Konradin Metze

CCurriculCuCCurricum vitae Konradin Metze : pathologist. graduated in Medicine, 1981 ( CurriFriedrich-Alexander University, Erlangen, Germany) PhD in 1982 ( thesis : Konzepte einer Pathologie der Hyperosmolarität, supervisor Prof Dr Götz Brandt, Institute of Pathology, Friedrich-Alexander University , Erlangen , Germany). 1982-1984 : Gerhard-Domagk-Institue of Pathology , University of Münster, Germany. 1984-1986 : Institute of Neuropathology , Bethel, Bielefeld, Germany. !986 - 1988 : Institute of Pathology , Klinikum Mannheim, Ruprecht-Karls-Universität, Heidelberg. since 1988 : Department of Pathology, Faculty of Medicine , University of Campinas ( UNICAMP), Brazil; Full professor (professor pleno) of the Postgraduate Course in Medical Pathophysiology ( UNICAMP) Lectures on general and special pathology, scientific methods and biostatistics. Research Interests : applying computerized image analysis and new technologies in microcopy. This includes :In particular : 1) Detection of invisible "hidden" information?in routinely prepared cytologic or histologic slides by texture analysis with inhouse developed computer programs based on the concepts of entropy, fractality, co-occurrence matrix etc.; 2..Generation of virtual microscopic images with the contrast created by differences of physicochemical characteristics of tissues, e.g. fluorescence lifetime imaging and multiphoton microscopy (in collaboration with INCT INFABIC) 3. Creation of diagnostic algorithms and prognostic mathematical models based on computerized image analysis or other clinical and laboratory data. 167 publications indexed in PUBMED, 179 in SCOPUS, 246 in WEBOFKNOWLEDGE ( 168 withou meeting summaries or abstracts). 2604 citations with Hirsch index h = 26 according to WEBOFKNOWLEDGE, 4085 with h=36 according to Google Scholar ( on 10/01/2020) Member of the editorial /advisory boards of Cellular Pathology Pathology Research and Practice,; Section Editor of Diagnostic Pathology and Academic Editor of PLOS ONE Married to Irene Gyöngyver Heidemarie Lorand-Metze.

Informações coletadas do Lattes em 02/06/2022

Acadêmico

Formação acadêmica

Doutorado em medicina

1977 - 1982

FAU Erlangen-Nürnberg
Título: Konzepte einer Pathologie der Hyperosmolarität
Orientador: Prof Dr Götz Brandt

Graduação em medicina

1974 - 1981

FAU Erlangen -Nürnberg

Pós-doutorado

1982 - 1984

Pós-Doutorado. , Gerhard Domagk Institut für Pathologie , Univ .Münster, Alemanha, UNIMÜNSTER, Alemanha. , Grande área: Ciências da Saúde

Idiomas

Bandeira representando o idioma Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Bandeira representando o idioma Espanhol

Compreende Razoavelmente, Fala Pouco, Lê Razoavelmente, Escreve Pouco.

Bandeira representando o idioma Alemão

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Latim

Compreende Razoavelmente, Fala Pouco, Lê Razoavelmente, Escreve Pouco.

Organização de eventos

METZE, K. ; KAYSER, K.Klaus Kayser ; Constantino Tsallis ; LEITE, N. J. . Aplicação Interdisciplinar das Entropias de Informação ( Forum de Saúde). 2006. (Outro).

Orientou

Erika Said Abu Egal

Início: 2017; Universidade Estadual de Campinas, Conselho Nacional de Desenvolvimento Científico e Tecnológico;

Fernanda Aparecida Borges da Silva

"Utilização do método fluorescente leifetime imaging microscopy na identificação de células hematopoiéticas em esfregaços de medula óssea, sem uso de corantes"; ; 2018; Dissertação (Mestrado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Ana Paula Racanelli Bovo

APLICAÇÃO DO MÉTODO ?FLUORESCENCE LIFETIME IMAGING MICROSCOPY? (FLIM) EM EXSUDATOS NO PULMÃO; 2015; Dissertação (Mestrado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Joyce Rico Vido Marques

Análise dos parâmetros morfométricos e textura da cromatina dos mieloblastos nas síndromes mielodisplásicas; 2011; Dissertação (Mestrado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Daniela Peixoto Ferro

Fractalidade da cromatina como fator prognósotico em mieloma múltiplo; 2010; Dissertação (Mestrado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Gislaine Vieira

Análise da arquitetura da aorta de pacientes normotensos e hipertensos; 2009; Dissertação (Mestrado em Fisiopatologia Médica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Karime Cury Scarpelli

Análise da estrutura sintática como fator preditivo em TVTC em terapia com vincristina; 2008; Dissertação (Mestrado em Ciências Médicas) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Gustavo Ligeri Pereira do Prado

Estudo da textura nuclear em ratos Wistar após intoxicação por chumbo; 2008; Dissertação (Mestrado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Maria Luiza de Castro Ramos Valladão

Dados clínicos, morfométricos e textura nuclear como fatores prognósticos e preditivos no tumor venéreo trasmissível canino; 2007; Dissertação (Mestrado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

MARIA OXANA POLONI RYBKA

Subpopulação de células estromatosas que circundam o carci noma basocelular: Valor Prognóstico na Recidiva; ; 2006; Dissertação (Mestrado em Fisiopatologia Médica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Valcinir Bedin

Parmetros de textura da cromatina como fator prognóstico em carcinoma basocelular?; 2004; Dissertação (Mestrado em Ciências Médicas) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

RANDALL LUIS ADAM

Análise Espectral Usando a Transformada de Fourier Discreta para o Estudo de Núcleos Celulares: Elaboração de Programa e Aplicação no Desenvolvimento do Coração; ?; 2002; Dissertação (Mestrado em Ciências Médicas) - Universidade Estadual de Campinas, Fundação de Amparo à Pesquisa do Estado de São Paulo; Orientador: Konradin Metze;

José Augusto Hart Madureira Filho

Comparação entre Técnicas Morfométricas Aplicadas ao Epitélio Vaginal após Uso Prolongado do Contraceptivo Injetável Acetato de Medroxiprogesterona de Depósito; 2001; Dissertação (Mestrado em Ciências Médicas) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Ângela Cury de Mello Sá

Uso da Saponina em Fixadores para Exame Citológico; 2001; Dissertação (Mestrado em Ciências Médicas) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Amilcar Castro de Mattos

Alterações Semelhantes à Displasia Fibromuscular (ASDFM) em Vasos Mesentéricos: Um Fenômeno de Remodelamento?; 2001; Dissertação (Mestrado em Ciências Médicas) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Maria Elvira Pizzigati Correa ( co-orientação )

A Mucosa Oral e Glândulas Salivares Acessórias Na Doença de Enxerto Contra O Hospedeiro Crônico Após Tmo; 1999; Dissertação (Mestrado em Anatomia Patológica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Fatima Neder

Caracterização das Regiões Organizadoras do Nucléolo No Miocárdio Durante O Desenvolvimento do Coração; ; 1997; Dissertação (Mestrado em Anatomia Patológica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Erni Maria Mancini Cia

Técnica de Agnor-Um Auxílio No Diagnóstico Diferencail Em Citologia Urinária; 1997; Dissertação (Mestrado em Anatomia Patológica) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Marcelo Addas de Carvalho

Regiões Organizadoras de Nucléolos Como Índice de Proliferação Celular Nas Leucemias Agudas; 1997; Dissertação (Mestrado em Ciências Médicas) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Adriana Azevedo Coutinho Mariuzzo

Estudo Histológico Comparativo da Reparação de Lesões Provocadas de Rato Pelo Laser de Co2 Aplicado Em Condições de Enregia Constante Variando Tempo e Potência; ; 1997; Dissertação (Mestrado em Neurociencias) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Luciana Nathan

Envolvimento dos Canais de Cálcio Voltagem -Dependentes e da Endotelina Nas Alterações Cardiovasculares Iduzidas Pelo Bloqueio Crônico da Sínteses de Óxido Nítrico; ; 1997; Dissertação (Mestrado em Farmacologia) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Daniela Peixoto Ferro

APLICAÇÃO DA BIOFOTÔNICA PARA O ESTUDO DE CICATRIZES; 2015; Tese (Doutorado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Maria Luiza de Castro Ramos Valladão

Remodelamento do tumor venéreo transmissível durante o tratamento; 2012; Tese (Doutorado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Gislaine Vieira Damiani

Análise computacional de fibras elásticas e colágenas da aorta humana; 2012; Tese (Doutorado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Renata de Marchi Triglia

Aspectos preditivos da progressão da lesão de NIC 1 em bió-psias do colo uterino: estudo comparativo entre o método da hibridização in situ e a expressão do Ki67, avaliada por mé-todos morfológicos quantitativos",; 2010; Tese (Doutorado em Ciências Médicas) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Valcinir Bedin

"Relação entre textura microscópica celular e dados clíni- cos no melanoma maligno",; 2010; Tese (Doutorado em Ciências Médicas) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Rafael de Camargo Penteado Borges

"Efeito do exercício físico sobre a expressão de AT1R e AT2R no ventrículo esquerdo, aorta e rim, e sua implicação no sistema cardiovascular e manipulação tubular de sódio em SHR",; 2010; Tese (Doutorado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Lilian Barreto Elston

"Concordância entre observadores e importância prognóstica das variáveis de Patnaik, Ehler & MacEwen e da análise sintática estrutural de Mastocitoma Cutâneo Canino"; 2009; Tese (Doutorado em Fisiopatologia Médica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Rita de Cássia Ferreira

Contribuição da análise de textura do núcleo celular para o diagnóstico diferencial de lesões foliculares da tireóide -comparação com marcadores imunoisto químicos; 2007; Tese (Doutorado em Ciências Médicas) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Maria Luiza de Castro Ramos Valladão

Remodelamento em Tumor Venéreo Transmissível Canino; 2007; Tese (Doutorado em Fisiopatologia Medica) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

RANDALL LUIS ADAM

Análise granulométrica da textura de núcleos celulares; 2006; Tese (Doutorado em Fisiopatologia Médica) - Universidade Estadual de Campinas, Fundação de Amparo à Pesquisa do Estado de São Paulo; Orientador: Konradin Metze;

Mariam Patrícia Auada Souto

Estudo clínico-molecular e análise da textura epidérmica de pacientes com sindrome de Sjögren-Larsson; 2006; Tese (Doutorado em Ciências Médicas) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Manoel Baldoino Leal Filho

CONTRIBUIÇÃO AO ESTUDO DAS ALTERAÇÕES DA MEDULA ESPINHAL EM MODELO EXPERIMENTAL DE LESÃO TRAUMÁTICA NA FASE AGUDA; ; 2004; Tese (Doutorado em Ciências Médicas) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Miriam Elias Cavallini

Lesões agudas da mucosa gástrica de ratos por agentes an- tiinflamatórios não esteroidais: estudo experimental compa- rativo entre a indometacina e celecoxib e a citoproteção co-momeprazol e o misoprosto; 2002; Tese (Doutorado em Ciências da Cirurgia) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

José Telmo Valença Júnior

Caracterização das AgNORS no Hepatocarcinoma: Análise Morfológica e Quantitativa e Comparação com a Graduação de Edmondson-Steiner; 2001; Tese (Doutorado em Ciências Médicas) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Jamil Jorge Abou Mourad

Uso de Solução M&G para Prevenção da Lesão endotelial durante a reperfusão, após iIsquemia arterial aguda; 2001; Tese (Doutorado em Ciências da Cirurgia) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Ivan Felizardo Contrera Toro

Fatores Prognósticos Clínicos-Cirúrgicos e Histológicos de Sobrevida em Pacientes com Carcinoma Não-Pequenas Células de Pulmão; ; 2000; Tese (Doutorado em Ciências da Cirurgia) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Rosana Celestina Morandin

Alterações da Aorta em Ratas Portadoras de Neoplasia; 2000; Tese (Doutorado em Ciências Médicas) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Alair Assis

Aspectos Anátomo - Clínicos da Doença Raiva em Animais Domésticos; 2000; Tese (Doutorado em Ciências Médicas) - Universidade Estadual de Campinas,; Orientador: Konradin Metze;

Heitor Moreno Jr

Inibição da Síntese de Óxido Nítrico Em Ratos : Efeitos Sobre Morfologia e A Função Cardíaca; 1995; Tese (Doutorado em Farmacologia) - Universidade Estadual de Campinas,; Coorientador: Konradin Metze;

Mayara Tabai

A analise sintatica estrutural pode ajudar no diagnostico diferencial entre ceratoacantoma e carcinoma epidermoide bem diferenciado em biopsias pequenas?; 2012; Iniciação Científica; (Graduando em Medicina) - Universidade Estadual de Campinas, Fundação de Amparo à Pesquisa do Estado de São Paulo; Orientador: Konradin Metze;

Produções bibliográficas

  • FLORINDO, JOAO B. ; Metze, Konradin . A cellular automata approach to local patterns for texture recognition. EXPERT SYSTEMS WITH APPLICATIONS , v. 179, p. 115027-115027, 2021.

