Martin Richard Faderl

Pós-doutorado

Formação complementar

Idiomas

Áreas de atuação

Produções bibliográficas

• BONFIGLIO, FERDINANDO BRUSCAGGIN, ALESSIO GUIDETTI, FRANCESCA TERZI DI BERGAMO, LODOVICO FADERL, MARTIN SPINA, VALERIA CONDOLUCI, ADALGISA BONOMINI, LUISELLA FORESTIERI, GABRIELA KOCH, RICARDO PIFFARETTI, DEBORAH PINI, KATIA PIROSA, MARIA CRISTINA CITTONE, MICOL GIULIA ARRIBAS, ALBERTO LUCIONI, MARCO GHILARDI, GUIDO WU, WEI ARCAINI, LUCA BAPTISTA, MARIA JOAO BASTIDAS, GABRIELA BEA, SILVIA BOLDORINI, RENZO BROCCOLI, ALESSANDRO BUEHLER, MARCO MATTEO , et al. CANZONIERI, VINCENZO CASCIONE, LUCIANO CERIANI, LUCA COGLIATTI, SERGIO CORRADINI, PAOLO DERENZINI, ENRICO DEVIZZI, LILIANA DIETRICH, SASCHA ELIA, ANGELA RITA FACCHETTI, FABIO GAIDANO, GIANLUCA GARCIA, JUAN FERNANDO GERBER, BERNHARD GHIA, PAOLO GOMES DA SILVA, MARIA GRITTI, GIUSEPPE GUIDETTI, ANNA HITZ, FELICITAS INGHIRAMI, GIORGIO LADETTO, MARCO LOPEZ-GUILLERMO, ARMANDO LUCCHINI, ELISA MAIORANA, ANTONINO MARASCA, ROBERTO MATUTES, ESTELLA MEIGNIN, VERONIQUE MERLI, MICHELE MOCCIA, ALDEN MOLLEJO, MANUELA MONTALBAN, CARLOS NOVAK, URBAN OSCIER, DAVID GRAHAM PASSAMONTI, FRANCESCO PIAZZA, FRANCESCO PIZZOLITTO, STEFANO RAMBALDI, ALESSANDRO SABATTINI, ELENA SALLES, GILLES SANTAMBROGIO, ELISA SCARFÒ, LYDIA STATHIS, ANASTASIOS STÜSSI, GEORG GEYER, JULIA T. TAPIA, GUSTAVO TARELLA, CORRADO THIEBLEMONT, CATHERINE TOUSSEYN, THOMAS TUCCI, ALESSANDRA VANINI, GIORGIO VISCO, CARLO VITOLO, UMBERTO WALEWSKA, RENATA ZAJA, FRANCESCO ZENZ, THORSTEN ZINZANI, PIER LUIGI KHIABANIAN, HOSSEIN CALCINOTTO, ARIANNA BERTONI, FRANCESCO BHAGAT, GOVIND CAMPO, ELIAS DE LEVAL, LAURENCE DIRNHOFER, STEFAN PILERI, STEFANO A. PIRIS, MIGUEL A. TRAVERSE-GLEHEN, ALEXANDRA TZANKOV, ALEXANDER PAULLI, MARCO PONZONI, MAURILIO MAZZUCCHELLI, LUCA CAVALLI, FRANCO ZUCCA, EMANUELE ROSSI, DAVIDE ; Genetic and phenotypic attributes of splenic marginal zone lymphoma. BLOOD , v. 139, p. 732-747, 2022.

• BRUSCAGGIN, ALESSIO ; DI BERGAMO, LODOVICO TERZI ; SPINA, VALERIA ; HODKINSON, BRENDAN ; FORESTIERI, GABRIELA ; BONFIGLIO, FERDINANDO ; CONDOLUCI, ADALGISA ; WU, WEI ; PIROSA, MARIA C. ; FADERL, MARTIN R. ; KOCH, RICARDO ; SCHAFFER, MICHAEL ; ALVAREZ, JOHN D. ; FOURNEAU, NELE ; GERBER, BERNHARD ; STUSSI, GEORG ; ZUCCA, EMANUELE ; BALASUBRAMANIAN, SRIRAM ; ROSSI, DAVIDE . Circulating tumor DNA for comprehensive noninvasive monitoring of lymphoma treated with ibrutinib plus nivolumab. BLOOD ADVANCES , v. 5, p. 4674-4685, 2021.

