Felipe Fregni

Full Professor de Medicina Física Reabilitação da Escola de Medicina de Harvard (Harvard Medical School) e Full Professor de Epidemiologia da Escola de Saude Publica de Harvard. Professor de Pós-Graduação do Núcleo de Neurociências (NEC) da Universidade de São Paulo (USP) e São Paulo Excellence Chair/USP (SPEC - FAPESP). Diretor do Laboratório de Neuromodulação do Hospital de Reabilitação Spaulding (Spaulding Rehabilitations Hospital). Possui doutorado em Psiquiatria pela Universidade de São Paulo (2004), mestrado pela Escola de Medicina de Harvard, mestrado pela Escola de Saúde Pública de Harvard (Harvard School of Public Health) e pós-doutorado pela Universidade de Harvard. Tem experiência na área de Medicina, com ênfase em Psiquiatria e Neurologia, atuando principalmente nos seguintes temas: estimulação transcraniana por corrente contínua, estimulação magnética transcraniana, plasticidade cerebral e metodologia em pesquisa clínica com aplicação em saúde pública.

Informações coletadas do Lattes em 03/02/2025

Acadêmico

Formação acadêmica

Doutorado em Psiquiatria

2002 - 2004

Universidade de São Paulo
Título: Comparação entre a resposta antidepressiva a terapia farmacológica e a estimulação magnética transcraniana de repetição em pacientes com doença de Parkinson
Marco A. Marcolin. Bolsista do(a): Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES, Brasil.

Mestrado em Clinical Effectiveness

2006 - 2007

Harvard School Of Public Health
Título: Re-Wiring the Brain: A New Approach using Noninvasive Brain Stimulation for the Treatment of Fibromyalgia, Ano de Obtenção: 2007
Orientador: Fran Cook
Bolsista do(a): David Rockefeller Center for Latin American Studies, DRCLAS, Brasil.

Mestrado em Scholars in Clinical Science Program

2004 - 2006

Harvard Medical School
Título: Clinical Utility of Noninvasive Brain Stimulation in Neurology, Ano de Obtenção: 2006
Orientador: Alvaro Pascual-Leone / Steven D. Freedman
Bolsista do(a): National Institute of Health, NIH, Estados Unidos.

Especialização - Residência médica

2000 - 2003

Universidade de São Paulo
Residência médica em: NeurologiaNúmero do registro: . Bolsista do(a): .

Graduação em Medicina

1994 - 1999

Universidade de São Paulo

Pós-doutorado

2004 - 2005

Pós-Doutorado. , Harvard University, HARVARD, Estados Unidos.

Idiomas

Inglês

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Espanhol

Compreende Razoavelmente, Fala Pouco, Lê Razoavelmente.

Português

Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.

Áreas de atuação

Grande área: Ciências da Saúde / Área: Medicina / Subárea: Psiquiatria.

Grande área: Ciências da Saúde / Área: Medicina / Subárea: Neurologia.

Grande área: Ciências da Saúde / Área: Saúde Coletiva.

Grande área: Ciências da Saúde / Área: Saúde Coletiva / Subárea: Epidemiologia.

Grande área: Ciências da Saúde / Área: Saúde Coletiva / Subárea: Medicina Preventiva.

Grande área: Ciências Humanas / Área: Psicologia / Subárea: Tratamento e Prevenção Psicológica/Especialidade: Treinamento e Reabilitação.

Organização de eventos

FREGNI, F. ; Boggio, PS . III Simpósio Internacional em Neuromodulação. 2011. (Congresso).

FREGNI, F. ; Boggio, PS ; Nunes J ; Baptista AF ; Lucena R ; Bonetti B . II Curso Teórico-Prático de Estimulação Cerebral Não-Invasiva. 2011. (Outro).

FREGNI, F. . I Curso de Educação Continuada em Neuromodulação. 2010. (Outro).

FREGNI, F. ; Boggio, PS . II Simpósio Internacional em Neuromodulação. 2010. (Congresso).

FREGNI, F. . Simpósio Internacional sobre Atualizações em Epilepsia. 2009. (Congresso).

FREGNI, F. ; Boggio, PS . I Simpósio Internacional em Placebo. 2009. (Congresso).

FREGNI, F. ; Boggio, PS . Modulação Cerebral em Psiquiatria. 2008. (Congresso).

Participação em eventos

Chronos 2010 I Forúm Internacional de Nutrição Funcional, Prevenção de Doenças Degenerativas e Envelhecimento com Qualidade de Vida."Atividade cerebral e salutogenesis - Modulando a atividade cerebral para produzir saúde". 2010. (Outra).

Chronos 2010 - I Forúm Internacional de Nutrição Funcional de Doenças e Envelhecimento com qualidade de Vida"."Estimulação magnética transcraniana(TMS) - Modulação cosnitiva com técnicas de neuromodulação". 2010. (Outra).

Orientou

Rafaela Gimenes

Uso da Estimulação Transcraniana por Corrente Contínua no controle da dor em pacientes com fibromialgia; Início: 2005; Tese (Doutorado em Medicina (Neurologia)) - Universidade de São Paulo; (Coorientador);

Karen Dionisio

Uso da Estimulação Magnética Transcraniana para reduzir a espasticidade em pacientes com espasticidade cerebral; Início: 2005; Tese (Doutorado em Medicina (Neurologia)) - Universidade de São Paulo; (Coorientador);

Maria Passos

Início: 2007; Beth Israel Deaconess Medical Center / Harvard Medical School;

Asli Demirtas-Tatlides

Início: 2006; Beth Israel Deaconess Medical Center / Harvard Medical School, National Institute of Health;

Julie Williams

Reabilitação motora em pacientes com AVC com uso de terapia combinada de restrição de movimentos e Estimulação Trancraniana por Corrente Contínua; Início: 2007; Iniciação científica (Graduando em Medicina) - Harvard University, American Heart Association; (Orientador);

Soroush Zaghi

Study of tDCS for patients with migraine; Início: 2007 - Beth Israel Deaconess Medical Center / Harvard Medical School, Pasteur program; (Orientador);

Andre Brunoni

BDNF como um marcador para os efeitos da Estimulação Magnética; Início: 2008; Orientação de outra natureza; Harvard University; (Orientador);

Mariana Z

Lopes; Associação de atividade cerebral e desconforto respiratório; Início: 2007; Orientação de outra natureza; Harvard University; (Orientador);

Leah Schweid

Study of neglect in cats using tDCS; 2007; Dissertação (Mestrado em Neuroscience) - Boston University, National Institute of Health; Coorientador: Felipe Fregni;

Fabiana Tenório Gomes da Silva

Efeitos neurofisiológicos e clínicos associados à estimulação do nervo mediano combinada com exercício físico sobre a dor experimental em indivíduos sedentários: estudo randomizado e duplo cego; 2020; Tese (Doutorado em Neurociências e Comportamento) - Universidade de São Paulo, ; Orientador: Felipe Fregni;

Camila Bonin Pinto

Efeito da terapia combinada da EMTr com fluoxetina na reabilitação da função motora de pacientes pós AVE isquêmico; 2018; Tese (Doutorado em Neurociências e comportamento) - Universidade de São Paulo, ; Orientador: Felipe Fregni;

Mariana Emerenciano de Mendonça

Terapia combinada com uso da estimulação trancraniana com corrente contínua associado ao treino de exercício aeróbico em pacientes com fibromialgia: ensaio clínico, randomizado, duplo-cego; 2017; Tese (Doutorado em Neurociências e comportamento) - Universidade de São Paulo, ; Orientador: Felipe Fregni;

Andre Brunoni

Tratamento do transtorno depressivo maior com estimulação transcraniana por corrente continua: ensaio clínico, aleatorizado, duplo cedo, fatorial; 2012; Tese (Doutorado em Medicina (Neurologia)) - Universidade de São Paulo, ; Orientador: Felipe Fregni;

Merari Jizar

Uso da Estimulação Transcraniana por Corrente Contínua na modulação do desbalanço da excitabilidade cortical bi-hemisférica em pacientes com AVC; 2006; Iniciação Científica; (Graduando em Psicologia) - Universidade Presbiteriana Mackenzie; Orientador: Felipe Fregni;

Moises C Lima

Uso da estimulação cerebral em dor crônica; 2005; Iniciação Científica - Universidade de São Paulo; Orientador: Felipe Fregni;

Sami Bjawa

Transcallosal inhibition in major depression; 2005; Iniciação Científica - Harvard Medical School; Orientador: Felipe Fregni;

Marcelo C

Santos; Alterações na função e excitabilidade motora após o uso da Estimulação Transcraniana por Corrente Contínua em pacientes com doença de Parkinson; 2005; Iniciação Científica; (Graduando em Medicina) - Universidade de São Paulo; Orientador: Felipe Fregni;

Alice Nunes

Uso de sessões repetidas de Estimulação Transcraniana por Corrente Contínua na recuperação motora de pacientes com AVC; 2005; Iniciação Científica; (Graduando em Medicina) - Universidade de São Paulo; Orientador: Felipe Fregni;

Adriana Lopes

Efeitos motores da Estimulação Transcraniana por Corrente Contínua em pacientes com doença de Parkinson; 2005; Iniciação Científica; (Graduando em Psicologia) - Universidade Presbiteriana Mackenzie; Orientador: Felipe Fregni;

Renata Marcondes

Uso da Estimulação Magnética Transcraniana em pacientes com zumbido; 2005; Orientação de outra natureza; (Medicina) - Harvard University; Orientador: Felipe Fregni;

Raphael Boechat

Estimulação Magnética Transcraniana na prática clínica e distúrbios psiquiátricos; 2005; Orientação de outra natureza; (Medicina) - Harvard University; Orientador: Felipe Fregni;

Roberta Ferrucci

Efeitos da Estimulação Transcraniana por Corrente Contínua na memória operacional em pacientes com doença de Parkinson; 2005; Orientação de outra natureza; (Medicina) - Harvard University; Orientador: Felipe Fregni;

Franca Parizi

Visceral pain; 2005; Orientação de outra natureza - Beth Israel Deaconess Medical Center / Harvard Medical School; Orientador: Felipe Fregni;

Paulo Sérgio Boggio

Alterações na memória operacional de trabalho com o uso de Estimulação Transcraniana por Corrente Contínua; 2004; Orientação de outra natureza; (Psciologia) - Universidade de São Paulo; Orientador: Felipe Fregni;

