCGINNISS, M J ; ANTONARAKIS, S E ; AXELMAN, J ; STASIOWSKI, B A ; YOUSSOUFIAN, H ; KEARNS, W G ; CHUNG, A ; PEARSON, PL ; KAZAZIAN, H H ; MUNEER, R S . Severe hemophilia A in a female by cryptic translocation: order and orientation of factor VIII within Xq28.. Genomics (San Diego) , v. 16, p. 20-5, 1993.

  • PEARSON, PL ; MATHESON, N W ; FLESCHER, D C ; ROBBINS, R J . The GDB Human Genome Data Base Anno 1992.. Nucleic Acids Research (Online) , v. 20, p. 2201-6, 1992.

  • ROSENBERG, C ; BLACKMORE, K J ; KEARNS, W G ; GIRALDEZ, R A ; ESCALLON, C S ; PEARSON, PL ; STETTEN, G . Analysis of reciprocal translocations by chromosome painting: applications and limitations of the technique.. American Journal of Human Genetics , v. 50, p. 700-5, 1992.

  • MANDEL, J L ; MONACO, A P ; NELSON, D L ; SCHLESSINGER, D ; WILLARD, H F ; CHIPPERFIELD, M ; PEARSON, PL ; P, Gilna ; CINKOSKY, M . Genome maps III. 1992. Wall Chart.. Science , v. 258, p. 87-102, 1992.

  • CHIPPERFIELD, M ; MAIDEK, M ; PEARSON, PL . Genome maps 1991 [wall chart].. Science , v. 254, p. 247-62, 1991.

  • DEVILEE, P ; VAN VILET, M ; BARDOEL, A ; KIEVITS, T ; KUIPERS-DIJKSHOORN, N ; PEARSON, PL ; CORNELISSE, C J . Frequent somatic imbalance of marker alleles for chromosome 1 in human primary breast carcinoma.. Cancer Research , v. 51, p. 1020-5, 1991.

  • DEVILEE, P ; VAN VILET, M ; KUIPERS-DIJKSHOORN, N ; PEARSON, PL ; CORNELISSE, C J . Somatic genetic changes on chromosome 18 in breast carcinomas: is the DCC gene involved?. Oncogene (Basingstoke) , v. 6, p. 311-5, 1991.

  • DEVILEE, P ; VAN VLIET, M ; VAN SLOUN, P ; KUIPERS-DIJKSHOORN, N ; HERMANS, J ; PEARSON, PL ; CORNELISSE, C J . Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q.. Oncogene (Basingstoke) , v. 6, p. 1705-11, 1991.

  • PEARSON, PL . Genome mapping databases: data acquisition, storage and access.. Current Opinion in Genetics & Development , v. 1, p. 119-23, 1991.

  • PEARSON, PL ; MAIDAK, B ; CHIPPERFIELD, M ; ROBBINS, R . The human genome initiative-do databases reflect current progress?. Science , v. 254, p. 214-5, 1991.

  • PEARSON, PL . The genome data base (GDB)-a human gene mapping repository.. Nucleic Acids Research , v. 19, p. 2237-9, 1991.

  • ROSENBERG, C ; STETTEN, G ; KEARNS, W G ; PEARSON, PL ; LITTLEFIELD, J W . Origin of chromosome rearrangements in two long-lived human keratinocyte lines.. In Vitro Cellular Developmental Biology , v. 27A, p. 823-5, 1991.

  • SKAASTAD, M I ; VERWEST, A ; BAKKER, E ; Vegter-van Der VLIS, M ; LEEUWEN-CORNELISSE, I Van ; ROOS, R A ; PEARSON, PL ; VAN OMMEN, G J . Presymptomatic, prenatal, and exclusion testing for Huntington disease using seven closely linked DNA markers.. American Journal of Medical Genetics , v. 39, p. 217-22, 1991.

  • BREUNING, M H ; SNIJDEWINT, F G ; DAUWERSE, J G ; SARIS, J J ; BAKKER, E ; PEARSON, PL ; VAN OMMEN, G J . Two step procedure for early diagnosis of polycystic kidney disease with polymorphic DNA markers on both sides of the gene.. American Journal of Medical Genetics , v. 27, p. 614-7, 1990.

  • BROCKER-VRIENDS, A H ; BRIET, E ; DREESEN, J C ; BAKKER, B ; REITSMA, P ; PANNEKOEK, H ; VAN DE KAMP, J J ; PEARSON, PL . Somatic origin of inherited haemophilia A.. Human Genetics , v. 85, p. 288-92, 1990.

  • DAUWERSE, J G ; KIEVITS, T ; BEVERSTOCK, G C ; KEUR, D Van Der ; SMIT, e ; WESSELS, H W ; HAGEMEIJER, A ; PEARSON, PL ; VAN OMMEN, G J ; BREUNING, M H . Rapid detection of chromosome 16 inversion in acute nonlymphocytic leukemia, subtype M4: regional localization of the breakpoint in 16p.. Cytogenetics and Cell Genetics , v. 53, p. 126-8, 1990.

  • DEVILEE, P ; CORNELISSE, C J ; KUIPERS-DIJKSHOORN, N ; JONKER, C ; PEARSON, PL . Loss of heterozygosity on 17p in human breast carcinomas: defining the smallest common region of deletion.. Cytogenetics and Cell Genetics , v. 53, p. 52-54, 1990.

  • KIEVITS, T ; DEVILEE, P ; WIEGANT, J ; WAPENAAR, M C ; CORNELISSE, C J ; VAN OMMEN, G J ; PEARSON, PL . Direct nonradioactive in situ hybridization of somatic cell hybrid DNA to human lymphocyte chromosomes.. Cytometry , v. 11, p. 105-9, 1990.

  • PEARSON, PL . Rapid subchromosomal localization of cosmids by nonradioactive in situ hybridization.. Cytogenetics and Cell Genetics , v. 53, p. 134-6, 1990.

  • PEARSON, PL ; WAPENAAR, M C ; VAN OMMEN, G J . P9 (DXYS75) detects a VNTR-type RFLP in the pseudoautosomal region.. Nucleic Acids Research , v. 18, p. 384, 1990.

  • WAPENAAR, M C ; KIEVITS, T ; MEERA KHAN, P ; PEARSON, PL ; VAN OMMEN, G J . Isolation and characterization of cell hybrids containing human Xp-chromosome fragments.. Cytogenetics and Cell Genetics , v. 54, p. 10-4, 1990.

  • WILLIAMSON, R ; BOWCOCK, A ; KIDD, K ; PEARSON, PL ; SCHMIDTKE, J ; CHAN, H S ; CHIPPERFIELD, M ; COOPER, D N ; HEWITT, J ; LEWITTER, F . Report of the DNA committee and catalogues of cloned and mapped genes and DNA polymorphisms.. Cytogenetics and Cell Genetics , v. 55, p. 457-778, 1990.

  • PEARSON, PL . [Procedure and initial results of presymptomatic DNA studies in Huntington's chorea].. Nederlands Tijdschrift Voor Geneeskunde , v. 134, p. 704-7, 1990.

  • BAKKER, E ; VEENEMA, H ; DEN DUNNEN, J T ; VAN BROECKHOVEN, C ; GROOTSCHOLTEN, P M ; BONTEN, E J ; VAN OMMEN, G J ; PEARSON, PL . Germinal mosaicism increases the recurrence risk for 'new'Duchenne muscular dystrophy mutations.. American Journal of Medical Genetics , v. 26, p. 553-9, 1989.

