Jeffrey Michael Bethony

Possui graduação em Matemática - State University of New York (1985), mestrado em Epidemiologia - State University of New York (1997) e doutorado em Epidemiologia - State University of New York (2000). Atualmente é pesquisador e professor adjunto - George Washington University. Possui também vínculo de Pesquisador Visitante no Centro de Pesquisas René Rachou - FIOCRUZ desde 1997. Tem experiência na área de Medicina, com ênfase em Epidemiologia, atuando principalmente nos seguintes temas: hookworm, helminth infections, shistosoma mansoni, vaccine e ancylostoma caninum.

Informações coletadas do Lattes em 04/11/2022

Acadêmico

Formação acadêmica

Doutorado em Epidemiologia

1997 - 2000

State University of New York
Título: Genetic epidemiology of S.mansoni infection in a rural of Brazil
Orientador: Dr. Aurthur Michalek
Bolsista do(a): National Cancer Institute and National Institute of Health. Palavras-chave: Epidemiologia.Grande área: Ciências Biológicas / Área: Genética / Subárea: Genética Humana e Médica.

Mestrado em Epidemiologia

1995 - 1997

State University of New York
Orientador: Dra Germaine Buck
Bolsista do(a): State University of New York, S.U.N.Y, Estados Unidos.

Graduação em Matemática

1980 - 1985

Binghamton University, New York
Bolsista do(a): State University of New York, S.U.N.Y, Estados Unidos.

Pós-doutorado

2000 - 2002

Pós-Doutorado. , Sourthwest Foundation for Biomedical Research. , Bolsista do(a): National Institute of Health and Fogart International Center. , Grande área: Ciências Biológicas / Área: Imunologia / Subárea: Imunogenética.

Idiomas

Bandeira representando o idioma Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Bandeira representando o idioma Português

Compreende Bem, Fala Bem, Lê Razoavelmente, Escreve Razoavelmente.

Tai

Compreende Bem, Fala Razoavelmente, Lê Pouco, Escreve Razoavelmente.

Áreas de atuação

Grande área: Ciências da Saúde / Área: Medicina / Subárea: Eidemiology/Especialidade: Epidemiology.

Grande área: Ciências da Saúde / Área: Medicina / Subárea: Molecular And Genetic Epidemiology.

Grande área: Ciências da Saúde / Área: Medicina / Subárea: Molecular And Genetic Epidemiology/Especialidade: Clinical Trials.

Orientou

Vanessa Salcedo

Biomarkers in the study of susceptibility to helminth infection; 2003; Dissertação (Mestrado em Public Health) - George Washington University,; Orientador: Jeffrey Michael Bethony;

Hillary Manson

Rates of reinfection with hookworm in Minas Gerais state, Brazil; 2003; Dissertação (Mestrado em Public Health) - George Washington University,; Orientador: Jeffrey Michael Bethony;

Yan Wang

The human antibody response to define Necator americanus antigens; 2003; Dissertação (Mestrado em Public Health) - George Washington University,; Orientador: Jeffrey Michael Bethony;

Lauren Pinzola

Hookworm Infection in Sichuan Province, Peoples Republic of China; 2002; Dissertação (Mestrado em Public Health) - George Washington University,; Orientador: Jeffrey Michael Bethony;

Izabela Gomes Ribeiro

Imunoepidemiologia da resposta de anticorpos a antígenos candidatos a vacina contra ancilostomídeo; 2002; Iniciação Científica; (Graduando em Enfermagem) - FUNDAÇÃO OSWALDO CRUZ/CENTRO DE PESQUISAS RENÉ RACHOU, Fundação de Desenvolvimento e Pesquisa; Orientador: Jeffrey Michael Bethony;

Lisiane Gomes

Imunoepidemiologia da resposta de anticorpos candidatos a vacina contra ancilostomídeo; 2002; Iniciação Científica; (Graduando em Ciências Biológicas) - FUNDAÇÃO OSWALDO CRUZ/CENTRO DE PESQUISAS RENÉ RACHOU, Fundação de Desenvolvimento e Pesquisa; Orientador: Jeffrey Michael Bethony;

Ricardo Fujiwara

Immuno response of canine to defined and crude Ancylostoma caninum antigens; 2003; Orientação de outra natureza; (Biomedicina) - George Washington University, George Washington University; Orientador: Jeffrey Michael Bethony;

Luciana Maria de Oliveira

Imunorregulação em doenças parasitárias: estudo do papel de; 2002; Orientação de outra natureza; (Ciências Biológicas) - FUNDAÇÃO OSWALDO CRUZ/CENTRO DE PESQUISAS RENÉ RACHOU, Fundação de Desenvolvimento e Pesquisa; Orientador: Jeffrey Michael Bethony;

Produções bibliográficas

  • Gaze, Soraya ; Driguez, Patrick ; PEARSON, MARK S. ; MENDES, TIAGO ; Doolan, Denise L. ; TRIEU, ANGELA ; McManus, Donald P. ; Gobert, Geoffrey N. ; Periago, Maria Victoria ; CORREA OLIVEIRA, RODRIGO ; CARDOSO, FERNANDA C. ; OLIVEIRA, GUILHERME ; NAKAJIMA, RIE ; JASINSKAS, AL ; HUNG, CHRIS ; LIANG, LI ; PABLO, JOZELYN ; Bethony, Jeffrey M. ; FELGNER, PHILIP L. ; Loukas, Alex . An Immunomics Approach to Schistosome Antigen Discovery: Antibody Signatures of Naturally Resistant and Chronically Infected Individuals from Endemic Areas. PLoS Pathogens (Online) , v. 10, p. e1004033, 2014.

  • AKA, PETER ; EMMANUEL, BENJAMIN ; VILA, MARIA CANDIDA ; JARIWALA, AMAR ; NKRUMAH, FRANCIS ; Periago, Maria V. ; NEEQUAYE, JANET ; KIRUTHU, CHRISTINE ; LEVINE, PAUL H. ; BIGGAR, ROBERT J. ; BHATIA, KISHOR ; Bethony, Jeffrey M. ; MBULAITEYE, SAM M. . Elevated serum levels of interleukin-6 in endemic Burkitt lymphoma in Ghana. Hematological Oncology (Print) , v. na, p. n/a-n/a, 2014.

  • Plieskatt, Jordan L ; Rinaldi, Gabriel ; FENG, YANJUNG ; LEVINE, PAUL H ; EASLEY, SAMANTHA ; MARTINEZ, ELIZABETH ; HASHMI, SALMAN ; SADEGHI, NADER ; Brindley, Paul J ; Bethony, Jeffrey M ; MULVENNA, JASON P . Methods and matrices: approaches to identifying miRNAs for Nasopharyngeal carcinoma. Journal of Translational Medicine (Online) , v. 12, p. 3, 2014.

  • PLIESKATT, J. L. ; DEENONPOE, R. ; MULVENNA, J. P. ; KRAUSE, L. ; SRIPA, B. ; Bethony, J. M. ; BRINDLEY, P. J. . Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome. The FASEB Journal (Online) , v. 27, p. 4572-4584, 2013.

  • Hotez, Peter J. ; Diemert, David ; BACON, KRISTINA M. ; BEAUMIER, COREEN ; Bethony, Jeffrey M. ; Bottazzi, Maria Elena ; Brooker, Simon ; COUTO, ARTUR ROBERTO ; DA SILVA FREIRE, MARCOS ; HOMMA, AKIRA ; LEE, BRUCE Y. ; Loukas, Alex ; LOBLACK, MARVA ; MOREL, CARLOS MEDICIS ; OLIVEIRA, RODRIGO CORREA ; RUSSELL, PHILIP K. . The Human Hookworm Vaccine. Vaccine (Guildford) , v. 31, p. B227-B232, 2013.

