Toshiaki Sunazuka

His research interests are in the areas of synthetic organic chemistry, medicinal, and bioorganic chemistry of bioactive microbial natural products. He has succeeded the total syntheses of 35 novel complex natural products including Lactacystin, Pyripyropenes, Macroshelides, Madindolines, Arisugasins, Paspalicine, so on to daon to date.He has also succeeded the development of Motilide (motilin like macrolide) which is on Phase II trial as a digestive medicine, and of ME5343 (Pyripyropene analogs) which will be commercialized as an insecticide around the world in 2014, and also of EM900 which is novel antiinflammatory macrolide without antibacterial activity. He is co-author of over 172 publications and 53 patents, and has delivered over 95 invited lecture including the international meetings. His research interests are 1) The determination of absolute stereochemistry of bioactive natural products 2) The total synthesis of bioactive natural products 3) The synthesis of bioactive natural product analogs and structure-activity relationships 4) Drug design by computer analysis 5) Bio-conversion by microbial or enzyme 6) Combinatorial chemistry 7) Development of new synthetic methods 8) Macrolide chemistry