  • BAKKER, E ; BONTEN, E J ; VEENEMA, H ; DEN DUNNEN, J T ; GROOTSCHOLTEN, P M ; VAN OMMEN, G J ; PEARSON, PL . Prenatal diagnosis of Duchenne muscular dystrophy: a three-year experience in a rapidly evolving field.. Journal of Inherited Metabolic Disease , v. 12, p. 74-90, 1989.

  • BAKKER, E ; BONTEN, E J ; DEN DUNNEN, J T ; VEENEMA, H ; GROOTSCHOLTEN, P M ; VAN OMMEN, G J ; PEARSON, PL . Carrier detection and prenatal diagnosis of Duchenne/Becker muscular dystrophy (D/BMD) by DNA-analysis.. Prog Clin Biol Res , v. 306, p. 51-67, 1989.

  • BLONDEN, L A ; DEN DUNNEN, J T ; PAASSEN, H M Van ; WAPENAAR, M C ; GROOTSCHOLTEN, P P ; GINJAAR, H B ; BAKKER, E ; PEARSON, PL ; VAN OMMEN, G J . High resolution deletion breakpoint mapping in the DMD gene by whole cosmid hybridization.. Nucleic Acids Research , v. 17, p. 5611-21, 1989.

  • BREUNING, M H ; VERWEST, A ; IJDO, J ; SARIS, J J ; KEITH, T ; REEDERS, S T ; VAN OMMEN, G J ; PEARSON, PL . Characterization of new probes for diagnosis of polycystic kidney disease (PKD1).. Prog Clin Biol Res , v. 305, p. 69-75, 1989.

  • BREUNING, M H ; DAUWERSE, J G ; SARIS, J J ; VAN OMMEN, G J ; PEARSON, PL . RFLP for an anonymous single copy clone at 16pter-16p13.1 [D16S127].. Nucleic Acids Research , v. 17, p. 5872, 1989.

  • PEARSON, PL . Cosmid vector pCpG and plasmid vector pKNUN1, and their use for cloning DNA sequences adjacent to sites for rare cutting restriction endonucleases.. Nucleic Acids Research , v. 17, p. 3603, 1989.

  • DEN DUNNEN, J T ; GROOTSCHOLTEN, P M ; BAKKER, E ; BLONDEN, L A ; GINJAAR, H B ; WAPENAAR, M C ; PAASSEN, H M Van ; VAN BROECKHOVEN, C ; PEARSON, PL ; VAN OMMEN, G J . Topography of the Duchenne muscular dystrophy (DMD) gene: FIGE and cDNA analysis of 194 cases reveals 115 deletions and 13 duplications.. American Journal of Human Genetics , v. 45, p. 835-47, 1989.

  • DEN DUNNEN, J T ; BAKKER, E ; VAN OMMEN, G J ; PEARSON, PL . The DMD gene analysed by field inversion gel electrophoresis.. British Medical Bulletin , v. 45, p. 644-58, 1989.

  • DEVILEE, P ; BROEK, M Van Den ; KUIPERS-DIJKSHOORN, N ; KOLLURI, R ; KHAN, P M ; PEARSON, PL ; CORNELISSE, C J . At least four different chromosomal regions are involved in loss of heterozygosity in human breast carcinoma.. Genomics (San Diego) , v. 5, p. 554-60, 1989.

  • KID, K K ; BOWCOCK, A M ; SCHIMIDTKE, J ; TRACK, R K ; RICCIUTI, F ; HUTCHINGS, G ; BALE, A ; PEARSON, PL ; WILLARD, H F ; GELERNTER, J . Report of the DNA committee and catalogs of cloned and mapped genes and DNA polymorphisms.. Cytogenetics and Cell Genetics , v. 51, p. 622-947, 1989.

  • SKRAASTAD, M I ; BAKKER, E ; LANGE, L F de ; Vegter-van Der VLIS, M ; KLEIN-BRETELER, Eg ; VAN OMMEN, G J ; PEARSON, PL . Mapping of recombinants near the Huntington disease locus by using G8 (D4S10) and newly isolated markers in the D4S10 region.. American Journal of Human Genetics , v. 44, p. 560-6, 1989.

  • VAN OMMEN, G J ; PEARSON, PL . Long-range mapping in the research and diagnosis of genetic disease.. Genome (Ottawa) , v. 31, p. 730-6, 1989.

  • ARVEILER, B ; OBERLE, I ; VINCENT, A ; HOFKER, M H ; PEARSON, PL ; MANDEL, J L . Genetic mapping of the Xq27-q28 region: new RFLP markers useful for diagnostic applications in fragile-X and hemophilia-B families.. American Journal of Human Genetics , v. 42, p. 380-9, 1988.

  • BROCKER-VRIENDS, A H ; BRIET, E ; KANHAI, H H ; BAKKER, E ; DREESEN, J C ; LESCHOT, N J ; VAN DE KAMP, J J ; PEARSON, PL . First trimester prenatal diagnosis of haemophilia A: two years'experience.. Prenatal Diagnosis , v. 8, p. 411-21, 1988.

  • CREMERS, F P ; VAN DE POL, T J ; WIERINGA, B ; HOFKER, M H ; PEARSON, PL ; PFEIFFER, R A ; MIKKELSEN, M ; TABOR, A ; ROOPERS, H H . Molecular analysis of male-viable deletions and duplications allows ordering of 52 DNA probes on proximal Xq.. American Journal of Human Genetics , v. 43, p. 452-61, 1988.

  • DEVILEE, P ; KIEVITS, T ; WAYE, J S ; PEARSON, PL ; WILLARD, H F . Chromosome-specific alpha satellite DNA: isolation and mapping of a polymorphic alphoid repeat from human chromosome 10.. Genomics (San Diego) , v. 3, p. 1-7, 1988.

  • DEVILEE, P ; THIERRY, R F ; KIEVITS, T ; KOLLURI, R ; HOPMAN, A H ; WILLARD, H F ; PEARSON, PL ; CORNELISSE, C J . Detection of chromosome aneuploidy in interphase nuclei from human primary breast tumors using chromosome-specific repetitive DNA probes.. Cancer Research , v. 48, p. 5825-30, 1988.

  • KID, K K ; BOWCOCK, A M ; PEARSON, PL ; SCHMIDTKE, J ; WILLARD, H F ; TRACK, R K ; RICCIUTI, F . Report of the committee on human gene mapping by recombinant DNA techniques.. Cytogenetics and Cell Genetics , v. 49, p. 132-218, 1988.

  • MANNENS, M ; SLATER, R M ; HEYTING, C ; BLIEK, J ; KRAKER, J de ; COAD, N ; PAGTER-HOLTHUIZEN, P ; PEARSON, PL . Molecular nature of genetic changes resulting in loss of heterozygosity of chromosome 11 in Wilms'tumours.. Human Genetics , v. 81, p. 41-8, 1988.

  • MILLINGTON-WARD, A M ; PEARSON, PL . Use of restriction fragment length polymorphic probes in the analysis of Down's syndrome trisomy.. Human Genetics , v. 80, p. 362-70, 1988.

  • VEENEMA, H ; BEVERSTOCK, G C ; KONING, T de ; PEARSON, PL ; VAN DE KAMP, J J . The fragile X-chromosome: an evaluation of the results in a routine cytogenetic laboratory in the period 1981-1986.. Clinical Genetics , v. 33, p. 410-7, 1988.

  • WIRTH, B ; DENTON, M J ; CHEN, J D ; NEUGEBAUER, M ; HALLIDAY, F B ; SCHOONEVELD, M Van ; DONALD, J ; BLEEKER-WAGEMAKERS, E M ; PEARSON, PL ; GAL, A . Two different genes for X-linked retinitis pigmentosa.. Genomics (San Diego) , v. 2, p. 263-6, 1988.

