Didier Stien

Possui doutorado em Quimica - Universite Paul Cezanne Aix-Marseille 3 (1997). Atualmente é pesquisador titular - Centre National de la Recherche Scientifique. Tem experiência na área de Química, com ênfase em Produtos Naturais, Espectrometria e Química Orgânica.

Informações coletadas do Lattes em 04/11/2022

Acadêmico

Formação acadêmica

Doutorado em Quimica

1993 - 1997

Universite Paul Cezanne Aix-Marseille 3
Título: Cyclisation d'équivalents asymétriques de radicaux acyle. Synthèse énantiosélective d'alpha-alkyl-cyclopentanones par voie radicalaire
Orientador: Michèle P. Bertrand
com Bolsista do(a): Ministère de la recherche et de l'Enseignement Supérieur, MRES, França. Grande área: Ciências Exatas e da TerraGrande Área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica / Especialidade: Reatividade.

Pós-doutorado

2004

Livre-docência. , Universite des Antiles et de la Guyane, UAG*, França. , Título: La synthèse multi-étapes intégrée aux différents défis scientifiques. De la chimie supportée à la valorisation de la biodiversité., Ano de obtenção: 2004., Palavras-chave: produtos naturais; sintese organica; reatividade., Grande área: Ciências da Saúde, Grande Área: Ciências Exatas e da Terra / Área: Química / Subárea: Produtos Naturais. , Grande Área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica.

1998 - 1999

Pós-Doutorado. , The Pennsylvania State University, PSU, Estados Unidos. , Bolsista do(a): Ministère des Affaires Etrangères (Lavoisier), MAE, França. , Grande área: Ciências Exatas e da Terra, Grande Área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica / Especialidade: Reatividade.

Idiomas

Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Espanhol

Compreende Razoavelmente, Fala Pouco, Lê Bem, Escreve Pouco.

Português

Compreende Bem, Fala Razoavelmente, Lê Bem, Escreve Pouco.

Francês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Áreas de atuação

Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Produtos Naturais.

Grande área: Ciências Exatas e da Terra / Área: Química / Subárea: Química Orgânica.

Grande área: Ciências da Saúde / Área: Farmácia / Subárea: Farmacognosia.

Participação em bancas

Aluno: Milena Kalegari

MIGUEL, O. G.;Stien, Didier; Espindola, Laila S.; CRUZ, A. B.; RODRIGUEZ, J. A. L.; RATTMANN, Y. D.. ABORDAGEM FITOQUÍMICA, AVALIAÇÃO FARMACOLÓGICA, ANTIMICROBIANA E TOXICOLÓGICA DE Rourea induta PLANCH. (CONNARACEAE). 2014. Tese (Doutorado em Ciências Farmacêuticas) - Universidade Federal do Paraná.

Aluno: Charlotte Nirma

Stien, Didier; Eparvier, Véronique; SUZUKI, M. T.; MASSIOT, G.; CALDARELLI, S.; CHAMPY, P.. Les mutualismes insectes sociaux ? micro-organismes : une source d?inspiration pour la recherche de nouveaux composés bioactifs. 2014. Tese (Doutorado em Doutorado em Quimica) - Muséum National d'Histoire Naturelle.

Aluno: Maria Deshayes

Espindola, Laila S.;Stien, Didier; ABAUL, J.; PICHETTE, A.. Contribution à la connaissance chimique et évaluation du potentiel biologique de Ludwigia leptocarpa (Onagracées) des Antilles françaises. 2013. Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane.

Aluno: Jima Nambiath Chandran

Stien, Didier; CALDARELLI, S.; Di BARI, L.; SHINTU, L.; SANTAELLA, C.; CAMPREDON, M.. Development of NMR methodology for the analysis and simplification of complex mixtures. 2013. Tese (Doutorado em Quimica) - Aix-Marseille Université.

Aluno: Marion Rivaud

Stien, Didier; LEWIN, G.; ZHANG, J.; BERNARDES GENISSON, V.; VALENTIN, A.; Jullian, Valérie. Les benzo[c]phénanthridines antipaludiques d?origine naturelle : synthèse d?analogues et étude de leur mode d?action. 2012. Tese (Doutorado em Quimica) - Université Toulouse III Paul Sabatier.

Aluno: Charlie Basset

Stien, Didier; Espindola, Laila S.; MASSIOT, G.; BOLZANI, V. S.; DUPLAIS, CHRISTOPHE. Recherche de composés antifongiques issus de bois durables amazoniens. 2011. Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane.

Aluno: Emeline Houël

Stien, Didier; HOSSAERT, M.; FIGADERE, B.; Eparvier, Véronique; QUILICHINI, A.. Etude de substances bioactives issues de la flore amazonienne. 2011. Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane.

Aluno: Alice M

Stien, Didier; Espindola, Laila S.; MASSIOT, G.; LOPES, N. P.; SA, M. F. G.. S. Rodrigues. Análise e valorização bioinspirada dos metabólitos secundários responsáveis pela durabilidade natural de madeiras exploradas na Guiana Francesa. 2010. Tese (Doutorado em Ciências da Saúde) - Universidade de Brasília.

Aluno: Guillaume Odonne

Stien, Didier; Espindola, Laila S.; VERPOORTE, R.; Bourdy, Geneviève; CARMES, B.. Approche ethnopharmacologique comparative des traitements phytothérapeutiques de la leishmaniose en Amazonie. 2010. Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane.

