Natércia Aurora Almeida Teixeira

Idiomas

Áreas de atuação

Produções bibliográficas

• AUGUSTO, TIAGO VIEIRA ; CORREIA-DA-SILVA, GEORGINA ; RODRIGUES, CECÍLIA M P ; TEIXEIRA, NATÉRCIA ; AMARAL, CRISTINA . Acquired resistance to aromatase inhibitors: where we stand!. ENDOCRINE-RELATED CANCER , v. 25, p. R283-R301, 2018.

• FONSECA, B. M. ; CORREIA-DA-SILVA, G. ; TEIXEIRA, N. A. . Cannabinoid-induced cell death in endometrial cancer cells: involvement of TRPV1 receptors in apoptosis. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY , v. 74, p. 261-272, 2018.

• SÁ, SUSANA I. ; TEIXEIRA, NATÉRCIA ; FONSECA, BRUNO M. . Effects of tamoxifen on neuronal morphology, connectivity and biochemistry of hypothalamic ventromedial neurons: Impact on the modulators of sexual behavior. NEUROBIOLOGY OF DISEASE , v. 109, p. 33-43, 2018.

• AMARAL, CRISTINA ; AUGUSTO, TIAGO VIEIRA ; TAVARES-DA-SILVA, ELISIÁRIO ; ROLEIRA, FERNANDA M.F. ; CORREIA-DA-SILVA, GEORGINA ; TEIXEIRA, NATÉRCIA . Hormone-dependent breast cancer: Targeting autophagy and PI3K overcomes Exemestane-acquired resistance. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY , v. 183, p. 51-61, 2018.

• ALMADA, M. ; FONSECA, B. M. ; AMARAL, C. ; DINIZ-DA-COSTA, M. ; CORREIA-DA-SILVA, G. ; TEIXEIRA, N. . Anandamide oxidative metabolism-induced endoplasmic reticulum stress and apoptosis. APOPTOSIS , v. 22, p. 816-826, 2017.

• AMARAL, CRISTINA ; VARELA, CARLA L. ; MAURÍCIO, JOÃO ; SOBRAL, ANA FILIPA ; COSTA, SAUL C. ; ROLEIRA, FERNANDA M.F. ; TAVARES-DA-SILVA, ELISIÁRIO J. ; CORREIA-DA-SILVA, GEORGINA ; TEIXEIRA, NATÉRCIA . Anti-tumor efficacy of new 7α-substituted androstanes as aromatase inhibitors in hormone-sensitive and resistant breast cancer cells. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY , v. 171, p. 218-228, 2017.

• MAIA, J. ; ALMADA, M. ; SILVA, A. ; CORREIA-DA-SILVA, G. ; TEIXEIRA, N. ; SÁ, S.I. ; FONSECA, B.M. . The endocannabinoid system expression in the female reproductive tract is modulated by estrogen. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY , v. 174, p. 40-47, 2017.

• ALMADA, MARTA ; COSTA, LIA ; FONSECA, BRUNO MIGUEL ; AMARAL, CRISTINA ; TEIXEIRA, NATÉRCIA ; CORREIA-DA-SILVA, GEORGINA . The synthetic cannabinoid WIN-55,212 induced-apoptosis in cytotrophoblasts cells by a mechanism dependent on CB1 receptor. TOXICOLOGY , v. 385, p. 67-73, 2017.

• AMARAL, CRISTINA ; TOLOI, MARIA REGINA T. ; VASCONCELOS, LUIS DANIEL ; FONSECA, MARIA JOSÉ V. ; CORREIA-DA-SILVA, GEORGINA ; TEIXEIRA, NATÉRCIA . The role of soybean extracts and isoflavones in hormone-dependent breast cancer: aromatase activity and biological effects. Food & Function , v. I, p. XXX-XXXX, 2017.

• COSTA, LIA ; AMARAL, CRISTINA ; TEIXEIRA, NATÉRCIA ; CORREIA-DA-SILVA, GEORGINA ; FONSECA, BRUNO M. . Cannabinoid-induced autophagy: Protective or death role?. PROSTAGLANDINS & OTHER LIPID MEDIATORS , v. 122, p. 54-63, 2016.

