Angela María Alvarez Gómez

Pharmaceutical Chemist with Master degree and PhD in Biomedical Sciences (emphasis on Biochemistry, Pharmacology and Physiology) from the University of Antioquia (Medellín, Colombia). I developed my thesis at the Reproduction Group (Medicine School), and I evaluated the cellular function and signaling pathways modulation for drugs currently used to treat an autoimmune disease, using several cells lines from placental and endhotelial source. During my PhD I received additional scientific trainning in international laboratoratories. At the end of my academic formation, I worked in the Ophidism-Scorpionism Program to carry out immunological and biochemical tests for snake venoms and for antibodies obtained from immunizations procedures in our laboratory. For several years I taught courses in Pharmacology Laboratory and Physiology Laboratory at the School of Pharmaceutical Sciences (University of Antioquia). Currently, I am a post-doctorate fellow at the Butantan Institute (São Paulo, Brazil), working with the screening of peptides derived from animal toxins to determine their potential as regenerative agents in muscular tissue, and lately, working in a platform for genome editing in mammalian cells. My experience is focused on basic research in the field of Biomedicine, using molecular life sciences (cell biology, molecular biology, immunology and biochemistry) techniques into research and development of new uses for common drugs, explore mechanisms of action, and look for new drugs and therapeutical targets.

Informações coletadas do Lattes em 02/05/2025

Acadêmico

Formação acadêmica

Doutorado em Ciencias Básicas Biomédicas

2011 - 2015

Universidad de Antioquia, UdeA
Título: Functionality of the human trophoblast and deleterious effects of antiphospholipid antibodies: advances on their pharmacological modulation
Orientador: Angela P. Cadavid
Coorientador: Norman Balcázar. Bolsista do(a): Administrative department of Science Technology and Research, COLCIENCIAS, Colômbia.

Mestrado em Ciencias Básicas Biomédicas

2009 - 2012

Universidad de Antioquia, UdeA
Título: Antiphospholipid antibody levels, trophoblastic proliferation in the presence of enoxaparin and aspirin, and determination of the protein profile in serum of women with gestational morbidity associated with antiphospholipid syndrome, Ano de Obtenção: 2013
Orientador: Angela P. Cadavid
Coorientador: Sergio Parra.

Graduação em Química Farmacéutica

2002 - 2007

Universidad de Antioquia, UdeA

Pós-doutorado

2018

Pós-Doutorado. , Instituto Butantan, IBU, Brasil. , Bolsista do(a): Fundação de Amparo à Pesquisa do Estado de São Paulo, FAPESP, Brasil.

Idiomas

Bandeira representando o idioma Inglês

Compreende Bem, Fala Razoavelmente, Lê Bem, Escreve Bem.

Bandeira representando o idioma Espanhol

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Bandeira representando o idioma Português

Compreende Bem, Fala Razoavelmente, Lê Bem, Escreve Razoavelmente.

Áreas de atuação

Grande área: Ciências Biológicas / Área: Farmacologia / Subárea: Farmacologia Bioquímica e Molecular.

Participação em eventos

XVI Congresso da Sociedade Brasileira de Toxinologia. Recombinant proteins for Lonomia obliqua bristlespositively modulates the myoblast proliferation process. 2022. (Congresso).

XXXIV Reunião anual FeSBE. Influence of IL-1b and TNF-a on mouse myoblast cells transition between proliferation and differentiation events. 2019. (Congresso).

Participação em bancas

Aluno: Claudia Rojo

Alvarez, AM; CADAVID, ANGELA P.; joan villena. Síndrome Antifosfolípido, manifestaciones trombóticas y su efecto en el proceso de invasión del trofoblasto. Una Revisión Narrativa de la Literatura. 2020. Dissertação (Mestrado em Ciencias Médicas) - Universidad de Valparaiso.

Aluno: Angie Carolina Morales Vivares

Alvarez, AM. Efecto del consumo de marihuana sobre los parámetros espermáticos humanos: aproximación in vivo. 2021. Trabalho de Conclusão de Curso (Graduação em Microbiología y Bioanálisis) - Universidad de Antioquia.

Aluno: Jorge Andrés Ríos

Alvarez, AM; CADAVID, A. P.. Detección del estrés oxidativo en el síndrome antifosfolípido obstétrico. 2018. Trabalho de Conclusão de Curso (Graduação em Microbiología y Bioanálisis) - Universidad de Antioquia.

