Lucas Vieira dos Santos

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Áreas de atuação

Organização de eventos

Participação em eventos

Produções bibliográficas

• MONTEIRO, FERNANDO S. M. ; SCHUTZ, FABIO A. ; MORBECK, IGOR A. P. ; BASTOS, DIOGO A. ; DE PADUA, FERNANDO V. ; COSTA, LEONARDO A. G. A. ; MAIA, MANUEL C. ; RINCK JR, JOSE A. ; ZEQUI, STENIO DE CASSIO ; DA TRINDADE, KARINE M. ; ALFER JR, WLADIMIR ; NAHAS, WILLIAM C. ; DOS SANTOS, LUCAS V. ; FERRIGNO, ROBSON ; DA ROSA, DIOGO A. R. ; SADE, JUAN P. ; ORLANDI, FRANCISCO J. ; DE OLIVEIRA, FERNANDO N. G. ; SOARES, ANDREY . Consensus on Treatment and Follow-Up for Biochemical Recurrence in Castration-Sensitive Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries. Jco Global Oncology , v. 1, p. 538-544, 2021.

• MALUF, FERNANDO COTAIT ; PEREIRA, FELIPE MORAES TOLEDO ; SILVA, ADRIANO GONÇALVES ; DETTINO, ALDO LOURENÇO ABBADE ; CARDOSO, ANA PAULA GARCIA ; SASSE, ANDRÉ SEEKE ; SOARES, ANDREY ; KANN, ARIEL GALAPO ; HERCHENHORN, DANIEL ; JARDIM, DENIS LEONARDO FONTES ; CORTÉS, DIEGO EMILIO LOPERA ; KATER, FÁBIO ROBERTO ; MORBECK, IGOR A. PROTZNER ; REOLON, JOÃO FRANCISCO NAVARRO ; RINCK JR, JOSÉ AUGUSTO ; ZARBÁ, JUAN JOSE ; SADE, JUAN PABLO ; DA TRINDADE, KARINE MARTINS ; COSTA, LEONARDO ATEM G. A. ; DOS SANTOS, LUCAS V. ; MAIA, MANUEL CAITANO ; SIQUEIRA, MARIANA BRUNO ; GILLESSEN, SILKE . Consensus on the Treatment and Follow-Up for Metastatic Castration-Resistant Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries (PCCCDC). Jco Global Oncology , v. 1, p. 559-571, 2021.

• DOS SANTOS, LUCAS V. ; ABRAHÃO, CARINA M. ; WILLIAM, WILLIAM N. . Overcoming Resistance to Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinomas. FRONTIERS IN ONCOLOGY , v. 11, p. 596290, 2021.

• BRAGAGNOLI, ARINILDA CAMPOS ; ARAUJO, RAPHAEL L. C. ; FERRAZ, MAURICIO WAGNER ; dos Santos, Lucas Vieira ; ABDALLA, KATHIA CRISTINA ; COMAR, FABIANA ; SANTOS, FLORINDA ALMEIDA ; OLIVEIRA, MARCO ANTONIO ; CARVALHEIRA, JOSÉ BARRETO CAMPELLO ; CÁRCANO, FLÁVIO MAVIGNER ; da Silveira Nogueira Lima, João Paulo . Metformin plus lrinotecan in patients with refractory colorectal cancer: a phase 2 clinical trial. BRITISH JOURNAL OF CANCER , v. 124, p. 1072-1078, 2021.

• ALBUQUERQUE, C ; DEBIASI, M ; WERUTSKY, G ; UEMA, D ; CRONENBERGER, E ; CORDEIRO DE LIMA, VC ; DE SANT'ANA, RO ; BINES, J ; SANTI, PX ; GOÉS, RS ; LIEDKE, P ; BATISTA, MLM ; DYBAL, V ; NERÓN, YV ; BEATO, CA ; BORGES, G ; GIACOMAZZI, J ; DOS SANTOS, LV ; ISMAEL, G ; ROSA, DD ; AZAMBUJA, A ; ANDRADE, D ; MARTINEZ-MESA, J ; ZAFFARONI, F ; BARRIOS, CH . Abstract P1-17-10: Survival outcomes related to health care coverage in breast cancer patients with brain metastases in Brazil: A sub-analysis from the LACOG-0312 study. CANCER RESEARCH , v. 78, p. P1-17-10-P1-17-10, 2018.