  • SILVA, FERNANDA APARECIDA BORGES ; RACANELLI, ANA PAULA ; LORAND'METZE, IRENE ; Metze, Konradin . Fluorescence lifetime imaging is able to recognize different hematopoietic precursors in unstained routine bone marrow films. CYTOMETRY PART A , v. 99, p. 641-646, 2021.

  • FLORINDO, JOAO ; Metze, Konradin . Using Non-Additive Entropy to Enhance Convolutional Neural Features for Texture Recognition. Entropy , v. 23, p. 1259-1259, 2021.

  • CENI-SILVA, VITÓRIA ; PAGNANO, KÁTIA ; DUARTE, GISLAINE ; PELLEGRINI, MARINA ; DUARTE, BRUNO ; Metze, Konradin ; Lorand-Metze, Irene . Using Antigen Expression of Leukemic Cells for a Fast Screening of Acute Promyelocytic Leukemia by Flow Cytometry. Diagnostics , v. 11, p. 1988-1988, 2021.

  • Kaduk B ; METZE, K. ; Schmidt PF ; Brandt G . Scoring of PD-L1 positivity: Are we analyzing enough cells?. CANCER CYTOPATHOLOGY , v. 128, p. 424-424, 2020.

  • BORGES DA SILVA, FERNANDA A. ; LORAND'METZE, IRENE ; Metze, Konradin . Chédiak-Higashi syndrome approached by several different microscopy imaging technologies. BRITISH JOURNAL OF HAEMATOLOGY , v. 189, p. 1001-1001, 2020.

  • VIDO-MARQUES, J. R. ; REIS-ALVES, S. C. ; SAAD, S. T. O. ; METZE, K. ; LORAND-METZE, I. . A simple score derived from bone marrow immunophenotyping is important for prognostic evaluation in myelodysplastic syndromes. Scientific Reports , v. 10, p. 20281, 2020.

  • Metze, Konradin ; Adam, Randall ; FLORINDO, JOÃO BATISTA . The fractal dimension of chromatin - a potential molecular marker for carcinogenesis, tumor progression and prognosis. Expert Review of Molecular Diagnostics , v. 19, p. 299-312, 2019.

  • EGAL, E.S. ; MARIANO, F.V. ; ALTEMANI, A.M. ; METZE, K. . Age and adenoma size are independent risk factors for the development of carcinoma ex pleomorphic adenoma. ORAL ONCOLOGY , v. 84, p. 106-107, 2018.

  • Metze, Konradin . Lowering the p-value from 0.05 to 0.005 conflicts with the 3R rules - an advocacy for alternatives to hypothesis testing with the p-value approach. ALTEX-Alternatives to Animal Experimentation , v. 35, p. 516-517, 2018.

  • Metze, Konradin ; REIS-ALVES, SUIELLEN C. ; Lorand-Metze, Irene . The World Health Organisation classification of myelodysplastic syndromes contains prognostically relevant information beyond the prognostic scores IPSS-R or WPSS. EUROPEAN JOURNAL OF CANCER , v. 72, p. 266-268, 2017.

  • VIEIRA-DAMIANI, GISLAINE ; Lage, Denise ; CHRISTOFOLETTI DALDON, PATRÍCIA ÉRICA ; TIBÚRCIO ALVES, CAROLINE ROMANELLI ; Cintra, Maria Letícia ; Metze, Konradin ; ADUR, JAVIER ; PELEGATI, VITOR B. ; CARVALHO, HERNANDES F. ; CESAR, CARLOS LENZ . Idiopathic atrophoderma of Pasini and Pierini: A case study of collagen and elastin texture by multiphoton microscopy. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY , v. 77, p. 1, 2017.

  • OLIVEIRA, ANITA F. ; TANSINI, ALINE ; VIDAL, DANIEL O. ; LOPES, LUIZ F. ; Metze, Konradin ; Lorand-Metze, Irene . Characteristics of the phenotypic abnormalities of bone marrow cells in childhood myelodysplastic syndromes and juvenile myelomonocytic leukemia. PEDIATRIC BLOOD & CANCER , v. 64, p. e26285, 2017.

  • Lorand-Metze, I. ; LONGHINI, A. L. ; OLIVEIRA-DUARTE, G. ; CORREIA, R. P. ; SANTOS-SILVA, M. C. ; YAMAMOTO, M. ; SANDES, A. F. ; OLIVEIRA, A. F. ; SOUTO, E. X. ; IKOMA, M. R. V. ; PEREIRA-CUNHA, F. G. ; BELTRAME, M. ; METZE, K. . Normal variation of bone marrow B-cell precursors according to age - reference ranges for studies in myelodysplastic syndromes in Brazil. CYTOMETRY PART B-CLINICAL CYTOMETRY , v. 1, p. 10.1002/cyt, 2017.

  • Metze, Konradin ; REIS-ALVES, SUIELLEN C. ; Lorand-Metze, Irene . Monocyte phenotypic aberrancies are an unfavorable prognostic factor in patients with myelodysplastic syndromes and low IPSS-R scores. Cellular Immunology (Print) , v. 1, p. 1-2, 2016.

  • Metze, Konradin ; REIS-ALVES, SUIELLEN C. ; LORAND-METZE, IRENE G. H. . Presence of B-cell precursors in bone marrow is a favorable independent prognostic factor for overall survival in patients with myelodysplastic syndromes. American Journal of Hematology (Print) , v. 1, p. 1-2, 2016.

  • MORENO, CAROLINA ARAUJO ; Metze, Konradin ; LOMAZI, ELIZETE APARECIDA ; BERTOLA, DÉBORA ROMEO ; BARBOSA, RICARDO HENRIQUE ALMEIDA ; COSENTINO, VIVIANA ; SOBREIRA, NARA ; CAVALCANTI, DENISE PONTES . Visceral myopathy: Clinical and molecular survey of a cohort of seven new patients and state of the art of overlapping phenotypes. American Journal of Medical Genetics. Part A , v. 1, p. 1-5, 2016.

  • Florence, Michelle Etienne Baptistella ; Massuda, Juliana Yumi ; Soares, Tânia Cristina Benetti ; STELINI, RAFAEL FANTELLI ; POPPE, LIDIA MARILIA ; Bröcker, Eva-Bettina ; Metze, Konradin ; Cintra, Maria Letícia ; Souza, Elemir Macedo de . p53 Immunoexpression in Stepwise Progression of Cutaneous Squamous Cell Carcinoma and Correlation with Angiogenesis and Cellular Proliferation. Pathology, Research and Practice (Print) , v. 07, p. 001-006, 2015.

  • WATANABE, ISABELA C. ; MAGALHÃES, RENATA F. ; DE MORAES, APARECIDA M. ; STELINI, RAFAEL F. ; CINTRA, GEÓRGIA F. ; Metze, Konradin ; Cintra, Maria L. . Keratoacanthoma and Keratoacanthoma-Like Squamous Cell Carcinoma. Medicine (Baltimore, Md.) , v. 94, p. e934, 2015.

  • REGO, MN ; METZE, K ; Lorand-Metze, I . Low educational level but not low income impairs the achievement of cytogenetic remission in chronic myeloid leukemia patients treated with imatinib in Brazil. Clinics (USP. Impresso) , v. 70, p. 322-325, 2015.

  • Reis-Alves, Suiellen C ; TRAINA, FABIOLA ; Metze, Konradin ; Lorand-Metze, Irene . Improving the differential diagnosis between myelodysplastic syndromes and reactive peripheral cytopenias by multiparametric flow cytometry: the role of B-cell precursors. Diagnostic Pathology , v. 10, p. 44, 2015.

  • Lorand-Metze, Irene ; OLIVEIRA-DUARTE, GISLAINE B. ; Metze, Konradin . Imbalance between proliferation and in vitro apoptosis rates predicts progression in chronic lymphocytic leukemia. Cytometry. Part B, Clinical Cytometry , v. 0000, p. n/a-n/a, 2015.

  • PEREIRA-CUNHA, F. G. ; DUARTE, A. S. S. ; REIS-ALVES, S. C. ; OLALLA SAAD, S. T. ; METZE, K. ; Lorand-Metze, I. ; LUZO, Â. C. M. . Umbilical cord blood CD34 + stem cells and other mononuclear cell subtypes processed up to 96h from collection and stored at room temperature maintain a satisfactory functionality for cell therapy. Vox Sanguinis (Basel. 1956) , v. 108, p. 72-81, 2015.

  • REIS, E.R. ; METZE, K. ; NICOLA, E.M.D. ; NICOLA, J.H. ; BORISSEVITCH, I.E. . Photodynamic activity of protoporphyrin IX in Harderian glands of Wistar rats: Monitoring by gland fluorescence. Journal of Luminescence , v. 137, p. 32-36, 2013.

  • Metze, Konradin . Fractal dimension of chromatin: potential molecular diagnostic applications for cancer prognosis. Expert Review of Molecular Diagnostics , v. 13, p. 719-735, 2013.

  • PORTO, MARCOVAN ; DE OLIVEIRA, MARCO ANTONIO ; PISSINATTI, LORENZO ; RODRIGUES, RENATA LOPES ; ROJAS-MOSCOSO, JULIO ALEJANDRO ; COGO, JOSÉ CARLOS ; Metze, Konradin ; Antunes, Edson ; NAHOUM, CÉSAR ; MÓNICA, FABÍOLA Z. ; de Nucci, Gilberto . The Evolutionary Implications of Hemipenial Morphology of Rattlesnake Crotalus durissus terrificus (Laurent, 1768) (Serpentes: Viperidae: Crotalinae). Plos One , v. 8, p. e66903, 2013.

