David Yves Jean-Louis Cappellen

Pós-doutorado

Idiomas

Áreas de atuação

Orientou

Produções bibliográficas

• TOUTAIN, JÉRÔME ; PROCHAZKOVA-CARLOTTI, MARTINA ; CAPPELLEN, DAVID ; JARNE, ANA ; CHEVRET, EDITH ; FERRER, JACKY ; IDRISSI, YAMINA ; PELLUARD, FANNY ; CARLES, DOMINIQUE ; MAUGEY-LAULON, BRIGITTE ; LACOMBE, DIDIER ; HOROVITZ, JACQUES ; MERLIO, JEAN-PHILIPPE ; SAURA, ROBERT ; TIAN, XIUHCUN (CINDY) . Reduced Placental Telomere Length during Pregnancies Complicated by Intrauterine Growth Restriction. Plos One , v. 8, p. e54013, 2013.

• PHAM-LEDARD, ANNE ; CAPPELLEN, DAVID ; MARTINEZ, FABIAN ; VERGIER, BÉATRICE ; BEYLOT-BARRY, MARIE ; MERLIO, JEAN-PHILIPPE . MYD88 Somatic Mutation Is a Genetic Feature of Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type. Journal of Investigative Dermatology , v. 132, p. 2118-2120, 2012.

• VU, PHI YEN ; TOUTAIN, JÉRÔME ; CAPPELLEN, DAVID ; DELRUE, MARIE-ANGE ; DAOUD, HUSSEIN ; MONEIM, AZZA ABD EL ; BARAT, PASCAL ; MONTAUBIN, ORIANNE ; BONNET, FRANÇOISE ; DAI, ZONG QI ; PHILIPPE, CHRISTOPHE ; TRAN, CONG TOAI ; ROORYCK, CAROLINE ; ARVEILER, BENOÎT ; SAURA, ROBERT ; BRIAULT, SYLVAIN ; LACOMBE, DIDIER ; TAINE, LAURENCE . A homozygous balanced reciprocal translocation suggests as a candidate gene for MOMO (macrosomia, obesity, macrocephaly, and ocular abnormalities) syndrome. American Journal of Medical Genetics. Part A , v. 158A, p. 2849-2856, 2012.

• GOES, A. C. S. ; CAPPELLEN, D. Y. J. ; SANTOS JUNIOR, G. C. ; PIROZHKOVA, I. ; LIPINSKI, M. ; VASSETZKY, Y. ; MOURA-GALLO, C. V. . Loop domain organization of the p53 locus in normal and breast cancer cells correlates with the transcriptional status of the p53 and the neighboring genes. Journal of Cellular Biochemistry (Print) , v. 112, p. 2072-2081, 2011.

• Delloye-Bourgeois, C ; Fitamant, J ; Paradisi, A ; CAPPELLEN, D. Y. J. ; Douc-Rasy, S ; Raquin, M.A ; Stupack, D ; Nakagawara, A ; Rousseau, R ; Combaret, V ; Puisieux, A ; Couanet-Valteau, D ; Bénard, J ; Bernet, A ; Mehlen, P . Netrin-1 acts as a survival factor for aggressive neuroblastoma. The Journal of Experimental Medicine , v. 206, p. 833-847, 2009.

• Horvilleur, E ; Bauer, M ; Mergui, X ; Goldschneider, D ; La Motte, A ; Bénard, J ; Douc-Rasy, S ; CAPPELLEN, D. Y. J. . p73α isoforms drive opposite transcriptional and post-transcriptional regulation of MYCN expression in neuroblastoma cells. Nucleic Acids Research , v. 36, p. 4222-4232, 2008.

• CAPPELLEN, D. Y. J. ; Schlange, T ; Bauer, M ; Maurer, F ; Hynes, N.E . Novel c-MYC target genes mediate differential effects on cell proliferation and migration. EMBO Reports (Print) , v. 8, p. 70-76, 2007.

• Bernard-Pierrot, I ; Brams, A ; Dunois-Lardé, C ; Caillault, A ; Gil Diez de Medina, S ; CAPPELLEN, D. Y. J. ; Graf, G ; Thiery, J.P ; Chopin, D ; Ricol, D ; Radvanyi, F . Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b. Carcinogenesis (New York. Print) , v. 27, p. 740-747, 2006.

• Rosty, C ; Aubriot, M.H ; CAPPELLEN, D. Y. J. ; Bourdin, J ; Cartier, I ; Thiery, J.P ; Sastre-Garau, X ; Radvanyi, F . Clinical and biological characteristics of cervical neoplasias with FGFR3 mutation. Molecular Cancer , v. 4, p. 15-15, 2005.

• SUSA, M. ; Luong-Nguyen, N.H ; CAPPELLEN, D. Y. J. ; Zamurovic, N . Human primary osteoclasts: in vitro generation and applications as pharmacological and clinical assay. Journal of Translational Medicine (Online) , v. 2, p. 6-6, 2004.

• Zamurovic, N ; CAPPELLEN, D. Y. J. ; RHONER, D. ; SUSA, M. . Coordinated activation of Notch, Wnt and TGF- signaling pathways in BMP-2 induced osteogenesis: Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity. The Journal of Biological Chemistry (Print) , v. 279, p. 37704-37715, 2004.

