Ariane Karla Cruz Gomes

Pós-doutorado

Formação complementar

Idiomas

Áreas de atuação

Participação em eventos

Orientou

Produções bibliográficas

• GOMES, A. C. ; BARANIAK, I. A. ; LANKINA, A. ; MOULDER, Z. ; HOLENYA, P. ; ATKINSON, C. ; TANG, G. ; MAHUNGU, T. ; KERN, F. ; GRIFFITHS, P. D. ; REEVES, M. B. . The cytomegalovirus gB/MF59 vaccine candidate induces antibodies against an antigenic domain controlling cell-to-cell spread. Nature Communications , v. 14, p. 1041, 2023.

• FORREST, CALUM ; GOMES, ARIANE ; REEVES, MATTHEW ; MALE, VICTORIA . NK Cell Memory to Cytomegalovirus: Implications for Vaccine Development. Vaccines , v. 8, p. 394, 2020.

• MOHSEN, MONA O. ; VOGEL, MONIQUE ; RIETHER, CARSTEN ; MULLER, JULIUS ; SALATINO, SILVIA ; TERNETTE, NICOLA ; Gomes, Ariane C. ; CABRAL-MIRANDA, GUSTAVO ; EL-TURABI, AADIL ; RUEDL, CHRISTIANE ; KUNDIG, THOMAS M. ; DERMIME, SAID ; KNUTH, ALEXANDER ; SPEISER, DANIEL E. ; BACHMANN, MARTIN F. . Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine. Frontiers in Immunology , v. 10, p. 1050, 2019.

• C. Gomes, Ariane ; ROESTI, E. S. ; EL-TURABI, AADIL ; BACHMANN, MARTIN F. . Type of RNA Packed in VLPs Impacts IgG Class Switching-Implications for an Influenza Vaccine Design. Vaccines , v. 7, p. 47, 2019.

• Gomes, Ariane C. ; GRIFFITHS, PAUL D. ; REEVES, MATTHEW B. . The Humoral Immune Response Against the gB Vaccine: Lessons Learnt from Protection in Solid Organ Transplantation. Vaccines , v. 7, p. 67, 2019.

• Gomes, Ariane C. ; MOHSEN, MONA O. ; MUELLER, JULIUS E. ; LEORATTI, FABIANA M. S. ; CABRAL-MIRANDA, GUSTAVO ; BACHMANN, MARTIN F. . Early Transcriptional Signature in Dendritic Cells and the Induction of Protective T Cell Responses Upon Immunization With VLPs Containing TLR Ligands-A Role for CCL2. Frontiers in Immunology , v. 10, p. 1679, 2019.

• BARANIAK, ILONA ; Gomes, Ariane C. ; SODI, ISABELLA ; LANGSTONE, TOBY ; ROTHWELL, EMILY ; ATKINSON, CLAIRE ; PICHON, SYLVIE ; PIRAS-DOUCE, FABIENNE ; GRIFFITHS, PAUL D. ; REEVES, MATTHEW B. . Seronegative patients vaccinated with cytomegalovirus gB-MF59 vaccine have evidence of neutralising antibody responses against gB early post-transplantation. EBIOMEDICINE , v. 50, p. 45-54, 2019.

• MOHSEN, MONA ; GOMES, ARIANE ; VOGEL, MONIQUE ; BACHMANN, MARTIN . Interaction of Viral Capsid-Derived Virus-Like Particles (VLPs) with the Innate Immune System. Vaccines , v. 6, p. 37, 2018.

• GOMES, ARIANE ; MOHSEN, MONA ; BACHMANN, MARTIN . Harnessing Nanoparticles for Immunomodulation and Vaccines. Vaccines , v. 5, p. 6, 2017.

• Gomes, Ariane C. ; FLACE, ANNA ; SAUDAN, PHILIPPE ; ZABEL, FRANZISKA ; CABRAL-MIRANDA, GUSTAVO ; TURABI, AADIL EL ; MANOLOVA, VANIA ; BACHMANN, MARTIN F. . Adjusted Particle Size Eliminates the Need of Linkage of Antigen and Adjuvants for Appropriated T Cell Responses in Virus-Like Particle-Based Vaccines. Frontiers in Immunology (Online) , v. 8, p. 266, 2017.

• CABRAL-MIRANDA, GUSTAVO ; HEATH, MATTHEW ; MOHSEN, MONA ; GOMES, ARIANE ; ENGEROFF, PAUL ; FLAXMAN, AMY ; LEORATTI, FABIANA ; EL-TURABI, AADIL ; REYES-SANDOVAL, ARTURO ; SKINNER, MURRAY ; KRAMER, MATTHIAS ; BACHMANN, MARTIN . Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax. Vaccines , v. 5, p. 10, 2017.

• MOHSEN, MONA O. ; Gomes, Ariane C. ; CABRAL-MIRANDA, GUSTAVO ; KRUEGER, CAROLINE C. ; LEORATTI, FABIANA MS ; STEIN, JENS V. ; BACHMANN, MARTIN F. . Delivering adjuvants and antigens in separate nanoparticles eliminates the need of physical linkage for effective vaccination. JOURNAL OF CONTROLLED RELEASE , v. 251, p. 92-100, 2017.

