Edward Ziff

Pós-doutorado

Idiomas

Áreas de atuação

Produções bibliográficas

• Wang, J. ; Goffer, Y. ; Xu, D. ; Tukey, D. S. ; Shamir, D. B. ; Eberle, S. E. ; Zou, A. H. ; Blanck, T. J. ; ZIFF, E. . A Single Subanesthetic Dose of Ketamine Relieves Depression-like Behaviors Induced by Neuropathic Pain in Rats. Anesthesiology (Philadelphia) , v. 115, p. 812-821, 2011.

• Restituito, S. ; Khatri, L. ; Ninan, I. ; Mathews, P. M. ; Liu, X. ; Weinberg, R. J. ; ZIFF, E. . Synaptic autoregulation by metalloproteases and gamma-secretase. The Journal of Neuroscience , v. 31, p. 12083-12093, 2011.

• Mahajan, S. S. ; Thai, K. H. ; Chen, K. ; ZIFF, E. . Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing. Neuroscience , v. 189, p. 305-315, 2011.

• Peng, J. ; ZIFF, E. ; Carr, K. D. . Effects of food restriction and sucrose intake on synaptic delivery of AMPA receptors in nucleus accumbens. Synapse (New York, N.Y. Print) , v. 60, p. 1024-1031, 2011.

• Misra, C. ; Restituito, S. ; Ferreira, J. ; Rameau, G. A. ; Fu, J. ; ZIFF, E. . Regulation of synaptic structure and function by palmitoylated AMPA receptor binding protein,. Molecular and Cellular Neurosciences (Print) , v. 43, p. 341-352, 2010.

• Carr, K. D. ; Chau, L. S. ; Cabeza de Vaca, S. ; Gustafson, K. ; Stouffer, M. ; Tukey, D. S. ; Restituito, S. ; ZIFF, E. . AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats. Neuroscience , v. 165, p. 1074-1086, 2010.

• Akaneya, Y. ; Sohya, K. ; Kitamura, A. ; Washburn, C. ; Zhou, R. ; Ninan, I. ; Tsumoto, T. ; ZIFF, E. . Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development. Plos One , v. 5, p. e12486, 2010.

• Serulle, Y. ; Arancio, O. ; ZIFF, E. . A role for cGMP-dependent protein kinase II in AMPA receptor trafficking and synaptic plasticity. CHANNELS , v. 2, p. 230-232, 2008.

• States, B. ; Khatri, L. ; ZIFF, E. . Stable synaptic retention of serine-880-phosphorylated GluR2 in hippocampal neurons. Molecular and Cellular Neurosciences (Print) , v. 38, p. 189-202, 2008.

• Serulle, Y. ; Zhang, S. ; Ninan, I. ; Puzzo, D. ; McCarthy, M. ; Khatri, L. ; Arancio, O. ; ZIFF, E. . A GluR1-cGKII interaction regulates AMPA receptor trafficking. Neuron (Cambridge, Mass.) , v. 56, p. 670-688, 2007.

• Rameau, G. A. ; Tukey, D. S. ; Garcin-Hosfield, E. D. ; Titcombe, R. F. ; Misra, C. ; Khatri, L. ; Getzoff, E. D. ; ZIFF, E. . Biphasic coupling of neuronal nitric oxide synthase phosphorylation to the NMDA receptor regulates AMPA receptor trafficking and neuronal cell death. The Journal of Neuroscience , v. 27, p. 3445-3455, 2007.

• Silverman, J. ; Restituito, S. ; Lu, W. ; Lee-Edwards, L. ; ZIFF, E. . Synaptic anchorage of AMPA receptors by cadherins through neural plakophilin-related arm protein AMPA receptor-binding protein complexes. The Journal of Neuroscience , v. 27, p. 8505-8516, 2007.

• ZIFF, E. . TARPs and the AMPA receptor trafficking paradox. Neuron (Cambridge, Mass.) , v. 53, p. 627-633, 2007.

• Mahajan, S. S. ; ZIFF, E. . Novel toxicity of the unedited GluR2 AMPA receptor subunit dependent on surface trafficking and increased Ca2+-permeability. Molecular and Cellular Neurosciences (Print) , v. 35, p. 470-481, 2007.

• Jordan, B. A. ; Fernholz, B. D. ; Khatri, L. ; ZIFF, E. . Activity-dependent AIDA-1 nuclear signaling regulates nucleolar numbers and protein synthesis in neurons. Nature Neuroscience (Print) , v. 10, p. 427-435, 2007.