Aluno: Lorena Carneiro Albernaz

Stien, Didier; Espindola, Laila S.; GRELLIER, P.; PUPO, M. T.; SANTOS, C. A.; MAMBU, L.. Atividades antiparasitárias e antifúngicas de plantas do Cerrado : Spiranthera odoratissima e Diospyros hispida. 2010. Tese (Doutorado em Ciências da Saúde) - Universidade de Brasília.

Aluno: Elodie Courtois

CHAVE, JÉRÔME;Stien, Didier; JACTEL, H.; PUTZ, F. E.; FERDY, J.; LOEUILLE, N.; POORTER, L.. Le parfum de la défense des plantes en forêt amazonienne. 2010. Tese (Doutorado em Ecologia) - Université Toulouse III Paul Sabatier.

Aluno: Mariana Royer

Thibaut, Bernard;Stien, Didier; Beauchêne, Jacques; BARDET, S.; TRIBOULOT, P.; STEVANOVIC, T.; PIZZI, A.. Les molécules responsables de la stabilité des bois : cas des bois tropicaux de Guyane. 2008. Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane.

Aluno: Noha Ghanem

Stien, Didier; Martinez, Jean; GIRALT, E.; MAILLARD, B.. Conception, synthèse et évaluation d?inhibiteurs mixtes des enzymes de conversion de l?angiotensine et de l?endothéline ? Réactifs de piégeage d?acides et d?électrophiles supportés sur ammoniums quaternaires. 2004. Tese (Doutorado em Quimica) - Université Montpellier 2 - Sciences et Techniques.

Orientou

Laure-Anne Peyrat

Nouveaux composés antiviraux (dengue) à partir de plantes actives et de leurs endophytes associés; Início: 2013; Tese (Doutorado em Doutorado em Quimica) - Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique; (Orientador);

Yannick Eveno

Bio- et chimiodiversité de micro-organismes endophytes foliaires; Início: 2013; Tese (Doutorado em Doutorado em Quimica) - Muséum National d'Histoire Naturelle, Agence Nationale de la Recherche; (Orientador);

Layal Fahed

Diversité, analyse métabolomique et valorisation d?huiles essentielles de plantes libanaises; Início: 2012; Tese (Doutorado em Doutorado em Quimica) - Muséum National d'Histoire Naturelle, CNRS Libanais; (Orientador);

Madona Khoury

Préparation, analyse et activités antimicrobiennes d?huiles essentielles de plantes libanaises; Início: 2011; Tese (Doutorado em Doutorado em Quimica) - Muséum National d'Histoire Naturelle, Agence Universitaire de la Francophonie; (Orientador);

Thiago Meirelles Casella

Recherche de composés bioactifs à partir d'endophytes fongiques foliaires : une approche bioinspirée de la découverte de nouveaux composés antifongiques, antibactériens et antibiofilms; Início: 2009; Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane, Ministère de l'Education Nationale et de la Recherche; (Orientador);

Charlotte Nirma

Substances microbiennes anticancéreuses antifongiques et antibactériennes; ; 2014; Tese (Doutorado em Quimica) - Muséum National d'Histoire Naturelle, Centre National de la Recherche Scientifique; Orientador: Didier Stien;

Milena Kalegari

ABORDAGEM FITOQUÍMICA, AVALIAÇÃO FARMACOLÓGICA, ANTIMICROBIANA E TOXICOLÓGICA DE Rourea induta PLANCH; (CONNARACEAE); 2014; Tese (Doutorado em Doutorado em Quimica) - Muséum National d'Histoire Naturelle, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Orientador: Didier Stien;

Charlie Basset

Une approche bioinspirée de la découverte de nouveaux composés antifongiques pour le traitement d?affections dermatologiques humaines; 2011; Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane, União Europeia; Orientador: Didier Stien;

Emeline Houël

Etudes de substances bioactives issues de la flore amazonienne; 2011; Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane, Centre National de la Recherche Scientifique; Orientador: Didier Stien;

Guillaume Odonne

Approche ethnopharmacologique comparative des traitements phytothérapeutiques de la leishmaniose en Amazonie; Application aux communautés Chayahuita (Pérou) et du haut et moyen Oyapock (Guyane française); 2010; Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane, Ministère de l'Education Nationale et de la Recherche; Orientador: Didier Stien;

Alice de Souza Rodrigues

Analyse et valorisation des extractibles responsables de la durabilité naturelle des bois exploités de Guyane Française; 2010; Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane, Ministère de l'Education Nationale et de la Recherche; Orientador: Didier Stien;

Elodie Courtois

Etude des défenses chimiques des plantes contre l?herbivorie; 2010; Tese (Doutorado em Ecologia) - Université Toulouse III Paul Sabatier, Centre National de la Recherche Scientifique; Coorientador: Didier Stien;

Mariana Royer

Les molécules responsables de la stabilité des bois : cas des bois tropicaux de Guyane; ; 2008; Tese (Doutorado em Quimica) - Université des Antilles et de la Guyane, Centre National de la Recherche Scientifique; Coorientador: Didier Stien;

Noha Ghanem

Conception, synthèse et évaluation d?inhibiteurs mixtes des enzymes de conversion de l?angiotensine et de l?endothéline / Réactifs de piégeage d?acides et d?électrophiles supportés sur ammoniums quaternaires; 2004; Tese (Doutorado em Quimica) - Université Montpellier 2 - Sciences et Techniques, Groupe Servier; Orientador: Didier Stien;