Orientou

Carlos Mario Rodríguez

Daño endotelial inducido por los anticuerpos antifosfolípidos: papel del estrés oxidativo y mTOR en la regulación de procesos autofágicos; 2019; Dissertação (Mestrado em Ciencias Básicas Biomédicas) - Universidad de Antioquia, Comité para el Desarrollo de la Investigación; Coorientador: Angela María Alvarez Gómez;

Manuel Alejandro Granada

Modulación de la activación de óxido nítrico sintasa endotelial por las lipoxinas inducidas por aspirina: ¿un posible mecanismo de acción de la aspirina en el síndrome antifosfolípido?; 2018; Dissertação (Mestrado em Ciencias Básicas Biomédicas) - Universidad de Antioquia, Administrative department of Science Technology and Research; Coorientador: Angela María Alvarez Gómez;

Carolina Daga Motta

Establishment of a NALP3 inflammasome study model in myoblast cells; 2021; Iniciação Científica; (Graduando em Biomedicina) - Centro Universitário São Camilo, Conselho Nacional de Desenvolvimento Científico e Tecnológico; Orientador: Angela María Alvarez Gómez;

Ginet Melissa Gallego - Dubier Mauricio Henao

Efecto de cinco extractos de plantas colombianas sobre espermatozoides humanos; 2012; Iniciação Científica; (Graduando em Química Farmacéutica) - Universidad de Antioquia; Orientador: Angela María Alvarez Gómez;

Juliana Montoya

Los anticuerpos antifosfolípidos de mujeres con pérdida gestacional y trombosis vascular disminuyen la diferenciación de células trofoblásticas derivadas de coriocarcinoma; 2018; Orientação de outra natureza; (Biología) - Universidad de Antioquia; Orientador: Angela María Alvarez Gómez;

Sandra Milena López

Diferenciación de células trofoblasticas en presencia de anticuerpos antifosfolípidos de pacientes con morbilidad gestacional; 2015; Orientação de outra natureza; (Biología) - Universidad de Antioquia; Orientador: Angela María Alvarez Gómez;

Yonhatan Ramírez

Efecto de la Enoxaparina, la Aspirina y la 15-Epilipoxina A4 sobre la alteración de la invasión trofoblástica in vitro inducida por anticuerpos antifosfolípidos; 2015; Orientação de outra natureza; (Microbiología y Bioanálisis) - Universidad de Antioquia; Orientador: Angela María Alvarez Gómez;

Produções bibliográficas

  • Alvarez, AM ; GÓMEZ-GUTIERREZ, A. M. ; BUENO, JULIO ; RÚA-MOLINA, C. ; CADAVID, ANGELA P. . Obstetric antiphospholipid syndrome: An approach from glycans of the immunoglobulin G. Journal of Human Reproductive Sciences , v. 14, p. 97, 2021.

  • SILVA, N. C. ; ALVAREZ, ANGELA M ; DEOCESANO-PEREIRA, CARLOS ; LATORRE, CONSUELO ; MOREIRA, VANESSA . Catalytically active phospholipase A2 myotoxin from Crotalus durissus terrificus induces proliferation and differentiation of myoblasts dependent on prostaglandins produced by both COX-1 and COX-2 pathways. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES , v. 187, p. 603-613, 2021.

  • ALVAREZ-FLORES, MIRYAM PAOLA ; GOMES, RENATA NASCIMENTO ; TREVISAN-SILVA, DILZA ; OLIVEIRA, DOUGLAS SOUZA ; BATISTA, ISABEL DE FÁTIMA CORREIA ; BURI, MARCUS VINICIUS ; ALVAREZ, ANGELA MARIA ; DEOCESANO-PEREIRA, CARLOS ; DE SOUZA, MARCELO MEDINA ; CHUDZINSKI-TAVASSI, ANA MARISA . Lonomia obliqua Envenoming and Innovative Research. Toxins , v. 13, p. 832, 2021.

  • RODRÍGUEZ, CARLOS M. ; VELÁSQUEZ-BERRÍO, MANUELA ; RÚA, CAROLINA ; VIANA, MARTA ; ABRAHAMS, VIKKI M. ; CADAVID, ANGELA P. ; ALVAREZ, ANGELA M. . Antiphospholipid Antibodies From Women With Pregnancy Morbidity and Vascular Thrombosis Induce Endothelial Mitochondrial Dysfunction, mTOR Activation, and Autophagy. Frontiers in Physiology , v. 12, p. 70674, 2021.