  • SAICHUA, PRASERT ; Sithithaworn, Paiboon ; JARIWALA, AMAR R. ; DEIMERT, DAVID J. ; SITHITHAWORN, JIRAPORN ; Sripa, Banchob ; Laha, Thewarach ; Mairiang, Eimorn ; Pairojkul, Chawalit ; Periago, Maria Victoria ; KHUNTIKEO, NARONG ; Mulvenna, Jason ; Bethony, Jeffrey M. . Microproteinuria during Opisthorchis viverrini Infection: A Biomarker for Advanced Renal and Hepatobiliary Pathologies from Chronic Opisthorchiasis. PLoS Neglected Tropical Diseases (Online) , v. 7, p. e2228, 2013.

  • AKA, P. ; VILA, M. C. ; Jariwala, A. ; NKRUMAH, F. ; EMMANUEL, B. ; YAGI, M. ; PALACPAC, N. M. Q. ; PERIAGO, M. V. ; NEEQUAYE, J. ; KIRUTHU, C. ; TOUGAN, T. ; LEVINE, P. H. ; BIGGAR, R. J. ; PFEIFFER, R. M. ; BHATIA, K. ; HORII, T. ; Bethony, J. M. ; MBULAITEYE, S. M. . Endemic Burkitt lymphoma is associated with strength and diversity of Plasmodium falciparum malaria stage-specific antigen antibody response. Blood (Philadelphia. Online) , v. na, p. na, 2013.

  • Geiger, Stefan M. ; Jardim-Botelho, Anne ; WILLIAMS, WESTON ; Alexander, Neal ; Diemert, David J. ; Bethony, Jeffrey M. . Serum CCL11 (eotaxin-1) and CCL17 (TARC) are serological indicators of multiple helminth infections and are driven by Schistosoma mansoni infection in humans. TM & IH. Tropical Medicine and International Health (Print) , v. 00, p. n/a-n/a, 2013.

  • MATHIAS, D. K. ; PLIESKATT, J. L. ; ARMISTEAD, J. S. ; Bethony, J. M. ; ABDUL-MAJID, K. B. ; MCMILLAN, A. ; ANGOV, E. ; ARYEE, M. J. ; Zhan, B. ; Gillespie, P. ; Keegan, B. ; JARIWALA, A. R. ; REZENDE, W. ; Bottazzi, M. E. ; SCORPIO, D. G. ; Hotez, P. J. ; DINGLASAN, R. R. . Expression, Immunogenicity, Histopathology, and Potency of a Mosquito-Based Malaria Transmission-Blocking Recombinant Vaccine. Infection and Immunity (Print) , v. 80, p. 1606-1614, 2012.

  • Gaze, Soraya ; MCSORLEY, HENRY J. ; DAVESON, JAMES ; JONES, DI ; Bethony, Jeffrey M. ; OLIVEIRA, LUCIANA M. ; SPEARE, RICHARD ; McCarthy, James S. ; ENGWERDA, CHRISTIAN R. ; CROESE, JOHN ; Loukas, Alex . Characterising the Mucosal and Systemic Immune Responses to Experimental Human Hookworm Infection. PLoS Pathogens (Online) , v. 8, p. e1002520, 2012.

  • PEARSON, MARK S. ; PICKERING, DARREN A. ; MCSORLEY, HENRY J. ; Bethony, Jeffrey M. ; Tribolet, Leon ; DOUGALL, ANNETTE M. ; Hotez, Peter J. ; Loukas, Alex . Enhanced Protective Efficacy of a Chimeric Form of the Schistosomiasis Vaccine Antigen Sm-TSP-2. PLoS Neglected Tropical Diseases (Online) , v. 6, p. e1564, 2012.

  • YONGLITTHIPAGON, PONLAPAT ; Pairojkul, Chawalit ; CHAMGRAMOL, YAOVALUX ; Loukas, Alex ; Mulvenna, Jason ; Bethony, Jeffrey ; BHUDHISAWASDI, VAJARABHONGSA ; Sripa, Banchob . Prognostic significance of peroxiredoxin 1 and ezrin-radixin-moesin binding phosphoprotein 50 in cholangiocarcinoma. Human Pathology (Print) , v. 43, p. 1719-1730, 2012.

  • Mulvenna, Jason ; YONGLITTHIPAGON, PONLAPAT ; Sripa, Banchob ; Brindley, Paul J. ; Loukas, Alex ; Bethony, Jeffrey M. . Banking on the future: Biobanking for omics approaches to biomarker discovery for Opisthorchis-induced cholangiocarcinoma in Thailand. Parasitology International (Print) , v. 61, p. 173-177, 2012.

  • Sripa, Banchob ; Thinkhamrop, Bandit ; Mairiang, Eimorn ; Laha, Thewarach ; Kaewkes, Sasithorn ; Sithithaworn, Paiboon ; Periago, Maria Victoria ; BHUDHISAWASDI, VAJARABHONGSA ; YONGLITTHIPAGON, PONLAPAT ; Mulvenna, Jason ; Brindley, Paul J. ; Loukas, Alex ; Bethony, Jeffrey M. . Elevated Plasma IL-6 Associates with Increased Risk of Advanced Fibrosis and Cholangiocarcinoma in Individuals Infected by Opisthorchis viverrini. PLoS Neglected Tropical Diseases (Online) , v. 00, p. 00-00, 2012.

  • Diemert, David J. ; PINTO, ANTONIO G. ; FREIRE, JANAINA ; JARIWALA, AMAR ; SANTIAGO, HELTON ; HAMILTON, ROBERT G. ; Periago, Maria Victoria ; Loukas, Alex ; Tribolet, Leon ; Mulvenna, Jason ; Correa-Oliveira, Rodrigo ; Hotez, Peter J. ; Bethony, Jeffrey M. . Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: Implications for the development of vaccines against helminths. Journal of Allergy and Clinical Immunology , v. 130, p. 169-176.e6, 2012.

  • PEARSON, MARK S. ; Tribolet, Leon ; CANTACESSI, CINZIA ; Periago, Maria Victoria ; VALERIO, MARIA ADELA ; JARIWALA, AMAR R. ; Hotez, Peter ; Diemert, David ; Loukas, Alex ; Bethony, Jeffrey . Molecular mechanisms of hookworm disease: Stealth, virulence, and vaccines. Journal of Allergy and Clinical Immunology , v. 130, p. 13-21, 2012.

  • Sripa, Banchob ; Brindley, Paul J. ; Mulvenna, Jason ; Laha, Thewarach ; Smout, Michael J. ; Mairiang, Eimorn ; Bethony, Jeffrey M. ; Loukas, Alex . The tumorigenic liver fluke Opisthorchis viverrini multiple pathways to cancer. Trends in Parasitology , v. 28, p. 395-407, 2012.

  • PINOT DE MOIRA, A. ; JONES, F. M. ; WILSON, S. ; TUKAHEBWA, E. ; FITZSIMMONS, C. M. ; MWATHA, J. K. ; Bethony, J. M. ; KABATEREINE, N. B. ; DUNNE, D. W. . Effects of Treatment on IgE Responses against Parasite Allergen-Like Proteins and Immunity to Reinfection in Childhood Schistosome and Hookworm Coinfections. Infection and Immunity (Print) , v. 81, p. 23-32, 2012.