Produções bibliográficas

LI, CUI-YU ; MENG, YI-HAN ; YING, ZHE-MING ; XU, NAN ; HAO, DONG ; GAO, MING-ZHE ; ZHANG, WEN-JIE ; XU, LIANG ; GAO, YU-CONG ; Stien, Didier ; YING, XI-XIANG . Correction to Three Novel Alkaloids from L. and Their Anti-inflammatory Effects. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY , v. 65, p. 993-994, 2017.
TOURÉ, SEINDÉ ; NIRMA, CHARLOTTE ; FALKOWSKI, MICHAEL ; DUSFOUR, ISABELLE ; BOULOGNE, ISABELLE ; JAHN-OYAC, ARNAUD ; COKE, MAÏRA ; AZAM, DIDIER ; GIROD, ROMAIN ; MORIOU, CÉLINE ; Odonne, Guillaume ; Stien, Didier ; Houël, Emeline ; Eparvier, Véronique . Larvicidal Sesquiterpene Alkaloids from. JOURNAL OF NATURAL PRODUCTS , v. 80, p. 384-390, 2017.
ANDRÉ, AMANDINE ; WOJTOWICZ, NATHALIE ; TOURÉ, KAATIO ; Stien, Didier ; Eparvier, Véronique . New acorane sesquiterpenes isolated from the endophytic fungus Colletotrichum gloeosporioides SNB-GSS07. TETRAHEDRON LETTERS , v. 58, p. 1269-1272, 2017.
Odonne, Guillaume ; Houël, Emeline ; Bourdy, Geneviève ; Stien, Didier . Treating leishmaniasis in Amazonia: A review of ethnomedicinal concepts and pharmaco-chemical analysis of traditional treatments to inspire modern phytotherapies. JOURNAL OF ETHNOPHARMACOLOGY , v. 199, p. 211-230, 2017.
GIRARD, LÉA ; BLANCHET, ÉLODIE ; INTERTAGLIA, LAURENT ; BAUDART, JULIA ; Stien, Didier ; SUZUKI, MARCELINO ; LEBARON, PHILIPPE ; LAMI, RAPHAËL . Characterization of N-Acyl Homoserine Lactones in Vibrio tasmaniensis LGP32 by a Biosensor-Based UHPLC-HRMS/MS Method. SENSORS , v. 17, p. 906, 2017.
PICANÇO, LEIDE CAROLINE DOS SANTOS ; BITTENCOURT, JOSÉ ADOLFO HOMOBONO MACHADO ; HENRIQUES, SHAYANNE VANESSA CORREIA ; DA SILVA, JULIANE SILVA ; OLIVEIRA, JULIANA MARIA DA SILVA ; RIBEIRO, JOSÉ RENATO ; SANJAY, ANTONY-BABU ; CARVALHO, JOSÉ CARLOS TAVARES ; Stien, Didier ; SILVA, JOCIVÂNIA OLIVEIRA DA . Pharmacological activity of Costus spicatus in experimental Bothrops atrox envenomation. PHARMACEUTICAL BIOLOGY , v. 54, p. 1-8, 2016.
AL HAFI, MONAY ; EL BEYROUTHY, MARC ; OUAINI, NAIM ; Stien, Didier ; RUTLEDGE, DOUGLAS ; CHAILLOU, SYLVAIN . Chemical Composition and Antimicrobial Activity of , , and Growing Wild in Lebanon. CHEMISTRY & BIODIVERSITY , v. 13, p. 555-560, 2016.
Courtois, Elodie A. ; DEXTER, KYLE G. ; PAINE, CHARLES ELIOT TIMOTHY ; Stien, Didier ; ENGEL, JULIEN ; Baraloto, Christopher ; CHAVE, JÉRÔME . Evolutionary patterns of volatile terpene emissions across 202 tropical tree species. Ecology and Evolution , v. 6, p. 2854-2864, 2016.
FAHED, LAYAL ; Stien, Didier ; OUAINI, NAÏM ; Eparvier, Véronique ; EL BEYROUTHY, MARC . Chemical Diversity and Antimicrobial Activity of Essential Oils. CHEMISTRY & BIODIVERSITY , v. 13, p. 591-595, 2016.
VANBELLINGEN, QUENTIN P. ; FU, TINGTING ; BICH, CLAUDIA ; Amusant, Nadine ; Stien, Didier ; DELLA-NEGRA, SERGE ; TOUBOUL, DAVID ; BRUNELLE, ALAIN . Mapping Amsh. wood constituents by submicron resolution cluster-TOF-SIMS imaging. JOURNAL OF MASS SPECTROMETRY , v. 51, p. 412-423, 2016.
PEYRAT, LAURE-ANNE ; Eparvier, Véronique ; EYDOUX, CÉCILIA ; GUILLEMOT, JEAN-CLAUDE ; Stien, Didier ; LITAUDON, MARC . Chemical diversity and antiviral potential in the pantropical Diospyros genus. FITOTERAPIA , v. 112, p. 9-15, 2016.
Houël, Emeline ; NARDELLA, FLORE ; Jullian, Valérie ; Valentin, Alexis ; VONTHRON-SÉNÉCHEAU, CATHERINE ; VILLA, PASCAL ; OBRECHT, ADELINE ; KAISER, MARCEL ; BOURREAU, ELIANE ; Odonne, Guillaume ; FLEURY, MARIE ; Bourdy, Geneviève ; Eparvier, Véronique ; Deharo, Eric ; Stien, Didier . Wayanin and guaijaverin, two active metabolites found in a Psidium acutangulum Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae) antimalarial decoction from the Wayana Amerindians. JOURNAL OF ETHNOPHARMACOLOGY , v. 187, p. 241-248, 2016.
FALKOWSKI, MICHAËL ; JAHN-OYAC, ARNAUD ; FERRERO, EMMA ; ISSALY, JEAN ; Eparvier, Véronique ; GIROD, ROMAIN ; Rodrigues, Alice M. S. ; Stien, Didier ; Houël, Emeline ; DUSFOUR, ISABELLE . Assessment of A Simple Compound-Saving Method To Study Insecticidal Activity of Natural Extracts and Pure Compounds Against Mosquito Larvae. JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION , v. 32, p. 337-340, 2016.
