Dennis Ricardo August Mans
Possui graduação em Biologia Médica pela Universiteit Utrecht(1984), doutorado em Biologia Tumoral pela University of Amsterdam(1991) e pós-doutorado pela National Cancer Institute(1992). Atualmente é Contrato da Hospital de Clínicas de Porto Alegre, funcionário da Universidade Federal do Rio Grande do Sul e Pesquisador da Universidade Luterana do Brasil. Tem experiência na área de Medicina.
Informações coletadas do Lattes em 22/11/2022
Acadêmico
Formação acadêmica
Doutorado em Biologia Tumoral
1988 - 1991
University of Amsterdam
Título: Mechanism of Action of Etoposide: a Study at the Cellular and Molecular Level,
Pós-doutorado
1991 - 1992
Pós-Doutorado. , National Cancer Institute, NCI, Estados Unidos. , Grande área: Ciências Biológicas / Área: Farmacologia / Subárea: Farmacologia Bioquímica e Molecular.
Idiomas
Inglês
Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.
Português
Compreende Razoavelmente, Fala Pouco, Lê Bem, Escreve Pouco.
Holandês
Compreende Bem, Fala Bem, Lê Bem, Escreve Bem.
Áreas de atuação
Grande área: Ciências da Saúde / Área: Medicina.
Grande área: Ciências Biológicas / Área: Bioquímica / Subárea: Biologia Molecular.
Produções bibliográficas
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MANS, D. R. A. ; ROCHA, A. B. ; LENZ, G. ; ANDRÉIA K. FERNANDES, ; LIMA, C. ; MONTEIRO, V. F. ; GONÇALVES, D. ; MOREIRA, J. C. F. ; BRUNETTO, A. L. ; RODNIGHT, R. . Protein Kinase C-Mediated In vitro Invasion of Human Glioma Cells Through Extracellular-Signal-Regulated Kinase and Ornithine Decarboxylase, 2000.
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MANS, D. R. A. ; GRIVICICH, I. M. D. ; SCHWARTSMANN, G. P. G. . Sequence-dependent cell growth inhibition and DNA damage by the irinitecan-5-fluorouracil combination in human colon carcinoma cell lines. submitted, 1999.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; CAMPOS JR, O. C. A. L. L. ; SCHUNEMANN, H. C. A. ; SANDER, E. F. F. A. ; DRA, M. . A phase I and pharmacokinetic study of three-times daily oral etoposide in patients with refractory solid tumors.. Submitted, 1999.
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MANS, D. R. A. ; DRA, M. ; ROCHA ; B, A. . Novel targets for cancer therapy. South -Am. J. Cancer, v. 1, p. 53-69, 1997.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; XAVIER, N. M. D. M. C. ; CALEFFI, M. ; SCHUNEMANN, H. F. F. A. ; KALAKUN, L. ; KOYA, R. ; POHLMANN, P. ; LF, V. . A phase II study of doxorubicin/paclitaxel plus G-CSF for metastatic breast cancer. Oncology, v. 11, n.3, p. 24-29, 1997.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SPRINZ, E. ; KRONFELD, M. ; KALAKUN, L. ; SANDER, E. ; PROLLA, G. ; LEONE, L. ; DRA, G. L. M. . Clinical and Pharmacokinetic study of oral etoposide in patients with AIDS-related Kaposis sarcoma with no prior exposure to cytotoxic therapy.. J. Clin Oncol., v. 15, p. 2118-2124, 1997.
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MANS, D. R. A. ; GRIVICICH, I. M. D. ; MALCON, C. ; BECKER, D. E. M. C. C. ; SCHWARTSMANN, G. . Enhanced etoposide-induced hepato- and hematological toxicity in Wistar rats upon coadministration of the P-glycoprotein-modulating agents tamoxifen and cyclosporin A.. South-Am. J. Cancer, v. 2, p. 114-122, 1997.
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MANS, D. R. A. ; DRA, R. A. M. . Protein Kinase C overexpression in malignant gliomas: an opportunity for therapeutic intervention?. South-Am. J. Cancer, v. 4, p. 261-271, 1997.
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MANS, D. R. A. ; DRA, M. . Highlights of the 88th Annual Meeting of the American Association for Cancer Research (AACR). South-Am. J.Cancer, v. 4, p. 281-288, 1997.
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MANS, D. R. A. ; RUSCHEL, C. R. A. M. D. B. E. ; LEYVA, A. L. A. W. L. ; SCHWARTSMANN, G. . Tamoxifen inhibits particulate-associated protein kinase C activity, and sensitizes cultured human glioblastoma cells not to etoposide but to y-radiation and BCNU. Accepted for publication in Eur J Cancer, 1997.
