Muhammad Nawaz

I'm Dr. Muhammad Nawaz. I did my Master in Chemistry, from Deparment of Chemistry, Gomal University D.I.Khan in 2004. For my M.Phil studies, I move to H.E.J Research Institute of Chemistry, University of Karachi, Karachi, Pakistan. To carry out my Ph.D Research, I decided to travel abroad. For this purose, in 2008, I move to Germany and there, I joined the group of Prof. Dr. Peter Langer at Institute of Chemistry, University of Rostock. My Ph.D topic was the "Synthesis of Diarlbenzophenones and Terphenyls based on side-selective Suzuki and Sonogashira cross coupling reactions." After having my Ph.D, in February 2011, I was appointed as a 'Research Professor / Postdoctoral Fellow" at Departmnet of Chemistry, Korea University, Seoul, Korea. After completing my first Postdoc, I was awarded, a superb scholarship from FAPESP (a funding agency in Brazil). Presently, I'm working (on a project funded by FAPESP) as a "Postdoctoral Research Associate" at Institute of Chemistry, University of Sao Paulo, Sao Paulo, Brazil. Here, I'm working on the Total Synthesis of Natural Product, Argutanes A and Argutane B.

Informações coletadas do Lattes em 10/11/2022

Acadêmico

Formação acadêmica

Doutorado em Chemistry

2008 - 2011

Institute of Chemistry, University of Rostock
Título: "Synthesis of Functionalized Benzophenone and Terphenyls Based on Side-selective Suzuki and Sonogashora cross coupling reactions".
Orientador: Prof. Dr. Peter Langer
Bolsista do(a): DAAD.

Mestrado em Chemistry

2001 - 2004

Department of Chemistry, Gomal University, D.I.Khan
Orientador: Dr. Imam Bakhsh Baloch

Mestrado profissional em Chemistry (M.Phil)

2005 - 2007

H.E.J Research Institute of Chemistry, University of Karachi, Pakistan.
Orientador: Prof. Dr. M. Iqbal Choudhary

Formação complementar

2005 - 2006

X-Ray Crystallography Course. , H.E.J Research Institute of Chemistry, University of Karachi, Pakistan.

2005 - 2006

NMR Concept Course. , H.E.J Research Institute of Chemistry, University of Karachi, Pakistan..

2005 - 2006

Organic Synthesis Course. , H.E.J Research Institute of Chemistry, University of Karachi, Pakistan..

Idiomas

Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Alemão

Compreende Razoavelmente, Fala Razoavelmente, Lê Pouco, Escreve Pouco.

Coreano

Compreende Pouco, Fala Pouco, Lê Pouco, Escreve Pouco.

Urdu

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Áreas de atuação

Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica/Especialidade: Síntese Orgânica.

Participação em eventos

National meeting of the "Korean Chemical Society".National meeting. 2011. (Encontro).

International Symposium on Protein Chemistry.Protein Chemistry Symposium. 2007. (Simpósio).

International Symposium on Natural Product Chemistry.Natural Product. 2006. (Simpósio).