  • BAKKER, E ; SKRAASTAD, M I ; FISSER-GROEN, Y M ; VAN OMMEN, G J ; PEARSON, PL . Two additional RFLPs at the D4S10 locus, useful for Huntington's disease (HD)-family studies.. Nucleic Acids Research , v. 15, p. 9100, 1987.

  • BREUNING, M H ; MADAN, K ; VERJAAL, M ; WIJNEN, J T ; MEERA, K P ; PEARSON, PL . Human alpha-globin maps to pter-p13.3 in chromosome 16 distal to PGP.. Human Genetics , v. 76, p. 287-9, 1987.

  • BROCKER-VRIENDS, A H ; BRIET, E ; QUADT, R ; DRESSEN, J C ; BAKKER, E ; CLAASSEN-TEGELAAR, R ; KANHAI, H H ; VAN DE KAMP, J J ; PEARSON, PL . Genotype assignment of haemophilia A by use of intragenic and extragenic restriction fragment length polymorphisms.. Thrombosis and Haemostasis , v. 57, p. 131-6, 1987.

  • BAKKER, E ; VAN BROECKHOVEN, C ; BONTEN, E J ; VAN DE VOOREN, M J ; VEENEMA, H ; VAN HUL, W ; VAN OMMEN, G J ; VANDENBERGHE, A ; PEARSON, PL . Germline mosaicism and Duchenne muscular dystrophy mutations.. Nature (London) , v. 329, p. 554-6, 1987.

  • CARPENTER, N J ; VEENEMA, H ; BAKKER, E ; HOFKER, M H ; PEARSON, PL . A new DNA probe proximal to and closely linked to fragile X.. American Journal of Medical Genetics , v. 27, p. 731-2, 1987.

  • HOFKER, M H ; BERGEN, A A ; SKRAASTAD, M I ; CARPENTER, N J ; VEENEMA, H ; CONNOR, J M ; BAKKER, E ; VAN OMMEN, G J ; PEARSON, PL . Efficient isolation of X chromosome-specific single-copy probes from a cosmid library of a human X/hamster hybrid-cell line: mapping of new probes close to the locus for X-linked mental retardation. American Journal of Human Genetics , v. 40, p. 312-28, 1987.

  • MANNENS, M ; SLATER, R M ; HEYTING, C ; GEURTS VAN KESSEL, A ; GOEDDE-SALZ, E ; FRANTS, R R ; VAN OMMEN, G J ; PEARSON, PL . Regional localization of DNA probes on the short arm of chromosome 11 using aniridia-Wilms'tumor-associated deletions.. Human Genetics , v. 75, p. 180-7, 1987.

  • PEARSON, PL . Recombinant DNA, chromosomes and prenatal diagnosis.. Current Problems In Dermatology , v. 16, p. 30-44, 1987.

  • PEARSON, PL ; KIDD, K K ; WILLARD, H F . Report of the committee on human gene mapping by recombinant DNA techniques.. Cytogenetics and Cell Genetics , v. 46, p. 390-566, 1987.

  • VEENEMA, H ; GERAEDTS, J P ; BEVERSTOCK, G C ; PEARSON, PL . The fragile X syndrome in a large family. I. Cytogenetic and clinical investigations.. Journal of Medical Genetics , v. 24, p. 23-31, 1987.

  • VEENEMA, H ; CARPENTER, N J ; BAKKER, E ; HOFKER, M H ; WARD, A M ; PEARSON, PL . The fragile X syndrome in a large family. III. Investigations on linkage of flanking DNA markers with the fragile site Xq27.. Journal of Medical Genetics , v. 24, p. 413-21, 1987.

  • DEN DUNNEN, J T ; BAKKER, E ; BRETELER, e G ; PEARSON, PL ; VAN OMMEN, G J . Direct detection of more than 50% of the Duchenne muscular dystrophy mutations by field inversion gels.. Nature (London) , v. 329, p. 640-42, 1986.

  • BAKKER, E ; PEARSON, PL . Mutation of the Duchenne muscular dystrophy gene associated with meiotic recombination.. Clinical Genetics , v. 30, p. 347-9, 1986.

  • BAKKER, E ; BONTEN, E J ; LANGE, L F de ; VEENEMA, H ; MAJOOR-KRAKAUER, D ; HOFKER, M H ; VAN OMMEN, G J ; PEARSON, PL . DNA probe analysis for carrier detection and prenatal diagnosis of Duchenne muscular dystrophy: a standard diagnostic procedure.. Journal of Medical Genetics , v. 23, p. 573-80, 1986.

  • BREUNING, M H ; PEEDERS, S T ; GOOR, N ; HOGEWIND, B L ; VAN ES, L A ; PEARSON, PL . [Localization of the gene for the adult form of polycystic kidneys on the short arm of chromosome 16].. Ned Tijdschr Geneeskd , v. 130, p. 689-92, 1986.

  • CREMER, T ; LANDEGENT, J ; BRUCKNER, A ; SCHOLL, H P ; SCHARDIN, M ; HAGER, H D ; DEVILEE, P ; PEARSON, PL ; VAN DER PLOEG, M . Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84.. Human Genetics , v. 74, p. 346-352, 1986.

  • DEVILEE, P ; SLAGBOOM, P ; CORNELISSE, C J ; PEARSON, PL . Sequence heterogeneity within the human alphoid repetitive DNA family.. Nucleic Acids Research , v. 14, p. 2059-73, 1986.

  • DEVILEE, P ; CREMER, T ; SLAGBOOM, P A ; BAKKER, E ; SCHOLL, H P ; HAGER, H D ; STEVENSON, A F ; CORNELISSE, C J ; PEARSON, PL . Two subsets of human alphoid repetitive DNA show distinct preferential localization in the pericentric regions of chromosomes 13, 18, and 21.. Cytogenetics and Cell Genetics , v. 41, p. 193-201, 1986.

  • DUNGER, D B ; DAVIES, K E ; PEMBREY, M ; LAKE, B ; PEARSON, PL ; WILLIAMS, D ; WHITFIELD, A ; DILLON, M J . Deletion on the X chromosome detected by direct DNA analysis in one of two unrelated boys with glycerol kinase deficiency, adrenal hypoplasia, and Duchenne muscular dystrophy.. Lancet , v. 1, p. 585-7, 1986.

  • HOFKER, M H ; SKRAASTAD, M I ; BERGEN, A A ; WAPENAAR, M C ; BAKKER, E ; MILLINGTON-WARD, A ; VAN OMMEN, G J ; PEARSON, PL . The X chromosome shows less genetic variation at restriction sites than the autosomes.. American Journal of Human Genetics , v. 39, p. 438-51, 1986.

  • HOFKER, M H ; VAN OMMEN, G J ; BAKKER, E ; BURMEISTER, M ; PEARSON, PL . Development of additional RFLP probes near the locus for Duchenne muscular dystrophy by cosmid cloning of the DXS84 (754) locus.. Human Genetics , v. 74, p. 270-4, 1986.

  • HOFKER, M H ; BERGEN, A A ; SKRAASTAD, M I ; BAKKER, E ; FRANCKE, U ; WIERINGA, B ; BARTLEY, J ; VAN OMMEN, G J ; PEARSON, PL . Isolation of a random cosmid clone, cX5, which defines a new polymorphic locus DXS148 near the locus for Duchenne muscular dystrophy.. Human Genetics , v. 74, p. 275-9, 1986.

