Rafael Lemos Miguez Counago

Pós-doutorado

Formação complementar

Idiomas

Áreas de atuação

Participação em eventos

Participação em bancas

Orientou

Produções bibliográficas

• ONG, HAN WEE ; YANG, XUAN ; SMITH, JEFFERY L. ; DICKMANDER, REBEKAH J. ; BROWN, JASON W. ; HAVENER, TAMMY M. ; TAFT-BENZ, SHARON ; HOWELL, STEFANIE ; SANDERS, MARCIA K. ; CAPENER, JACOB L. ; Couñago, Rafael M. ; CHANG, EDCON ; KRÄMER, ANDREAS ; MOORMAN, NATHANIEL J. ; HEISE, MARK ; AXTMAN, ALISON D. ; DREWRY, DAVID H. ; WILLSON, TIMOTHY M. . More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication. JOURNAL OF MEDICINAL CHEMISTRY , v. 67, p. 12261-12313, 2024.

• CUNHA, MICAEL R. ; DO AMARAL, BRUNO S. ; TAKARADA, JÉSSICA E. ; VALDERRAMA, GABRIEL V. ; BATISTA, ANDREA N. L. ; BATISTA, JOÃO M. ; CASS, QUEZIA B. ; Couñago, Rafael M. ; MASSIRER, KATLIN B. . ( S )-ML-SA1 Activates Autophagy via TRPML1-TFEB Pathway. ChemBioChem , v. 1, p. e202400506, 2024.

• DE SOUZA GAMA, FERNANDO H. ; DUTRA, LUIZ A. ; HAWGOOD, MICHAEL ; DOS REIS, CAIO VINÍCIUS ; SERAFIM, RICARDO A. M. ; FERREIRA, MARCOS A. ; TEODORO, BRUNO V. M. ; TAKARADA, JÉSSICA EMI ; SANTIAGO, ANDRÉ S. ; BALOURDAS, DIMITRIOS-ILIAS ; NILSSON, ANN-SOFIE ; URIEN, BRUNO ; ALMEIDA, VITOR M. ; GILEADI, CARINA ; RAMOS, PRISCILA Z. ; SALMAZO, ANITA ; VASCONCELOS, STANLEY N. S. ; CUNHA, MICAEL R. ; MUELLER, SUSANNE ; COUÑAGO, R. L. M. . Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε. JOURNAL OF MEDICINAL CHEMISTRY , v. 67, p. 8609-8629, 2024.

• TAKARADA, JÉSSICA E. ; CUNHA, MICAEL R. ; ALMEIDA, VITOR M. ; VASCONCELOS, STANLEY N.S. ; SANTIAGO, ANDRÉ S. ; GODOI, PAULO H. ; SALMAZO, ANITA ; RAMOS, PRISCILA Z. ; FALA, ANGELA M. ; DE SOUZA, LUCAS R. ; DA SILVA, ITALO E.P. ; BENGTSON, MARIO H. ; MASSIRER, KATLIN B. ; Couñago, Rafael M. . Discovery of pyrazolo[3,4-d]pyrimidines as novel mitogen-activated protein kinase kinase 3 (MKK3) inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY , v. 98, p. 117561, 2024.

• MEIRELLES, MATHEUS A. ; DE TOLEDO, IAN ; THUROW, SAMUEL ; BARREIRO, GABRIELA ; Couñago, Rafael M. ; PILLI, RONALDO A. . Functionalization of 2,4-Dichloropyrimidines by 2,2,6,6-Tetramethylpiperidyl Zinc Base Enables Modular Synthesis of Antimalarial Diaminopyrimidine P218 and Analogues. JOURNAL OF ORGANIC CHEMISTRY (ONLINE) , v. 1, p. 3c00500, 2023.

• MARCELINO, TIAGO DE PAULA ; FALA, ANGELA MARIA ; DA SILVA, MATHEUS MONTEIRO ; SOUZA-MELO, NORMANDA ; MALVEZZI, AMARANTA MUNIZ ; KLIPPEL, ANGÉLICA HOLLUNDER ; ZOLTNER, MARTIN ; PADILLA-MEJIA, NORMA ; KOSTO, SAMANTHA ; FIELD, MARK C. ; BURLE CALDAS, GABRIELA DE ASSIS ; TEIXEIRA, SANTUZA MARIA RIBEIRO ; Couñago, Rafael Miguez ; MASSIRER, KATLIN BRAUER ; SCHENKMAN, SERGIO . Identification of inhibitors for the trans-membrane Trypanosoma cruzi eIF2α kinase relevant for parasite proliferation. JOURNAL OF BIOLOGICAL CHEMISTRY , v. 1, p. 104857, 2023.

• CUNHA, MICAEL R. ; CATTA-PRETA, CAROLINA M.C. ; TAKARADA, JÉSSICA E. ; MOREIRA, GABRIELA A. ; MASSIRER, KATLIN B. ; Couñago, Rafael M. . A novel BRET-based assay to investigate binding and residence times of unmodified ligands to the human lysosomal ion channel TRPML1 in intact cells. JOURNAL OF BIOLOGICAL CHEMISTRY , v. 1, p. 104807, 2023.

• TOMAZ, KAIRA C. P. ; TAVELLA, TATYANA A. ; BORBA, JOYCE V. B. ; SALAZAR-ALVAREZ, LUIS C. ; LEVANDOSKI, JOÃO E. ; MOTTIN, MELINA ; SOUSA, BRUNA K. P. ; MOREIRA-FILHO, JOSÉ T. ; ALMEIDA, VITOR M. ; CLEMENTINO, LEANDRO C. ; BOURGARD, CATARINA ; MASSIRER, KATLIN B. ; Couñago, Rafael M. ; ANDRADE, CAROLINA H. ; SUNNERHAGEN, PER ; BILSLAND, ELIZABETH ; CASSIANO, GUSTAVO C. ; COSTA, FABIO T. M. . Identification of potential inhibitors of casein kinase 2 alpha of Plasmodium falciparum with potent in vitro activity. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY , v. 67, p. e00589-23, 2023.

• WELLS, CARROW ; LIANG, YI ; PULLIAM, THOMAS L. ; LIN, CHENCHU ; AWAD, DOMINIK ; EDUFUL, BENJAMIN ; O?BYRNE, SEAN ; HOSSAIN, MOHAMMAD ANWAR ; COSTA-PRETA, CAROLINA MOURA ; RAMOS, PRISCILA ZONZINI ; GILEADI, OPHER ; GILEADI, CARINA ; Couñago, Rafael M. ; STORK, BRITTANY ; LANGENDORF, CHRISTOPHER G. ; NAY, KEVIN ; OAKHILL, JONATHAN S. ; MUKHERJEE, DEBARATI ; RACIOPPI, LUIGI ; MEANS, ANTHONY . SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Cells , v. 12, p. 287, 2023.