  • RIBEIRO, ISABELA MORETI ; SOUTO, PAULA CRISTINA SOUZA ; BORBELY, ALEXANDRE U. ; TANABE, ELOIZA LOPES LIRA ; CADAVID, ANGELA ; ALVAREZ, ANGELA M. ; BUENO, JULIO ; AGUDELO, OLGA ; ROBLES, REGGIE GARCÍA ; AYALA-RAMÍREZ, PAOLA ; SACERDOTI, FLAVIA ; SZASZ, THEODORA ; DAMIANO, ALICIA E. ; IBARRA, CRISTINA ; ESCUDERO, CARLOS ; LIMA, VICTOR V. ; GIACHINI, FERNANDA R. . The limited knowledge of placental damage due to neglected infections: ongoing problems in Latin America. Systems Biology in Reproductive Medicine , v. 66, p. 151-169, 2020.

  • ALVAREZ, ANGELA M. ; CARDONA-MAYA, W. . Treatment of COVID-19: Old Friends for a New Enemy. Pharmaceutical and Biomedical Research , v. 6, p. 1-4, 2020.

  • ALVAREZ, ANGELA M. ; DEOCESANO-PEREIRA, CARLOS ; TEIXEIRA, CATARINA ; MOREIRA, VANESSA . IL-1β and TNF-α Modulation of Proliferated and Committed Myoblasts: IL-6 and COX-2-Derived Prostaglandins as Key Actors in the Mechanisms Involved. Cells , v. 9, p. 2005, 2020.

  • GIL'VILLA, AURA MARÍA ; ALVAREZ, ANGELA M. ; VELÁSQUEZ'BERRÍO, MANUELA ; ROJAS, MAURICIO ; CADAVID J, ANGELA P. . Role of aspirin¿triggered lipoxin A4, aspirin and salicylic acid in the modulation of the oxidative and inflammatory responses induced by plasma from women with preeclampsia. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY , v. 83, p. e13207, 2019.

  • VELASQUEZ, M. ; GRANADA, M. A. ; GALVIS, J. C. ; ALVAREZ, ANGELA ; CADAVID, A. P. . Estrés oxidativo en células endoteliales inducido por el suero de mujeres con diferentes manifestaciones clínicas del síndrome antifosfolípido. Biomedica , v. 39, p. 1-23, 2019.

  • ALVAREZ, ANGELA M. ; SAN MARTÍN, SEBASTIÁN ; MARKERT, UDO R. ; CADAVID, ANGELA P. . Modulation of antiphospholipid antibodies-induced trophoblast damage by different drugs used to prevent pregnancy morbidity associated with antiphospholipid syndrome. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY , v. 77, p. e12634, 2017.

  • ALVAREZ, ANGELA M. ; NEUBECK, S. ; PARRA, S. ; MARKERT, U. R. ; CADAVID, A. P. . Serum protein profile in women with pregnancy morbidity associated with Antiphospholipid Syndrome. Journal of Human Reproductive Sciences , v. 10, p. 10-17, 2017.

  • VELASQUEZ, M. ; ALVAREZ, ANGELA M. ; CADAVID, A. P. . Cuantificación sistematizada de la remodelación vascular in vitro en la morbilidad gestacional asociada al síndrome antifosfolípido. REVISTA CHILENA DE OBSTETRICIA Y GINECOLOGÍA (EN LÍNEA) , v. 81, p. 455-464, 2016.

  • ANDRADE, DANIELI ; KIM, MIMI ; BLANCO, LUZ P. ; KARUMANCHI, S. ANANTH ; KOO, GLORIA C. ; REDECHA, PATRICIA ; KIROU, KYRIAKOS ; ALVAREZ, ANGELA M. ; MULLA, MELISSA J. ; CROW, MARY K. ; ABRAHAMS, VIKKI M. ; KAPLAN, MARIANA J. ; SALMON, JANE E. . Interferon-α and Angiogenic Dysregulation in Pregnant Lupus Patients Who Develop Preeclampsia. Arthritis & Rheumatology , v. 67, p. 977-987, 2015.

  • ALVAREZ, ANGELA M. ; MULLA, MELISSA J. ; CHAMLEY, LAWRENCE W. ; CADAVID, ANGELA P. ; ABRAHAMS, VIKKI M. . Aspirin-Triggered Lipoxin Prevents Antiphospholipid Antibody Effects on Human Trophoblast Migration and Endothelial Cell Interactions. Arthritis & Rheumatology , v. 67, p. 488-497, 2015.

  • MAYA, WALTERCARDONA ; ALVAREZ, ANGELA ; CADAVID J, ANGELAP ; MARKERT, UDOR . Differential protein expression in seminal plasma from fertile and infertile males. Journal of Human Reproductive Sciences , v. 7, p. 206-2011, 2014.

