Teresa Petersen

Teresa Neves Petersen holds a Diploma (1994) in Biochemical Engineering from the Technical University of Lisbon, Portugal, a master degree from the University of St Andrews, Scotland, and a PhD (2000) in Biophysics from Aalborg University, Denmark. During her PhD she has carried out protein electrostatic and structure/function relationship studies, analyzed large protein structure data sets to derive sequence/structure/function insights (protein data mining), NMR studies and carried out research on the interaction between UV light and proteins. Fluorescence spectroscopy has been a key technology during her studies. During her PhD she worked at the Technical University of Lisbon (IST), University of Trondheim (Magnetic Resonance Center) in Norway, Aalborg University in Denmark, and University of Maryland (Center for Fluorescence Spectroscopy) in USA. As a postdoctoral researcher for 3 years she spent time at Aalborg University and at the Lund Laser Center, Lund University, Sweden where she worked on ultrafast spectroscopy studies on proteins and on the effects of UV light on proteins. In September 2003 Teresa Petersen became an Associate Professor at Aalborg University. In 2004 she established the Ultrafast Biospectroscopy Laser Lab facilities at Aalborg University, a key laser facility in Europe and an associate member of LaserLab Europe. She was the co-founder and Chief Science Advisor of BioNanoPhotonics A/S from 2003-2009, a university owned company that has developed a competitive method for the production of micro-arrays, biofunctionalized nanoparticles and surfaces coated with biomolecules. In 2011, Teresa Petersen became a Principal Investigator at INL, the International Iberian Nanotechnology Laboratory, leading the BioPhotonics group, where her work is focused on the interaction between light and biomolecules, in particular proteins, and its applications in nanomedicine. A main application is the use of light in order to develop a new photonic cancer therapy. Teresa Petersen has a keen interest on the effect of UV light on key pharmaceutical proteins. The BioPhotonics group is part of the Nanomedicine Department.

Informações coletadas do Lattes em 10/11/2022

Acadêmico

Formação acadêmica

Doutorado em Biofísica

1996 - 2000

Aalborg University
Título: The Role of Electrostatic Interactions and Light in Protein Structure and Function
Orientador: XXX
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Mestrado em Biochemistry

1994 - 1994

University of St Andrews
Orientador: Graham Kemp

Graduação em Biochemical Engineering

1989 - 1994

Technical University of Lisbon
Orientador: Helena Pinheiro

Pós-doutorado

2000 - 2003

Pós-Doutorado. , Aalborg University, AALBORG, Dinamarca. , Grande área: Ciências Biológicas / Área: Biologia Geral.

Idiomas

Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Português

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Áreas de atuação

Grande área: Ciências Biológicas / Área: Biofísica.

Organização de eventos

NEVES-PETERSEN, MARIA TERESA . PhD course on Sensing the NanoWorld. 2007. (Outro).

NEVES-PETERSEN, MARIA TERESA . Ph.D. course on Spectroscopy of Nanosize particles and surfaces. Femtobiology, Single Molecule Spectroscopy and Correlation Spectroscopy. 2003. (Outro).

NEVES PETERSEN, MARIA TERESA . Ph.D. Course on Fluorescence Spectroscopy and Fluorescence Microscopy in Biosciences - Methodologies and Applications. 2001. (Outro).

NEVES PETERSEN, MARIA TERESA . Ph.D. Course on Structure, Function and Stability of Lipases. 1999. (Outro).