• Ercoli M.F. ; RAMOS, PRISCILA Z. ; Jain R. ; Pilotte J. ; Dong O.X ; Thompson T. ; WELLS, CARROW I. ; ELKINS, JONATHAN M. ; Edwards A.M. ; COUÑAGO, RAFAEL M. ; DREWRY, DAVID H. ; Ronald PC . An open source plant kinase chemogenomics set. Plant Direct , v. 6, p. e460, 2022.

• FANTI, REBEKA C. ; VASCONCELOS, STANLEY N. S. ; CATTA-PRETA, CAROLINA M. C. ; SULLIVAN, JARYD R. ; RIBOLDI, GUSTAVO P. ; DOS REIS, CAIO V. ; RAMOS, PRISCILA Z. ; EDWARDS, ALED M. ; BEHR, MARCEL A. ; Couñago, Rafael M. . A Target Engagement Assay to Assess Uptake, Potency, and Retention of Antibiotics in Living Bacteria. ACS Infectious Diseases , v. 8, p. 1449-1467, 2022.

• SEGRETTI, NATANAEL D. ; TAKARADA, JÉSSICA E. ; FERREIRA, MARCOS A. ; DA SILVA SANTIAGO, ANDRÉ ; TEODORO, BRUNO V.M. ; DAMIÃO, MARIANA C.F.C.B. ; GODOI, PAULO H. ; CUNHA, MICAEL R. ; FALA, ANGELA M. ; RAMOS, PRISCILA Z. ; ISHIKAWA, ELOISA E. ; MASCARELLO, ALESSANDRA ; SERAFIM, RICARDO A.M. ; AZEVEDO, HATYLAS ; GUIMARÃES, CRISTIANO R.W. ; Couñago, Rafael M. . Discovery of novel benzothiophene derivatives as potent and narrow spectrum inhibitors of DYRK1A and DYRK1B. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , v. 68, p. 128764, 2022.

• M. SERAFIM, RICARDO A. ; DA SILVA SANTIAGO, ANDRÉ ; SCHWALM, MARTIN P. ; HU, ZEXI ; DOS REIS, CAIO V. ; TAKARADA, JESSICA E. ; MEZZOMO, PRISCILA ; MASSIRER, KATLIN B. ; KUDOLO, MARK ; GERSTENECKER, STEFAN ; CHAIKUAD, APIRAT ; ZENDER, LARS ; KNAPP, STEFAN ; LAUFER, STEFAN ; Couñago, Rafael M. ; GEHRINGER, MATTHIAS . Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor. JOURNAL OF MEDICINAL CHEMISTRY , v. 65, p. 3173-3192, 2022.

• SCOTT, FIONA ; FALA, ANGELA M. ; TAKARADA, JESSICA E. ; FICU, MIHAELA P. ; PENNICOTT, LEWIS E. ; REUILLON, TRISTAN D. ; Couñago, Rafael M. ; MASSIRER, KATLIN B. ; ELKINS, JONATHAN M. ; WARD, SIMON E. . Development of dihydropyrrolopyridinone-based PKN2/PRK2 chemical tools to enable drug discovery. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , v. 60, p. 128588, 2022.

• EDUFUL, BENJAMIN J. ; O?BYRNE, SEAN N. ; TEMME, LOUISA ; ASQUITH, CHRISTOPHER R. M. ; LIANG, YI ; PICADO, ALFREDO ; PILOTTE, JOSEPH R. ; HOSSAIN, MOHAMMAD ANWAR ; WELLS, CARROW I. ; ZUERCHER, WILLIAM J. ; CATTA-PRETA, CAROLINA M. C. ; ZONZINI RAMOS, PRISCILA ; SANTIAGO, ANDRÉ DE S. ; Couñago, Rafael M. ; LANGENDORF, CHRISTOPHER G. ; NAY, KÉVIN ; OAKHILL, JONATHAN S. ; PULLIAM, THOMAS L. ; LIN, CHENCHU ; AWAD, DOMINIK . Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes. JOURNAL OF MEDICINAL CHEMISTRY , v. 64, p. 10849-10877, 2021.

• FERREIRA, TIAGO R. ; Couñago, Rafael M. ; MORETTI, NILMAR S. . Raising the Bar(-seq) in Leishmania Genetic Screens. TRENDS IN PARASITOLOGY , v. 37, p. 367-369, 2021.

• CABARCA, SINDY ; FRAZÃO DE SOUZA, MAXIMILIA ; ALBERT DE OLIVEIRA, ANDREW ; VIGNOLI MUNIZ, GABRIEL S. ; LAMY, M. TERESA ; VINICIUS DOS REIS, CAIO ; TAKARADA, JESSICA ; EFFER, BRIAN ; SOUZA, LUCAS SANTOS ; IRIARTE DE LA TORRE, LILIA ; Couñago, Rafael ; PINTO OLIVEIRA, CRISTIANO LUIS ; BALAN, ANDREA . Structure of the Mycobacterium tuberculosis cPknF and conformational changes induced in forkhead-associated regulatory domains. Current Research in Structural Biology , v. 3, p. 165-178, 2021.

• O?BYRNE, SEAN N. ; SCOTT, JOHN W. ; PILOTTE, JOSEPH R. ; SANTIAGO, ANDRÉ DA S. ; LANGENDORF, CHRISTOPHER G. ; OAKHILL, JONATHAN S. ; EDUFUL, BENJAMIN J. ; Couñago, Rafael M. ; WELLS, CARROW I. ; ZUERCHER, WILLIAM J. ; WILLSON, TIMOTHY M. ; DREWRY, DAVID H. . In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds. MOLECULES , v. 25, p. 325, 2020.

• BARRETO, PEDRO ; Couñago, Rafael M. ; ARRUDA, PAULO . Mitochondrial uncoupling protein-dependent signaling in plant bioenergetics and stress response. MITOCHONDRION , v. 53, p. 109-120, 2020.

• SILVA, SUÉLEN FERNANDES ; KLIPPEL, ANGÉLICA HOLLUNDER ; RAMOS, PRISCILA ZONZINI ; SANTIAGO, ANDRÉ DA SILVA ; VALENTINI, SANDRO ROBERTO ; BENGTSON, MARIO HENRIQUE ; MASSIRER, KATLIN BRAUER ; BILSLAND, ELIZABETH ; Couñago, Rafael Miguez ; ZANELLI, CLESLEI FERNANDO . Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major. PLoS Neglected Tropical Diseases , v. 14, p. e0008762, 2020.