• WERUTSKY, G ; ZAFFARONI, F ; UEMA, D ; CRONENBERGER, E ; CORDEIRO DE LIMA, VC ; DE SANT'ANA, RO ; BINES, J ; SANTI, PX ; GOÉS, RS ; LIEDKE, P ; BATISTA, MLM ; DYBAL, V ; NERÓN, YV ; BEATO, CA ; BORGES, G ; GIACOMAZZI, J ; DOS SANTOS, LV ; ISMAEL, G ; ROSA, DD ; AZAMBUJA, A ; ANDRADE, D ; MARTINEZ-MESA, J ; DEBIASI, M ; BARRIOS, CH . Abstract P4-10-17: Survival outcomes related to health care coverage in metastatic breast cancer in Brazil: A sub-analysis from the LACOG-0312 study. CANCER RESEARCH , v. 78, p. P4-10-17-P4-10-17, 2018.

• MURO, KEI ; CHO, JAE YONG ; BODOKY, GYORGY ; GOSWAMI, CHANCHAL ; CHAO, YEE ; dos Santos, Lucas V ; SHIMADA, YASUHIRO ; TOPUZOV, ELDAR ; VAN CUTSEM, ERIC ; TABERNERO, JOSEP ; ZALCBERG, JOHN ; CHAU, IAN ; CASCINU, STEFANO ; CHENG, REBECCA ; HSU, YANZHI ; EMIG, MICHAEL ; ORLANDO, MAURO ; FUCHS, CHARLES . Age does not influence efficacy of ramucirumab in advanced gastric cancer: Subgroup analyses of REGARD and RAINBOW. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY , v. in pre, p. in press, 2018.

• BARRIOS, CH ; UEMA, D ; CRONENBERGER, E ; LIMA, V ; BINES, J ; DE SANT'ANA, RO ; BATISTA, ML ; DYBAL, V ; LIEDKE, P ; BEATO, C ; NERÓN, YV ; GIACOMAZZI, J ; dos Santos, L ; ISMAEL, G ; AZAMBUJA, A ; ANDRADE, D ; ROSA, DD ; BORGES, G ; MANO, M ; MARTINEZ-MESA, J ; ZAFFARONI, F ; WERUTSKY, G . Abstract P6-16-04: Real World data and patterns of care of metastatic breast cancer (MBC) in Brazil: First results of LACOG 0312 retrospective study. CANCER RESEARCH , v. 77, p. P6-16-04-P6-16-04, 2017.

• dos Santos, Lucas Vieira ; VEIGA FARIA, THAISSA MARIA ; LIMA, ANDRE BACELLAR COSTA ; ABDALLA, KATHIA CRISTINA ; DE MORAES, EDUARDO DIAS ; CRUZ, MARCELO ROCHA ; LIMA, JOAO PAULO . Timing of adjuvant chemotherapy in colorectal cancer. Colorectal Disease (Print) , v. 18, p. 871-876, 2016.

• Dos Santos LV ; LESSA, M. A. O. ; LIMA, J. P. S. N. ; HAALAND, B. ; LOPES, G. L. . Curative-Intent Surgery for Pancreatic Tumors: A Review of Procedures From the Brazilian National Health System. Journal of Global Oncology , v. 1, p. 1, 2016.