  • Ospina-Medina, L ; Lalinde-Acevedo Paula ; ALVAREZ, ANGELA M. ; CANON, D. ; MAYORGA-TORRES, B. J. M. ; SUAREZ-PUERTA, J. ; CARDONA-MAYA, W. . Infertilidad masculina y su relación con algunas condiciones médicas. Medicina y Laboratorio , v. 20, p. 57-71, 2014.

  • Ospina-Medina, L ; ALVAREZ G, Angela M ; VALENCIA-ARANGO, V. ; CADAVID, ANGELA P. ; CARDONA-MAYA, W. . Actividad espermicida y citotóxica del extracto de Sapindus saponaria L. (jaboncillo). REVISTA CUBANA DE PLANTAS MEDICINALES , v. 18, p. 420-430, 2013.

  • Ospina-Medina, L ; ALVAREZ G, Angela M ; CORTÉS-MANCERA, F ; CADAVID J, ANGELA P. ; CARDONA-MAYA, W. . Efecto del extracto espermicida de Ananas comosus y Sapindus saponaria sobre la viabilidad, la citotoxicidad y la apoptosis celular. REVISTA CUBANA DE PLANTAS MEDICINALES , v. 18, p. 534-542, 2013.

  • SUAREZ-PUERTA, J. ; CARDONA-DUQUE, D ; ALVAREZ G, Angela M ; VALENCIA-ARANGO, V. ; CADAVID J, ANGELA P. ; CARDONA-MAYA, W. . Efecto del extracto de Anethum graveolens, Melissa officinalis y Calendula officinalis sobre espermatozoides humanos. REVISTA CUBANA DE PLANTAS MEDICINALES , v. 17, p. 420, 2012.

  • URIBE-CLAVIJO, M ; ALVAREZ G, Angela M ; VALENCIA-ARANGO, V. ; CORTÉS-MANCERA, F ; CADAVID J, ANGELA P. ; CARDONA-MAYA, W. . Espermicidas: Una alternativa de anticoncepción para considerar. TECNO LÓGICAS - IT COLOMBIANO , p. 129, 2012.

  • URIBE-CLAVIJO, M ; ALVAREZ G, Angela M ; VALENCIA-ARANGO, V. ; CORTÉS-MANCERA, F ; CADAVID J, ANGELA P. ; CARDONA-MAYA, W. . Efecto In Vitro del extracto vegetal de Ananas Comosus sobre espermatozoides humanos. TECNO LÓGICAS - IT COLOMBIANO , p. 55, 2012.

  • Ospina-Medina, L ; ALVAREZ, ANGELA ; CADAVID, ANGELA ; CARDONA-MAYA, W. . Que piensan los hombres del Valle de Aburrá acerca de la salud reproductiva. IATREIA , v. 25, p. 120-126, 2012.

  • GALLEGO, G. ; HENAO, D. M. ; Ospina-Medina, L ; ALVAREZ G, Angela M ; VALENCIA-ARANGO, V. ; CARDONA-MAYA, W. ; CADAVID J, ANGELA P. . Efecto de cinco extractos de plantas colombianas sobre espermatozoides humanos. REVISTA CUBANA DE PLANTAS MEDICINALES , v. 17, p. 84-92, 2012.

  • FITZGERALD, JUSTINE S. ; ABAD, CILIA ; ALVAREZ, ANGELA M. ; MEHTA, RATNESH BHAI ; CHAIWANGYEN, WITTAYA ; DUBINSKY, VALERIA ; SILVA, BARBARA GUEUVOGHLANIAN ; GUTIERREZ, GABRIELA ; HOFMANN, SIMONE ; HÖLTERS, SEBASTIAN ; JOUKADAR, JENNIFER ; JUNOVICH, GISELA ; KUHN, CHRISTINA ; MORALES-PRIETO, DIANA M. ; NEVERS, TANIA ; OSPINA-PRIETO, STEPHANIE ; PASTUSCHEK, JANA ; PEREIRA DE SOUSA, F. LAZARO ; SAN MARTIN, SEBASTIAN ; SUMAN, PANKAJ ; WEBER, MAJA ; MARKERT, UDO R. . Cytokines Regulating Trophoblast Invasion. ADVANCES IN NEUROIMMUNE BIOLOGY , v. 2, p. 61-97, 2011.

  • OSPINA, L. ; ÁLVAREZ-GÓMEZ, A. ; CADAVID, A. ; CARDONA-MAYA, W. . Tenofovir, agente antiviral con escasa actividad espermiostática. Actas Urologicas Espanolas , v. 35, p. 123-124, 2011.