Produções bibliográficas

GIANLORENCO, ANNA CAROLYNA ; PACHECO-BARRIOS, KEVIN ; CAMARGO, LUCAS ; PICHARDO, ELLY ; CHOI, HYUK ; SONG, JAE-JUN ; Fregni, Felipe . Understanding the Effects of Non-Invasive Transauricular Vagus Nerve Stimulation On EEG and HRV. Jove-Journal of Visualized Experiments , v. 19, p. 203, 2024.
GIANLORENÇO, ANNA CAROLYNA ; COSTA, VALTON ; FABRIS-MORAES, WALTER ; MENACHO, MARYELA ; ALVES, LUANA GOLA ; MARTINEZ-MAGALLANES, DANIELA ; Fregni, Felipe . Cluster analysis in fibromyalgia: a systematic review. RHEUMATOLOGY INTERNATIONAL (BERLIN. INTERNET) , v. 15, p. 1, 2024.
NEVES, MARIANA VITA MILAZZOTTO ; FURLAN, LEONARDO ; Fregni, Felipe ; Battistella, Linamara Rizzo ; SIMIS, MARCEL . Robotic-Assisted Gait Training (RAGT) in Stroke Rehabilitation: A Pilot Study. Archives of Rehabilitation Research and Clinical Translation , v. 5, p. 100255, 2023.
PIMENTA, DANIELLE CAROLINA ; LIMA, DANIEL ; SLAWKA, ERIC ; PACHECO-BARRIOS, KEVIN ; Fregni, Felipe . Editorial: Bench to Bedside - the translation of intracortical inhibition marker to clinical practice. PRINCIPLES AND PRATICE OF CLINICAL RESEARCH , v. 8, p. 92-97, 2023.
CHOU, LI-WEI ; HOU, SHIANG-LIN ; LEE, HUI-MIN ; Fregni, Felipe ; YEN, ALICE ; CHEN, VINCENT ; WEI, SHUN-HWA ; KAO, CHUNG-LAN . Effects of Noise Electrical Stimulation on Proprioception, Force Control, and Corticomuscular Functional Connectivity. IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING , v. 31, p. 2518-2524, 2023.
PACHECO-BARRIOS, KEVIN ; PIMENTA, DANIELLE CAROLINA ; PESSOTTO, ANNE VICTORIO ; Fregni, Felipe . Motor Cortex Inhibition and Facilitation Correlates with Fibromyalgia Compensatory Mechanisms and Pain: A Cross-Sectional Study. Biomedicines , v. 11, p. 1543, 2023.
TOCCHETTO, BETINA FRANCESCHINI ; RAMALHO, LETICIA ; ZORTEA, MAXCIEL ; BRUCK, SAMARA MACHADO ; TOMEDI, RAFAELA BRUGNERA ; ALVES, RAEL LOPES ; Torres, Iraci Lucena da Silva ; Fregni, Felipe ; Caumo, Wolnei . Peripheral body temperature rhythm as a marker of the severity of depression symptoms in fibromyalgia. BIOLOGICAL PSYCHOLOGY , v. 177, p. 108494, 2023.
PACHECO-BARRIOS, KEVIN ; VELASQUEZ-RIMACHI, VICTOR ; NAVARRO-FLORES, ALBA ; HUERTA-ROSARIO, ANDRELY ; MORÁN-MARIÑOS, CRISTIAN ; MOLINA, ROBERTO A ; FARROÑAY-GARCÍA, CHANDEL ; METCALF, TATIANA ; Fregni, Felipe ; ALVA-DÍAZ, CARLOS . Primary headache disorders in Latin America and the Caribbean: A meta-analysis of population-based studies. CEPHALALGIA , v. 43, p. 033310242211282, 2023.
UYGUR-KUCUKSEYMEN, ELIF ; PACHECO-BARRIOS, KEVIN ; YUKSEL, BURCU ; GONZALEZ-MEGO, PAOLA ; SOYSAL, AYSUN ; Fregni, Felipe . Non-invasive brain stimulation on clinical symptoms in multiple sclerosis patients: A systematic review and meta-analysis. Multiple Sclerosis and Related Disorders , v. 78, p. 104927, 2023.
DE MELO, PAULO S. ; PARENTE, JOÃO ; REBELLO-SANCHEZ, INGRID ; MARDUY, ANNA ; GIANLORENCO, ANNA CAROLYNA ; KYUNG KIM, CHI ; CHOI, HYUK ; SONG, JAE-JUN ; Fregni, Felipe . Understanding the Neuroplastic Effects of Auricular Vagus Nerve Stimulation in Animal Models of Stroke: A Systematic Review and Meta-Analysis. NEUROREHABILITATION AND NEURAL REPAIR , v. 37, p. 564-576, 2023.
TEIXEIRA, PAULO E.P. ; PACHECO-BARRIOS, KEVIN ; BRANCO, LUIS CASTELO ; DE MELO, PAULO S. ; MARDUY, ANNA ; Caumo, Wolnei ; PAPATHEODOROU, STEFANIA ; KEYSOR, JULIE ; Fregni, Felipe . The Analgesic Effect of Transcranial Direct Current Stimulation in Fibromyalgia: A Systematic Review, Meta-Analysis, and Meta-Regression of Potential Influencers of Clinical Effect. NEUROMODULATION , v. 26, p. 715-727, 2023.
LEONARDO, SOFIA ; Fregni, Felipe . Association of inflammation and cognition in the elderly: A systematic review and meta-analysis. Frontiers in Aging Neuroscience , v. 15, p. 1, 2023.
GONÇALVES, FERNANDA DE TOLEDO ; MARQUES, LUCAS MURRINS ; PESSOTTO, ANNE VICTÓRIO ; BARBOSA, SARA PINTO ; Imamura, Marta ; SIMIS, MARCEL ; Fregni, Felipe ; Battistella, Linamara . OPRM1 and BDNF polymorphisms associated with a compensatory neurophysiologic signature in knee osteoarthritis patients. NEUROPHYSIOLOGIE CLINIQUE-CLINICAL NEUROPHYSIOLOGY , v. 53, p. 102917, 2023.
PARENTE, JOAO ; GIANLORENCO, ANNA CAROLYNA ; REBELLO-SANCHEZ, INGRID ; KIM, MINKYUNG ; PRATI, JOSE MARIO ; KIM, CHI KYUNG ; CHOI, HYUK ; SONG, JAE-JUN ; Fregni, Felipe . Neural, Anti-inflammatory, and Clinical Effects of Transauricular Vagus Nerve Stimulation in Major Depressive Disorder: A Systematic Review. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY , v. 1, p. 1, 2023.
LIMA, DANIEL ; PACHECO-BARRIOS, KEVIN ; SLAWKA, ERIC ; CAMARGO, LUCAS ; CASTELO-BRANCO, LUIS ; CARDENAS-ROJAS, ALEJANDRA ; NETO, MOACIR SILVA ; Fregni, Felipe . The role of symptoms severity, heart rate, and central sensitization for predicting sleep quality in patients with fibromyalgia. PAIN MEDICINE , v. 1, p. 1, 2023.
THIBAUT, AURORE ; Fregni, Felipe ; ESTRANEO, ANNA ; FIORENZA, SALVATORE ; NOE, ENRIQUE ; LLORENS, ROBERTO ; FERRI, JOAN ; FORMISANO, RITA ; MORONE, GIOVANNI ; BENDER, ANDREAS ; ROSENFELDER, MARTIN ; LAMBERTI, GIANFRANCO ; KODRATYEVA, EKATERINA ; KONDRATYEV, SERGEY ; LEGOSTAEVA, LIUDMILA ; SUPONEVA, NATALIA ; KREWER, CARMEN ; MÜLLER, FRIEDEMANN ; DARDENNE, NADIA ; JEDIDI, HAROUN . Sham-controlled randomized multicentre trial of transcranial direct current stimulation for prolonged disorders of consciousness. EUROPEAN JOURNAL OF NEUROLOGY , v. 30, p. 3016-3031, 2023.
MENACHO, MARYELA DE OLIVEIRA ; PACHECO'BARRIOS, KEVIN ; MENDES, AUGUSTO J. ; SATO, TATIANA DE OLIVEIRA ; Fregni, Felipe ; GIANLORENÇO, ANNA CAROLYNA LEPESTEUR . Exercise effects on motor function, manual dexterity, and brain oscillatory activity in individuals with Parkinson's disease: Randomized controlled trial protocol. PHYSIOTHERAPY RESEARCH INTERNATIONAL , v. 1, p. 1, 2023.
SIMIS, MARCEL ; THIBAUT, AURORE ; Imamura, Marta ; Battistella, Linamara Rizzo ; Fregni, Felipe . Neurophysiological biomarkers of motor improvement from Constraint-Induced Movement Therapy and Robot-Assisted Therapy in participants with stroke. Frontiers in Human Neuroscience , v. 17, p. 1, 2023.
ZANCANARO, MAYRA ; STEIN, DIRSON J. ; LOPES, BETTEGA C. ; DE SOUZA, ANDRESSA ; STRÖHER TOLEDO, ROBERTA ; DE SOUZA, ALESSANDRA H. ; OLIVEIRA, SARA M. ; VISIOLI, FERNANDA ; SANCHES, PAULO R.S. ; Fregni, Felipe ; Caumo, Wolnei ; TORRES, IRACI L.S. . Preemptive transcranial direct current stimulation induces analgesia, prevents chronic inflammation and fibrosis, and promotes tissue repair in a rat model of postoperative pain. NEUROSCIENCE LETTERS , v. 813, p. 137407, 2023.
Imamura, Marta ; REBELLO'SANCHEZ, INGRID ; PARENTE, JOAO ; MARDUY, ANNA ; VASQUEZ'AVILA, KAREN ; PACHECO'BARRIOS, KEVIN ; CASTELO'BRANCO, LUIS ; SIMIS, MARCEL ; Battistella, Linamara ; Fregni, Felipe . Factors associated with pain pressure threshold in both local and remote sites in knee osteoarthritis. PM&R , v. 1, p. 1, 2023.
PARRON FERNANDES, BIANCA BARROS ; DODURGALI, MUSTAFA REHA ; ROSSETTI, CARLOS AUGUSTO ; PACHECO-BARRIOS, KEVIN ; Fregni, Felipe . Editorial - The Secret Life of Retractions in Scientific Publications. PRINCIPLES AND PRATICE OF CLINICAL RESEARCH , v. 9, p. 1, 2023.
ALMARIE, BASSEL ; TEIXEIRA, PAULO E. P. ; PACHECO-BARRIOS, KEVIN ; ROSSETTI, CARLOS AUGUSTO ; Fregni, Felipe . Editorial - The Use of Large Language Models in Science: Opportunities and Challenges. PRINCIPLES AND PRATICE OF CLINICAL RESEARCH , v. 9, p. 1/2023, 2023.
PINTO, CAMILA B ; PACHECO-BARRIOS, KEVIN ; SALEH VELEZ, FADDI G ; GUNDUZ, MUHAMMED E ; MÜNGER, MARIONNA ; Fregni, Felipe . Detangling the Structural Neural Correlates Associated with Resting versus Dynamic Phantom Limb Pain Intensity Using a Voxel-based Morphometry Analysis. PAIN MEDICINE , v. 24, p. 528-537, 2023.
EDWARDS, DYLAN J. ; LIU, CHARLES Y. ; DUNNING, KARI ; Fregni, Felipe ; LAINE, JARMO ; LEIBY, BENJAMIN E. ; ROGERS, LYNN M. ; HARVEY, RICHARD L. . Electric Field Navigated 1-Hz rTMS for Poststroke Motor Recovery: The E-FIT Randomized Controlled Trial. STROKE , v. 54, p. 2254-2264, 2023.
KIM, ANGELA YUN ; MARDUY, ANNA ; DE MELO, PAULO S. ; GIANLORENCO, ANNA CAROLYNA ; KIM, CHI KYUNG ; CHOI, HYUK ; SONG, JAE-JUN ; Fregni, Felipe . Safety of transcutaneous auricular vagus nerve stimulation (taVNS): a systematic review and meta-analysis. Scientific Reports , v. 12, p. 1, 2022.
PACHECO-BARRIOS, KEVIN ; CARVALHO, SANDRA ; LEITE, JORGE ; Caumo, Wolnei ; Fregni, Felipe . Editorial: Optimization strategies for pain management with neuromodulation. Frontiers in Pain Research , v. 3, p. 1, 2022.
UEHARA, LAURA ; CORRÊA, JOÃO CARLOS FERRARI ; RITTI, RAPHAEL ; LEITE, PAULO ; DE FARIA, DEIVIDE RAFAEL GOMES ; PACHECO-BARRIOS, KEVIN ; CASTELO-BRANCO, LUIS ; Fregni, Felipe ; CORRÊA, FERNANDA ISHIDA . Transcutaneous auricular vagus nerve stimulation effects on inflammatory markers and clinical evolution of patients with COVID-19: a pilot randomized clinical trial. Expert Review of Medical Devices , v. 19, p. 915-920, 2022.
GIANLORENCO, ANNA CAROLYNA L. ; DE MELO, PAULO S. ; MARDUY, ANNA ; KIM, ANGELA YUN ; KIM, CHI KYUNG ; CHOI, HYUK ; SONG, JAE-JUN ; Fregni, Felipe . Electroencephalographic Patterns in taVNS: A Systematic Review. Biomedicines , v. 10, p. 2208, 2022.
MENDES, AUGUSTO J. ; PACHECO-BARRIOS, KEVIN ; LEMA, ALBERTO ; GONÇALVES, ÓSCAR F. ; Fregni, Felipe ; LEITE, JORGE ; CARVALHO, SANDRA . Modulation of the cognitive event-related potential P3 by transcranial direct current stimulation: Systematic review and meta-analysis. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS , v. 132, p. 894-907, 2022.
CASTELO-BRANCO, LUIS ; CARDENAS-ROJAS, ALEJANDRA ; PACHECO-BARRIOS, KEVIN ; TEIXEIRA, PAULO E.P. ; GONZALEZ-MEGO, PAOLA ; VASQUEZ-AVILA, KAREN ; COSTA CORTEZ, PABLO ; MARDUY, ANNA ; REBELLO-SANCHEZ, INGRID ; PARENTE, JOAO ; MARZOUK, S. ; Fregni, Felipe . Can neural markers be used for fibromyalgia clinical management?. PRINCIPLES AND PRATICE OF CLINICAL RESEARCH , v. 8, p. 28-33, 2022.
HO, JOHNSON ; SLAWKA, ERIC ; PACHECO-BARRIOS, KEVIN ; CARDENAS-ROJAS, ALEJANDRA ; CASTELO-BRANCO, LUIS ; Fregni, Felipe . The pros and cons of tDCS as a therapeutic tool in the rehabilitation of chronic pain. PRINCIPLES AND PRATICE OF CLINICAL RESEARCH , v. 8, p. 26-30, 2022.
CASTELO-BRANCO, LUIS ; CARDENAS-ROJAS, ALEJANDRA ; REBELLO-SANCHEZ, INGRID ; PACHECO-BARRIOS, KEVIN ; DE MELO, PAULO S. ; GONZALEZ-MEGO, PAOLA ; MARDUY, ANNA ; VASQUEZ-AVILA, KAREN ; COSTA CORTEZ, PABLO ; PARENTE, JOAO ; TEIXEIRA, PAULO E. P. ; ROSA, GLEYSSON ; MCINNIS, KELLY ; Caumo, Wolnei ; Fregni, Felipe . Temporal Summation in Fibromyalgia Patients: Comparing Phasic and Tonic Paradigms. Frontiers in Pain Research , v. 3, p. 1, 2022.
REBELLO-SANCHEZ, INGRID ; MARDUY, ANNA ; PIMENTA, DANIELLE CAROLINA ; PACHECO-BARRIOS, KEVIN ; CARDENAS-ROJAS, ALEJANDRA ; Datta, Abhishek ; LIMA, DANIEL ; ROSA, GLEYSSON RODRIGUES ; Fregni, Felipe ; NAZIM, KAMRAN ; PARENTE, JOAO ; SLAWKA, ERIC . Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition. Jove-Journal of Visualized Experiments , v. 1, p. 1, 2022.
SILVA-FILHO, EDSON ; PILLONI, GIUSEPPINA ; CHARVET, LEIGH E. ; Fregni, Felipe ; BRUNONI, ANDRÉ R. ; Bikson, Marom . Factors supporting availability of home-based Neuromodulation using remote supervision in middle-income countries; Brazil experience. Brain Stimulation , v. 15, p. 385-387, 2022.
CORRÊA, FERNANDA ISHIDA ; CARNEIRO COSTA, GLAUCIO ; LEITE SOUZA, PAULO ; MARDUY, ANNA ; PARENTE, JOAO ; FERREIRA DA CRUZ, STEFANY ; DE SOUZA CUNHA, MICAELLY ; BEBER FREITAS, MAIK ; CORREA ALVES, DAVID ; SILVA, SORAIA MICAELA ; FERRARI CORRÊA, JOÃO CARLOS ; Fregni, Felipe . Additive effect of transcranial direct current stimulation (tDCS) in combination with multicomponent training on elderly physical function capacity: a randomized, triple blind, controlled trial. PHYSIOTHERAPY THEORY AND PRACTICE , v. 1, p. 1-14, 2022.
Fregni, Felipe ; EL-HAGRASSY, MIRRET M ; PACHECO-BARRIOS, KEVIN ; CARVALHO, SANDRA ; LEITE, JORGE ; SIMIS, MARCEL ; BRUNELIN, JEROME ; Nakamura-Palacios, Ester Miyuki ; MARANGOLO, PAOLA ; VENKATASUBRAMANIAN, GANESAN ; SAN-JUAN, DANIEL ; Caumo, Wolnei ; Bikson, Marom ; BRUNONI, ANDRÉ R ; CARDENAS-ROJAS, ALEJANDRA ; GIANNONI-LUZA, STEFANO ; LEAO, JUDAH ; TEIXEIRA LEFFA, DOUGLAS ; MEJIA-PANDO, PIERO F ; ALEJANDRA LUNA-CUADROS, MARIA . Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY , v. 24, p. 256-313, 2021.
ANDRESSA DE SOUZA, JANAINA ; FERRARI CORRÊA, JOÃO CARLOS ; MARDUY, ANNA ; DALL'AGNOL, LETIZZIA ; GOMES DE SOUSA, MARIA HELENA ; NUNES DA SILVA, VICTOR ; ALVES, ANDRÉ BARRETO ; SILVA, SORAIA MICAELA ; Fregni, Felipe ; CORRÊA, FERNANDA ISHIDA . To Combine or Not to Combine Physical Therapy With tDCS for Stroke With Shoulder Pain? Analysis From a Combination Randomized Clinical Trial for Rehabilitation of Painful Shoulder in Stroke. Frontiers in Pain Research , v. 2, p. 1, 2021.
CARDENAS-ROJAS, ALEJANDRA ; PACHECO-BARRIOS, KEVIN ; CASTELO-BRANCO, LUIS ; GIANNONI-LUZA, STEFANO ; BALBUENA-PAREJA, ANA ; LUNA-CUADROS, MARIA ALEJANDRA ; VASCONCELOS FELIPPE, LUNA ; UYGUR-KUCUKSEYMEN, ELIF ; GONZALEZ-MEGO, PAOLA ; GUNDUZ, MUHAMMED ENES ; SHAIKH, EMAD SALMAN ; GIANLORENCO, ANNA CAROLYNA LEPESTEUR ; Fregni, Felipe . Barriers and facilitators for clinical trial participation of underrepresented and non-underrepresented fibromyalgia patients: A cross-sectional internet survey. HELIYON , v. 7, p. e07475, 2021.
DONADEL, DANIELA GABIATTI ; ZORTEA, MAXCIEL ; Torres, Iraci L. S. ; Fregni, Felipe ; Caumo, Wolnei . The mapping of cortical activation by near-infrared spectroscopy might be a biomarker related to the severity of fibromyalgia symptoms. Scientific Reports , v. 11, p. 1, 2021.
PINTO, ANA CAROLINA PEREIRA NUNES ; PIVA, SARA REGINA ; VIEIRA, ALÉXIA GABRIELA DA SILVA ; GOMES, SAMANTHA GUERRA CABÓ NUNES ; ROCHA, ALINE PEREIRA ; TAVARES, DANIELA REGINA BRANDÃO ; SANTANA, MÁRCIA VALÉRIA DE ANDRADE ; CARLESSO, CRISTIANE ; ANDRIOLO, ADAGMAR ; SANTOS, FANIA CRISTINA ; Fregni, Felipe ; TREVISANI, VIRGÍNIA FERNANDES MOÇA . Transcranial direct current stimulation for fatigue in patients with Sjogren?s syndrome: A randomized, double-blind pilot study. Brain Stimulation , v. 14, p. 141-151, 2021.
PACHECO-BARRIOS, KEVIN ; CARDENAS-ROJAS, ALEJANDRA ; DE MELO, PAULO S. ; MARDUY, ANNA ; GONZALEZ-MEGO, PAOLA ; CASTELO-BRANCO, LUIS ; MENDES, AUGUSTO J. ; VÁSQUEZ-ÁVILA, KAREN ; TEIXEIRA, PAULO E. P. ; GIANLORENCO, ANNA CAROLYNA LEPESTEUR ; Fregni, Felipe . Home-based transcranial direct current stimulation (tDCS) and motor imagery for phantom limb pain using statistical learning to predict treatment response: an open-label study protocol. PRINCIPLES AND PRATICE OF CLINICAL RESEARCH , v. 7, p. 8-22, 2021.
PACHECO-BARRIOS, KEVIN ; DE MELO, PAULO SAMPAIO ; VASQUEZ-AVILA, KAREN ; CARDENAS-ROJAS, ALEJANDRA ; GONZALEZ-MEGO, PAOLA ; MARDUY, ANNA ; PARENTE, JOAO ; REBELLO-SANCHEZ, INGRID ; CORTEZ, PABLO ; WHALEN, MEGHAN ; CASTELO-BRANCO, LUIS ; Fregni, Felipe . Accelerating the translation of research findings to clinical practice: insights from phantom limb pain clinical trials. PRINCIPLES AND PRATICE OF CLINICAL RESEARCH , v. 7, p. 1-7, 2021.
LEMA, ALBERTO ; CARVALHO, SANDRA ; Fregni, Felipe ; GONÇALVES, ÓSCAR F. ; LEITE, JORGE . The effects of direct current stimulation and random noise stimulation on attention networks. Scientific Reports , v. 11, p. 6201, 2021.
SIMIS, MARCEL ; DORUK CAMSARI, DENIZ ; Imamura, Marta ; FILIPPO, THAIS RAQUEL MARTINS ; RUBIO DE SOUZA, DANIEL ; Battistella, Linamara Rizzo ; Fregni, Felipe . Electroencephalography as a Biomarker for Functional Recovery in Spinal Cord Injury Patients. Frontiers in Human Neuroscience , v. 15, p. 1, 2021.
THIBAUT, AURORE ; SHIE, VIVIAN L. ; RYAN, COLLEEN M. ; Zafonte, Ross ; OHRTMAN, EMILY A. ; SCHNEIDER, JEFFREY C. ; Fregni, Felipe . A review of burn symptoms and potential novel neural targets for non-invasive brain stimulation for treatment of burn sequelae. BURNS , v. 47, p. 525-537, 2021.
TOLEDO, ROBERTA STRÖHER ; STEIN, DIRSON JOÃO ; SANCHES, PAULO ROBERTO STEFANI ; DA SILVA, LISIANE SANTOS ; MEDEIROS, HELOUISE RICHARDT ; Fregni, Felipe ; Caumo, Wolnei ; TORRES, IRACI L.S. . rTMS induces analgesia and modulates neuroinflammation and neuroplasticity in neuropathic pain model rats. BRAIN RESEARCH , v. 1762, p. 147427, 2021.
TAVARES, DANIELA REGINA BRANDÃO ; OKAZAKI, JANE ERIKA FRAZAO ; SANTANA, MARCIA VALÉRIA DE ANDRADE ; PINTO, ANA CAROLINA PEREIRA NUNES ; TUTIYA, KARINA KURAOKA ; GAZONI, FERNANDA MARTINS ; PINTO, CAMILA BONIN ; SANTOS, FANIA CRISTINA ; Fregni, Felipe ; TREVISANI, VIRGINIA FERNANDES MOÇA . Motor cortex transcranial direct current stimulation effects on knee osteoarthritis pain in elderly subjects with dysfunctional descending pain inhibitory system: A randomized controlled trial. Brain Stimulation , v. 14, p. 477-487, 2021.
SOLDATELLI, MATHEUS DORIGATTI ; SIEPMANN, TIMO ; ILLIGENS, BEN MIN-WOO ; SOUZA DOS SANTOS, VINICIUS ; LUCENA DA S TORRES, IRACI ; Fregni, Felipe ; Caumo, Wolnei . Mapping of predictors of the disengagement of the descending inhibitory pain modulation system in fibromyalgia: an exploratory study. British Journal Of Pain , v. 15, p. 221-233, 2021.
SIMIS, MARCEL ; Imamura, Marta ; SAMPAIO DE MELO, PAULO ; MARDUY, ANNA ; Battistella, Linamara ; Fregni, Felipe . Deficit of Inhibition as a Marker of Neuroplasticity (DEFINE Study) in Rehabilitation: A Longitudinal Cohort Study Protocol. Frontiers in Neurology , v. 12, p. 1, 2021.
IUAMOTO, LEANDRO RYUCHI ; Imamura, Marta ; SAMESHIMA, KOICHI ; MEYER, ALBERTO ; SIMIS, MARCEL ; Battistella, Linamara Rizzo ; Fregni, Felipe . Functional Changes in Cortical Activity of Patients Submitted to Knee Osteoarthritis Treatment. AMERICAN JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION , v. 101, p. 920-930, 2021.
BANDEIRA, JANETE SHATKOSKI ; ANTUNES, LUCIANA DA CONCEIÇÃO ; SOLDATELLI, MATHEUS DORIGATTI ; SATO, JOÃO RICARDO ; Fregni, Felipe ; Caumo, Wolnei . Functional Spectroscopy Mapping of Pain Processing Cortical Areas During Non-painful Peripheral Electrical Stimulation of the Accessory Spinal Nerve. Frontiers in Human Neuroscience , v. 13, p. 1, 2019.
CARVALHO, FABIANA ; BRIETZKE, ALINE PATRÍCIA ; GASPARIN, ASSUNTA ; DOS SANTOS, FRANCIELE PEREIRA ; VERCELINO, RAFAEL ; BALLESTER, RAFAEL FIRMINO ; SANCHES, PAULO ROBERTO STEFANI ; DA SILVA, DANTON PEREIRA ; Torres, Iraci L. S. ; Fregni, Felipe ; Caumo, Wolnei . Home-Based Transcranial Direct Current Stimulation Device Development: An Updated Protocol Used at Home in Healthy Subjects and Fibromyalgia Patients. Jove-Journal of Visualized Experiments , v. 1, p. 57614, 2018.
ANTAL, A. ; ALEKSEICHUK, I. ; BIKSON, M. ; BROCKMÖLLER, J. ; BRUNONI, A.R. ; CHEN, R. ; COHEN, L.G. ; DOWTHWAITE, G. ; ELLRICH, J. ; FLÖEL, A. ; FREGNI, F. ; GEORGE, M.S. ; HAMILTON, R. ; HAUEISEN, J. ; HERRMANN, C.S. ; HUMMEL, F.C. ; LEFAUCHEUR, J.P. ; LIEBETANZ, D. ; LOO, C.K. ; MCCAIG, C.D. . Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines. CLINICAL NEUROPHYSIOLOGY , v. 128, p. 1774-1809, 2017.
Mendonca, Mariana E. ; SIMIS, MARCEL ; GRECCO, LUANDA C. ; BATTISTELLA, LINAMARA R. ; BAPTISTA, ABRAHÃO F. ; Fregni, Felipe . Transcranial Direct Current Stimulation Combined with Aerobic Exercise to Optimize Analgesic Responses in Fibromyalgia: A Randomized Placebo-Controlled Clinical Trial. Frontiers in Human Neuroscience , v. 10, p. 1-12, 2016.