• Greger, I. H. ; ZIFF, E. ; Penn, A. C. . Molecular determinants of AMPA receptor subunit assembly. Trends in Neurosciences (Regular ed.) , v. 30, p. 407-413, 2007.

• Lu, W. ; ZIFF, E. . PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking. Neuron (Cambridge, Mass.) , v. 47, p. 407-421, 2007.

• Nystedt, J. M. ; Brandt, A. ; Vilim, F. S. ; ZIFF, E. ; Panula, P. . Identification of transcriptional regulators of neuropeptide FF gene expression. Peptides (New York, N.Y. 1980) , v. 27, p. 1020-1035, 2006.

• Monea, S. ; Jordan, B. A. ; Srivastava, S. ; DeSouza, S. ; ZIFF, E. . Membrane localization of membrane type 5 matrix metalloproteinase by AMPA receptor binding protein and cleavage of cadherins. The Journal of Neuroscience , v. 26, p. 2300-2312, 2006.

• Jordan, B. A. ; ZIFF, E. . Getting to synaptic complexes through systems biology. Genome Biology (Cessou em 2005) , v. 7, p. 214, 2006.

• Greger, I. H. ; Akamine, P. ; Khatri, L. ; ZIFF, E. . Developmentally regulated, combinatorial RNA processing modulates AMPA receptor biogenesis. Neuron (Cambridge, Mass.) , v. 51, p. 85-97, 2006.

• Misra, C. ; ZIFF, E. . EphB2 gets a GRIP on the dendritic arbor. Nature Neuroscience (Print) , v. 8, p. 848-850, 2005.

• Rameau, G. A. ; Chiu, L. Y. ; ZIFF, E. . Bidirectional regulation of neuronal nitric-oxide synthase phosphorylation at serine 847 by the N-methyl-D-aspartate receptor. Journal of Biological Chemistry (Online) , v. 279, p. 14307-14314, 2004.

• Jordan, B. A. ; Fernholz, B. D. ; Boussac, M. ; Xu, C. ; Grigorean, G., ; ZIFF, E. ; Neubert, T. A. . Identification and verification of novel rodent postsynaptic density proteins. Molecular & Cellular Proteomics , v. 3, p. 857-871, 2004.

• Rameau, G. A. ; Chiu, L. Y. ; ZIFF, E. . NMDA receptor regulation of nNOS phosphorylation and induction of neuron death. Neurobiology of Aging , v. 24, p. 1123-1133, 2003.

• Greger, I. H. ; Khatri, L. ; Kong, X. ; ZIFF, E. . AMPA receptor tetramerization is mediated by Q/R editing. Neuron (Cambridge, Mass.) , v. 40, p. 763-774, 2003.

• Fu, J. ; DeSouza, S. ; ZIFF, E. . Intracellular membrane targeting and suppression of Ser880 phosphorylation of glutamate receptor 2 by the linker I-set II domain of AMPA receptor-binding protein. The Journal of Neuroscience , v. 23, p. 7592-75601, 2003.

• Nystedt, J. M. ; Brandt, A. ; Mandelin, J. ; Vilim, F. S. ; ZIFF, E. ; Panula, P. . Analysis of human neuropeptide FF gene expression. Journal of Neurochemistry , v. 1330, p. 1330-1342, 2002.

• Hanley, J. G. ; Khatri, L. ; Hanson, P. I. ; ZIFF, E. . NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex. Neuron (Cambridge, Mass.) , v. 34, p. 53-67, 2002.

• Greger, I. H. ; Khatri, L. ; ZIFF, E. . RNA editing at arg607 controls AMPA receptor exit from the endoplasmic reticulum. Neuron (Cambridge, Mass.) , v. 34, p. 759-772, 2002.

• Gabriel, R. ; DeSouza, S. ; ZIFF, E. ; Witkovsky, P. . Association of the AMPA receptor-related postsynaptic density proteins GRIP and ABP with subsets of glutamate-sensitive neurons in the rat retina. Journal of Comparative Neurology (1911) , v. 449, p. 129-140, 2002.

• DeSouza, S. ; Fu, J. ; States, B. ; ZIFF, E. . Differential palmitoylation directs the AMPA receptor-binding protein ABP to spines or to intracellular clusters. The Journal of Neuroscience , v. 22, p. 3493-3503, 2002.

• Daly, C. ; ZIFF, E. . Ca2+-dependent formation of a dynamin-synaptophysin complex: potential role in synaptic vesicle endocytosis. The Journal of Biological Chemistry (Print) , v. 277, p. 9010-9015, 2002.

• Barry, M. F. ; ZIFF, E. . Receptor trafficking and the plasticity of excitatory synapses. Current Opinion in Neurobiology , v. 12, p. 279-286, 2002.