  • ALVAREZ-GÓMEZ, ANGELA M. ; CARDONA-MAYA, WÁLTER ; FORERO, JORGE ; CADAVID, ANGELA P. . Human Spermicidal Activity of Passiflora edulis Extract. Journal of Reproduction and Contraception , v. 21, p. 95-100, 2010.

  • ÁLVAREZ-GÓMEZ, A.M.ª ; CARDONA-MAYA, W.D. ; CASTRO-ÁLVAREZ, J.F. ; JIMÉNEZ, SILVIA ; CADAVID, A. . Nuevas opciones en anticoncepción: posible uso espermicida de plantas colombianas. Actas Urologicas Espanolas , v. 31, p. 372, 2007.

  • GRANADA, M. A. ; VELASQUEZ, M. ; RÚA-MOLINA, C. ; ALVAREZ, ANGELA ; CADAVID, A. P. . Aspirin-triggered lipoxins modulate phosphorylation of endothelial nitric oxide synthase and protein nitration of endothelial cells stimulated with polyclonal IgG from patients with antiphospholipid syndrome. In: International Federation of Placental Association, 2019, Buenos Aires. Conference Abstracts in Placenta. Amsterdam: Elsevier, 2019. v. 83. p. e87.

  • RODRIGUEZ, C. M. ; VELASQUEZ, M. ; RÚA-MOLINA, C. ; ALVAREZ-GÓMEZ, ANGELA M. ; CADAVID J, ANGELAP . Aspirin-triggered lipoxins modulate phosphorylation of endothelial nitric oxide synthase and protein nitration of endothelial cells stimulated with polyclonal IgG from patients with antiphospholipid syndrome. In: International Federation of Placental Association, 2019, Buenos Aires. Conference Abstracts in Placenrta. Amsterdam: Elsevier, 2019. v. 83. p. e86.

  • ALVAREZ-GÓMEZ, ANGELA M. ; GÓMEZ-GUTIERREZ, A. M. ; BUENO, JULIO ; CADAVID, ANGELA P. . Síndrome Antifosfolipídico: una aproximación desde la Glicobiología. In: Primer Congreso Colombiano de Autoinmunidad, 2018, Bogotá. Lupus y autoinmunidad hematológica en: Revista Medicina. Bogotá: Academia Nacional de Medicina de Colombia, 2018. v. 40. p. 113.

  • VELASQUEZ, M. ; ALVAREZ, ANGELA M. ; CADAVID, ANGELA P. . Remodelación vascular como modelo in vitro para el estudio del Síndrome Antifosfolipídico Obstétrico. In: Primer Congreso Colombiano de Autoinmunidad, 2018, Bogotá. Lupus y autoinmunidad Hematológica en: Revista Medicina. Bogotá: Academia Nacional de Medicina de Colombia, 2018. v. 40. p. 110.

  • GRANADA, M. A. ; VELASQUEZ, M. ; ALVAREZ G, Angela M ; GALVIS, J. C. ; CADAVID, ANGELA P. . Evaluación de estrés nitrosativo y oxidativo en mujeres con diferentes manifestaciones clínicas del síndrome antifosfolipídico. In: Primer Congreso Colombiano de Autoinmunidad, 2018, Bogotá. Lupus y autoinmunidad hematológica en: Revista Medicina. Bogotá: Academia Nacional de Medicina de Colombia, 2018. v. 40. p. 101.

  • VELASQUEZ, M. ; ALVAREZ, ANGELA ; BUENO, JULIO ; ABRAHAMS, VIKKI M. ; CADAVID, ANGELA . Sera from patients with antiphospholipid syndrome alter the interaction between endothelial and trophoblast cells using a model of vascular remodeling. In: V Latin American Society for Maternal Fetal Interaction and Placenta, 2015, Mar del Plata. Abstracts published in Placenta. Amsterdam: Elsevier, 2015. v. 36. p. 504.

  • ALVAREZ, ANGELA ; RAMIREZ, Y. ; BALCÁZAR, NORMAN ; SAN MARTÍN, SEBASTIÁN ; MARKERT, U. R. ; CADAVID, ANGELA . Human trophoblast invasion: modulation of alterations induced by antiphospholipid antibodies. In: V Latin American Society for Maternal Fetal Interaction and Placenta, 2015, Mar del Plata. Abstracts published in Placenta. Amsterdam: Elsevier, 2015. v. 36. p. 489.