MORALES-QUEZADA, LEON ; COSMO, CAMILA ; CARVALHO, SANDRA ; LEITE, JORGE ; CASTILLO-SAAVEDRA, LAURA ; ROZISKY, JOANNA R. ; Fregni, Felipe . Cognitive effects and autonomic responses to transcranial pulsed current stimulation. Experimental Brain Research , v. 233, p. 701-709, 2015.
CHASSOT, MÔNICA ; DUSSAN-SARRIA, JAIRO ALBERTO ; SEHN, FRANCISLEA CRISTINA ; DEITOS, ALÍCIA ; DE SOUZA, ANDRESSA ; VERCELINO, RAFAEL ; TORRES, IRACI LS ; Fregni, Felipe ; Caumo, Wolnei . Electroacupuncture analgesia is associated with increased serum brain-derived neurotrophic factor in chronic tension-type headache: a randomized, sham controlled, crossover trial. BMC Complementary and Alternative Medicine (Online) , v. 15, p. 144, 2015.
DA SILVA, NÁDIA REGINA JARDIM ; LASTE, GABRIELA ; DEITOS, ALÍCIA ; STEFANI, LUCIANA CADORE ; CAMBRAIA-CANTO, GUSTAVO ; TORRES, IRACI L. S. ; BRUNONI, A. R. ; FREGNI, F. ; CAUMO, WOLNEI . Combined neuromodulatory interventions in acute experimental pain: assessment of melatonin and non-invasive brain stimulation. Frontiers in Behavioral Neuroscience , v. 9, p. x, 2015.
RÊGO, GABRIEL G. ; LAPENTA, OLÍVIA M. ; MARQUES, LUCAS M. ; COSTA, THIAGO L. ; LEITE, JORGE ; CARVALHO, SANDRA ; GONÇALVES, ÓSCAR F. ; BRUNONI, A. R. ; FREGNI, F. ; Boggio, Paulo S. . Hemispheric dorsolateral prefrontal cortex lateralization in the regulation of empathy for pain. Neuroscience Letters (Print) , v. 594, p. 12-16, 2015.
KNIJNIK, LEONARDO M. ; DUSSÁN-SARRIA, JAIRO A. ; ROZISKY, JOANNA R. ; TORRES, IRACI L. S. ; BRUNONI, A. R. ; FREGNI, F. ; CAUMO, WOLNEI . Repetitive Transcranial Magnetic Stimulation for Fibromyalgia: Systematic Review and Meta-Analysis. Pain Practice (Print) , v. x, p. n/a-n/a, 2015.
FREGNI, F. ; NITSCHE, M. A. ; LOO, C. K. ; BRUNONI, A. R. ; MARANGOLO, P. ; LEITE, J. ; CARVALHO, S. ; BOLOGNINI, N. ; CAUMO, W. ; PAIK, N. J. ; SIMIS, M. ; UEDA, K. ; EKHTIARI, H. ; LUU, P. ; TUCKER, D. M. ; TYLER, W. J. ; BRUNELIN, J. ; DATTA, A. ; JUAN, C. H. ; VENKATASUBRAMANIAN, G. . Regulatory considerations for the clinical and research use of transcranial direct current stimulation (tDCS): Review and recommendations from an expert panel. Clinical Research and Regulatory Affairs , v. 32, p. 22-35, 2015.
SHIOZAWA, P. ; SANTOS, M. ; PIOVESAN, F. ; PELLEGRINELLI, A. ; ENOKIBARA, M. ; BOCATO, M. ; CORDEIRO, QUIRINO ; FREGNI, F. ; BRUNONI, A. R. . Cerebral Blood Flow Changes After Transcranial Direct Current Stimulation for a Patient With Schizophrenia: a Case Report. The Journal of Neuropsychiatry and Clinical Neurosciences (Print) , v. x, p. x, 2014.
SHIOZAWA, PEDRO ; FREGNI, F. ; Benseñor, Isabela M. ; LOTUFO, PAULO A. ; BERLIM, MARCELO T. ; DASKALAKIS, JEFF Z. ; CORDEIRO, QUIRINO ; BRUNONI, A. R. . Transcranial direct current stimulation for major depression: an updated systematic review and meta-analysis. International Journal of Neuropsychopharmacology (Print) , v. x, p. 1-10, 2014.
BRUNONI, A. R. ; SHIOZAWA, PEDRO ; SILVA, MAILU ENOKIBARA DA ; CARVALHO, THAIS CRISTINA DE ; CORDEIRO, QUIRINO ; FREGNI, F. . Transcutaneous vagus and trigeminal nerve stimulation for neuropsychiatric disorders: a systematic review. Arquivos de Neuro-Psiquiatria (Impresso) , v. 72, p. 542-547, 2014.
BRUNONI, A. R. ; SHIOZAWA, PEDRO ; TRUONG, DENNIS ; JAVITT, DANIEL C ; ELKIS, HÉLIO ; FREGNI, F. ; Bikson, Marom . Understanding tDCS effects in schizophrenia: a systematic review of clinical data and an integrated computation modeling analysis. Expert Review of Medical Devices (Print) , v. 1, p. 1-12, 2014.
Brunoni, Andre Russowsky ; Zanao, Tamires Araujo ; Vanderhasselt, Marie-Anne ; Valiengo, Leandro ; de Oliveira, Janaina Farias ; BOGGIO, P. S. ; Lotufo, Paulo A. ; Benseñor, Isabela M. ; FREGNI, F. . Enhancement of Affective Processing Induced by Bifrontal Transcranial Direct Current Stimulation in Patients With Major Depression. Neuromodulation (Malden, Mass.) , v. 17, p. 138-142, 2014.
FECTEAU, Shirley ; AGOSTA, SARA ; HONE-BLANCHET, ANTOINE ; FREGNI, F. ; BOGGIO, P. S. ; CIRAULO, DOMENIC ; PASCUAL-LEONE, Alvaro . Modulation of smoking and decision-making behaviors with transcranial direct current stimulation in tobacco smokers: A preliminary study. Drug and Alcohol Dependence , v. n.a, p. online first, 2014.
SIMIS, MARCEL ; BRAVO, GABRIELA L. ; BOGGIO, P. S. ; DEVIDO, MICHELE ; GAGLIARDI, RUBENS J. ; FREGNI, F. . Transcranial Direct Current Stimulation in de novo Artistic Ability After Stroke. Neuromodulation (Malden, Mass.) , v. 17, p. n/a-n/a, 2014.
Lapenta, Olivia Morgan ; SIERVE, KARINA DI ; DE MACEDO, ELIZEU COUTINHO ; FREGNI, F. ; BOGGIO, P. S. . Transcranial direct current stimulation modulates ERP-indexed inhibitory control and reduces food consumption. Appetite (London. Print) , v. 83, p. 42-48, 2014.
Volz, Magdalena Sarah ; SUAREZ-CONTRERAS, VANESSA ; PORTILLA, ANDREA L. SANTOS ; ILLIGENS, BEN ; BERMPOHL, FELIX ; Fregni, Felipe . Movement observation-induced modulation of pain perception and motor cortex excitability. Clinical Neurophysiology , v. ., p. ., 2014.
HAMNER, J.W. ; VILLAMAR, MAURICIO F. ; Fregni, Felipe ; TAYLOR, J. ANDREW . Transcranial direct current stimulation (tDCS) and the cardiovascular responses to acute pain in humans. Clinical Neurophysiology , v. ., p. ., 2014.
JENSEN, MARK P. ; SHERLIN, LESLIE H. ; Fregni, Felipe ; GIANAS, ANN ; HOWE, JON D. ; HAKIMIAN, SHAHIN . Baseline Brain Activity Predicts Response to Neuromodulatory Pain Treatment. Pain Medicine (Malden, Mass.) , v. ., p. n/a-n/a, 2014.
DORUK, DENIZ ; GRAY, ZACHARY ; BRAVO, GABRIELA L. ; PASCUAL-LEONE, ALVARO ; Fregni, Felipe . Effects of tDCS on executive function in Parkinson's disease. Neuroscience Letters (Print) , v. 582, p. 27-31, 2014.
DUARTE, NATÁLIA DE ALMEIDA CARVALHO ; GRECCO, LUANDA ANDRÉ COLLANGE ; GALLI, MANUELA ; Fregni, Felipe ; OLIVEIRA, CLÁUDIA SANTOS . Effect of Transcranial Direct-Current Stimulation Combined with Treadmill Training on Balance and Functional Performance in Children with Cerebral Palsy: A Double-Blind Randomized Controlled Trial. Plos One , v. 9, p. e105777, 2014.
PASCOAL-FARIA, PAULA ; YALCIN, NILUFER ; Fregni, Felipe . Neural Markers of Neuropathic Pain Associated with Maladaptive Plasticity in Spinal Cord Injury. Pain Practice (Print) , v. ., p. n/a-n/a, 2014.
DEER, TIMOTHY R. ; MEKHAIL, NAGY ; PETERSEN, ERIKA ; KRAMES, ELLIOT ; STAATS, PETER ; POPE, JASON ; SAWERIS, YOUSSEF ; LAD, SHIVANAND P. ; DIWAN, SUDHIR ; FALOWSKI, STEVEN ; FELER, CLAUDIO ; SLAVIN, KONSTANTIN ; NAROUZE, SAMER ; Merabet, Lotfi ; BUVANENDRAN, ASOKUMAR ; Fregni, Felipe ; WELLINGTON, JOSHUA ; LEVY, ROBERT M. . The Appropriate Use of Neurostimulation: Stimulation of the Intracranial and Extracranial Space and Head for Chronic Pain. Neuromodulation (Malden, Mass.) , v. 17, p. 551-570, 2014.
GRECCO, LUANDA ANDRÉ COLLANGE ; DUARTE, NATÁLIA DE ALMEIDA CARVALHO ; MENDONÇA, MARIANA E. ; CIMOLIN, VERÔNICA ; GALLI, MANUELA ; Fregni, Felipe ; OLIVEIRA, CLAUDIA SANTOS . Transcranial direct current stimulation during treadmill training in children with cerebral palsy: A randomized controlled double-blind clinical trial. Research in Developmental Disabilities , v. 35, p. 2840-2848, 2014.
GRECCO, LUANDA ANDRÉ COLLANGE ; E MENDONÇA, MARIANA ; DUARTE, NATÁLIA A. C. ; ZANON, NELCI ; Fregni, Felipe ; OLIVEIRA, CLAUDIA SANTOS . Transcranial Direct Current Stimulation Combined with Treadmill Gait Training in Delayed Neuro-psychomotor Development. Journal of Physical Therapy Science , v. 26, p. 945-950, 2014.
KLAUSS, JAISA ; PENIDO PINHEIRO, LEON CLERES ; SILVA MERLO, BRUNA LIMA ; CORREIA SANTOS, GERSON DE ALMEIDA ; Fregni, Felipe ; NITSCHE, MICHAEL A. ; MIYUKI NAKAMURA-PALACIOS, ESTER . A randomized controlled trial of targeted prefrontal cortex modulation with tDCS in patients with alcohol dependence. International Journal of Neuropsychopharmacology (Print) , v. ., p. 1-11, 2014.
CASTILLO SAAVEDRA, LAURA ; Mendonca, Mariana ; Fregni, Felipe . Role of the primary motor cortex in the maintenance and treatment of pain in fibromyalgia. Medical Hypotheses , v. ., p. n/a, 2014.
CASTILLO SAAVEDRA, LAURA ; MORALES-QUEZADA, LEON ; DORUK, DENIZ ; ROZINSKY, JOANNA ; COUTINHO, LIVIA ; FARIA, PAULA ; PERISSINOTTI, IAGO ; WANG, QING-MEI ; Fregni, Felipe . QEEG indexed frontal connectivity effects of transcranial pulsed current stimulation (tPCS): A sham-controlled mechanistic trial. Neuroscience Letters (Print) , v. 577, p. 61-65, 2014.
EGYHAZI, RACHEL ; Fregni, Felipe ; BRAVO, GABRIELA L. ; TRINH, NHI-HA T. ; RYAN, COLLEEN M. ; SCHNEIDER, JEFFREY C. . Chronic Pain Following Physical and Emotional Trauma: The Station Nightclub Fire. Frontiers in neurology , v. 5, p. n/a, 2014.
DALL?AGNOL, LETIZZIA ; MEDEIROS, LICIANE FERNANDES ; TORRES, IRACI L.S. ; DEITOS, ALICIA ; BRIETZKE, ALINE ; Laste, Gabriela ; DE SOUZA, ANDRESSA ; VIEIRA, JÚLIA LIMA ; Fregni, Felipe ; Caumo, Wolnei . Repetitive Transcranial Magnetic Stimulation Increases the Corticospinal Inhibition and the Brain-Derived Neurotrophic Factor in Chronic Myofascial Pain Syndrome: An Explanatory Double-Blinded, Randomized, Sham-Controlled Trial. The Journal of Pain (Print) , v. 15, p. 845-855, 2014.
Azeka, E ; SAAVEDRA, LC ; FREGNI, F . Clinical research in pediatric organ transplantation. Clinics (USP. Impresso) , v. 69, p. 73-75, 2014.
SHAHBABAIE, ALIREZA ; GOLESORKHI, MEHRSHAD ; ZAMANIAN, BEHNAM ; EBRAHIMPOOR, MITRA ; KESHVARI, FATEMEH ; NEJATI, VAHID ; Fregni, Felipe ; EKHTIARI, HAMED . State dependent effect of transcranial direct current stimulation (tDCS) on methamphetamine craving. International Journal of Neuropsychopharmacology (Print) , v. 17, p. 1591-1598, 2014.
SIMIS, MARCEL ; Reidler, Jay S. ; DUARTE MACEA, DEBORA ; MORENO DUARTE, INGRID ; Wang, Xiaoen ; Lenkinski, Robert ; PETROZZA, JOHN C. ; Fregni, Felipe . Investigation of Central Nervous System Dysfunction in Chronic Pelvic Pain Using Magnetic Resonance Spectroscopy and Noninvasive Brain Stimulation. Pain Practice (Print) , v. ., p. n/a-n/a, 2014.
CONTI, CATARINE LIMA ; MOSCON, JANINE ANDRADE ; Fregni, Felipe ; NITSCHE, MICHAEL ANDREAS ; Nakamura-Palacios, Ester Miyuki . Cognitive related electrophysiological changes induced by non-invasive cortical electrical stimulation in crack-cocaine addiction. International Journal of Neuropsychopharmacology (Print) , v. ., p. 1-11, 2014.
CHIAVETTA, NOELLE M. ; MARTINS, ANA R.S. ; HENRIQUES, INÊS C.R. ; Fregni, Felipe . Differences in methodological quality between positive and negative published clinical trials. Journal of Advanced Nursing (Print) , v. 70, p. 2389-2403, 2014.
VIDOR, LILIANE ; TORRES, IRACI LS ; MEDEIROS, LICIANE ; DUSSÁN-SARRIA, JAIRO ; DALL?AGNOL, LETIZZIA ; DEITOS, ALICIA ; BRIETZKE, ALINE ; Laste, Gabriela ; ROZISKY, JOANNA R ; Fregni, Felipe ; Caumo, Wolnei . Association of anxiety with intracortical inhibition and descending pain modulation in chronic myofascial pain syndrome. BMC Neuroscience (Online) , v. 15, p. 42, 2014.
WANG, QING MEI ; Cui, Huashun ; HAN, SOO JEONG ; BLACK-SCHAFFER, RANDIE ; Volz, Magdalena Sarah ; LEE, YONG-TAE ; HERMAN, SETH ; LATIF, LYDIA ABUL ; Zafonte, Ross ; Fregni, Felipe . Combination of transcranial direct current stimulation and methylphenidate in subacute stroke. Neuroscience Letters (Print) , v. 569, p. 6-11, 2014.
SOUTO, GIÓRGIO ; BORGES, IGOR C. ; GOES, BRUNO T. ; DE MENDONÇA, MARIANA E. ; GONÇALVES, ROBERTA G. ; GARCIA, LUCAS B. ; SÁ, KATIA N. ; COUTINHO, MÁRCIO R. ; GALVÃO-CASTRO, BERNARDO ; Fregni, Felipe ; BAPTISTA, ABRAHÃO F. . Effects of tDCS-induced Motor Cortex Modulation on Pain in HTLV-1. The Clinical Journal of Pain , v. 30, p. 809-815, 2014.
TREMBLAY, SARA ; LEPAGE, JEAN-FRANÇOIS ; LATULIPE-LOISELLE, ALEX ; Fregni, Felipe ; PASCUAL-LEONE, ALVARO ; THÉORET, HUGO . The Uncertain Outcome of Prefrontal tDCS. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. 7, p. 773-783, 2014.
DI LAZZARO, VINCENZO ; DILEONE, MICHELE ; CAPONE, FIORAVANTE ; PELLEGRINO, GIOVANNI ; RANIERI, FEDERICO ; MUSUMECI, GABRIELLA ; FLORIO, LUCIA ; DI PINO, GIOVANNI ; Fregni, Felipe . Immediate and Late Modulation of Interhemipheric Imbalance With Bilateral Transcranial Direct Current Stimulation in Acute Stroke. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. 7, p. 841-848, 2014.
CARVALHO, SANDRA ; Boggio, Paulo S. ; GONÇALVES, ÓSCAR F. ; VIGÁRIO, ANA RITA ; FARIA, MARISA ; SILVA, SORAIA ; GAUDENCIO DO REGO, GABRIEL ; Fregni, Felipe ; LEITE, JORGE . Transcranial direct current stimulation based metaplasticity protocols in working memory. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. 8, p. 289, 2014.
BRUNONI ANDRE R. ; Boggio, Paulo Sergio ; Ferrucci, Roberta ; Priori, Alberto ; Fregni, Felipe . Transcranial Direct Current Stimulation: Challenges, Opportunities, and Impact on Psychiatry and Neurorehabilitation. Frontiers in Psychiatry , v. 4, p. 4:19., 2013.
VILLAMAR, M ; CONTRERAS, V ; KUNTZ, R ; FREGNI, F . The reporting of blinding in physical medicine and rehabilitation randomized controlled trials: A systematic review. Journal of Rehabilitation Medicine (Print) , v. 45, p. 6-13, 2013.
IASEMIDIS, LEONIDAS D. ; SCHACHTER, STEVEN ; Fregni, Felipe ; ILMONIEMI, RISTO . INTRODUCTION. International Journal of Neural Systems , v. 23, p. 1203003, 2013.
VILLAMAR, MAURICIO F. ; Volz, Magdalena Sarah ; Bikson, Marom ; Datta, Abhishek ; DaSilva, Alexandre F. ; Fregni, Felipe . Technique and Considerations in the Use of 4x1 Ring High-definition Transcranial Direct Current Stimulation (HD-tDCS). Journal of Visualized Experiments , v. ., p. ., 2013.
BOLOGNINI, NADIA ; SPANDRI, VIVIANA ; OLGIATI, ELENA ; Fregni, Felipe ; FERRARO, FRANCESCO ; MARAVITA, ANGELO . Long-Term Analgesic Effects of Transcranial Direct Current Stimulation of the Motor Cortex on Phantom Limb and Stump Pain: A Case Report. Journal of Pain and Symptom Management , v. ., p. ., 2013.
FARFEL, J. M. ; NITRINI, R. ; SUEMOTO, C. K. ; GRINBERG, L. T. ; FERRETTI, R. E. L. ; LEITE, R. E. P. ; TAMPELLINI, E. ; LIMA, L. ; FARIAS, D. S. ; NEVES, R. C. ; RODRIGUEZ, R. D. ; MENEZES, P. R. ; FREGNI, F. ; BENNETT, D. A. ; PASQUALUCCI, C. A. ; JACOB FILHO, W. . Very low levels of education and cognitive reserve: A clinicopathologic study. Neurology (Cleveland, Ohio) , v. 81, p. 650-657, 2013.
SCHESTATSKY, PEDRO ; MORALES-QUEZADA, LEON ; Fregni, Felipe . Simultaneous EEG Monitoring During Transcranial Direct Current Stimulation. Journal of Visualized Experiments , v. ., p. ., 2013.
WAGNER, TIM ; EDEN, URI ; RUSHMORE, JARRETT ; RUSSO, CHRISTOPHER J. ; DIPIETRO, LAURA ; Fregni, Felipe ; SIMON, STEPHEN ; ROTMAN, STEPHEN ; PITSKEL, NAOMI B. ; RAMOS-ESTEBANEZ, CIRO ; PASCUAL-LEONE, ALVARO ; GRODZINSKY, ALAN J. ; ZAHN, MARKUS ; VALERO-CABRE, ANTONI . Impact of brain tissue filtering on neurostimulation fields: A modeling study. Neuroimage (Orlando, Fla. Print) , v. ., p. ., 2013.
FIDALGO, THIAGO M. ; MORALES-QUEZADA, J. LEON ; MUZY, GUILHERME S. C. ; CHIAVETTA, NOELLE M. ; Mendonca, Mariana E. ; SANTANA, MARCUS V. B. ; GONCALVES, OSCAR F. ; BRUNONI ANDRE R. ; Fregni, Felipe . Biological Markers in Noninvasive Brain Stimulation Trials in Major Depressive Disorder. The Journal of ECT , v. ., p. 1, 2013.
Volz, Magdalena Sarah ; MEDEIROS, LICIANE F. ; TARRAGÔ, MARIA DA GRAÇA ; VIDOR, LILIANE P. ; DALL`AGNOL, LETIZZIA ; DEITOS, ALICIA ; BRIETZKE, ALINE ; ROZISKY, JOANNA R. ; RISPOLLI, BRUNA ; TORRES, IRACI L.S. ; Fregni, Felipe ; Caumo, Wolnei . The Relationship Between Cortical Excitability and Pain Catastrophizing in Myofascial Pain. The Journal of Pain (Print) , v. ., p. ., 2013.
MORENO-DUARTE, INGRID ; MORSE, LESLIE R. ; ALAM, MAHTAB ; Bikson, Marom ; Zafonte, Ross ; Fregni, Felipe . Targeted therapies using electrical and magnetic neural stimulation for the treatment of chronic pain in spinal cord injury. Neuroimage (Orlando, Fla. Print) , v. ., p. ., 2013.
Brunoni, Andre Russowsky ; KEMP, ANDREW H. ; DANTAS, EDUARDO M. ; GOULART, ALESSANDRA C. ; NUNES, MARIA ANGÉLICA ; Boggio, Paulo S. ; MILL, JOSÉ GERALDO ; Lotufo, Paulo A. ; Fregni, Felipe ; Benseñor, Isabela M. . Heart rate variability is a trait marker of major depressive disorder: evidence from the sertraline vs. electric current therapy to treat depression clinical study. International Journal of Neuropsychopharmacology (Print) , v. ., p. 1-13, 2013.
BOLOGNINI, NADIA ; OLGIATI, ELENA ; MARAVITA, ANGELO ; FERRARO, FRANCESCO ; Fregni, Felipe . Motor and parietal cortex stimulation for phantom limb pain and sensations. Pain (Amsterdam. Print) , v. 154, p. 1274-1280, 2013.
JENSEN, MARK P. ; SHERLIN, LESLIE H. ; ASKEW, ROBERT L. ; Fregni, Felipe ; WITKOP, GREGORY ; GIANAS, ANN ; HOWE, JON D. ; HAKIMIAN, SHAHIN . Effects of non-pharmacological pain treatments on brain states. Clinical Neurophysiology , v. ., p. ., 2013.
SCHESTATSKY, PEDRO ; SIMIS, MARCEL ; FREEMAN, ROY ; PASCUAL-LEONE, ALVARO ; Fregni, Felipe . Non-invasive brain stimulation and the autonomic nervous system. Clinical Neurophysiology , v. ., p. ., 2013.
ANDRADE, DAFNE C ; BORGES, IGOR ; BRAVO, GABRIELA L ; BOLOGNINI, NADIA ; Fregni, Felipe . Therapeutic time window of noninvasive brain stimulation for pain treatment: inhibition of maladaptive plasticity with early intervention. Expert Review of Medical Devices (Print) , v. 10, p. 339-352, 2013.
VALIENGO, LEANDRO ; BENSEÑOR, ISABELA MARTINS ; GOULART, ALESSANDRA C. ; DE OLIVEIRA, JANAINA FARIAS ; ZANAO, TAMIRES ARAUJO ; BOGGIO, PAULO SÉRGIO ; LOTUFO, PAULO ANDRADE ; Fregni, Felipe ; BRUNONI, ANDRÉ RUSSOWSKY . THE SERTRALINE VERSUS ELECTRICAL CURRENT THERAPY FOR TREATING DEPRESSION CLINICAL STUDY (SELECT-TDCS): RESULTS OF THE CROSSOVER AND FOLLOW-UP PHASES. Depression and Anxiety (Print) , v. 30, p. 646-653, 2013.
CANO, THAIS ; MORALES-QUEZADA, JORGE LEON ; Bikson, Marom ; Fregni, Felipe . Methods to focalize noninvasive electrical brain stimulation: principles and future clinical development for the treatment of pain. Expert Review of Neurotherapeutics , v. 13, p. 465-467, 2013.
BRUNONI, A.R. ; KEMP, A.H. ; SHIOZAWA, P. ; CORDEIRO, Q. ; VALIENGO, L.C.L. ; GOULART, A.C. ; COPRERSKI, B. ; LOTUFO, P.A. ; BRUNONI, D. ; PEREZ, A.B.A. ; FREGNI, F. ; BENSEÑOR, I.M. . Impact of 5-HTTLPR and BDNF polymorphisms on response to sertraline versus transcranial direct current stimulation: Implications for the serotonergic system. European Neuropsychopharmacology , v. ., p. ., 2013.
SHIOZAWA, PEDRO ; DA SILVA, MAILU ENOKIBARA ; CORDEIRO, QUIRINO ; Fregni, Felipe ; Brunoni, Andre Russowsky . Transcranial Direct Current Stimulation (tDCS) for the Treatment of Persistent Visual and Auditory Hallucinations in Schizophrenia: A Case Study. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. ., p. ., 2013.
SHIOZAWA, PEDRO ; DA SILVA, MAILU ENOKIBARA ; CORDEIRO, QUIRINO ; Fregni, Felipe ; Brunoni, Andre Russowsky . Transcranial direct current stimulation (tDCS) for catatonic schizophrenia: A case study. Schizophrenia Research (Print) , v. ., p. ., 2013.
VILLAMAR, MAURICIO F. ; WIVATVONGVANA, PAKORN ; PATUMANOND, JAYANTON ; Bikson, Marom ; TRUONG, DENNIS Q. ; Datta, Abhishek ; Fregni, Felipe . Focal Modulation of the Primary Motor Cortex in Fibromyalgia Using 4×1-Ring High-Definition Transcranial Direct Current Stimulation (HD-tDCS): Immediate and Delayed Analgesic Effects of Cathodal and Anodal Stimulation. The Journal of Pain (Print) , v. 14, p. 371-383, 2013.
OLIVEIRA, JANAINA F. ; ZANÃO, TAMIRES A. ; VALIENGO, LEANDRO ; Lotufo, Paulo A. ; Benseñor, Isabela M. ; Fregni, Felipe ; BRUNONI, AR. . Acute working memory improvement after tDCS in antidepressant-free patients with major depressive disorder. Neuroscience Letters (Print) , v. 537, p. 60-64, 2013.