  • REIS-ALVES, SUIELLEN C. ; TRAINA, FABÍOLA ; HARADA, GUILHERME ; CAMPOS, PAULA M. ; SAAD, SARA T. O. ; Metze, Konradin ; Lorand-Metze, Irene . Immunophenotyping in Myelodysplastic Syndromes Can Add Prognostic Information to Well-Established and New Clinical Scores. Plos One , v. 8, p. e81048, 2013.

  • MENEZES, FABIO HUSEMANN ; SILVEIRA, THIAGO DO CARMO ; SILVEIRA, SANDRA APARECIDA FERREIRA ; SALLES-CUNHA, SERGIO XAVIER ; Metze, Konradin ; MENEZES, ANA SILVIA CARVALHO DE . Comparacoes preliminares entre a histologia virtual ultrassonografica in vivo e os achados histopatologicos da placa carotidea produto de endarterectomia. Jornal Vascular Brasileiro (Impresso) , v. 12, p. 193-201, 2013.

  • SOUSA, RAFAEL ARROMBA DE ; SABARENSE, CÉPHORA MARIA ; PRADO, GUSTAVO L.P. ; Metze, Konradin ; CADORE, SOLANGE . Lead biomonitoring in different organs of lead intoxicated rats employing GF AAS and different sample preparations. Talanta (Oxford) , v. 104, p. 90-95, 2013.

  • DE MELLO, MARIANA RB ; MELLO, MRB ; PAGNANO, K. B. B. ; COSTA, FF ; LORAND-METZE, IRENE GYONGYVER H. ; ALBANEZ, KRIZZIA B ; ALBUQUERQUE, DULCINEIA M ; PEREIRA-CUNHA, FERNANDA GONÇALVES ; COSTA, FERNANDO F ; PAGNANO, KATIA BB ; Lorand-Metze, Irene ; Metze, Konradin . Molecular characteristics and chromatin texture features in acute promyelocytic leukemia. Diagnostic Pathology , v. 28, p. 75, 2012.

  • Lage, Denise ; JULIANO, PRISCILA BIANCHINI ; Metze, Konradin ; Souza, Elemir Macedo de ; Cintra, Maria Letícia . Lichen planus and lichenoid drug-induced eruption: a histological and immunohistochemical study. International Journal of Dermatology , v. 51, p. 1199-1205, 2012.

  • METZE, K. ; CINTRA, M. L. . Are there relevant differences in the basic geometric structure of the nuclear chromatin between keratoacanthoma and keratoacanthoma-like squamous cell carcinoma?. Histopathology (online) , v. 61, p. 62, 2012.

  • Metze, Konradin . Dichotomizing Continuous Prognostic Factors Can Cause Paradoxical Results in Survival Models. Journal of the American College of Surgeons , v. 212, p. 132-134, 2011.

  • Metze, Konradin . Re: Tumor Infiltrated Hilar and Mediastinal Lymph Nodes are an Independent Prognostic Factor for Decreased Survival After Pulmonary Metastasectomy in Patients With Renal Cell Carcinoma. The Journal of Urology , v. 186, p. 349-350, 2011.

  • Florence, Michelle Etienne Baptistella ; Massuda, Juliana Yumi ; Bröcker, Eva-Bettina ; Metze, Konradin ; Cintra, Maria Letícia ; Souza, Elemir Macedo de . Angiogenesis in the progression of cutaneous squamous cell carcinoma: an immunohistochemical study of endothelial markers. Clinics (USP. Impresso) , v. 66, p. 465-468, 2011.

  • Borges-Almeida, Eliane ; Milanez, Helaine MBPM ; Vilela, Maria Marluce S ; Cunha, Fernanda GP ; Abramczuk, Beatriz M ; Reis-Alves, Suiellen C ; Metze, Konradin ; Lorand-Metze, Irene . The impact of maternal HIV infection on cord blood lymphocyte subsets and cytokine profile in exposed non-infected newborns. BMC Infectious Diseases (Online) , v. 11, p. 38, 2011.

  • Vido, Joyce R ; Adam, Randall L ; Lorand-Metze, Irene GH ; Metze, Konradin . Computerized texture analysis of atypical immature myeloid precursors in patients with myelodysplastic syndromes: an entity between blasts and promyelocytes. Diagnostic pathology , v. 6, p. 93, 2011.

  • Pereira, Daniel José ; Moreira, Marcos Mello ; Paschoal, Ilma Aparecida ; Martins, Luiz Cláudio ; Metze, Konradin ; Moreno Junior, Heitor . Embolia pulmonar quase fatal, um modelo experimental. Revista Brasileira de Cirurgia Cardiovascular (Impresso) , v. 26, p. 462-468, 2011.

  • Metze, Konradin . Pitfalls in the assessment of prognostic factors. Lancet Oncology , v. 12, p. 1095-1096, 2011.

  • Lage, Denise ; Pimentel, Vanessa N. ; Soares, Tania C. B. ; Souza, Elemir M. ; Metze, Konradin ; Cintra, Maria L. . Perforin and granzyme B expression in oral and cutaneous lichen planus - a comparative study. Journal of Cutaneous Pathology , v. 38, p. 973-978, 2011.

  • FERRO, DANIELA P. ; FALCONI, MONICA A. ; Adam, Randall L. ; ORTEGA, MANOELA M. ; LIMA, CARMEN P. ; de Souza, Carmino A. ; Lorand-Metze, Irene ; Metze, Konradin . Fractal Characteristics of May-Grünwald-Giemsa Stained Chromatin Are Independent Prognostic Factors for Survival in Multiple Myeloma. Plos One , v. 6, p. e20706-e20706, 2011.

  • Bedin, Valcinir ; Adam, Randall L ; de Sa, Bianca CS ; Landman, Gilles ; Metze, Konradin . Fractal dimension of chromatin is an independent prognostic factor for survival in melanoma. BMC Cancer (Online) , v. 10, p. 260, 2010.

  • Scarpelli, Karime C. ; Valladão, Maria L. ; Metze, Konradin . Predictive factors for the regression of canine transmissible venereal tumor during vincristine therapy. The Veterinary Journal , v. 183, p. 362-363, 2010.

  • Metze, Konradin ; Adam, Randall L. ; Ferreira, Rita C. . Robust variables in texture analysis. Pathology (Sydney) , v. 42, p. 609-610, 2010.

  • Pimentel, Vanessa Nascimento ; De Matos, Lissa Sabino ; Soares, Tânia Cristina Benetti ; Adam, Randall ; Metze, Konradin ; Correa, Maria Elvira Pizzigatti ; De Souza, Cármino Antonio ; Cintra, Maria Letícia . Perforin and granzyme B involvement in oral lesions of lichen planus and chronic GVHD. Journal of Oral Pathology and Medicine , p. no-no, 2010.

  • Lourenço, Gustavo J. ; Lorand-Metze, Irene ; Delamain, Marcia T. ; Miranda, Eliana C. M. ; Kameo, Rodolfo ; Metze, Konradin ; Lima, Carmen S. P. . Polymorphisms of glutathione S-transferase mu 1, theta 1, and pi 1 genes and prognosis in Hodgkin lymphoma. Leukemia & Lymphoma (Print) , p. 1-7, 2010.

  • Metze, Konradin ; Ferreira, Rita C. ; Adam, Randall L. . Classification of thyroid follicular lesions based on nuclear texture features-Lesion size matters. Cytometry. Part A , p. n/a-n/a, 2010.

  • Metze, Konradin . Fractal dimension of chromatin and cancer prognosis. Epigenomics , v. 2, p. 601-604, 2010.

  • Metze, Konradin . Bureaucrats, researchers, editors, and the impact factor: a vicious circle that is detrimental to science. Clinics (USP. Impresso) , v. 65, p. 937-940, 2010.

  • DEMARCHITRIGLIA, R ; METZE, K ; ZEFERINO, L ; LUCCIDEANGELOANDRADE, L . HPV in situ hybridization signal patterns as a marker for cervical intraepithelial neoplasia progression. Gynecologic Oncology , v. 112, p. 114-118, 2009.

  • Metze, Konradin . The Association Between Overall Survival and the Total Number of Dissected Lymph Nodes: An Artifact Caused by the Surgical Pathologist?. Annals of Surgery , v. 249, p. 693-694, 2009.

  • Metze, Konradin ; Adam, Randall L. . Is There a Reliable Minimum Number of Lymph Nodes for T1 and T2 Colon Cancer?. Digestive Diseases and Sciences , v. 54, p. 914-915, 2009.

  • Metze, Konradin . Lymph Node Yield as a Prognostic Factor in Cancer StudiesDue to Undersampling of Tumor-Free Lymph Nodes at Higher N Stages?. Annals of Surgical Oncology , v. 16, p. 1080-1082, 2009.

  • Elston L ; Sueiro FA ; Cavalcanti J, ; Metze, Konradin . The importance of the mitotic index as a prognostic factor for canine cutaneous mast cell tumors - a validation study.. Veterinary Pathology , v. 46, p. 362-364, 2009.

  • Metze, Konradin . Pitfalls in prognostic factor studies. Journal of Cutaneous Pathology , v. 36, p. 713-714, 2009.

  • Pinheiro, Ronald Feitosa ; Metze, Konradin ; Silva, Maria Regina Régis ; de Lourdes Lopes Ferrari Chauffai, Maria . The ambiguous role of interferon regulatory factor-1 (IRF-1) immunoexpression in myelodysplastic syndrome. Leukemia Research , v. 33, p. 1308-1312, 2009.

  • REIS, S. ; TRAINA, F. ; METZE, K. . VARIATION OF BONE MARROW CD34+ CELL SUBSETS IN MYELODYSPLASTIC SYNDROMES ACCORDING TO WHO TYPES. Neoplasma , v. 56, p. 435-440, 2009.

  • METZE, K. ; ADAM, R. L. ; Vido JR ; Lorand-Metze, I . The Influence of Staining Characteristics on Nuclear Texture Features in Cytology. Analytical and Quantitative Cytology and Histology , v. 31, p. 241-245, 2009.

  • Ferreira, Rita C. ; Ward, Laura S. ; Adam, Randall L. ; Leite, Neucimar J. ; Metze, Konradin ; Matos, Patrícia S. de . Contribuição da análise de textura do núcleo celular para o diagnóstico diferencial de lesões foliculares da tireoide: comparação com marcadores imunoistoquímicos. Arquivos Brasileiros de Endocrinologia e Metabologia (Impresso) , v. 53, p. 804-810, 2009.

  • De Capitani, Eduardo Mello ; Schweller, Marcelo ; Silva, Cristiane Mendes da ; Metze, Konradin ; Cerqueira, Elza Maria Figueiras Pedreira de ; Bértolo, Manoel Barros . Pneumoconiose reumatoide (síndrome de Caplan) com apresentação clássica. Jornal Brasileiro de Pneumologia (Impresso) , v. 35, p. 942-946, 2009.

  • METZE, K. . José Lopes de Faria. Der Pathologe (Heidelberg) , v. 30, p. 247-248, 2009.

  • METZE, K ; Lorand-Metze, Irene ; Leite, Neucimar J. ; Adam, Randall L . Goodness-of-fit of the fractal dimension as a prognostic factor. Cellular Oncology , v. 31, p. 503-504, 2009.

  • Metze, Konradin ; Adam, Randall L. . Intrinsic Problems of the Nuclear Shape Factor Analysis. Diseases of the Colon & Rectum , v. 52, p. 1523, 2009.

