Arthur Andrade Nery

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Produções bibliográficas

• NERY, Arthur Andrade ; Resende, Rodrigo R. ; Martins, Antonio H. ; Trujillo, Cleber A. ; Eterovic, Vesna A. ; Ulrich, Henning . Alpha7 Nicotinic Acetylcholine Receptor Expression and Activity During Neuronal Differentiation of PC12 Pheochromocytoma Cells. Journal of Molecular Neuroscience , v. 41, p. 329-339, 2010.

• Nery, Arthur A. ; Wrenger, Carsten ; Ulrich, Henning . Recognition of biomarkers and cell-specific molecular signatures: Aptamers as capture agents. Journal of Separation Science (Print) , v. 32, p. 1523-1530, 2009.

• Nery, Arthur A. ; Trujillo, Cleber A. ; Lameu, Claudiana ; Konno, Katsuhiro ; Oliveira, Vitor ; Camargo, Antonio C.M. ; Ulrich, Henning ; Hayashi, Mirian A.F. . A novel physiological property of snake bradykinin-potentiating peptides Reversion of MK-801 inhibition of nicotinic acetylcholine receptors. Peptides (New York, N.Y. 1980) , v. 29, p. 1708-1715, 2008.

• Ulrich, H. ; Akk, G. ; Nery, A.A. ; Trujillo, C.A. ; Rodriguez, A.D. ; Eterovi?, V.A. . Mode of cembranoid action on embryonic muscle acetylcholine receptor. Journal of Neuroscience Research , v. 86, p. 93-107, 2008.

• TRUJILLO, Cleber Augusto ; NERY, Arthur Andrade ; ALVES, J. M. ; MARTINS, Antonio Henrique Baccin ; ULRICH, Alexander Henning . Development of the anti-VEGF aptamer to a therapeutic agent for clinical ophthalmology.. Clinical ophthalmology , v. 1(4), p. 393-402, 2007.

• Trujillo, Cleber A. ; Nery, Arthur A. ; Martins, Antonio Henrique B. ; MAJUMDER, Paromita ; Gonzalez, Fernando A. ; Ulrich, Henning . Inhibition Mechanism of the Recombinant Rat P2X Receptor in Glial Cells by Suramin and TNP-ATP. Biochemistry (Easton) , v. 45, p. 224-233, 2006.

• ULRICH, Alexander Henning ; TRUJILLO, Cleber Augusto ; NERY, Arthur Andrade ; ALVES, J. M. ; MAJUMDER, Paromita ; RESENDE, Rodrigo Ribeiro ; MARTINS, Antonio Henrique Baccin . DNA and RNA aptamers: from tools for basic research towards therapeutic applications.. Combinatorial Chemistry & High Throughput Screening , v. 9(8), p. 619-632, 2006.

• MAGDESIAN, M. H. ; Nery, Arthur A. . Peptide Blockers of the Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Amyloid . The Journal of Biological Chemistry (Print) , USA, v. 280, n.35, p. 31085-31090, 2005.

• YUAHASI, K. K. ; Gomes KN ; Campos, M. ; Nery, A.A. ; NUNES-ALVES, A. ; TRUJILLO, Cleber ; Ulrich, H. . Neurotransmitters as Main Players in the Neural Differentiation and Fate Determination Game. In: Yuahasi KK ; GOMES KN; Campos M; NERY AA; Nunes-Alves A; TRUJILLO CA; ULRICH H. (Org.). Perspectives of Stem Cells - From tools for studying mechanisms of neuronal differentiation towards therapy.. 1ed.Dordrecht Heidelberg London Ne: Springer Science + Business Media, 2010, v. 1, p. 115-134.

• HAYASHI, M. A. F. ; NERY, Arthur Andrade ; CAMARGO, A. C. M. ; ULRICH, Alexander Henning . Novel roles of highly specific natural inhibitors of the angiotensin-converting enzyme. In: Evelyne BENOIT, Françoise GOUDEY-PERRIERE, Pascale MARCHOT et Denis SERVENT. (Org.). Toxines et fonctions cholinergiques neuronales et non neuronales.. Paris: Société Française pour l'Etude des Toxines, 2009, v. 16, p. 47-54.

• NERY, Arthur Andrade ; TRUJILLO, Cleber Augusto ; GOMES, C. L. ; KONNO, K. ; OLIVEIRA, V. ; CAMARGO, A. C. M. ; ULRICH, Alexander Henning ; HAYASHI, M. A. F. . A novel physiological property of snake bradkynin-potentiating peptides-reversion of MK-801 inhibition of nicotinic acetylcholine receptors. In: XXIV Reunião anual Federação de Sociedades de Biologia Experimental, 2009, Aguas de Lindoia. XXIV Reunião anual Federação de Sociedades de Biologia Experimental, 2009.

• NERY, Arthur Andrade ; GOMES, C. L. ; TRUJILLO, Cleber Augusto ; KONNO, K. ; CAMARGO, A. C. M. ; ULRICH, Alexander Henning ; HAYASHI, M. A. F. . Nicotinic acetylcholine receptor modulation by a snake toxin.. In: XIII International Symposium on Cholinergic Mechanisms, 2008, Foz do Iguaçu. XIII International Symposium on Cholinergic Mechanisms, 2008.