Produções bibliográficas

CORREIA, MANUEL ; NEVES-PETERSEN, MARIA TERESA ; PARRACINO, ANTONIETTA ; DI GENNARO, ANE KOLD ; PETERSEN, STEFFEN B. . Photophysics, Photochemistry and Energetics of UV Light Induced Disulphide Bridge Disruption in apo-α-Lactalbumin. Journal of Fluorescence , v. 22, p. 323-337, 2012.
PETERSEN, STEFFEN B. ; NEVES-PETERSEN, MARIA TERESA ; HENRIKSEN, SVEND B. ; MORTENSEN, RASMUS J. ; GEERTZ-HANSEN, HENRIK M. ; CSERMELY, PETER . Scale-Free Behaviour of Amino Acid Pair Interactions in Folded Proteins. Plos One , v. 7, p. e41322, 2012.
CORREIA, MANUEL ; NEVES-PETERSEN, MARIA TERESA ; JEPPESEN, PER BENDIX ; GREGERSEN, S REN ; PETERSEN, STEFFEN B. ; SUBRAMANYAM, RAJAGOPAL . UV-Light Exposure of Insulin: Pharmaceutical Implications upon Covalent Insulin Dityrosine Dimerization and Disulphide Bond Photolysis. Plos One , v. 7, p. e50733, 2012.
PARRACINO, ANTONIETTA ; GAJULA, GNANA PRAKASH ; GENNARO, ANE KOLD ; NEVES-PETERSEN, MARIA TERESA ; RAFAELSEN, JENS ; PETERSEN, STEFFEN B. . Towards Nanoscale Biomedical Devices in Medicine: Biofunctional and Spectroscopic Characterization of Superparamagnetic Nanoparticles. Journal of Fluorescence , v. 21, p. 663-672, 2011.
PARRACINO, ANTONIETTA ; GAJULA, GNANA PRAKASH ; DI GENNARO, ANE KOLD ; CORREIA, MANUEL ; NEVES-PETERSEN, MARIA TERESA ; RAFAELSEN, JENS ; PETERSEN, STEFFEN B. . Photonic immobilization of bsa for nanobiomedical applications: creation of high density microarrays and superparamagnetic bioconjugates. Biotechnology and Bioengineering (Print) , v. 108, p. 999-1010, 2011.
FIGUEIRAS, TERESA SOFIA ; NEVES-PETERSEN, MARIA TERESA ; PETERSEN, STEFFEN B. . Activation Energy of Light Induced Isomerization of Resveratrol. Journal of Fluorescence , v. 21, p. 1897-1906, 2011.
HENRIKSEN, SVEND B. ; MORTENSEN, RASMUS J. ; GEERTZ-HANSEN, HENRIK M. ; NEVES-PETERSEN, MARIA TERESA ; ARNASON, OMAR ; SÖRING, JÓN ; PETERSEN, STEFFEN B. ; HASLAM, NIALL JAMES . Hyperdimensional Analysis of Amino Acid Pair Distributions in Proteins. Plos One , v. 6, p. e25638, 2011.
NEVES-PETERSEN, MARIA TERESA ; KLITGAARD, S REN ; SKOVSEN, ESBEN ; PETERSEN, STEFFEN B. ; T MMERAAS, KRISTOFFER ; SCHWACH-ABDELLAOUI, KHADIJA . Biophysical Properties of Phenyl Succinic Acid Derivatised Hyaluronic Acid. Journal of Fluorescence , v. 20, p. 483-492, 2010.
BJ RN PETERSEN, STEFFEN ; KOLD DI GENNARO, ANE ; NEVES-PETERSEN, MARIA TERESA ; SKOVSEN, ESBEN ; PARRACINO, ANTONIETTA . Immobilization of biomolecules onto surfaces according to ultraviolet light diffraction patterns. Applied Optics , v. 49, p. 5344, 2010.
PARRACINO, ANTONIETTA ; NEVES-PETERSEN, MARIA TERESA ; DI GENNARO, ANE KOLD ; PETTERSSON, KIM ; LÖVGREN, TIMO ; PETERSEN, STEFFEN B. . Arraying prostate specific antigen PSA and Fab anti-PSA using light-assisted molecular immobilization technology. Protein Science (Print) , v. 19, p. 1751-1759, 2010.