  • JANSSEN, J W ; COLLARD, J G ; TULP, A ; COX, D ; MILLINGTON-WARD, A ; PEARSON, PL . Construction and analysis of an EMBL-3 phage library containing partially digested human chromosome 21-specific DNA inserts (15-20 kb).. Cytometry , v. 7, p. 411-7, 1986.

  • LANDEGENT, J e ; JANSEN IN DE WAL, N ; FISSER-GROEN, Y M ; BAKKER, E ; VAN DER PLOEG, M ; PEARSON, PL . Fine mapping of the Huntington disease linked D4S10 locus by non-radioactive in situ hybridization.. Human Genetics , v. 73, p. 354-7, 1986.

  • LOTHE, R A ; GEDDE-DAHL, T ; OLAISEN, B ; BAKKER, E ; PEARSON, PL . Very close linkage between D2S1 and ACP1 on chromosome 2p.. Annals of Human Genetics , v. Pt 4, p. 361-7, 1986.

  • REEDERS, S T ; BREUNING, M H ; CORNEY, G ; JEREMIAH, S J ; MEERA KHAN, P ; DAVIES, K E ; HOPKINSON, D A ; PEARSON, PL ; WEATHERALL, D J . Two genetic markers closely linked to adult polycystic kidney disease on chromosome 16.. BMJ. British Medical Journal , v. 292, p. 851-3, 1986.

  • SCHEFFER, H ; LELIE, D Van Der ; AANSTOOT, G H ; GOOR, N ; NIENHAUS, A J ; VAN DER HOUT, A H ; PEARSON, PL ; BUYS, C H . A straightforward approach to isolate DNA sequences with potential linkage to the retinoblastoma locus.. Human Genetics , v. 74, p. 249-55, 1986.

  • SCHEFFER, H ; PENNINGA, D ; GOOR, N ; BUYS, C H ; PEARSON, PL . A four-allele RFLP identified by an anonymous single copy genomic clone at 13q21-13qter [HGM8 assignment no. D13S12].. Nucleic Acids Research , v. 14, p. 4374, 1986.

  • SCHEFFER, H ; PENNINGA, D ; GOOR, N ; PEARSON, PL ; BUYS, C H . An anonymous single copy genomic clone at 13q12-13q13 identifies three RFLPs [HGM8 assignment no. D13S11].. Nucleic Acids Research , v. 14, p. 3148, 1986.

  • VAN OMMEN, G J ; VERKERK, J M ; HOFKER, M H ; MONACO, A P ; KUNKEL, L M ; RAY, P ; WORTON, R ; WIERINGA, B ; BAKKER, E ; PEARSON, PL . A physical map of 4 million bp around the Duchenne muscular dystrophy gene on the human X-chromosome.. Cell, v. 47, p. 499-504, 1986.

  • VROLIJK, J ; KORTHOF, G ; VLETTER, G ; VAN DE GEEST, C R ; GERRESE, G M ; PEARSON, PL . The automation of culturing and harvesting of human chromosome specimens.. Histochemistry , v. 84, p. 586-93, 1986.

  • PEARSON, PL ; VAN OMMEN, G J ; BAKKER, E . Carrier detection and gene analysis of Duchenne muscular dystrophy.. Cold Spring Harbor Symposia on Quantitative Biology , v. Pt 1, p. 353-8, 1986.

  • BAAS, F ; BIKKER, H ; GEURTS VAN KESSEL, A ; MELSERT, R ; PEARSON, PL ; DE VIJLDER, J J ; VAN OMMEN, G J . The human thyroglobulin gene: a polymorphic marker localized distal to C-MYC on chromosome 8 band q24.. Human Genetics , v. 69, p. 138-43, 1985.

  • PEARSON, PL ; BAKKER, E ; HOFKER, M H ; GOOR, N ; MANDEL, J L ; WROGEMANN, K ; DAVIES, K E ; KUNKEL, L M ; WILLARD, H F ; FENTON, W A ; SANDKUYL, L . Prenatal diagnosis and carrier detection of Duchenne muscular dystrophy with closely linked RFLPs.. Lancet , v. 1, p. 655-8, 1985.

  • BOLHUIS, P A ; BAAS, F ; VAN OMMEN, G J ; PEARSON, PL ; VISSER, M de . DNA analysis and genetic counseling.. Ned Tijdschr Genneskd , v. 129, p. 1134-6, 1985.

  • BRIET, E ; BROCKER-VRIENDS, A ; QUADT, R ; BERTINA, R M ; VAN DER LINDEN, I K ; VAN DE KAMP, J J ; PEARSON, PL ; VELTKAMP, J J . Search for the carrier state of hemophilia B using restriction fragment length polymorphism.. Ned Tijdschr Geneeskd , v. 129, p. 1141-5, 1985.

  • BROCKER-VRIENDS, A H ; BRIET, E ; QUADT, R ; BERTINA, R M ; VAN DER LINDEN, I K ; VAN DE KAMP, J J ; PEARSON, PL ; VELTKAMP, J J . Carrier detection of haemophilia B by using an intragenic restriction-fragment length polymorphism.. Thrombosis and Haemostasis , v. 54, p. 506-9, 1985.

  • BROWN, C S ; THOMAS, N S ; SARFARAZZI, M ; DAVIES, K E ; KUNKEL, L ; PEARSON, PL ; KINGSTON, M H ; SHAW, D J ; HARPER, P S . Genetic linkage relationships of seven DNA probes with Duchenne and Becker muscular dystrophy.. Human Genetics , v. 71, p. 62-74, 1985.

  • DEROM, C ; BAKKER, E ; VLIETINCK, R ; DEROM, R ; VAN DER BERGHE, H ; THIERY, M ; PEARSON, PL . Zygosity determination in newborn twins using DNA variants.. Journal of Medical Genetics , v. 22, p. 279-82, 1985.

  • FRANCKE, U ; OCHS, H D ; GIACALONE, J ; DE MARTINVILLE, B ; LINDGREN, V ; DISTECHE, C ; PAGON, R A ; HOFKER, M H ; VAN OMMEN, G J ; PEARSON, PL . Minor Xp21 chromosome deletion in a male associated with expression of Duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa, and McLeod syndrome.. American Journal of Human Genetics , v. 37, p. 250-67, 1985.

  • GAL, A ; STOLZENBERGER, C ; WINKER, T ; WIEACKER, P ; ROOPERS, H H ; FRIEDRICH, U ; BLEEKER-WAGEMAKERS, L ; PEARSON, PL ; WARBURG, M . Norrie's disease: close linkage with genetic markers from the proximal short arm of the X chromosome.. Clinical Genetics , v. 27, p. 282-3, 1985.

  • HOFKER, M H ; WAPENNAR, M C ; GOOR, N ; BAKKER, E ; VAN OMMEN, G J ; PEARSON, PL . Isolation of probes detecting restriction fragment length polymorphisms from X chromosome-specific libraries: potential use for diagnosis of Duchenne muscular dystrophy.. Human Genetics , v. 70, p. 148-56, 1985.

  • HOFKER, M H ; BREUNING, M H ; BAKKER, E ; VAN OMMEN, G J ; PEARSON, PL . An anonymous single copy chromosome 22 clone, D22S10 (22c1-18) identifies an RFLP with PstI.. Nucleic Acids Research , v. 13, p. 7167, 1985.