SHIOZAWA, PEDRO ; DA SILVA, MAILU ENOKIBARA ; RAZA, ROSAMARIA ; UCHIDA, RICARDO RIYOITI ; CORDEIRO, QUIRINO ; Fregni, Felipe ; Brunoni, Andre Russowsky . Safety of Repeated Transcranial Direct Current Stimulation in Impaired Skin. The Journal of ECT , v. ., p. ., 2013.
Volz, Magdalena Sarah ; SUAREZ-CONTRERAS, VANESSA ; Mendonca, Mariana E. ; PINHEIRO, FERNANDO SANTOS ; Merabet, Lotfi B. ; Fregni, Felipe . Effects of Sensory Behavioral Tasks on Pain Threshold and Cortical Excitability. Plos One , v. 8, p. e52968, 2013.
PORTILLA, ANDREA SANTOS ; BRAVO, GABRIELA L. ; MIRAVAL, FIORELLA K. ; VILLAMAR, MAURICIO F. ; SCHNEIDER, JEFFREY C. ; RYAN, COLLEEN M. ; Fregni, Felipe . A Feasibility Study Assessing Cortical Plasticity in Chronic Neuropathic Pain Following Burn Injury. Journal of Burn Care & Research , v. 34, p. e48-e52, 2013.
FOERSTER, ÁGUIDA ; ROCHA, SÉRGIO ; WIESIOLEK, CARINE ; CHAGAS, ANNA PAULA ; MACHADO, GISELLE ; SILVA, EVELYN ; Fregni, Felipe ; MONTE-SILVA, KATIA . Site-specific effects of mental practice combined with transcranial direct current stimulation on motor learning. European Journal of Neuroscience (Print) , v. 37, p. 786-794, 2013.
DA SILVA, MORGANA CROCE ; CONTI, CATARINE LIMA ; KLAUSS, JAISA ; ALVES, LUANA GABURRO ; DO NASCIMENTO CAVALCANTE, HENRIQUE MINEIRO ; Fregni, Felipe ; NITSCHE, MICHAEL A. ; Nakamura-Palacios, Ester Miyuki . Behavioral effects of transcranial Direct Current Stimulation (tDCS) induced dorsolateral prefrontal cortex plasticity in alcohol dependence. Journal of Physiology (Paris) , v. ., p. ., 2013.
COUTO, CLÁUDIO ; DE SOUZA, IZABEL CRISTINA C. ; TORRES, IRACI L.S. ; Fregni, Felipe ; Caumo, Wolnei . Paraspinal Stimulation Combined With Trigger Point Needling and Needle Rotation for the Treatment of Myofascial Pain. The Clinical Journal of Pain , v. ., p. 1, 2013.
BRUNONI, A. R. ; SCHESTATSKY, PEDRO ; Lotufo, Paulo Andrade ; Benseñor, Isabela Martins ; FREGNI, F. . Comparison of blinding effectiveness between sham tDCS and placebo sertraline in a 6-week major depression randomized clinical trial. Clinical Neurophysiology , v. x, p. x, 2013.
BRUNONI, A. R. ; JÚNIOR, RENÉRIO FRÁGUAS ; KEMP, ANDREW H. ; LOTUFO, PAULO A. ; Benseñor, Isabela M. ; FREGNI, F. . Differential improvement in depressive symptoms for tDCS alone and combined with pharmacotherapy: an exploratory analysis from The Sertraline Vs. Electrical Current Therapy For Treating Depression Clinical Study. International Journal of Neuropsychopharmacology (Print) , v. x, p. 1-9, 2013.
BRUNONI, A. R. ; SHIOZAWA, PEDRO ; CORDEIRO, QUIRINO ; FREGNI, F. . Is sertraline plus transcranial direct current stimulation the future of effective depression treatment?. Journal of Comparative Effectiveness Research , v. 2, p. 213-215, 2013.
SHIOZAWA, PEDRO ; LEIVA, ANDRE PEREIRA G. ; CASTRO, CLAUDIA DORNFELD C. ; DA SILVA, MAILU ENOKIBARA ; CORDEIRO, QUIRINO ; FREGNI, F. ; BRUNONI, A. R. . Transcranial Direct Current Stimulation for Generalized Anxiety Disorder: A Case Study. Biological Psychiatry (1969) , v. x, p. x, 2013.
Brunoni, Andre Russowsky ; Valiengo, Leandro ; Baccaro, Alessandra ; Zanao, Tamires Araujo ; OLIVEIRA, J. F. ; Goulart, Alessandra C. ; Boggio, Paulo Sérgio ; Lotufo, Paulo Andrade ; Bensenor, Isabela M. ; FREGNI, F. . The Sertraline vs Electrical Current Therapy for Treating Depression Clinical Study: Results From a Factorial, Randomized, Controlled Trial.. JAMA (Chicago, Ill.) , v. 2013, p. 1-9, 2013.
Brunoni, A.R. ; Ferrucci, R. ; Bortolomasi, M. ; SCELZO, E. ; BOGGIO, P. S. ; FREGNI, F. ; DELL'OSSO, B. ; Giacopuzzi, M. ; ALTAMURA, A.C. ; PRIORI, A. . Interactions between transcranial direct current stimulation (tDCS) and pharmacological interventions in the Major Depressive Episode: Findings from a naturalistic study. European Psychiatry (Paris) , v. 28, p. 356-361, 2013.
LAPENTA, OLIVIA M. ; Minati, Ludovico ; FREGNI, F. ; BOGGIO, P. S. . Je pense donc je fais: transcranial direct current stimulation modulates brain oscillations associated with motor imagery and movement observation. Frontiers in Human Neuroscience , v. 7, p. 256, 2013.
FECTEAU, Shirley ; BOGGIO, P. S. ; FREGNI, F. ; PASCUAL-LEONE, Alvaro . Modulation of Untruthful Responses with Non-Invasive Brain Stimulation. Frontiers in Psychiatry , v. 3, p. Art. 97, 2013.
BOGGIO, P. S. ; Brunoni, Andre R. ; Vanderhasselt, Marie-Anne ; FREGNI, F. ; Dantas, Eduardo Miranda ; Mill, José G. ; Lotufo, Paulo A. ; Benseñor, Isabela M. . Polarity- and valence-dependent effects of prefrontal transcranial direct current stimulation on heart rate variability and salivary cortisol. Psychoneuroendocrinology , v. 38, p. 58-66, 2013.
LEITE, JORGE ; CARVALHO, SANDRA ; FREGNI, F. ; BOGGIO, P. S. ; GONÇALVES, ÓSCAR F. . The Effects of Cross-Hemispheric Dorsolateral Prefrontal Cortex Transcranial Direct Current Stimulation (tDCS) on Task Switching. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. 6, p. 660-667, 2013.
SANTOS, MICHELE DEVIDO ; GAGLIARDI, RUBENS JOSE ; MAC-KAY, ANA PAULA MACHADO GOYANO ; BOGGIO, P. S. ; LIANZA, ROBERTA ; FREGNI, F. . Transcranial direct-current stimulation induced in stroke patients with aphasia: a prospective experimental cohort study. São Paulo Medical Journal (Impresso) , v. 131, p. 422-426, 2013.
VANNESTE, SVEN ; Fregni, Felipe ; DE RIDDER, DIRK . Head-to-Head Comparison of Transcranial Random Noise Stimulation, Transcranial AC Stimulation, and Transcranial DC Stimulation for Tinnitus. Frontiers in Psychiatry , v. 4, p. n/a, 2013.
SUEMOTO, CLAUDIA KIMIE ; APOLINARIO, DANIEL ; Nakamura-Palacios, Ester Miyuki ; LOPES, LEONARDO ; PARAIZO LEITE, RENATA ELAINE ; SALES, MANUELA CASTRO ; NITRINI, RICARDO ; BRUCKI, SONIA MARIA ; MORILLO, LILIAN SHAFIROVITZ ; MAGALDI, REGINA MIKSIAN ; Fregni, Felipe . Effects of a Non-focal Plasticity Protocol on Apathy in Moderate Alzheimer's Disease: A Randomized, Double-blind, Sham-controlled Trial. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. ., p. n/a, 2013.
GRECCO, LUANDA ANDRÉ ; DUARTE, NATÁLIA DE ALMEIDA CARVALHO ; DE MENDONÇA, MARIANA ; PASINI, HUGO ; LIMA, VÂNIA LÚCIA COSTA DE CARVALHO ; FRANCO, RENATA ; DE OLIVEIRA, LUIS VICENTE ; DE CARVALHO, PAULO DE TARSO CAMILO ; CORRÊA, JOÃO CARLOS ; COLLANGE, NELCI ; SAMPAIO, LUCIANA MARIA ; GALLI, MANUELA ; Fregni, Felipe ; OLIVEIRA, CLAUDIA . Effect of transcranial direct current stimulation combined with gait and mobility training on functionality in children with cerebral palsy: study protocol for a double-blind randomized controlled clinical trial. BMC Pediatrics (Online) , v. 13, p. 168, 2013.
SIMIS, MARCEL ; ADEYEMO, BAMIDELE O. ; MEDEIROS, LICIANE F. ; MIRAVAL, FORELLA ; GAGLIARDI, RUBENS J. ; Fregni, Felipe . Motor cortex-induced plasticity by noninvasive brain stimulation. NeuroReport (Oxford) , v. 24, p. 973-975, 2013.
XU, JIANSONG ; Fregni, Felipe ; BRODY, ARTHUR L. ; RAHMAN, ARDESHIR S. . Transcranial Direct Current Stimulation Reduces Negative Affect but Not Cigarette Craving in Overnight Abstinent Smokers. Frontiers in Psychiatry , v. 4, p. n/a, 2013.
ANDRADE, A. C. ; MAGNAVITA, G. M. ; ALLEGRO, J. V. B. N. ; NETO, C. E. B. P. ; LUCENA, R. D. C. S. ; FREGNI, F. . Feasibility of Transcranial Direct Current Stimulation Use in Children Aged 5 to 12 Years. Journal of Child Neurology , v. ., p. n/a, 2013.
GULEYUPOGLU, BERKAN ; SCHESTATSKY, PEDRO ; EDWARDS, DYLAN ; Fregni, Felipe ; Bikson, Marom . Classification of methods in transcranial Electrical Stimulation (tES) and evolving strategy from historical approaches to contemporary innovations. Journal of Neuroscience Methods , v. 219, p. 297-311, 2013.
Faber M ; Vanneste S ; FREGNI, F. ; De Ridder D . Top down prefrontal affective modulation of tinnitus with multiple sessions of tDCS of dorsolateral prefrontal cortex. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. 5, p. 492-498, 2012.
Brunoni, AR ; Nitsche, M ; Bolognini N ; Bikson M ; Wagner, T ; Merabet, L ; Edwards, DJ ; Valero-Cabre, A ; Rotenberg A ; Pascual-Leone, A ; Ferrucci R ; Priori, A ; Boggio, PS ; FREGNI, F. . Clinical Research with transcranial direct current stimulation (tDCS): Challenges and future directions.. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. ., p. ., 2012.
Plow EB ; Obretenova SN ; FREGNI, F. ; Pascual-Leone, A ; Merabet, L . Comparison of Visual Field Training for Hemianopia With Active Versus Sham Transcranial Direct Cortical Stimulation.. Neurorehabilitation and Neural Repair , v. ., p. ., 2012.
Fernandes TL ; Protta TR ; FREGNI, F. ; Neto RB ; Pedrinelli A ; Camanho GL, ; Hernandez AJ. . Isokinetic muscle strength and knee function associated with double femoral pin fixation and fixation with interference screw in anterior cruciate ligament reconstruction.. Knee Surgery, Sports Traumatology, Arthroscopy , v. 20, p. 275-280, 2012.
Gladwin, Thomas E. ; den Uyl, Tess E. ; Fregni, Felipe F. ; Wiers, Reinout W. . Enhancement of selective attention by tDCS: Interaction with interference in a Sternberg task. Neuroscience Letters (Print) , v. 512, p. 33-37, 2012.
Stefani, Luciana Cadore ; Fregni, Felipe ; Torres, Iraci Lucena da Silva ; Caumo, Wolnei ; de Souza, Izabel Cristina Custodio ; Rozisky, Joanna Ripoll . BDNF as an effect modifier for gender effects on pain thresholds in healthy subjects. Neuroscience Letters (Print) , v. 514, p. 62-66, 2012.
Volz, Magdalena S. ; Fregni, Felipe ; Pinheiro, Fernando S. ; Santana, Marcus ; Mendonca, Mariana ; Cui, Huashun . Dissociation of Motor Task-Induced Cortical Excitability and Pain Perception Changes in Healthy Volunteers. Plos One , v. 7, p. e34273, 2012.
Hsing, Wu Tu ; Azevedo Neto, Raymundo S. ; Weaver, Kayleen ; Fregni, Felipe ; Imamura, Marta . Clinical Effects of Scalp Electrical Acupuncture in Stroke: A Sham-Controlled Randomized Clinical Trial. The Journal of Alternative and Complementary Medicine (New York, N.Y.) , v. 18, p. 341-346, 2012.
Reidler, Jay S. ; Mendonca, Mariana E. ; Santana, Marcus B. ; Wang, Xiaoen ; Lenkinski, Robert ; Motta, Andrea F. ; Marchand, Serge ; Latif, Lydia ; Fregni, Felipe . Effects of Motor Cortex Modulation and Descending Inhibitory Systems on Pain Thresholds in Healthy Subjects. The Journal of Pain (Print) , v. 13, p. 450-458, 2012.
Brunoni, Andre Russowsky ; Priori, Alberto ; Fregni, Felipe ; Ferrucci, Roberta ; Boggio, Paulo Sergio . Transcranial direct current stimulation for the treatment of major depressive disorder: A summary of preclinical, clinical and translational findings. Progress in Neuro-Psychopharmacology & Biological Psychiatry , v. ., p. .-., 2012.
de Brito, Christina May Moran ; GLEZER, A. ; Garcia, Ana Cristina Ferreira ; Fregni, Felipe ; Pereira, Rosa Maria Rodrigues ; Takayama, Liliam ; Battistella, Linamara Rizzo . Bone Loss in Chronic Hemiplegia: A Longitudinal Cohort Study. Journal of Clinical Densitometry , v. 2012, p. 1-5, 2012.
Laste, Gabriela ; LASTE, G ; ADACHI, L ; ROZISKY, J.R. ; Macedo, I C ; Partata, WA ; Fregni, F ; TORRES, I. L. S. ; Partata, Wania Aparecida ; Torres, Iraci L. S. ; Caumo, Wolnei ; Filho, Paulo Ricardo Marques ; Adachi, Lauren Naomi Spezia ; Rozisky, Joanna Ripoll ; Macedo, Isabel Cristina ; Fregni, Felipe . After-effects of consecutive sessions of transcranial direct current stimulation (tDCS) in a rat model of chronic inflammation. Experimental Brain Research , v. 221, p. 75-83, 2012.
Volz, Magdalena Sarah ; Volz, Theresa Sophie ; Brunoni, Andre Russowsky ; de Oliveira, João Paulo Vaz Tostes Ribeiro ; Fregni, Felipe . Analgesic Effects of Noninvasive Brain Stimulation in Rodent Animal Models: A Systematic Review of Translational Findings. Neuromodulation (Malden, Mass.) , v. 15, p. 283-295, 2012.
Bikson, Marom ; Rahman, Asif ; Datta, Abhishek ; Fregni, Felipe ; Merabet, Lotfi . High-Resolution Modeling Assisted Design of Customized and Individualized Transcranial Direct Current Stimulation Protocols. Neuromodulation (Malden, Mass.) , v. 15, p. 306-315, 2012.
Fregni, Felipe ; Merabet, Lotfi B. . Bench to Clinical Translational Applications of Noninvasive Brain Stimulation. Neuromodulation (Malden, Mass.) , v. 15, p. 281-282, 2012.
Villamar, Mauricio Fernando ; Santos Portilla, Andrea ; Fregni, Felipe ; Zafonte, Ross . Noninvasive Brain Stimulation to Modulate Neuroplasticity in Traumatic Brain Injury. Neuromodulation (Malden, Mass.) , v. 15, p. 326-338, 2012.
BATISTA-DE-OLIVEIRA, M. ; MONTE-SILVA-MACHADO, K.K. ; PAIVA, A.K. ; LIMA, H. ; FREGNI, F. ; GUEDES, R.C.A. . Favorable and unfavorable lactation modulates the effects of electrical stimulation on brain excitability: A spreading depression study in adult rats. Life Sciences (1973) , v. 91, p. 306-311, 2012.
LAPENTA, OLIVIA MORGAN ; Fregni, Felipe ; OBERMAN, LINDSAY M. ; Boggio, Paulo Sergio . Bilateral temporal cortex transcranial direct current stimulation worsens male performance in a multisensory integration task. Neuroscience Letters (Print) , v. ., p. .-., 2012.
SEHN, FRANCISLÉA ; CHACHAMOVICH, EDUARDO ; VIDOR, LILIANE PINTO ; DALL-AGNOL, LETIZZIA ; DE SOUZA, IZABEL C. CUSTÓDIO ; Torres, Iraci L. S. ; Fregni, Felipe ; Caumo, Wolnei . Cross-Cultural Adaptation and Validation of the Brazilian Portuguese Version of the Pain Catastrophizing Scale. Pain Medicine (Malden, Mass.) , v. 13, p. 1425-1435, 2012.
SPEZIA ADACHI, LAUREN NAOMI ; Caumo, Wolnei ; Laste, Gabriela ; FERNANDES MEDEIROS, LICIANE ; RIPOLL ROZISKY, JOANNA ; DE SOUZA, ANDRESSA ; Fregni, Felipe ; TORRES, IRACI L.S. . Reversal of chronic stress-induced pain by transcranial direct current stimulation (tDCS) in an animal model. Brain Research , v. 1489, p. 17-26, 2012.
Imamura, Marta ; Ozçakar L ; Fregni F ; Hsing WT ; Battistella LR . Exploring a long-term global approach for musculoskeletal ultrasound training: WORLD-MUSCULUS.. Journal of Rehabilitation Medicine (Print) , v. 44, p. 991-992, 2012.
SCHNEIDER, JEFFREY C. ; TRINH, NHI-HA T. ; SELLECK, ELIZABETH ; Fregni, Felipe ; SALLES, SARA S. ; RYAN, COLLEEN M. ; STEIN, JOEL . The Long-Term Impact of Physical and Emotional Trauma: The Station Nightclub Fire. Plos One , v. 7, p. e47339, 2012.
FARIA, PAULA ; Fregni, Felipe ; SEBASTIÃO, FERNANDO ; DIAS, ANA I. ; LEAL, ALBERTO . Feasibility of focal transcranial DC polarization with simultaneous EEG recording: Preliminary assessment in healthy subjects and human epilepsy. Epilepsy & Behavior (Print) , v. 25, p. 417-425, 2012.
DOS SANTOS, MARCOS FABIO ; LOVE, TIFFANY M. ; MARTIKAINEN, ILKKA KRISTIAN ; NASCIMENTO, THIAGO DIAS ; Fregni, Felipe ; CUMMIFORD, CHELSEA ; DEBOER, MISTY DAWN ; ZUBIETA, JON-KAR ; DASILVA, ALEXANDRE F. M. . Immediate Effects of tDCS on the μ-Opioid System of a Chronic Pain Patient. Frontiers in Psychiatry , v. 3, p. 93, 2012.
WANG, SHUANGKUN ; YUAN, JUNLIANG ; GUO, XIAOJUAN ; PENG, PENG ; GU, HUA ; NIU, SHIQIN ; Fregni, Felipe ; CHEN, ANDREW C N ; HU, WENLI . Neurochemical correlates of cognitive dysfunction in patients with leukoaraiosis: a proton magnetic resonance spectroscopy study. Neurological Research (New York) , v. 34, p. 989-997, 2012.
SCHESTATSKY, PEDRO ; JANOVIK, NATHALIA ; LOBATO, MARIA INÊS ; BELMONTE-DE-ABREU, PAULO ; SCHESTATSKY, SIDNEI ; SHIOZAWA, PEDRO ; Fregni, Felipe . Rapid therapeutic response to anodal tDCS of right dorsolateral prefrontal cortex in acute mania. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. ., p. ., 2012.
ADEYEMO, BAMIDELE O. ; SIMIS, MARCEL ; MACEA, DEBORA DUARTE ; Fregni, Felipe . Systematic Review of Parameters of Stimulation, Clinical Trial Design Characteristics, and Motor Outcomes in Non-Invasive Brain Stimulation in Stroke. Frontiers in Psychiatry , v. 3, p. ., 2012.
BRANDAO, R. A. F. S. ; FREGNI, F. ; SENA, E. P. . Utilização da estimulação magnética transcraniana como método diagnóstico em crianças: uma revisão sistemática. Revista de Ciências Médicas e Biológicas , v. 11, p. 245, 2012.
BRANDAO FILHO, R. A. ; RAMACCIOTTI, T. C. ; FREGNI, F. ; SENA, E. P. . Tratamento farmacológico da desordem temporomandibular muscular: uma revisão sistemática. Revista de Ciências Médicas e Biológicas , v. 11, p. 249, 2012.
MEDEIROS, LICIANE FERNANDES ; de Souza, Izabel Cristina Custodio ; VIDOR, LILIANE PINTO ; DE SOUZA, ANDRESSA ; DEITOS, ALÍCIA ; Volz, Magdalena Sarah ; Fregni, Felipe ; Caumo, Wolnei ; Torres, Iraci L. S. . Neurobiological Effects of Transcranial Direct Current Stimulation: A Review. Frontiers in Psychiatry , v. 3, p. 110, 2012.
Brunoni, Andre Russowsky ; ZANAO, TAMIRES ARAUJO ; Ferrucci, Roberta ; Priori, Alberto ; VALIENGO, LEANDRO ; DE OLIVEIRA, JANAINA FARIAS ; Boggio, Paulo S. ; Lotufo, Paulo A. ; Benseñor, Isabela M. ; Fregni, Felipe . Bifrontal tDCS prevents implicit learning acquisition in antidepressant-free patients with major depressive disorder. Progress in Neuro-Psychopharmacology & Biological Psychiatry , v. ., p. ., 2012.
VIDOR, LILIANE PINTO ; TORRES, IRACI L.S. ; DE SOUZA, IZABEL CRISTINA CUSTÓDIO ; Fregni, Felipe ; Caumo, Wolnei . Analgesic and Sedative Effects of Melatonin in Temporomandibular Disorders: A Double-Blind, Randomized, Parallel-Group, Placebo-Controlled Study. Journal of Pain and Symptom Management , v. ., p. ., 2012.
CESAR, A. M. R. V. ; BOGGIO, P. S. ; FREGNI, F. ; CAMPANHÃ, Camila . Neuroaccounting: um estudo experimental sobre tomada de decisão em ambientes contábeis. Advances in Scientific and Applied Accounting , v. 5, p. 27-53, 2012.
BOGGIO, P. S. ; FERRUCCI, Roberta ; Mameli, Francesca ; Martins, Débora ; Martins, Oscar ; Vergari, Maurizio ; Tadini, Laura ; Scarpini, Elio ; FREGNI, F. ; Priori, Alberto . Prolonged visual memory enhancement after direct current stimulation in Alzheimer's disease. Brain Stimulation: basic, translational and clinical research in neuromodulation , v. 5, p. 223-230, 2012.
Brunoni, AR ; Valiengo L ; Baccaro A ; Zanao TA ; de Oliveira JF ; Vieira GP ; Bueno VF ; Goulart AC ; Boggio, PS ; Lotufo PA ; Bensenor IM ; FREGNI, F. . Sertraline vs. ELectrical Current Therapy for Treating Depression Clinical Trial - SELECT TDCS: Design, rationale and objectives. Contemporary Clinical Trials , v. 32, p. 90-98, 2011.
Mahmoudi H ; Haghighi AB ; Petramfar P ; Jahanshahi S ; Salehi Z ; FREGNI, F. . Transcranial direct current stimulation: electrode montage in stroke.. Disability and Rehabilitation , v. 33, p. 1383-1388, 2011.
Horvarth JC ; Perez JM ; Forrow L ; FREGNI, F. ; Pascual-Leone, A . Transcranial magnetic stimulation: a historical evaluation and future prognosis of therapeutically relevant ethical concerns. Journal of Medical Ethics , v. 37, p. 137-143, 2011.
Tadini L ; El-Nazer R ; Brunoni, AR ; Williams JA ; Carvas M ; Boggio, PS ; Priori, A ; Pascual-Leone, A ; FREGNI, F. . Cognitive, Mood, and Electroencephalographic Effects of Noninvasive Cortical Stimulation With Weak Electrical Currents. The Journal of ECT , v. 27, p. 134-140, 2011.
FREGNI, F. ; Potvin K ; DaSilva D ; Wang X ; Lenkinski RE ; Freedman S ; Pascual-Leone, A . Clinical effects and brain metabolic correlates in non-invasive cortical neuromodulation for visceral pain. European Journal of Pain (London, England) , v. 15, p. 53-60, 2011.
Brunoni, AR ; Valim C ; FREGNI, F. . Combination of noninvasive brain stimulation with pharmacotherapy.. Expert Review of Medical Devices (Online) , v. 8, p. 31-39, 2011.