• RIBOLDI, GUSTAVO P. ; ZIGWEID, RACHAEL ; MYLER, PETER J. ; MAYCLIN, STEPHEN J. ; Couñago, Rafael M. ; STAKER, BART L. . Identification of P218 as a potent inhibitor of DHFR. Rsc Medicinal Chemistry , v. 12, p. 103-109, 2020.

• ALVES, FERNANDO RODRIGUES DE SÁ ; Couñago, Rafael M. ; LAUFER, STEFAN . Chemical Space Exploration of Oxetanes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , v. 21, p. 8199, 2020.

• AGAJANIAN, MEGAN J. ; WALKER, MATTHEW P. ; AXTMAN, ALISON D. ; RUELA-DE-SOUSA, ROBERTA R. ; SERAFIN, D. STEPHEN ; RABINOWITZ, ALEX D. ; GRAHAM, DAVID M. ; RYAN, MEAGAN B. ; TAMIR, TIGIST ; NAKAMICHI, YUKO ; GAMMONS, MELISSA V. ; BENNETT, JAMES M. ; Couñago, Rafael M. ; DREWRY, DAVID H. ; ELKINS, JONATHAN M. ; GILEADI, CARINA ; GILEADI, OPHER ; GODOI, PAULO H. ; KAPADIA, NIRAV ; MÜLLER, SUSANNE . WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop. Cell Reports , v. 26, p. 79-93.e8, 2019.

• PROFETA, GERSON S. ; DOS REIS, CAIO V. ; SANTIAGO, ANDRÉ DA S. ; GODOI, PAULO H. C. ; FALA, ANGELA M. ; WELLS, CARROW I. ; SARTORI, ROGER ; SALMAZO, ANITA P. T. ; RAMOS, PRISCILA Z. ; MASSIRER, KATLIN B. ; ELKINS, JONATHAN M. ; DREWRY, DAVID H. ; GILEADI, OPHER ; Couñago, Rafael M. . Binding and structural analyses of potent inhibitors of the human Ca2+/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors. Scientific Reports , v. 9, p. 16452, 2019.

• RIGHETTO, GERMANNA LIMA ; SRIRANGANADANE, DEV ; HALABELIAN, LEVON ; CHIODI, CARLA G. ; ELKINS, JONATHAN M. ; MASSIRER, KATLIN B. ; GILEADI, OPHER ; MENOSSI, MARCELO ; Couñago, Rafael M. . The C-Terminal Domains SnRK2 Box and ABA Box Have a Role in Sugarcane SnRK2s Auto-Activation and Activity. Frontiers in Plant Science , v. 10, p. 1105, 2019.

• SERAFIM, RICARDO A. M. ; DE SOUZA GAMA, FERNANDO H. ; DUTRA, LUIZ A. ; DOS REIS, CAIO V. ; VASCONCELOS, STANLEY N. S. ; DA SILVA SANTIAGO, ANDRÉ ; TAKARADA, JÉSSICA E. ; DI PILLO, FÚLVIA ; AZEVEDO, HATYLAS ; MASCARELLO, ALESSANDRA ; ELKINS, JONATHAN M. ; MASSIRER, KATLIN B. ; GILEADI, OPHER ; GUIMARÃES, CRISTIANO R. W. ; Couñago, Rafael M. . Development of Pyridine-based Inhibitors for the Human Vaccinia-related Kinases 1 and 2. ACS Medicinal Chemistry Letters , v. 9, p. 1266-1271, 2019.

• WELLS, CARROW ; Couñago, Rafael M. ; LIMAS, JUANITA C. ; ALMEIDA, TUANNY L. ; COOK, JEANETTE GOWEN ; DREWRY, DAVID H. ; ELKINS, JONATHAN M. ; GILEADI, OPHER ; KAPADIA, NIRAV R. ; LORENTE-MACIAS, ALVARO ; PICKETT, JULIE E. ; RIEMEN, ALEXANDER ; RUELA-DE-SOUSA, ROBERTA R. ; WILLSON, TIMOTHY M. ; ZHANG, CUNYU ; ZUERCHER, WILLIAM J. ; ZUTSHI, REENA ; AXTMAN, ALISON D. . SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K. ACS Medicinal Chemistry Letters , v. 9, p. acsmedchemlett.9b00399, 2019.

• TOSARINI, THALITA RAVAZO ; RAMOS, PRISCILA ZONZINI ; DE SOUZA, GERSON PROFETA ; BARONI, RENATA MORO ; MASSIRER, KATLIN B. ; Couñago, Rafael M. ; MONDEGO, JORGE M.C. . Cloning, expression and purification of kinase domains of cacao PR-1 receptor-like kinases. PROTEIN EXPRESSION AND PURIFICATION , v. 146, p. 78-84, 2018.

• WELLS, C. I. ; KAPADIA, N. R. ; COUÑAGO, R. M. ; DREWRY, D. H. . In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the Nek family of kinases. MedChemComm , v. 9, p. 44-66, 2018.

• SANTIAGO, ANDRÉ DA SILVA ; Couñago, Rafael M. ; RAMOS, PRISCILA ZONZINI ; GODOI, PAULO H. C. ; MASSIRER, KATLIN B. ; GILEADI, OPHER ; ELKINS, JONATHAN M. . Structural Analysis of Inhibitor Binding to CAMKK1 Identifies Features Necessary for Design of Specific Inhibitors. Scientific Reports , v. 8, p. 14800, 2018.

• ASQUITH, CHRISTOPHER ; GODOI, PAULO ; Couñago, Rafael ; LAITINEN, TUOMO ; SCOTT, JOHN ; LANGENDORF, CHRISTOPHER ; OAKHILL, JONATHAN ; DREWRY, DAVID ; ZUERCHER, WILLIAM ; KOUTENTIS, PANAYIOTIS ; WILLSON, TIMOTHY ; KALOGIROU, ANDREAS . 1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors. MOLECULES , v. 23, p. 1221, 2018.

• AQUINO, BRUNO ; Couñago, Rafael M. ; VERZA, NATALIA ; FERREIRA, LUCAS M. ; MASSIRER, KATLIN B. ; GILEADI, OPHER ; ARRUDA, PAULO . Structural Characterization of Maize SIRK1 Kinase Domain Reveals an Unusual Architecture of the Activation Segment. Frontiers in Plant Science , v. 8, p. 852, 2017.