• VARELA, CARLA L. ; AMARAL, CRISTINA ; CORREIA-DA-SILVA, GEORGINA ; COSTA, SAUL C. ; CARVALHO, RUI A. ; COSTA, GIOSUÈ ; ALCARO, STEFANO ; TEIXEIRA, NATÉRCIA A.A. ; TAVARES-DA-SILVA, ELISIÁRIO J. ; ROLEIRA, FERNANDA M.F. . Exploring new chemical functionalities to improve aromatase inhibition of steroids. BIOORGANIC & MEDICINAL CHEMISTRY , v. 24, p. 2823-2831, 2016.

• SÁ, SUSANA I. ; FONSECA, BRUNO M. ; TEIXEIRA, NATÉRCIA ; MADEIRA, M. DULCE . Induction and subcellular redistribution of progesterone receptor A and B by tamoxifen in the hypothalamic ventromedial neurons of young adult female Wistar rats. MOLECULAR AND CELLULAR ENDOCRINOLOGY , v. 420, p. 1-10, 2016.

• COSTA, M.A. ; FONSECA, B.M. ; MENDES, A. ; BRAGA, J. ; TEIXEIRA, N.A. ; CORREIA-DA-SILVA, G. . The endocannabinoid 2-arachidonoylglycerol dysregulates the synthesis of proteins by the human syncytiotrophoblast. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS , v. 1861, p. 205-212, 2016.

• ALMADA, M ; AMARAL, C ; DINIZ-DA-COSTA, M ; CORREIA-DA-SILVA, G ; TEIXEIRA, N A ; FONSECA, B M . The endocannabinoid anandamide impairs in vitro decidualization of human cells. REPRODUCTION , v. 152, p. 351-361, 2016.

• SOBRAL, ANA FILIPA ; AMARAL, CRISTINA ; CORREIA-DA-SILVA, GEORGINA ; TEIXEIRA, NATÉRCIA . Unravelling exemestane: From biology to clinical prospects. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY , v. 163, p. 1-11, 2016.

• COSTA, M.A. ; KEATING, E. ; FONSECA, B.M. ; TEIXEIRA, N.A. ; CORREIA-DA-SILVA, G. . 2-Arachidonoylglycerol impairs human cytotrophoblast cells syncytialization: Influence of endocannabinoid signalling in placental development. MOLECULAR AND CELLULAR ENDOCRINOLOGY , v. 399, p. 386-394, 2015.

• ALMADA, M. ; PISCITELLI, F. ; FONSECA, B.M. ; DI MARZO, V. ; CORREIA-DA-SILVA, G. ; TEIXEIRA, N. . Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS , v. 1851, p. 1473-1481, 2015.

• FONSECA, B.M. ; CORREIA-DA-SILVA, G. ; TEIXEIRA, N.A. . Anandamide restricts uterine stromal differentiation and is critical for complete decidualization. MOLECULAR AND CELLULAR ENDOCRINOLOGY , v. 411, p. 167-176, 2015.

• SÁ, SUSANA I. ; FONSECA, BRUNO M. ; TEIXEIRA, NATÉRCIA ; MADEIRA, M. DULCE . Estrogen receptors α and β have different roles in the induction and trafficking of progesterone receptors in hypothalamic ventromedial neurons. FEBS Journal , v. 282, p. 1126-1136, 2015.

• AMARAL, CRISTINA ; LOPES, ANDREIA ; VARELA, CARLA L. ; DA SILVA, ELISIÁRIO TAVARES ; ROLEIRA, FERNANDA M.F. ; CORREIA-DA-SILVA, GEORGINA ; TEIXEIRA, NATÉRCIA . Exemestane metabolites suppress growth of estrogen receptor-positive breast cancer cells by inducing apoptosis and autophagy: A comparative study with Exemestane. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY , v. 69, p. 183-195, 2015.