• DeSouza, S. ; ZIFF, E. . AMPA receptors do the electric slide. SCI SIGNAL , v. 45, p. 45, 2002.

• Perez, J. L. ; Khatri, L. ; Chang C. ; Srivastava, S. ; Osten P. ; ZIFF, E. . PICK1 targets activated protein kinase Calpha to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. The Journal of Neuroscience , v. 21, p. 5417-5428, 2001.

• Hornyak T. J. ; Hayes D. J. ; Chiu, L. Y. ; ZIFF, E. . Transcription factors in melanocyte development: distinct roles for Pax-3 and Mitf. Mechanisms of Development , v. 101, p. 47-59, 2001.

• Burette, A. ; Khatri, L. ; Wyszynski, M. ; Sheng, M. ; ZIFF, E. . Differential cellular and subcellular localization of ampa receptor-binding protein and glutamate receptor-interacting protein. The Journal of Neuroscience , v. 21, p. 495-503, 2001.

• Weiner, H. L. ; Hyang, H. ; Zagzag, D. ; Boyce, H. ; Lichtenbaum, R. ; ZIFF, E. . Consistent and selective expression of the discoidin domain receptor-1 tyrosine kinase in human brain tumors. Neurosurgery , v. 47, p. 1400-1409, 2000.

• Osten P. ; Khatri, L. ; Perez, J. L. ; Kohr, G. ; Giese, G. ; Daly, C. ; Schulz, T. W. ; Wensky, A. ; Lee-Edwards, L. ; ZIFF, E. . Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor. Neuron (Cambridge, Mass.) , v. 27, p. 313-325, 2000.

• Hornyak T. J. ; Hayes D. J. ; ZIFF, E. . Cell-density-dependent regulation of expression and glycosylation of dopachrome tautomerase/tyrosinase-related protein-2. Journal of Investigative Dermatology , v. 115, p. 106-112, 2000.

• Hornyak T. J. ; Gavin, J. ; Jiao, Z. ; ZIFF, E. . Microphthalmia and loss of coat pigmentation from transgenic expression of a neurogenic factor in pigment cell precursors. Journal of Investigative Dermatology , v. 115, p. 332, 2000.

• Daly, C. ; Sugimori, M. ; Moreira, J. ; ZIFF, E. . Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles. Proceedings of the National Academy of Sciences of the United States of America , v. 97, p. 6120-6125, 2000.

• Rameau, G. A. ; Akaneya, Y. ; Chiu, L. ; ZIFF, E. . Role of NMDA receptor functional domains in excitatory cell death. Neuropharmacology , v. 39, p. 2255-2266, 2000.

• ZIFF, E. . Recent excitement in the ionotropic glutamate receptor field. Annals of the New York Academy of Sciences , v. 868, p. 465-473, 1999.

• Vilim, F. S. ; Aarnisalo, A. A. ; Nieminen, M. L. ; Lintunen, M. ; Karlstedt, K. ; Kontinen, V. K. ; Kalso, E. ; States, B. ; Panula, P. ; ZIFF, E. . Gene for pain modulatory neuropeptide NPFF: induction in spinal cord by noxious stimuli. Molecular Pharmacology (Print) , v. 55, p. 804-811, 1999.

• Srivastava, S. ; ZIFF, E. . ABP: a novel AMPA receptor binding protein. Annals of the New York Academy of Sciences , v. 868, p. 561-564, 1999.

• Osten P. ; ZIFF, E. . AMPA receptor forms a biochemically functional complex with NSF and alpha- and beta-SNAPs. Annals of the New York Academy of Sciences , v. 868, p. 558-560, 1999.

• Lee, T. C. ; ZIFF, E. . Mxi1 is a repressor of the c-Myc promoter and reverses activation by USF. The Journal of Biological Chemistry (Print) , v. 274, p. 595-606, 1999.

• Boxer, A. L. ; Moreno, H. ; Rudy, B. ; ZIFF, E. . FGF-2 potentiates Ca(2+)-dependent inactivation of NMDA receptor currents in hippocampal neurons. Journal of Neurophysiology , v. 82, p. 3367-3377, 1999.

• Osten P. ; Srivastava, S. ; Inman, G. J. ; Vilim, F. S. ; Khatri, L. ; Lee, L. M. ; States, B. ; Einheber, S. ; Milner, T. A. ; Hanson, P. I. ; ZIFF, E. . Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP. Neuron (Cambridge, Mass.) , v. 21, p. 581-591, 1998.