San-Juan D ; Calcáneo Jde D ; González-Aragón MF ; Bermúdez Maldonado L ; Avellán AM ; Argumosa EV ; FREGNI, F. . Transcranial direct current stimulation in adolescent and adult Rasmussen´s encephalitis.. Epilepsy & Behavior (Print) , v. 20, p. 126-131, 2011.
Bueno VF ; Brunoni, AR ; Boggio, PS ; Bensenor IM ; FREGNI, F. . Mood and cognitive effects of transcranial direct current stimulation in post-stroke depression.. Neurocase (Oxford. Print) , v. 17, p. 318-322, 2011.
Bae EH ; Theodore WH ; FREGNI, F. ; Cantello R ; Pascual-Leone, A ; Rotenberg A . An estimate of placebo effect of repetitive transcranial magnetic stimulation in epilepsy.. Epilepsy & Behavior (Print) , v. 20, p. 355-359, 2011.
Abdul Latif L ; Daud Amadera JE ; Pimentel D ; FREGNI, F. . Sample size calculation in physical medicine and rehabilitation: a systematic review of reporting, characteristics, and results in randomized controlled trials.. Archives of Physical Medicine and Rehabilitation (Print) , v. 92, p. 306-315, 2011.
Oliveira L ; FREGNI, F. . Pharmacological and electrical stimulation in chronic disorders of consciousness: new insights and future directions.. Brain Injury (London. Print) , v. 25, p. 315-327, 2011.
Brunoni, AR ; Amadera J ; Berbel B ; Volz MS ; Rizzerio BG ; FREGNI, F. . A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation.. International Journal of Neuropsychopharmacology (Print) , v. 14, p. 1133-1145, 2011.
Shin BM ; Han SJ ; Jung JH ; Kim JE ; FREGNI, F. . Effect of mild cognitive impairment on balance.. Journal of the Neurological Sciences , v. 15, p. 121-125, 2011.
Demange MK ; FREGNI, F. . Limits to clinical trials in surgical areas.. Clinics (USP. Impresso) , v. 66, p. 159-161, 2011.
Gonçalves ÓF ; Carvalho S ; Leite J ; Pocinho F ; Relvas J ; FREGNI, F. . Obsessive Compulsive Disorder as a functional interhemispheric imbalance at the thalamic level.. Medical Hypotheses , v. 77, p. 445-447, 2011.
Nakamura-Palacios EM ; de Almeida Benevides MC ; da Penha Zago- Gomes M ; de Oliveira RW ; de Vasconcellos VF ; de Castro LN ; da Silva MC ; Ramos PA ; FREGNI, F. . Auditory event-related potentials (P3) and cognitive changes induced by frontal direct current stimulation in alcoholics according to Lesch alcoholism typology.. International Journal of Neuropsychopharmacology (Print) , v. 22, p. 1-16, 2011.
Bolognini N ; Vallar G ; Casati C ; Latif LA ; El-Nazer R ; Williams JA ; Banco E ; Macea DD ; Tesio L ; Chessa C ; FREGNI, F. . Neurophysiological and behavioral effects of tDCS combined with constraint-induced movement therapy in poststroke patients.. Neurorehabilitation and Neural Repair , v. 25, p. 819-829, 2011.
Azeka, E ; FREGNI, F. ; Auler Junior JO . The past, present and future of clinical research.. Clinics (USP. Impresso) , v. 66, p. 931-932, 2011.
Brunoni, AR ; FREGNI, F. ; Pagano RL . Translational research in transcranial direct current stimulation (tDCS): a systematic review of studies in animals.. Reviews in the Neurosciences , v. 22, p. 471-481, 2011.
Mendonça ME ; Santana, Marcus B. ; Baptista AF ; Datta A ; Bikson M ; FREGNI, F. ; Araujo CP . Transcranial DC stimulation in fibromyalgia: optimized cortical target supportes by high-resolution computational models.. The Journal of Pain (Print) , v. 12, p. 610-617, 2011.
Brunoni, AR ; FREGNI, F. . Clinical trial design in non-invasive brain stimulation psychiatric research.. International Journal of Methods in Psychiatric Research (Cessou em 1996) , v. 20, p. e19-e30, 2011.
DaSilva AF ; Volz MS ; Bikson M ; FREGNI, F. . Electrode positioning and montage in transcranial direct current stimulation. Journal of Visualized Experiments , v. 51, p. 1-11, 2011.
Boggio, PS ; Ferrucci R ; Mameli F ; Martins D ; Martins O ; Vergari M ; Tadini L ; Scarpini E ; FREGNI, F. ; Priori, A . Prolonged visual memory enhancement after direct current stimulation in Alzheimer´s disease.. Brain Stimulation , v. ., p. ., 2011.
Giacobbe V ; Volpe BT ; Thickbroom GW ; FREGNI, F. ; Pascual-Leone, A ; Krebs HI ; Edwards, DJ . Reversal of TMS-induced motor twitch by training is associated with reduction in excitability of the antagonist muscle.. Journal of Neuroengineering and Rehabilitation , v. 8, p. 46, 2011.
Naeser MA ; Martin PI ; Theoret H ; Kobayashi M ; FREGNI, F. ; Nicholas M ; Tormos JM ; Steven MS ; Baker EH ; Pascual-Leone, A . TMS suppression of right pars triangularis, but not pars opercularis, improves naming in aphasia.. Brain and Language , v. 119, p. 206-213, 2011.
Leite J ; Carvalho S ; FREGNI, F. ; Gonçalves ÓF . Task-specific effects of tDCS-induced cortical excitability changes on cognitive and motor sequence set shifting performance.. Plos One , v. 6, p. e24140, 2011.
Suemoto CK ; Nitrini R ; Grinberg LT ; Ferretti RE ; Farfel JM ; Leite RE ; Menezes PR ; FREGNI, F. ; Jacob-Filho W ; Pasqualucci CA . Atherosclerosis and dementia: a cross-sectional study with pathological analysis of the carotid arteries.. Stroke (Dallas. 1970) , v. 42, p. 3614-3615, 2011.
Boggio, PS ; Valasek C ; Campanha C ; Giglio AC ; Baptista NI ; Lapenta OM ; FREGNI, F. . Non-invasive brain stimulation to assess and modulate neuroplasticity in Alzheimer´s disease.. Neuropsychological Rehabilitation (Print) , v. 21, p. 703-716, 2011.
Brunoni, AR ; Valiengo L ; Zanao TA ; de Oliveira JF ; Bensenor IM ; FREGNI, F. . Manic psychosis after sertraline and transcranial direct-current stimulation.. The Journal of Neuropsychiatry and Clinical Neurosciences (Print) , v. 23, p. E4-E5, 2011.
Ladeira A ; FREGNI, F. ; Campanha C ; Valasek C ; De Ridder D ; Brunoni, AR ; Boggio, PS . Polarity-dependent transcranial direct current stimulation effects on central auditory processing.. Plos One , v. 6, p. e25399, 2011.
Campanha C ; Minati L ; FREGNI, F. ; Boggio, PS . Responding to unfair offers made by a friend: neuroelectrical activity changes in the anterior medial prefrontal cortex.. The Journal of Neuroscience , v. 31, p. 15569-15574, 2011.
Riberto, M ; Marcon Alfieri F ; Monteiro de Benedetto Pacheco K ; Dini Leite V ; Nemoto Kaihami H ; FREGNI, F. ; Rizzo Battistella L . Efficacy of transcranial direct current stimulation coupled with a multidisciplinary rehabilitation program for the treatment of fibromyalgia.. The Open Rheumatology Journal , v. 5, p. 45-50, 2011.
Zaghi S ; Thiele B ; Pimentel D ; Pimentel T ; FREGNI, F. . Assessment and treatment of pain with non-invasive cortical stimulation.. Restorative Neurology and Neuroscience , v. ., p. ., 2011.
Wilson, ME ; FREGNI, F. ; Veras, MASM ; Dyett, J ; Shei, A ; Ribeiro GS ; David J ; Castro MC ; Segurado AC ; Ko Al ; Reis MG . Collaborative teaching and learning: a model for building capacity and partnerships to address NTDs.. PLoS Neglected Tropical Diseases , v. 5, p. e939, 2011.
FREGNI, F. . Analgesia with noninvasive electrical cortical stimulation: challenges to find optimal parameters of stimulation. Anesthesia and Analgesia , v. 5, p. 1083-1085, 2010.
Azeka, E ; FREGNI, F. . Cardiovascular research: new model of collaborative training program. Arquivos Brasileiros de Cardiologia (Impresso) , v. 95, p. 281-282, 2010.
Cohen RB ; Brunoni, AR ; Boggio, PS ; FREGNI, F. . Clinical predictors associated with duration of repetitive transcranial magnetic stimulation treatment for remission in bipolar depression: a naturalistic study. The Journal of Nervous and Mental Disease (Print) , v. 198, p. 679-681, 2010.
Boggio, PS ; Zaghi S ; Villani AB ; Fecteau, S ; Pascual-Leone, A ; FREGNI, F. . Modulation of risk-taking in marijuana users by transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC). Drug and Alcohol Dependence , v. 112, p. 220-225, 2010.
Soler MD ; Kumru H ; Pelayo R ; Vidal J ; Tormos JM ; FREGNI, F. ; Navarro X ; Pascual-Leone, A . Effectiveness of transcranial direct current stimulation and visual illusion on neuropathic pain in spinal cord injury. Brain Research , v. 133, p. 2565-2577, 2010.
Chi R ; FREGNI, F. ; Snyder A . Visual memory improved by non-invasive brain stimulation. Brain Research , v. 24, p. 168-175, 2010.
Macea DD ; Gajos K ; Daglia Calil YA ; FREGNI, F. . The efficacy of web-based cognitive behavioral interventions for chronic pain: a systematic review and meta-analysis. The Journal of Pain (Print) , v. 11, p. 917-929, 2010.
Cardoso EF ; FREGNI, F. ; Maia, F ; Melo LM ; Sato JR ; Cruz AC ; Bianchi ET ; Fernandes DB ; Monteiro ML ; Brabosa, ER ; Amaro E . Abnormal visual activation in Parkinson's disease patients. Movement Disorders , v. 15, p. 1590-1596, 2010.
Bolognini N ; FREGNI, F. ; Casati C ; Olgiati E ; Vallar G . Brain polarization of parietal cortex augments training-induced improvement of visual exploratory and attentional skills. Brain Research , v. 19, p. 76-89, 2010.
Fecteau, S ; FREGNI, F. ; Boggio, PS ; CAMPRODON, J. ; Pascual-Leone, A . Neuromodulation of decision-making in the addictive brain. Substance Use & Misuse , v. 45, p. 1766-1786, 2010.
Zaghi, S ; de Freitas Rezende L ; de Oliveira LM ; El-Nazer R ; Menning S ; Tadini L ; FREGNI, F. . Inhibition of motor cortex excitability with 15Hz transcranial alternating current stimulation (tACS). Neuroscience Letters (Print) , v. 479, p. 211-214, 2010.
Soler MD ; Kumru H ; Vidal J ; Pelayo R ; Tormos JM ; FREGNI, F. ; Navarro X ; Pascual-Leone, A . Referred sensations and neuropathic pain following spinal cord injury. The Journal of Pain (Print) , v. 150, p. 192-198, 2010.
Datta A ; Bikson M ; FREGNI, F. . Transcranial direct current stimulation in patients with skull defects and skull plates: high-resolution computational FEM study of factors altering cortical current flow. NeuroImage (Orlando, Fla. Print) , v. 52, p. 1268-1278, 2010.
Carvas M ; Imamura, M ; Hsing, WT ; Dewey- Platt L ; FREGNI, F. . An innovative method of global clinical research training using collaborative learning with Web 2.0 tools. Medical Teacher (1979. Print) , v. 32, p. 270-270, 2010.
Brunoni, AR ; Tadini L ; FREGNI, F. . Changes in clinical trials methodology over time: a systematic review of six decades of research in psychopharmacology. Plos One , v. 5, p. e9479, 2010.
Williams JA ; Pascual-Leone, A ; FREGNI, F. . Interhemispheric modulation induced by cortical stimulation and motor training. Physical Therapy , v. 90, p. 398-410, 2010.
Boggio, PS ; Campanha C ; Valasek C ; Fecteau, S ; Pascual-Leone, A ; FREGNI, F. . Modulation of decision-making in a gambling task in older adults with transcranial direct current stimulation. EJN. European Journal of Neuroscience (Online) , v. 31, p. 593-597, 2010.
FREGNI, F. ; Imamura, M ; Chien HF ; Lew HL ; Boggio, PS ; Kaptchuk TJ ; Ribeiro M ; Hsing, WT ; Battistella LR ; Furlan A . International placebo symposium working group. Challenges and recommendations for placebo controls in randomized trials in physical and rehabilitation medicine: a report of the international placebo symposium working group. American Journal of Physical Medicine & Rehabilitation , v. 89, p. 160-172, 2010.
Cogiamanian F ; Brunoni, AR ; Boggio, PS ; FREGNI, F. ; Ciocca M ; Priori, A . Non-invasive brain stimulation for the management of arterial hypertension. Medical Hypotheses , v. 74, p. 332-336, 2010.
Boggio, PS ; Rocha M ; Oliveira MO ; Fecteau, S ; Cohen RB ; Campanha C ; Ferreira-Santos E ; Meleiro A ; Corchs F ; Zaghi S ; Pascual-Leone, A ; FREGNI, F. . Noninvasive brain stimulation with high-frequency and low-intensity repetitive transcranial magnetic stimulation treatment for posttraumatic stress disorder. The Journal of Clinical Psychiatry , v. 71, p. 992-999, 2010.
Zaghi, S ; Acar M ; Hultgren B ; Boggio, PS ; FREGNI, F. . Noninvasive brain stimulation with low-intensity electrical currents: putative mechanisms of action for direct and alternating current stimulation. The Neuroscientist (Baltimore, Md.) , v. 16, p. 285-307, 2010.
Brunoni, AR ; FREGNI, F. . Accelerating response to antidepressant treatment in depression: a review and clinical suggestions.. Progress in Neuro-Psychopharmacology & Biological Psychiatry , v. 34, p. 437-438, 2010.
Brunoni, AR ; Teng CT ; Correa, CF ; Imamura, M ; Brasil-Neto JP ; Boechat R ; Rosa M ; Caramelli P ; Cohen RB ; Del Porto JA ; Boggio, PS ; FREGNI, F. . Neuromodulation approaches for the treatment of major depression: challenges and recommendations from a working group meeting.. Arquivos de Neuro-Psiquiatria (Impresso) , v. 68, p. 433-451, 2010.
Bashir S ; Mizrahi I ; Weaver K ; FREGNI, F. ; Pascual-Leone, A . Assessment and modulation of neural plasticity in rehabilitation with transcranial magnetic stimulation.. American Journal of Physical Medicine & Rehabilitation , v. 2, p. s253-268, 2010.
EDELMUTH, R. C. L. ; Battistella, Linamara ; FREGNI, F. ; Nitsche, Michael A . Why do some promising brain-stimulation devices fail the next steps of clinical development?. Expert Review of Medical Devices (Print) , v. 7, p. 67-97, 2010.
Alappat JJ ; Zaghi, S ; Lima, MC ; FREGNI, F. . Motor cortex stimulation for chronic pain: systematic review and meta-analysis of the literature. Neurology (Cleveland, Ohio) , v. 24, p. 577-577, 2009.
Imamura, M ; Hsing, WT ; Platt LD ; FREGNI, F. . How to develop research capacity using a collaborative training approach: the International Society pf Physical and Rehabilitation Medicine (ISPRM) international training program experience. Journal of Rehabilitation Medicine , v. 41, p. 295-296, 2009.
Williams JA ; Colton K ; FREGNI, F. ; Pascual-Leone, A ; Alexander M . Feasibility of a home constraint-induced movement therapy for hand weakness after stroke. Journal of Rehabilitation Medicine , v. 41, p. 92-93, 2009.
Boggio, PS ; Carreiro LR ; FREGNI, F. . Cortical stimulation with weak electrical currents for cognitive modulation in attention deficit hyperactivity disorder. Medical Hypotheses , v. 72, p. 613-614, 2009.
Freitas C ; FREGNI, F. ; Pascual-Leone, A . Meta-analysis of the effects of repetitive transcranial magnetic stimulation (rTMS) on negative and positive symptoms in schizophrenia. Schizophrenia Research , v. 1-3, p. 11-24, 2009.
Boggio, PS ; Zaghi, S ; FREGNI, F. . Modulation of emotions associated with images of human pain using anodal transcranial direct current stimulation (tDCS). Neuropsychologia (Oxford) , v. 1, p. 212-217, 2009.
Boggio, PS ; Liguori P ; Sultani N ; Rezende L ; Fecteau, S ; FREGNI, F. . Cumulative priming effects of cortical stimulation on smoking cue-induced craving. Neuroscience Letters , v. 1, p. 19619607, 2009.
Boggio, PS ; Macedo, EC ; Schwartzman JS ; Brunoni, AR ; Teixeira MC ; FREGNI, F. . Transcranial direct current stimulation: a novel approach to control hyperphagia. Journal of Child Neurology , v. 24, p. 642-643, 2009.
Cardoso EF ; Maia, F ; FREGNI, F. ; Myczkowski, ML ; Melo LM ; Sato JR ; Marcolin, MA ; Rigonatti, SP ; Cruz AC ; Brabosa, ER ; Amaro E . Depression in Parkinson's disease: convergence from voxel-based morphometry and functional magnetic resonance imaging in the limbic thalamus. NeuroImage (Orlando) , v. 15, p. 467-472, 2009.
Williams JA ; Imamura, M ; FREGNI, F. . Updates on the use of non-invasive brain stimulation in physical and rehabilitation medicine. Journal of Rehabilitation Medicine , v. 41, p. 305-311, 2009.
Nitsche, M ; Boggio, PS ; FREGNI, F. ; Pascual-Leone, A . Treatment of depression with transcranial direct current stimulation (tDCS): A Review. Experimental Neurology , v. 1, p. 19348793, 2009.
Murphy DN ; Boggio, PS ; FREGNI, F. . Transcranial direct current stimulation as a therapeutic tool for the treatment of major depression: insights from past and recent clinical studies. Current Opinion in Psychiatry , v. 22, p. 306-311, 2009.
Boggio, PS ; FREGNI, F. ; Valasek C ; Ellwood S ; Chi R ; Gallate J ; Pascual-Leone, A ; Snyder A . Temporal lobe cortical electrical stimulation during the encoding and retrieval phase reduces false memories. PloS one (San Francisco, CA) , v. 4, p. e4959-e4959, 2009.
Brunoni, AR ; Lopes M ; Kaptchuk TJ ; FREGNI, F. . Placebo response of non-pharmacological and pharmacological trials in major depression: a systematic review and meta-analysis. PloS one (San Francisco, CA) , v. 4, p. e4824-e4824, 2009.
Bolognini N ; Pascual-Leone, A ; FREGNI, F. . Using non-invasive brain stimulation to augment motor training-induced plasticity. Journal of Neuroengineering and Rehabilitation , v. 17, p. 19292910, 2009.
FREGNI, F. ; Liguori P ; Fecteau, S ; Nitsche, M ; Pascual-Leone, A ; Boggio, PS . Cortical Stimulation of the Prefrontal Cortex With Transcranial DC Stimulation reduces Smoking Cue-Provoked Craving: A Randomized, Sham-Controlled Study. Journal of Clinical Psychiatry , v. 1, p. 32-40, 2008.
Boggio, PS ; Sultani N ; Fecteau, S ; Merabet, L ; Pascual-Leone, A ; FREGNI, F. . Prefrontal cortex modulation using transcranial DC stimulation reduces alcohol craving: A double-blind, sham-controlled study. Drug and Alcohol Dependence , v. 92, p. 55-60, 2008.
Rigonatti, SP ; Boggio, PS ; Myczkowski, ML ; Otta E ; Fiquer JT ; Ribeiro RB ; Nitsche, M ; Pascual-Leone, A ; FREGNI, F. . Transcranial direct stimulation and fluoxetine for the treatment of depression. European Psychiatry (Paris) , v. 1, p. 74-76, 2008.
Cappelletti M ; FREGNI, F. ; Shapiro K ; Pascual-Leone, A ; Caramazza A . Processing Nouns and Verbs in the Left Frontal Cortex: A Transcranial Magnetic Stimulation Study. Journal of Cognitive Neuroscience , v. 4, p. 707-720, 2008.
Rosa, MA ; Rosa, MO ; Belegarde, IM ; Bueno, CR ; FREGNI, F. . Recovery after ECT: comparison of propofol, etomidate and thiopental. Revista Brasileira de Psiquiatria (São Paulo) , v. 2, p. 149-151, 2008.
FREGNI, F. . Towards novel treatments for pediatric stroke: is transcranial magnetic stimulation beneficial?. Lancet Neurology , v. 6, p. 472-473, 2008.
Brunoni, AR ; Boggio, PS ; FREGNI, F. . Can the "yin and yang" BDNF hypothesis be used to predict the effects of rTMS treatment in neuropsychiatry?. Medical Hypotheses , v. 2, p. 279-282, 2008.
Wu, A ; FREGNI, F. ; Simon, DK ; Deblieck, C ; Pascual-Leone, A . Noninvasive brain stimulation for Parkinson's diseasse and dystonia. Neurotherapeutics (American Society for Experimental NeuroTherapeutics) , v. 2, p. 345-361, 2008.
Edwards, DJ ; FREGNI, F. . Modulating the healthy and affected motor cortex with repetitive transcranial magnetic stimualtion in stroke: development of new strategies for neurorehabilitation. NeuroRehabilitation (Reading) , v. 1, p. 3-14, 2008.
FREGNI, F. ; Orsati F ; Pedrosa, W ; Fecteau, S ; Tome, FA ; Nitsche, M ; Macedo, EC ; Pascual-Leone, A ; Boggio, PS . Transcranial direct current stimulation of the prefrontal cortex modulates the desire for specific foods. Appetite , v. 1, p. 34-41, 2008.
Zago, S ; Ferrucci R ; FREGNI, F. ; Priori, A . Bartholow, Sciamanna, Alberti: Pioneers in the Electrical Stimulation of the exposed human cerebral cortex. The Neuroscientist (Baltimore) , v. 00, p. 00-00, 2008.
Wagner, T ; Eden, U ; FREGNI, F. ; Valero-Cabre, A ; Ramos-Estebanez C ; Pronio-Stelluto, V ; Grodzinsky, A ; Zahn, M ; Pascual-Leone, A . Transcranial magnetic stimulation and brain atrophy: a computer-based human brain model study. Experimental Brain Research , v. 4, p. 539-550, 2008.
Jensen, MP ; Hakimian, S ; Sherlin, LH ; FREGNI, F. . New insights into neuromodulatory approaches for the treatment of pain. Journal of Pain , v. 3, p. 193-199, 2008.
Cecilio, SB ; Zaghi, S ; Cecilio, LB ; Correa, CF ; FREGNI, F. . Exploring a novel therapeutic approach with noninvasive cortical stimulation for vulvodynia. American Journal of Obstetrics and Gynecology , v. 199, p. e6-e7, 2008.