  • HADDAD, P ; MARTINS, T ; DSOUZALI, L ; LI, L ; METZE, K ; ADAM, R ; KNOBEL, M ; ZANCHET, D . Structural and morphological investigation of magnetic nanoparticles based on iron oxides for biomedical applications. Materials Science & Engineering. C, Biomimetic Materials, Sensors and Systems , v. 28, p. 489-494, 2008.

  • LORANDMETZE, I ; CALIFANI, S ; RIBEIRO, E ; LIMA, C ; METZE, K . The prognostic value of maturation-associated phenotypic abnormalities in myelodysplastic syndromes. Leukemia Research , v. 32, p. 211-213, 2008.

  • Rybka, Maria O. ; Cintra, Maria L. ; de Souza, Elemir M. ; METZE, K. . Density of dendritic cells around basal cell carcinomas is related to tumor size, anatomical site and stromal characteristics, and might be responsible for the response to topical therapy. International Journal of Dermatology , v. 47, p. 1240-1244, 2008.

  • Costa, A. F. ; Demasi, A. P. D. ; Bonfitto, V. L. L. ; Bonfitto, J. F. L. ; Furuse, C. ; Araújo, V. C. ; METZE, K. ; Altemani, A. . Angiogenesis in salivary carcinomas with and without myoepithelial differentiation. Virchows Archiv , v. 453, p. 359-367, 2008.

  • Metze, Konradin ; Ferreira, Rita C. ; Adam, Randall L. ; Leite, Neucimar J. ; Ward, Laura S. ; Matos, Patrícia S. . Chromatin Texture is Size Dependent in Follicular Adenomas But Not in Hyperplastic Nodules of the Thyroid. World Journal of Surgery , v. 32, p. 2744-2746, 2008.

  • Adam, Randall L. ; Leite, Neucimar J. ; METZE, K . Image preprocessing improves Fourier-based texture analysis of nuclear chromatin.. Analytical and Quantitative Cytology and Histology , v. 39, p. 175-184, 2008.

  • Marinho, Vanessa Fortes Zschaber ; Metze, Konradin ; Sanches, Fernanda Squárcio Fernandes ; Rocha, Gislene Fátima Silva ; Gobbi, Helenice . Marcadores moleculares em câncer de mama preditivos de metástases axilares. Revista da Associação Médica Brasileira , v. 54, p. 203, 2008.

  • METZE, K . Dichotomization of continuous data A pitfall in prognostic factor studies. Pathology, Research and Practice , v. 204, p. 213-214, 2008.

  • Marinho, Vanessa FZ ; Metze, Konradin ; Sanches, Fernanda SF ; Rocha, Gislene FS ; Gobbi, Helenice . Lymph vascular invasion in invasive mammary carcinomas identified by the endothelial lymphatic marker D2-40 is associated with other indicators of poor prognosis. BMC Cancer (Online) , v. 8, p. 64, 2008.

  • CALONEGO, S ; BARJASCASTRO, M ; METZE, K ; PEREIRA, F ; LORANDMETZE, I . The influence of storage and leukocyte depletion on the antigen densities of FY1, FY2, MNS3 and MNS4 measured by flow cytometry. Transfusion and Apheresis Science , v. 38, p. 101-107, 2008.

  • Delamain, Márcia T. ; Marques, José F.C. ; de Souza, Carmino A. ; Lorand-Metze, Irene ; Metze, Konradin . An algorithm based on peripheral CD34+ cells and hemoglobin concentration provides a better optimization of apheresis than the application of a fixed CD34 threshold. Transfusion (Arlington) , v. 48, p. 1133-1137, 2008.

  • Rocha, Lenaldo B. ; Adam, Randall L. ; Leite, Neucimar J. ; Metze, Konradin ; Rossi, Marcos A. . Shannon's entropy and fractal dimension provide an objective account of bone tissue organization during calvarial bone regeneration. Microscopy Research and Technique , v. 71, p. 619-625, 2008.

  • Kayser K ; Hoshang SA ; Goldmann, Torsten ; METZE, K ; Vollmer E ; Radziszowski D ; Kosjerina, Zdravko ; Mireskandari, Masoud ; Kayser, Gian . Texture- and Object-Related Automated Information Analysis in Histological Still Images of Various Organs. Analytical and Quantitative Cytology and Histology , v. 30, p. 323-335, 2008.

  • Almeida EMP ; Caraca RA ; ADAM, R. L. ; de Souza, Elemir M. ; METZE, K. ; CINTRA, M. L. . Photodamage in feline skin: Clinical and histomorphometric analysis. Veterinary Pathology , v. 45, p. 327-335, 2008.

  • Mello MRB ; METZE, K ; ADAM, R. L. ; Pereira FG ; Magalhaes MG ; Machado CGE ; Lorand-Metze, I . Phenotypic subtypes of acute lymphoblastic leukemia associated with different nuclear chromatin texture. Analytical and Quantitative Cytology and Histology , v. 30, p. 92-98, 2008.

  • Kayser, Klaus ; Görtler, Jürgen ; Metze, Konradin ; Goldmann, Torsten ; Vollmer, Ekkehard ; Mireskandari, Masoud ; Kosjerina, Zdravko ; Kayser, Gian . How to measure image quality in tissue-based diagnosis (diagnostic surgical pathology). Diagnostic pathology , v. 3, p. S11, 2008.

  • Soares AB ; Juliano PB ; Araujo VC ; METZE, K. ; Altemani AM . Angiogenic switch during tumor progression of carcinoma ex-pleomorphic adenoma. Virchows Archiv , v. 451, p. 65-71, 2007.

  • METZE, K ; BEDIN, V ; ADAM, R ; MACEDODESOUZA, E ; CINTRA, M . `Recurrent basal cell carcinomas may represent new primary neoplasias: differences between aggressive and nonaggressive histologic subtypes. Journal of Plastic, Reconstructive and Aesthetic Surgery , v. 60, p. 451-453, 2007.

  • Herreros, F. O. C. ; CINTRA, M. L. ; ADAM, R. L. ; Moraes, A. Machado ; Metze, Konradin . Remodeling of the human dermis after application of salicylate silanol. Archives of Dermatological Research , v. 299, p. 41-45, 2007.

  • LORANDMETZE, I ; RIBEIRO, E ; LIMA, C ; BATISTA, L ; METZE, K . Detection of hematopoietic maturation abnormalities by flow cytometry in myelodysplastic syndromes and its utility for the differential diagnosis with non-clonal disorders. Leukemia Research , v. 31, p. 147-155, 2007.

  • Kayser K ; Kayser G ; METZE, K. . The Concept of Structural Entropy in Tissue-Based Diagnosis. Analytical and Quantitative Cytology and Histology , v. 29, p. 296-308, 2007.

  • Auada MP ; ADAM, R. L. ; LEITE, N. J. ; Puzzi MB ; CINTRA, M. L. ; WILLIAM B, R. ; METZE, K. . Texture analysis of the epidermis based on fast Fourier transformation in Sjogren-Larsson syndrome. Analytical and Quantitative Cytology and Histology , v. 28, p. 219-227, 2006.

  • Rocha, Lenaldo B. ; Adam, Randall L. ; Leite, Neucimar J. ; Metze, Konradin ; Rossi, Marcos A. . Biomineralization of polyanionic collagenelastin matrices during cavarial bone repair. Journal of Biomedical Materials Research. Part A , v. 79A, p. 237-245, 2006.

  • Cavallini, Míriam Elias ; Andreollo, Nelson Adami ; Metze, Konradin ; Araújo, Marina Raquel . Omeprazole and misoprostol for preventing gastric mucosa effects caused by indomethacin and celecoxib in rats. Acta Cirúrgica Brasileira , v. 21, p. 168-176, 2006.

  • ADAM, R. L. ; Silva RC ; Pereira FG ; LEITE, N. J. ; Lorand-Metze I ; METZE, K. . The fractal dimension of nuclear chromatin as a prognostic factor in acute precursor B lymphoblastic leukemia.. Cellular Oncology , v. 28, p. 55-59, 2006.

  • Pereira FG ; METZE, K. ; Costa FP ; Lima CS ; Lorand-Metze I . Phenotypic quantitative features of patients with acute myeloid leukemia.. Neoplasma , v. 53, p. 155-160, 2006.

  • DELAMAIN, M ; METZE, K ; MARQUESJR, J ; REIS, A ; DESOUZA, C ; LORANDMETZE, I . Optimization of CD34+ collection for autologous transplantation using the evolution of peripheral blood cell counts after mobilization with chemotherapy and G-CSF. Transfusion and Apheresis Science , v. 34, p. 33-40, 2006.

  • RIBEIRO, E ; SUDON, S ; SANTIAGO, M ; LIMA, C ; METZE, K ; GIRALT, M ; SAAD, S ; MATOS, A ; LORANDMETZE, I . Maturation-associated immunophenotypic abnormalities in bone marrow B-lymphocytes in myelodysplastic syndromes. Leukemia Research , v. 30, p. 9-16, 2006.

  • Ferreira R C ; de Mattos PS ; ADAM, R. L. ; LEITE, N. J. ; METZE, K. . Application of the Minkowski-Bouligand fractal dimension for the differential diagnosis of thyroid follicular neoplasias. Cellular Oncology , v. 28, p. 331-333, 2006.

  • LEALFILHO, M ; MORANDIN, R ; DEALMEIDA, A ; CAMBIUCCI, E ; BORGES, G ; GONTIJO, J ; METZE, K . Importance of anesthesia for the genesis of neurogenic pulmonary edema in spinal cord injury. Neuroscience Letters , AMSTERDAM, v. 373, p. 165-170, 2005.

  • de Matos, P S ; Ferreira, A P ; de Oliveira Facuri, F ; Assumpcao, L V M ; METZE, K ; Ward, L S . Usefulness of HBME-1, cytokeratin 19 and galectin-3 immunostaining in the diagnosis of thyroid malignancy. Histopathology , v. 47, p. 391-401, 2005.

  • Alborghetti, M. R. ; Correa, M. E. P. ; ADAM, R. L. ; METZE, K. ; Coracin, F. L. ; SOUZA, C. A. ; CINTRA, M. L. . Late effects of chronic graft-vs.-host disease in minor salivary glands. Journal of Oral Pathology and Medicine , v. 34, p. 486-493, 2005.

  • METZE, K. ; Oliveira GB ; Pereira FG ; ADAM, R. L. ; Lorand-Metze I . Spontaneous apoptosis in chronic lymphocytic leukemia is not an independent prognostic factor for stability of disease when compared with combined AgNOR and TTM scores. Cellular Oncology , v. 27, p. 199-201, 2005.

  • Fernandes, Sandra Regina Muchinechi ; Samara, Adil Muhib ; Magalhães, Eduardo Paiva ; Sachetto, Zoraida ; Metze, Konradin . Acute cholecystitis at initial presentation of polyarteritis nodosa. Clinical Rheumatology , v. 24, p. 625-627, 2005.

  • METZE, K. ; Adam, R.L. . Comments on the paper "c-erbB-2 expression and nuclear pleomorphism in canine mammary tumors". Brazilian Journal of Medical and Biological Research , v. 38, p. 141-143, 2005.

  • Leal Filho, Manoel Baldoino ; Morandin, Rosana C. ; Almeida, Amanda R. de ; Cambiucci, Elizabeth C. ; Metze, Konradin ; Borges, Guilherme ; Gontijo, José Antonio Rocha . Hemodynamic parameters and neurogenic pulmonary edema following spinal cord injury: an experimental model. Arquivos de Neuro-Psiquiatria (Impresso) , v. 63, p. 990-996, 2005.

