Arif Ali

Idiomas

Áreas de atuação

Organização de eventos

Participação em eventos

Produções bibliográficas

• VIANA, GLAUTEMBERG DE ALMEIDA ; COSTA, MAC DIONYS RODRIGUES DA ; SILVA, MATEUS EDSON DA ; SILVA, VICTÓRIA DA COSTA ; ALI, ARIF ; SIQUEIRA, ERLÂNIA ALVES DE ; ALVES, RENATA DE SOUSA ; Martins, Alice Maria Costa ; MENEZES, RAMON RÓSEO PAULA PESSOA BEZERRA DE ; QUEIROZ, MARIA GORETTI RODRIGUES DE ; SAMPAIO, TIAGO LIMA . Association of serum lipoproteins and inflammatory parameters derived from the blood test with renal function in COVID-19 outpatients. BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES (ONLINE) , v. 59, p. 59:e23293, 2023.

• DUTRA BARROSO GOMES, NAIARA ; PAULA MAGALHÃES, EMANUEL ; RODRIGUES RIBEIRO, LYANNA ; CAVALCANTE, JOHN WASHINGTON ; MORAIS GOMES MAIA, MARCELO ; CUNHA DA SILVA, FELIPE RAMON ; ALI, ARIF ; MACHADO MARINHO, MÁRCIA ; SILVA MARINHO, EMMANUEL ; SILVA DOS SANTOS, HÉLCIO ; COSTA MARTINS, ALICE MARIA ; RÓSEO PAULA PESSOA BEZERRA DE MENEZES, RAMON . Trypanocidal potential of synthetic p-aminochalcones: In silico and in vitro evaluation. BIOORGANIC CHEMISTRY , v. 141, p. 106931, 2023.

• DACREMA, MARCO ; ALI, ARIF ; ULLAH, HAMMAD ; KHAN, AYESHA ; DI MINNO, ALESSANDRO ; XIAO, JIANBO ; Martins, Alice Maria Costa ; DAGLIA, MARIA . Spice-Derived Bioactive Compounds Confer Colorectal Cancer Prevention via Modulation of Gut Microbiota. Cancers , v. 14, p. 5682, 2022.

• MAGALHÃES, EMANUEL PAULA ; SILVA, BRENNA PINHEIRO ; AIRES, NATÁLIA LUNA ; RIBEIRO, LYANNA RODRIGUES ; ALI, ARIF ; CAVALCANTI, MARIANA MACIEL ; NUNES, JOÃO VICTOR SERRA ; SAMPAIO, TIAGO LIMA ; DE MENEZES, RAMON RÓSEO PAULA PESSOA BEZERRA ; Martins, Alice Maria Costa . ()--Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B. LIFE SCIENCES , v. 291, p. 120271, 2022.

• ALI, ARIF ; KHAN, HAROON ; KAHRIZI, DANIAL ; PERVEZ, SAMREEN ; ALOTAIBI, GHALLAB ; RASTRELLI, LUCA . Nephroprotective effects of Helianthus annuus seeds extract in gentamicin induced nephrotoxic male mice. CELLULAR AND MOLECULAR BIOLOGY (ONLINE) , v. 68, p. 1-7, 2022.

• ALI, ARIF ; LIMA SAMPAIO, TIAGO ; KHAN, HAROON ; JEANDET, PHILIPPE ; KÜPELI AKKOL, ESRA ; BAHADAR, HUMAIRA ; COSTA MARTINS, ALICE MARIA . Plants with Therapeutic Potential for Ischemic Acute Kidney Injury: A Systematic Review. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (ONLINE) , v. 2022, p. 1-22, 2022.

• ALI, ARIF ; Rodrigues da Costa, Mac Dionys ; MAGALHÃES, EMANUEL PAULA ; COSTA MARTINS, ALICE MARIA . Chapter 4 Biological importance of vitamins and minerals. Nutraceuticals. 1ed.: De Gruyter, 2024, v. , p. 63-102.

• Abdullah, ; Alam, Waqas ; Hussain, Yaseen ; Ahmad, Saeed ; khan, Faizullah ; ALI, ARIF ; KHAN, HAROON . Neuroprotective effect of essential oils. Phytonutrients and Neurological Disorders. 1ed.: Elsevier, 2023, v. , p. 305-333.

• ALI, ARIF ; Martins, Alice Maria Costa ; Alam, Waqas ; KHAN, HAROON . Neuroprotective effects of alkaloids. Phytonutrients and Neurological Disorders. 1ed.: Elsevier, 2023, v. , p. 245-257.

• Alam, Waqas ; ALI, ARIF ; khan, Faizullah ; COSTA MARTINS, ALICE MARIA ; Hussain, Yaseen ; KHAN, P. D. H. . Role of Quercetin in DNA Repair and Dysregulated Metabolism. Possible Target to Combat Drug Resistance in Cancer. Phytonutrients, 2022 (Preprint).

Outras produções

Projetos de pesquisa

• 2020 - 2024

  Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation, Descrição: Ischemia reperfusion (I/R) is the main cause of acute kidney injury, contributing to higher rate of mortality and morbidity around the globe. Renal I/R injury involves complex pathophysiology. However, generation of reactive oxygen species (ROS) are supposed as the common pathological alteration during I/R injury. Therefore, targeting generation of ROS, protecting mitochondria and improving organ function are the main interventions to manage I/R induced AKI. Chalcones belonging to flavonoid family of phenolic compounds are abundantly found in numerous fruits, dietary spices, teas and soya-based foods. Chalcones derivatives are studied widely due to their simple structure and numerous biological activities such as antioxidant, anti-inflammatory, anti-microbial, anticancer, antidiabetic, psychoactive and neuroprotective actions. Therefore, considering strong antioxidant action along with other pharmacological roles of chalcone derivatives, 2-hydroxy chalcones were synthesized and then analyzed for their nephroprotective role in I/R induced AKI. The main objective of the study was to evaluate the role 2-hydroxy chalcones in treatment and prevention of I/R induced AKI by targeting main pathological pathways including generation of ROS, apoptosis, necrosis and antioxidant system. Cell viability was analyzed via MTT assay, followed by flow cytometry for apoptosis, necrosis, ROS generation and mitochondrial transmembrane potential measurement. The affect of chalcones on oxidation reduction system was also evaluated by analyzing its effect on TBARS, GSH and SOD. The effect of chalcone on cells morphological features were studied via scanning electron microscopy. Moreover, chalcone interaction with NOX4 subunit of NADPH oxidase was also evaluated via molecular docking.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (3) / Especialização: (7) / Mestrado acadêmico: (1) / Mestrado profissional: (1) / Doutorado: (1) . , Integrantes: Arif Ali - Integrante / Martins, Alice Maria Costa - Coordenador.

• 2017 - 2019

  Nephroprotective role of Helianthus Annuus, Descrição: Helianthus Annuus seeds was collected and one part was extracted with methanol while the other part was extracted with n-hexane. Both of the extracts were applied in mice model for their nephroprotective role against gentamicin induced nephrotoxicity. The nephroprotecttive role was estimated from measuring blood biomarker (serum creatinine, BUN) and kidney histopathology. The results were compared with the standard nephroprotective agent Salymarin.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (1) / Mestrado profissional: (1) . , Integrantes: Arif Ali - Coordenador / Prof. Dr. Haroon Khan - Integrante.