• KIM, WOO-HO ; GOMEZ-IZQUIERDO, LOURDES ; VILARDELL, FELIP ; CHU, KENT-MAN ; SOUCY, GENEVIÈVE ; DOS SANTOS, LUCAS V. ; MONGES, GENEVIÈVE ; VIALE, GIUSEPPE ; BRITO, MARIA JOSÉ ; OSBORNE, STUART ; NOÉ, JOHANNES ; DU, XIANG . HER2 Status in Gastric and Gastroesophageal Junction Cancer. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY , v. 26, p. 239-245, 2016.

• dos Santos, Lucas Vieira ; CRUZ, MARCELO ROCHA ; LIMA LOPES, GILBERTO DE ; LIMA, JOAO PAULO DA SILVEIRA NOGUEIRA . VEGF-A levels in bevacizumab-treated breast cancer patients: a systematic review and meta-analysis. Breast Cancer Research and Treatment , v. 151, p. 481-489, 2015.

• METON-VIEIRA, F. ; Dos Santos, L. V. ; GIROTTO, G. ; MENDEZ, G. ; CHENG, R. ; HSU, Y. ; ORLANDO, M. . Exploratory Analysis of Latin American Patients in Two Randomized, Phase III Studies of Ramucirumab Alone or with Paclitaxel for Advanced Gastric Cancer. journal of cancerology , v. 2, p. 91-98, 2015.

• Dos Santos, L. V. ; LIMA, J. P. . Important Clinical Findings for Chemotherapy-Induced Nausea and Vomiting: Commentary on Molassiotis etal.. Journal of Pain and Symptom Management , v. 14, p. 827, 2014.

• CRUZ, MARCELO R. S. ; DE LIMA LOPES, GILBERTO ; SANTOS, LUCAS VIEIRA . Nanoknife and Hepatic Embolization for Colorectal Cancer Liver Metastases. Current Colorectal Cancer Reports , v. 10, p. 76-83, 2014.

• MACEDO, LÍGIA TRALDI ; LIMA, JOAO PAULO NOGUEIRA ; dos Santos, Lucas Vieira ; Sasse, Andre Deeke . Prevention strategies for chemotherapy-induced hand-foot syndrome: a systematic review and meta-analysis of prospective randomised trials. Supportive Care in Cancer , v. 22, p. 1585-1593, 2014.

• TABERNERO, J. ; TOMASEK, J. ; FILIP, D. ; PASSALACQUA, R. ; GOSWAMI, C. ; SAFRAN, H. ; Santos, L. D. ; APRILE, G. ; FERRY, D. ; CHO, J. Y. ; MELICHAR, B. ; TEHFE, M. ; TOPUZOV, E. ; ZALCBERG, J. ; CHAU, I. ; SCHWARTZ, J. ; KOSHIJI, M. ; HSU, Y. ; FUCHS, C. . O-0008 * REGARD PHASE 3, RANDOMIZED TRIAL OF RAMUCIRUMAB IN PATIENTS WITH METASTATIC GASTRIC OR GEJ ADENOCARCINOMA FOLLOWING PROGRESSION ON FIRST-LINE CHEMOTHERAPY. Annals of Oncology , v. 24, p. iv14-iv14, 2013.

• Dos Santos, L. V. ; LIMA, J. P. ; ABDALLA, K. ; CAMPOS, A. ; SANTOS, F. ; JACOME, A. ; PORTO, F. . Imatinibe-Induced Bone Edema: Case Report and Review of Literature. J NATL COMPR CANC NE , v. 11, p. 1187-1191, 2013.

• FUCHS, CHARLES S ; TOMASEK, JIRI ; YONG, CHO JAE ; DUMITRU, FILIP ; PASSALACQUA, RODOLFO ; GOSWAMI, CHANCHAL ; SAFRAN, HOWARD ; dos Santos, Lucas Vieira ; APRILE, GIUSEPPE ; FERRY, DAVID R ; MELICHAR, BOHUSLAV ; TEHFE, MUSTAPHA ; TOPUZOV, ELDAR ; ZALCBERG, JOHN RAYMOND ; CHAU, IAN ; CAMPBELL, WILLIAM ; SIVANANDAN, CHOONDAL ; PIKIEL, JOANNA ; KOSHIJI, MINORI ; HSU, YANZHI ; LIEPA, ASTRA M ; GAO, LING ; SCHWARTZ, JONATHAN D ; TABERNERO, JOSEP . Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial. Lancet (British edition) , p. 31-39, 2013.