  • INGLE, C ; WILLIAMSON, R ; CHAPELLE, A de La ; HERVA, R R ; HAAPALA, K ; BATES, G ; WILLARD, H F ; PEARSON, PL ; DAVIS, K E . Mapping DNA sequences in a human X-chromosome deletion which extends across the region of the Duchenne muscular dystrophy mutation.. American Journal of Human Genetics , v. 37, p. 451-62, 1985.

  • OLD, J M ; BRIAND, P L ; PURVIS-SMITH, S ; HOWARD, N J ; WILCKEN, B ; HAMMOND, J ; PEARSON, PL ; CATHELINEAU, L ; WILLIAMSON, R ; DAVIES, K E . Prenatal exclusion of ornithine transcarbamylase deficiency by direct gene analysis.. Lancet , v. 1, p. 73-5, 1985.

  • PEARSON, PL . Restriction fragment length polymorphisms (RFLP's) and their use in mapping the human genome.. Prog Clin Biol Res , v. 177, p. 23-36, 1985.

  • REEDERS, S T ; BREUNING, M H ; DAVIES, K E ; NICHOLLS, R D ; JARMAN, A P ; HIGGS, D R ; PEARSON, PL ; WEATHERALL, D J . A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16.. Nature (London) , v. 317, p. 542-4, 1985.

  • VEENEMA, H ; LESCHOT, N J ; VAN OMMEN, G J ; PEARSON, PL . [Importance of recombinant DNA studies for the identification of carriers of Duchenne's muscular dystrophy]. Ned Tijdschr Geneeskd , v. 129, p. 1137-41, 1985.

  • WILCOX, D e ; AFFARA, N A ; YATES, J R ; FERGUSON-SMITH, M A ; PEARSON, PL . Multipoint linkage analysis of the short arm of the human X chromosome in families with X-linked muscular dystrophy.. Human Genetics , v. 70, p. 365-75, 1985.

  • WILLARD, H F ; SKOLNICK, M H ; PEARSON, PL ; MANDEL, J L . Committee on Human Gene Mapping by Recombinant DNA Techniques.. Cytogenetics and Cell Genetics , v. 40, p. 360-89, 1985.

  • MERKLER, P ; DELEHANTY, D J ; LOHMAN, P H ; BROUWER, J ; VD PUTTE, P ; PEARSON, PL ; RAMEL, C . International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Publication No. 11. The use of recombinant DNA technology to study gene alteration.. Mutation Research , v. 153, p. 13-55, 1985.

  • BHATTACHARYA, S S ; WRIGHT, A F ; CLAYTON, J F ; PRICE, W H ; PHILLIPS, C I ; MCKEOWN, C M ; JAY, M ; BIRD, A C ; PEARSON, PL ; SOUTHERN, E M . Close genetic linkage between X-linked retinitis pigmentosa and a restriction fragment length polymorphism identified by recombinant DNA probe L1.28.. Nature (London) , v. 309, p. 253-5, 1984.

  • CAVENEE, W ; LEACH, R ; MOHANDAS, T ; PEARSON, PL ; WHITE, R . Isolation and regional localization of DNA segments revealing polymorphic loci from human chromosome 13.. American Journal of Human Genetics , v. 36, p. 10-24, 1984.

  • HOPPENER, J W ; STEENBERGH, P H ; ZANDBERG, J ; BAKKER, E ; PEARSON, PL ; GEURTS VAN KESSEL, A H ; JANSZ, H S ; LIPS, C J . Localization of the polymorphic human calcitonin gene on chromosome 11.. Human Genetics , v. 66, p. 309-12, 1984.

  • MEERA KHAN, P ; WIJNEN, L M ; HAGEMEIJER, A ; PEARSON, PL . Human formaldehyde dehydrogenase (FDH) and its assignment to chromosome 4.. Cytogenetics and Cell Genetics , v. 38, p. 112-5, 1984.

  • WIEACKER, P ; DAVIES, K E ; COOKE, H J ; PEARSON, PL ; WILLIAMSON, P ; BHATTACHARYA, S ; ZIMMER, J ; ROOPERS, H H . Toward a complete linkage map of the human X chromosome: regional assignment of 16 cloned single-copy DNA sequences employing a panel of somatic cell hybrids.. American Journal of Human Genetics , v. 36, p. 265-76, 1984.

  • HERBSCHLEB-VOOGT, E ; SCHOLTEN, J W ; VOSSEN, J M ; PEARSON, PL ; MEERA KHAN, P . Basic molecular defect in ADA-SCID.. Advances in Experimental Medicine and Biology , v. 165A, p. 381-4, 1984.

  • DAVIES, K E ; PEARSON, PL ; HARPER, P S ; MURRAY, J M ; O´BRIEN, T ; SARFARAZI, M ; WILLIAMSON, R . Linkage analysis of two cloned DNA sequences flanking the Duchenne muscular dystrophy locus on the short arm of the human X chromosome.. Nucleic Acids Research , v. 11, p. 2303-12, 1983.

  • DERKS, J P ; PEARSON, PL . Some immunochemical aspects of HD-brain extracts.. Clinical Immunology and Immunopathology , v. 28, p. 341-9, 1983.

  • ESTOP, A M ; GARVER, J J ; EGOZCUE, J ; MEERA KHAN, P ; PEARSON, PL . Complex chromosome homologies between the rhesus monkey (Macaca mulatta) and man.. Cytogenetics and Cell Genetics , v. 35, p. 46-50, 1983.

  • HARPER, P S ; O´BRIEN, T ; MURRAY, J M ; DAVIES, K E ; PEARSON, PL ; WILLIAMSON, R . The use of linked DNA polymorphisms for genotype prediction in families with Duchenne muscular dystrophy.. Journal of Medical Genetics , v. 20, p. 252-4, 1983.

  • KINGSTON, M H ; THOMAS, N S ; PEARSON, PL ; SARFARAZI, M ; HARPER, P S . Genetic linkage between Becker muscular dystrophy and a polymorphic DNA sequence on the short arm of the X chromosome.. Journal of Medical Genetics , v. 20, p. 255-8, 1983.

  • KINGSTON, H M ; HARPER, P S ; PEARSON, PL ; DAVIES, K E ; WILLIAMSON, R ; PAGE, D . Localisation of gene for Becker muscular dystrophy.. Lancet , v. 2, p. 1200, 1983.

  • WIEACKER, P ; DAVIES, K ; PEARSON, PL ; ROOPERS, H H . Carrier detection in Duchenne muscular dystrophy by use of cloned DNA sequences.. Lancet , v. 1, p. 1325-6, 1983.

  • WIEACKER, P ; HORN, N ; PEARSON, PL ; WIENKER, T F ; MCKAY, E ; ROOPERS, H H . Menkes kinky hair disease: a search for closely linked restriction fragment length polymorphism.. Human Genetics , v. 64, p. 139-42, 1983.

  • BEVERSTOCK, G C ; PEARSON, PL . Electron spin resonance studies of erythrocyte ghost cells in Huntington's chorea.. Acta Neurologica Scandinavica , v. 65, p. 413-23, 1982.

  • CAVALLI-SFORZA, L ; DAVIES, K ; SMITH, K ; PEARSON, PL ; GERALD, P ; NAYLOR, S ; KAZAZIAN, H ; WHITE, R ; ELLIOT, R ; CRIPPA, L ; YOUNG, B ; SKOLNICK, M ; NEI, M . Workshop on DNA polymorphisms.. Prog Clin Biol Res , v. 103 A, p. 79-81, 1982.

  • PEARSON, PL ; DERKS, J P . The unsuitability of the leukocyte adherence inhibition assay for diagnosis of Huntington's chorea.. Clinical Immunology and Immunopathology , v. 25, p. 354-61, 1982.