  • Periago, Maria V. ; Bethony, Jeffrey M. . Hookworm virulence factors: making the most of the host. Microbes and Infection , v. 14, p. 1451-1464, 2012.

  • Lobato, Lucas ; MIRANDA, ALINE ; FARIA, ISABELA MARINHO ; BETHONY, Jeffrey Michael ; Gazzinelli, Maria Flávia . Development of cognitive abilities of children infected with helminths through health education. Revista da Sociedade Brasileira de Medicina Tropical (Impresso) , v. na, p. na, 2012.

  • Smout, Michael J. ; Sripa, Banchob ; Laha, Thewarach ; Mulvenna, Jason ; Gasser, Robin B. ; Young, Neil D. ; Bethony, Jeffrey M. ; Brindley, Paul J. ; Loukas, Alex . Infection with the carcinogenic human liver fluke, Opisthorchis viverrini. Molecular Biosystems (Print) , p. xx, 2011.

  • Bethony, Jeffrey M. ; Cole, Rhea N. ; Guo, Xiaoti ; Kamhawi, Shaden ; Lightowlers, Marshall W. ; Loukas, Alex ; Petri, William ; Reed, Steven ; Valenzuela, Jesus G. ; Hotez, Peter J. . Vaccines to combat the neglected tropical diseases. Immunological Reviews , v. 239, p. 237-270, 2011.

  • Alexander, Neal ; Cundill, Bonnie ; Sabatelli, Lorenzo ; Bethony, Jeffrey M. ; Diemert, David ; Hotez, Peter ; Smith, Peter G. ; Rodrigues, Laura C. ; Brooker, Simon . Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths. Vaccine (Guildford) , v. 29, p. 3686-3694, 2011.

  • Aaron R. Jex ; Yvonne A.L. Lim ; BETHONY, J ; Peter J. Hotez ; Young, Neil D. ; Gasser, Robin B. . Soil-Transmitted Helminths of Humans in Southeast Asia Towards Integrated Control. Advances in Parasitology , v. 74, p. 231-265, 2011.

  • Geiger, Stefan Michael ; Fujiwara, Ricardo Toshio ; Freitas, Paula Albuquerque ; Massara, Cristiano Lara ; Carvalho, Omar dos Santos ; Corrêa-Oliveira, Rodrigo ; BETHONY, Jeffrey Michael . Excretory-Secretory Products from Hookworm L3 and Adult Worms Suppress Proinflammatory Cytokines in Infected Individuals. Journal of Parasitology Research (Print) , v. 2011, p. 1-8, 2011.

  • Nair, Sujit S. ; Bommana, Anitha ; Pakala, Suresh B ; Ohshiro, Kazufumi ; Lyon, Amanda J. ; Suttiprapa, Sutas ; Periago, Maria V ; Laha, Thewarach ; Hotez, Peter J. ; Bethony, Jeffrey M ; Sripa, Banchob ; Brindley, Paul J ; Kumar, Rakesh . Inflammatory response to liver fluke Opisthorchis viverrini depends on host master coregulator, MTA1, a marker for parasite induced cholangiocarcinoma. Hepatology (Baltimore, Md.) , v. x, p. n/a-n/a, 2011.

  • Loukas, Alex ; Gaze, Soraya ; Mulvenna, Jason P. ; Gasser, Robin B. ; Brindley, Paul J. ; Doolan, Denise L. ; Bethony, Jeffrey M. ; Jones, Malcolm K. ; Gobert, Geoffrey N. ; Driguez, Patrick ; McManus, Donald P. ; Hotez, Peter J. . Vaccinomics for the Major Blood Feeding Helminths of Humans. Journal of Integrative Biology / Omics (Larchmont) , v. x, p. 110616151106032, 2011.

  • Nair, Sujit S. ; Bommana, Anitha ; Bethony, Jeffrey M. ; Lyon, Amanda J. ; Ohshiro, Kazufumi ; Pakala, Suresh B. ; Rinaldi, Gabriel ; Keegan, Brian ; Suttiprapa, Sutas ; Periago, Maria V. ; Hotez, Peter J. ; Brindley, Paul J. ; Kumar, Rakesh . The metastasis-associated protein-1 gene encodes a host permissive factor for schistosomiasis, a leading global cause of inflammation and cancer. Hepatology (Baltimore, Md.) , v. 54, p. 285-295, 2011.

  • Vercruysse, Jozef ; Behnke, Jerzy M. ; Albonico, Marco ; Ame, Shaali Makame ; Angebault, Cécile ; Bethony, Jeffrey M. ; Engels, Dirk ; Guillard, Bertrand ; Hoa, Nguyen Thi Viet ; Kang, Gagandeep ; Kattula, Deepthi ; Kotze, Andrew C. ; McCarthy, James S. ; Mekonnen, Zeleke ; Montresor, Antonio ; Periago, Maria Victoria ; Sumo, Laurentine ; Tchuem Tchuenté, Louis-Albert ; Thach, Dang Thi Cam ; Zeynudin, Ahmed ; Levecke, Bruno . Assessment of the Anthelmintic Efficacy of Albendazole in School Children in Seven Countries Where Soil-Transmitted Helminths Are Endemic. Plos Neglected Tropical Diseases , v. 5, p. e948, 2011.

  • Cundill, Bonnie ; Alexander, Neal ; BETHONY, JEFF M. ; Diemert, David ; Pullan, Rachel L. ; Brooker, Simon . Rates and intensity of re-infection with human helminths after treatment and the influence of individual, household, and environmental factors in a Brazilian community. Parasitology (Cambridge. Online) , v. 138, p. 1406-1416, 2011.

  • Geiger, Stefan Michael ; ALEXANDER, NEAL DOUGLAS EDWARD ; Fujiwara, Ricardo Toshio ; Brooker, Simon ; Cundill, Bonnie ; Diemert, David Joseph ; Correa-Oliveira, Rodrigo ; BETHONY, Jeffrey Michael . Necator americanus and Helminth Co-Infections: Further Down-Modulation of Hookworm-Specific Type 1 Immune Responses. PLoS Neglected Tropical Diseases (Online) , v. 5, p. e1280, 2011.

  • SCHNEIDER, BRENT ; JARIWALA, AMAR R. ; Periago, Maria Victoria ; Gazzinelli, Maria Flávia ; BOSE, SWAROOP N. ; Hotez, Peter J. ; Diemert, David J. ; Bethony, Jeffrey M. . A history of hookworm vaccine development. Human Vaccines , v. 7, p. 1234-1244, 2011.

  • Mairiang, Eimorn ; Laha, Thewarach ; Sripa, Banchob ; Brindley, Paul J. ; Kaewkes, Sasithorn ; Bethony, Jeffrey M. ; Loukas, Alex ; Thinkhamrop, Bandit ; Tesana, Smarn ; Sithithaworn, Paiboon . Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand. Parasitology International (Print) , v. x, p. x, 2011.

  • Zhan, B. ; Perally, S. ; Brophy, P. M. ; Xue, J. ; Goud, G. ; Liu, S. ; Deumic, V. ; de Oliveira, L. M. ; BETHONY, Jeffrey Michael ; Bottazzi, M. E. ; Jiang, D. ; Gillespie, P. ; Xiao, S.-h. ; Gupta, R. ; Loukas, A. ; Ranjit, N. ; Lustigman, S. ; Oksov, Y. ; Hotez, P. . Molecular Cloning, Biochemical Characterization, and Partial Protective Immunity of the Heme-Binding Glutathione S-Transferases from the Human Hookworm Necator americanus. Infection and Immunity (Print) , v. 78, p. 1552-1563, 2010.