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MANS, D. R. A. ; AB, M. D. R. . Destaques da reunião anual de 1996 da American Association for Cancer Research (AACR). Vitro Cancerologia, v. 2, p. 59-62, 1996.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SPRINZ, E. ; KALAKUN, L. ; YAMAGUSHI, N. ; SANDER, E. ; GRIVICICH, I. ; KOYA, R. ; DRA, M. . Phase II study of pentosan polysulfate (PPS) in patients with AIDS-related Kaposis sarcoma.. Tumori, v. 82, p. 360-363, 1996.
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MANS, D. R. A. ; DRA, M. ; A, S. ; D, B. ; OLIVEIRA JR, ; CM, P. ; C, B. ; AF, F. F. ; VL, M. ; JL, R. ; FA, J. ; A, L. ; G, S. . Two new cases of hyperpyrimidinuria associated with excessive 5-fluouroracil toxicity.. Ann. Oncol., v. 5, p. 772-773, 1994.
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MANS, D. R. A. ; SCHWARTSMANN, G. M. D. J. F. . Anticancer Drug Discovery and Development. Ciência e Cultura, v. 46, p. 70-81, 1994.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SANDER, E. ; PROLLA, G. ; SPRINZ, E. ; ZAMPEZE, M. ; VINHOLES, J. ; KRONFELD, M. J. F. ; KALAKUN, L. ; DRA, M. . Phase II trial of Pentosan polysulphate (PPS) in patients (pts) with AIDS-related Kaposis sarcoma (KS). AIDS Weekly, 1993.
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MANS, D. R. A. ; WESTMIJZE, J. D. M. L. M. ; BETS, D. H. I. ; LANKELMA, J. S. G. ; RETÈL, J. . Reactions of glutathione with the catechol, the ortho-quinone, and the semi-quinone free radical of etoposide: consequences for DNA inactivation.. Biochem.Pharmacol., v. 43, p. 1761-1768, 1992.
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MANS, D. R. A. ; MANS, D. ; GJ, S. ; M, T. ; MVM, L. ; HM, L. J. J. P. . Modulation by D,L-buthionine-S,R-sulphoximine of etoposide cytotoxicity in human non-small cell lung, ovarian, and breast carcinoma cell lines.. Eur. J. Cancer, v. 28a, p. 1447-1452, 1992.
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MANS, D. R. A. ; GAAST, A. V. D. ; SONNEVELD, P. ; TA, D. M. S. . Intrathecal administration of etoposide in the treatment of malignant meningitis: feasibility and pharmacokinetic data.. Cancer Chemother. Pharmacol., v. 29, p. 335-337, 1992.
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MANS, D. R. A. ; WESTMIJZE, J. M. D. L. M. ; LANKELMA, J. V. M. J. V. S. M. . Formation of different reaction products with single and double-stranded DNA.. Biochem. Pharmacol., v. 42, p. 2131-2139, 1991.
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MANS, D. R. A. ; RETÈL, J. M. D. ; LANKELMA, J. V. M. J. L. M. V. S. M. P. H. . Role of the semi-quinone free radical of the antitumor agent etoposide (VP-16-213) in the inactivation of single-stranded and double-stranded X174 DNA.. Br. J. Cancer, v. 62, p. 54-60, 1990.
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MANS, D. R. A. ; VRIES, J. V. M. J. M. D. L. M. V. S. M. ; RETÈL, J. V. N. ; LANKELMA, J. . Effects of oxygen radical scavengers on the inactivation of ss X174 DNA by the semi-quinone free radical of the antitumor agent etoposide.. Free Rad Res Comm, v. 2, p. 69-86, 1990.
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MANS, D. R. A. ; SLAGER, H. W. R. V. R. ; LOVEREN, H. M. D. V. ; WILBRINK, B. ; OTTER, W. H. D. D. . Initial immunochemical characterization of specific macrophage-arming factor.. Cancer Immunol. Immunother., v. 30, p. 21-27, 1989.
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MANS, D. R. A. ; BARTSCH, H. N. H. ; BARTSCH, C. ; DRA, M. . Partial purification of (a) low molecular weight ovine pineal compound(s) with an inhibiting effect on the growth of human melanoma cells in vitro.. J.Neural Transm., v. 73, p. 135-155, 1988.