  • Vassallo J ; Pinto GA ; ALVARENGA, M. ; ZEFERINO, L. C. ; CHAGAS, C. A. ; METZE, K. . Comparison of immunoexpression of 2 antibodies for estrogen receptors (1D5 and 6F11) in breast carcinomas using different antigen retrieval and detection methods. Applied Immunohistochemistry , Philadelphia, v. 12, n.2, p. 177-182, 2004.

  • Lorand-Metze, I ; PINHEIRO, M. P. ; PAULA, E. V. ; METZE, K. . Factors influencing survival in myelodysplastic syndromes in a Brazilian population: comparison of FAB and WHO classifications. Leukemia Research , Oxford, v. 28, n.6, p. 587-594, 2004.

  • RIBEIRO, ELISANGELA ; LIMA, CARMEN ; Metze, Konradin ; Lorand-Metze, Irene . Flow Cytometric Analysis of the Expression of Fas/Fasl in Bone Marrow CD34 + Cells in Myelodysplastic Syndromes: Relation to Disease Progression. Leukemia and Lymphoma , Amsterdam, v. 45, p. 309-313, 2004.

  • Vassallo, J. ; Godoy Jr., C.E. ; Godoy, C.E. ; Chagas, C.A. ; METZE, K. ; Trevisan, M.A.S. . Immunoexpression of CD95 in chronic gastritis and gastric mucosa-associated lymphomas. Brazilian Journal of Medical and Biological Research , Riberão Preto, v. 37, p. 1397-1401, 2004.

  • Lorand-Metze, I ; Pereira, Fernanda G. ; Costa FPS ; METZE, K . Proliferation in non-Hodgkin's lymphomas and its prognostic value related to staging parameters. Cellular Oncology , v. 26, p. 63-71, 2004.

  • Vassallo, Jos&amp ; Metze, Konradin ; Traina, Fab&amp ; A. de Souza, C&amp ; Lorand-Metze, Irene . The Prognostic Relevance of Apoptosis-related Proteins in Classical Hodgkin's Lymphomas. Leukemia and Lymphoma , MILTON PARK, ABINGDON OX14 4RN, v. 44, n.2, p. 483-488, 2003.

  • RIBEIRO, E. ; Lima CP ; METZE, K. ; SOUZA, C. A. ; Lorand-Metze I . Changes in hemopoietic precursors after treatment of low-risk myelodysplasia with amifostine. In Vivo (Athens) , Athenas, v. 17, n.2, p. 181-184, 2003.

  • Altemani, A ; Gonzatti A ; METZE, K. . How many paraffin blocks are necessary to detect villitis?. Placenta (Eastbourne) , London, v. 24, n.1, p. 116-117, 2003.

  • Rego, M.F.N. ; Pinheiro, G.S. ; METZE, K. ; Lorand-Metze, I. . Acute leukemias in Piauí: comparison with features observed in other regions of Brazil. brazilian journal of medical and biological research -on line , v. 36, p. 331-337, 2003.

  • HG, Z. ; BEZERRA, R. M. N. ; CARVALHEIRA, J. B. C. ; CARVALHO-FILHO, M. A. ; METZE, K. ; Franchini KG ; Saad MJA . Insulin signalling pathways in aorta and muscle from two animal models of insulin resistance--the obese middle-aged and the spontaneously hypertensive rats. Diabetologia (Berlin) , New York, v. 46, n.4, p. 479-491, 2002.

  • Magalhaes SMM ; Rocha FD ; Vassallo J ; Pinheiro GS ; METZE, K. ; Lorand-Metze I . Bone marrow lymphoid aggregates in myelodysplastic syndromes: incidence, immunomorphological characteristics and correlation with clinical features and survival. Leukemia Research , Oxford, v. 26, n.6, p. 525-530, 2002.

  • Vassallo, J. ; METZE, K. ; Traina F ; SOUZA, C. A. ; Lorand-Metze I . Further remarks on the expression of CD20 in classical Hodgkin's lymphomas.. Haematologica (Roma) , v. 87, p. ELT17, 2002.

  • Oliveira, Gislaine B. ; Pereira, Fernanda G. ; Metze, Konradin ; Lorand-Metze, Irene . Spontaneous apoptosis in chronic lymphocytic leukemia and its relationship to clinical and cell kinetic parameters. Cytometry , New York, v. 46, n.6, p. 329-335, 2001.

  • VALENCA JR, J. T. ; ESCANHOELA, C. A. F. ; METZE, K. . AgNOR pattern and PCNA analysis in fine needle biopsies of liver cell carcinoma. Neoplasma , Bratislava, v. 48, n.5, p. 370-373, 2001.

  • Vassallo J ; METZE, K. ; Traina F ; SOUZA, C. A. ; Lorand-Metze I . Expression of Epstein-Barr virus in classical Hodgkin's lymphomas in Brazilian adult patients. Haematologica (Roma) , Pavia, v. 86, n.11, p. 1227-1228, 2001.

  • Milani G ; Kowaltowski AD ; Saad STO ; METZE, K. ; Vercesi AE . Walker tumor cells express larger amounts of the antiapoptotic protein Bcl-2 and presents higher resistance to toxic concentrations of Ca2+ than the tumor cells K 562. Drug Development Research , New York, v. 52, n.2, p. 408-414, 2001.

  • METZE, K . Clinical value of interphase argyrophilic nucleolar organiser regions in transitional cell bladder tumours. MP. Molecular Pathology , London, v. 54, n.3, p. 200-200, 2001.

  • METZE, K ; CIA, E ; TREVISAN, M . RE: ARGYROPHILIC NUCLEOLAR ORGANIZER REGION IN PROLIFERATING CELL HAS A PREDICTIVE VALUE FOR LOCAL RECURRENCE IN SUPERFICIAL BLADDER TUMOR. The Journal of Urology , Baltimore, v. 163, n.5, p. 1524-1525, 2000.

  • Maffeis GR ; Petrucci O ; Leme CA ; Carandina R ; Leme CA ; Truffa M, ; Vieira R ; Schelini F ; METZE, K. ; Nogueira EA . Cardiac echinococcosis. Circulation (New York, N.Y.) , Baltimore, v. 101, n.11, p. 1352-1354, 2000.

  • Metze, Konradin ; Cia, Erni M. ; Trevisan, Miriam A. . Evaluation of Nucleolar Organizer Regions in Human Bladder Cancers. European Urology , Basel, v. 37, n.1, p. 118-119, 2000.

  • Metze, Konradin ; Lobo, Ana M. ; Lorand-Metze, Irene . Nucleolus organizer regions (AgNORs) and total tumor mass are independent prognostic parameters for treatment-free period in chronic lymphocytic leukemia. International Journal of Cancer (Print) , v. 89, p. 440-443, 2000.

  • METZE, K. ; Chiari, A. C. ; Andrade, F. L. ; Lorand-Metze, I. . Changes in AgNOR configurations during the evolution and treatment of chronic lymphocytic leukemia. Hematology and Cell Therapy (Cessou em 2000) , v. 41, p. 205-210, 2000.

  • METZE, K. ; Lorand-Metze, I . Age Related Decrease of Agnor Activity In Acute And Chronic Lymphocytic Leukemias.. MP. Molecular Pathology (Cessou em 2003) , Londres, v. 52, p. 52-52, 1999.

  • Altemani AM ; Guimaraes P ; METZE, K. . Quantitative analysis of modes of invasion and lymph node metastases in oral squamous cell carcinoma.. Neoplasma (Bratislava) , slovaquia, v. 46, n.5, p. 323-328, 1999.

  • METZE, K. ; Lorand-Metze I . Changes in AgNOR configurations during the evolution and treatment of chronic lymphocytic leukemia.. Hematology and Cell Therapy , Paris, v. 41, n.5, p. 205-210, 1999.

  • METZE, K. ; Lorand-Metze I . Methods for analysing AgNORs.. Journal of Clinical Pathology , London, v. 52, n.7, p. 550-550, 1999.

  • Lorand-Metze, I. ; Meira DG ; Lima CP ; Vassallo J ; METZE, K. . The differential diagnosis between aplastic anemia and hypocellular myelodysplasia in patients with pancytopenia.. Haematologica (Roma) , Pavia, v. 84, n.6, p. 564-565, 1999.

  • METZE, K. . Relationship between histopathological findings and phylogenetic divergence in Trypanosoma cruzi.. TM & IH. Tropical Medicine and International Health , Oxford, v. 4, n.3, p. 238-239, 1999.

  • CIA, E. M. M. ; TREVISAN, M. ; METZE, K. . Argyrophilic nucleolar organizer region (AgNOR) technique: a helpful tool for differential diagnosis in urinary cytology. Cytopathology (Oxford. Print) , v. 10, p. 30-39, 1999.

  • Metze, Konradin ; Trevisan, Miriam A. . The use of epithelial membrane antigen and silver-stained nucleolar organizer regions testing in the differential diagnosis of mesothelioma from benign reactive mesothelioses. Cancer (Print) , v. 85, p. 250-250, 1999.

  • de Oliveira, Cláudia F ; Nathan, Luciana P ; Metze, Konradin ; Moreno, Heitor ; de Luca, Iara M.S ; Sucupira, Mauro ; Zatz, Roberto ; Zappellini, Aldete ; Antunes, Edson ; de Nucci, Gilberto . Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat. European Journal of Pharmacology , v. 373, p. 195-200, 1999.

  • 1999 METZE, K. . Centronuclear myopathy: subgroup characterized by tissue mosaicism. Arquivos de Neuro-Psiquiatria (Impresso) , v. 57, p. 335-336, 1999.

  • Irazusta SP ; Vassallo J ; Magna LA ; METZE, K. ; Trevisan MAS . The Value Of Agnor And Pcna Staining In Endoscopic Biopsies Of Gastric Mucosa .. Pathology, Research and Practice (Print) , Alemanha, v. 194, p. 33-39, 1998.

  • METZE, K. . Methodological Aspects Of Prognostic Factor Studies : Some Caveats .. São Paulo Medical Journal (Impresso) , São Paulo, v. 116, n.4, p. 1787-1787, 1998.

  • METZE, K. . Ängstliche Nivellierung.. Der Spiegel , Hamburg ( Alemanha), v. (1998), n.6, p. 12-12, 1998.

  • Metze, Konradin . Methodological problems of grading tumour regression: responders compared to non-responders. Journal of Cancer Research and Clinical Oncology , v. 124, p. 281-282, 1998.

  • Lorand-Metze, Irene ; Carvalho, Marcelo A. ; Metze, Konradin . Relationship between morphometric analysis of nucleolar organizer regions and cell proliferation in acute leukemias. Cytometry (New York, N.Y.) (Cessou em 2002. Fundiu-se com ISSN 0966-9051 Bioimaging (Bristol. Print)) , v. 32, p. 51-56, 1998.

  • Jorge PA ; Osaki MR ; METZE, K. . Effects Of Hmgcoa Reductase Inhibitors On Endothelial Dysfunction Of Coronary Microvessels In Hypercholesterolemic Rabbits.. Cardiovascular Pathobiology , Estados Unidos, v. 1, p. 167-171, 1997.

  • Moreno H Jr ; Nathan LP ; METZE, K. ; Costa AC ; Antunes E ; HYSLOP, S. ; Zatz R ; De Nucci G . Nitric Oxide Synthase Non-Specific Inhibitors Cause Myocardial Necrosis In The Rat.. Clinical and Experimental Pharmacology & Physiology , Estados Unidos, v. 24, p. 349-352, 1997.