• Lima, J. P. d. S. N. ; de Souza, F. H. ; de Andrade, D. A. P. ; Carvalheira, J. B. C. ; Dos Santos, L. V. . Independent Radiologic Review in Metastatic Colorectal Cancer: Systematic Review and Meta-Analysis. Radiology , v. 263, p. 86-95, 2012.

• dos Santos, Lucas V ; Lima, João Paulo SN ; Lima, Carmen SP ; Sasse, Emma C ; Sasse, Andre D . Is there a role for consolidative radiotherapy in the treatment of aggressive and localized Non-Hodgkin Lymphoma? A systematic review with meta-analysis. BMC Cancer (Online) , v. 12, p. 288, 2012.

• dos Santos, L. V. ; SOUZA, F. H. ; Brunetto, A. T. ; Sasse, A. D. ; Da Silveira Nogueira Lima, J. P. . Neurokinin-1 Receptor Antagonists for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review. Journal of the National Cancer Institute (Print) , v. 104, p. 1280-1292, 2012.

• V. dos Santos, Lucas ; L. Carvalho, Andre . Bcl-2 Targeted-Therapy for the Treatment of Head and Neck Squamous Cell Carcinoma. Recent Patents on Anti-Cancer Drug Discovery , v. 6, p. 45-57, 2011.

• da Silveira Nogueira Lima, João Paulo ; Nakamura, Ricardo Akiyoshi ; dos Santos, Lucas Vieira . Japanese patients equally likely to benefit from aprepitant for chemotherapy-induced nausea and vomiting prevention. Cancer Science , v. 102, p. 1112-1112, 2011.

• de Andrade, Diocésio Pinto ; Lima, João Paulo ; Lima, Alan Duarte ; Sasse, André Deeke ; dos Santos, Lucas Vieira . Bevacizumab in metastatic colorectal cancer and carcino-embryonic antigen kinetics. Anti-Cancer Drugs , v. 22, p. S15-S17, 2011.

• Dos Santos LV ; de Andrade, D. P. ; Lima, J. P. ; LIMA, J. P. S. N. . FOLFIRINOX: A Great Leap Forward, but for Whom?. Journal of Clinical Oncology , v. 29, p. 1-115, 2011.

• Dos Santos, L. V. ; Dos Anjos Jácome, A. A. ; Cárcano, F. M. ; Da Silveira Nogueira Lima, J. P. ; Serrano, S. V. . Watch and wait policy remains experimental for the management of rectal cancer. Colorectal Disease , v. 12, p. 833-833, 2010.

• Lima, João Paulo S. N. ; Santos, Lucas Vieira dos ; Sasse, Emma Chen ; Lima, Carmen Silvia Passos ; Sasse, André Deeke . Camptothecins Compared with Etoposide in Combination with Platinum Analog in Extensive Stage Small Cell Lung Cancer. Journal of Thoracic Oncology , v. 5, p. 1986-1993, 2010.

• Sasse, A. D. ; Lima, J. P. ; Sasse, E. C. ; SANTOS, L. V. . Duration of Chemotherapy for Metastatic Non-Small-Cell Lung Cancer: More May Be Not Better. Journal of Clinical Oncology , v. 27, p. e253-e253, 2009.

• Lima, João Paulo da Silveira Nogueira ; Santos, Lucas Vieira dos ; Sasse, Emma Chen ; Sasse, Andre Deeke . Optimal duration of first-line chemotherapy for advanced non-small cell lung cancer: A systematic review with meta-analysis. European Journal of Cancer , v. 45, p. 601-607, 2009.