• BERGAMO, LODOVICO TERZI DI FORESTIERI, GABRIELA LOH, JUI WAN SINGH, AMARTYA SPINA, VALERIA ZUCCHETTO, ANTONELLA CONDOLUCI, ADALGISA FADERL, MARTIN KOCH, RICARDO BRUSCAGGIN, ALESSIO PINI, KATIA WU, WEI PIFFARETTI, DEBORAH BITTOLO, TAMARA TISSINO, ERIKA DE PAOLI, LORENZO DEAMBROGI, CLARA FRUSTACI, ANNA MARIA AUTORE, FRANCESCO MERLI, MICHELE SCARFÒ, LYDIA RASI, SILVIA PASSWEG, JAKOB MOIA, RICCARDO MARTINES, CLAUDIO , et al. GHIA, PAOLO CAVALLI, FRANCO ZUCCA, EMANUELE GERBER, BERNHARD GILLESSEN, SILKE STÜSSI, GEORG MONTILLO, MARCO PASSAMONTI, FRANCESCO GREGOR, MICHAEL LAURENTI, LUCA TEDESCHI, ALESSANDRA GAIDANO, GIANLUCA EFREMOV, DIMITAR GATTEI, VALTER KHIABANIAN, HOSSEIN ROSSI, DAVIDE ; CLL-358: Adaptation of Chronic Lymphocytic Leukemia to Ibrutinib Is Mediated by Epigenetic Plasticity of Residual Disease and Bypass Signaling via the MAPK Pathway. Clinical Lymphoma Myeloma & Leukemia , v. 21, p. S323-S324, 2021.

• CONDOLUCI, A. TERZI'DI'BERGAMO, L. FORESTIERI, G. MOIA, R. DEAMBROGI, C. DEODATO, M. FRUSTACI, A. M. MERLI, M. MATTARUCCHI, R. AUTORE, F. FAHRNI, G. SCARFÒ, L. GUSSETTI, D. BULIAN, P. ZANATTA, A. SPINA, V. FADERL, M. R. BRUSCAGGIN, A. PINI, K. PIFFARETTI, D. KOCH, R. PIROSA, M. C. CITTONE, M. G. PASSWEG, J. CAVALLI, F. , et al. ZUCCA, E. GERBER, B. GILLESSEN, S. STÜSSI, G. GATTEI, V. GHIA, P. GREGOR, M. LAURENTI, L. PASSAMONTI, F. TEDESCHI, A. GAIDANO, G. ROSSI, D. ; IBRUTINIB TOLERABILITY AND OUTCOME IN PATIENTS WITH HIGH-RISK CHRONIC LYMPHOCYTIC LEUKEMIA. HEMATOLOGICAL ONCOLOGY , v. 39, p. 252, 2021.

• WU, WEI BRUSCAGGIN, ALESSIO VALERA, ALEXANDRA FLOSPERGHER, ELENA BONFIGLIO, FERDINANDO SPINA, VALERIA TERZI-DI-BERGAMO, LODOVICO MOCCIA, ALDEN MOIA, RICCARDO RUFFINI, ALESSIA STATHIS, ANASTASIOS FADERL, MARTIN KOCH, RICARDO FORESTIERI, GABRIELA PINI, KATIA CONDOLUCI, ADALGISA PIROSA, MARIA CRISTINA GERBER, BERNHARD GILLESSEN, SILKE STÜSSI, GEORG GHIELMINI, MICHELE CAVALLI, FRANCO LUMINARI, STEFANO BOLDORINI, RENZO MAZZUCCHELLI, LUCA , et al. GAIDANO, GIANLUCA ROSSI, DAVIDE ZUCCA, EMANUELE ; Evaluation of the Different Stratification Models for POD24 Prediction in Patients with Follicular Lymphoma. BLOOD , v. 136, p. 24-25, 2020.

• FADERL, MARTIN ; KLEIN, FABIAN ; WIRZ, OLIVER F. ; HEILER, STEFAN ; ALBERTÍ-SERVERA, LLUCIA ; ENGDAHL, CORINNE ; ANDERSSON, JAN ; ROLINK, ANTONIUS . Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires. Frontiers in Immunology , v. 9, p. 252, 2018.

• BRASSEIT, J ; ALTHAUS-STEINER, E ; FADERL, M ; DICKGREBER, N ; SAURER, L ; GENITSCH, V ; DOLOWSCHIAK, T ; LI, H ; FINKE, D ; HARDT, W-D ; MCCOY, K D ; MACPHERSON, A J ; CORAZZA, N ; NOTI, M ; MUELLER, C . CD4 T cells are required for both development and maintenance of disease in a new mouse model of reversible colitis. Mucosal Immunology , v. 9, p. 689-701, 2016.