• Couñago, Rafael M. ; ALLERSTON, CHARLES K. ; SAVITSKY, PAVEL ; AZEVEDO, HATYLAS ; GODOI, PAULO H. ; WELLS, CARROW I. ; MASCARELLO, ALESSANDRA ; DE SOUZA GAMA, FERNANDO H. ; MASSIRER, KATLIN B. ; ZUERCHER, WILLIAM J. ; GUIMARÃES, CRISTIANO R. W. ; GILEADI, OPHER . Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations. Scientific Reports , v. 7, p. 7501, 2017.

• Couñago, Rafael M. ; CHEN, NATHAN H. ; CHANG, CHIUNG-WEN ; DJOKO, KARRERA Y. ; MCEWAN, ALASTAIR G. ; KOBE, BOSTJAN . Structural basis of thiol-based regulation of formaldehyde detoxification in by a MerR regulator with no sensor region. NUCLEIC ACIDS RESEARCH , v. 44, p. 6981-6993, 2016.

• BEGG, S. L. ; EIJKELKAMP, BART A. ; LUO, Z. ; Counago, R.M. ; MOREY, JACQUELINE R. ; MAHER, M. J. ; O?MARA, M. L. ; ONG, C. Y. ; McEwan, AG ; KOBE, B. ; PATON, JAMES C. ; MCDEVITT, C. A. . Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nature Communications , v. 6, p. 6418, 2015.

• COUÑAGO, RAFAEL M. ; KNAPP, KAREN M. ; NAKATANI, YOSHIO ; FLEMING, STEPHEN B. ; CORBETT, MICHAEL ; WISE, LYN M. ; MERCER, ANDREW A. ; KRAUSE, KURT L. . Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal Clues to Broad Binding Specificity. Structure (London) , v. 23, p. 1199-1213, 2015.

• PLUMPTRE, CHARLES D. ; EIJKELKAMP, BART A. ; MOREY, JACQUELINE R. ; BEHR, FELIX ; Couñago, Rafael M. ; OGUNNIYI, ABIODUN D. ; KOBE, BOSTJAN ; O'MARA, MEGAN L. ; PATON, JAMES C. ; MCDEVITT, CHRISTOPHER A. . AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in. Molecular Microbiology (Print) , v. epub, p. n/a-n/a, 2014.

• CHANG, C.-W. ; WILLIAMS, S. J. ; COUNAGO, R. M. ; KOBE, B. . Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium VirD2 with Rice Importin- . Molecular Plant , v. epub, p. epub-epub, 2014.

• Chen, Stephen ; Couñago, Rafael M ; Karrera Y. Djoko ; JENNINGS, M. P. ; Apicella, MA ; KOBE, B. ; McEwan, AG . A Glutathione-Dependent Detoxification System Is Required for Formaldehyde Resistance and Optimal Survival of in Biofilms. Antioxidants & Redox Signalling , v. 18, p. 743-755, 2013.

• CHANG, C.-W. ; COUNAGO, R. L. M. ; WILLIAMS, S. J. ; BODEN, M. ; KOBE, B. . Crystal Structure of Rice Importin-  and Structural Basis of Its Interaction with Plant-Specific Nuclear Localization Signals. PLANT CELL , v. 24, p. 5074-5088, 2013.

• Chang, CW ; Couñago, Rafael M ; WILLIAMS, S. J. ; Bodén, M . The distribution of different classes of nuclear localization signals (NLSs) in diverse organisms and the utilization of the minor NLS-binding site inplantnuclear import factor importin-α. PLANT SIGNALING & BEHAVIOR , v. 8, p. e25976, 2013.

• Chang, CW ; Couñago, Rafael M. ; WILLIAMS, S. J. ; BODEN, M. ; KOBE, B. . Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-α. Traffic (Copenhagen. Print) , v. 14, p. n/a-n/a, 2013.

• Couñago, Rafael M. ; WEEN, M. P. ; BEGG, S. L. ; BAJAJ, M. ; ZUEGG, J. ; O?MARA, M. L. ; COOPER, M. A. ; McEwan, AG ; PATON, J. C. ; KOBE, B. ; MCDEVITT, C. A. . Imperfect coordination chemistry facilitates metal ion release in the psa permease. Nature Chemical Biology , v. AdvOnl, p. nchembio.1382, 2013.

• Couñago, Rafael M ; MCDEVITT, C. A. ; WEEN, M. P. ; KOBE, B. . Prokaryotic Substrate-Binding Proteins as Targets for Antimicrobial Therapies. Current Drug Targets (Print) , v. 13, p. 1400-1410, 2012.

• COUÑAGO, R. L. M. ; Miller, Corwin ; Davlieva, Milya ; Wilson, Corey ; White, Kristopher I. ; Wu, Gang ; Myers, Jeffrey&nbsp ; Wittung-Stafshede, Pernilla ; Shamoo, Yousif . Experimental Evolution of Adenylate Kinase Reveals Contrasting Strategies toward Protein Thermostability. Biophysical Journal (Print) , v. 99, p. 887-896, 2010.

• Couñago, Rafael Miguez ; Fleming, Stephen B. ; Mercer, Andrew A. ; Krause, Kurt L. . Crystallization and preliminary X-ray analysis of the chemokine-binding protein from orf virus ( ). Acta Crystallographica. Section F , v. 66, p. 819-823, 2010.

• Couñago, Rafael M ; Davlieva, Milya ; Strych, Ulrich ; Hill, Ryan E ; Krause, Kurt L . Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames). BMC Structural Biology (Online) , v. 9, p. 53, 2009.

• Romanel, Elisson A. C. ; Schrago, Carlos G. ; Couñago, Rafael M. ; Russo, Claudia A. M. ; Alves-Ferreira, Márcio . Evolution of the B3 DNA Binding Superfamily: New Insights into REM Family Gene Diversification. Plos One , v. 4, p. e5791, 2009.

• Counago, R. ; Wilson, C. J. ; Pena, M. I. ; Wittung-Stafshede, P. ; Shamoo, Y. . An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability-activity trade-offs. Protein Engineering, Design & Selection (Print) , v. 21, p. 19-27, 2007.

• Couñago, Rafael ; Chen, Stephen ; Shamoo, Yousif . In Vivo Molecular Evolution Reveals Biophysical Origins of Organismal Fitness. Molecular Cell , v. 22, p. 441-449, 2006.

• Couñago, Rafael ; Shamoo, Yousif . Gene replacement of adenylate kinase in the gram-positive thermophile Geobacillus stearothermophilus disrupts adenine nucleotide homeostasis and reduces cell viability. Extremophiles (Tokyo. Print) , v. 9, p. 135-144, 2005.