  • VELASQUEZ, M. ; ALVAREZ, ANGELA ; BUENO, JULIO ; CADAVID, ANGELA . Is the decrease of CD31 and CD34 a mechanism by which sera from patients with antiphospholipid syndrome alter vascular remodeling in placenta?. In: IMMUNOCOLOMBIA 2015, 2015, Medellín. Front. Immunol. Conference Abstract: IMMUNOCOLOMBIA2015 - 11th Congress of the Latin American Association of Immunology - 10o. Congreso de la Asociación Colombiana de Alergia, Asma e Inmunología.. Lausanne: Holtzbrink, 2015. v. 3389. p. 102.

  • Alvarez, AM ; RAMIREZ, Y. ; SAN MARTÍN, SEBASTIÁN ; MARKERT, U. R. ; CADAVID, ANGELA . Antiphospholipid antibodies effect over trophoblast cell function and pharmacological modulation. In: IMMUNOCOLOMBIA 2015, 2015, Medellín. Front. Immunol. Conference Abstract: IMMUNOCOLOMBIA2015 - 11th Congress of the Latin American Association of Immunology - 10o. Congreso de la Asociación Colombiana de Alergia, Asma e Inmunología.. Laussane: Holtzbrink, 2015. v. 3389. p. 228.

  • ANDRADE, DANIELI ; KIM, MIMI ; BLANCO, LUZ P. ; KARUMANCHI, S. ANANTH ; KOO, GLORIA C. ; REDECHA, PATRICIA ; KIROU, KYRIAKOS ; ALVAREZ, ANGELA M. ; MULLA, MELISSA J. ; CROW, MARY K. ; ABRAHAMS, VIKKI M. ; KAPLAN, MARIANA J. ; SALMON, JANE E. . Interferon-α and angiogenic dysregulation in pregnant lupus patients destined for preeclampsia. In: Lupus 2014: New Targets, New Approaches, 2014, Quebec. Special Issue in: Arthritis Research and Theraphy. London: BioMed Central, 2014. v. 16. p. A28.

  • Alvarez, AM ; CADAVID, A. P. ; CHAMLEY, LAWRENCE W. ; ABRAHAMS, VIKKI M. . Aspirin triggered lipoxin modulates human first trimester trophoblast response to antiphospholipid antibodies. In: 14th International Symposium for Immunology of Reproduction,, 2013, Boston. Special issue in American journal of Reproductive Immunology: Abstracts of the 14th International Symposium for Immunology of Reproduction. New Jersey: Wiley, 2013. v. 69. p. 98.

  • ALVAREZ, ANGELA ; RAMIREZ, Y. ; BALCÁZAR, NORMAN ; MARKERT, U. R. ; VELASQUEZ, M. ; PENA, B. ; CADAVID, ANGELA P. . Efecto sobre la función trofoblástica in vitro de los anticuerpos antifosfolípidos de pacientes con diferentes manifestaciones clínicas del sindrome antifosfolípido. In: IX Congreso Colombiano de Alergia, Asma e Inmunología, 2013, Bogotá. Special Issue in IATREIA: Trabajos de Investigación de Científicos Colombianos. Medellín: Editorial Universidad de Antioquia, 2013. v. 26. p. s38.

  • ALVAREZ, ANGELA ; CADAVID, ANGELA ; MARKERT, U. R. . Binding of antiphospholipid antibodies to trophoblastic cell lines and its effects on its physiological function. In: V Latin American Symposium on Maternal Fetal Interaction & Placenta IV Latin American Symposium on Reproductive Immunology, 2013, Foz do Iguaçú. Special Issue in Placenta: Abstracts for the V SLIMP & IV LASRI. Amsterdam: Elsevier, 2013. v. 34. p. A18.

  • ALVAREZ, ANGELA ; TORO, F. ; PARRA, S. ; MARKERT, U. R. ; CADAVID, ANGELA . Effect of aspirin and enoxaparin on serum levels of antiphospholipid antibodies and trophoblast proliferation. In: Joint International Congress: American Society for Reproductive Immunology & European Society for Reproductive Immunology, 2012, Hamburg. Special Issue in Journal of Reproductive Immunology: Abstracts of the joint International Congress of the American Society for Reproductive Immunology (ASRI) & the European Society for Reproductive Immunology (ESRI). Amsterdam: Elsevier, 2012. v. 94. p. 95.

  • CADAVID, ANGELA ; ALVAREZ, ANGELA ; CHAIWANGYEN, WITTAYA ; MARKERT, U. R. . Effect of Heparin, Aspirin and Aspirin-triggered lipoxin on STAT-3 and ERK 1/2 activation on trophoblastic cells. In: oint International Congress: American Society for Reproductive Immunology & European Society for Reproductive Immunology, 2012, Hamburg. Special Issue in Journal of Reproductive Immunology: Abstracts of the joint International Congress of the American Society for Reproductive Immunology (ASRI) & the European Society for Reproductive Immunology (ESRI). Amsterdam: Elsevier, 2012. v. 94. p. 97.