• DOUCET, MARIKA ; EL-TURABI, AADIL ; ZABEL, FRANZISKA ; HUNN, BENJAMIN H.M. ; BENGOA-VERGNIORY, NORA ; CIOROCH, MILENA ; RAMM, MAURICIO ; SMITH, AMY M. ; Gomes, Ariane Cruz ; CABRAL DE MIRANDA, GUSTAVO ; WADE-MARTINS, RICHARD ; BACHMANN, MARTIN F. . Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles. PLoS One , v. 12, p. e0181844, 2017.

• AMARAL, SYLVIA S ; OLIVEIRA, ANDRÉ G ; MARQUES, PEDRO E ; QUINTÃO, JAYANE L ; PIRES, DANIELE A ; RESENDE, RODRIGO R ; SOUSA, BRUNA R ; MELGAÇO, JULIANA G ; PINTO, MARCELO A ; RUSSO, REMO C ; GOMES, ARIANE K ; ANDRADE, LIDIA M ; ZANIN, RAFAEL F ; PEREIRA, RAFAELA VAZ ; BONORINO, CRISTINA ; SORIANI, FREDERICO M ; LIMA, CRISTIANO XAVIER ; CARA, DENISE C ; TEIXEIRA, MAURO M ; LEITE, MARIA F . Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity. CELL COMMUN SIGNAL , v. 11, p. 10, 2013.

• GUABIRABA, RODRIGO ; RUSSO, REMO C. ; COELHO, AMANDA M. ; FERREIRA, MÔNICA A. N. D. ; LOPES, GABRIEL A. O. ; GOMES, ARIANE K. C. ; ANDRADE, SILVIA P. ; BARCELOS, LUCIOLA S. ; TEIXEIRA, MAURO M. . Blockade of cannabinoid receptors reduces inflammation, leukocyte accumulation and neovascularization in a model of sponge-induced inflammatory angiogenesis. Inflammation Research (Printed ed.) , v. 62, p. 811-821, 2013.

• DUTRA, M. S. ; BELA, S. R. ; PEIXOTO-RANGEL, A. L. ; FAKIOLA, M. ; CRUZ, A. G. ; GAZZINELLI, A. ; QUITES, H. F. ; BAHIA-OLIVEIRA, L. M. G. ; PEIXE, R. G. ; CAMPOS, W. R. ; HIGINO-ROCHA, A. C. ; MILLER, N. E. ; BLACKWELL, J. M. ; ANTONELLI, L. R. ; GAZZINELLI, R. T. . Association of a NOD2 Gene Polymorphism and T-Helper 17 Cells With Presumed Ocular Toxoplasmosis. JOURNAL OF INFECTIOUS DISEASES , v. 207, p. 152-163, 2012.

• GOMES, A. K. C. ; GARCIA, C. C. ; LOPES, GABRIEL A. O. ; RUSSO, REMO C ; TEIXEIRA, MAURO M . DEFICIENCY OF THE ATYPICAL CHEMOKINE RECEPTOR D6 PROTECTS MICE FROM LETHALITY INDUCED BY INFLUENZA A VIRUS (IAV) INFECTION THROUGH INCREASED LYMPHOCYTE INFLUX AND ATTENUATED VIRAL BURDEN. 2013. (Apresentação de Trabalho/Congresso).

• GOMES, A. K. C. ; DUTRA, M. ; BELA, S. R. ; OREFICE, ; GAZZINELI, R. T. . Associação entre os níveis de imunoglobulinas e os diferentes tipos de lesão ocular decorrentes da infecção do Toxoplasma gondii. 2010. (Apresentação de Trabalho/Congresso).

Projetos de pesquisa

• 2011 - Atual

  Papel da Bradicinina na inflamação e fibrose pulmonar induzida por bleomicina em animais deficientes para os receptores B1R e B2R ou tratados com antagonistas, Descrição: Estudo do papel da Bradicinina na inflamação e fibrose pulmonar induzida por bleomicina em animais deficientes para os receptores B1R e B2R ou tratados com antagonistas. , Situação: Desativado; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (3) / Doutorado: (1) . , Integrantes: Ariane Karla Cruz Gomes - Integrante / remo de castro russo - Coordenador.

• 2011 - Atual

  Deficiency of the decoy receptor D6 protects mice from lethality induced by Influenza A(IAV) infection, Descrição: Influenza A virus (IAV) infection has major relevance in worldwide epidemic episodes causing several cases of respiratory diseases and the severe pandemic H1N1. Once infected, the immune response is recruited to overcome pathogen proliferation, but in many cases an unbalanced immune response is responsible for intense tissue damage sometimes worse than the infection itself. The scavenger receptor D6, a seven transmembrane receptor that selectively bind and targets β-chemokines (CC motif) for degradation, is constantly reported as a pro-resolutive receptor with protective role on many diseases by reducing the concentration of inflammatory mediators. The role of D6 receptor is evaluated in IAV infection and our findings demonstrate an atypical effect of D6 depletion, which resulted in protective effect.. , Situação: Desativado; Natureza: Pesquisa. , Alunos envolvidos: Graduação: (3) / Doutorado: (4) . , Integrantes: Ariane Karla Cruz Gomes - Integrante / RUSSO, REMO C - Coordenador / TEIXEIRA, MAURO M - Integrante / Cristiana Couto Garcia - Integrante.

Prêmios