GAJULA, GNANA PRAKASH ; NEVES-PETERSEN, MARIA TERESA ; PETERSEN, STEFFEN B. . Visualization and quantification of four steps in magnetic field induced two-dimensional ordering of superparamagnetic submicron particles. Applied Physics Letters , v. 97, p. 103103, 2010.
NEVES-PETERSEN, MARIA TERESA ; DUROUX, MEG ; SKOVSEN, ESBEN ; DUROUX, LAURENT ; PETERSEN, STEFFEN B. . Printing Novel Molecular Architectures with Micrometer Resolution Using Light. Journal of Nanoscience and Nanotechnology (Print) , v. 9, p. 3372-3381, 2009.
SKOVSEN, ESBEN ; NEVES-PETERSEN, MARIA TERESA ; KOLD, ANE ; DUROUX, LAURENT ; PETERSEN, STEFFEN B. . Immobilizing Biomolecules Near the Diffraction Limit. Journal of Nanoscience and Nanotechnology (Print) , v. 9, p. 4333-4337, 2009.
NEVES-PETERSEN, MARIA TERESA ; KLITGAARD, S REN ; PASCHER, TORBJORN ; SKOVSEN, ESBEN ; POLIVKA, TOMAS ; YARTSEV, ARKADY ; SUNDSTRÖM, VILLLY ; PETERSEN, STEFFEN B. . Flash Photolysis of Cutinase: Identification and Decay Kinetics of Transient Intermediates Formed upon UV Excitation of Aromatic Residues. Biophysical Journal (Print) , v. 97, p. 211-226, 2009.
GAUDEN, M. ; PEZZELLA, A. ; PANZELLA, L. ; NEVES-PETERSEN, M. T. ; SKOVSEN, E. ; PETERSEN, S. B. ; MULLEN, K. M. ; NAPOLITANO, A. ; D'ISCHIA, M. ; SUNDSTRO'M, V. . Role of Solvent, pH, and Molecular Size in Excited-State Deactivation of Key Eumelanin Building Blocks: Implications for Melanin Pigment Photostability. Journal of the American Chemical Society , v. 130, p. 17038-17043, 2008.
CARVALHO, ANA SOFIA L. ; FERREIRA, BRUNO SOMMER ; NEVES-PETERSEN, MARIA TERESA ; PETERSEN, STEFFEN B. ; AIRES-BARROS, MARIA RAQUEL ; MELO, EDUARDO PINHO . Thermal denaturation of HRPA2: pH-dependent conformational changes. Enzyme and Microbial Technology , v. 40, p. 696-703, 2007.
DUROUX, M. ; DUROUX, L. ; NEVES-PETERSEN, M.T. ; SKOVSEN, E. ; PETERSEN, S.B. . Novel photonic technique creates micrometer resolution protein arrays and provides a new approach to coupling of genes, peptide hormones and drugs to nanoparticle carriers. Applied Surface Science , v. 253, p. 8125-8129, 2007.
NEVES-PETERSEN, MARIA TERESA ; KLITGAARD, S REN ; CARVALHO, ANA SOFIA LEITÃO ; PETERSEN, STEFFEN B. ; AIRES DE BARROS, MARIA RAQUEL ; E MELO, EDUARDO PINHO . Photophysics and Photochemistry of Horseradish Peroxidase A2 upon Ultraviolet Illumination. Biophysical Journal (Print) , v. 92, p. 2016-2027, 2007.
OLSEN, B. B. ; NEVES PETERSEN, MARIA TERESA ; KLITGAARD, S. ; ISSINGER, O. ; PETERSEN, S. B. . UV light blocks EGFR signalling in human cancer cell lines. International Journal of Oncology , v. 30, p. 181, 2007.
CROOKSHANKS, M. ; SKOVSEN, E. ; NEVES-PETERSEN, MARIA TERESA ; DUROUX, L. ; GUREVICH, L. ; PETERSEN, S. B. . Light-induced immobilisation of biomolecules as an attractive alternative to microdroplet dispensing-based arraying. PROTEOMICS , v. 7, p. 1, 2007.
DUROUX, MEG ; GUREVICH, LEONID ; NEVES-PETERSEN, MARIA TERESA ; SKOVSEN, ESBEN ; DUROUX, LAURENT ; PETERSEN, STEFFEN B. . Using light to bioactivate surfaces: A new way of creating oriented, active immunobiosensors. Applied Surface Science , v. 254, p. 1126-1130, 2007.
