Tudor Mihai Baetu

Pós-doutorado

Idiomas

Áreas de atuação

Participação em eventos

Participação em bancas

Orientou

Produções bibliográficas

• BAETU, TUDOR M. . The Completeness of Mechanistic Explanations. Philosophy of Science (Online University of Chicago. Press) , v. 82, p. 775-786, 2015.

• 2014 BAETU, TUDOR M. . Models and the mosaic of scientific knowledge. The case of immunology. Studies in History and Philosophy of Biological and Biomedical Sciences , v. 45, p. 49-56, 2014.

• BAETU, TUDOR M. . Review of In Search of Mechanisms: Discoveries across the Life Sciences. History and Philosophy of the Life Sciences , v. 36, p. 459, 2014.

• 2013 BAETU, TUDOR M. ; BARWICH, ANN-SOPHIE ; BROOKS, DANIEL ; DUTREUIL, SÉBASTIEN ; GERMAIN, PIERRE-LUC . Model Thinking in the Life Sciences: Complexity in the Making. Biological Theory , v. 8, p. 121-124, 2013.

• 2013 BAETU, TUDOR M. . Chance, Experimental Reproducibility, and Mechanistic Regularity. International Studies in the Philosophy of Science , v. 27, p. 253-271, 2013.

• 2012 BAETU, T. M. . Genomic Programs as Mechanism Schemas: A Non-Reductionist Interpretation. The British Journal for the Philosophy of Science , v. 63, p. 649-671, 2012.

• 2012 BAETU, TUDOR M. . Defining Species: A Multi-Level Approach. Acta Biotheoretica , v. 60, p. 239-255, 2012.

• 2012 BAETU, TUDOR M. . Emergence, therefore antireductionism? A critique of emergent antireductionism. Biology & Philosophy (Print) , v. 27, p. 433-448, 2012.

• 2012 BAETU, TUDOR M. . Mechanistic Constraints on Evolutionary Outcomes*. Philosophy of Science (Online University of Chicago. Press) , v. 79, p. 276-294, 2012.

• 2012 BAETU, TUDOR M. . Genes after the human genome project. Studies in History and Philosophy of Biological and Biomedical Sciences , v. 43, p. 191-201, 2012.

• 2012 BAETU, T. . Review of 'Transformations of Lamarckism: From Subtle Fluids to Molecular Biology'. History and Philosophy of the Life Sciences , v. 34, p. 481, 2012.

• 2012 BAETU, TUDOR M. . Filling in the mechanistic details: two-variable experiments as tests for constitutive relevance. European Journal for Philosophy of Science , v. 2, p. 337-353, 2012.

• 2011 BAETU, TUDOR M. . A Defense of Syntax-Based Gene Concepts in Postgenomics: Genes as Modular Subroutines in the Master Genomic Program. Philosophy of Science (Online University of Chicago. Press) , v. 78, p. 712-723, 2011.

• 2010 BAETU, TUDOR . The Referential Convergence of Gene Concepts Based on Classical and Molecular Analyses. International Studies in the Philosophy of Science , v. 24, p. 411-427, 2010.

• 2002 BAETU, TUDOR M . On the TRAIL to apoptosis. Cytokine & Growth Factor Reviews , v. 13, p. 199-207, 2002.

• 2001 BAETU, T. M. . Disruption of NF- B Signaling Reveals a Novel Role for NF- B in the Regulation of TNF-Related Apoptosis-Inducing Ligand Expression. The Journal of Immunology (1950) , v. 167, p. 3164-3173, 2001.

• BAETU, TUDOR M. . From Mechanisms to Mathematical Models and Back to Mechanisms: Quantitative Mechanistic Explanations. Explanation in Biology. 1ed.Dordrecht: Springer, 2015, v. , p. 1-.

• BAETU, TUDOR M. . When is a Mechanistic Explanation Satisfactory? Reductionism and Antireductionism in the Context of Mechanistic Explanations. In: Gabriel Sandu; Ilie Parvu; Iulian Toader. (Org.). Romanian Studies in the History and Philosophy of Science. 1ed.Dordrecht: Springer, 2015, v. 313, p. 1-.

• BAETU, T. M. . Mechanism Schemas and the Relationship between Biological Theories. In: P. McKay; J. Williamson; F. Russo. (Org.). Causality in the Sciences, Oxford: Oxford University Press, pp. 407-424. 1ed.Oxford: Oxford University Press, 2011, v. , p. 407-424.

• BAETU, TUDOR M. . From interventions to mechanistic explanations. Synthese (Dordrecht) , 2015.

• BAETU, T. M. . The 'Big Picture': The Problem of Extrapolation in Basic Research. British Journal for the Philosophy of Science , 2015.

• BAETU, TUDOR M. . When Is a Mechanistic Explanation Complete?. 2013. (Apresentação de Trabalho/Conferência ou palestra).

• BAETU, TUDOR M. . The Norms of Mechanistic Explanation. 2013. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Models as Local Frameworks for Integrating Knowledge about Phenomena. 2013. (Apresentação de Trabalho/Conferência ou palestra).