  • Gazzinelli, Maria Flavia ; Lobato, Lucas ; Matoso, Leonardo ; Avila, Renato ; de Cassia Marques, Rita ; Shah Brown, Ami ; Correa-Oliveira, Rodrigo ; Bethony, Jeffrey M. ; Diemert, David J. . Health Education through Analogies: Preparation of a Community for Clinical Trials of a Vaccine against Hookworm in an Endemic Area of Brazil. Plos Neglected Tropical Diseases , v. 4, p. e749, 2010.

  • Sripa, Banchob ; Bethony, Jeffrey M. ; Sithithaworn, Paiboon ; Kaewkes, Sasithorn ; Mairiang, Eimorn ; Loukas, Alex ; Mulvenna, Jason ; Laha, Thewarach ; Hotez, Peter J. ; Brindley, Paul J. . Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Tropica , p. 01-11, 2010.

  • Hotez, Peter J. ; Bethony, Jeffrey M. ; Diemert, David J. ; Pearson, Mark ; Loukas, Alex . Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nature Review, Microbiology (Print) , v. 8, p. 814-826, 2010.

  • Jariwala, Amar R ; Oliveira, Luciana M ; Diemert, David J ; Keegan, Brian ; Plieskatt, Jordan L ; Periago, Maria V ; Bottazzi, Maria E ; Hotez, Peter J ; Bethony, Jeffrey M . Potency testing for the experimental -GST-1 hookworm vaccine. Expert Review of Vaccines , v. 9, p. 1219-1230, 2010.

  • QUINNELL, R ; Pullan, Rachel L. ; Breitling LP ; GEIGER, S ; Cundill, Bonnie ; Correa-Oliveira, R. ; Brooker, Simon ; BETHONY, Jeffrey Michael . Genetic and Household Determinants of Predisposition to Human Hookworm Infection in a Brazilian Community. The Journal of Infectious Diseases , v. 202, p. 954-961, 2010.

  • Pearson, Mark ; Pickering, D. A. ; Tribolet, Leon ; Cooper, Leanne ; Mulvenna, Jason ; Oliveira,Luciana ; Bethony, Jeffrey ; HOTEZ, P ; Loukas, Alex ; Bethony, Jeffrey M. . Neutralizing Antibodies to the Hookworm Hemoglobinase ?APR?1: Implications for a Multivalent Vaccine against Hookworm Infection and Schistosomiasis. The Journal of Infectious Diseases , v. 201, p. 1561-1569, 2010.

  • Pullan, Rachel L. ; Bethony, Jeffrey M. ; Geiger, Stefan M. ; Correa-Oliveira, Rodrigo ; Brooker, Simon ; Quinnell, Rupert J. . Human helminth co-infection: No evidence of common genetic control of hookworm and Schistosoma mansoni infection intensity in a Brazilian community. International Journal for Parasitology , v. 40, p. 299-306, 2010.

  • Pearson, M. S. ; Bethony, J. M. ; Pickering, D. A. ; de Oliveira, L. M. ; Jariwala, A. ; Santiago, H. ; Miles, A. P. ; Zhan, B. ; Jiang, D. ; Ranjit, N. ; Mulvenna, J. ; Tribolet, L. ; Plieskatt, J. ; Smith, T. ; Bottazzi, M. E. ; Jones, K. ; Keegan, B. ; Hotez, P. J. ; Loukas, A. ; BETHONY, Jeffrey Michael . An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. The FASEB Journal , v. 23, p. 3007-3019, 2009.

  • Fujiwara, Ricardo T. ; Cançado, Guilherme G. L. ; Freitas, Paula A. ; Santiago, Helton C. ; Massara, Cristiano Lara ; Carvalho, Omar dos Santos ; Corrêa-Oliveira, Rodrigo ; Geiger, Stefan M. ; Bethony, Jeffrey ; BETHONY, Jeffrey Michael . Necator americanus Infection: A Possible Cause of Altered Dendritic Cell Differentiation and Eosinophil Profile in Chronically Infected Individuals. Plos Neglected Tropical Diseases , v. 3, p. e399, 2009.

  • Sripa, Banchob ; Mairiang, Eimorn ; Thinkhamrop, Bandit ; Laha, Thewarach ; Kaewkes, Sasithorn ; Sithithaworn, Paiboon ; Tessana, Smarn ; Loukas, Alex ; Brindley, Paul J. ; Bethony, Jeffrey M. . Advanced periductal fibrosis from infection with the carcinogenic human liver fluke correlates with elevated levels of interleukin-6. Hepatology (Baltimore, Md.) , v. 50, p. 1273-1281, 2009.

  • Cançado, Guilherme G. L. ; Fujiwara, R. T. ; Freitas, P. A. ; Correa-Oliveira, R. ; Bethony, J. M. . Acute generalized exanthematous pustulosis induced by itraconazole: an immunological approach. Clinical and Experimental Dermatology (Print) , v. 34, p. e709-e711, 2009.

  • Giunchetti, Rodolfo Cordeiro ; Reis, Alexandre Barbosa ; da Silveira-Lemos, Denise ; Martins-Filho, Olindo Assis ; Corrêa-Oliveira, Rodrigo ; Bethony, Jeffrey ; Vale, André Macedo ; da Silva Quetz, Josiane ; Bueno, Lilian Lacerda ; França-Silva, João Carlos . Antigenicity of a whole parasite vaccine as promising candidate against canine leishmaniasis. Research in Veterinary Science , v. 85, p. 106-112, 2008.

  • Diemert, David J. ; Bethony, Jeffrey M. ; Hotez, Peter J. . Vaccines: Hookworm Vaccines. Clinical Infectious Diseases , v. 46, p. 282-288, 2008.

  • Don, Tegan A. ; Bethony, Jeffrey M. ; Loukas, Alex . Saposin-like proteins are expressed in the gastrodermis of Schistosoma mansoni and are immunogenic in natural infections. International Journal of Infectious Diseases , v. 12, p. e39-e47, 2008.

  • Hotez, Peter ; Brindley, Paul J. ; BETHONY, Jeffrey Michael ; Charles, H.King ; Edward, J Pearce ; Jacobson, J . Helminth Infections: the great neglected tropical diseases. The Journal of Clinical Investigation , v. 118, p. 1311-1321, 2008.

  • Loukas, Alex ; Bethony, Jeffrey M . New drugs for an ancient parasite. Nature Medicine (Print) , v. 14, p. 365-367, 2008.

  • BETHONY, Jeffrey Michael ; LOUKAS, A . The Schistosomiasis Research Agenda: What now?. PLoS Medicine , v. 2, p. 1-2, 2008.

  • BETHONY, J ; DIEMERT, D ; OLIVEIRA, S ; LOUKAS, A . Can schistosomiasis really be consigned to history without a vaccine?. Vaccine (Guildford) , v. 26, p. 3373-3376, 2008.

  • BETHONY, J ; SIMON, G ; DIEMERT, D ; PARENTI, D ; DESROSIERS, A ; SCHUCK, S ; FUJIWARA, R ; SANTIAGO, H ; HOTEZ, P . Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 Hookworm Vaccine in unexposed adults. Vaccine (Guildford) , v. 26, p. 2408-2417, 2008.