  • PEARSON, PL ; RODERICK, T H ; DAVISSON, M T ; LALLEY, P A ; O´BRIEN, S J . Report of the committee on comparative mapping. Oslo Conference (1981): Sixth International Workshop on Human Gene Mapping.. Cytogenetics and Cell Genetics , v. 32, p. 208-20, 1982.

  • BEVERSTOCK, G C ; PEARSON, PL . Membrane fluidity measurements in peripheral cells from Huntington's disease patients.. Journal of Neurology, Neurosurgery and Psychiatry , v. 44, p. 684-9, 1981.

  • GEURTS VAN KESSEL, A H ; TEN BRINKE, H ; BOERE, W A ; BOER, W C Den ; GROOT, P G de ; HAGEMEIJER, A ; MEERA KHAN, P ; PEARSON, PL . Characterization of the Philadelphia chromosome by gene mapping.. Cytogenetics and Cell Genetics , v. 30, p. 83-91, 1981.

  • HERBSCHLEB-VOOGT, E ; PEARSON, PL ; VOSSEN, J M ; MEERA, K P . Basic defect in the expression of adenosine deaminase in ADA- SCID disease investigated through the cells of an obligate heterozygote.. Human Genetics , v. 56, p. 379-86, 1981.

  • HERBSCHLEB-VOOGT, E ; GRZESCHIK, K H ; PEARSON, PL ; MEERA, K P . Assignment of adenosine deaminase complexing protein (ADCP) gene(s) to human chromosome 2 in rodent-human somatic cell hybrids.. Human Genetics , v. 59, p. 317-23, 1981.

  • MEEL, F C Van ; BEVERSTOCK, G C ; PEARSON, PL ; DAEMS, W T . Electron microscopic studies on the incorporation of human spermatozoa into mouse fibroblasts following Sendai virus fusion.. Journal of Ultrastructure Research , v. 75, p. 142-50, 1981.

  • [No authors listed] ; PEARSON, PL . Signatory to: An international system for human cytogenetic nomenclature-high-resolution banding (1981). ISCN (1981). Report of the Standing Committee on Human Cytogenetic Nomenclature.. Cytogenetics and Cell Genetics , v. 31, p. 5-23, 1981.

  • GARVER, J ; PEARSON, PL ; ABRAHAMS, P J ; VAN DEN EB, A J . Control of sv40 replication by a simple chromosome in monkey-hamster cell hybrids. Somatic Cell Genetics , v. 6, p. 443-53, 1980.

  • GARVER, J J ; ESTOP, A M ; MEERA, K P ; BALNER, H ; PEARSON, PL . Evidence of similar organization of the chromosomes carrying the major histocompatibility complex in man and other primates.. Cytogenetics and Cell Genetics , v. 27, p. 238-45, 1980.

  • PEARSON, PL ; RODERICK, T H ; DAVISSON, M T ; GRAVER, J J ; WARBURTON, D ; LALLEY, P A ; O´BRIEN, S J . Report of the committee on comparative mapping.. Birth defects . Original article series , v. 15, p. 82-95, 1980.

  • VROLIJK, J ; PEARSON, PL ; PLOEM, J S . LEYTAS: a system for the processing of microscopic images.. Analytical and Quantitative Cytology and Histology , v. 2, p. 41-8, 1980.

  • VROLIJK, J ; TEN BRINKE, H ; PLOEM, J S ; PEARSON, PL . Video techniques applied to chromosome analysis.. Microscopica Acta Supplement , v. 4, p. 108-15, 1980.

  • AL, I ; CORNELISSE, C J ; PEARSON, PL ; PLOEM, J S . Automated chromatin analysis using the Leyden Television Analysis System (LEYTAS).. Acta Histochemica Suppl , v. 20, p. 211-5, 1979.

  • PEARSON, PL ; BAKKER, E ; MEERA, K P ; SCHREUDER, G M ; MADAN, K . Orientation of major histocompatibility (MHC) genes relative to the centromere of human chromosome 6.. Clinical Genetics , v. 15, p. 198-202, 1979.

  • PEARSON, PL ; RODERICK, T H ; DAVISSON, M T . Report of the committee on comparative mapping.. Cytogenetics and Cell Genetics , v. 25, p. 82-95, 1979.

  • TATES, A D ; PEARSON, PL ; VAN DER PLOEG, M ; DE VOGEL, N . The induction of sex-chromosomal nondisjunction and diploid spermatids following x-irradiation of pre-spermatid stages in the northern vole Microtus oeconomus.. Mutation Research , v. 61, p. 87-101, 1979.

  • MEEL, F C Van ; PEARSON, PL . Do human spermatozoa reactivate in the cytoplasm of somatic cells?. Journal of Cell Science , v. 35, p. 105-22, 1979.

  • MEEL, F C Van ; PEARSON, PL . Replacement of protamine by F1 histone during reactivation of fused human sperm nuclei.. Histochemestry , v. 63, p. 329-39, 1979.

  • [No authors listed] ; PEARSON, PL . Signatory to: An international system for human cytogenetic nomenclature (1978) ISCN (1978). Report of the Standing Commitee on Human Cytogenetic Nomenclature.. Cytogenetics and Cell Genetics , v. 21, p. 309-409, 1978.

  • ESTOP, A ; GARVER, J J ; PEARSON, PL ; DIJKSMAN, T M ; WIJNEN, L M ; MEERA, K P . Gene assignments to the presumptive homologs of human chromosomes 3, 4, 5, 7, 8, 10, 18, 19, 20, and 21 in the Pongidae and Cercopithecoidea.. Cytogenetics and Cell Genetics , v. 22, p. 558-63, 1978.

  • GARVER, J J ; PEARSON, PL ; ESTOP, A ; DIJKSMAN, T M ; WIJNEN, L M ; WESTERVELD, A ; MEERA KHAN, P . Gene assignments to the presumptive homologs of human chromosomes 1, 6, 11, 12, and X in the Pongidae and Cercopithecoidea.. Cytogenetics and Cell Genetics , v. 22, p. 564-9, 1978.

  • HERBSCHLEB-VOOGT, E ; MONTEBA VAN HEUVEL, M ; WIJNEN, L M ; WESTERVELD, A ; PEARSON, PL ; MEERA, K P . Chromosomal assignment and regional localization of CS, ENO2, GAPDH, LDHB, PEPB, and TPI in man-rodent cell hybrids.. Cytogenetics and Cell Genetics , v. 22, p. 482-6, 1978.

  • MEERA, K P ; WIJNEN, L M ; PEARSON, PL . Assignment of the mitochondrial aconitase gene (ACONM) to human chromosome 22.. Cytogenetics and Cell Genetics , v. 22, p. 212-4, 1978.

  • MEERA, K P ; WIJNEN, L M ; PEARSON, PL . Assignment of a human galactose-1-phosphate uridylyltransferase gene (GALT1) to chromosome 9 in human-Chinese hamster somatic cell hybrids.. Cytogenetics and Cell Genetics , v. 22, p. 207-11, 1978.

  • PEARSON, PL ; GARVER, J J ; ESTOP, A ; DIJKSMAN, T M ; WIJNEN, L M ; MEERA, K P . Gene assignments to the presumptive homologs of human chromosomes 2, 9, 13, 14, and 15 in the Pongidae and Cercopithecoidea.. Cytogenetics and Cell Genetics , v. 22, p. 588-93, 1978.