• Issack, P. S. ; ZIFF, E. . Genetic elements regulating HES-1 induction in Wnt-1-transformed PC12 cells. Cell Growth and Differentiation , v. 9, p. 827-836, 1998.

• Issack, P. S. ; ZIFF, E. . Altered expression of helix-loop-helix transcriptional regulators and cyclin D1 in Wnt-1-transformed PC12 cells. Cell Growth and Differentiation , v. 9, p. 837-845, 1998.

• Ghee, M. ; Baker, H. ; Miller, J. C. ; ZIFF, E. . AP-1, CREB and CBP transcription factors differentially regulate the tyrosine hydroxylase gene. Molecular Brain Research (Cessou em 2005) , v. 55, p. 101-114, 1998.

• Osten P. ; Srivastava, S. ; Inman, G. J. ; Vilim, F. S. ; Khatri, L. ; Lee, L. M. ; States, B. ; Einheber, S. ; Milner, T. A. ; Hanson, P. I. ; ZIFF, E. . The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs. Neuron (Cambridge, Mass.) , v. 21, p. 99-110, 1998.

• ZIFF, E. . Enlightening the postsynaptic density. Neuron (Cambridge, Mass.) , v. 19, p. 1163-1174, 1997.

• Yan, G. Z. ; ZIFF, E. . Nerve growth factor induces transcription of the p21 WAF1/CIP1 and cyclin D1 genes in PC12 cells by activating the Sp1 transcription factor. The Journal of Neuroscience , v. 17, p. 6122-6132, 1997.

• Lee, T. C. ; Li, L. ; Philipson, L. ; ZIFF, E. . Myc represses transcription of the growth arrest gene gas1. Proceedings of the National Academy of Sciences of the United States of America , v. 94, p. 12886-12891, 1997.

• Daly, C. ; ZIFF, E. . Post-transcriptional regulation of synaptic vesicle protein expression and the developmental control of synaptic vesicle formation. The Journal of Neuroscience , v. 17, p. 2365-2375, 1997.

• Wong, H. K. ; ZIFF, E. . The human papillomavirus type 16 E7 protein complements adenovirus type 5 E1A amino-terminus-dependent transactivation of adenovirus type 5 early genes and increases ATF and Oct-1 DNA binding activity. Journal of Virology (Print) , v. 70, p. 332-340, 1996.

• Weiner, H. L. ; Rothman, M. ; Miller, D. C. ; ZIFF, E. . Pediatric brain tumors express multiple receptor tyrosine kinases including novel cell adhesion kinases. Pediatric Neurosurgery , v. 25, p. 64-71, 1996.

• MacGregor, D. ; Li, L. H. ; ZIFF, E. . Dominant negative mutants of Myc inhibit cooperation of both Myc and adenovirus serotype-5 E1a with Ras. Journal of Cellular Physiology (Print) , v. 167, p. 95-105, 1996.

• Yan, G. Z. ; ZIFF, E. . NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1. The Journal of Neuroscience , v. 15, p. 6200-6212, 1995.

• Nerlov, C. ; ZIFF, E. . CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells. EMBO Journal (Print) , v. 14, p. 4318-4328, 1995.

• Kerkhoff, E. ; ZIFF, E. . Cyclin D2 and Ha-Ras transformed rat embryo fibroblasts exhibit a novel deregulation of cell size control and early S phase arrest in low serum. EMBO Journal (Print) , v. 14, p. 1892-1903, 1995.

• Kerkhoff, E. ; ZIFF, E. . Deregulated messenger RNA expression during T cell apoptosis. Nucleic Acids Research , v. 23, p. 4857-4863, 1995.

• Jamal, S. ; ZIFF, E. . Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo. Oncogene (Basingstoke) , v. 10, p. 2095-2101, 1995.

• Hopewell, R. ; ZIFF, E. . The nerve growth factor-responsive PC12 cell line does not express the Myc dimerization partner Max. Molecular and Cellular Biology (Print) , v. 15, p. 3470-3478, 1995.

• Hopewell, R. ; Li, L. ; MacGregor, D. ; Nerlov, C. ; ZIFF, E. . Regulation of cell proliferation and differentiation by Myc. Journal of Cell Science , v. 19, p. 85-89, 1995.

• Wong, H. K. ; ZIFF, E. . Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters. Journal of Virology (Print) , v. 68, p. 4910-4920, 1994.

• Ross, D. ; ZIFF, E. . Defective processing of human adenovirus 2 late transcription unit mRNAs during abortive infections in monkey cells. Virology (New York, N.Y. Print) , v. 202, p. 107-115, 1994.

• Nerlov, C. ; ZIFF, E. . Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-alpha on the serum albumin promoter. Genes & Development , v. 8, p. 350-362, 1994.