SKOVSEN, ESBEN ; DUROUX, MEG ; NEVES-PETERSEN, MARIA TERESA ; DUROUX, LAURENT ; BJ'RN PETERSEN, STEFFEN . Molecular Printing Using UV-Assisted Immobilization of Biomolecules. INT J OPTOMECHATRONI , v. 1, p. 383-391, 2007.
SNABE, TORBEN ; R DER, GUSTAV ANDREAS ; NEVES-PETERSEN, MARIA TERESA ; BUUS, S REN ; PETERSEN, STEFFEN BJ RN . Oriented coupling of major histocompatibility complex (MHC) to sensor surfaces using light assisted immobilisation technology. Biosensors & Bioelectronics , v. 21, p. 1553-1559, 2006.
NEVES-PETERSEN, M. T. . Photonic activation of disulfide bridges achieves oriented protein immobilization on biosensor surfaces. Protein Science , v. 15, p. 343-351, 2006.
KLITGAARD, S REN ; NEVES-PETERSEN, M. T. ; PETERSEN, S. B. . Quenchers Induce Wavelength Dependence on Protein Fluorescence Lifetimes. Journal of Fluorescence , v. 16, p. 595-609, 2006.
SNABE, TORBEN ; NEVES-PETERSEN, MARIA TERESA ; PETERSEN, STEFFEN BJ RN . Enzymatic lipid removal from surfaces-lipid desorption by a pH-induced -electrostatic explosion-. Chemistry and Physics of Lipids (Print) , v. 133, p. 37-49, 2005.
THILSING-HANSEN, K. ; NEVES-PETERSEN, M. ; PETERSEN, S. ; NEUENDORF, R. ; AL-SHAMERY, K. ; RUBAHN, H.-G. . Luminescence decay of oriented phenylene nanofibers. Physical Review B , v. 72, p. 115213, 2005.
CARVALHO, ANA SOFIA L. ; SANTOS, ANDREA M. ; NEVES-PETERSEN, MARIA TERESA ; PETERSEN, STEFFEN B. ; AIRES-BARROS, MARIA RAQUEL ; PINHO E MELO, EDUARDO . Conformational states of HRPA1 induced by thermal unfolding: Effect of low molecular weight solutes. Biopolymers , v. 75, p. 173-186, 2004.
CARVALHO, A. S. ; MELO, E. ; NEVES-PETERSEN, M. T. ; PETERSEN, S. B. ; AIRES-BARROS, A. . Formation of a misfolded conformation during refolding of HRPA1 in the presence of calcium. Biochimica et Biophysica Acta (Print) (Cessou em 1963. Desmembrado em 2: ISSN 0926-6526 Biochimica et Biophysica Acta. Specialized Section on Mucoprot , v. 1747, p. 99, 2004.
NILSSON, A. ; NEVES PETERSEN, MARIA TERESA ; JOHANSSON, H. ; JANSSON, J. ; SCHILLEN, K. ; TJERNELD, F. ; PETERSEN, S. B. . Tryptophan-tagged cutinase studied by steady-state fluorescence for understanding of tag interactions in aqueous two-phase systems. Biochimica et Biophysica Acta (Print) (Cessou em 1963. Desmembrado em 2: ISSN 0926-6526 Biochimica et Biophysica Acta. Specialized Section on Mucoprot , v. 1646, p. 57, 2003.
CARVALHO, ANA SOFIA L ; MELO, EDUARDO PINHO E ; FERREIRA, BRUNO SOMMER ; NEVES-PETERSEN, MARIA TERESA ; PETERSEN, STEFFEN B ; AIRES-BARROS, MARIA RAQUEL . Heme and pH-dependent stability of an anionic horseradish peroxidase. Archives of Biochemistry and Biophysics (Print) , v. 415, p. 257-267, 2003.
NEVES-PETERSEN, M. T. ; PETERSEN, S. B. . Protein Electrostatics: A review of the equations and methods used to model electrostatic equations in biomolecules. Applications in Biotechnology. Biotechnology Annual Review , v. 9, p. 315-395, 2003.