Produções bibliográficas

Khera, Rasheed ; Nawaz, Muhammad ; Feist, Holger ; Villinger, Alexander ; Langer, Peter . Synthesis of Functionalized 3,4-Diarylbenzophenones and 2,4-Diarylbenzophenones by Site-Selective Suzuki and Sonogashira Cross-Coupling Reactions of Bis(triflates) of 3,4- and 2,4-Dihydroxybenzophenone. Synthesis (Stuttgart) , v. 2012, p. 219-234, 2012.
Malik, Imran ; Ahmad, Zeeshan ; Reimann, Sebastian ; Nawaz, Muhammed ; Patonay, Tamás ; Langer, Peter . Sonogashira Reactions of 2,3,4,5-Tetrabromofuran: Synthesis of 2,3,4,5-Tetraalkynylfurans, 2,3,5-Trialkynylfurans and 2,5-Dialkynylfurans. Synlett (Stuttgart) , v. 23, p. 1463-1466, 2012.
Ullah, Ihsan ; Nawaz, Muhammad ; Villinger, Alexander ; Langer, Peter . Synthesis of Trifluoromethyl-Substituted Di- and Terphenyls by Site-Selective Suzuki-Miyaura Reactions of 1,4-Dibromo-2-trifluoromethyl-benzene. Synlett (Stuttgart) , v. 2011, p. 1895-1899, 2011.
Nawaz, Muhammad ; Ullah, Ihsan ; Abid, Obaid-Ur-Rahman ; Villinger, Alexander ; Langer, Peter . Synthesis of 2 ,4-Diarylbenzophenones through Site-Selective Suzuki-Miyaura Reactions of Bis(triflates) of 2 ,4-Dihydroxybenzophenones. European Journal of Organic Chemistry (Print) , v. 2011, p. 6670-6684, 2011.
Ullah, Ihsan ; Nawaz, Muhammad ; Villinger, Alexander ; Langer, Peter . Synthesis of 8,9-disubstituted fluoranthenes by domino two-fold Heck/electrocyclization/dehydrogenation of 1,2-dibromoacenaphthylene. Tetrahedron Letters , v. 52, p. 1888-1890, 2011.
Abid, Obaid-Ur-Rahman ; Nawaz, Muhammad ; Ibad, Muhammad Farooq ; Khera, Rasheed Ahmad ; Iaroshenko, Viktor ; Langer, Peter . Synthesis of functionalized arylpyridines and -pyrimidines by domino [4+2]/retro [4+2] cycloadditions of electron-rich dienes with alkynylpyridines and -pyrimidines. Organic & Biomolecular Chemistry , v. 9, p. 2185, 2011.
Nawaz, Muhammad ; Sher, Muhammad ; Langer, Peter . Synthesis of Organosulfur Compounds Based on Cyclocondensation Reactions of 3-Arylthio-1-silyloxy-1,3-butadienes and 1,3-Bis(silyloxy)-1,3-butadienes. Synlett (Stuttgart) , v. 2010, p. 2383-2391, 2010.
Ibad, Muhammad Farooq ; Abid, Obaid-Ur-Rahman ; Adeel, Muhammad ; Nawaz, Muhammad ; Wolf, Verena ; Villinger, Alexander ; Langer, Peter . Synthesis of Highly Functionalized Biaryls by Condensation of 2-Fluoro-1,3-bis(silyloxy) 1,3-Dienes with 3-Cyanochromones and Subsequent Domino Retro-Michael/Aldol/Fragmentation . Journal of Organic Chemistry , v. 75, p. 8315-8318, 2010.
Nawaz, Muhammad ; Khera, Rasheed ; Malik, Imran ; Ibad, Muhammad ; Abid, Obaid-Ur-Rahman ; Villinger, Alexander ; Langer, Peter . Synthesis of 3,4-Diarylbenzophenones by Site-Selective Suzuki-Miyaura Reactions of 3,4-Bis(trifluoromethylsulfonyloxy)benzophenone. Synlett (Stuttgart) , v. 2010, p. 979-981, 2010.
Ullah, Ihsan ; Sher, Muhammad ; Khera, Rasheed Ahmad ; Ali, Asad ; Nawaz, Muhammad ; Shkoor, Mohanad ; Iqbal, Inam ; Imran, Muhammad ; Villinger, Alexander ; Fischer, Christine ; Langer, Peter . Synthesis of of sterically encumbered biaryls based on a `copper(I)-catalyzed arylation/[3+3] cyclocondensation strategy. Tetrahedron (Oxford. Print) , v. 66, p. 3824-3835, 2010.
Ibad, Muhammad ; Abid, Obaid-Ur-Rahman ; Nawaz, Muhammad ; Adeel, Muhammad ; Villinger, Alexander ; Langer, Peter . Synthesis of 3,5-Diaryl-4-fluorophthalates by [4+2]-Cycloaddition and Subsequent Site-Selective Suzuki-Miyaura Reactions. Synlett (Stuttgart) , v. 2010, p. 195-198, 2010.
Abid, Obaid-Ur-Rahman ; Ibad, Muhammad Farooq ; Nawaz, Muhammad ; Ali, Asad ; Sher, Muhammad ; Rama, Nasim Hasan ; Villinger, Alexander ; Langer, Peter . Synthesis of 1,4-diaryl-2-naphthoates based on site-selective Suzuki Miyaura reactions. Tetrahedron Letters , v. 51, p. 1541-1544, 2010.
Nawaz, Muhammad ; Ibad, Muhammad ; Abid, Obaid-Ur-Rahman ; Khera, Rasheed ; Villinger, Alexander ; Langer, Peter . Synthesis of Functionalized p-Terphenyls Based on Site-Selective Suzuki Cross-Coupling Reactions of Bis(triflates) of 2,5-Dihydroxybenzoate. Synlett (Stuttgart) , v. 2010, p. 150-152, 2010.
Abid, Obaid-Ur-Rahman ; Ibad, Muhammad Farooq ; Nawaz, Muhammad ; Adeel, Muhammad ; Rama, Nasim Hasan ; Villinger, Alexander ; Langer, Peter . Synthesis of 3,5-diaryl-4-chlorophthalates by [4+2] cycloaddition of 1-ethoxy-2-chloro-1,3-bis(trimethylsilyloxy)-1,3-diene with dimethyl acetylenedicarboxylate and subsequent site-selective Suzuki Miyaura reactions. Tetrahedron Letters , v. 51, p. 657-660, 2010.
Nawaz, Muhammad ; Adeel, Muhammad ; Ibad, Muhammad ; Langer, Peter . Synthesis of Functionalized 2 ,4-Diarylbenzophenones Based on Site-Selective Suzuki Cross-Coupling Reactions. Synlett (Stuttgart) , v. 2009, p. 2154-2156, 2009.
Adeel, Muhammad ; Nawaz, Muhammad ; Villinger, Alexander ; Reinke, Helmut ; Fischer, Christine ; Langer, Peter . Synthesis of polyketide-type phenols by domino `Michael/retro-Michael/Aldol reactions of 3-formylchromones with silyl enol ethers derived from ethyl 3,5-dioxohexanoate. Tetrahedron (Oxford. Print) , v. 65, p. 4099-4105, 2009.