• NERY, Arthur Andrade ; RESENDE, Rodrigo Ribeiro ; TRUJILLO, Cleber ; MARTINS, Antônio Henrique Baccini ; ULRICH, Alexander Henning . Detection of alpha 7 receptor expression and activity during differentiation of PC12 cells to neurons. In: XXXV Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular, 2006, Águas de Lindoia. XXXV Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular, 2006. v. 1.

• NERY, Arthur Andrade ; TRUJILLO, Cleber Augusto ; GOMES, C. L. ; MARTINS, Antonio Henrique Baccin ; KONNO, K. ; CAMARGO, A. C. M. ; ULRICH, Alexander Henning ; HAYASHI, M. A. F. . A Novel Physiological Property of the Snake Bradykinin-Potentiating Peptides as Allosteric Protectors of Nicotinic Acetylcholine Receptor Activity. In: XXXV Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular, 2006, Águas de Lindoia. XXXV Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular, 2006. v. 1.

• NERY, Arthur Andrade ; SZETO, A. C. ; ETEROVIC, V. A. ; ULRICH, Alexander Henning . Effects of Tobacco Cembranoid 4S, 6R-Cembratrienediol on Nicotinic Acetylcholine Receptors in PC12 Cells. In: XXXV Reunião Anual da Sociedade de Brasileira de Bioquímica e Biologia Molecular, 2006, Águas de Lindoia. XXXV Reunião Anual da Sociedade de Brasileira de Bioquímica e Biologia Molecular, 2006. v. 1.

• NERY, Arthur Andrade ; RESENDE, Rodrigo Ribeiro ; MARTINS, Antonio Henrique Baccin ; TRUJILLO, Cleber Augusto ; ULRICH, Alexander Henning . Detecção e Funcionalidade dos receptors nicotínicos de acetilcolina durante a difereciação neuronal de células de feocromocitoma.. In: 13ª Jornada Nacional de Iniciação Científica, 58ª Reunião anual da Sociedade Brasileira para o Progresso da Ciência, 2006, Florianópolis. 58ª Reunião anual da Sociedade Brasileira para o Progresso da Ciência, 2006.

• NERY, Arthur Andrade ; RESENDE, Rodrigo Ribeiro ; MARTINS, Antonio Henrique Baccin ; TRUJILLO, Cleber Augusto ; ULRICH, Alexander Henning . Detection of alpha 7 receptor expression and activity during differentiation of PC12 cells to neurons.. In: 16th Biennial Meeting of the International Society for Developmental Neuroscience, 2006, Banff. 16th Biennial Meeting of the International Society for Developmental Neuroscience. Oxford: Elsevier, 2006. v. 1. p. P180.

• NERY, Arthur Andrade ; MARTINS, Antônio Henrique Baccini ; RESENDE, Rodrigo ; TRUJILLO, Cleber Augusto ; ULRICH, Alexander Henning . Detection and functionality of nicotinic acetylcholine receptores during neuronal differentiaion of PC12 pheochromocytoma cells. In: XXXIV-Reuniao Anual da Sociedade Brasileira e Biologia Molecular - SBBq, 2005, Aguas de Lindoia. XXXIV-Reuniao Anual da Sociedade Brasileira e Biologia Molecular - SBBq, 2005.

• NERY, Arthur Andrade ; MARTINS, Antonio Henrique Baccin ; TRUJILLO, Cleber ; ULRICH, Alexander Henning . Detection and functionality of nicotinic acetylcholine receptors during neuroanl differentiation of PC12 pheocromocytoma cells. In: FESBE, 2005, Aguas de lindoia. FESBE 2005, 2005.

• NERY, Arthur Andrade ; MARTINS, Antonio Henrique Baccin ; RESENDE, Rodrigo ; TRUJILLO, Cleber ; ULRICH, Alexander Henning . Detection and funcionality of nicotinic acetylcholine receptor subunities during PC12 neuronal differentiation. In: 2nd International Meeting of the Latin American Society of Developmental Biology, 2005, Guaruja. 2nd International Meeting of the Latin American Society of Developmental Biology Program and Abstracts, 2005. v. 1. p. 41-41.

• NERY, Arthur Andrade ; RESENDE, Rodrigo ; MARTINS, Antonio Henrique Baccin ; ULRICH, Alexander Henning . Detecção e funcionalidade dos receptores nicotínicos de acetilcolina durante a diferenciação neuronal decélulas de feocromocitoma PC12. In: 13o. SIICUSP, 2005, Ribeirao Preto. 13o. SIICUSP, 2005.

• RESENDE, Rodrigo Ribeiro ; MARTINS, Antonio Henrique Baccin ; NERY, Arthur Andrade ; ULRICH, Alexander Henning . Nicotinic and muscarinic cholinergic receptors subunits are expressed during neuronal differentiation of P19 embryonal carcinoma cells. In: XXXIV Reuniao Anual da Sociedade Brasileira de Bioquimica e Biologia Molecular, 2005, Aguas de Lindoia. XXXIV Reuniao Anual da Sociedade Brasileira de Bioquimica e Biologia Molecular, 2005.