Zanardi, R ; Barbini, B ; Rossini, D ; Bernasconi, A ; FREGNI, F. ; Padberg, F ; Rossi, S ; Wirz-Justice, A ; Terman, M ; Martiny, K ; Bersani, G ; Hariri, AR ; Pezawas, L ; Roiser, JP ; Bertolino, A ; Calabrese, G ; Magri, L ; Benedetti, F ; Pontiggia, A . New perspectives on techniques for the clinical psychiatrist: Brain stimulation, chronobiology and psychiatric brain imaging. Psychiatry and Clinical Neurosciences , v. 6, p. 627-637, 2008.
Boggio, PS ; Rocha RR ; SILVA, M. T. A. ; FREGNI, F. . Differential modulatory effects of transcranial direct current stimulation on a facial expression go-no-go task in males and females. Neuroscience Letters , v. 2-3, p. 101-105, 2008.
Passos Mdo C ; Duro D ; FREGNI, F. . CNS or classic drugs for the treatment of pain in functional dyspesia? A systematic review and meta-analysis of the literature. Pain Physician , v. 5, p. 597-609, 2008.
Imamura, M ; Imamura ST ; Kaziyama HH ; Targino RA ; Hsing, WT ; de Souza LP ; Cutait MM ; FREGNI, F. ; Camanho GL . Impact of nervous system hyperalgesia on pain, disability, and quality of life in patients with knee osteoarthristis: a controlled analysis. Arthritis and Rheumatism , v. 10, p. 1424-1431, 2008.
Bajwa S ; Bermpohl, F ; Rigonatti, SP ; Pascual-Leone, A ; Boggio, PS ; FREGNI, F. . Impaired interhemispheric interactions in patients with major depression. The Journal of Nervous and Mental Disease , v. 9, p. 671-677, 2008.
Brunoni, AR ; Lopes M ; FREGNI, F. . A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. International Journal of Neuropsychopharmacology , v. 8, p. 1169-1180, 2008.
Boggio, PS ; Zaghi, S ; Lopes M ; FREGNI, F. . Modulatory effects of anodal transcranial direct current stimulation on perception and pain thresholds in healthy volunteers. European Journal of Neurology , v. 10, p. 1124-1130, 2008.
Bermpohl, F ; Pascual-Leone, A ; Amedi, A ; Merabet, LB ; FREGNI, F. ; Wrase J ; Schlagenhauf F ; Bauer M ; Heinz A ; Schlaug G ; Northoff, G . Novelty seeking modulates medial prefrontal activity during the anticipation of emotional stimuli. Psychiatry Research , v. 1, p. 81-85, 2008.
Wagner, T ; FREGNI, F. ; Fecteau, S ; Grodzinsky, A ; Zahn, M ; Pascual-Leone, A . Transcranial direct current stimulation: A computer-based human model study. NeuroImage (Orlando) , v. 35, p. 1113-1124, 2007.
Ramos-Estebanez C ; Merabet, LB ; Machii K ; FREGNI, F. ; Thut, G ; Wagner, T ; Romei V ; Amedi, A ; Pascual-Leone, A . Visual phosphene perception modulated by subthreshold crossmodal sensory stimulation. The Journal of Neuroscience , v. 27, p. 4178-4181, 2007.
Rosa, MA ; Rosa, MO ; Marcolin, MA ; FREGNI, F. . Cardiovascular effects of anesthesia in ECT: a randomized, double-blind comparison of etomidate, propofol, and thiopental. The Journal of Electroconvulsive Therapy , v. 23, p. 6-8, 2007.
FREGNI, F. ; Liebetanz, D ; SILVA, K. K. M. ; Oliveira MB ; Amancio-dos-Santos, A ; Nitsche, M ; Pascual-Leone, A ; Guedes RC . Effects of transcranial direct current stimulation coupled with repetitive electrical stimulation on cortical spreading depression. Experimental Neurology , v. 204, p. 462-466, 2007.
Nair DG ; Hutchinson S ; FREGNI, F. ; Alexander M ; Pascual-Leone, A ; Schlaug G . Imaging correlates of motor recovery from cerebral infarction and their physiological significance in well-recovered patients. NeuroImage (Orlando) , v. 34, p. 253-263, 2007.
Gross M ; Nakamura L ; Pascual-Leone, A ; FREGNI, F. . Has repetitive transcranial magnetic stimulation (rTMS) treatment for depression improved? A systematic review and meta-analysis comparing the recent vs. the earlier rTMS studies. Acta Psychiatrica Scandinavica , v. 116, p. 165-73, 2007.
FREGNI, F. ; Pascual-Leone, A . Technology insight: noninvasive brain stimulation in neurology-perspectives on the therapeutic potential of rTMS and tDCS. Nature Clinical Practice Neurology , v. 3, p. 383-393, 2007.
Valle, AC ; Dionisio K ; Pitskel N ; Pascual-Leone, A ; Orsati F ; Ferreira, MJ ; Boggio, PS ; Lima, MC ; Rigonatti, SP ; FREGNI, F. . Low and high frequency repetitive transcranial magnetic stimulation for the treatment of spasticity. Developmental Medicine and Child Neurology , v. 49, p. 534, 2007.
Fecteau, S ; Pascual-Leone, A ; Zald D ; Liguori P ; Theoret H ; Boggio, PS ; FREGNI, F. . Activation of prefrontal cortex by transcranial direct current stimulation reduces appetite for risk during ambiguous decision making. The Journal of Neuroscience , v. 27, p. 6212-6218, 2007.
Boggio, PS ; Nunes A ; Rigonatti, SP ; Nitsche, M ; Pascual-Leone, A ; FREGNI, F. . Repeated sessions of noninvasive brain DC stimulation is associated with motor function improvement in stroke patients. Restorative Neurology and Neuroscience , v. 25, p. 123-129, 2007.
Alonso-Alonso M ; FREGNI, F. ; Pascual-Leone, A . Brain stimulation in poststroke rehabilitation. Cerebrovascular Diseases (Basel) , v. 24, p. 157-166, 2007.
FREGNI, F. ; Pascual-Leone, A ; Freedman S . Pain in chronic pancreatitis: a salutogenic mechanism or a maladaptive brain response?. Pancreatology , v. 7, p. 411-422, 2007.
Cappelletti M ; Bart H ; FREGNI, F. ; Speike E. ; Pascual-Leone, A . rTMS over the intraparietal sulcus disrupts numerosity processing. Experimental Brain Research , v. 179, p. 631-642, 2007.
Gross M ; Nakamura L ; Pascual-Leone, A ; FREGNI, F. . Diminishing risk-taking behavior by modulating activity in the prefrontal cortex: a direct current stimulation study. The Journal of Neuroscience , v. 27, p. 12500-12505, 2007.
Roizenblatt S ; FREGNI, F. ; Gimenes R ; Wetzel T ; Rigonatti, SP ; Tufik S ; Boggio, PS ; Valle, AC . Site-specific effects of transcranial direct current stimulation on sleep and pain in fibromyalgia: a randomized, sham-controlled study. Pain Practice , v. 7, p. 297-306, 2007.
Edwards, DJ ; Mastaglia, FL ; Byrnes, ML ; FREGNI, F. ; Pascual-Leone, A ; Thickbroom, GW . Supraspinal inputs reduce corticomotor excitability during passive movement: evidence from a pure sensory stroke. Restorative Neurology and Neuroscience , v. 25, p. 527-533, 2007.
Kuo, MF ; Grosch, J ; FREGNI, F. ; Paulus, W ; Nitsche, M . Focusing effect of acetylcholine on neuroplasticity in the human motor cortex. The Journal of Neuroscience , v. 52, p. 14442-14447, 2007.
Fecteau, S ; Knoch, D ; FREGNI, F. ; Sultani N ; Boggio, PS ; Pascual-Leone, A . Diminishing risk-taking behavior by modulation activity in the prefrontal cortex: a direct current stimulation study. The Journal of Neuroscience , v. 46, p. 12500-12505, 2007.
Marcondes, R ; FREGNI, F. ; Pascual-Leone, A . Tinnitus and brain activation: insights from transcranial magnetic stimulation. Ear, Nose, & Throat Journal , p. 233-234, 2006.
FREGNI, F. ; Boggio, PS ; Valle, AC ; Otachi, PT ; Thut, G ; Rigonatti, SP ; Marcolin, MA ; Fecteau, S ; Pascual-Leone, A ; Valente, KD . Homeostatic effects of plasma valproate levels on corticospinal excitability changes induced by 1Hz rTMS in patients with juvenile myoclonic epilepsy. Clinical Neurophysiology , v. 25, 2006.
Patrizzi, F ; Freedman S ; Pascual-Leone, A ; FREGNI, F. . Novel therapeutic approaches to the treatment of chronic abdominal visceral pain. Scientific World Journal, v. 18, n.6, p. 472-490, 2006.
FREGNI, F. ; Pascual-Leone, A . Hand motor recovery after stroke: tuning the orchestra to improve hand motor function. Cognitive and Behavioral Neurology , v. 19, n.1, p. 21-33, 2006.
Boggio, PS ; FREGNI, F. ; Rigonatti, SP ; Marcolin, MA ; SILVA, M. T. A. . Transcranial magnetic stimulation in neuropsychology: new horizons for brain research. Revista Brasileira de Psiquiatria (São Paulo) , v. 28, n.1, p. 44-49, 2006.
FREGNI, F. ; Boggio, PS ; Wagner, T ; Rigonatti, SP ; Castro, AW ; Souza, DR ; Riberto, M ; Freedman S ; Nitsche, M ; Pascual-Leone, A . A sham-controlled, phase II trial of transcranial direct current stimulation for the treatment of central pain in traumatic spinal cord injury. Pain (Amsterdam) , p. 197-209, 2006.
FREGNI, F. ; Boggio, PS ; Nitsche, M ; Marcolin, MA ; Rigonatti, SP ; Pascual-Leone, A . Treatment of major depression with transcranial direct current stimulation. Bipolar Disorders , v. 8, n.2, p. 203-204, 2006.
FREGNI, F. ; Thome-Souza, S ; Nitsche, M ; Freedman S ; Valente, KD ; Pascual-Leone, A . A controlled clinical trial of cathodal DC polarization in patients with refractory epilepsy. Epilepsia (Copenhagen) , v. 47, n.2, p. 335-342, 2006.
Wagner, T ; FREGNI, F. ; Eden, U ; Ramos-Estebanez C ; Grodzinsky, A ; Pascual-Leone, A . Transcranial magnetic stimulation and stroke: a computer-based human model study. NeuroImage (Orlando) , v. 30, n.3, p. 857-870, 2006.
Liebetanz, D ; FREGNI, F. ; Monte-Silva KK ; Oliveira MB ; Amancio-dos-Santos, A ; Nitsche, M ; Guedes RC . After-effects of transcranial direct current stimulation (tDCS) on cortical spreading depression. Neuroscience Letters , p. 85-90, 2006.
Dias AE ; Brabosa, ER ; Coracini, K ; Maia, F ; Marcolin, MA ; FREGNI, F. . Effects of repetitive transcranial magnetic stimulation on voice and speech in Parkinson's disease. Acta Neurologica Scandinavica , v. 113, n.2, p. 92-99, 2006.
Bermpohl, F ; FREGNI, F. ; Boggio, PS ; Thut, G ; Northoff, G ; Otachi, PT ; Rigonatti, SP ; Marcolin, MA ; Pascual-Leone, A . Effect of low-frequency transcranial magnetic stimulation on an affective go/no-go task in patients with major depression: role of stimulation site and depression severity. Psychiatry Research , v. 141, n.1, p. 1-13, 2006.
FREGNI, F. ; Pascual-Leone, A . Repetitive transcranial magnetic stimulation for the treatment of depression. Journal of Psychiatry & Neuroscience , v. 30, n.6, p. 434-435, 2006.
Bermpohl, F ; Pascual-Leone, A ; Amedi, A ; Merabet, LB ; FREGNI, F. ; Alsop D ; Schlaug G ; Northoff, G . Dissociable networks for the expectancy and perception of emotional stimuli in the human brain. NeuroImage (Orlando) , v. 30, n.2, p. 588-600, 2006.
FREGNI, F. ; Marcondes, R ; Boggio, PS ; Marcolin, MA ; Rigonatti, SP ; Sanchez TG ; Nitsche, M ; Pascual-Leone, A . Transient tinnitus suppression induced by repetitive transcranial magnetic stimulation and transcranial direct current stimulation. European Journal of Neurology , v. 9, p. 996-1001, 2006.
Rosa, MA ; Gattaz, WF ; Pascual-Leone, A ; FREGNI, F. ; Rosa, MO ; Rumi, DO ; Myczkowski, ML ; SILVA, M. F. ; Mansur, CGS ; Rigonatti, SP ; TEIXEIRA, M. J. ; Marcolin, MA . Comparison of repetitive transcranial magnetic stimulation and electroconvulsive therapy in unipolar non-psychotic refractory depression: a randomized, single-blind study. International Journal of Neuropsychopharmacology , v. 21, p. 1-10, 2006.
CONFORTO, A. B. ; FREGNI, F. ; Puglia P Jr ; Leite, CC ; Yamamoto, FI ; Coracini, K ; Scaff, M . Comparison between digital subtraction angiography and magnetic resonance angiography in investigation of nonlacunar ischemic stroke in young patients: preliminary results. Arquivos de Neuro-Psiquiatria , v. 64, p. 353-358, 2006.
Carey JR ; FREGNI, F. ; Pascual-Leone, A . rTMS combined with motor learning training in healthy subjects. Restorative Neurology and Neuroscience , v. 24, p. 191-199, 2006.
FREGNI, F. ; Boggio, PS ; Nitsche, M ; Rigonatti, SP ; Pascual-Leone, A . Cognitive effects of repeated sessions of transcranial direct current stimulation in patients with depression. Depression and Anxiety , v. x, p. 01-x, 2006.
Boggio, PS ; Ferrucci R ; Rigonatti, SP ; Covre P ; Nitsche, M ; Pascual-Leone, A ; FREGNI, F. . Effects of transcranial direct current stimulation on working memory in patients with Parkinson's disease. Journal of the Neurological Sciences , v. x, p. 01-x, 2006.
FREGNI, F. ; Boggio, PS ; Santos, CM ; Lima, MC ; VIEIRA, A. L. ; Rigonatti, SP ; SILVA, M. T. A. ; Brabosa, ER ; Nitsche, M ; Pascual-Leone, A . Noninvasive cortical stimulation with transcranial direct current stimulation in Parkinson's disease. Movement Disorders , v. x, p. 01-0, 2006.
FREGNI, F. ; Boggio, PS ; Valle, AC ; Rocha RR ; Duarte J ; Ferreira, MJ ; Wagner, T ; Fecteau, S ; Rigonatti, SP ; Riberto, M ; Freedman S ; Pascual-Leone, A . A sham-controlled trial of a 5-day course of repetitive transcranial magnetic stimulation of the unaffected hemisphere in stroke patients. Stroke , v. 37, p. 2115-2122, 2006.
Boggio, PS ; Castro LO ; Savagin EA ; Braite R ; Cruz VC ; Rocha RR ; Rigonatti, SP ; SILVA, M. T. A. ; FREGNI, F. . Enhancement of non-dominant hand motor function by anodal transcranial direct current stimulation. Neuroscience Letters , v. 404, p. 232-236, 2006.
FREGNI, F. ; Ono CR ; Santos, CM ; Bermpohl, F ; Buchpiguel C ; Brabosa, ER ; Marcolin, MA ; Pascual-Leone, A ; Valente, KD . Effects of antidepressant treatment with rTMS and fluoxetine on brain perfusion in PD. Neurology (Cleveland, Ohio) , v. 66, p. 1629-1637, 2006.
Marcolin, MA ; SOUZA FILHO, J. L. ; TEIXEIRA, M. J. ; FREGNI, F. . Transient visual changes associated with repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex in cases of major depression. Revista Brasileira de Psiquiatria (São Paulo) , v. 28, p. 251-256, 2006.
FREGNI, F. ; Marcolin, MA ; Myczkowski, ML ; AMIAZ, R ; HASEY, G ; Rumi, DO ; Rosa, MA ; Rigonatti, SP ; CAMPRODON, J. ; WALPOTH, M. ; HEASLIP, J. ; GRUNHAUS, L. ; Pascual-Leone, A . Predictors of antidepressant response in clinical trials of transcranial magnetic stimulation. International Journal of Neuropsychopharmacology , v. 9, p. 641-654, 2006.
FREGNI, F. ; Gimenes R ; Valle, AC ; Ferreira, MJ ; Rocha RR ; Natalle L ; Bravo R. ; Rigonatti, SP ; Freedman S ; Nitsche, M ; Pascual-Leone, A ; Boggio, PS . A randomized, sham-controlled, proof of principle study of transcranial direct current stimulation for the treatment of pain in fibromyalgia. Arthritis and Rheumatism , v. 54, p. 3988-3998, 2006.
Theoret H ; Halligan E ; Kobayashi M ; FREGNI, F. ; Tager-Flusberg, H ; Pascual-Leone, A . Impaired motor facilitation during action observation in individuals with autism spectrum disorder. Current Biology , v. 8, p. 84-85, 2005.
Rumi, DO ; Gattaz, WF ; Rigonatti, SP ; Rosa, MA ; FREGNI, F. ; Odebrecht, M ; Mansur, CGS ; Myczkowski, ML ; Moreno RA ; Marcolin, MA . Transcranial Magnetic Stimulation Accelerates the Antidepressant Effect of Amytriptiline in Severe Depression. Biological Psychiatry , v. 15, p. 162-166, 2005.
FREGNI, F. ; Thome-Souza, S ; Bermpohl, F ; Marcolin, MA ; Herzog A ; Pascual-Leone, A ; Valente, KD . Antiepileptic Effects of Repetitive Transcranial Magnetic Stimulation in Patients with Cortical Malformations: An EEG and Clinical Study. Stereotactic and Functional Neurosurgery , v. 30, p. 57-62, 2005.
FREGNI, F. ; Mansur, CGS ; Boggio, PS ; Riberto, M ; Gallucci, JN ; Santos, CM ; Wagner, T ; Rigonatti, SP ; Marcolin, MA ; Pascual-Leone, A . A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients. Neurology (Cleveland, Ohio) , v. 24, p. 1802-1804, 2005.
Boggio, PS ; FREGNI, F. ; Bermpohl, F ; Rosa, MA ; Rumi, DO ; Brabosa, ER ; Pascual-Leone, A ; Rigonatti, SP ; Marcolin, MA ; SILVA, M. T. A. . Effect of repetitive TMS and fluoxetine on cognitive function in patients with Parkinson's disease and concurrent depression. Movement Disorders , v. 13, p. 1178-1184, 2005.
FREGNI, F. ; SILVA, K. K. M. ; Oliveira MB ; Freedman S ; Pascual-Leone, A ; Guedes RC . Lasting accelerative effects of 1 Hz and 20 Hz electrical stimulation on cortical spreading depression: relevance for clinical applications of brain stimulation. European Journal of Neuroscience , v. 21, p. 2278-2284, 2005.
FREGNI, F. ; Boggio, PS ; Nitsche, M ; Pascual-Leone, A . Transcranial direct current stimulation. British Journal of Psychiatry , p. 446-447, 2005.
Bermpohl, F ; FREGNI, F. ; Boggio, PS ; Thut, G ; Northoff, G ; Otachi, PT ; Rigonatti, SP ; Marcolin, MA ; Pascual-Leone, A . Left prefrontal repetitive transcranial magnetic stimulation impairs performance in affective go/no-go task. NeuroReport (Oxford) , v. 25, p. 615-619, 2005.
FREGNI, F. ; Naeser MA ; Martin PI ; Nicholas M ; Baker E ; Seekins H ; Kobayashi M ; Theoret H ; Maria-Tormos, J ; Pascual-Leone, A . Improved picture naming in chronic aphasia after TMS to part of right Broca's area: an open-protocol study. Brain and Language , v. 93, p. 95-105, 2005.
FREGNI, F. ; Pascual-Leone, A ; Theoret H ; CLARK, D. ; WAGNER, A. D. . Transient disruption of ventrolateral prefrontal cortex during verbal encoding affects subsequent memory performance. Journal of Neurophysiology , v. 94, p. 688-698, 2005.
FREGNI, F. ; Boggio, PS ; Mansur, CGS ; Wagner, T ; Ferreira, MJ ; Rigonatti, SP ; Marcolin, MA ; Freedman S ; Nitsche, M ; Pascual-Leone, A . Transcranial direct current stimulation of the unaffected hemisphere in stroke patients. NeuroReport (Oxford) , p. 1551-1555, 2005.
FREGNI, F. ; Schachter, SC ; Pascual-Leone, A . Transcranial magnetic stimulation treatment for epilepsy: Can it also improve depression and vice versa?. Epilepsy & Behavior , p. 182-189, 2005.
Pascual-Leone, A ; Amedi, A ; FREGNI, F. ; Merabet, LB . The plastic human brain cortex. Annual Review of Neuroscience , p. 377-401, 2005.
Naeser MA ; Martin PI ; Nicholas M ; Baker E ; Seekins H ; Helm-Estabrooks, N ; Cayer-Meade C ; Theoret H ; FREGNI, F. ; Pascual-Leone, A . Improve naming after TMS treatment in a chronic, global aphasia patient - case report. Neurocase (Oxford) , p. 182-193, 2005.
FREGNI, F. ; Boggio, PS ; Nitsche, M ; Bermpohl, F ; Feredoes, E ; Marcolin, MA ; Rigonatti, SP ; SILVA, M. T. A. ; Paulus, W ; Pascual-Leone, A . Anodal transcranial direct stimulation of prefrontal cortex enhances working memory. Experimental Brain Research , 2005.
Bermpohl, F ; Pascual-Leone, A ; Amedi, A ; Merabet, LB ; FREGNI, F. ; Gaab N ; Alsop D ; Schlaug G ; Northoff, G . Dissociable networks for the expectancy and perception of emotional stimuli in the human brain. NeuroImage (Orlando) , 2005.
FREGNI, F. ; O'Connor M ; Pascual-Leone, A . ECT and rTMS for depression. British Journal of Psychiatry , 2005.
FREGNI, F. ; Pascual-Leone, A . Transcranial magnetic stimulation for the treatment of depression in neurologic disorders. Curr Psychiatry Rep, p. 381-390, 2005.
Bermpohl, F ; Pascual-Leone, A ; Amedi, A ; Merabet, LB ; FREGNI, F. ; Gaab N ; Alsop D ; Schlaug G ; Northoff, G . Attentional modulation of emotional stimulus processing: An fMRI study using emotional expectancy. Human Brain Mapping , 2005.
FREGNI, F. ; DaSilva D ; Potvin K ; Ramos-Estebanez C ; Cohen D ; Pascual-Leone, A ; Freedman S . Treatment of chronic visceral pain with brain stimulation. Annals of Neurology , v. 58, n.6, p. 971-972, 2005.
FREGNI, F. ; Simon, DK ; Wu, A ; Pascual-Leone, A . Non-invasive brain stimulation for Parkinson's disease: a systematic review and meta-analysis of the literature. Journal of Neurology, Neurosurgery and Psychiatry , v. 76, n.12, p. 1614-1623, 2005.
FREGNI, F. ; Marcolin, MA ; Myczkowski, ML ; AMIAZ, R ; HASEY, G ; Rumi, DO ; Rosa, MA ; Rigonatti, SP ; CAMPRODON, J. ; WALPOTH, M. ; HEASLIP, J. ; GRUNHAUS, L. ; HAUSMANN, A. ; Pascual-Leone, A . Predictors of antidepressant response in clinical trials of transcranial magnetic stimulation. International Journal of Neuropsychopharmacology , v. Nov23, p. in press, 2005.
FREGNI, F. ; Santos, CM ; Myczkowski, ML ; Rigolino, R ; Gallucci, JN ; Brabosa, ER ; Valente, KD ; Pascual-Leone, A ; Marcolin, MA . Repetitive Transcranial Magnetic Stimulation is as effective as Fluoxetine treatment of depression in patients with Parkinson's Disease. Journal of Neurology, Neurosurgery and Psychiatry , v. 8, n.75, p. 1171-1174, 2004.