  • Botega NJ, ; METZE, K. ; Marques E ; Cruvinel A ; Moraes ZV ; Costa LA. . Attitudes Of Medical Students To Necropsy.. Journal of Clinical Pathology , Londres, v. 50, n.1, p. 64-66, 1997.

  • METZE, K. . Mesotelioma Maligno de Pleura Com Associação Etiológica A Asbesto. Revista da Associação Médica Brasileira 3 (3), 265 - 272 , 1997. Revista da Associação Médica Brasileira, São,Paulo, v. 43, n.3, p. 265-272, 1997.

  • METZE, K. ; Lorand-Metze, I . Agnor Clusters As A Cell Kinetic Parameter In Chronic Lymphocytic Leukemia .. Journal of Clinical Pathology : Molecular Pathology 49 : 357 - 360, 1997, Londres, v. 49, n.6, p. M357-M360, 1996.

  • Jorge PA ; Ozaki MR ; de Almeida EA ; Credídio Neto L. ; METZE, K. . Effects Of Vitamin e On Endothelium-Dependent Coronary Flow In Hypercholesteroloemic Dogs. Atherosclerosis (Amsterdam) , Estados Unidos, v. 126, p. 43-51, 1996.

  • Moreno H Jr ; METZE, K. ; Bento AC ; Antunes E ; Zatz R ; De Nucci G . Chronic Nitric Oxide Inhibition As A Model Of Ischemic Cardiopathy. Basic Research in Cardiology (Print) , Alemanha, v. 91, p. 248-255, 1996.

  • Gilberti MF ; METZE, K. ; Lorand-Metze, I . Changes Of Nucleolar Organizer Regions In Granulopoietic Precursors During The Course Of Chronic Myeloid Leukemia.. Annals of Hematology (Print) , Alemanha, v. 71, p. 275-279, 1995.

  • Moreno H Jr ; Piovesan Nathan L ; Pereira Costa SK ; METZE, K. ; Antunes E ; Zatz R ; De Nucci G . Enalapril Does Not Prevent The Myocardial Ischemia Caused By The Chronic Inhibition Of Nitric Oxide Synthesis .. European Journal of Pharmacology , v. 287, p. 93-96, 1995.

  • Jorge PA ; Ozaki MR ; METZE, K. . Effect Of Simvastatin And Pravastatin On Endothelium-Dependent Relaxation In Hypercholesterolemic Rabbits.. Experimental and Toxicologic Pathology (Print) , Jena, Alemanha, v. 46, p. 465-469, 1994.

  • ROCHA, A. ; de Meneses AC ; da Silva AM, ; Ferreira MS ; Nishioka SA ; Burgarelli MK ; de Almeida EA ; METZE, K. ; Lopes ER. . Pathology Of Patients With Chagas Disease And Acquired Immunodeficiency Syndrome. .. The American Journal of Tropical Medicine and Hygiene , Estados Unidos, v. 50, n.3, p. 261-268, 1994.

  • METZE, K. ; Andrade LALA . Histology And Immunohistochemistry Of Benign Vaginal Polyps And The Normal Vaginal Subepithelial Layer. Histopathology (Oxford. Print) , v. 22, p. 93-94, 1993.

  • METZE, K. ; Lorand-Metze, I ; Grotto HZW . Pattern Of Nucleolar Organizer Regions In Human Leukemic Cells. Analytical Cellular Pathology (Cessou em 2003. Fundiu-se com ISSN 0884-6812 Analytical and Quantitative Cytology and Histology e ISSN 1570-5870 Cellul , v. 5, p. 203-212, 1993.

  • METZE, K. ; Schnabel R ; Mellin W ; Gullotta F ; Hiddemann W . Heterogeneity Of Centronuclear Myopathy Shown By Flow Cytometry Of Nuclear Dna. Neuropathology and Applied Neurobiology (Print) , v. 19, p. 182-184, 1993.

  • METZE, K. ; JA, M. . Aids And Chagas' Disease. Neurology (Cleveland, Ohio) , v. 43, p. 447-448, 1993.

  • METZE, K. ; Lorand-Metze, I . Interpretation Of The Agnor Pattern In Haematologic Cytology. Acta Haematologica , v. 89, p. 110-112, 1993.

  • METZE, K. . Immunophenotype Of Multinucleated Cells In Giant Cell Lesions. Journal of Clinical Pathology , v. 46, p. 190-191, 1993.

  • METZE, K. ; meves r ; Moreira RS . Seasonal Variation In Rheumatic Heart Disease. International Journal of Cardiology (Print) , v. 38, p. 101-102, 1993.

  • METZE, K. ; Feiden W . Demonstration Of Rabies Virus Antigen At Autopsy. Human Pathology (Print) , v. 24, p. 930-930, 1993.

  • METZE, K. . Tratamento Cirurgico da Bola Fungica Em Lla ( Resposta ), 1993.

  • METZE, K. . Osteoclastic origin of giant cells in giant cell tumors of bone: ultrastructure and cytochemical study of six cases (UP 15:623-629). Ultrastructural Pathology , v. 16, p. 601-602, 1992.

  • METZE, K. . Silver Staining Of Nucleolar Organizer Regions In Prostatic Lesions. Histopathology (Oxford. Print) , v. 21, p. 97-98, 1992.

  • METZE, K. . Abnormal Right Heart Filling After Cardiac Surgery. British Heart Journal , v. 68, p. 250-250, 1992.

  • METZE, K. . Zur Darstellung Des Herzens In Den Werken Von Niels Stensen Und Andreas Vesal. Der Pathologe (Heidelberg) , v. 13, p. 250-251, 1992.

  • METZE, K . Histochemistry of tartrate-resistant acid phosphatase and carbonic anhydrase isoenzyme II in osteoclast-like giant cells in bone tumours.. Virchows Archiv , v. A 420, p. 197-199, 1992.

  • Gilli SCO ; Gilbert MMP ; Frazatto Júnior, C ; METZE, K. ; Ulson CM ; Lorand-Metze, Irene . Tratamento cirúrgico de "bola fúngica" em leucemia linfóide aguda (LLA) / Surgical treatment of fungal bolus in acute lymphoid leukemia. Revista da Associação Médica Brasileira (1992. Impresso) , v. 38, p. 174-176, 1992.

  • Grotto HZW ; Lorand-Metze, I ; METZE, K. . Nucleolar Organizer Regions In Normal Hematopoesis.. Nouvelle revue française d'hématologie , v. 33, p. 1-4, 1991.

  • METZE, K. ; Andrade LALA . Atypical Stromal Giant Cells Of Cervix Uteri - Evidence Of Schwann Cell Origin. Pathology, Research and Practice (Print) , v. 187, p. 1031-1035, 1991.

  • METZE, K. ; Lorand-Metze, I ; de Almeida EA ; de Moraes SL . Reactivatrion Of Chagas' Myocarditis During Therapy Of Hodgkin'S Disease.. Tropical and Geographical Medicine , v. 43, p. 228-230, 1991.

  • Feiden W ; METZE, K. . Zum Immunohistochemischen Nachweis Von Tollwut-Virus Antigen In Herzganglien Des Hundes Am Paraffinschnitt. Tierärztliche Praxis. Ausgabe Kleintiere, Heimtiere , v. 19, p. 247-250, 1991.

  • Jorge PA ; Curti HV ; METZE, K. . A Microcirculacao Coronaria Na Reperfusao Miocardica. O Fenomeno da Nao Reperfusao. Arquivos Brasileiros de Cardiologia (Impresso) , v. 56, p. 471-476, 1991.

  • METZE, K. . A Granulomatose de Wegener - Uma Analise da Descoberta, 1991.

  • METZE, K. ; Feiden W . Rabies Virus Ribonucleoprotein In The Heart.. The New England Journal of Medicine , Boston, Estados Unidos, v. 324, n.181, p. 1814-1815, 1991.

  • METZE, K ; Lorand-Metze, I . AgNOR staining in normal bone marrow cells.. Journal of Clinical Pathology , v. 44, p. 526-526, 1991.

  • Jorge PA ; Curti HH ; METZE, K. . Reserva Circulatoria Coronariana Durante Reperfusao Miocardica Apos 15 Minutos de Isquemia. Arquivos Brasileiros de Cardiologia (Impresso) , v. 54, p. 193-197, 1990.

  • Jorge PA ; METZE, K. ; Nogueira EA ; Credídio Neto L. . Significado das Lesoes Vasculares Intramurais Em Revascularizacao Miocardica. Arquivos Brasileiros de Cardiologia (Impresso) , v. 54, p. 53-55, 1990.

  • Jorge PA ; Curti HV ; METZE, K . A reserva circulatória coronária durante a reperfusäo no infarto do miocárdio. Arquivos Brasileiros de Cardiologia (Impresso) , v. 55, p. 355-360, 1990.

  • Lorand-Metze, Irene ; METZE, K. . A Curabilidade dos Linfomas Nao Hodgkin. Boletim da Sociedade Brasileira de Hematologia e Hemoterapia (Impresso) (Cessou em 1998. Cont. ISSN 1516-8484 Revista Brasileira de Hematologia e Hemo , v. 11, p. 1-3, 1989.

  • METZE, K. . Orcein Positive Granules In Liver Cell Carcinoma. Histopathology (Oxford. Print) , v. 15, p. 204-205, 1989.

  • METZE, K. ; Ciplea AG ; Hettwer H ; Barckhaus RH . Size Dependent Enzyme Activities Of Multinucleated Giant Cells In Bone Tumors. Pathology, Research and Practice (Print) , v. 182, p. 214-221, 1987.

  • Ciplea AG ; METZE, K. ; Grundmann E ; Roessner A ; Hettwer H . Microphotometric Quantitation Of Enzyme Activities In Giant Cell Tumor Of Bone. PATHOLOGY RESEARCH AND PRACTICE , v. 179, p. 412-418, 1985.

  • Roessner A ; METZE, K. ; Heymer B . Aggressive Osteoblastoma. Pathology, Research and Practice (Print) , v. 179, p. 433-438, 1985.

  • METZE, K. ; Brandt G . Copper And Zinc Content Of Liver Heart Skeletal Muscle And Brain In Acute Thioacetamide Intoxication Of Rats. HEPATO-GASTROENTEROLOGY , v. 28, p. 99-101, 1981.

  • METZE, K. . Pathologie Der Hyperosmolaritat. MUNIQUE ( MUNCHEN): DUSTRI VERLAG MUNCHEN -DEISENHOFEN, 1900. 120p .

  • METZE, K. . Artérias, Veias e Linfáticos. In: Geraldo Brasileiro Filho. (Org.). Bogliolo Patologia. 7aed.Rios de Janeiro: Guanabara Koogan, 2006, v. 1, p. 457-487.

  • METZE, K. . Distúrbios da Circulação. In: Geraldo Brasileiro Filho. (Org.). Bogliolo Patologia Geral. 3aed.Rio de Janeiro: Guanabara Koogan, 2004, v. 1, p. 097-129.

  • METZE, K. . Tumores do pulmão. In: Billis A, Vassallo J. (Org.). Patologia Diagnóstica de Tumores. 1ed.Campinas: Impressão Digital do Brasil Gráfica e Editora, 2004, v. , p. 49-66.