FAHED, LAYAL ; EL BEYROUTHY, MARC ; OUAINI, NAÏM ; Eparvier, Véronique ; Stien, Didier . Isolation and characterization of santolinoidol, a bisabolene sesquiterpene from Achillea santolinoides subsp wilhelmsii (K. Koch) Greuter. TETRAHEDRON LETTERS , v. 57, p. 1892-1894, 2016.
ROLLAND, JEAN LUC ; Stien, Didier ; SANCHEZ-FERANDIN, SOPHIE ; LAMI, RAPHAËL . Quorum Sensing and Quorum Quenching in the Phycosphere of Phytoplankton: a Case of Chemical Interactions in Ecology. JOURNAL OF CHEMICAL ECOLOGY , v. 42, p. 1201-1211, 2016.
KHOURY, MADONA ; Stien, Didier ; Eparvier, Véronique ; OUAINI, NAÏM ; EL BEYROUTHY, MARC . Report on the Medicinal Use of Eleven Lamiaceae Species in Lebanon and Rationalization of Their Antimicrobial Potential by Examination of the Chemical Composition and Antimicrobial Activity of Their Essential Oils. Evidence-based Complementary and Alternative Medicine , v. 2016, p. 1-17, 2016.
NIRMA, CHARLOTTE ; Eparvier, Véronique ; Stien, Didier . Antibacterial Ilicicolinic Acids C and D and Ilicicolinal from Neonectria discophora SNB-CN63 Isolated from a Termite Nest. Journal of Natural Products (Print) , v. 78, p. 159-162, 2015.
Houël, Emeline ; GONZALEZ, GERMAN ; BESSIÈRE, JEAN-MARIE ; Odonne, Guillaume ; Eparvier, Véronique ; Deharo, Eric ; Stien, Didier . Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products. Memórias do Instituto Oswaldo Cruz (Impresso) , v. 110, p. 106-113, 2015.
Houël, Emeline ; FLEURY, MARIE ; Odonne, Guillaume ; NARDELLA, FLORE ; Bourdy, Geneviève ; VONTHRON-SÉNÉCHEAU, CATHERINE ; VILLA, PASCAL ; OBRECHT, ADELINE ; Eparvier, Véronique ; Deharo, Eric ; Stien, Didier . Antiplasmodial and anti-inflammatory effects of an antimalarial remedy from the Wayana Amerindians, French Guiana: Takamalaimë (Psidium acutangulum Mart. ex DC., Myrtaceae). Journal of Ethnopharmacology , v. 166, p. 279-285, 2015.
ANOUHE, JEAN-BAPTISTE SAY ; ADIMA, AUGUSTIN AMISSA ; NIAMKÉ, FLORENCE BOBELÉ ; Stien, Didier ; AMIAN, BRISE KASSI ; BLANDINIÈRES, PIERRE-ALAIN ; VIRIEUX, DAVID ; PIRAT, JEAN-LUC ; KATI-COULIBALY, SERAPHIN ; Amusant, Nadine . Dicorynamine and harmalan-N-oxide, two new β-carboline alkaloids from Dicorynia guianensis Amsh heartwood. Phytochemistry Letters (Print) , v. 12, p. 158-163, 2015.
NIRMA, CHARLOTTE ; Eparvier, Véronique ; Stien, Didier . Reactivation of antibiosis in the entomogenous fungus Chrysoporthe sp. SNB-CN74. JOURNAL OF ANTIBIOTICS , v. 68, p. 586-590, 2015.
SORRES, JONATHAN ; NIRMA, CHARLOTTE ; TOURÉ, SEINDÉ ; Eparvier, Véronique ; Stien, Didier . Two new isopimarane diterpenoids from the endophytic fungus Xylaria sp. SNB-GTC2501. TETRAHEDRON LETTERS , v. 56, p. 4596-4598, 2015.
MANDAVID, HUGUES ; Rodrigues, Alice M. S. ; Espindola, Laila S. ; Eparvier, Véronique ; Stien, Didier . Secondary Metabolites Isolated from the Amazonian Endophytic Fungus Diaporthe sp. SNB-GSS10. JOURNAL OF NATURAL PRODUCTS , v. 78, p. 1735-1739, 2015.
HOUËL, E. ; RODRIGUES, A.M.S. ; JAHN-OYAC, A. ; BESSIÈRE, J.-M. ; Eparvier, V. ; Deharo, E. ; STIEN, D. . antidermatophytic activity of (Linden) Ronse essential oil alone and in combination with azoles. Journal of Applied Microbiology (Print) , v. 116, p. 288-294, 2014.
KHOURY, MADONA ; EL'BEYROUTHY, MARC ; OUAINI, NAÏM ; IRITI, MARCELLO ; Eparvier, Véronique ; Stien, Didier . Chemical Composition and Antimicrobial Activity of the Essential Oil of M. . Growing Wild in Lebanon. Chemistry & Biodiversity (Print) , v. 11, p. 825-830, 2014.
KHOURY, MADONA ; Stien, Didier ; OUAINI, NAÏM ; Eparvier, Véronique ; ARNOLD'APOSTOLIDES, NELLY ; EL'BEYROUTHY, MARC . Chemical Composition and Antimicrobial Activity of the Essential Oil of L. Growing Wild in Lebanon. Chemistry & Biodiversity (Print) , v. 11, p. 1990-1997, 2014.
KALEGARI, MILENA ; GEMIN, CARLOS ALBERTO BRUEL ; ARAÚJO-SILVA, GABRIEL ; BRITO, NAIRA JOSELE NEVES DE ; LÓPEZ, JORGE A. ; OLIVEIRA TOZETTO, SIBELE DE ; DAS GRAÇAS ALMEIDA, MARIA ; MIGUEL, MARILIS DALLARMI ; Stien, Didier ; MIGUEL, OBDULIO GOMES . Chemical composition, antioxidant activity and hepatoprotective potential of Rourea induta Planch. (Connaraceae) against CCl4-induced liver injury in female rats. Nutrition (Burbank, Los Angeles County, Calif.) , v. 30, p. 713-718, 2014.