• Li, L. H. ; Nerlov, C. ; Prendergast, G. ; MacGregor, D. ; ZIFF, E. . c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. EMBO Journal (Print) , v. 13, p. 4070-4079, 1994.

• Gizang-Ginsberg, E. ; ZIFF, E. . Fos family members successively occupy the tyrosine hydroxylase gene AP-1 site after nerve growth factor or epidermal growth factor stimulation and can repress transcription. Molecular Endocrinology (Baltimore, Md.) , v. 8, p. 249-262, 1994.

• Buchkovich, K. J. ; ZIFF, E. . Nerve growth factor regulates the expression and activity of p33cdk2 and p34cdc2 kinases in PC12 pheochromocytoma cells. Molecular Biology of the Cell (Cessou em 2007. Cont. ISSN 1939-4586 Molecular Biology of the Cell (Online)) , v. 5, p. 1225-1241, 1994.

• Ferre-D'Amare, A. R. ; Prendergast, G. C. ; ZIFF, E. ; Burley, S. K. . Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature (London) , v. 363, p. 38-45, 1993.

• Boulukos, K. E. ; ZIFF, E. . Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism. Oncogene (Basingstoke) , v. 8, p. 237-248, 1993.

• Thompson, M. A. ; Lee, E. ; Lawe, D. ; Gizang-Ginsberg, E. ; ZIFF, E. . Nerve growth factor-induced derepression of peripherin gene expression is associated with alterations in proteins binding to a negative regulatory element. Molecular Biology of the Cell (Cessou em 2007. Cont. ISSN 1939-4586 Molecular Biology of the Cell (Online)) , v. 12, p. 2501-2513, 1992.

• Ross, D. ; ZIFF, E. . Defective synthesis of early region 4 mRNAs during abortive adenovirus infections in monkey cells. Journal of Virology (Print) , v. 66, p. 3110-3117, 1992.

• Prendergast, G. C. ; ZIFF, E. . A new bind for Myc. Trends in Genetics (Regular ed.) , v. 8, p. 91-96, 1992.

• Prendergast, G. C. ; Hopewell, R. ; Gorham, B. J. ; ZIFF, E. . Biphasic effect of Max on Myc cotransformation activity and dependence on amino- and carboxy-terminal Max functions. Genes & Development , v. 6, p. 2429-2439, 1992.

• Prendergast, G. C. ; ZIFF, E. . Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science (New York, N.Y.) , v. 251, p. 186-189, 1991.

• Prendergast, G. C. ; ZIFF, E. . Mbh 1: a novel gelsolin/severin-related protein which binds actin in vitro and exhibits nuclear localization in vivo. EMBO Journal (Print) , v. 10, p. 757-766, 1991.

• Prendergast, G. C. ; Lawe, D. ; ZIFF, E. . Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation. Cell (Cambridge) , v. 65, p. 395-407, 1991.

• Metz, R. ; ZIFF, E. . cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription. Genes & Development , v. 5, p. 1754-1766, 1991.

• Metz, R. ; ZIFF, E. . The helix-loop-helix protein rE12 and the C/EBP-related factor rNFIL-6 bind to neighboring sites within the c-fos serum response element. Oncogene (Basingstoke) , v. 6, p. 2165-2178, 1991.

• Gorham, J. D. ; ZIFF, E. ; Baker, H. . Differential spatial and temporal expression of two type III intermediate filament proteins in olfactory receptor neurons. Neuron (Cambridge, Mass.) , v. 7, p. 485-497, 1991.

• ZIFF, E. . Transcription factors: a new family gathers at the cAMP response site. Trends in Genetics (Regular ed.) , v. 6, p. 69-72, 1990.

• Velcich, A. ; ZIFF, E. . Functional analysis of an isolated fos promoter element with AP-1 site homology reveals cell type-specific transcriptional properties. Molecular and Cellular Biology (Print) , v. 10, p. 6273-6282, 1990.

• Siegfried, Z. ; ZIFF, E. . Altered transcriptional activity of c-fos promoter plasmids in v-raf-transformed NIH 3T3 cells. Molecular and Cellular Biology (Print) , v. 10, p. 6073-6078, 1990.

• MacGregor, D. N. ; ZIFF, E. . Elevated c-myc expression in childhood medulloblastomas. Pediatric Research , v. 28, p. 63-68, 1990.

• Lee, T. H. ; Lee, G. W. ; ZIFF, E. ; Vilcek, J. . Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts. Molecular and Cellular Biology (Print) , v. 10, p. 1982-1988, 1990.