  • Teixeira-Carvalho, A. ; Fujiwara, R. T. ; Stemmy, E. J. ; Olive, D. ; Damsker, J. M. ; Loukas, A. ; Correa-Oliveira, R. ; Constant, S. L. ; Bethony, J. M. . Binding of Excreted and/or Secreted Products of Adult Hookworms to Human NK Cells in Necator americanus-Infected Individuals from Brazil. Infection and Immunity (Print) , v. 76, p. 5810-5816, 2008.

  • GEIGER, S ; FUJIWARA, R ; SANTIAGO, H ; CORREAOLIVEIRA, R ; BETHONY, J . Early stage-specific immune responses in primary experimental human hookworm infection. Microbes and Infection , v. 10, p. 1524-1535, 2008.

  • Pullan, Rachel L. ; Bethony, Jeffrey M. ; Geiger, Stefan M. ; Cundill, Bonnie ; Correa-Oliveira, Rodrigo ; Quinnell, Rupert J. ; Brooker, Simon . Human Helminth Co-Infection: Analysis of Spatial Patterns and Risk Factors in a Brazilian Community. Plos Neglected Tropical Diseases , v. 2, p. e352, 2008.

  • RL, P ; BETHONY, Jeffrey Michael ; SM, G. ; B, C ; OLIVEIRA R, C. -. ; RJ, Q . Analysis of spatial patterns and risk factors in a Brazilian community. PLoS Neglected Tropical Diseases , v. 12, p. 352, 2008.

  • Jardim-Botelho, Anne ; Raff, Sophia ; de Ávila Rodrigues, Renato ; Hoffman, Heather J. ; Diemert, David Joseph ; Corrêa-Oliveira, Rodrigo ; BETHONY, Jeffrey Michael ; Gazzinelli, Maria Flávia . Hookworm, infection and polyparasitism associated with poor cognitive performance in Brazilian schoolchildren. TM & IH. Tropical medicine and international health (Print) , v. 13, p. 994-1004, 2008.

  • Hotez, Peter J ; Bethony, Jeffrey M ; Oliveira, Sergio Costa ; Brindley, Paul J ; Loukas, Alex . Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Review of Vaccines , v. 7, p. 745-752, 2008.

  • Jardim-Botelho, Anne ; Brooker, Simon ; Geiger, Stefan Michael ; Fleming, Fiona ; Souza Lopes, Aline Cristine ; Diemert, David Joseph ; Corrêa-Oliveira, Rodrigo ; BETHONY, Jeffrey Michael . Age patterns in undernutrition and helminth infection in a rural area of Brazil: associations with ascariasis and hookworm. TM & IH. Tropical medicine and international health (Print) , v. 13, p. 458-467, 2008.

  • BETHONY, J ; QUINNELL, R . Genetic epidemiology of human schistosomiasis in Brazil. Acta Tropica , v. 108, p. 166-174, 2008.

  • BETHONY, Jeffrey Michael . Protection against hookworm infection elicited by vaccination with recombinant Ac-16 is mediated by reduction of worm fecundity and canine host blood loss.. Clinical and Vaccine Immunology (Online) , v. 14, p. 281-287, 2007.

  • Diemert, David J. ; Bethony, Jeffrey M. . Debate: Letter to the Editors. TM & IH. Tropical medicine and international health (Print) , v. 12, p. 470-471, 2007.

  • BROOKER, S ; JARDIMBOTELHO, A ; QUINNELL, R ; GEIGER, S ; CALDAS, I ; FLEMING, F ; HOTEZ, P ; CORREAOLIVEIRA, R ; RODRIGUES, L ; BETHONY, J . Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene , v. 101, p. 146-154, 2007.

  • Sripa, Banchob ; Kaewkes, Sasithorn ; Sithithaworn, Paiboon ; Mairiang, Eimorn ; Laha, Thewarach ; Smout, Michael ; Pairojkul, Chawalit ; Bhudhisawasdi, Vajaraphongsa ; Tesana, Smarn ; Thinkamrop, Bandit ; Bethony, Jeffrey M. ; Loukas, Alex ; Brindley, Paul J. . Liver Fluke Induces Cholangiocarcinoma. PLoS Medicine , v. 4, p. e201, 2007.

  • GEIGER, S. M. ; CALDAS, I. R. ; MC GLONE, B. E. ; CAMPI-AZEVEDO, A. C. ; de Oliveira, L. M. ; Brooker, S. ; DIEMERT, D. ; CORRÊA-OLIVEIRA, R. ; Bethony, J. M. . Stage-specific immune responses in human Necator americanus infection. Parasite Immunology (Print) , v. 29, p. 347-358, 2007.

  • Fujiwara, R. T. ; Zhan, B. ; Mendez, S. ; Loukas, A. ; Bueno, L. L. ; Wang, Y. ; Plieskatt, J. ; Oksov, Y. ; Lustigman, S. ; Bottazzi, M. E. ; Hotez, P. ; Bethony, J. M. . Reduction of Worm Fecundity and Canine Host Blood Loss Mediates Protection against Hookworm Infection Elicited by Vaccination with Recombinant Ac-16. Clinical and Vaccine Immunology , v. 14, p. 281-287, 2007.

  • Alexander, Neal ; Bethony, Jeff ; Corrêa-Oliveira, Rodrigo ; Rodrigues, Laura C. ; Hotez, Peter ; Brooker, Simon . Repeatability of paired counts. Statistics in Medicine (Print) , v. 26, p. 3566-3577, 2007.

  • Fujiwara, R. T. ; GEIGER, S. M. ; Bethony, J. ; Mendez, S. . Comparative immunology of human and animal models of hookworm infection. Parasite Immunology (Print) , v. 28, n.1, p. 285-293, 2006.

  • Fujiwara, Ricardo T. ; Loukas, Alex ; Mendez, Susana ; Williamson, Angela L. ; Bueno, Lilian L. ; Wang, Yan ; Samuel, Andre ; Zhan, Bin ; Bottazzi, Maria Elena ; Hotez, Peter J. ; BETHONY, Jeffrey Michael . Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs. Vaccine (Guildford) , v. 24, p. 501-509, 2006.

  • Fleming, Fiona M. ; Brooker, Simon ; Geiger, Stefan M. ; Caldas, Iramaya R. ; Correa-Oliveira, Rodrigo ; Hotez, Peter J ; Bethony, Jeffrey M. . Synergistic associations between hookworm and other helminth species in a rural community in Brazil. TM & IH. Tropical medicine and international health (Print) , v. 11, n.1, p. 56-64, 2006.

  • Bethony, Jeffrey ; Brooker, Simon ; Albonico, Marco ; Geiger, Stefan M ; Loukas, Alex ; Diemert, David ; Hotez, Peter J . Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet (British edition) , v. 367, n.9521, p. 1521-1532, 2006.

  • HOTEZ, P ; BETHONY, J ; BOTTAZZI, M ; BROOKER, S ; DIEMERT, D ; LOUKAS, A . New technologies for the control of human hookworm infection. Trends in Parasitology , v. 22, p. 327-331, 2006.

  • Gazzinelli, Andrea ; BETHONY, Jeffrey Michael . The spatial distribution of Schistosoma mansoni infection before and after chemotherapy in the Jequitinhonha Valley in Brazil.. Memórias do Instituto Oswaldo Cruz (Impresso) , v. 1001, p. 63-71, 2006.