Martin PI ; Naeser MA ; Theoret H ; Tormos JM ; Nicholas M ; Kurland J ; FREGNI, F. ; Seekins H ; Doron K ; Pascual-Leone, A . Transcranial Magnetic Stimulation as a complementary treatment for aphasia. Semin Speech Lang, v. 2, n.25, p. 181-191, 2004.
FREGNI, F. ; Merabet, L ; Pascual-Leone, A ; Marcolin, MA . Modulation in motor threshold after a severe episode of gastrointestinal distress. The Journal of Electroconvulsive Therapy , v. 20, p. 50-51, 2004.
FREGNI, F. ; Conceicao Souza, GE ; Tarico, MA ; Mutarelli, EG . Phrenic paresis and respiratory insufficiency associated with cervical spondylotic myelopathy. Acta Neurochirurgica , v. 146, p. 309-312, 2004.
FREGNI, F. ; Souza, ST ; Bermpohl, F ; Marcolin, MA ; Herzog A ; Pascual-Leone, A ; Valente, KD . Antiepileptic effects of repetitive TMS in patients with cortical malformations: an EEG and clinical study. Stereotact Func Neurosurgery, 2004.
Naeser MA ; Martin PI ; Nicholas M ; Baker E ; Seekins H ; Kobayashi M ; Theoret H ; FREGNI, F. ; Tormos JM ; Pascual-Leone, A . TMS to Right Broca?s area: improvement in picture naming in chronic aphasia. Brain Lang, 2004.
Naeser MA ; Martin PI ; Nicholas M ; Baker E ; Seekins H ; Helm-Estabrooks N ; Cayer-Meade C ; Kobayashi M ; FREGNI, F. ; Pascual-Leone, A . Improved Naming after TMS Treatments in a Chonic, Global Aphasia Patient- Case Report. Neurocase, 2004.
Naeser MA ; Martin PI ; FREGNI, F. ; Nicholas M ; Kurland J ; Doron K ; Baker E ; Theoret H ; Tormos JM ; Pascual-Leone, A . Improving Picture Naming in Aphasia using TMS. Behavioral Neurology, 2004.
FREGNI, F. . O retorno da estimulação cerebral na terapêutica dos transtornos neuropsiquiátricos: o papel da estimulação magnética transcraniana na prática clínica. Revista de Psiquiatria Clinica, 2004.
FREGNI, F. ; CONFORTO, A. B. ; Martin, MG ; Leite, CC ; Yamamoto, FI ; Scaff, M . Magnetic resonance imaging of Wallerian degeneration in stroke. Arch Neurol, v. 10, n.60, p. 1466-1467, 2003.
FREGNI, F. . Bilateral hemifacial spasm: case report. Arq Neuropsiquiatr, v. 1, n.61, p. 115-118, 2003.
FREGNI, F. . Treatment of subclavian steal syndrome with percutaneous transluminal angioplasty and stenting: case report. Arq Neuropsiquiatr, v. 1, n.61, p. 95-99, 2003.
FREGNI, F. . Pure alexia and hemianopia related to dissection of the internal carotid artery. Cerebrovasc Dis, v. 1-2, n.15, p. 151-152, 2003.
FREGNI, F. ; Pascual-Leone, A . Repetitive transcranial magnetic stimulation to treat Parkinson Disease. Journal Watch Neurology, v. 10, n.5, p. 73-74, 2003.
FREGNI, F. . Espasmo hemifacial bilateral: relato de caso e revisão de literatura. Arq. Neuropsiq, p. 115-118, 2003.
FREGNI, F. ; Pascual-Leone, A . Estimulação Magnética Transcraniana: Uma Nova Ferramenta para o Tratamento da Depressão?. Revista de Psiquiatria Clínica, v. ., p. 253-265, 2001.
FREGNI, F. ; Boggio, PS (Org.) ; Brunoni, AR (Org.) . Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. 1. ed. Sarvier, 2011. v. 1. 570p .
Brunoni, AR ; Boggio, PS ; FREGNI, F. . Estimulação Elétrica no Sistema Nervoso Central: Uma Breve Revisão Histórica. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. 1, p. 3-20.
Oliveira MB ; FREGNI, F. . Estimulação Transcraniana por Corrente Alternada. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. , p. 76-82.
Fiorelli P ; FREGNI, F. . Doença de Parkinson. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. , p. 117-132.
Muzy G ; FREGNI, F. . Distonia. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. , p. 149-161.
Borges IC ; Andrade DC ; FREGNI, F. . Dor Aguda. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. , p. 177-198.
Mendonça ME ; FREGNI, F. . Dor Crônica. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. , p. 199-217.
Coelho G ; Vieira GP ; FREGNI, F. . Aplicações da Neuromodulação em Neurocirurgia. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. , p. 504-517.
Brunoni, AR ; FREGNI, F. . Pesquisa Clínica. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. , p. 518-536.
Brunoni, AR ; Boggio, PS ; FREGNI, F. . Perspectivas e Desafios. In: Fregni F, Boggio PS, Brunoni, AR. (Org.). Neuromodulação Terapêutica - Princípios e Avanços da Estimulação Cerebral Não Invasiva em Neurologia, Reabilitação, Psiquiatria e Neuropsicologia.. .ed.São Paulo: Sarvier, 2011, v. , p. 537-546.
Marcolin, MA ; Rigonatti, SP ; Rumi, DO ; SARTORELLI, M. C. B. ; Mansur, CGS ; FREGNI, F. ; Boggio, PS ; CABRAL, S. B. ; Rosa, MA ; Gattaz, WF . Estimulação Magnética Transcraniana. In: Eduardo Pondé de Sena. (Org.). Manual de Psicofarmacologia Clinica. 2ed.Rio de Janeiro: Editora Guanabara Koogan, 2006, v. 1, p. 311-324.
Boggio, PS ; FREGNI, F. ; Rigonatti, SP ; Marcolin, MA ; SILVA, M. T. A. . Estimulação Magnética Transcraniana e neuropsicologia: novas abordagens em reabilitação. In: Elizeu Coutinho de Macedo; Fernando Cesar Capovilla. (Org.). Temas em neuropsicolinguistica. 1ed.Sao Paulo: Tecmedd, 2005, v. 1, p. 237-246.
Boggio, PS ; Ferreira, MJ ; Mansur, CGS ; Lima, MC ; Marcolin, MA ; Rigonatti, SP ; FREGNI, F. . Estimulação transcraniana por corrente contínua em pacientes que sofreram acidente vascular cerebral. In: Elizeu Coutinho de Macedo; Fernando César Capovilla. (Org.). Temas em neuropsicolinguistica. 1ed.São Paulo: Tecmedd, 2005, v. 1, p. 247-254.
Marcolin, MA ; Rigonatti, SP ; FREGNI, F. ; Rumi, DO ; Mansur, CGS ; Santos, CM ; Gallucci, JN ; Rosa, MO ; Rosa, MA ; Myczkowski, ML ; Boggio, PS . Estimulação Magnética Transcraniana: o futuro dos tratamentos biológicos?. In: Sergio Paulo Rigonatti; Moacyr Alexandro Rosa; Marina Odebrecht. (Org.). Eletroconvulsoterapia. 1ed.Sao Paulo: Vetor Editora Psico-Pedagógica Ltda, 2004, v. 1, p. 119-140.
FREGNI, F. ; Pascual-Leone, A ; Bermpohl, F ; Maia, F ; Marcolin, MA ; Boggio, PS ; Rigonatti, SP . TMS over right DLPFC improves affective setshifting in patients with Major Depressive Disorder. In: XXI Congresso Brasileiro de Neurologia, 2004, Brasília - DF. Arquivos de Neuro-Psiquiatria, 2004. v. 66. p. 6-6.
FREGNI, F. ; Santos, CM ; Rigolino, R ; Myczkowski, ML ; Valente, KD ; Boggio, PS ; Rigonatti, SP ; Pascual-Leone, A ; Marcolin, MA ; Brabosa, ER . Repetitive Transcranial Magnetic Stimulation is as effective as Fluoxetine in the treatment of Depression in Parkinson Disease patients. In: XXI Congresso Brasileiro de Neurologia, 2004, Brasilia - DF. Arquivos de Neuro-Psiquiatria, 2004. v. 66. p. 25-25.
FREGNI, F. ; Coracini, K ; Souza, ST ; Bermpohl, F ; Boggio, PS ; Merabet, L ; Rigonatti, SP ; Marcolin, MA ; Pascual-Leone, A ; Valente, KD . Low frequency Transcranial Magnetic Stimulation decreased cortical excitability of patients with cerebral cortical malformations: A TMS and EEG study. In: XXI Congresso Brasileiro de Neurologia, 2004, Brasilia - DF. Arquivos de Neuro-Psiquiatria, 2004. v. 66. p. 27-27.
FREGNI, F. ; Maia, F ; Boggio, PS ; Bermpohl, F ; Rigonatti, SP ; Pascual-Leone, A ; Marcolin, MA ; Brabosa, ER . Acute placebo effect in Parkinson Disease Patients. In: XXI Congresso Brasileiro de Neurologia, 2004, Brasilia - DF. Arquivos de Neuro-Psiquiatria, 2004. v. 66. p. 146.
FREGNI, F. ; DaSilva D ; Ramos-Estebanez C ; Cohen D ; Potvin K ; Pascual-Leone, A ; Freedman S . A nove approach to treatment of pain in chronic pancreatitis: a double blind, sham controlled pilot trial of repetitive transcranial magnetic stimulation. In: Annual Meeting of American Pancreatic Association Meeting, 2004, Chicago. Annual Meeting of American Pancreatic Association Meeting, 2004.
FREGNI, F. ; Monte-Silva KK ; Oliveira MB ; Herzog A ; Pascual-Leone, A ; Guedes RC . The effects of repetitive electrical stimulation on cortical spreading depression: potential implications for the treatment of depression. In: 2004 Biennial Meeting, Neuromodulation ? defining the future, 2004, Cleveland. Annals of 2004 Biennial Meeting, Neuromodulation ? defining the future, 2004.
FREGNI, F. ; Santos, CM ; Marcolin, MA ; Pascual-Leone, A ; Silveira-Moriyama L ; Brabosa, ER . Repetitive TMS is as effective as fluoxetine in the treatment of depression in PD patients. In: 8th International Congress of Parkinson?s Disease and Movement Disorders, 2004, Rome. Movement Disorders, 2004. p. 239-240.
FREGNI, F. ; Boggio, PS ; Silva MTA ; Marcolin, MA ; Pascual-Leone, A ; Brabosa, ER . Rapid-rate repetitive transcranial magnetic stimulation and cognitive function in Parkinson?s disease patients: A safety study.. In: 8th International Congress of Parkinson?s Disease and Movement Disorders, 2004, Rome. Movement Disorders, 2004. p. 240-241.
FREGNI, F. ; Maia, F ; Boggio, PS ; Bermpohl, F ; Pascual-Leone, A ; Brabosa, ER . The Placebo effect in Parkinson?s disease patients: is this an acute effect?. In: 8th International Congress of Parkinson?s Disease and Movement Disorders, 2004, Rome. Movement Disorders, 2004. p. S228.
Dias AE ; FREGNI, F. ; Rigonatti, SP ; Pascual-Leone, A ; Marcolin, MA ; Brabosa, ER . Repetitive transcranial magnetic stimulation: May it be a potential treatment for speech dysfunction in Parkinson?s disease patients?. In: 8th International Congress of Parkinson?s Disease and Movement Disorders, 2004, Rome. Movement Disorders. p. S241-S242.
Ramos-Estebanez C ; Machii K ; Merabet C ; Romei V ; FREGNI, F. ; Rizzo JF ; Pascual-Leone, A . Tactile modulation of occipital cortex function: a TMS study. In: 5th International Multisensory Research Forum, 2004, Barcelona. Annals of 5th International Multisensory Research Forum, 2004.
FREGNI, F. . Repetitive Transcranial Magnetic Stimulation: A Randomizaed single blind Comparison of Efficacy with Electroconvulsive Therapy for Severe Resistant Nonpsychotic Unipolar Depression. In: 14th Annual Meeting of the ACT, 2004, New York. Anais do 14th Annual Meeting of the ACT.
FREGNI, F. . Transcranial Magnetic Stimulation Accelerates the Antidepressant Effect of Amytriptiline in Severe Depression. In: 14th Annual Meeting of the ACT, 2004, New York. Anais do 14th Annual Meeting of the ACT, 2004.
FREGNI, F. . Neural correlates of emotional expectancy. In: Human Brain Mapping, 2004, Budapeste. Anais do Human Brain Mapping, 2004.
FREGNI, F. . Acute Placebo Effect in Parkinson Disease Patients. In: International Neuroscience Conference, 2004, Natal. Anais do International Neuroscience Conference, 2004.
FREGNI, F. . Low frequency transcranial magnetic stimulation decreased cortical excitability of patients with cerebral cortical malformations: a TMS and EEG study. In: International Neuroscience Conference, 2004, Natal. Anais do International Neuroscience Conference, 2004.
FREGNI, F. . Repetitive TMS is as effective as fluoxetine in the treatment of depression in PD patients. In: 14th Annual Meeting of the ACT, 2004, Nova York. Anais do 14th Annual Meeting of the ACT, 2004.
FREGNI, F. . An uncommon presentation of low-back pain: intramedullary abscess of the spinal cord. In: 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, 2003, Praga. Proceedings of 2nd World Congress of the International Society of Physical and Rehabilitation Medicine, 2003.
FREGNI, F. . Increase of potency of antidepressant drugs with rTMS. In: American Psychiatric Association Meeting, 2003, São Francisco. Anais do American Psychiatric Association Meeting, 2003.
FREGNI, F. . Difficulties of finding motor threshold in patients with parkinson disease with severe rest tremor. In: International meeting - transcranial magnetic stimulation in movement disorders, 2003, Genova. Anais do International meeting - transcranial magnetic stimulation in movement disorders, 2003.
FREGNI, F. . Comparison of Speech Analysis in depressed patients with Parkinson?s disease treated with rapid-rate transcranial magnetic stimulation or fluoxetine. In: International meeting - Transcranial magnetic stimulation in movement disorders, 2003, Genova. Anais do International meeting - Transcranial magnetic stimulation in movement disorders, 2003.
FREGNI, F. . Comparison of Speech Analysis in depressed patients with Parkinson?s disease treated with rapid-rate transcranial magnetic stimulation or fluoxetine. In: International meeting - Transcranial magnetic stimulation in movement disorders, 2003, Genova. Anais do International meeting - Transcranial magnetic stimulation in movement disorders, 2003.
FREGNI, F. . Comparison of Speech Analysis in depressed patients with Parkinson?s disease treated with rapid-rate transcranial magnetic stimulation or fluoxetine. In: International meeting - Transcranial magnetic stimulation in movement disorders, 2003, Genova. Anais do International meeting - Transcranial magnetic stimulation in movement disorders, 2003.
FREGNI, F. . Comparison of cognitive effects of the rapid-rate transcranial magnetic stimulation or fluoxetine in depressed patients with Parkinson?s disease. In: International meeting - Transcranial magnetic stimulation in movement disorders, 2003, Genova. Anais do International meeting - Transcranial magnetic stimulation in movement disorders, 2003.
FREGNI, F. . Brain spect in a depressed patient with Parkinson desease treated with rapid-rate transcranial magnetic stimulation: a case report. In: International meeting - Transcranial magnetic stimulation in movement disorders, 2003, Genova. Anais do International meeting - Transcranial magnetic stimulation in movement disorders, 2003.
FREGNI, F. . Comparison of rapid-rate transcranial magnetic stimulation and fluoxetine in depressed patients with Parkinson?s disease: a randomized trial. In: International meeting - Transcranial magnetic stimulation in movement disorders, 2003, Genova. Anais do International meeting - Transcranial magnetic stimulation in movement disorders, 2003.
FREGNI, F. . Change in motor threshold with hypokalemia in a parkinson disease patient: a randomized trial. In: International meeting - Transcranial magnetic stimulation in movement disorders, 2003, Genova. Anais do International meeting - Transcranial magnetic stimulation in movement disorders, 2003.
FREGNI, F. . A report of six patients with choking phobia and panic disorder. In: XVII Congresso Brasileiro de Psiquiatria, 1999. Resumos do XVII Congresso Brasileiro de Psiquiatria, 2003.
Rosa, MA ; Rosa, MO ; Rigonatti, SP ; Marcolin, MA ; Verderosi, SF ; Cillo, MT ; Daltio, CS ; Abreu, LN ; Belegarde, IM ; FREGNI, F. . Etomidate, Propofol and Thiopental for Electroconvulsive Therapy (ECT) in Depression: Differences in Cardio-Vascular Effects, Time for Recovery, Clinical Response and ECT Parameters. Journal of ECT , v. 22, p. 78-78, 2006.
DaSilva, Alexandre F. ; Mendonca, Mariana E. ; Zaghi, Soroush ; Lopes, Mariana ; DosSantos, Marcos Fabio ; Spierings, Egilius L. ; Bajwa, Zahid ; Datta, Abhishek ; Bikson, Marom ; Fregni, Felipe . tDCS-Induced Analgesia and Electrical Fields in Pain-Related Neural Networks in Chronic Migraine. Headache , 2012.
de Souza Custódio, Juliana Cardoso ; Martins, Cleciane Waldetário ; Lugon, Marcelo Di Marcello Valladão ; Fregni, Felipe ; Nakamura-Palacios, Ester Miyuki . Epidural direct current stimulation over the left medial prefrontal cortex facilitates spatial working memory performance in rats. Brain Stimulation: basic, translational and clinical research in neuromodulation , 2012.
FREGNI, F. . 'Estimulação magnética transcraniana em síndromes dolorosas: revisão dos estados atuais'. 2012. (Apresentação de Trabalho/Simpósio).
Fregni, Felipe . Como se forma a falsa memória na alienação parental e suas consequências.. 2011. (Apresentação de Trabalho/Conferência ou palestra).
FREGNI, F. ; Maia, F ; Boggio, PS ; Bermpohl, F ; Rigonatti, SP ; Pascual-Leone, A ; Marcolin, MA ; Brabosa, ER . Acute placebo effect in Parkinson Disease patients. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. ; Pascual-Leone, A . Melhora da nomeação após tratamento com Estimulação Magnética Repetitiva com Afasia Crônica. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. ; Coracini, K ; Souza, ST ; Bermpohl, F ; Boggio, PS ; Merabet, L ; Rigonatti, SP ; Marcolin, MA ; Pascual-Leone, A ; Valente, KD . Low frequency Transcranial Magnetic Stimulation decreased cortical excitability of patients with cerebral cortical malformations: A TMS and EEG study. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. ; Santos, CM ; Rigolino, R ; Myczkowski, ML ; Valente, KD ; Boggio, PS ; Rigonatti, SP ; Pascual-Leone, A ; Marcolin, MA ; Brabosa, ER . Repetitive Transcranial Magnetic Stimulation is as effective as Fluoxetine in the treatment of depression in Parkinson Disease. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. ; Maia, F ; Bermpohl, F ; Boggio, PS ; Rigonatti, SP ; Pascual-Leone, A ; Marcolin, MA . TMS over right DLPFC improves affective setshifting in patients with Major Depressive Disorder. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. ; Maia, F ; Bermpohl, F ; Boggio, PS ; Rigonatti, SP ; Pascual-Leone, A ; Marcolin, MA . Estimulação Magnética Transcraniana do Córtex Pré-Frontal Dorsolateral Direito melhora a performance na tarefa de julgamento afetivo em pacientes com Depressão Maior. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. ; Bermpohl, F ; Boggio, PS ; Rigonatti, SP ; Santos, CM ; Gallucci, JN ; Mansur, CGS ; Rosa, MA ; Rumi, DO ; Odebrecht, M . Estimulação Magnética Transcraniana do Córtex Pré-Frontal Dorsolateral Direito melhora a performance na tarefa de julgamento afetivo em pacientes com Depressão Maior. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. ; Maia, F ; Boggio, PS ; Bermpohl, F ; Rigonatti, SP ; Santos, CM ; Gallucci, JN ; Mansur, CGS ; Rosa, MA ; Rumi, DO . O efeito placebo agudo em pacientes com Doença de Parkinson. 2004. (Apresentação de Trabalho/Congresso).
Rumi, DO ; Gattaz, WF ; Rigonatti, SP ; Rosa, MA ; Rosa, MO ; FREGNI, F. ; Myczkowski, ML ; Marcolin, MA . Aceleração e potencialização da resposta antidepressiva com Estimulação Magnética Transcraniana de repetição (EMTr). 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. . Sensitivity and Specificity of Magnetic Resonance Angiography in Ischemic Stroke in the Young. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. . Improved Naming after rTMS Treatment in Chronic Aphasia Patients. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. . Sustained Improved Naming after rTMS Treatment in a Severe Aphasia Patient. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. . Improvement in Mood Scale for Chronic Aphasia Patients treated with rTMS. 2004. (Apresentação de Trabalho/Congresso).
FREGNI, F. ; Vargas C . Estimulação Magnética Transcraniana I (Medição da plasticidade cortical através do pulso simples e do pulso pareado).. 2011. (Curso de curta duração ministrado/Outra).
FREGNI, F. ; Brunoni, AR . Metodologia de pesquisa Clínica aplicada à Neuromodulação.. 2011. (Curso de curta duração ministrado/Outra).
FREGNI, F. ; Lima, MC . Estimulação Magnética Transcraniana II (Aplicações Clínicas - EMT repetitiva).. 2011. (Curso de curta duração ministrado/Outra).
FREGNI, F. ; Boggio, PS . II Curso Teórico-Prático de Estimulação Cerebral Não-Invasiva. 2011. (Curso de curta duração ministrado/Outra).
FREGNI, F. . I Curso de Educação Continuada em Neuromodulação. 2010. (Curso de curta duração ministrado/Outra).
FREGNI, F. . Métodos de estimulacão cerebral na prática clínica e no estudo do cérebro. 2007. .