Projetos de pesquisa

2012 - 2014

"Total Synthesis of Natural Product Argutane A and Argutane B", Descrição: Resumo: Uma proposta para a síntese total das argutanas A e B utilizando como etapa chave uma reação de contração de anel promovida por iodo hipervalente é apresentada. A rota sugerida é bastante convergente e compreende a preparação dos fragmentos leste (2) e oeste (3) a partir de um material de partida comum. A maior seqüência linear terá apenas 10 etapas. Além dessas moléculas, pretendemos obter a bosquiniaquina, o ácido bosquiniaquínico, argutina A e argutina B a partir do intermediário sintético 3. Os produtos naturais serão enviados para os seguintes testes: a) atividade contra linhagens de células tumorais com o Prof. J. E. Carvalho, UNICAMP; b) atividade contra malária com o Prof. Alejandro Miguel Katzin, do ICB-USP; c) atividade contra Leishmaniose com o Prof. Marcelo Dias Baruffi, da FCFRP-USP.. , Situação: Em andamento; Natureza: Pesquisa.

Histórico profissional

Endereço profissional

Institute of Chemistry, University of Sao Paulo, Department of Chemistry, University of Sao Paulo. , Av. Prof. Lineu Prestes, 748, 05508-900 - Sao Paulo, SP - Brasil, URL da Homepage:

Experiência profissional

2012 - Atual

Institute of Chemistry, University of Sao Paulo

Vínculo: Colaborador, Enquadramento Funcional: Postdoctoral Research Associate, Carga horária: 40

2011 - 2012

Korea University

Vínculo: Temporary, Enquadramento Funcional: Research Professor / Postdoctoral Fellow, Carga horária: 40