• FADERL, MARTIN ; NOTI, MARIO ; CORAZZA, NADIA ; MUELLER, CHRISTOPH . Keeping bugs in check: The mucus layer as a critical component in maintaining intestinal homeostasis. IUBMB LIFE , v. 67, p. 275-285, 2015.

• KNOCHENMUSS, R. ; MCCOMBIE, G. ; FADERL, M. . Ion Yields of Thin MALDI Samples:- Dependence on Matrix and Metal Substrate and Implications for Models. JOURNAL OF PHYSICAL CHEMISTRY A , v. 110, p. 12728-12733, 2006.

• FADERL, MARTIN RICHARD ; MUELLER, CHRISTOPH ; Zysset, Daniel ; BRASSEIT, J ; Kwong Chung, C.K.C. . Oral Mucosal Immunity and Microbiome. 11. ed. , 2019.

• FADERL, M. R. . Elucidating the role of the pathobiont Helicobacter typhlonius in a gnotobiotic mouse model of intestinal inflammation. 2017. (Apresentação de Trabalho/Simpósio).

• FADERL, M. R. . Quarterly meeting of the SNF Sinergia collaboration 2013-2017. 2017. (Apresentação de Trabalho/Comunicação).

• FADERL, M. R. . Colitis-associated changes in the gut microbiota: Cause or Consequence?. 2016. (Apresentação de Trabalho/Simpósio).

• FADERL, M. R. . A reversible mouse model of colitis allows to study the microbial, metabolic and immunological changes associated with remitting - relapsing inflammatory disorders in the intestine.. 2016. (Apresentação de Trabalho/Simpósio).

• FADERL, M. R. . A Mouse Model of Colitis to Study Microbial, Metabolic and Immunological Changes Associated with Remitting - Relapsing Inflammatory Disorders in the Intestine.. 2016. (Apresentação de Trabalho/Simpósio).

• FADERL, M. R. . A Mouse Model of Colitis to Study Microbial, Metabolic and Immunological Changes Associated with Remitting - Relapsing Inflammatory Disorders in the Intestine. 2016. (Apresentação de Trabalho/Congresso).

• FADERL, M. R. . Workshop on Immune Metabolism. 2016. (Apresentação de Trabalho/Seminário).

• FADERL, M. R. . Studying host-microbiota interactions in a gnotobiotic mouse model of reversible colitis. 2015. (Apresentação de Trabalho/Simpósio).

• FADERL, M. R. . Studying host-microbiota interactions in a gnotobiotic mouse model of reversible colitis. 2015. (Apresentação de Trabalho/Simpósio).

• FADERL, M. R. . Studying host-microbiota interactions in a gnotobiotic mouse model of reversible colitis. 2015. (Apresentação de Trabalho/Congresso).

• FADERL, M. R. . Dynamics of mucosal healing in a mouse model of reversible T cell colitis.. 2015. (Apresentação de Trabalho/Congresso).

• FADERL, M. R. . Studying host-microbiota interactions in a mouse model of reversible colitis.. 2014. (Apresentação de Trabalho/Congresso).

Projetos de pesquisa

• 2018 - Atual

  Discovery of genetic/epigenetic addictions in NOTCH2/KLF2-mutated lymphoma, Descrição: In the ongoing project, we aim to determine how genetic lesions that qualify as candidate driver genes in lymphoma, reprogram B cells. To address this question, we generate a genome edited lymphoma cell line and apply ATAC-seq, ChIP-seq, and mRNA-seq to extract the epigenetic signature driven by the selected genetic lesions. The purified epigenetic signature will then be validated in primary lymphoma samples. To validate the candidate genes as oncogenes a mouse model is set up to conditionally deregulate the genes of interest in B-cell populations. Here we contrast the murine B-cell differentiation trajectories imposed by each genetic make-up (RNA-seq, FACS). Further on, we will assess the penetrance of mouse lymphoma across the genetic setups and clinically validate the murine model as human lymphoma model by comparing their molecular phenotype Bonfiglio et al. Molecular subtypes of splenic marginal zone lymphoma (SMZL) - IELSG46 study, manuscript accepted for publication 2021. This contributed to the successful grant application financing the project ?Educating the spleen immune system to fight lymphoma? for a period of 3 years with a total budget of 367´300 CHF (n° KFS-5257-02-2021; Cancer Research Switzerland).. , Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (1) / Especialização: (2) / Mestrado acadêmico: (2) / Doutorado: (3) . , Integrantes: Martin Richard Faderl - Coordenador., Financiador(es): Swiss National Science Foundation - Bolsa.

Prêmios