• McEwan, AG ; DJOKO, K. Y. ; CHEN, N. H. ; COUÑAGO, R. L. M. ; KIDD, S. P. ; POTTER, A. J. ; JENNINGS, M. P. . Novel Bacterial MerR-Like Regulators: Their Role in the Response to Carbonyl and Nitrosative Stress. In: Robert K. Poole. (Org.). Advances in Microbial Physiology. 1ed.London: ACADEMIC PRESS, 2011, v. 58, p. 1-22.

• DUTRA, LUIZ A. ; DE SOUZA GAMA, FERNANDO H. ; SERAFIM, RICARDO A. M. ; DOS REIS, CAIO V. ; VASCONCELOS, STANLEY N. S. ; SANTIAGO, ANDRÉ DA SILVA ; TAKARADA, JÉSSICA E. ; DI PILLO, FÚLVIA ; AZEVEDO, H. ; MASCARELLO, ALESSANDRA ; GUIMARÃES, CRISTIANO R. W. ; Counago, R.M. . Exploring pyridine-based ligands against human vaccinia-related kinases 1 and 2. In: 9th Brazilian Symposium on Medicinal Chemistry - BrazMedChem, 2019, Pirenópolis. 9th Brazilian Symposium on Medicinal Chemistry - BrazMedChem, 2019. v. 1. p. 1-1.

• MEIRELLES, M. A. ; Couñago, Rafael M. ; PILLI, R. A. . Efforts towards macrocyclic dehydrofolate reductase inhibitors. In: 9th Brazilian Symposium on Medicinal Chemistry - BrazMedChem, 2019, Pirenópolis. 9th Brazilian Symposium on Medicinal Chemistry - BrazMedChem, 2019. v. 1. p. 1-1.

• RIBOLDI, G.P. ; VIEIRA, A. ; SANTANA, D. P. ; MCINTOSH, F. ; SILVA, R. C. ; DREWES, C. C. ; SANTHAKUMAR, S. ; BEHR, M. A. ; WALPOLE, C. ; PILLI, R. A. ; BARREIRO, G. ; Couñago, Rafael M. . An Open Science, Medicinal Chemistry Program to Develop New Therapeutics Against Non-Tuberculous Mycobacteria. In: 9th Brazilian Symposium on Medicinal Chemistry - BrazMedChem, 2019, Pirenópolis. 9th Brazilian Symposium on Medicinal Chemistry - BrazMedChem, 2019. v. 1. p. 1-1.

• RAMOS, PRISCILA ZONZINI ; CATTA-PRETA, C.M.C ; MOTTRAM, J.C. ; COUÑAGO, R. M. . A CHEMICAL BIOLOGY PLATFORM TO VALIDATE GENETICALLY-ESSENTIAL PROTEIN KINASES AS DRUG TARGETS IN LEISHMANIA. In: XXXV Annual Meeting of the Brazilian Society of Protozoology, 2019, Caxambu. XXXV Annual Meeting of the Brazilian Society of Protozoology, 2019. v. 1. p. 1-1.

• CATTA-PRETA, C.M.C ; RAMOS, PRISCILA ZONZINI ; VASCONCELOS, STANLEY N. S. ; FANTI, R.C. ; RIBOLDI, G.P. ; MORETTI, N.S. ; VAULLAUD, J. ; ROBERS, M. ; COUÑAGO, R. M. . Detecting compound target engagement in living Leishmania cells. In: XXXV Annual Meeting of the Brazilian Society of Protozoology, 2019, Caxambu. XXXV Annual Meeting of the Brazilian Society of Protozoology, 2019. v. 1. p. 1-1.

• MARCELINO, T. P. ; FALA, ANGELA M. ; COUÑAGO, R. M. ; MALVEZZI, A. M. ; MASSIRER, KATLIN B. ; SCHENKMAN, S. . Characterization of the Trypanosoma cruzi TcK2, an eIF2 protein kinase as a possible drug target. In: XXXV Annual Meeting of the Brazilian Society of Protozoology, 2019, Caxambu. XXXV Annual Meeting of the Brazilian Society of Protozoology, 2019. v. 1. p. 1-1.

• DOS REIS, CAIO V. ; BARREIRO, G. ; DA SILVA SANTIAGO, ANDRÉ ; LAMMOGLIA, J. ; DIAS, L.C. ; KRATZ, J. M. ; COUÑAGO, R. M. . An Open Science Structure-based Drug Discovery Programme targeting Leishmania aminoacyl tRNA Synthetases. In: XXXV Annual Meeting of the Brazilian Society of Protozoology, 2019, Caxambu. XXXV Annual Meeting of the Brazilian Society of Protozoology, 2019. v. 1. p. 1-1.

• COUÑAGO, R. M. ; PROFETA, GERSON S. ; SANTIAGO, ANDRÉ DA S. ; DOS REIS, CAIO V. ; GODOI, PAULO ; FALA, ANGELA M. ; WELLS, CARROW ; SARTORI, ROGER ; SALMAZO, A. P. T. ; RAMOS, PRISCILA ZONZINI ; MASSIRER, KATLIN B. ; ELKINS, JONATHAN M. ; DREWRY, D. H. ; GILEADI, OPHER . Identification of Tool Compounds to Study The Cellular Roles of Ca2+/Cam-Dependent Protein Kinases Kinases (Camkk). In: Advances in Metabolic Communication, 2019, Rio de Janeiro. Advances in Metabolic Communication, 2019. v. 1. p. 1-1.

• COUÑAGO, R. M. ; AZEVEDO, HATYLAS ; GODOI, PAULO H. C. ; SALMAZO, ANITA P. T. ; MASCARELLO, ALESSANDRA ; DE SOUZA GAMA, FERNANDO H. ; MASSIRER, KATLIN B. ; ARRUDA, PAULO ; GUIMARÃES, CRISTIANO R. W. ; GILEADI, OPHER . Development of tool compounds to investigate the cellular function of human protein kinase VRK1. In: 8 th Brazilian Symposium on Medicinal Chemistry, 2016, Búzios. 8 th Brazilian Symposium on Medicinal Chemistry, 2016. v. 1. p. 1-1.

• COUNAGO, R. M. ; WEEN, M. P. ; BEGG, S. L. ; BAJAJ, M. ; ZUEGG, J. ; O?MARA, M. L. ; COOPER, M. A. ; McEwan, AG ; PATON, J. C. ; KOBE, B. ; MCDEVITT, C. A. . Imperfect coordination chemistry facilitates metal ion release in the Psa permease. In: Latin American Summit Meeting on Biological Crystallography and Complementary Methods, 2014, Campinas. Latin American Summit Meeting on Biological Crystallography and Complementary Methods, 2014.