NEVES PETERSEN, MARIA TERESA ; GRYCZYNSKI, Z. ; LAKOWICZ, J. ; FOJAN, PETER ; PEDERSEN, S. ; PETERSEN, EVAMARIA I. ; PETERSEN, STEFFEN B . High probability of disrupting a disulphide bridge mediated by an endogenous excited tryptophan residue. Protein Science , v. 11, p. 588, 2002.
PETERSEN, STEFFEN B. ; FOJAN, P. ; PETERSEN, E. I. ; NEVES PETERSEN, MARIA TERESA . The thermal stability of the Fusarium solani pisi cutinase as a function of pH.. Journal of Biomedicine and Biotechnology (Print) , v. 1, p. 1, 2001.
NEVES PETERSEN, MARIA TERESA ; FOJAN, PETER ; PETERSEN, STEFFEN B . How do lipases and esterases work: the electrostatic contribution. Journal of Biotechnology , v. 85, p. 115-147, 2001.
NEVES-PETERSEN, MARIA TERESA ; PETERSEN, EVAMARIA I ; FOJAN, PETER ; NORONHA, MELINDA ; MADSEN, RUNE G ; PETERSEN, STEFFEN B . Engineering the pH-optimum of a triglyceride lipase: from predictions based on electrostatic computations to experimental results. Journal of Biotechnology , v. 87, p. 225-254, 2001.
PETERSEN, M. T. N. ; JONSON, P. H. ; PETERSEN, S. B. . Amino acid neighbours and detailed conformational analysis of cysteines in proteins. Protein Engineering Design and Selection , v. 12, p. 535-548, 1999.
PETERSEN, STEFFEN B. ; HARALD JONSON, PER ; FOJAN, PETER ; PETERSEN, EVAMARIA I. ; NEVES PETERSEN, MARIA TERESA ; HANSEN, SISSEL ; ISHAK, RODNEY J. ; HOUGH, EDWARD . Protein engineering the surface of enzymes. Journal of Biotechnology , v. 66, p. 11-26, 1998.
WIMMER, REINHARD ; OLSSON, MARIA ; NEVES PETERSEN, MARIA TERESA ; HATTI-KAUL, RAJNI ; PETERSEN, STEFFEN B ; MÜLLER, NORBERT . Towards a molecular level understanding of protein stabilization: the interaction between lysozyme and sorbitol1Presented in part at the 13th European Experimental N.M.R. Conference, Paris, May 19-24, 1996.1. Journal of Biotechnology , v. 55, p. 85-100, 1997.
PETERSEN, T. ; MARTEL, P. ; PETERSEN, E. I. ; DRABLOS, F. ; PETERSEN, S. B. . Surface and electrostatics of Cutinases. Methods in Enzymology (Print) , v. 248, p. 130-154, 1997.
Teresa, Maria ; Petersen, Steffen ; Prakash, Gnana . UV Light Effects on Proteins: From Photochemistry to Nanomedicine. Molecular Photochemistry - Various Aspects. 1ed.: InTech, 2012, v. , p. 125-158.
NEVES-PETERSEN, MARIA TERESA ; PARRACINO, A. ; PETERSEN, S. . Using UV light to engineer biosensors for cancer detection: the case of prostate specific antigen.. In: Victor R. Preedy; Vinood Patel. (Org.). Biosensors and Cancer. 1ed.London: Science Publishers, 2012, v. 1, p. 378-394.
PETERSEN, T. ; PETERSEN, S. B. ; GUAJULA, G. P. . Sub-picometer structural information of graphene hidden in a 50pm resolved image. Nanoscale , 2013.
PETERSEN, T. ; GALLOWAY, C. ; KREUZER, M. ; ACIMOVIC, S. ; VOLPE, G. ; CORREIA, M. ; PETERSEN, S. B. ; QUIDANT, R. . Plasmon-assisted delivery of single nano-objects in an optical hot-spot. Nano Letters , 2013.