• Alexandre Andrade dos Anjos Jácome ; dos Santos, L.V. . Câncer de Pênis. In: Faria, E. F.; Machado, R. D.. (Org.). URO-ONCOLOGIA - DUVIDAS E CONTROVERSIAS. 1ed.Ribeirão Preto: Novo Conceito, 2009, v. 1, p. 1-.

• FUCHS, C. S. ; TOMASEK, J. ; CHO, J. Y. ; TOMASELLO, G. ; GOSWAMI, C. ; dos Santos, L.V. ; Giuseppe Aprile ; FERRY, D. R. ; MELICHAR, B. ; TEHFE, M. ; TOPUZOV, E. ; ZALCBERG, JOHN RAYMOND ; Ian Chau ; Josep Tabernero ; HSU, Y. ; SCHWARTZ, J. D. ; Minori Koshiji ; Howard Safran . REGARD: A phase 3, randomized, double-blind trial of ramucirumab (RAM) and best supportive care (BSC) versus placebo (PL) and BSC in the treatment of metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma following disease progression (PD) on first-line platinum- and/or fluoropyrimidine-containing combination therapy: Age subgroup analysis.. In: 2014 ASCO Annual Meeting, 2014, Chicago, IL. J Clin Oncol, 2014. v. 32. p. suppl:abstr4057.

• dos Santos, L.V. ; FARIA, T. V. ; LIMA, A. B. C. ; ABDALLA, K. C. ; VIANA, V. A. ; TAVARES, I. R. ; MORAES, E. D. ; MELANI, A. ; CRUZ, M. R. ; Lima, J.P. . Timing of adjuvant therapy in stage II-III colorectal cancer.. In: 2014 ASCO Annual Meeting, 2014, Chiacago, IL. J Clin Oncol, 2014. v. 32. p. supp:abstr 3614.

• FUCHS, C. S. ; Jiri Tomasek ; Jae Yong Cho ; Filip Dumitru ; Rodolfo Passalacqua ; Chanchal Goswami ; Howard Safran ; Dos Santos, L. V. ; Giuseppe Aprile ; FERRY, D. R. ; Bohuslav Melichar ; Mustapha Tehfe ; Eldar Topuzov ; Josep Tabernero ; John Raymond Zalcberg ; Ian Chau ; Minori Koshiji ; Yanzhi Hsu ; SCHWARTZ, J. D. ; AJANI, J. A. . REGARD: A phase III, randomized, double-blind trial of ramucirumab and best supportive care (BSC) versus placebo and BSC in the treatment of metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing combination therapy. In: 2013 GI Cancers Symposium, 2013, San Francisco. J Clin Oncol, 2013. v. 30. p. LBA5.

• FUCHS, C. S. ; Jiri Tomasek ; Jae Yong Cho ; Dumitru Filip ; Rodolfo Passalacqua ; Chancal Goswami ; Howard Safran ; Dos Santos LV ; AL., E. . REGARD: A phase III, randomized, double-blind trial of ramucirumab and best supportive care (BSC) versus placebo and BSC in the treatment of metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing combination therapy. In: AACR Annual Meeting, 2013, Washington, DC. 2013 AACR Annual Meeting Proceedings, 2013. p. LB-67.

• dos Santos, L.V. ; João Paulo da Silveira Nogueira Lima ; Sasse, E. C. ; LIMA, C. S. P. ; Sasse, A. D. . Consolidative Radiotherapy in the Treatment of Aggressive and Localized Non-Hodgkin?s Lymphoma ? A Systematic Review with Meta-Analysis. In: 46th ASCO Annual Meeting, 2010, Chicago. 46th ASCO Annual Meeting Proceedings. Alexandria: Journal of Clinical Oncology, 2010. v. 1. p. 1.