  • ALVAREZ, ANGELA ; NEUBECK, S. ; MARKERT, UDO R. ; CADAVID, A. . Differential protein expression in sera from women with recurrent pregnancy loss associated to antiphospholipid syndrome. In: First Reproductive Biology and Immunology Autum School, 2011, Magdeburg. Special Issue in Minerva Medica. Torino: Edizioni Minerva Medica, 2011. v. 102. p. 73.

  • ALVAREZ, ANGELA ; NEUBECK, S. ; CADAVID, ANGELA ; MARKERT, U. R. . Perfil proteíco de mujeres con Síndrome Antifosfolípido. In: Seminarios de Ciencias Básicas Biomédicas, 2011, Medellín. Edición especial en Actualidades Biológicas: Resúmenes del Seminario de Ciencias Básicas Biomédicas. Medellín: Editorial Universidad de Antioquia, 2011. v. 33. p. 128.

  • ALVAREZ, ANGELA ; NEUBECK, S. ; CADAVID, ANGELA ; MARKERT, U. R. . Protein profile of women with antiphospholipid syndrome. In: 8th European Congress of Reproductive Immunology, 2010, Munich. Special Issue in Journal of Reproductive Immunology: 8th European Congress of Reproductive Immunology. Amsterdam: Elsevier, 2010. v. 86. p. 80.

  • ALVAREZ, ANGELA ; SILVA, N. C. ; DEOCESANO-PEREIRA, C. ; CHUDZINSKI-TAVASSI, A. M. ; TEIXEIRA, C. ; MOREIRA, V. . Influence of IL-1b and TNFa on mouse myoblast cells transition between proliferation and differentiation events. 2019. (Apresentação de Trabalho/Congresso).

  • Alvarez, AM ; RAMIREZ, Y. ; SAN MARTÍN, SEBASTIÁN ; MARKERT, U. R. ; CADAVID, A. P. . Antiphospholipid antibodies effect over trophoblast cell function and pharmacological modulation. 2015. (Apresentação de Trabalho/Congresso).

  • Alvarez, AM ; RAMIREZ, Y. ; BALCÁZAR, NORMAN ; SAN MARTÍN, SEBASTIÁN ; MARKERT, U. R. ; CADAVID, A. P. . Human trophoblast invasion: modulation of alterations induced by antiphospholipid antibodies. 2015. (Apresentação de Trabalho/Congresso).

  • ALVAREZ, ANGELA M. ; MULLA, MELISSA J. ; CHAMLEY, LAWRENCE W. ; CADAVID, A. P. ; ABRAHAMS, VIKKI M. . Antiphopholipid antibodies disrupt trohoblast-endothelial cell interaction. 2014. (Apresentação de Trabalho/Simpósio).

  • ALVAREZ, ANGELA M. ; RAMIREZ, Y. ; BALCÁZAR, NORMAN ; VELASQUEZ, M. ; MARKERT, U. R. ; CADAVID, ANGELA P. . Efecto de los anticuerpos antifosfolípidos de pacientes con diferentes manifestaciones clínicas del síndrome. 2013. (Apresentação de Trabalho/Congresso).

  • ALVAREZ, ANGELA M. ; PARRA, S. ; TORO, F. ; CADAVID, ANGELA P. . Niveles séricos de anticuerpos antifosfolípidos y viabilidad de células trofoblásticas en presencia de aspirina y enoxaparina. 2013. (Apresentação de Trabalho/Congresso).

  • CARDONA-MAYA, W. ; CADAVID, A. ; ALVAREZ, ANGELA ; MARKERT, U. R. . Expresión diferencial de proteínas de hombres fértiles e infértiles. 2013. (Apresentação de Trabalho/Congresso).

  • ARANGO, S. ; GALLEGO, V. ; Ospina-Medina, L ; SUAREZ-PUERTA, J. ; ALVAREZ, ANGELA ; CADAVID, ANGELA ; CARDONA-MAYA, W. . Espermicidas de origen natural, interesante alternativa contraceptiva.. 2013. (Apresentação de Trabalho/Congresso).

  • Alvarez, AM ; CADAVID, ANGELA P. ; CHAMLEY, LAWRENCE W. ; ABRAHAMS, VIKKI M. . Aspirin triggered lipoxin modulates human first trimester trophoblast response to antiphospholipid antibodies. 2013. (Apresentação de Trabalho/Congresso).