• MAGDESIAN, M. H. ; NERY, Arthur Andrade ; MARTINS, Antonio Henrique Baccin ; JULIANO, M. A. ; JULIANO, L. ; ULRICH, Alexander Henning ; FERREIRA, S. T. . Peptides Blockers of the inhibition of neuronal nicotinic acetylchline receptors by beta-amyloid peptide. In: XXXIV Reuniao Anual da Sociedade Brasileira de Bioquimica e Biologia Molecular, 2005, Aguas de Lindoia. XXXIV Reuniao Anual da Sociedade Brasileira de Bioquimica e Biologia Molecular, 2005.

• TRUJILLO, Cleber ; MAJUMDER, Paromita ; NERY, Arthur Andrade ; ULRICH, Alexander Henning . Pharmacoligical properties of suramin in glial cells expressing the recombinant rat P2X2 receptor. In: XXXIV Reuniao Anual da Sociedade Brasileira de Bioquimica e Biologia Molecular, 2005, Aguas de Lindoia. XXXIV Reuniao Anual da Sociedade Brasileira de Bioquimica e Biologia Molecular, 2005.

• NERY, Arthur Andrade ; MARTINS, Antônio Henrique Baccini ; RESENDE, Rodrigo ; MAJUMDER, Paromita ; TRUJILLO, Cleber ; ULRICH, Alexander Henning . Expressão e funcionalidade de receptores nicotínicos neurais de acetilcolina durante o processo de diferenciação de células PC12. In: SIICUSP, 2004, `Ribeirão Preto. 12o SIICUSP, 2004. v. 1.

• NERY, Arthur Andrade . CHARACTERIZATION OF NATURAL ENDOOLIGOPEPTIDASE A COMPLEXES IN THE CENTRAL NERVOUS SYSTEM.. In: SBBq, 2003, Caxumbú. SBBq / Programa e Resumos da XXXII Reunião Anual / 2003, 2003. v. 1. p. 234-234.

Outras produções

Projetos de pesquisa

• 2002 - 2006

  Detection and functionality of nicotinic acetylcholine receptors during neuronal differentiation of PC12 pheochromocytoma cells, Descrição: The present work aims at the characterization of expression and functionality of nicotinic acetylcholine receptors during neuronal differentiation of PC12 cells. Gene expression was detected and quantified by real-time PCR and receptor functionality was confirmed by voltage clamp whole-cell recordings. A cloned line of rat pheochromocytoma cells (PC12) is a widely accepted model system for studying neuronal differentiation in vitro. In the presence of nerve growth factor (NGF) PC12 initiate neuronal differentiation and express nicotinic acetylcholine receptors. However, in the presence of basic fibroblast growth factor (bFGF) and dibutyril-cAMP instead of NGF, the responsiveness of nAChR stimulation by its agonist carbamoylcholine increased compared to cells differentiated in the presence of NGF as determined by fast-kinetic whole-cell recording. These data indicate that nicotinic receptor functionality depends on the used differentiation protocol. Our results showed that the function and the expression of the nAChR subunits are modulated during the course of neuronal differentiation. Functional tests showed that PC12 cells during the course of neuronal differentiation show increasing responses to their agonist carbamoylcholine regarding receptor desensitization to stimulation by carbamoylcholine. Differentiation is aborted in the presence of the 4S tobacco cembranoide, a specific nAChR inhibitor, implicating the importance of nicotinic receptor function during neuronal differentiation of PC12 cells. Supported by FAPESP and CNPq . , Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (1) / Especialização: (0) / Mestrado acadêmico: (1) / Mestrado profissional: (0) / Doutorado: (1) . , Integrantes: Arthur Andrade Nery - Integrante / Antonio Henrique Baccin Martins - Integrante / Rodrigo Ribeiro Resende - Integrante / Cleber Augusto Trujillo - Integrante / Alexander Henning Ulrich - Coordenador., Financiador(es): Conselho Nacional de Desenvolvimento Científico e Tecnológico - Bolsa / Fundação de Amparo à Pesquisa do Estado de São Paulo - Auxílio financeiro., Número de produções C, T & A: 5

Projetos de desenvolvimento

• 2007 - 2011

  Separação de células tronco de lipoaspirado humano por aptâmeros de DNA, seguida da caracterização dos fenótipos obtidos da diferenciação neuronal., Descrição: Projeto que busca entender o processo de diferenciação de células tronco mesenquimais de tecido adiposo em células com morfologia e funcionalidade neuronais, assim como desenvolver um método baseado em aptâmeros de isolamento dessas células para sua viabilização em uso clínico.. , Situação: Em andamento; Natureza: Desenvolvimento. , Integrantes: Arthur Andrade Nery - Integrante / Alexander Henning Ulrich - Integrante / José Eduardo Krieger - Coordenador.

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