• Couñago, Rafael M. ; KNAPP, K. ; Krause, Kurt L ; Fleming, Stephen B. ; Mercer, Andrew A. . Update on the chemokine binding protein from orf virus. In: Joint Meeting of the Asian Crystallographic Association (AsCA), Society of Crystallographers in Australia and New Zealand (SCANZ), CRYSTAL 28, 2012, Adelaide. Joint Meeting of the Asian Crystallographic Association (AsCA), Society of Crystallographers in Australia and New Zealand (SCANZ), CRYSTAL 28, 2012.

• Chang, CW ; Couñago, Rafael M. ; WILLIAMS, S. J. ; Bodén, M ; KOBE, B. . Crystal Structure of Rice Importin-a and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. In: Joint Meeting of the Asian Crystallographic Association (AsCA), Society of Crystallographers in Australia and New Zealand (SCANZ), CRYSTAL 28, 2012, Adelaide. Joint Meeting of the Asian Crystallographic Association (AsCA), Society of Crystallographers in Australia and New Zealand (SCANZ), CRYSTAL 28, 2012.

• Couñago, Rafael M. ; WEEN, M. P. ; BAJAJ, M. ; ZUEGG, J. ; COOPER, M. A. ; McEwan, AG ; PATON, J. C. ; KOBE, B. . Letting it go is hard to do ? conformational changes during metal binding and release in pneumococcal surface antigen A (PsaA). In: Joint Meeting of the Asian Crystallographic Association (AsCA), Society of Crystallographers in Australia and New Zealand (SCANZ), CRYSTAL 28, 2012, Adelaide. Joint Meeting of the Asian Crystallographic Association (AsCA), Society of Crystallographers in Australia and New Zealand (SCANZ), CRYSTAL 28, 2012.

• Couñago, Rafael M ; CHEN, N. H. ; DJOKO, K. Y. ; McEwan, AG ; KOBE, B. . Structural and biochemical characterisation of the Neisserial EstD. In: BacPath 11: Molecular Analysis of Bacterial Pathogens, 2011, Wyong. BacPath 11: Molecular Analysis of Bacterial Pathogens, 2011.

• Couñago, Rafael M ; Chen, Stephen ; DJOKO, K. Y. ; McEwan, AG ; KOBE, B. . The structure of a bacterial esterase essential for NO-stress response. In: XXII Congress and General Assembly of the International Union of Crystallography, 2011, Madrid. XXII Congress and General Assembly of the International Union of Crystallography, 2011.

• Couñago, Rafael Miguez ; CHEN, N. H. ; DJOKO, K. Y. ; KOBE, B. ; McEwan, AG . The structure of the Neisserial Esterase D. In: 36th Lorne Conference on Protein Structure and Function, 2011, Lorne. 36th Lorne Conference on Protein Structure and Function, 2011.

• Couñago, Rafael ; Wilson, C. J. ; Wittung-Stafshede, P. ; Shamoo, Y. . Evolution from a thermodynamics standpoint: Biophysical characterization of adenylate kinase mutants isolated from an in vivo directed evolution experiment. In: Biophysical Society - 49th Annual Meeting, 2006, Long Beach, CA. 48th Annual Meeting of the Biophysical Society, 2006.

• Couñago, Rafael Miguez ; Shamoo, Y. . In vivo molecular evolution reveals biophysical origins of organismal fitness. In: Annual Meeting for the Society for Molecular Biology and Evolution, 2006, Tempe. Genomes, Evolution, and Bioinformatics, 2006.

• Counago, R. ; Shamoo, Y. . Evolution of protein thermostability in a coffee pot. In: 8th Structural Biology Symposium, 2003, Galveston, TX. 8th Structural Biology Symposium, 2003.

• Couñago, Rafael ; Shamoo, Yousif . In vivo selection of thermostable B. subtilis adenylate kinase mutants: molecular evolution in a continuous growth chemostat.. In: W.M Keck Center for Computational and Structural biology, 2003, Clear Lake, TX. 2003 Annual Research Conference, 2003.

• Couñago, Rafael ; PERRY, R. ; Shamoo, Yousif . Structural studies of two enzymes involved in the production of the antibiotic valanimycin. In: Annual Meeting for the American Crystallographic Association, 2002, San Antonio, TX. 2002 Annual Meeting, 2002.

• Couñago, Rafael ; Shamoo, Yousif . An in vivo evolution strategy to study protein thermostability. In: 2002 Bioinformatics Symposium, 2002, Houston, TX. 2002 Bioinformatics Symposium, 2002.

• Gomes, LL ; Couñago, Rafael M ; Margis, R . Mutagênese sítio dirigida na cistatina do arroz: clonagem, expressão e purificação de um possível inibidor para a proteinase viral do GFLV. In: XX Jornada de Iniciação Científica da UFRJ, 1998, Rio de Janeiro. XX Jornada de Iniciação Científica da UFRJ, 1998.

• Reis, EM ; Couñago, Rafael M ; Margis, R . Clonagem das cistatinas de milho e arroz em vetor binário e produção de plantas transgênicas. In: XXVI Reunião da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1997, Caxambú. XXVI Reunião da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1997.

• Gomes, LL ; Couñago, Rafael M ; Margis, R . Localização celular e purificação da proteinase do GFLV produzida em células de E. coli. In: XIX Jornada de Iniciação Científica da UFRJ, 1997, Rio de Janeiro. XIX Jornada de Iniciação Científica da UFRJ, 1997.

• Couñago, Rafael M ; Reis, EM ; Margis, R . Purificação da protease do Grapevine Fanleaf Virus expressa em E. coli. In: XXVI Reunião da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1997, Caxambú. XXVI Reunião da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1997.

• Reis, EM ; Couñago, Rafael M ; Margis, R . Clonagem e Expressão das cistatinas de milho e arroz em um sistema heterólogo de E. coli. In: XXV Reunião da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1996, Caxambú. XXV Reunião da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1996.

• Couñago, Rafael M ; Margis, R . Clonagem e expressão simultânea da fitocistatina do arroz e da proteinase viral do GFLV em células de E. coli. In: XVIII Jornada de Iniciação Científica da UFRJ, 1996, Rio de Janeiro. XVIII Jornada de Iniciação Científica da UFRJ, 1996.

• Reis, EM ; Couñago, Rafael M ; Margis, R . Processamento de um precurssor polipeptídico pela proteinase do GFLV em um sistema heterólogo de E. coli. In: XVII Congresso Nacional de Genética, 1996, Caxambú. XVII Congresso Nacional de Genética, 1996.

• Counago, R.M. . Developing novel tools to guide the discovery of new cell-permeable, on-target anti-infective compounds.. 2021. (Apresentação de Trabalho/Congresso).