KALEGARI, MILENA ; CERUTTI, MURILO LUIZ ; MACEDO-JÚNIOR, SÉRGIO JOSÉ ; BOBINSKI, FRANCIANE ; MIGUEL, MARILIS DALLARMI ; Eparvier, Véronique ; SANTOS, ADAIR ROBERTO SOARES ; Stien, Didier ; MIGUEL, OBDULIO GOMES . Chemical composition and antinociceptive effect of aqueous extract from Rourea induta Planch. leaves in acute and chronic pain models. Journal of Ethnopharmacology , v. 153, p. 801-809, 2014.
BITTENCOURT, JOSE ADOLFO HOMOBONO MACHADO ; DE OLIVEIRA, NAYANA KEYLA SEABRA ; CABRAL, MAXWELL SANTOS ; RIBEIRO, JOSE RENATO ; HENRIQUES, SHAYANNE VANESSA CORREIA ; PICANÇO, LEIDE CAROLINE DOS SANTOS ; SANTOS, CLEYDSON BRENO DOS ; Stien, Didier ; CARVALHO, JOSE CARLOS TAVARES ; DA SILVA, JOCIVANIA OLIVEIRA . ANTIOPHIDIAN ACTIVITY OF BROSIMUM GUIANENSE (AUBL) HUBER. American Journal of Pharmacology and Toxicology , v. 9, p. 148-156, 2014.
Odonne, Guillaume ; VALADEAU, CÉLINE ; ALBAN-CASTILLO, JOAQUINA ; Stien, Didier ; SAUVAIN, MICHEL ; Bourdy, Geneviève . Medical ethnobotany of the Chayahuita of the Paranapura basin (Peruvian Amazon). Journal of Ethnopharmacology , v. 146, p. 127-153, 2013.
NIRMA, CHARLOTTE ; Eparvier, Véronique ; Stien, Didier . Antifungal Agents from SNB-CN73 Isolated from a sp. Termite. Journal of Natural Products (Print) , v. 76, p. 988-991, 2013.
CASELLA, THIAGO M. ; Eparvier, Véronique ; MANDAVID, HUGUES ; BENDELAC, AUDREY ; Odonne, Guillaume ; DAYAN, LAURA ; DUPLAIS, CHRISTOPHE ; Espindola, Laila S. ; Stien, Didier . Antimicrobial and cytotoxic secondary metabolites from tropical leaf endophytes: Isolation of antibacterial agent pyrrocidine C from Lewia infectoria SNB-GTC2402. Phytochemistry , v. 96, p. 370-377, 2013.
Basset, Charlie ; Rodrigues, Alice M.S. ; Eparvier, Véronique ; Silva, Maria R.R. ; Lopes, Norberto P. ; Sabatier, Daniel ; Fonty, Emile ; Espindola, Laila S. ; Stien, Didier . Secondary metabolites from Spirotropis longifolia (DC) Baill and their antifungal activity against human pathogenic fungi. Phytochemistry , v. 74, p. 166-172, 2012.
Bertani, Stéphane ; Houël, Emeline ; Jullian, Valérie ; Bourdy, Geneviève ; Valentin, Alexis ; Stien, Didier ; Deharo, Eric . New findings on Simalikalactone D, an antimalarial compound from Quassia amara L. (Simaroubaceae). Experimental Parasitology , v. 130, p. 341-347, 2012.
Royer, Mariana ; Rodrigues, Alice M.S. ; Herbette, Gaëtan ; Beauchêne, Jacques ; Chevalier, Maxime ; Hérault, Bruno ; Thibaut, Bernard ; Stien, Didier . Efficacy of Bagassa guianensis Aubl. extract against wood decay and human pathogenic fungi. International Biodeterioration & Biodegradation , v. 70, p. 55-59, 2012.
Courtois, Elodie A. ; Baraloto, Christopher ; TIMOTHY PAINE, C.E. ; PETRONELLI, PASCAL ; Blandinieres, Pierre-Alain ; Stien, Didier ; HÖUEL, EMELINE ; BESSIÈRE, JEAN-MARIE ; CHAVE, JÉRÔME . Differences in volatile terpene composition between the bark and leaves of tropical tree species. Phytochemistry , v. 82, p. 81-88, 2012.
NIAMKÉ, FLORENCE BOBELÉ ; Amusant, Nadine ; Stien, Didier ; CHAIX, GILLES ; LOZANO, YVES ; KADIO, ADJUMANE AIMÉ ; LEMENAGER, NICOLAS ; GOH, DOREEN ; ADIMA, AUGUSTIN AMISSA ; KATI-COULIBALY, SÉRAPHIN ; JAY-ALLEMAND, CHRISTIAN . 4 ,5 -Dihydroxy-epiisocatalponol, a new naphthoquinone from Tectona grandis L. f. heartwood, and fungicidal activity. International Biodeterioration & Biodegradation , v. 74, p. 93-98, 2012.
NIRMA, C. ; Rodrigues, Alice M. S. ; Basset, Charlie ; CHEVOLOT, L ; GIROD, R. ; Moretti, C. ; STIEN, D. ; DUSFOUR, I. ; Eparvier, V. . Larvicidal activity of isoflavonoids from Muellera frutescens extracts against Aedes aegypti. Natural Product Communications , v. 7, p. 1319-1322, 2012.
Rodrigues, Alice M.S. ; Stien, Didier ; Eparvier, Véronique ; Espindola, Laila S. ; Beauchêne, Jacques ; Amusant, Nadine ; Leménager, Nicolas ; Baudassé, Christine ; RAGUIN, LUCIEN . The wood preservative potential of long-lasting Amazonian wood extracts. International Biodeterioration & Biodegradation , v. 75, p. 146-149, 2012.