Projetos de pesquisa

2022 - Atual

Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain with Machine Learning to Predict Treatment Response, Descrição: A dor do membro fantasma é considerada um distúrbio extremamente difícil de tratar, uma vez que os tratamentos tradicionais não são eficazes no direcionamento dos circuitos neuronais desadaptativos associados à dor crônica. A estimulação transcraniana por corrente contínua (ETCC) é uma técnica de estimulação cerebral não invasiva e segura que demonstrou reverter a plasticidade mal adaptativa, bem como reduzir a dor na dor neuropática e outras síndromes dolorosas. Nossos objetivos específicos deste projeto testarão as seguintes hipóteses: (Objetivo 1) ETCC combinada com terapia somatossensorial associada a um tamanho de efeito significativamente maior (de pelo menos 1) em comparação com a condição de controle na redução da dor; (Objetivo 2) identificar preditores de resposta deste tratamento combinado usando algoritmos de aprendizado de máquina ajudará a identificar diferentes fenótipos de dor em pacientes com PLP e melhorar seu tratamento alvo; (Objetivo 3) o tratamento combinado irá reforçar o tônus #8203;#8203;parassimpático (conforme indexado pela maior variabilidade da frequência cardíaca) e reduzir a ativação simpática, alterações que serão correlacionadas com diminuições de PLP. Esta contribuição é significativa porque, embora vários estudos tenham testado a eficácia da ETCC para a dor crónica, há necessidade de avaliar a sua eficácia num cenário do mundo real, e esta proposta fornece dados críticos para desenvolver uma intervenção segura e única a ser aplicada. em casa, o que pode, portanto, aumentar o seu acesso a populações sub-representadas e diminuir os custos terapêuticos. Esta investigação também fornecerá dados mecanísticos sobre preditores de resposta e mudanças no tônus #8203;#8203;parassimpático associado a esta intervenção. A pesquisa proposta é inovadora porque oferece um desenho de ensaio pragmático para o tratamento de PLP e visa validar um dispositivo ETCC domiciliar que seja viável e capaz de fornecer tratamentos mais longos remotamente. Esta proposta também está investigando a VFC como um marcador substituto para reduzir a PLP e avaliando sua viabilidade em um ambiente da vida real. Por fim, esta proposta valida preditores de resposta ao tratamento de PLP utilizando algoritmos de machine learning.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Felipe Fregni - Coordenador.
2022 - Atual

Mechanisms of Open and Hidden Placebo in Stroke Recovery, Descrição: Propomos investigar os mecanismos neurais do placebo (aberto e oculto) em indivíduos com AVC. Esta proposta baseia-se no nosso ensaio clínico recentemente concluído NIH R21 (R21HD079048-01A1), que mostrou que o efeito placebo que contribui para a recuperação motora foi grande e superior à fluoxetina isoladamente. Além disso, encontramos uma assinatura neural diferente do placebo e da EMTr M1 neste ensaio, apoiada por outros ensaios anteriores que conduzimos. Além disso, nosso laboratório esteve envolvido em outros grandes ensaios com efeitos placebo significativos na aprendizagem motora. Esta proposta conduzirá um ensaio experimental no qual 56 indivíduos com AVC crônico serão randomizados em quatro grupos (2:2:2:1): apenas placebo aberto (16 indivíduos), EMTr simulada apenas (placebo oculto) (16 indivíduos), sem tratamento (16 indivíduos) e EMTr M1 isoladamente (8 indivíduos). Os assuntos serão avaliados antes e depois da intervenção usando marcadores neurofisiológicos de conectividade para testar questões mecanicistas específicas com base em nossos dados preliminares. Usaremos análise quantitativa de eletroencefalografia (EEG) de áreas pré-frontais e sensório-motoras e TMS de pulso único e, secundariamente, pareado para avaliar a excitabilidade corticoespinhal e intracortical. Nossa hipótese é que o placebo (aberto e oculto) terá uma assinatura EEG/neural específica caracterizada por um aprimoramento no EEG de assimetria alfa frontal esquerda (FAA) e um aumento da conectividade EEG pré-motora da banda beta. Com base nisso, testaremos dois objetivos: Objetivo 1: Avaliar se um placebo oculto (placebo administrado em um ensaio clínico indexado por EMTr simulada) tem uma assinatura EEG de placebo específica em comparação com nenhum tratamento, e Objetivo 2: Avaliar se também o o placebo aberto (OP) tem uma assinatura EEG específica em comparação com nenhum tratamento (semelhante ao placebo oculto).. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Felipe Fregni - Coordenador.
2021 - Atual

Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome, Descrição: O objetivo deste estudo é avaliar os efeitos da ETCC em combinação com UST para o tratamento da dor em indivíduos com Síndrome do Túnel do Carpo. Os investigadores levantam a hipótese de que haverá uma diminuição nos níveis de dor com estimulação ativa, quando comparada à estimulação simulada.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Felipe Fregni - Coordenador.
2019 - Atual

Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability., Descrição: Este ensaio tem como objetivo compreender o mecanismo e testar se a estimulação transcraniana por corrente contínua (ETCC) combinada com ultrassom transcraniano (TUS) (tDCS + UST) combinada com fisioterapia (PT) irá induzir efeitos terapêuticos significativos na instabilidade postural na doença de Parkinson (PT ) pacientes. Os investigadores desenvolveram um estudo duplo-cego, controlado por placebo e randomizado para investigar os efeitos de 2 semanas de TDCS + UST na instabilidade postural em pacientes com DP recebendo TP. (Seguido de sessões quinzenais por mais 2 semanas na Fase II). , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Felipe Fregni - Coordenador.
2018 - Atual

Optimized tDCS for fibromyalgia: targeting the endogenous pain control system, Descrição: A dor da fibromialgia (FM) afeta mais milhares de pessoas pode ter um impacto considerável na qualidade de vida dos pacientes e nos custos para a sociedade (por exemplo, tratamentos ou custos de desemprego). Dados os efeitos limitados e variáveis #8203;#8203;da maioria das intervenções terapêuticas para a FM, existe uma necessidade clínica não atendida para o desenvolvimento de novas intervenções na FM. Evidências recentes sugerem que a dor causada pela FM pode estar relacionada a déficits no controle regulatório endógeno da dor. Neste contexto, a nossa hipótese central é que, para melhorar a sua eficácia, novos tratamentos da FM precisam ter como alvo redes neurais específicas associadas a este sistema endógeno de regulação da dor. Nossa justificativa é baseada em estudos que mostram que a estimulação transcraniana por corrente contínua (ETCC) do córtex motor primário é uma poderosa técnica de neuromodulação não invasiva conhecida por modular significativamente a plasticidade neural e aliviar a dor crônica.Nossos objetivos específicos são: (i) avaliar os efeitos da ETCC e do exercício aeróbico no controle da dor endógena, avaliado pela soma lenta temporal da dor (TSPS) e pela modulação condicionada da dor (CPM); (ii) determinar o efeito dessas intervenções nos marcadores corticais de controle inibitório que também são afetados na FM, como a inibição intracortical avaliada por estimulação magnética transcraniana (TMS) e alterações na disritmia tálamo-cortical avaliada por EEG; (iii) avaliar se o envolvimento dos dois principais alvos testados neste estudo STS e CPM está associado a mudanças nos resultados da dor (por exemplo, Brief Pain Inventory e outras escalas clínicas). Nossa abordagem principal será realizada por meio de um ensaio clínico randomizado 2x2 mecanístico fatorial controlado em 94 pacientes com diagnóstico de FM. Os assuntos serão randomizados para um dos quatro grupos: tDCS e AE; ETCC simulada e EA; ETCC ativa e NAE (não-EA= intervenção de controle para EA); sham tDCS e NAE. As descobertas deste estudo serão significativas, pois existe uma necessidade clínica não atendida para o desenvolvimento de novas terapias na FM, particularmente as não farmacológicas, baseadas em abordagens mecanicistas e no envolvimento do alvo.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Felipe Fregni - Coordenador.
2018 - Atual

O déficit da inibição como marcador de neuroplasticidade na reabilitação, Descrição: De acordo com a OMS, mais de um bilhão de pessoas no mundo possuem alguma deficiência, o que não é apenas uma questão de saúde pública, mas também de direitos humanos. Em 2015, o Global Burden of Diseases apresentou evidências epidemiológicas mundiais de que 74 do total de anos vividos com incapacidade estão relacionados a condições de saúde que podem ser beneficiadas pela reabilitação. Por essa razão, o desenvolvimento de novas terapias e pesquisas em reabilitação são um dos principais objetivos do Plano de Ação Global da OMS para 2014-2021. No entanto, o pouco conhecimento sobre os mecanismos biológicos envolvidos no processo de reabilitação é uma das principais limitações enfrentadas para a construção de um conhecimento sólido. Há evidencias de que a plasticidade cerebral é o mecanismo central envolvido no processo de recuperação funcional de pacientes com déficit de diferentes etiologias. Embora muito já se tenha avançado no entendimento da plasticidade cerebral, pouco foi incorporado na prática da reabilitação, principalmente pela escassez de desenhos de estudo que privilegiem a translação do conhecimento. Dessa forma, propõe-se um estudo em quatro grupos de sujeitos (com AVC, lesão medular, amputações e osteoartrose) visando a entender os mecanismos de neuroplasticidade envolvidos no processo de reabilitação motora, utilizando para isso as técnicas de EMT, fNIRS e EEG de alta densidade, antes e depois do período de reabilitação. Por meio deste projeto, espera-se obter um melhor entendimento dos mecanismos de neuroplasticidades envolvidos na reabilitação, e o desenvolvimento de biomarcadores neurofisiológicos "transdiagnósticos", os quais terão grande relevância para o aperfeiçoamento científico e terapêutico da reabilitação. (AU). , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Felipe Fregni - Coordenador / Marta Imamura - Integrante / Linamara Rizzo Battistella - Integrante.
2013 - Atual

NEUROMODULAÇÃO TRANSCRANIANA COMO INSTRUMENTO DIAGNÓSTICO E TERAPÊUTICO, Descrição: O uso da estimulação transcraniana no tratamento da dor e transtornos neuropsiquiátricos tem como suporte teórico evidências recentes, que sugerem reduzir a dor e modificar correlatos neurofisiológicos da experiência dolorosa. Em estudos com ratos conduzidos pelo nosso grupo a ETCC reverteu à dor induzida em modelo de artrite e a hiperalgesia induzida pelo estresse crônico. A partir destas evidências adicionadas à eficácia da ETCC na área do córtex motor primário para tratar síndromes dolorosas, o objetivo principal deste projeto temático será investigar o uso das técnicas de neurmodulação transcraniana como instrumento diagnóstico e terapêutico num conjunto de subprojetos. Trata-se de um projeto temático que envolve seis subprojetos relacionados a técnicas neuromodulatórias cujas metas específicas são: i) Avaliar os processos de neuroplasticidade adaptativa cerebral em pacientes com fibromialgia submetidos à aplicação de ETCC, à administração de pregabalina e à combinação de ambas. O impacto do tratamento será avaliado por meio de desfechos relacionados ao limiar de dor, intensidade da dor, catastrofismo relacionado à dor, qualidade de vida, parâmetros de excitabilidade cortical, acoplamento metabólico vascular (relação oxi-deoxihemoglobina no território cortical correspondente ao território de estímulo periférico usando espectroscopia óptica de neuroimgaem funcional) e marcadores séricos ao efeito do tratamento: agudo, intensivo, na manutenção e pós-tratamento. ii) Avaliar a eficácia da ETCC e da IMS comparada à do tratamento simulado (sham), na redução da dor, na capacidade funcional e no sistema neuroimunoendócrino de pacientes com osteoartrite. iii) Investigar o efeito da relação entre o nível de deslocamento da atenção, parâmetros de excitabilidade cortical, limiar de dor, potência dos sistemas moduladores descendentes e marcadores de atividade neurotrófica em pacientes fibromiálgicas, comparando-as a controles saudáveis, bem como o efeito da ETCC nestes desfechos. iv) Investigar a correlação entre o nível de resiliência, catastrofismo e deslocamento da atenção em pacientes com dor crônica por fibromialgia. Assim como investigar a correlação entre resiliência, dor e sistemas moduladores, sobretudo a relação entre resiliência e marcadores de neuroplasticidade. Adicionalmente, comparar o efeito da ETCC nestes desfechos entre pacientes resilientes e não resilientes e destes com sujeitos saudáveis. v) Comparar a eficácia da TMS na redução da dor, regulação do eixo imune-pineal, função autonômica e pensamento catastrófico. vi) Desenvolver um aparelho de ETTC de baixo custo para uso domiciliar, validá-lo em sujeitos saudáveis e num segundo momento utilizar o aparelho no tratamento de patologias especificas a citar: fibromialgia, transtorno de déficit de atenção e depressão maior. Palavras chaves: pain; depression; TDCs; TMS; neuroplasticity; BDNF; QST.. , Situação: Desativado; Natureza: Pesquisa. , Integrantes: Felipe Fregni - Integrante / Caumo, Wolnei - Coordenador / TORRES, IRACI L.S. - Integrante / BRUNONI, A.R. - Integrante / Paulo Sanches - Integrante.

Prêmios

2012

Honoris Causa, Facultad de Medicina Humana - Universidad de San Martín de Porres.

Histórico profissional

Endereço profissional

Beth Israel Deaconess Medical Center / Harvard Medical School, Center for Noninvasive Brain Stimulation. , 330 Brookline Ave - KS430, 02215 - Boston, - Estados Unidos, Telefone: (617) 6675272, Fax: (617) 9755322

Experiência profissional

2013 - Atual

Universidade Federal do Rio Grande do Sul

Vínculo: , Enquadramento Funcional:

2008 - Atual

Universidade de São Paulo

Vínculo: Professor de Pós-Graduação NEC, Enquadramento Funcional: Orientador - po-graduacao, Carga horária: 6

2008 - Atual

Spaulding Rehabilitation Hospital

Vínculo: Diretor, Enquadramento Funcional: Diretor do Laboratório de Neuromodulação, Carga horária: 40

2007 - Atual

Harvard Medical School

Vínculo: , Enquadramento Funcional: Professor Associado da Harvard Medical School, Carga horária: 40

Atividades

08/2006
Ensino, Clinical Research, Nível: Pós-Graduação,Disciplinas ministradas, Clinical Research
05/2005
Pesquisa e desenvolvimento, Center for Noninvasive Brain Stimulation.,Linhas de pesquisa

2007 - Atual

Harvard School Of Public Health

Vínculo: Colaborador, Enquadramento Funcional: Instrutor, Carga horária: 4

Atividades

08/2006
Ensino, Field Trip, Nível: Pós-Graduação,Disciplinas ministradas, Health care system/infectious diseases/developing countries