  • METZE, K. . Comparative Histologic Study Of Alterations In Rat Skeletal Muscle Due To Carbon Dioxide Laser : Proceedings Of Laser -Tissue Interaction.Spie 3195 ; P13, 1998... Proceedings of Laser -Tissue Interaction.. 1aed.Estados Unidos: SPIE -The International Society for Optical Engineerinmg, 1998, v. 3195, p. -.

  • METZE, K. ; K, M. ; Distúrbios de Circulação. Bogliolo Patologia Geral. 2aed.: Guanabara Koogan, 1998, v. 1, p. -.

  • METZE, K. . Enhancement Of Photodynamic Therapy Due To Hyperbaric Hyperoxia-Dougherty Th ( Ed.) Optical Methods For Tumour Treatment And Detection Vi Spie 2972 : 6p, 1997.... Dougherty Th ( Ed.) Optical methods for tumour treatment and detection : mechanisms and techniques in photodynamic therapy VI SPIE 2972 : 6p. 1ed.Estados Unidos: SPIE, 1997, v. 2972, p. -.

  • METZE, K. . Angiotensin- I - Converting Enzyme. Endokrine Tumoren. 1aed.Stuttgart , Alemanha: G.Fischer Stuttgart, 1997, v. 81, p. -.

  • METZE, K. ; ALMEIDA, E. . Zur Verlaufsform Der Amerikanischen Trypanosomiasis Bei Sekundarem Immundefekt. VERHANDLUNGEN DER DEUTSCHEN GESELLSCHAFT FUR PATHOLOGIE. STUTTGART NEW YORK: G FISCHER, 1992, v. , p. 543-543.

  • METZE, K. . Nucleolus Organisierende Regionen In Interphasenkernen Normalen Und Leukaischen Knochenmarkes. VERHANDLUNGEN DER DEUTSCHEN GESELLSCHAFT FUR PATHOLOGIE. STUTTGART NEW YORK: G FISCHER, 1990, v. , p. 469-469.

  • METZE, K. . Neuritis Cordis Und Myocarditis Bei Tollwut. VERHANDLUNGEN DER DEUTSCHEN GESELLSCAHFT FUR PATHOLOGIE. STUTTGART NEW YORK: G FISCHER, 1990, v. , p. 475-475.

  • METZE, K. . Epitheloides Sarcom Der Vulva. VERHANDLUNGEN DER DEUTSCHEN GESELLSCHAFT FUR PATHOLOGIE. STUTTGART NEW YORK: G FISCHER VERLAG, 1987, v. , p. 551-551.

  • METZE, K. . Eine Sonderform Des Carcinosarkomes Der Lunge. VERHANDLUNGEN DER DEUTSCHEN GESELLSCHAFT FUR PATHOLOGIE. STUTTGART NEW YORK: G FISCHER, 1984, v. , p. 470-470.

  • METZE, K. . Mineralanalytische Und Lichtoptische Befunde Bei Der Glukoseinduzier- Ten Hyperosmolaritat Der Ratte. VERHANDLUNGEN DER DEUTSCHEN GESELLSCAHFT FUR PATHOLOGIE. STUTTGART NEW YORK: G FISCHER, 1981, v. , p. 409-409.

  • METZE, K. . Postmortale Diagnostik Von Elektrolytstorungen Mit Hilfe Der Gesamtgewebsmineralanalyse. CURRENT TOPICS IN NEUROPATHOLOGY. WIEN ( VIENNA): FACULTAS-VERLAG, 1978, v. , p. 15-22.

  • FERRO, D. P. ; VIEIRA-DAMIANI, G. ; ADAM, R. L. ; CESAR, C. L. ; Metze, Konradin ; PERIASAMY, AMMASI ; KÖNIG, KARSTEN ; SO, PETER T. C. . Nonlinear optics for the study of human scar tissue. In: SPIE BiOS, 2012, San Francisco. v. 8226,. p. 82263J.

  • VIEIRA-DAMIANI, GISLAINE ; ADDUR, J. ; FERRO, D. P. ; ADAM, R. L. ; PELEGATI, V. ; THOMÁZ, A. ; CESAR, C. L. ; METZE, K. ; PERIASAMY, AMMASI ; KÖNIG, KARSTEN ; SO, PETER T. C. . Analysis of human aorta using fluorescence lifetime imaging microscopy (FLIM). In: SPIE BiOS, 2012, San Francisco. p. 82260S.

  • VIEIRA-DAMIANI, G. ; FERRO, D. P. ; ADAM, R. L. ; DE THOMAZ, A. A. ; PELEGATI, V. ; CESAR, C. L. ; METZE, K. ; PERIASAMY, AMMASI ; KÖNIG, KARSTEN ; SO, PETER T. C. . <title>Elastic fibers and collagen distribution in human aorta</title>. In: SPIE BiOS, 2011, San Francisco. p. 79030B.

  • THOMAZ, A. A. ; W. M. Faustino ; A. Fontes ; H. P. Fernandes ; M. L. Barjas-Castro ; METZE, K. ; S. Giorgio ; L. C. Barbosa ; C.L.Cesar . ?Optical tweezers and multiphoton microscopies integrated photonic tool for mechanical and biochemical cell processes studies?. In: 2. Optics and Photonics 2007 da The International Society for Optical Engineering ? SPIE, 2007, San Diego, California, EUA. 2. Optics and Photonics 2007 da The International Society for Optical Engineering ? SPIE, 2007.

  • METZE, K. ; ADAM, R. L. ; LEITE, N. J. . Cell Music: The Sonification of Digitalized Fast-Fourier. In: IX Brazilian Symposium on Computer Music, 2003, Campinas. IX Brazilian Symposium on Computer Music. Campinas: Sociedade Brasileira de Computação, 2003. v. 1. p. 1-10.

  • METZE, K. . Photodynamic Therapy In Hyperbaric Hyperoxia- Proceedings Of The International Joint Meeting On Hyperbaric And 73 - 79 ..1996... In: the International Joint Meeting on Hyperbaric and Underwater Medicine, 1996. ( Marroni A, Oriani G, Wattel F, Eds. ) Proceedings of the International Joint Meeting on Hyperbaric and Underwater Medicine.... Bologna, Italia. v. 1. p. 73-79.

  • METZE, K. ; CABRAL, D. . Terapia Fotodinámica Em Hiperoxigenação Hiperbárica.Anais Volume I ,Páginas 327 e 328 , Forum Nacional de Ciência e Tecnologia Em Saude.... In: Forum Nacional de Ciência e Tecnologia em Saude, XV congresso Brasileiro de Engenharia Biomédica, VI Congresso Brasileiro de Físicos em Medicina, Campos do Jordão, 1996, 1996. Anais Volume I ,páginas 327 e 328 , Forum Nacional de Ciência e Tecnologia em Saude.. Campos do Jordão. v. 1. p. 327-328.

  • METZE, K. . Chronic Nitric Oxide Blockade Causes Cardiac Ischemia But Not Cardiac Hypertrophy. In: FORUM NACIONAL DE CIENCIA E TECNOLOGIA EM SAUDE/VI CONGRESSO BRASIL DE FISCIOS EM MEDICINA, 1904. CAMPOS DO JORDAO, SP. p. 0-0.

  • Lorand-Metze I ; Califani SMV ; RIBEIRO, E. ; Lima CSP ; Saad STO ; METZE, K. . The impact of phenotypic abnormalities on survival of myelodysplastic syndromes. In: 9th International Symposium on Myelodysplastic Syndromes, 2007, Firence , Italia. Leukemia Research. OXFORD OX5 1GB, ENGLAND: PERGAMON-ELSEVIER SCIENCE LTD, 2007. v. 31. p. 131-131.

  • Lorand-Metze I ; de Mello M RB ; ADAM, R. L. ; LEITE, N. J. ; Mello RAM ; Costa EF ; METZE, K. . Nuclear morphometric variables as prognostic factors in acute lymphoblastic leukemia. In: European Society of Hematology, 2007, Wien, Austria. Haematologica. PAVIA ITALIA: FERRATA STORTI FOUNDATION, 2007. v. 92. p. 519-519.

  • METZE, K. ; de Mello M RB ; ADAM, R. L. ; LEITE, N. J. ; Lorand-Metze I . ENTROPY OF THE CHROMATIN TEXTURE IN ROUTINELY STAINED CYTOLOGY IS A PROGNOSTIC FACTOR IN ACUTE LYMPHOBLASTIC LEUKEMIA. In: 21st European Congress of Pathology, 2007, Istanbul. Virchows Archiv. Berlin: Springer, 2007. v. 451. p. 114-114.

  • VIGORITO, A. ; METZE, K. . The Value Of Minor Salivary Gland Biopsies As An Indicator Of Poor Prognosis In Patients With Chronic Graft- Versus- Host Disease.. In: Congress of the International Academy of Pathology , Nice, 1998, 1998. Archives d'Anatomie et de Cytologie Pathologiques. Nice, França. v. 46. p. 462-462.

  • METZE, K. . Developmental Agnor Changes In Rat Cardiomyocytes.. In: 6th International workshop on Applications of AgNORs in Pathology, 1998. European Journal of Histochemistry. Bologna, Italia, 1998. v. 42. p. 22-22.

  • METZE, K. . Morphometric Agnor Parameters And Their Relationship To Cell Proliferation In Acute Leukemias.. In: 6th International Workshop on Applications of AgNORs in Pathology, 1998. European Journal of Histochemistry. Bologna, Italia. v. 42. p. 19-19.

  • METZE, K. . Nucleolar Organizer Regions As A Proliferation Marker In Chronic Lymphoid Leukemia.. In: 6th International Workshop on Applications of AgNORs in Pathology, 1998. European Journal of Histochemistry. Bologna, Italia. v. 42. p. 19-19.

  • METZE, K. . Criteria For The Differential Diagnosis Between Aplastic Anemia And Hypocellular Myelodysplasia Leukemia Research 21 : S9, 1997... In: 4th International Symposium on Myelodysplastic Syndromes, 1997. Leukemia Research 21 : S9, 1997... Barcelona. v. 21. p. S9-S9.

  • METZE, K. . Photodynamic Therapy In Hyperbaric Hyperoxia.. In: Congress of the European Society of Pathology, Maastricht, 1997, 1997. Pathology Research and Practice 193 : 420, 1997. Stuttgart, Alemanha. v. 193. p. 420-420.

  • METZE, K. . The Importance Of Different Agnor-Parameters For The Evaluation Of Cell Kinetics In Acute Leukemias.. In: Congress of the European Society of PAthology, Maastricht, 1997, 1997. Pathology Research and Practice. Statuttgart, Alemanha. v. 193. p. 421-421.

  • METZE, K. . The Value Of Agnor Staining In Urological Cytologypathology International, 46, Supplement 1, No 171, 1996. In: XXI International Congress of the International Academy of Pathology and 12th World Congress of Academic and Environmental Pathology, 1996. Pathology International, 46, Supplement 1, No 171, 1996.... Budapest. v. 46sup1. p. No171-No171.

  • METZE, K. . Pcna - And Agnor Staining In Gastric Mucosal Lesions. In: XXI International Congress of the International Academy of Pathology and 12th World Congress of Academic and Environmental Pathology, 1996. Pathology International, 46, Supplement 1, No 297, 1996.. Budapest, Hungria. v. 46su1. p. No297-No297.