  • CADAVID, ANGELA ; ALVAREZ, ANGELA ; CHAIWANGYEN, WITTAYA ; MARKERT, U. R. . Effect of Heparin, Aspirin and Aspirin-triggered lipoxin on STAT-3 and ERK 1/2 activation on trophoblastic cells. 2012. (Apresentação de Trabalho/Congresso).

  • Alvarez, AM ; TORO, F. ; PARRA, S. ; MARKERT, U. R. ; CADAVID, ANGELA . Effect of aspirin and enoxaparin on serum levels of antiphospholipid antibodies and trophoblast proliferation. 2012. (Apresentação de Trabalho/Congresso).

  • ALVAREZ, ANGELA ; NEUBECK, S. ; CADAVID, ANGELA ; MARKERT, U. R. . Perfil proteíco de mujeres con Síndrome Antifosfolípido. 2010. (Apresentação de Trabalho/Seminário).

  • Alvarez, AM ; NEUBECK, S. ; CADAVID, ANGELA ; MARKERT, U. R. . Protein profile of women with antiphospholipid syndrome. 2010. (Apresentação de Trabalho/Congresso).

  • ALVAREZ-GÓMEZ, A. ; CARDONA-MAYA, W. ; CADAVID, A. . Actividad espermicida de los extractos de maracuyá y piña en los espermatozoides humanos. 2009. (Apresentação de Trabalho/Congresso).

Histórico profissional

Endereço profissional

  • Instituto Butantan, Divisão de Ciências Fisiológicas e Químicas, Serviço de Farmacologia. , Instituto Butantã, Butantã, 05503900 - São Paulo, SP - Brasil, Telefone: (11) 26279700

Experiência profissional

2015 - 2018

Universidad de Antioquia, UdeA

Vínculo: Professor Visitante, Enquadramento Funcional: Researcher

Outras informações:
Academic unit: Reproduction Group, Medicine School Position: Associated Researcher

2009 - 2018

Universidad de Antioquia, UdeA

Vínculo: Empleado, Enquadramento Funcional: Profesor adjunto (cátedra)

Outras informações:
Faculdade de Farmácia

2016 - 2017

Universidad de Antioquia, UdeA

Vínculo: Formal labor contract, Enquadramento Funcional: Researcher, Carga horária: 40

Outras informações:
Academic unit: Ophidism-Scorpionism Program. Academic Corporation to Tropical Pathologies Studies Position: Quality Control in Antivenom Development Project

2015 - 2016

Universidad de Antioquia, UdeA

Vínculo: Formal labor contract, Enquadramento Funcional: Researcher, Carga horária: 6

Outras informações:
Academic Unit: Academic Corporation to Tropical Pathologies Studies Position: Pharmaceutical Chemistry in Serpentarium of Ophidism-Scorpionism Program

2014 - 2014

Universidad de Valparaiso

Vínculo: Scientific training, Enquadramento Funcional: Academic visitor at Biomedical Res. Center, Carga horária: 40

Outras informações:
Academic visitor for the project: Evaluation of the effect of antiphospholipid antibodies on trophoblastic invasion and STAT-3 expression and activation. Source: International program of researchers interchange CONICYT (Chile) -COLCIENCIAS (Colombia)

2013 - 2013

Yale University

Vínculo: Scientific training, Enquadramento Funcional: Posgraduate Fellowship, Carga horária: 40

Outras informações:
Posgraduate Fellowship in Department of Obstetrics and Gynecology. School of Medicine. Doctorate project Source: COLCIENCIAS (Colombia)

2012 - 2012

Friedrich-Schiller-Universität Jena, UNI/Jena

Vínculo: Scientific training, Enquadramento Funcional: Acadmic visitor at Placenta Laboratory, Carga horária: 40

Outras informações:
Scientific traning at Placenta Laboratory. Department of Obstetrics and Gynecology, Friedrich-Schiller University AND Assistance to 3rd International Training in Reproductive Sciences and Techniques (3rd Jena InTReST). Source. DAAD.

2010 - 2010

Friedrich-Schiller-Universität Jena, UNI/Jena

Vínculo: Scientific training, Enquadramento Funcional: Academic visitor at Placenta Laboratory, Carga horária: 40

Outras informações:
Scientific traning at Placenta Laboratory. Department of Obstetrics and Gynecology, Friedrich-Schiller University AND Assistance to 2nd International Training in Reproductive Sciences and Techniques (2nd Jena InTReST). Source: DAAD