  • Tran, Mai H ; Pearson, Mark S ; Bethony, Jeffrey M ; Smyth, Danielle J ; Jones, Malcolm K ; Duke, Mary ; Don, Tegan A ; McManus, Donald P ; Correa-Oliveira, Rodrigo ; Loukas, Alex . Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis. Nature Medicine (Print) , v. 12, p. 835-840, 2006.

  • BROOKER, S ; ALEXANDER, N ; GEIGER, S ; MOYEED, R ; STANDER, J ; FLEMING, F ; HOTEZ, P ; CORREAOLIVEIRA, R ; BETHONY, J . Contrasting patterns in the small-scale heterogeneity of human helminth infections in urban and rural environments in Brazil. International Journal for Parasitology , v. 36, p. 1143-1151, 2006.

  • LOUKAS, A ; BETHONY, J ; BROOKER, S ; HOTEZ, P . Hookworm vaccines: past, present, and future. Lancet. Infectious Diseases (Print) , v. 6, p. 733-741, 2006.

  • Bethony, J. M. ; Loukas, A. ; Hotez, P. J. ; KNOX, D. P. . Vaccines against blood-feeding nematodes of humans and livestock. Parasitology (London. Print) , v. 133, p. S63, 2006.

  • Mwangi, T. W. ; Bethony, J. M. ; Brooker, S. . Malaria and helminth interactions in humans: an epidemiological viewpoint. Annals of Tropical Medicine and Parasitology , v. 100, p. 551-570, 2006.

  • MENDEZ, S ; ZHAN, B ; GOUD, G ; GHOSH, K ; DOBARDZIC, A ; WU, W ; LIU, S ; DEUMIC, V ; DOBARDZIC, R ; LIU, Y ; BETHONY, Jeffrey Michael . Effect of combining the larval antigens secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by. Vaccine (Guildford) , v. 23, n.24, p. 3123-3130, 2005.

  • Goud, Gaddam Narsa ; Bottazzi, Maria Elena ; Zhan, Bin ; Mendez, Susana ; Deumic, Vehid ; Plieskatt, Jordan ; Liu, Sen ; Wang, Yan ; Bueno, Lilian ; Fujiwara, Ricardo ; Samuel, Andre ; Ahn, So Yeong ; Solanki, Maneesha ; Asojo, Oluwatoyin A. ; Wang, Jin ; Bethony, Jeffrey M. ; Loukas, Alex ; Roy, Michael ; Hotez, Peter J. . Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine (Guildford) , v. 23, p. 4754-4764, 2005.

  • Fujiwara, Ricardo Toshio ; Vale, André Macedo ; França da Silva, João Carlos ; da Costa, Roberto Teodoro ; Quetz, Josiane da Silva ; Martins Filho, Olindo Assis ; Reis, Alexandre Barbosa ; Corrêa Oliveira, Rodrigo ; Machado-Coelho, George Lins ; Bueno, Lilian Lacerda ; BETHONY, Jeffrey Michael ; Frank, Glen ; Nascimento, Evaldo ; Genaro, Odair ; Mayrink, Wilson ; Reed, Steven ; Campos-Neto, Antonio . Immunogenicity in dogs of three recombinant antigens (TSA, LeIF and LmSTI1) potential vaccine candidates for canine visceral leishmaniasis. Veterinary Research (Print) , v. 36, n.5-6, p. 827-838, 2005.

  • Zhan, B. ; Liu, S. ; Perally, S. ; Xue, J. ; Fujiwara, R. ; Brophy, P. ; Xiao, S. ; Liu, Y. ; Feng, J. ; Williamson, A. ; Wang, Y. ; Bueno, L. L. ; Mendez, S. ; Goud, G. ; Bethony, J. M. ; Hawdon, J. M. ; Loukas, A. ; Jones, K. ; Hotez, P. J. . Biochemical Characterization and Vaccine Potential of a Heme-Binding Glutathione Transferase from the Adult Hookworm Ancylostoma caninum. Infection and Immunity (Print) , v. 73, n.10, p. 6903-6911, 2005.

  • HOTEZ, P ; Arora,S.A. ; BETHONY, Jeffrey Michael ; ME, B. ; A, L. ; OLIVEIRA R, C. -. ; S, B. . Helminth infections of children: prospects for control. Adv. Exp. Med. Biol., v. 568, p. 135-144, 2005.

  • Loukas, Alex ; Bethony, Jeffrey M. ; Mendez, Susana ; Fujiwara, Ricardo T. ; Goud, Gaddam Narsa ; Ranjit, Najju ; Zhan, Bin ; Jones, Karen ; Bottazzi, Maria Elena ; Hotez, Peter J. . Vaccination with Recombinant Aspartic Hemoglobinase Reduces Parasite Load and Blood Loss after Hookworm Infection in Dogs. PLoS Medicine , v. 2, p. e295, 2005.

  • Loukas, Alex ; Constant, Stephanie L. ; Bethony, Jeffrey M. . Immunobiology of hookworm infection. FEMS Immunology and Medical Microbiology (Print) , v. 43, n.2, p. 115-124, 2005.

  • Hotez, Peter ; Bethony, Jeff ; Brooker, Simon ; Albonico, Marco . Eliminating neglected diseases in Africa. Lancet (British edition) , v. 365, p. 2089, 2005.

  • Fujiwara, Ricardo T. ; Bethony, Jeffrey ; Bueno, Lilian L. ; Wang, Yan ; Ahn, So Yeong ; Samuel, Andre ; Bottazzi, Maria Elena ; Hotez, Peter ; Mendez, Susana . Immunogenicity of the Hookworm Na-ASP-2 Vaccine Candidate: Characterization of Humoral and Cellular Responses after Vaccination in the Sprague Dawley Rat. Human Vaccines , v. 1, p. 123-129, 2005.

  • Hotez, Peter J. ; Bethony, Jeff ; Bottazzi, Maria Elena ; Brooker, Simon ; Buss, Paulo . Hookworm: The Great Infection of Mankind . PLoS Medicine , v. 2, p. e67, 2005.

  • Bethony, Jeffrey M ; Loukas, Alex ; Smout, Michael J. ; Brooker, Simon ; Mendez, Susana ; Plieskatt, Jordan ; Goud, G. ; Bottazzi, Maria E ; Zhan, Bin ; Williamson, A. ; Williamson, Angela L. ; Lustigman S ; Lustigman, S. ; Correa-Oliveira, R. ; Xiao, Shuhua ; HOTEZ, P . Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals.. The FASEB Journal , v. 12, p. 1743-1745, 2005.

  • Brooker, Simon ; Bethony, Jeffrey ; Rodrigues, Laura C. ; Alexander, Neal ; Hotez, Peter . Epidemiological, immunological and pratical considerations in developing a human hookworm vaccine. Expert Review of Vaccines , v. 4, p. 35-50, 2005.

  • Magalhaes, Telcia ; Gazzinelli, Giovani ; Alvarez, Maria Carolina B ; F.C. Lima ; Fraga, Lucia Alves Oliveira ; Silveira, Alda Maria S ; Gazzinelli, Andrea ; Bethony, Jeffrey ; LoVerde, Philip T. ; Caldas, Iramaya R. ; Correa-Oliveira, Rodrigo ; Prata, Aluizio ; Bethony, Jeffrey . Comparative clinical and ultrasound study of egg-negative and egg-positive individuals from Schistosoma mansoni low morbidity endemic areas, and hospitalized patients with hepatosplenic disease. Revista da Sociedade Brasileira de Medicina Tropical (Impresso) , v. xx, p. xx-xx, 2005.