• Jamal, S. ; ZIFF, E. . Transactivation of c-fos and beta-actin genes by raf as a step in early response to transmembrane signals. Nature (London) , v. 344, p. 463-466, 1990.

• Gorham, J. D. ; Baker, H. ; Kegler, D. ; ZIFF, E. . The expression of the neuronal intermediate filament protein peripherin in the rat embryo. Molecular Brain Research (Cessou em 2005) , v. 57, p. 235-248, 1990.

• Gizang-Ginsberg, E. ; ZIFF, E. . Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos. Genes & Development , v. 4, p. 477-491, 1990.

• Vosatka, R. J. ; Hermanowski-Vosatka, A. ; Metz, R. ; ZIFF, E. . Dynamic interactions of c-fos protein in serum-stimulated 3T3 cells. Journal of Cellular Physiology (Print) , v. 138, p. 493-502, 1989.

• Velcich, A. ; ZIFF, E. . The adenovirus-5 12S E1a protein, but not the 13S induces expression of the endoA differentiation marker in F9 cells. Oncogene (Basingstoke) , v. 4, p. 707-713, 1989.

• Velcich, A. ; Delli-Bovi, P. ; Mansukhani, A. ; ZIFF, E. ; Basilico, C. . Expression of the K-fgf protooncogene is repressed during differentiation of F9 cells. Oncogene Research , v. 5, p. 31-37, 1989.

• Thompson, M. A. ; ZIFF, E. . Structure of the gene encoding peripherin, an NGF-regulated neuronal-specific type III intermediate filament protein. Neuron (Cambridge, Mass.) , v. 2, p. 1043-1053, 1989.

• Siegfried, Z. ; ZIFF, E. . Transcription activation by serum, PDGF, and TPA through the c-fos DSE: cell type specific requirements for induction. Oncogene (Basingstoke) , v. 4, p. 3-11, 1989.

• Prendergast, G. C. ; ZIFF, E. . DNA-binding motif. Nature (London) , v. 341, p. 392, 1989.

• Kouzarides, T. ; ZIFF, E. . Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding. Nature (London) , v. 340, p. 568-571, 1989.

• Kouzarides, T. ; ZIFF, E. . Behind the Fos and Jun leucine zipper. Cancer Cell , v. 1, p. 71-76, 1989.

• Velcich, A. ; ZIFF, E. . Adenovirus E1a ras cooperation activity is separate from its positive and negative transcription regulatory functions. Molecular and Cellular Biology (Print) , v. 8, p. 2177-2183, 1988.

• Smith, D. H. ; ZIFF, E. . The amino-terminal region of the adenovirus serotype 5 E1a protein performs two separate functions when expressed in primary baby rat kidney cells. Molecular and Cellular Biology (Print) , v. 8, p. 3882-3890, 1988.

• Riabowol, K. T. ; Vosatka, R. J. ; ZIFF, E. ; Lamb, N. J. ; Feramisco, J. R. . Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells. Molecular and Cellular Biology (Print) , v. 8, p. 1670-1676, 1988.

• Leonard, D. G. ; Gorham, J. D. ; Cole, P. ; Greene, L. A. ; ZIFF, E. . A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein. The Journal of Cell Biology , v. 106, p. 181-193, 1988.

• Jones, N. C. ; Rigby, P. W. ; ZIFF, E. . Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses. Genes & Development , v. 2, p. 267-281, 1988.

• Kouzarides, T. ; ZIFF, E. . The role of the leucine zipper in the fos-jun interaction. Nature (London) , v. 336, p. 646-651, 1988.

• Stein, R. W. ; ZIFF, E. . Repression of insulin gene expression by adenovirus type 5 E1a proteins. Molecular and Cellular Biology (Print) , v. 7, p. 1164-1170, 1987.

• Nepveu, A. ; Levine, R. A. ; Campisi, J. ; Greenberg, M. E. ; ZIFF, E. ; Marcu, K. B. . Alternative modes of c-myc regulation in growth factor-stimulated and differentiating cells. Oncogene (Basingstoke) , v. 1, p. 243-250, 1987.

• Leonard, D. G. ; ZIFF, E. ; Greene, L. A. . Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Molecular and Cellular Biology (Print) , v. 7, p. 3156-3167, 1987.

• Greenberg, M. E. ; Siegfried, Z. ; ZIFF, E. . Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro. Molecular and Cellular Biology (Print) , v. 7, p. 1217-1225, 1987.

• Velcich, A. ; Kern, F. G. ; Basilico, C. ; ZIFF, E. . Adenovirus E1a proteins repress expression from polyomavirus early and late promoters. Molecular and Cellular Biology (Print) , v. 6, p. 4019-4025, 1986.