Rodrigues, Alice MS ; Amusant, Nadine ; Beauchêne, Jacques ; Eparvier, Véronique ; Leménager, Nicolas ; Baudassé, Christine ; Espindola, Laila S ; Stien, Didier . The termiticidal activity of Sextonia rubra (Mez) van der Werff (Lauraceae) extract and its active constituent rubrynolide. Pest Management Science (Print) , v. n/a, p. n/a-n/a, 2011.
Odonne, G. ; Herbette, G. ; Eparvier, V. ; Bourdy, G. ; Rojas, R. ; Sauvain, M. ; STIEN, D. . Antileishmanial sesquiterpene lactones from Pseudelephantopus spicatus, a traditional remedy from the Chayahuita Amerindians (Peru). Part III. Journal of Ethnopharmacology , v. 137, p. 875-879, 2011.
Odonne, Guillaume ; Berger, Franck ; Stien, Didier ; Grenand, Pierre ; Bourdy, Geneviève . Treatment of leishmaniasis in the Oyapock basin (French Guiana): A K.A.P. survey and analysis of the evolution of phytotherapy knowledge amongst Wayãpi Indians. Journal of Ethnopharmacology , v. n/a, p. n/a-n/a, 2011.
Royer, Mariana ; Stien, Didier ; Beauchêne, Jacques ; Herbette, Gaëtan ; McLean, J. Paul ; Thibaut, Anne ; Thibaut, Bernard . Extractives of the tropical wood wallaba ( Aubl.) as natural anti-swelling agents. Holzforschung (Berlin. Print) , v. 64, p. 211-215, 2010.
Royer, Mariana ; Herbette, Gaëtan ; Eparvier, Véronique ; Beauchêne, Jacques ; Thibaut, Bernard ; Stien, Didier . Secondary metabolites of Bagassa guianensis Aubl. wood: A study of the chemotaxonomy of the Moraceae family. Phytochemistry , v. 71, p. 1708-1713, 2010.
Rodrigues, Alice M. S. ; Theodoro, Phellipe N. E. T. ; Eparvier, Ve?ronique ; Basset, Charlie ; Silva, Maria R. R. ; Beauche?ne, Jacques ; Espi?ndola, Laila S. ; Stien, Didier . Search for Antifungal Compounds from the Wood of Durable Tropical Trees. Journal of Natural Products (Print) , v. 73, p. 1706-1707, 2010.
Odonne, G. ; Bourdy, G. ; Castillo, D. ; Estevez, Y. ; Lancha-Tangoa, A. ; Alban-Castillo, J. ; Deharo, E. ; Rojas, R. ; STIEN, D. ; Sauvain, M. . Ta ta , Huayani: Perception of leishmaniasis and evaluation of medicinal plants used by the Chayahuita in Peru. Part II. Journal of Ethnopharmacology , v. 126, p. 149-158, 2009.
Cachet, N. ; Hoakwie, F. ; Bertani, S. ; Bourdy, G. ; Deharo, E. ; STIEN, D. ; Houel, E. ; Gornitzka, H. ; Fillaux, J. ; Chevalley, S. ; Valentin, A. ; Jullian, V. . Antimalarial Activity of Simalikalactone E, a New Quassinoid from Quassia amara L. (Simaroubaceae). Antimicrobial Agents and Chemotherapy (Print) , v. 53, p. 4393-4398, 2009.
Houël, Emeline ; Bertani, Stéphane ; Bourdy, Geneviève ; Deharo, Eric ; Jullian, Valérie ; Valentin, Alexis ; Chevalley, Séverine ; Stien, Didier . Quassinoid constituents of Quassia amara L. leaf herbal tea. Impact on its antimalarial activity and cytotoxicity. Journal of Ethnopharmacology , v. 126, p. 114-118, 2009.
Courtois, Elodie A. ; Paine, C. E. Timothy ; Blandinieres, Pierre-Alain ; Stien, Didier ; Bessiere, Jean-Marie ; Houel, Emeline ; Baraloto, Christopher ; Chave, Jerome . Diversity of the Volatile Organic Compounds Emitted by 55 Species of Tropical Trees: a Survey in French Guiana. Journal of Chemical Ecology , v. 35, p. 1349-1362, 2009.
LI, M ; ROYER, M ; STIEN, D. ; LECANTE, A ; ROOS, C . Inhibitive effect of sodium eperuate on zinc corrosion in alkaline solutions. Corrosion Science , v. 50, p. 1975-1981, 2008.
BERTANI, S ; HOUEL, E ; BOURDY, G ; STIEN, D ; JULLIAN, V ; LANDAU, I ; DEHARO, E . Quassia amara L. (Simaroubaceae) leaf tea: Effect of the growing stage and desiccation status on the antimalarial activity of a traditional preparation. Journal of Ethnopharmacology , v. 111, p. 40-42, 2007.
ODONNE, G ; BOURDY, G ; BEAUCHENE, J ; HOUEL, E ; STIEN, D ; CHEVOLOT, L ; DEHARO, E . From Tonic-cups to Bitter-cups: Kwasi bita beker from SurinameDetermination, past and present use of an ancient galenic artefact. Journal of Ethnopharmacology , v. 110, p. 318-322, 2007.
RAHALI, H ; STIEN, D . Highly-loaded amphiphilic polyimino resin: quench reagent and solid support for peptide synthesis. Tetrahedron Letters , v. 47, p. 8205-8207, 2006.