• REIS, C. V. ; SILVA, R. C. ; SANT´ANA, D. P. ; GELVES, L. G. V. ; MOWBRAY, C. E. ; KRATZ, J. M. ; BARREIRO, G. ; COUÑAGO, R. M. . Open-Science Structure-Based Drug Discovery Leishmania infantum Aminoacyl tRNA Synthetases. 2019. (Apresentação de Trabalho/Simpósio).

• PROFETA, G. S. ; DA SILVA SANTIAGO, ANDRÉ ; DOS REIS, CAIO V. ; GODOI, PAULO ; FALA, ANGELA M. ; WELLS, CARROW ; SARTORI, ROGER ; SALMAZO, ANITA P. T. ; RAMOS, PRISCILA Z. ; MASSIRER, KATLIN B. ; ELKINS, JONATHAN M. ; DREWRY, D. H. ; GILEADI, OPHER ; COUÑAGO, R. M. . IDENTIFICATION OF TOOL COMPOUNDS TO STUDY THE CELLULAR ROLES OF Ca2+/CaM-DEPENDENT PROTEIN KINASES KINASES (CaMKK). 2019. (Apresentação de Trabalho/Conferência ou palestra).

• CATTA-PRETA, C.M.C ; RAMOS, PRISCILA ZONZINI ; VASCONCELOS, STANLEY N. S. ; FANTI, R.C. ; RIBOLDI, G.P. ; MORETTI, N.S. ; VAULLAUD, J. ; ROBERS, M. ; COUÑAGO, R. M. . Detecting compound target engagement in living Leishmania cells. 2019. (Apresentação de Trabalho/Congresso).

• RAMOS, PRISCILA ZONZINI ; CATTA-PRETA, C.M.C ; MOTTRAM, J.C. ; COUÑAGO, R. M. . A CHEMICAL BIOLOGY PLATFORM TO VALIDATE GENETICALLY-ESSENTIAL PROTEIN KINASES AS DRUG TARGETS IN LEISHMANIA. 2019. (Apresentação de Trabalho/Congresso).

• REIS, C. V. ; BARREIRO, G. ; DA SILVA, R.C. ; LAMMOGLIA, J. ; DIAS, L.C. ; KRATZ, J. M. ; COUÑAGO, R. M. . An Open Science Structure-based Drug Discovery Programme targeting Leishmania aminoacyl tRNA Synthetases. 2019. (Apresentação de Trabalho/Congresso).

• MARCELINO, T. P. ; FALA, ANGELA M. ; COUÑAGO, R. M. ; MALVEZZI, A. M. ; MASSIRER, KATLIN B. ; SCHENKMAN, S. . Characterization of the Trypanosoma cruzi TcK2, an eIF2 protein kinase as a possible drug target. 2019. (Apresentação de Trabalho/Congresso).

• RIBOLDI, G.P. ; VIEIRA, A. S. ; SANTANA, D. P. ; MCINTOSH, F. ; SILVA, R. C. ; DREWES, C. C. ; SANTHAKUMAR, S. ; BEHR, M. A. ; WALPOLE, C. ; PILLI, R. A. ; BARREIRO, G. ; COUÑAGO, R. M. . An Open Science, Medicinal Chemistry Program to Develop New Therapeutics Against Non-Tuberculous Mycobacteria. 2019. (Apresentação de Trabalho/Congresso).

• MEIRELLES, M. A. ; COUÑAGO, R. M. ; PILLI, R. A. . Efforts towards macrocyclic dihydrofolate reductase inhibitors. 2019. (Apresentação de Trabalho/Congresso).

• SEGRETTI, N. D. ; GODOI, PAULO ; SERAFIM, RICARDO A. M. ; AZEVEDO, H. ; MASCARELLO, A. ; COUÑAGO, R. M. ; GUIMARÃES, CRISTIANO R. W. . Structure-based design and synthesis of new benzothiophene derivatives as potent PRPF4 kinase inhibitors. 2019. (Apresentação de Trabalho/Congresso).

• DUTRA, LUIZ A. ; GAMA, F. H. S. ; SERAFIM, RICARDO A. M. ; REIS, C. V. ; VASCONCELOS, STANLEY N. S. ; DA SILVA SANTIAGO, ANDRÉ ; TAKARADA, J. E. ; DI PILLO, FÚLVIA ; AZEVEDO, H. ; MASCARELLO, A. ; GUIMARAES, C. R. W. ; COUÑAGO, R. M. . Exploring pyridine-based ligands against human vaccinia-related kinases 1 and 2. 2019. (Apresentação de Trabalho/Congresso).

• COUÑAGO, R. M. . Structural Genomics Consortium: Enabling structure-based drug development for Emerging and Neglected Diseases in the Open. 2019. (Apresentação de Trabalho/Conferência ou palestra).

• COUÑAGO, RAFAEL M. . Identification and validation of novel therapeutic targets using chemical biology. 2018. (Apresentação de Trabalho/Congresso).

• COUÑAGO, R. M. . Right on Target! A Target Validation Pipeline for Neglected Tropical Diseases within the Structural Genomics Consortium site at UNICAMP. 2018. (Apresentação de Trabalho/Conferência ou palestra).

• COUNAGO, R. M. . The Structural Genomcis Consortium @ UNICAMP - Accelerating Discoveries Through Open Science. 2017. (Apresentação de Trabalho/Seminário).

• COUNAGO, R. M. . Using chemical probes to validate new therapeutic targets. 2017. (Apresentação de Trabalho/Seminário).

• Couñago, Rafael M. ; CHANG, CHIUNG-WEN ; WILLIAMS, S. J. ; BODEN, M. ; KOBE, BOSTJAN . CLASSICAL NUCLEAR IMPORT PATHWAY IN PLANTS - STRUCTURAL BASIS FOR THE INTERACTION BETWEEN RICE IMPORTIN-α; AND PLANT- SPECIFIC NUCLEAR LOCALISATION SEQUENCES. 2016. (Apresentação de Trabalho/Conferência ou palestra).

• Couñago, Rafael Miguez ; AZEVEDO, H. ; GODOI, P. H. ; SALMAZO, A. ; MASCARELLO, A. ; GAMA, F. H. S. ; MASSIRER, K. B. ; ARRUDA, P. ; GUIMARAES, C. R. W. ; GILEADI, O. . Development of tool compounds to investigate the cellular function of human protein kinase VRK1. 2016. (Apresentação de Trabalho/Simpósio).

• Couñago, Rafael M . The Structural Genomics Consortium at UNICAMP - Supporting Drug Development Through Open-Access Research. 2016. (Apresentação de Trabalho/Simpósio).