  • METZE, K. . The Pattern Of Nucleolar Organizer Regions As A Prognostic Parameter In Chronic Lymphoid Leukemia.Pathology International, 46, Supplement 1, No 484, 1996.... In: XXI International Congress of the International Academy of Pathology and 12th World Congress of Academic and Environmental Pathology, 1996. Pathology International, 46, Supplement 1, No 484, 1996.. Budapest, Hungria. v. 46. p. 484-484.

  • METZE, K. . The Prognostic Value Of Bone Marrow Features In Chronic Myelogenous Leukemia.Pathology International, 46, Supplement 1, No 485, 1996.... In: XXI International Congress of the International Academy of Pathology, 1996. Pathology International, 46, Supplement 1, No 485, 1996.. Budapest, Hungria. v. 46. p. 485-485.

  • METZE, K. . Attitudes Of Medical Students Towards The Autopsy. In: XXI International Congress of the International Academy of Pathology and 12th World Congress of Academic and Environmental Pathology, 1996. Pathology International, 46, Supplement 1, No 588 1996.. Budapest, Hungria. v. 46. p. 588-588.

  • METZE, K. . Study Of Contractile Response Of The Left Atrium To Adrenergic Stimulation In Young Adults And Aged Rats... In: APS Intersociety Meeting , october 16 - 19, 1996, 1996. The Physiologist,. Vancouver,BC, Canada. v. 39. p. 17.8-17.8.

  • METZE, K. . Histology Of The Labial Salivary Glands As A Prognostic Factor After Allogeneic Bone Marrow Transplantation.Pathology , Research And Practice, 193, 414, 1997.... In: Congress of European Society of Pathology, Maastricht, 1997, 1994. Pathology , Research and Practice, 193, 414, 1997. v. 193. p. 414-414.

  • METZE, K. . Nucleolar Organizer Regions As A Parameter Of Disease Activity In Cll. In: SPIE, 1909. SAN JOSE, CA ESTADOS UNIDOS. p. 0-0.

  • METZE, K. . Inhibition Of Nitric Oxide - A New Model Of Ischemic Cardiopathy. In: VII ENCONTRO NACIONAL DE VIROLOGIA DA SOCIEDADE BRASILEIRA DE VIROLOGIA, 1909. SAO LOURENCO-MG. p. 0-0.

  • METZE, K. . The Inflammatory Reaction In Placental Chagas' Disease. In: XXI INTERNATIONAL CONGRESS OF THE INTERNATIONAL ACADEMY OF PATHOLOGY, 1909. BUDAPEST, HUNGRIA. p. 0-0.

  • METZE, K. . Rabia : Muerte En Perros Sin Sintomas de La Dolencia. In: XXI INTERNATIONAL CONGRESS OF THE INTERNATIONAL ACADEMY OF PATHOLOGY, 1908. BUDAPEST, HUNGRIA. p. 0-0.

  • METZE, K. . Recrudescence Of T Cruzi Infection In Cancer Patients Treated With Chemotherapy. In: XXI INTERNATIONAL CONGRESS OF THE INTERNATIONAL ACADEMY OF PATHOLOGY, 1908. BUDAPEST, HUNGRAI. p. 0-0.

  • METZE, K. . Enalapril Does Not Prevent The Myocardial Ischemia In The Cardiopathy Induced By Chronic Inhibition Of Nitric Oxide Synthesis. In: XXI INTERNATIONAL CONGRESS OF THE INTERNATIONAL ACADEMY OF PATHOLOGY, 1908. BUDAPEST, HUNGRIA. p. 0-0.

  • METZE, K. . Enalalpril Prevents The Development Of Cardiac Hypertrophy In The Arterial Hypertension Induced By Chronic Inhibition Of The Nitric Oxide Synthesis. In: XXI INTERNATIONAL CONGRESS OF THE INTERNATIONAL ACADEMY OF PATHOLOGY, 1908. BUDAPEST, HUNGRIA. p. 0-0.

  • METZE, K. . Tecnica Agnor- Um Auxilio No Diagnostico Diferencial Em Citologia Urinaria. In: ASP INTERSOCIETY MEETING, 1908. VANCOUVER BC, CANADA. p. 0-0.

  • METZE, K. . Regioes Organizadoras de Nucelolos Como Parametro Prognostico Em Llc. In: NA INTERNET:HTTP://WWW.IMEDICA.COM.BR/ARTIGOS/CARDIO1.HTML INTERFACE MEDICO-ARTIGOS, 1908. INTERNET. p. 0-0.

  • METZE, K. . Hipoplasia da Aorta Associada Com Morte Subita. In: XIX ENCONTRO NACIONAL DE FISICA CONDENSADA, 1908. AGUAS DE LINDOIA, SP. p. 0-0.

  • METZE, K. . Comparacao Cito-Histologica de Material Vesical. In: SECOND WORLD CONGRESS ON LABORATORY ANIMAL SCIENCES, 1908. RIO DE JANEIRO RJ. p. 0-0.

  • METZE, K. . Inibicao da Sintese de Oxido Nitrico - Um Novo Modelo de Cardiopatia. In: SECOND WORLD CONGRESS ON LABORATORY ANIMAL SCIENCES, 1908. RIO DE JANEIRO, RJ. p. 0-0.

  • ADAM, R. L. ; RIBEIRO, E. ; METZE, K. ; LEITE, N. J. ; Lorand-Metze I . Morphometric and granulometric features of erythroblasts as a diagnostic tool of hematologic diseases. Cytometry , HOBOKEN, NJ 07030 USA, v. 59A, n.1, p. 46-46, 2004.

  • Lorand-Metze I ; RIBEIRO, E. ; METZE, K. . Detection of hematopoietic maturation abnormalities by flow cytometry and its utility for the diagnosis of myelodysplastic syndromes. Cytometry , HOBOKEN, NJ 07030 USA, v. 59A, n.1, p. 59-59, 2004.

  • ADAM, R. L. ; LEITE, N. J. ; CARVALHO, R. B. ; SILVA, P. V. V. T. ; METZE, K. . Granulometric residues as a diagnostic tool in cytology. Cytometry , HOBOKEN, NJ 07030 USA, v. 59A, n.1, p. 63-63, 2004.

  • METZE, K. ; ADAM, R. L. ; SILVA, P. V. V. T. ; CARVALHO, R. B. ; LEITE, N. J. . Analysis of chromatin texture by Pinkus' approximate entropy. Cytometry , HOBOKEN, NJ 07030 USA, v. 59A, n.1, p. 63-63, 2004.

  • ADAM, R. L. ; CORSINI, T. C. G. ; SILVA, P. V. V. T. ; CINTRA, M. L. ; LEITE, N. J. ; METZE, K. . Fractal dimensions applied to thick contour detection and residues - Comparison of keloids and hypertrophic scars. Cytometry , HOBOKEN, NJ 07030 USA, v. 59A, n.1, p. 63-64, 2004.

  • METZE, K. ; ADAM, R. L. ; LEITE, N. J. . The sonification of cytologic images. Cytometry , HOBOKEN, NJ 07030 USA, v. 59A, n.1, p. 85-85, 2004.

  • METZE, K. ; Meirelles LA ; Hessel G ; ESCANHOELA, C. A. F. . Precocity of liver disease in cystic fibrosis (CF).. Hepatology (Baltimore, Md.) , Philadelphia, v. 34, n.4, p. 1325-1325, 2001.

  • Milani G ; Kowaltowski AD ; Saad STO ; METZE, K. ; Vercesi AE . Characteristics of mitochondrial Ca2+ uptake is two tumor cell lines with different Bcl-2 expression. Biophysical Journal , Bethesda, v. 78, n.1, p. 824-824, 2000.

  • METZE, K. ; Milani G ; Kowaltowski AD ; Saad STO ; Vercesi AE . Characteristics of mitochondrial Ca2+ uptake is two tumor cell lines with different Bcl-2 expression. Biophysical Journal , BETHESDA, MD 20814-3998, v. 78, n.1, p. 140A-140A, 2000.

  • METZE, K. ; Fernanda Borges da Silva ; LORAND-METZE, I. . Lowering the p-value from 0.05 to 0.005 conflicts with the 3R rules - an advocacy for 1 alternatives to hypothesis testing with the p-value approach 2 3. ALTEX-Alternatives to Animal Experimentation , 2018.

Outras produções

ADAM, R. L. ; LEITE, N. J. ; METZE, K. . Spectral. 2002.

Prêmios

1995

PRIMEIRO LUGAR : TEMAS LIVRES XX CONGRESSO BRASILEIRO DE PATOLOGIA BELO HORIZONTE 01.08.1995 ( NA QUALIDADE DE PRIMEIRO AUTOR ), SOCIEDADE BRASILEIRA DE PATOLOGIA/SBP*.

1994

SEGUNDO LUGAR : TEMAS LIVRES XVI CONGRESSO DA SOCIEDADE DE CARDIOLOGIA DO ESTADO DE SAO PAULO ( NA QUALIDADE DE CO-AUTOR), SOCIEDADE DE CARDIOLOGIA DO ESTADO DE SAO PAULO.

Histórico profissional

Endereço profissional

  • Universidade Estadual de Campinas, Faculdade de Ciências Médicas da UNICAMP. , CP 6111, Barão Geraldo, 13081-970 - Campinas, SP - Brasil - Caixa-postal: 6111, Telefone: (019) 32893897, Fax: (019) 32893897

Experiência profissional

1988 - Atual

Universidade Estadual de Campinas

Vínculo: Servidor Público, Enquadramento Funcional: Prof pleno Pós Fisiopatologia e Ciên. Médic., Carga horária: 40, Regime: Dedicação exclusiva.

Atividades

  • Direção e administração, Faculdade de Ciências Médicas da UNICAMP, Departamento de Anatomia Patológica da FCM/UNICAMP.,Cargo ou função, COORDENADOR POS-GRADUACAO EM ANATOMIA PATOLOGICA // COORDENADOR DO LABORATORIO DE ANATOMIA PATOLOGICA EXPE // RIMENTAL NO NUCLEO DE MEDICINA E CIRURGIA EXPERIMENTAL // DA UNICAMP.

  • Pesquisa e desenvolvimento, Faculdade de Ciências Médicas da UNICAMP, Departamento de Anatomia Patológica da FCM/UNICAMP.,Linhas de pesquisa

  • Ensino,,Disciplinas ministradas, 1. SEMINARIOS EM PATOLOGIA GERAL ( 2.SEM 94,1.SEM 96 ) // 2. METODOLOGIA CIENTIFICA (1.SEM 95 E 1. SEM 96 ) // 3. CARACTERISTICAS DAS NEOPLASIAS MALIGNAS ( 2.SEM 94)

  • Ensino,,Disciplinas ministradas, 1. PATOLOGICA DAS NEOPLASIAS NA DISCIPLINA &quot; PATOLOGIA // GERAL&quot; ( 1. SEM 95, 1. SEM 96 ) // 2. PATOLOGIA DO SISTEMA CARDIOVASCULAR NA DISCIPLINA // &quot; PATOLOGICA ESPECIAL&quot; ( 1. SEM 95, 1.SEM 96

  • Estágios , Faculdade de Ciências Médicas da UNICAMP, Departamento de Anatomia Patológica da FCM/UNICAMP.,Estágio realizado, 1.EXAMES DE PATOLOGIA CIRURGICA, AUTOPSIA INCL EXAMES // ULTRAESTRUTURAIS // 2.CONSULTORIAS COM " REFEREE" PARA REVISTAS NACIONAIS // INTERNACIONAIS E ORGAOS DE FOMENTO A PESQUISA.

Propriedade Intelectual

Patentes (1)

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