• ROULLAND, S. ; LEBAILLY, P. ; ROUSSEL, G. ; BRIAND, M. ; CAPPELLEN, D. Y. J. . BCL-2/JH translocation in peripheral blood lymphocytes of unexposed individuals: lack of seasonal variations in frequency and molecular features. International Journal of Cancer (Print) , v. 104, p. 695-698, 2003.

• CAPPELLEN, D. Y. J. ; Luong-Nguyen, N.H ; BONGIOVANNI, S. ; GRENET, O. ; WANKE, C. ; SUSA, M. . Transcriptional program of mouse osteoclast differentiation governed by the macrophage colony-stimulating factor and the ligand for the receptor activator of NF-B. The Journal of Biological Chemistry (Print) , v. 277, p. 21971-21982, 2002.

• LEFRERE-BELDAT, M. ; CAPPELLEN, D. Y. J. ; DAHER, A. ; Gil Diez de Medina, S ; BESSE, F. ; ABBOU, C. ; Thiery, J.P ; ZAFRANI, E. ; Chopin, D ; Radvanyi, F . p15(INK4b) in bladder carcinomas: decreased expression in superficial tumours. British Journal of Cancer , v. 85, p. 1515-1521, 2001.

• Ricol, D ; CAPPELLEN, D. Y. J. ; MARJOU, E. ; Gil Diez de Medina, S ; GIRAULT, J. ; YOSHIDA, T. ; FERRY, G. ; TUCKER, G. ; POUPON, M. ; Chopin, D ; Thiery, J.P ; Radvanyi, F . Tumour suppressive properties of fibroblast growth factor receptor 2-IIIb in human bladder cancer. Oncogene (Basingstoke) , v. 18, p. 7234-7243, 1999.

• CAPPELLEN, D. Y. J. ; OLIVEIRA, C. ; Ricol, D ; Gil Diez de Medina, S ; Bourdin, J ; Sastre-Garau, X ; Chopin, D ; Thiery, J.P ; Radvanyi, F . Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nature Genetics (Print) , v. 23, p. 18-20, 1999.

• CAPPELLEN, D. Y. J. ; Gil Diez de Medina, S ; Chopin, D ; Thiery, J.P ; Radvanyi, F . Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder. Oncogene (Basingstoke) , v. 14, p. 3059-3066, 1997.

• CAPPELLEN, D. Y. J. ; Bénard, J . Pleiotropic overexpression of multidrug resistance-related genes is correlated to MYCN and Max mRNA accumulation during tumour progression in the IGR-N-91 human neuroblastoma model. International Journal of Cancer (Print) , v. 70, p. 430-436, 1997.

Projetos de pesquisa

• 2009 - Atual

  Identification and molecular and functional analysis of candidate genes in cancers, Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (4) Doutorado: (1) . , Integrantes: David Yves Jean-Louis Cappellen - Integrante / David Yves Jean-Louis Cappellen - Coordenador / VERGIER, BÉATRICE - Integrante / BEYLOT-BARRY, MARIE - Integrante / MERLIO, JEAN-PHILIPPE - Integrante / PROCHAZKOVA-CARLOTTI, MARTINA - Integrante / CHEVRET, EDITH - Integrante / Pierre DUBUS - Integrante.

• 2006 - 2008

  Identification et étude fonctionnelle de gènes et de voies de signalisation de l oncogenèse, Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: / Mestrado profissional: (1) / Doutorado: (2) . , Integrantes: David Yves Jean-Louis Cappellen - Integrante / David Yves Jean-Louis Cappellen - Coordenador / J. Bénard - Integrante / Sétha DOUC-RASY - Integrante.

• 2005 - 2006

  Mécanismes moléculaires de régulation de l expression génique dans les cancers, Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (2) . , Integrantes: David Yves Jean-Louis Cappellen - Integrante / David Yves Jean-Louis Cappellen - Coordenador / Sylvie Galiègue - Integrante.

• 2001 - 2005

  Identification of cofactors and effectors of the c-MYC oncoprotein in carcinomas, Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (1) Doutorado: (1) . , Integrantes: David Yves Jean-Louis Cappellen - Integrante / David Yves Jean-Louis Cappellen - Coordenador / Nancy Elisabeth HYNES - Integrante / Thomas SCHLANGE - Integrante.

• 1999 - 2001

  Transcriptionnal programme and molecular mechanisms of mesenchymal cells differentiation, Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (2) Doutorado: (1) . , Integrantes: David Yves Jean-Louis Cappellen - Integrante / David Yves Jean-Louis Cappellen - Integrante / Mira SUSA - Coordenador.

• 1994 - 1999

  Identification and molecular and functional analysis of candidate genes in bladder carcinomas, Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (3) Doutorado: (2) . , Integrantes: David Yves Jean-Louis Cappellen - Integrante / David Yves Jean-Louis Cappellen - Integrante / J.P. Thiery - Integrante / D. Ricol - Integrante / F. Radvanyi - Coordenador.