• BAETU, TUDOR M. . Explanatory Pluralism in Systems Biology. 2013. (Apresentação de Trabalho/Conferência ou palestra).

• BAETU, TUDOR M. . Quantitative Mechanistic Explanations. 2012. (Apresentação de Trabalho/Simpósio).

• BAETU, TUDOR M. . A Multi-Level Approach to Defining Species. 2012. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Elucidating the Quantitative-Dynamic Aspects of Molecular Mechanisms. 2012. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . The Integration of Mathematical Modeling in Molecular Biology. 2012. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Mechanistic Constraints on Evolutionary Outcomes. 2011. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . How Contingent Is Evolution?. 2011. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Contemporary Concepts of the Gene. 2011. (Apresentação de Trabalho/Simpósio).

• BAETU, TUDOR M. . Filling In the Mechanistic Details: Two-Variable Experiments as Tests for Constitutive Relevance. 2011. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . The referential convergence of gene concepts based on classical and molecular analyses?. 2010. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . A defense of syntax-based gene concepts in postgenomics: Genes as modular subroutines in the master genomic program?. 2010. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Genomic Programs as Mechanisms Schemas. 2010. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Gene Concepts. 2010. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Co-Referential Models and the Cumulativity of Scientific Knowledge. 2007. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Le traitement déductif des idéalisations. 2006. (Apresentação de Trabalho/Congresso).

• BAETU, TUDOR M. . Confirmation Strategies in Experimental Biology. 2006. (Apresentação de Trabalho/Conferência ou palestra).

• BAETU, TUDOR M. . Models and Theories in Molecular Biology. 2005. (Apresentação de Trabalho/Conferência ou palestra).

• BAETU, TUDOR M. . The Up-Regulation of TRAIL Expression in Activated T-cells is Mediated via NF-κB Signalling?, Third Joint Meeting of the ICS/ISICR, Amsterdam. 2000. (Apresentação de Trabalho/Congresso).

Outras produções

Projetos de pesquisa

• 2012 - 2014

  Causation and mechanisms, Descrição: Mechanistic accounts provide novel solutions to fundamental dilemmas in philosophy of science. For example, many authors agree that there are no such things as universal/necessary laws in biology. However, if the notion of law is completely abandoned, then anything will turn out to be possible in evolution, and this does not seem to be the case. I argue that generalizations in biology can be accounted for as ?mechanistic constraints? generating probabilistic biases towards preferred outcomes [?Mechanistic Constraints on Evolutionary Outcomes? (2012d)]. Thus, mechanistic constraints bridge the gap between the more fundamental law-like generalizations in the physical sciences and contingent generalizations in the life sciences. I am interested in finding out how chance correlations are distinguished from potential phenomena produced by mechanisms [?Chance, Experimental Reproducibility, and Mechanistic Regularity? (2013)]; how mechanisms are inferred from bits and pieces of knowledge of causally-relevant factors [?Filling In the Mechanistic Details: Two-Variable Experiments as Tests for Constitutive Relevance? (2012b)]; and how mechanisms are different from modular assemblages of causal factors [?How Mechanisms Relate to Causes: Disentangling the Relationship between Causal Dependence and Productive Mechanisms? (in preparation-c)]. Finally, I intend to investigate the possibility of devising techniques and treatments in the absence of a thorough theoretical understanding of how a technique/treatment works (?theory-free experimental investigation?), and the role knowledge of mechanisms plays in deciding whether a treatment is beneficial; these issues are highly pertinent to current debates in bioethics, public policy, and the new standards established by evidence-based medicine.. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Tudor Mihai Baetu - Coordenador.

• 2008 - 2010

  Genes and genomes, Descrição: An important part of my research targeted the evolution of the concept of the gene from classical genetics, to molecular biology, to present-day genomics. I show how partial co-reference of concepts associated with different fields of investigation plays a crucial role in bridging the transfer of knowledge from one field to another, thus promoting their integration [?The Referential Convergence of Gene Concepts Based on Classical and Molecular Analyses? (2010)]. I discuss and analyze novel, bioinformatics (?syntax-based?) concepts of the gene [?A Defense of Syntax-Based Gene Concepts in Postgenomics: ?Genes as Modular Subroutines in the Master Genomic Program?? (2011a)]. I show how concepts of the gene are revised in light of new discoveries, and I argue that contemporary experimental practice relies on a dynamic interplay between two distinct families of gene concepts, thus resisting attempts to collapse different concepts into a unified, over-arching concept [?Genes After the Human Genome Project? (2011c)]. Finally, I argue that ?genomic programs? are in fact abstract representations of mechanisms highlight ing the genomic determinants of inheritance and their organizational features at work in the wider context of the mechanisms of genome expression [?Genomic Programs as Mechanism Schemas: A Non-Reductionist Interpretation? (2012c)]. Most notably, these abstract representations play an important role in mediating the transfer of information between experimental branches of biology, such as molecular and developmental biology, and more fields of investigation adopting more theoretical approaches, such as bioinformatics and systems biology.. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Tudor Mihai Baetu - Coordenador.

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