  • PEARSON, PL ; WITTERLAND, W F ; MEERA, K P ; DE WITT, J ; BOBROW, M . Reinvestigation of two X/autosome translocations:segregation in cell hybrids.. Cytogenetics and Cell Genetics , v. 22, p. 534-7, 1978.

  • WESTERVELD, A ; GARVER, J J ; NIJMAN, M A ; PEARSON, PL . Regional localization of the genes coding for human red cell adenylate kinase, aconitase, and galactose-1-phosphate uridylyltransferase on chromosome 9.. Cytogenetics and Cell Genetics , v. 22, p. 465-7, 1978.

  • WIJNEN, L M ; Monteba-van HEUVEL, M ; PEARSON, PL ; MEERA KHAN, P . Assignment of a gene for glutathione peroxidase (GPX1) to human chromosome 3.. Cytogenetics and Cell Genetics , v. 22, p. 232-5, 1978.

  • WIJNEN, L M ; GRZESCHIK, K H ; PEARSON, PL ; MEERA, K P . The human PGM-2 and its chromosomal localization in man-mouse hybrids.. Human Genetics , v. 37, p. 271-8, 1977.

  • WIJNEN, L M ; GRZESCHIK, K H ; PEARSON, PL ; MEERA, K P . Direct assignment of citrate synthase (CS) gene to human chromosome 12 in man-mouse somatic cell hybrids.. Human Genetics , v. 39, p. 339-44, 1977.

  • MEERA, K P ; PEARSON, PL ; WIJNEN, L L ; DOPPERT, B A ; WESTERVELD, A ; BOOTSMA, D . Assignment of inosine triphosphatase gene to gorilla chromosome 13 and to human chromosome 20 in primate-rodent somatic cell hybrids.. Birth Defects Orig Artic Ser, v. 12, p. 420-1, 1976.

  • DE WITT, J ; BOOTSMA, D ; PEARSON, PL ; WESTERVELD, A . Regional mapping of the human No. 1 and X chromosome in interspecific cell hybrids using an X/1 translocation.. Cytogenetics and Cell Genetics , v. 15, p. 129-37, 1975.

  • FELLOUS, M ; PEARSON, PL ; VAN DER LINDEN, A G ; MEERA, K P ; HAGEMEIJER, A . Mapping the Xga red blood cell antigen in human-Chinese hamster cell hybrids. The Xg locus is possibly located on the short arm of the X chromosome.. Birth defects . Original article series , v. 11, p. 123-5, 1975.

  • GERAEDTS, J P ; PEARSON, PL ; VAN DER, P M ; VOSSEPOEL, A M . Polymorphisms for human chromosomes 1 and Y. Feulgen and UV DNA measurements.. Experimental Cell Research , v. 95, p. 9-14, 1975.

  • GERAEDTS, J P ; PEARSON, PL . Spatial distribution of chromosomes 1 and Y in human spermatozoa.. Journal of Reproduction and Fertility , v. 45, p. 515-7, 1975.

  • PEARSON, PL ; GERAEDTS, J P ; VAN DE PLOEG, M ; PAWLOWITZKI, I H . Chromosome studies on human male gametes.. Biological Journal of the Linnean Society , v. 7, p. 279-89, 1975.

  • TATES, A D ; PEARSON, PL ; GERAEDTS, J P . Identification of X and Y spermatozoa in the northern vole, Microtus oeconomus.. Journal of Reproduction and Fertility , v. 42, p. 195-8, 1975.

  • VAN DER LINDEN, A G ; PEARSON, PL ; VAN DE KAMP, J J . Cytological assessment of meiotic exchange in a human male with a pericentric inversion of chromosome No. 4.. Cytogenetics and Cell Genetics , v. 14, p. 126-39, 1975.

  • DOEGLAS, H M ; BERNINI, L F ; FRASER, G R ; VAN LOGHEM, E ; MEERA KHAN, P ; NYENHUIS, L e ; PEARSON, PL . A kindred with familial cold urticaria: linkage analysis.. Journal of Medical Genetics , v. 11, p. 31-4, 1974.

  • EVANS, H J ; PEARSON, PL . Proceedings: Report of the Committee on Chromosome Markers.. Cytogenetics and Cell Genetics , v. 13, p. 58-62, 1974.

  • GERAEDTS, J P ; PEARSON, PL . Fluorescent chromosome polymorphisms: frequencies and segregations in a Dutch population.. Clinical Genetics , v. 6, p. 247-57, 1974.

  • MEERA, K P ; LOS, W R ; PEARSON, PL ; WESTERVELD, A ; BOOTSMA, D . Genetical studied on the multiple forms of human guanylate kinase in man-chinese hamster somatic cell hybrids.. Human Heredity. International Journal of Human and Medical Genetics , v. 24, p. 415-23, 1974.

  • PEARSON, PL ; VAN DER LINDEN, A G ; HAGEMEIJER, A . Proceedings: Localization of gene markers to regions of the human X chromosome by segregation of X-autosome translocations in somatic cell hybrids.. Cancer Genetics and Cytogenetics , v. 13, p. 136-42, 1974.

  • ALDERDICE, P W ; MILLER, O J ; PEARSON, PL ; KLEIN, G ; HARRIS, H . Human chromosomes in 18 man-mouse somatic hybrid cell lines analysed by quinacrine fluorescence.. Journal of Cell Science , v. 12, p. 809-30, 1973.

  • ALLDERDICE, P W ; MILLER, C J ; MILLER, D A ; WARBURTON, D ; PEARSON, PL ; KLEIN, G ; HARRIS, H . Chromosome analysis of two related heteroploid mouse cell lines by quinacrine fluorescence. Journal of Cell Science , v. 12, p. 263-74, 1973.

  • GERAEDTS, J ; PEARSON, PL . Specific staining of the human No. 1 chromosome in spermatozoa. Humangenetik, v. 20, p. 171-173, 1973.

  • JONGSMA, A ; VAN SOMEREN, H ; WESTERVELD, A ; HAGEMEIJER, A ; PEARSON, PL . Localization of genes on human chromosomes by studies of human-Chinese hamster somatic cell hybrids. Assignment of PGM3 to chromosome C6 and regional mapping of the PGD, PGM1 and pep-C genes on chromosome A1.. Humangenetik, v. 20, p. 195-202, 1973.

  • PEARSON, PL . The behavior of chromosomes.. Advances In The Bioscience , v. 10, p. 15-26, 1973.

  • [No authors listed] ; PEARSON, PL . The Paris nomenclature.. Journal of Medical Genetics , v. 10, p. 127-8, 1973.

  • BOBROW, M ; MADAN, K ; PEARSON, PL . Staining of some specific regions of human chromosomes, particularly the secondary constriction of No. 9.. Nature New Biology , v. 238, p. 122-4, 1972.

  • PAWLOWITZKI, I H ; PEARSON, PL . Chromosomal aneuploidy in human spermatozoa.. Humangenetik, v. 16, p. 119-22, 1972.

  • PEARSON, PL . The use of new staining techniques for human chromosome identification.. Journal of Medical Genetics , v. 9, p. 264-75, 1972.

  • [No authors listed] ; PEARSON, PL . Paris Conference (1971): standardization in human cytogenetics.. Birth defects . Original article series , v. 8, p. 1-46, 1972.

  • BOBROW, M ; PEARSON, PL . The use of quinacrine fluorescence in the identification of B and E group chromosomes involved in structural abnormalities.. Journal of Medical Genetics , v. 8, p. 240-3, 1971.

  • PEARSON, PL ; BOBROW, M ; PIKE, M C ; EL ALFI, O S . Length variation in the quinacrine-binding segment of human Y chromosomes of different sizes.. Cytogenetics , v. 10, p. 190-8, 1971.