• ALMADA, MARTA ; DOMINGUES, M. ROSÁRIO ; DÓRIA, M. LUÍSA ; FONSECA, BRUNO M. ; TEIXEIRA, NATÉRCIA A. ; CORREIA-DA-SILVA, GEORGINA . Lipidomic approach towards deciphering anandamide effects in rat decidual cell. JOURNAL OF CELLULAR PHYSIOLOGY , v. 230, p. 1549-1557, 2015.

• COSTA, M. A. ; FONSECA, B. M. ; MENDES, A. ; BRAGA, J. ; TEIXEIRA, N. A. ; CORREIA DA SILVA, GEORGINA . The endocannabinoid anandamide affects the synthesis of human syncytiotrophoblast-related proteins. CELL AND TISSUE RESEARCH , v. 362, p. 441-446, 2015.

• COSTA, M.A. ; FONSECA, B.M. ; TEIXEIRA, N.A. ; CORREIA-DA-SILVA, G. . The endocannabinoid anandamide induces apoptosis in cytotrophoblast cells: Involvement of both mitochondrial and death receptor pathways. PLACENTA , v. 36, p. 69-76, 2015.

• COSTA, M.A. ; FONSECA, B.M. ; MARQUES, F. ; TEIXEIRA, N.A. ; CORREIA-DA-SILVA, G. . The psychoactive compound of Cannabis sativa, -9-tetrahydrocannabinol (THC) inhibits the human trophoblast cell turnover. TOXICOLOGY , v. 334, p. 94-103, 2015.

• PEREIRA, DAVID M. ; VALENTÃO, PATRÍCIA ; CORREIA-DA-SILVA, GEORGINA ; TEIXEIRA, NATÉRCIA ; ANDRADE, PAULA B. . Translating endoplasmic reticulum biology into the clinic: a role for ER-targeted natural products?. NATURAL PRODUCT REPORTS , v. 32, p. 705-722, 2015.

• COSTA, M A ; FONSECA, B M ; KEATING, E ; TEIXEIRA, N A ; CORREIA-DA-SILVA, G . 2-Arachidonoylglycerol effects in cytotrophoblasts: metabolic enzymes expression and apoptosis in BeWo cells. REPRODUCTION , v. 147, p. 301-311, 2014.

• FONSECA, B.M. ; BATTISTA, N. ; CORREIA-DA-SILVA, G. ; RAPINO, C. ; MACCARRONE, M. ; TEIXEIRA, N.A. . Activity of anandamide (AEA) metabolic enzymes in rat placental bed. REPRODUCTIVE TOXICOLOGY , v. 49, p. 74-77, 2014.

• PEREIRA, DAVID M. ; CORREIA-DA-SILVA, GEORGINA ; VALENTÃO, PATRÍCIA ; TEIXEIRA, NATÉRCIA ; ANDRADE, PAULA B. . Anti-Inflammatory Effect of Unsaturated Fatty Acids and Ergosta-7,22-dien-3-ol from Marthasterias glacialis: Prevention of CHOP-Mediated ER-Stress and NF-κB Activation. PLoS One , v. 9, p. e88341, 2014.

• VARELA, CARLA L. ; AMARAL, CRISTINA ; TAVARES DA SILVA, ELISIÁRIO ; LOPES, ANDREIA ; CORREIA-DA-SILVA, GEORGINA ; CARVALHO, RUI A. ; COSTA, SAUL C.P. ; ROLEIRA, FERNANDA M.F. ; TEIXEIRA, NATÉRCIA . Exemestane metabolites: Synthesis, stereochemical elucidation, biochemical activity and anti-proliferative effects in a hormone-dependent breast cancer cell line. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , v. 87, p. 336-345, 2014.

• PEREIRA, DAVID ; CORREIA-DA-SILVA, GEORGINA ; VALENTAO, PATRICIA ; TEIXEIRA, NATERCIA ; ANDRADE, PAULA . GC-MS Lipidomic Profiling of the Echinoderm Marthasterias glacialis and Screening for Activity Against Human Cancer and Non-Cancer Cell Lines. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING , v. 17, p. 450-457, 2014.