BERTANI, S ; HOUEL, E ; STIEN, D ; CHEVOLOT, L ; JULLIAN, V ; GARAVITO, G ; BOURDY, G ; DEHARO, E . Simalikalactone D is responsible for the antimalarial properties of an amazonian traditional remedy made with Quassia amara L. (Simaroubaceae). Journal of Ethnopharmacology , v. 108, p. 155-157, 2006.
Rahali, Houcine ; Ghanem, Noha ; Griffe, Laurent ; Rahali, Rachid ; Stien, Didier . A general approach to the quantification of resin-bound functional groups by NMR. New Journal of Chemistry , v. 28, p. 1344, 2004.
STIEN, D. ; Gastaldi, S. . Design of Polyaromatic Hydrocarbon-Supported Tin Reagents: A New Family of Tin Reagents Easily Removable from Reaction Mixtures. JOURNAL OF ORGANIC CHEMISTRY , v. 69, p. 4464-4470, 2004.
Ghanem, Noha ; Martinez, Jean ; Stien, Didier . Quaternary Ammonium-Supported Scavenger Reagents for Acids and Electrophiles. European Journal of Organic Chemistry , v. 2004, p. 84-89, 2004.
Nouguier, R ; STIEN, D. . Synthesis of (±)- and (?)-botryodiplodin using stereoselective radical cyclizations of acyclic esters and acetals. Tetrahedron. Asymmetry , v. 14, p. 3005-3018, 2003.
GHANEM, N ; MARTINEZ, J ; STIEN, D . A new high-loading water-soluble scavenger for anhydrides, acid chlorides and isocyanates. Tetrahedron Letters , v. 43, p. 1693-1695, 2002.
GASTALDI, S ; STIEN, D . PAH-supported tin hydride: a new tin reagent easily removable from reaction mixtures. Tetrahedron Letters , v. 43, p. 4309-4311, 2002.
Lin, X ; STIEN, D. . Development of efficient new methodology for generation, cyclization and functional trapping of iminyl and amidyl radicals. Tetrahedron (Oxford) , v. 57, p. 8779-8791, 2001.
Gastaldi, S. ; Weinreb, S.M. ; STIEN, D. . Diiodosilane: A Reagent for Mild, Efficient Conversion of Carbamates to Ureas via Isocyanates. Journal of Organic Chemistry , v. 65, p. 3239-3240, 2000.
Lin, X ; STIEN, D. . A mild new procedure for production, cyclization and trapping of amidyl radicals: application to a formal total synthesis of peduncularine. Tetrahedron Letters , v. 41, p. 2333-2337, 2000.
STIEN, D. ; Anderson, G.T. ; Chase, C.E. ; Koh, Y.-h. ; Weinreb, S.M. . Total Synthesis of the Antitumor Marine Sponge Alkaloid Agelastatin A. Journal of the American Chemical Society , v. 121, p. 9574-9579, 1999.
Lin, X. ; STIEN, D. ; Weinreb, S.M. . A New Method for the Generation and Cyclization of Iminyl Radicals via the Hudson Reaction. Organic Letters , v. 1, p. 637-640, 1999.
Nouguier, R ; GASTALDI, S ; STIEN, D ; BERTRAND, M ; RENAUD, P . Intramolecular radical allylation with allylic sulfones A synthesis of (±)-botryodiplodin. Tetrahedron Letters , v. 40, p. 3371-3374, 1999.
Anderson, G.T. ; Chase, C.E. ; Koh, Y.-h. ; STIEN, D. ; Weinreb, S.M. ; Shang, M. . Studies on Total Synthesis of the Cytotoxic Marine Alkaloid Agelastatin A. Journal of Organic Chemistry , v. 63, p. 7594-7595, 1998.
STIEN, D . Chiral acyl radical equivalents: 5-exo cyclization of conformationally constrained 1,3-dioxolanyl radicals. Tetrahedron (Oxford) , v. 54, p. 10779-10788, 1998.
STIEN, D. ; Samy, R. ; Nouguier, R. ; Crich, D. ; Bertrand, M.P. . Designed Chiral Acyl Radical Equivalents. Preparation and Cyclizations of Disymmetrically Substituted 1,3-Dioxabicyclo[4.4.0]decan-2-yl Radicals. Journal of Organic Chemistry , v. 62, p. 275-286, 1997.
Bertrand, M.P. ; Crich, D. ; Nouguier, R. ; Samy, R. ; STIEN, D. . Diastereoselective Cyclizations of 1,3-Dioxan-2-yl Radicals: Chiral Acyl Radical Equivalents. Journal of Organic Chemistry , v. 61, p. 3588-3589, 1996.
Basset, Charlie ; Stien, Didier ; Espindola, Laila S. . Recherche de composés antifongiques issus de bois durables amazoniens. 1. ed. Paris: Presses Académiques Francophones, 2013.
Houël, Emeline ; Stien, Didier ; Bourdy, Geneviève ; Deharo, Eric . Quassinoids: Anticancer and Antimalarial Activities. Natural Products. 1ed.: Springer Berlin Heidelberg, 2013, v. , p. 3775-3802.