• COUÑAGO, R. M. . Planejamento de ligantes baseados na estrutura tridimensional da proteína-alvo. 2016. (Apresentação de Trabalho/Simpósio).

• COUÑAGO, R. M. . An introduction to target-based drug discovery. 2016. (Apresentação de Trabalho/Simpósio).

• Counago, R. ; CHEN, N. H. ; Karrera Y. Djoko ; McEwan, AG ; KOBE, B. . The structure of a bacterial esterase essential for NO-stress response.. 2011. (Apresentação de Trabalho/Seminário).

• Counago, R. ; CHEN, N. H. ; DJOKO, K. Y. ; McEwan, AG ; KOBE, B. . The structure of a bacterial esterase essential for NO-stress response.. 2011. (Apresentação de Trabalho/Congresso).

• Counago, R. ; CHEN, N. H. ; DJOKO, K. Y. ; McEwan, AG ; KOBE, B. . Structural and biochemical characterisation of the Neisserial EstD. 2011. (Apresentação de Trabalho/Conferência ou palestra).

• Counago, R. . Crystallography from down under: the structural basis for the broad specificity of poxviral chemokine binding protein. 2011. (Apresentação de Trabalho/Comunicação).

• Counago, R. ; CHEN, N. H. ; DJOKO, K. Y. ; McEwan, AG ; KOBE, B. . Structural and biochemical characterisation of the Neisserial EstD. 2011. (Apresentação de Trabalho/Simpósio).

• Counago, R. ; Davlieva, Milya ; Krause, Kurt L. . Structural characterization of alanine racemase from Bacillus anthracis.. 2009. (Apresentação de Trabalho/Congresso).

• Counago, R. ; Fleming, Stephen B. ; Mercer, Andrew A. ; Krause, Kurt L . Crystallization of the chemokine binding protein from orf virus.. 2009. (Apresentação de Trabalho/Simpósio).

• Counago, R. ; Davlieva, Milya ; Krause, Kurt L . Structural characterization of alanine racemase from Bacillus anthracis. 2009. (Apresentação de Trabalho/Simpósio).

• Counago, R. . Predicting protein adaptive evolution: what are we missing?. 2009. (Apresentação de Trabalho/Simpósio).

• Counago, R. . In vivo molecular evolution reveals biophysical origins of organismal fitness.. 2009. (Apresentação de Trabalho/Comunicação).

• Counago, R. . In vivo molecular evolution reveals biophysical origins of organismal fitness.. 2009. (Apresentação de Trabalho/Comunicação).

• Counago, R. . In vivo molecular evolution reveals biophysical origins of organismal fitness.. 2008. (Apresentação de Trabalho/Congresso).

• Couñago, Rafael ; Wilson, C. J. ; Wittung-Stafshede, P. ; Shamoo, Y. . Evolution from a thermodynamics standpoint: Biophysical characterization of adenylate kinase mutants isolated from an in vivo directed evolution experiment. 2006. (Apresentação de Trabalho/Congresso).

• Couñago, Rafael ; Shamoo, Yousif . In vivo selection of thermostable B. subtilis adenylate kinase mutants: molecular evolution in a continuous growth chemostat.. 2003. (Apresentação de Trabalho/Conferência ou palestra).

• Couñago, Rafael ; Shamoo, Yousif . Evolution of protein thermostability in a coffee pot. 2003. (Apresentação de Trabalho/Simpósio).

• Couñago, Rafael ; Shamoo, Y. ; PERRY, R. . Structural studies of two enzymes involved in the production of the antibiotic valanimycin. 2002. (Apresentação de Trabalho/Congresso).

• Couñago, Rafael ; Shamoo, Yousif . An in vivo evolution strategy to study protein thermostability. 2002. (Apresentação de Trabalho/Simpósio).

• Gomes, LL ; Counago, R. ; Margis, R . Mutagênese sítio dirigida na cistatina do arroz: clonagem, expressão e purificação de um possível inibidor para a proteinase viral do GFLV. 1998. (Apresentação de Trabalho/Congresso).

• Counago, R. ; Reis, EM ; Margis, R . Purificação da protease do Grapevine Fanleaf Virus expressa em E. coli. 1997. (Apresentação de Trabalho/Congresso).

• Reis, EM ; Counago, R. ; Margis, R . Clonagem das cistatinas de milho e arroz em vetor binário e produção de plantas transgênicas. 1997. (Apresentação de Trabalho/Congresso).

• Gomes, LL ; Pereira, A ; Counago, R. ; Margis, R . Localização celular e purificação da proteinase do GFLV produzida em células de E. coli. 1997. (Apresentação de Trabalho/Congresso).

• Reis, EM ; Counago, R. ; Margis, R . Clonagem e Expressão das cistatinas de milho e arroz em um sistema heterólogo de E. coli. 1996. (Apresentação de Trabalho/Congresso).

• Reis, EM ; Counago, R. ; da Silva, GG ; Margis, R . Processamento de um precurssor polipeptídico pela proteinase do GFLV em um sistema heterólogo de E. coli. 1996. (Apresentação de Trabalho/Congresso).

• Counago, R. ; Margis, R . Clonagem e expressão simultânea da fitocistatina do arroz e da proteinase viral do GFLV em células de E. coli. 1996. (Apresentação de Trabalho/Congresso).

• COUÑAGO, RAFAEL M. . From genes to drugs. 2016. (Curso de curta duração ministrado/Outra).

• COUÑAGO, RAFAEL M. . Planejamento de ligantes baseado na estrutura tridimensional da proteína-alvo. 2016. (Curso de curta duração ministrado/Outra).

• ARRUDA, P. ; BENGSTON, M. ; BRENAN, P. ; COUNAGO, R. M. ; GILEADI, O. ; GILEADI, C. ; GODOI, P. H. ; MASSIRER, K. B. ; REIS, M. B. C. ; RUELA-DE-SOUZA, R. R. ; SALMAZO, A. P. T. . From gene to drugs. 2015. (Curso de curta duração ministrado/Outra).

Projetos de pesquisa

• 2010 - Atual

  Pathogenesis, treatment and prevention of bacterial infectious diseases, Situação: Em andamento; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (10) / Especialização: (0) / Mestrado acadêmico: (0) / Mestrado profissional: (0) / Doutorado: (4) . , Integrantes: Rafael Lemos Miguez Couñago - Integrante / Alastair G. McEwan - Integrante / Bostjan Kobe - Coordenador., Financiador(es): The University of Queensland - Outra., Número de produções C, T & A: 10

Prêmios