• VARELA, CARLA L. ; ROLEIRA, FERNANDA M. F. ; COSTA, SAUL C. P. ; PINTO, ALEXANDRA S. C. T. ; MARTINS, ANA I. O. S. ; CARVALHO, RUI A. ; TEIXEIRA, NATÉRCIA A. ; CORREIA-DA-SILVA, GEORGINA ; TAVARES-DA-SILVA, ELISIÁRIO . Insights into the Synthesis of Steroidal -Ring Olefins. HELVETICA CHIMICA ACTA , v. 97, p. 39-46, 2014.

• PEREIRA, DAVID ; CORREIA-DA-SILVA, GEORGINA ; VALENTÃO, PATRÍCIA ; TEIXEIRA, NATÉRCIA ; ANDRADE, PAULA . Palmitic Acid and Ergosta-7,22-dien-3-ol Contribute to the Apoptotic Effect and Cell Cycle Arrest of an Extract from Marthasterias glacialis L. in Neuroblastoma Cells. Marine Drugs , v. 12, p. 54-68, 2014.

• FONSECA, B. M. ; ALMADA, M. ; COSTA, M. A. ; TEIXEIRA, N. A. ; CORREIA-DA-SILVA, G. . Rat spontaneous foetal resorption: altered α2-macroglobulin levels and uNK cell number. HISTOCHEMISTRY AND CELL BIOLOGY , v. 142, p. 693-701, 2014.

• COSTA, M.A. ; FONSECA, B.M. ; KEATING, E. ; TEIXEIRA, N.A. ; CORREIA-DA-SILVA, G. . Transient receptor potential vanilloid 1 is expressed in human cytotrophoblasts: Induction of cell apoptosis and impairment of syncytialization. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY , v. 57, p. 177-185, 2014.

• PEREIRA, DAVID M. ; VALENTÃO, PATRÍCIA ; TEIXEIRA, NATÉRCIA ; ANDRADE, PAULA B. . Amino acids, fatty acids and sterols profile of some marine organisms from Portuguese waters. FOOD CHEMISTRY , v. 141, p. 2412-2417, 2013.

• FONSECA, B. M. ; TEIXEIRA, N. A. ; CORREIA-DA-SILVA, G. . Cannabinoids as Modulators of Cell Death: Clinical Applications and Future Directions. Reviews of Physiology, Biochemistry and Pharmacology. 2ed.: Springer International Publishing, 2017, v. , p. 63-88.

Projetos de pesquisa

• 2016 - 2019

  The endocannabinoids as modulators of cell death and differentiation: A unified hypothesis of how cannabinoids affect placental development, Descrição: ---. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.

• 2015 - 2018

  New technologies for three health challenges of modern societies: diabetes, drug abuse and kideney diseases., Descrição: ---. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.

• 2012 - 2015

  New enzyme inhibitors for breast and prostate cancers: insights to overcome bone loss and endocrine resistance? - (PTDC/QUI-BIQ/120319/2010), Descrição: ----. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.

• 2011 - 2014

  Cross-talk between chronic renal failure, inflammation and erythropoiesis in resistance to recombinant human erythropoietin therapy, Descrição: ---. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.

• 2003 - 2006

  Biomolecular and ultrasonografic characteristics of the endometrium of patients with endometriosis, Descrição: ---. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.

• 2003 - 2004

  Uterine apoptosis: its role in the development of the fetoplacental unit, Descrição: ---. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.

• 1999 - 2002

  Evaluation, as a diagnostic and activity marker of disease, of the reactivity of auto-antibodies of patients with Systemic lupus erithomatosus with the human nuclear auto-antigen MCP1, Descrição: ---. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.

• 1992 - 1993

  Function of decidualization associated-protein, Descrição: ---. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.

• 1987 - 1991

  Study of the function of Decidualization-associated protein (DAP). Synthesis of high molecular weight proteins by human decidua., Descrição: ---. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Natércia Aurora Almeida Teixeira - Coordenador.