• Sasse, A. D. ; Emma, C.S. ; Dos Santos LV ; Lima, J.P. . Oral fluoropyrimidines versus 5-fluorouracil for colorectal cancer: Results of a systematic review and meta-analysis.. In: ASCO Annual Meeting, 2009, Orlando - FL. J Clin Oncol. Alexandria - VA - USA: American Society of Clinical Oncology, 2009. v. 27. p. abstr4111.

• Emma, C.S. ; Lima, J.P. ; Dos Santos LV ; Sasse, A. D. . Irinotecan plus platinum analog (IP) compared to etoposide plus platinum analog (EP) in extensive stage small cell lung cancer (ED-SCLC): Systematic review with meta-analysis.. In: ASCO Annual Meeting, 2009, Orlando FL. J Clin Oncol. Alexandria - VA - USA: American Society of Clinical Oncology, 2009. v. 27. p. abstr8105.

• Lima, J.P. ; Nunes, J. S. ; Fuza, K. R. ; SANTOS, L. V. ; Duarte, I. L. ; SCHERR, A. J. O. ; Sasse, Andre Deeke . Impacto do Metabolismo de Tamoxifeno no Prognóstico de Pacientes em Hormonioterapia Adjuvante: Revisão Sistemática e Mata-Análise em Biologia Molecular In: XVI Congresso Brasileiro de Oncologia Clínica, 2009, Fortaleza.. In: XVI Congresso Brasileiro de Oncologia Clínica, 2009, Fortaleza. Anais do Evento - XVI Congresso Brasileiro de Oncologia Clínica. Belo Horizonte: SBOC, 2009. v. único. p. 72-72.

• Dos Santos LV ; Sasse, A. D. . Searching LILACS database is irrelevant in systematic reviews in Oncology. In: 16th Cochrane Colloquium, 2008, Freiburg. Evidenz, Fortbildung und Qualitat im Gesundheitswesen, 2008. v. 102. p. s84-S85.

• dos Santos, L. V. ; FARIA, T. V. ; LIMA, A. B. C. ; ABDALLA, K. C. ; VIANA, V. A. ; TAVARES, I. R. ; MORAES, E. D. ; MELANI, A. ; CRUZ, M. R. . Timing of adjuvant therapy in stage II-III colorectal cancer.. 2014. (Apresentação de Trabalho/Congresso).

• dos Santos, L. V. ; VIANA, L. ; LIMA, J. P. ; FELTRIN, L. ; SCAPULATEMPO, C. ; CARVALHO, A. ; Carvalheira, JBC . METFORMIN PLUS PACLITAXEL FOR METASTATIC OR RECURRENT HEAD AND NECK CANCER: FINAL RESULTS OF THE RANDOMISED PROSPECTIVE METTAX TRIAL (NCT01333852). 2014. (Apresentação de Trabalho/Congresso).

• LIMA, JP ; RODRIGUES, DN ; CANARIO, R. ; dos Santos, L.V. . COPY NUMBER OF CENTROMERE OF CHROMOSOME 17 (CEP17) AS PREDICTOR OF BENEFIT FOR ADJUVANT ANTHRACYCLINE FOR BREAST CANCER: SYSTEMATIC REVIEW WITH META-ANALYSIS. 2014. (Apresentação de Trabalho/Congresso).

• Lima, J. P. ; RODRIGUES, DN ; Cárcano, F. M. ; CRUZ, MARCELO R. S. ; dos Santos, L.V. . VEGF-A LEVEL AS A PREDICTOR OF BEVACIZUMAB BENEFIT FOR BREAST CANCER: SYSTEMATIC REVIEW WITH META-ANALYSIS. 2014. (Apresentação de Trabalho/Congresso).

• Lima, J. P. ; dos Santos, L.V. ; LIMA, C. S. P. ; Sasse, A. D. . Irinotecan-platinum (IP) compared to etoposide-platinum (EP) in extensive disease small cell lung cancer (ED-SCLC): meta-analysis with geographic origin sub-analysis. 2011. 2011. (Apresentação de Trabalho/Congresso).