Houël, Emeline ; Stien, Didier . Chimie des substances naturelles en Amazonie guyanaise. In: Alain Pavé ; Gaëlle Fornet. (Org.). Amazonie, une aventure scientifique et humaine du CNRS. 1ed.Péronnas: Galaade Editions, 2010, v. , p. 116-119.
STIEN, D. . Synthesis from carbonic acid derivatives. In: S. M. Weinreb. (Org.). Houben-Weyl Science of Synthesis / Compounds with Four and Three Carbon-Heteroatom Bonds / Three Carbon-Heteroatom Bonds: Amides and Derivatives; Peptides; Lactams. 1ed.New York: Thieme, 2005, v. 21, p. 27-41.
GASTALDI, S ; STIEN, D. . tris(phenylthio)phosphine. In: L. A. Paquette. (Org.). Encyclopedia of Reagents for Organic Synthesis. : Wiley, 2005, v. , p. -.
Gastaldi, S. ; STIEN, D. . dimethyl[3-(1-pyrenyl)propyl]stannane. In: L. A. Paquette. (Org.). Encyclopedia of Reagents for Organic Synthesis. : Wiley, 2004, v. , p. -.
STIEN, D. . 9-(2-sulfo)fluorenylmethoxycarbonyl chloride. In: L. A. Paquette. (Org.). Encyclopedia of Reagents for Organic Synthesis. : Wiley, 2003, v. , p. -.
Stien, Didier . Moleculas funcionais de simbioses. 2014. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . Etude et valorisation bio-inspirée des molécules fonctionnelles de symbioses. 2014. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . Evolution of volatile compounds-based defenses against herbivory. 2012. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . Les défenses chimiques des arbres amazoniens. 2011. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . Connaissance et valorisation des défenses chimiques des arbres amazoniens. 2011. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . Bio-inspired approaches to the discovery of active metabolites: an example with long-lasting woods antifungal agents. 2009. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . Tisana de Quassia amara: uma receita da vovó contra a malaria. 2008. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . Total Synthesis of the Cytotoxic Marine Alkaloid Agelastatin A and New Approach to Supported Chemistry. 2003. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . Total Synthesis of the Cytotoxic Marine Alkaloid Agelastatin A and New Supported Synthesis Strategies. 2003. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . The Design and Application of Chiral Auxiliaries for Asymmetric Induction in Radical Cyclizations and Studies on the Total Synthesis of agelastatin A. 1999. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . The Design and Application of Chiral Auxiliaries for Asymmetric Induction in Radical Cyclizations and Studies on the Total Synthesis of agelastatin A. 1999. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . The Design and Application of Chiral Auxiliaries for Asymmetric Induction in Radical Cyclizations and Studies on the Total Synthesis of agelastatin A. 1999. (Apresentação de Trabalho/Conferência ou palestra).
Stien, Didier . The Design and Application of Chiral Auxiliaries for Asymmetric Induction in Radical Cyclizations and Studies on the Total Synthesis of agelastatin A. 1999. (Apresentação de Trabalho/Conferência ou palestra).

Histórico profissional

Endereço profissional

Centre National de la Recherche Scientifique, Observatoire Océanologique de Banyuls-sur-mer. , LBBM, Observatoire Océanologique, av du Fontaulé, França, 66650 - Banyuls-sur-mer, - França - Caixa-postal: 66650, Telefone: (33) 430192476, URL da Homepage:

Experiência profissional

1999 - Atual

Centre National de la Recherche Scientifique

Vínculo: Servidor Público, Enquadramento Funcional: Pesquisador titular, Carga horária: 40

2011 - Atual

Institut de Chimie des Substances Naturelles

Vínculo: Servidor Público, Enquadramento Funcional: Pesquisador titular, responsavel de equipe, Carga horária: 40

2003 - 2011

Université des Antilles et de la Guyane

Vínculo: Pesquisador titular, Enquadramento Funcional: Pesquisador, Carga horária: 40

1999 - 2003

Université Montpellier 2

Vínculo: Professor vistante, Enquadramento Funcional: Professor visitante de quimica

1998 - 1999

Pennsylvania State University

Vínculo: Pesquisador, Enquadramento Funcional: Pesquisador, Carga horária: 40, Regime: Dedicação exclusiva.