• Greenberg, M. E. ; ZIFF, E. ; Greene, L. A. . Stimulation of neuronal acetylcholine receptors induces rapid gene transcription. Science (New York, N.Y.) , v. 234, p. 80-83, 1986.

• Greenberg, M. E. ; Hermanowski, A. L. ; ZIFF, E. . Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription. Molecular and Cellular Biology (Print) , v. 6, p. 1050-1057, 1986.

• ZIFF, E. . Splicing in adenovirus and other animal viruses. International Review of Cytology (Cessou em 2008) , v. 93, p. 327-358, 1985.

• Velcich, A. ; ZIFF, E. . Adenovirus E1a proteins repress transcription from the SV40 early promoter. Cell (Cambridge) , v. 40, p. 705-716, 1985.

• Smith, D. H. ; Kegler, D. M. ; ZIFF, E. . Vector expression of adenovirus type 5 E1a proteins: evidence for E1a autoregulation. Molecular and Cellular Biology (Print) , v. 5, p. 2684-2696, 1985.

• Greenberg, M. E. ; Greene, L. A. ; ZIFF, E. . Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells. The Journal of Biological Chemistry (Print) , v. 260, p. 14101-14110, 1985.

• Velcich, A. ; ZIFF, E. . Gene regulation: repression of activators. Nature (London) , v. 312, p. 594-595, 1984.

• Stein, R. ; ZIFF, E. . HeLa cell beta-tubulin gene transcription is stimulated by adenovirus 5 in parallel with viral early genes by an E1a-dependent mechanism. Molecular and Cellular Biology (Print) , v. 4, p. 2792-2801, 1984.

• Greenberg, M. E. ; ZIFF, E. . Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (London) , v. 311, p. 433-438, 1984.

• Falvey, E. ; ZIFF, E. . Sequence arrangement and protein coding capacity of the adenovirus type 2 "i" leader. Journal of Virology (Print) , v. 45, p. 185-191, 1983.

• Shaw, A. R. ; ZIFF, E. . Selective inhibition of adenovirus type 2 early region II and III transcription by an anisomycin block of protein synthesis. Molecular and Cellular Biology (Print) , v. 2, p. 789-799, 1982.

• Fraser, N. W. ; Baker, C. C. ; Moore, M. A. ; ZIFF, E. . Poly(A) sites of adenovirus serotype 2 transcription units. Journal of Molecular Biology , v. 155, p. 207-233, 1982.

• Fire, A. ; Baker, C. C. ; Manley, J. L. ; ZIFF, E. ; Sharp, P. A. . In vitro transcription of adenovirus. Journal of Virology (Print) , v. 40, p. 703-719, 1981.

• Baker, C. C. ; ZIFF, E. . Promoters and heterogeneous 5' termini of the messenger RNAs of adenovirus serotype 2. Journal of Molecular Biology , v. 149, p. 189-221, 1981.

• ZIFF, E. . Transcription and RNA processing by the DNA tumour viruses. Nature (London) , v. 287, p. 491-499, 1980.

• Shaw, A. R. ; ZIFF, E. . Transcripts from the adenovirus-2 major late promoter yield a single early family of 3' coterminal mRNAs and five late families. Cell (Cambridge) , v. 22, p. 905-916, 1980.

• Darnell, J. E., Jr. ; ZIFF, E. ; Nevins, J. R. ; Wilson, M. . Variety in the mechanisms of adenovirus gene control. Annals of the New York Academy of Sciences , v. 354, p. 466-471, 1980.

• Baker, C. C. ; ZIFF, E. . Biogenesis, structures, and sites of encoding of the 5' termini of adenovirus-2 mRNAs. Cold Spring Harbor Symposia on Quantitative Biology , v. 44, p. 415-428, 1980.

• Fraser, N. W. ; Nevins, J. R. ; ZIFF, E. ; Darnell, J. E., Jr. . The major late adenovirus type-2 transcription unit: termination is downstream from the last poly(A) site. Journal of Molecular Biology , v. 129, p. 643-656, 1979.

• Evans, R. ; Weber, J. ; ZIFF, E. ; Darnell, J. E., Jr. . Premature termination during adenovirus transcription. Nature (London) , v. 278, p. 367-370, 1979.

• Baker, C. C. ; Herisse, J. ; Courtois, G. ; Galibert, F. ; ZIFF, E. . Messenger RNA for the Ad2 DNA binding protein: DNA sequences encoding the first leader and heterogenity at the mRNA 5' end. Cell (Cambridge) , v. 18, p. 569-580, 1979.