• LIMA, J. P. S. N. ; Flávio Mavignier Cárcano ; SOUZA, F. H. ; dos Santos, L.V. . Blinded independent radiologic review (BIRR) versus investigator radiologic evaluation (IRE) for response assessment in metastatic colorectal cancer (mCRC): Systematic review and meta-analysis.. 2011. (Apresentação de Trabalho/Congresso).

• Cárcano, F. M. ; dos Santos, L.V. ; TARIKI, M. S. ; Serrano, S. V. ; Sasse, Andre Deeke ; LIMA, J. P. S. N. . Targeted therapy in first-line therapy of metastatic renal cell cancer (mRCC): systematic review with meta-analysis (SRMA).. 2010. (Apresentação de Trabalho/Congresso).

Outras produções

Projetos de pesquisa

• 2012 - 2014

  A Study of Herceptin (Trastuzumab) in Combination With Cisplatin/Capecitabine Chemotherapy in Patients With HER2-Positive Metastatic Gastric or Gastro-Esophageal Junction Cancer, Descrição: This randomized, open-label, multicenter, international phase IIIb study will compare the efficacy and safety of two Herceptin (trastuzumab) dosing regimens in combination with cisplatin/capecitabine chemotherapy in patients with metastatic gastric or gastro-esophageal junction adenocarcinoma. Patients who have not received prior treatment for metastatic disease will be randomized to receive Herceptin intravenously either an 8 mg/kg loading dose followed by 6 mg/kg every 3 weeks or an 8 mg/kg loading dose followed by 10 mg/kg every 3 weeks. Capecitabine will be administered for 6 cycles at a dose of 800 mg/m2 orally twice on Days 1-14 of each 3-week cycle, cisplatin will be administered intravenously for 6 cycles at a dose of 80 mg/m2 on Day 1 of each 3-week cycle. Anticipated time on study treatment is until disease progression occurs. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador.

• 2012 - Atual

  Diffuse Gastric and Esophagogastric Junction Cancer S-1 Trial (DIGEST), Descrição: The purpose of this study is to evaluate the safety and efficacy of S-1 and Cisplatin compared to 5-FU and Cisplatin in treatment of patients with metastatic diffuse gastric and esophagogastric junction cancer previously untreated with chemotherapy.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador.

• 2012 - Atual

  A Study Of The Efficacy And Safety Of Sunitinib In Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine Tumors, Descrição: The purpose of this study is to confirm the safety and efficacy of sunitinib in subjects with unresectable pancreatic neuroendocrine tumors.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador.

• 2011 - Atual

  Study of IMC-1121B (Ramucirumab) With Best Supportive Care in Patients With Gastric Cancer and Adenocarcinoma, Descrição: http://www.clinicaltrials.gov/ct2/show/NCT00917384. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador., Financiador(es): IMCLONE LLC - Auxílio financeiro.

• 2011 - Atual

  Avaliação do tempo para início do tratamento adjuvante para câncer colorretal e desfechos clínicos, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador.

• 2011 - Atual

  Avaliação de desfechos em câncer colorretal metastático, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador / Lima, J. P. - Integrante / de Andrade, D. A. P. - Integrante.

• 2010 - 2013

  LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador.

• 2009 - Atual

  Nilotinib 800 Mg And Imatinib 800 Mg For The Treatment Of Patients With Gastrointestinal Stromal Tumors (Gist) Refractory To Imatinib 400 Mg, Descrição: http://www.clinicaltrials.gov/ct2/show/NCT00751036. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador., Financiador(es): Novartis Biociencias Sa - Auxílio financeiro.

• 2009 - Atual

  Avaliação de marcadores da via EGFR-RAS-RAF em pacientes com câncer colorretal metastático, Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Lucas Vieira dos Santos - Coordenador / Jácome, A. A. A. - Integrante / Rui Manuel Reis - Integrante / Cristovam Scapulatempo Neto - Integrante / Naiara Correia Nogueira de Souza - Integrante.

Prêmios