  • GEIGER, S ; Massara, Cristiano L. ; Bethony, J. ; Soboslay, Peter T. ; Correa-Oliveira, R. . Cellular responses and cytokine production in post-treatment hookworm patients from an endemic area in Brazil. Clinical and Experimental Immunology (Print) , v. 136, p. 334-340, 2004.

  • Portela, Ricardo&nbsp ; Bethony, Jeffrey ; Costa, Maria&nbsp ; Gazzinelli, Andréa ; Vitor, Ricardo&nbsp ; Hermeto, Flavio&nbsp ; Oliveira, Correa ; Gazzinelli, Ricardo&nbsp . A Multihousehold Study Reveals a Positive Correlation between Age, Severity of Ocular Toxoplasmosis, and Levels of Glycoinositolphospholipid?Specific Immunoglobulin A. The Journal of Infectious Diseases , v. 190, n.1, p. 175-183, 2004.

  • SILVEIRA, A ; BETHONY, Jeffrey Michael . Human schistosomiasis mansoni: intensity of infection differentially affects the production of interleukin-10, interferon-? and interleukin-13 by soluble egg antigen or adult worm antigen stimulated cultures. Transactions of the Royal Society of Tropical Medicine and Hygiene , v. 98, n.10, p. 514-519, 2004.

  • E., Speziali ; J., Bethony ; O., Martins-filho ; Fraga, L. A. O. ; Lemos, D. S. ; Souza, L. J. ; R., Correa-Oliveira ; Faria, A. M. C. . Production of interferon-γ by natural killer cells and aging in chronic human schistosomiasis. Mediators of Inflammation (Print) , v. 13, p. 327-333, 2004.

  • Hsieh,GCF ; Loukas, A. ; Wahl, AM ; Bhatia,M ; Yan, Wang ; Williamson, A. ; Kehn,KW ; Maruyama,H ; BETHONY, Jeffrey Michael ; Constant, Stephanie L. . A secreted protein from the human hookworm Necator americanus binds selectively to NK cells and induces interferon-gamma production. Journal of Immunology, v. 173, n.4, p. 2699-2704, 2004.

  • BROOKER, S ; BETHONY, J ; HOTEZ, P . Human Hookworm Infection in the 21st Century. Advances in Parasitology , v. 58, p. 197-288, 2004.

  • Quinnell, R. J. ; Bethony, J. ; Pritchard, D. I. . The immunoepidemiology of human hookworm infection. Parasite Immunology (Print) , v. 26, n.8, p. 443-454, 2004.

  • Bethony, Jeffrey ; Williams, Jeff T. ; Brooker, Simon ; Gazzinelli, Andrea ; Gazzinelli, Maria F. ; LoVerde, Philip T. ; Correa-Oliveira, Rodrigo ; Kloos, Helmut . Exposure to Schistosoma mansoni infection in a rural area in Brazil. Part III: household aggregation of water-contact behaviour. TM & IH. Tropical medicine and international health (Print) , v. 9, n.3, p. 381-389, 2004.

  • Hotez, P. ; Brooker, Simon ; Bethony, J. ; Botazzi ME ; Loukas, A. ; Xiao, S. . Hookworm Infection. The New England Journal of Medicine , v. 351, p. 799-807, 2004.

  • Rocha, Gifone Aguiar ; Rocha, Andreia Maria Camargos ; Silva, Luciana Diniz ; Santos, Adriana ; Bocewicz, Ana Carolina Dias ; Queiroz, Renata de Magalhaes ; Bethony, Jeffrey ; Gazzinelli, Andrea ; Correa-Oliveira, Rodrigo ; Queiroz, Dulciene Maria Magalhaes . Transmission of Helicobacter pylori infection in families of preschool-aged children from Minas Gerais, Brazil. TM & IH. Tropical medicine and international health (Print) , v. 8, n.11, p. 987-991, 2003.

  • Hotez, Peter ; DeSilva, N ; Brooker, Simon ; BETHONY, Jeffrey Michael . Soil-transmitted helminth infections: The nature, causes and burden of the condition. Disease Control Priorities Project: working paper 3, v. xx, p. xx-xx, 2003.

  • HOTEZ, P ; Bethony, Jeffrey M. . Progress in the development of a recombinant vaccine for human hookworm disease: The Human Hookworm Vaccine Initiative. International Journal for Parasitology , v. 33, p. 1245-1258, 2003.

  • SM, G. ; CL, M. ; BETHONY, Jeffrey Michael ; PT, S. ; OS, C. ; OLIVEIRA R, C. -. . Cellular responses and cytokine profiles in Ascaris lumbricoides and Trichuris trichiura infected patients. Parasite Immunology, v. 24, p. 499-509, 2002.

  • Bethony, Jeffrey ; Chen, Jizhang ; Lin, Shaoxiong ; Xiao, Shuhua ; Zhan, Bin ; Li, Shangwen ; Xue, Haichou ; Xing, Fuying ; Humphries, Debbie ; Yan, Wang ; Chen, Grace ; Foster, Virginia ; Hawdon, John&nbsp ; Hotez, Peter&nbsp . Emerging Patterns of Hookworm Infection: Influence of Aging on the Intensity of Infection in Hainan Province, People s Republic of China. Clinical Infectious Diseases , v. 35, n.11, p. 1336-1344, 2002.

  • AMS Silveira ; Bethony, Jeff ; A. Gazzinelli ; Kloos, Helmut ; LF,Alves Oliveira ; Prata, A ; Guerra, HL ; LoVerde, Philip T. ; Oliveira, RC ; Gazzinelli, Giovani . High levels of IgG4 to Schistosoma mansoni egg antigens are observed in individuals with periportal fibrosis. American Journal of Tropical Medicine and Hygiene, v. 66, n.5, p. 542-549, 2002.

  • HOTEZ, P ; Bin, Z ; BETHONY, Jeffrey Michael ; Jin, Q ; Hawdon, J. M. ; Young HA ; Simmens, S ; Hitzelberg, Q ; Zook, BC . Natural History of primary canine hookworm infections following three different oral doses of third - stage infective larvae of Ancylostoma caninum. Comparative Parasitology, v. 69, p. 72-80, 2002.

  • Hotez, Peter ; ZHAN, B ; BETHONY, J . Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine. Journal of Veterinary Parasitology , v. 88, p. 684-690, 2002.

  • Geiger, Stefan M. ; Massara, Cristiano L. ; Bethony, Jeffrey ; Soboslay, Peter T. ; Carvalho, Omar S. ; Corrêa-Oliveira, Rodrigo . Cellular responses and cytokine profiles in infected patients. Parasite Immunology (Print) , v. 24, p. 499-509, 2002.

  • Bethony, Jeffrey ; Williams, Jeff T. ; Kloos, Helmut ; Blangero, John ; Alves-Fraga, Lucia ; Buck, Germaine ; Michalek, Arthur ; Williams-Blangero, Sarah ; LoVerde, Philip T. ; Correa-Oliveira, Rodrigo ; Gazzinelli, Andrea . Exposure to Schistosoma mansoni infection in a rural area in Brazil. II: Household risk factors. TM & IH. Tropical medicine and international health (Print) , v. 6, p. 136-145, 2001.