Projetos de pesquisa

2012 - Atual

A novel approach for tumoral targeted phototherapy: focusing light through scattering, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Teresa Petersen - Coordenador., Financiador(es): Foundation for Science and Technology - Auxílio financeiro.
2009 - Atual

Biomarkers detection and nanoparticle based drug delivery systems: new approaches in nanomedicine, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Teresa Petersen - Coordenador., Financiador(es): Portuguese Research Council - Auxílio financeiro.

Histórico profissional

Endereço profissional

International Iberian Nanotechnology Laboratory, BioPhotonics group. , Avenida Mestre José Veiga s/n, Braga, 4715330 - Braga, - Portugal, Telefone: (351) 25314011, URL da Homepage:

Experiência profissional

2011 - Atual

International Iberian Nanotechnology Laboratory

Vínculo: Servidor Público, Enquadramento Funcional: Principal Investigator, Carga horária: 40

Outras informações:
In 2011, Teresa Petersen became a Principal Investigator at INL, the International Iberian Nanotechnology Laboratory, leading the BioPhotonics group, where her work is focused on the interaction between light and biomolecules, in particular proteins, and its applications in nanomedicine. A main application is the use of light in order to develop a new photonic cancer therapy. Teresa Petersen has a keen interest on the effect of UV light on key pharmaceutical proteins. The BioPhotonics group is part of the Nanomedicine Department.

Atividades

10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa
10/2011
Pesquisa e desenvolvimento , BioPhotonics group, .,Linhas de pesquisa

2005 - Atual

The International Society for Optical Engineering

Vínculo: Membro de comitê assessor, Enquadramento Funcional:

Outras informações:
Program Committee Member from 2004-2010 and 2012-2013 of the conference cited below within the Bios session on SPIE Photonics West meeting (The International Society for Optical Engineering). Info available at http://spie.org/ profile/Maria-Teresa.Neves-Petersen-56350. Single Molecule Spectroscopy and Superresolution Imaging VI 2 February 2013 San Francisco, California, USA Single Molecule Spectroscopy and Superresolution Imaging V 21 January 2012 San Francisco, California, USA Single Molecule Spectroscopy and Imaging III 23 January 2010 San Francisco, California, USA Single Molecule Spectroscopy and Imaging II 24 January 2009 San Jose, California, USA Single Molecule Spectroscopy and Imaging 19 January 2008 San Jose, California, USA Advanced Biomedical and Clinical Diagnostic Systems VI 19 January 2008 San Jose, California, USA Ultrasensitive and Single-Molecule Detection Technologies II 20 January 2007 San Jose, California, USA Advanced Biomedical and Clinical Diagnostic Systems V 20 January 2007 San Jose, California, USA Advanced Biomedical and Clinical Diagnostic Systems IV 21 January 2006 San Jose, California, USA Ultrasensitive and Single-Molecule Detection Technologies 21 January 2006 San Jose, California, USA Advanced Biomedical and Clinical Diagnostic Systems III 22 January 2005 San Jose, CA, USA

2003 - 2009

BioNanoPhotonics A/S

Vínculo: Co-founder, Enquadramento Funcional: Chief Science Advisor, Carga horária: 20

Outras informações:
Chief Science Advisor of BioNanoPhotonics A/S from 2003-2009, a university owned company that has developed a competitive method for the production of micro-arrays, biofunctionalized nanoparticles and surfaces coated with biomolecules.

1997 - 1999

Aalborg University

Vínculo: Celetista, Enquadramento Funcional: Research Assistant, Carga horária: 40

Outras informações:
Associate Professor at the Dept. Phys. and Nanotechnology

1996 - 1997

University Of Trondheim

Vínculo: Celetista, Enquadramento Funcional: Research Assistant, Carga horária: 40

1995 - 1995

Technical University of Lisbon

Vínculo: Celetista, Enquadramento Funcional: Research Assistant, Carga horária: 40