  • BOBROW, M ; PEARSON, PL ; COLLACOTT, H E . Para-nucleolar position of the human Y chromosome in interphase nuclei.. Nature (London) , v. 232, p. 556-7, 1971.

  • HULTEN, M ; PEARSON, PL . Fluorescent evidence for spermatocytes with two Y chromosomes in an XYY male.. Annals of Human Genetics , v. 34, p. 273-6, 1971.

  • PEARSON, PL ; BOBROW, M ; VOSA, C G ; BARLOW, P W . Quinacrine fluorescence in mammalian chromosomes.. Nature (London) , v. 231, p. 326-9, 1971.

  • PEARSON, PL ; ELLIS, J D ; EVANS, H J . A gross reduction in chiasma formation during meiotic prophase and a defective DNA repair mechanism associated with a case of human male infertility.. Cytogenetics , v. 9, p. 460-7, 1970.

  • PEARSON, PL ; BOBROW, M . Fluorescent staining of the Y chromosome in meiotic stages of the human male.1970. Journal of Reproduction and Fertility , v. 22, p. 177-9, 1970.

  • PEARSON, PL ; BOBROW, M . Definitive evidence for the short arm of the Y chromosome associating with the X chromosome during miosis in the human male.. Nature (London) , v. 226, p. 959-61, 1970.

  • PEARSON, PL ; BOBROW, M ; VOSA, C G . Technique for identifying Y chromosomes in human interphase nuclei.. Nature (London) , v. 226, p. 78-80, 1970.

  • PEARSON, PL ; CLARKE, G ; DAVISON, B C ; LENNOX, I G ; PRICHARD, P M . Segregation of a D-G translocation in three families.. J Ment Defic Res, v. 13, p. 209-11, 1969.

  • PEARSON, PL ; VELDE, E R ; BROEKMANS, F . Female Reproductive Aging. Parthenon Publishing Group, 2004.

  • CUTICCHIA, A J ; PEARSON, PL . Human Gene Mapping 1993, A Compendium. Johns Hopkins University Press,, 1994.

  • PEARSON, PL ; LEWIS, Jke . Chromosomes Today.. New York: Wiley&Sons Ltd,, 1974.

  • PEARSON, PL . Jerome Lejeune. In: Sydney Brenner; Jeffrey Miller. (Org.). Encyclopedia of Genetics. : Academic Press, 2004, v. , p. 1085-7.

  • PEARSON, PL . Trisomy. In: Sydney Brenner; Jeffrey Miller. (Org.). Encyclopedia of Genetics. : Academic Press, 2004, v. , p. 2056-58.

  • PEARSON, PL . Chromosome Mapping. In: Sydney Brenner; Jeffrey Miller. (Org.). Encyclopedia of Genetics. : Academic Press, 2004, v. , p. 353-67.

  • PEARSON, PL . Triploidy. In: Sydney Brenner; Jeffrey Miller. (Org.). Encyclopedia of Genetics. : Academic Press, 2004, v. , p. 2055-6.

  • PEARSON, PL . Genetic parameters of oocyte aging.. In: Pearson PL; Velde ER. (Org.). Female Reproductive Aging. : Parthenon Publishing Group, 2000, v. , p. 137-47.

  • PEARSON, PL ; SCHINZEL, A A ; MCKUSICK, V ; FRANCOMANO, C . Report of the committee for clinical disorders and chromosome aberrations.. In: Cuticchia AJ; Pearson PL. (Org.). Human Gene Mapping 1993, A Compendium. : Baltimore: Johns Hopkins Press, 1994, v. , p. 735-72.

  • PEARSON, PL ; LUCIER, R ; C, Brunn . Databases to serve the Genome Program and the the medical genetics community. In: Lindsten J; Petterson U. (Org.). Etiology of Human Disease at the DNA Level. : Raven Press, 1991, v. , p. 23-33.

  • BOSMAN, F T ; VAN VLOTEN, W A ; PEARSON, PL . Cytogenetic and cytochemical observations in patients with the Sezary syndrome. In: Pearson PL; Lewis JK. (Org.). Chromosomes Today. : New York: Wiley&Sons Ltd, 1974, v. , p. -.

  • PEARSON, PL ; GERAEDTS, J P . Chromosomes in Human Spermatozoa. In: Pearson PL; Lewis JK. (Org.). Chromosomes Today. : New York: Wiley&Sons Ltd., 1974, v. , p. 235-9.

  • PEARSON, PL . The uniqness of the human karyotype .. In: Caspersson T; Zech L,. (Org.). Chromosome identification; technique and applications in biology and medicine. : , 1973, v. , p. 145-5.

  • PEARSON, PL . The identification of mammalian chromosomes by differential staining techniques .. In: Smith B; Pain R. (Org.). New techniques in biophysics and cell biology. : Wiley London, 1972, v. , p. 183-509.

  • Bueno, Daniela Franco ; Sunaga, Daniele Yumi ; Kobayashi, Gerson Shigeru ; Aguena, Meire ; Raposo-Amaral, Cassio Eduardo ; Masotti, Cibele ; Cruz, Lucas Alvizi ; Pearson, Peter Lees ; Passos-Bueno, Maria Rita . Human Stem Cell Cultures from Cleft Lip/Palate Patients Show Enrichment of Transcripts Involved in Extracellular Matrix Modeling By Comparison to Controls. Stem Cell Reviews , 2010.

Prêmios

1992

Appointed Foreign Member of Dutch Royal Academy of Sciences, .

1991

Samuel Wiener Distinguished Visiting Professor, University of Manitoba, .

1990

Recipient of Cedric Carter Medal, British Clinical Genetics Society, .

1990

Recipient of Medical Faculty Medal, University of Leiden, .

1989

Appointed Life Member of Dutch Human Genetics Society, .

Histórico profissional

Endereço profissional

  • Universidade de São Paulo, Instituto de Biociências, Departamento de Biologia. , Rua Do Matão, 277, Butantã, 05508900 - Sao Paulo, SP - Brasil, URL da Homepage:

Experiência profissional

1995 - 2003

Utrecht University

Vínculo: Servidor Público, Enquadramento Funcional: Professor titular, Carga horária: 40

Atividades

  • 03/1995 - 12/2003

    Direção e administração, Departamento de Genetica Medica, .,Cargo ou função, Chefe de Departamento.

1989 - 1995

Johns Hopkins University

Vínculo: Celetista, Enquadramento Funcional: Professor titular, Carga horária: 40

Atividades

  • 02/1989 - 02/1995

    Direção e administração, Departamento de Medicina, .,Cargo ou função, Coordenador de Programa.

1972 - 1989

Leiden University

Vínculo: Servidor Público, Enquadramento Funcional: Professor titular, Carga horária: 40

Atividades

  • 01/1972 - 01/1989

    Direção e administração, Leiden University, .,Cargo ou função, Chefe de Departamento.

Criando um monitoramento

Nossos robôs irão buscar nos nossos bancos de dados todos os processos de Peter Lees Pearson e sempre que o nome aparecer em publicações dos Diários Oficiais, avisaremos por e-mail e pelo painel do usuário

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continuar

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Criando um monitoramento

Nossos robôs irão buscar nos nossos bancos de dados todas as movimentações desse processo e sempre que o processo aparecer em publicações dos Diários Oficiais e nos Tribunais, avisaremos por e-mail e pelo painel do usuário

Para criar um monitoramento é preciso estar cadastrado

continuar

15 segundos

para se cadastrar

+ de 900 mil

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