• ZIFF, E. ; Evans, R. M. . Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit. Cell (Cambridge) , v. 15, p. 1463-1475, 1978.

• ZIFF, E. ; Fraser, N. W. . Adenovirus type 2 late mRNA's: structural evidence for 3'-coterminal species. Journal of Virology (Print) , v. 25, p. 897-906, 1978.

• Fraser, N. W. ; ZIFF, E. . RNA structures near poly(A) of adenovirus-2 late messenger RNAs. Journal of Molecular Biology , v. 124, p. 27-31, 1978.

• Darnell, J. E. ; Evans, R. ; Fraser, N. ; Goldberg, S. ; Nevins, J. ; Salditt-Georgieff, M. ; Schwartz, H. ; Weber, J. ; ZIFF, E. . The definition of transcription units for mRNA. Cold Spring Harbor Symposia on Quantitative Biology , v. 42, p. 515-522, 1978.

• Evans, R. M. ; Fraser, N. ; ZIFF, E. ; Weber, J. ; Wilson, M. ; Darnell, J. E. . The initiation sites for RNA transcription in Ad2 DNA. Cell (Cambridge) , v. 12, p. 733-739, 1977.

• Sedat, J. ; ZIFF, E. ; Galibert, F. . Direct determination of DNA nucleotide sequences. Structure of large specific fragments of bacteriophage phiX174 DNA. Journal of Molecular Biology , v. 107, p. 391-416, 1976.

• Air, G. M. ; Blackburn, E. H. ; Coulson, A. R. ; Galibert, F. ; Sanger, F. ; Sedat, J. W. ; ZIFF, E. . Gene F of bacteriophage phiX174. Correlation of nucleotide sequences from the DNA and amino acid sequences from the gene product. Journal of Molecular Biology , v. 107, p. 445-458, 1976.

• Kamen, R. ; Sedat, J. ; ZIFF, E. . Orientation of the complementary strands of polyoma virus DNA with respect to the DNA physical map. Journal of Virology (Print) , v. 17, p. 212-218, 1975.

• Galibert, F. ; Sedat, J. ; ZIFF, E. . Direct determination of DNA nucleotide sequences: structure of a fragment of bacteriophage phiX172 DNA. Journal of Molecular Biology , v. 87, p. 377-407, 1974.

• ZIFF, E. ; Sedat, J. W. ; Galibert, F. . Determination of the nucleotide sequence of a fragment of bacteriophage phiX 174 DNA. Nature: New biology , v. 241, p. 34-37, 1973.

• ZIFF, E. . Benefits and hazards of manipulating DNA. New Scientist (1971) , v. 60, p. 274-275, 1973.

• ZIFF, E. ; Fresco, J. R. . A method for locating 4-thiouridylate in the primary structure of transfer ribonucleic acids. Biochemistry (New York) , v. 8, p. 3242-3248, 1969.

• ZIFF, E. ; Fresco, J. R. . Chemical transformation of 4-thiouracil nucleosides to uracil and cytosine counterparts. Journal of the American Chemical Society (Print) , v. 90, p. 7338-7342, 1968.

• Israel Rosenfield ; ZIFF, E. ; Borin Van Loon . DNA: A Graphic Guide to the Molecule that Shook the World. 2nd. ed. New York: Columbia University Press, 2011. 272p .

Projetos de pesquisa

• 2013 - 2015

  HIV/AIDS Depression and Cognitive Decline: Behavioral Model, Pilot Drug Discovery and Clinical Analysis - Edital Nº 61/2011 - Capes/CNPq - 150.00, Descrição: We propose to carry out coordinated basic and clinical studies of depression and cognitive decline that arise in patients with HIV/AIDS. These pathologies seriously affect patient quality of life and result from the many effects of the virus on the central nervous system (CNS), including the pronounced CNS inflammatory response induced by HIV and the resulting elevation of inflammatory cytokines. The pathologies also arise from the neurotoxic effects of HIV proteins, including the ENV protein, which is expressed at high levels in the HIV/AIDS patient CNS... , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (24) / Mestrado acadêmico: (4) / Doutorado: (1) . , Integrantes: Edward Ziff - Coordenador / Julio Henrique Rosa Croda - Integrante / Candida Aparecida Leite Kassuya - Integrante / Elisabete Castelon Konkiewitz - Integrante / Rosangela Costa Lima - Integrante / Renan D. Iwamoto - Integrante / Ana Claúdia Piccinelli - - Integrante / Diana Figueiredo de Santana Aquino - Integrante., Financiador(es): Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Auxílio financeiro.

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