  • BETHONY, Jeffrey Michael ; Williams, JT ; Almasy,L ; OLIVEIRA R, C. -. ; Blangero, John ; Williams-Blangero, Sarah . Genetic analysis of quantitative traits in highly ascertained samples: total serum IgE in families with asthma. Genetic Epidemiology, v. 21, p. 174-175, 2001.

  • BETHONY, Jeffrey Michael ; Gazzinelli, Andrea ; Pereira, WR ; Lopes, A. ; Carvalho, AP ; Alves Oliveira,LF ; Blangero, John ; LoVerde, P. T. ; OLIVEIRA R, C. -. . Genetic epidemiology of a fecal egg excretion during Schistosoma mansoni infection in an endemic area in Minas Gerais. Memórias do Instituto Oswaldo Cruz, v. 96, p. 49-56, 2001.

  • BETHONY, Jeffrey Michael ; Kloos, Helmut ; A. Gazzinelli ; Silveira Soares,B ; Costa Tempe,P ; Page,K ; Grzywacz,C ; Lewis,F ; Minchella,D ; OLIVEIRA R, C. -. . The distribution of Biomphalaria spp. in different habitats in relation to physical, biological, water contact and cognitive factors in a rural area in Minas Gerais, Brazil. Memórias do Instituto Oswaldo Cruz, v. 96, p. 57-66, 2001.

  • Gazzinelli, Andrea ; Bethony, Jeffrey ; Fraga, L. Alves ; LoVerde, P. T. ; Correa-Oliveira, R. ; Kloos, Helmut . Exposure to Schistosoma mansoni infection in a rural area of Brazil. I: Water contact. TM & IH. Tropical medicine and international health (Print) , v. 6, p. 126-135, 2001.

  • Bethony, J. ; Silveira,AMS ; Alves Oliveira,LF ; Thakur, A. ; Gazzinelli, G. ; Correa-Oliveira, R. ; LoVerde, P . Familial Resemblance in Humoral Immune Response to Defined and Crude Antigens in an Endemic Area in Brazil. The Journal of Infectious Diseases , v. 180, p. 1665-1673, 1999.

  • HOTEZ, P ; GHOSH, K ; Hawdon, J. M. ; Narasinham,S ; Jones, B ; BETHONY, Jeffrey Michael . Vaccines for hookworm infection. Pediatric Infectious Diseases Journal, v. 16, n.10, p. 935-940, 1997.

  • Bethony, Jeffrey M ; Bottazzi, Maria Elena ; Shah Brown, Ami ; Diemert, David ; Hotez, P. ; Loukas, Alex . Hookworm Vaccines. 4. ed. Informa Healthcare, 2008. v. 1. 7p .

  • BETHONY, Jeffrey Michael . Parasitic Disease Vaccines.. Vaccines 5. : , 2008, v. , p. -.

  • Loukas, Alex ; BETHONY, Jeffrey Michael ; Andre Capron ; McManus, Donald P . Vaccines Aganinst Shistosomiasis. New Generation Vaccines.. 4ed.: Informa Healthcare, 2008, v. 1, p. 808-819.

  • BETHONY, Jeffrey Michael . Soil-transmitted Helminths (Geohelminths). In Manson's Tropical Diseases. : , 2008, v. , p. -.

  • Hotez, Peter ; Bundy, DAP ; Beegle, K ; Brooker, S. ; Drake, L ; de Silva N ; Montresor A ; Engels, D ; Jukes M ; Chitsulo, L ; Chow J ; laxminarayan R ; Michaud C ; BETHONY, J ; Correa-Oliveira, R. ; Shuhua X ; Fenwick A ; Savioli L . Helminth infections: Soil-transmitted Helminth Infections and Schistosomiais. Disease Control Priorities in Developing Countries.. 2ed.: The World Bank Group, 2006, v. 1, p. 467-482.

  • HOTEZ, P ; Arora,S.A. ; BETHONY, Jeffrey Michael ; Bottazzi, Maria E ; Correa-Oliveira, R. ; Loukas, Alex ; Brooker, Simon . Helminth infections of children: Prospects for control . Hot topics in infection and immunity. In: Pollard AJ, Finn A. (Org.). Advances in Experimental Medicine and Biology. xxed.: Kluwer Academic, 2005, v. 568, p. 135-142.

  • Beegle, K ; Hotez, P. ; Bundy, DAP ; K, B. ; Brooker, Simon ; DeSilva, N ; Montesor,A ; Engels, D ; Drake, L ; Chitsulo,L ; BETHONY, Jeffrey Michael . Helminth infections. In: WHO, World Bank, NIH. (Org.). Disease Control Priority Projects in Developing Countries. 2ed.: Oxford University Press, 2005, v. , p. -.

  • BETHONY, Jeffrey Michael ; Williams,JT . Host Genetics and Shistosomiasis. In: Secor WE, Colley D. (Org.). World Class Parasites:Shistosomiasis. Dordrecht: Kluwer Academic, 2004, v. , p. -.

  • HOTEZ, P ; BETHONY, Jeffrey Michael . Parasitic disease vaccines. In: Plotkin SA, Orenstein WA. (Org.). Vaccines. 4ed.Philadelphia: Saunders, 2002, v. x, p. 1291-1295.

  • HOTEZ, P ; Zhan, Bin ; Loukas, A. ; BETHONY, Jeffrey Michael ; Aschom J A ; GHOSH, K ; Hawdon, J. M. ; Brandt W ; Russell,PK . Vaccines against human hookworm disease. In: Leine MM, Kaper JB, Rappuoli R, Liu M, Good M. (Org.). New Generation Vaccines. 3ed.New York: Marcel Dekker, 2002, v. , p. -.

Prêmios

2002

Ashton Cuckler Award for Best New Researcher in Parasitology, American Society of Parasitology.

2001

Saxon Grahan Award for Excellence in Epidemiologic Research, School of Medicine and Biomedical Sciences.

2000

Best Doctoral Dissertation In Epidemiology, School of Medicine, State University of New York at Buffalo.

Histórico profissional

Endereço profissional

  • Fundação Oswaldo Cruz, Centro de Pesquisas René Rachou, Laboratório de Imunologia. , Av. Augusto de Lima 1715, Barro Preto, 30190-002 - Belo Horizonte, MG - Brasil, Telefone: (31) 33497778, URL da Homepage:

Experiência profissional

2002 - 2008

George Washington University

Vínculo: , Enquadramento Funcional: Professor Assistente, Carga horária: 40

Outras informações:
Professor Assistente do Departamento de Microbiologia, Imunologia e Medicina Tropical, School of Medicine and Health Sciences e George Washington University Medical Center, Washington,DC. Participação em Comitês de Ética.

Atividades

  • Direção e administração, George Washington University Medical Center, .,Cargo ou função, Director, Masters in Public Health Laboratory Sciences and Infectious Diseases.

  • Direção e administração, George Washington University Medical Center, .,Cargo ou função, Participação em comitê de ética.

  • Direção e administração, .,Cargo ou função, Director, Antigen Testing and Immunology Unit.

  • Pesquisa e desenvolvimento , School Of Health And Allied Health Sciences, .,Linhas de pesquisa

  • Ensino, Epidemiology, Nível: Pós-Graduação,Disciplinas ministradas, Molecular epidemiology, Immunology, Genetic Epidemiology, Epidemiology

1997 - Atual

Fundação Oswaldo Cruz

Vínculo: Pesquisador visitante, Enquadramento Funcional: Diretor do Laboratório de Imunologia Clinica