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MANS, D. R. A. ; AKKER, E. V. M. J. L. M. M. D. V. D. ; RUITER, C. ; PAPPIE, D. K. P. ; VRIES, J. ; RETÈL, J. ; HM, P. . Effects of the ortho-quinone and the catechol of the antitumor drug VP16-213 on the biological activity of single-stranded X174 DNA.. Biochem. Pharmacol., v. 37, p. 3579-3589, 1988.
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MANS, D. R. A. ; WILBRINK, B. V. R. ; OSKAM, R. M. R. M. D. ; OTTER, W. D. . Immune reactivity in SL2 lymphoma-bearing mice compared with SL2-immunized mice. Cancer Immunol. Immunother., v. 24, p. 25-36, 1987.
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MANS, D. R. A. ; VRIES, J. V. M. J. ; PAPPIE, D. ; RETÉL, J. M. D. V. D. A. L. M. ; GREEF, J. V. D. ; HM, P. . Cytochrome P-450-mediated O-demethylation: a route in the metabolic activation of etoposide(VP-16-213). Cancer Research, v. 47, p. 4658-4662, 1987.
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MANS, D. R. A. ; WEGER, B. R. ; MANS, R. W. R. M. D. ; OSKAM, W. ; OTTER, D. . Immune reactivity in SL2 lymphoma-bearing mice compared with SL2-immunized mice.. . Cancer Immunol Immunother, v. 24, p. 25-36, 1987.
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MANS, D. R. A. ; MAANEN, J. V. ; VRIES, J. ; PAPPIE, D. ; MANS, D. ; AKKER, V. D. ; LAFLEUR, M. ; RETÈL, J. ; GREEF, J. V. D. ; PINEDO, H. . . Cytochrome P-450-mediated O-demethylation: a route in the metabolic activation of etoposide (VP-16-213).. Cancer Res, v. 47, p. 4658-4662, 1987.
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MANS, D. R. A. ; BENTHEM, J. V. ; EBELS, I. M. D. ; MGM, B. . Rhythmic synthesis of various 5-methoxyindoles in the pineal gland of the male adult golden hamsters, kept under the same artificial conditions throughout the year.. J Neural Transm., v. 61, p. 219-237, 1985.
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MANS, D. R. A. ; BENTHEM, J. V. ; EBELS, I. ; MOREÉ, A. B. M. ; DRA, M. . The effect of reduced neopterin on the synthesis of several methylated indoles in the pineal gland of adult male golden hamsters, keept under standardized conditions. J. Neural Transm., v. 62, p. 137-154, 1985.
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MANS, D. R. A. ; BENTHEM, J. V. ; HALDAR-MISRA, C. M. D. ; EBELS, I. ; MGM, B. . Daily and seasonal rythmicity in the methylation of pineal indolic compounds in adult golden male hamsters, kept under natural conditions. J Neural Transm., v. 64, p. 295-321, 1985.
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MANS, D. R. A. ; VAN, J. ; MANS, I. B. D. ; BALEMANS, E. M. . Rhythmic synthesis of various 5-methoxyindoles in the pineal gland of the male adult golden hamsters, kept under the same artificial conditions throughout the year.. . J Neural Transm, v. 61, p. 219-237, 1985.
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MANS, D. R. A. ; VAN, J. ; BENTHEM, I. ; BALEMANS, A. E. M. ; MANS, M. D. . . The effect of reduced neopterin on the synthesis of several methylated indoles in the pineal gland of adult male golden hamsters, kept under standardized conditions. J Neural Transm, v. 61, p. 137-154, 1985.
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MANS, D. R. A. ; VAN, J. ; MANS, C. B. D. ; HALDAR-MISRA, I. ; BALEMANS, E. M. . . Daily and seasonal rhythmicity in the methylation of pineal indolic compounds in adult male golden hamsters, kept under natural conditions. J Neural Transm, v. 64, p. 295-321, 1985.
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MANS, D. R. A. ; MANS, I. M. B. D. ; SMITH, J. ; BENTHEM, V. . . The influence of GABA on the synthesis of N-acetylserotonin, melatonin, O-acetyl-5-hydroxytryptophol, and O-acetyl-5-methoxytryptophol in the pineal gland of the male Wistar rat.. . Reprod Nutr Develop, v. 23, p. 151-160, 1983.
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MANS, D. R. A. ; AB, R. ; G, S. ; G, L. ; R, R. . Signaling to Invasion in Human Glioma Cell Lines Via Protein Kinase C (PKC), Extracellular-Signal-Regulated Kinase (ERK), and Ornithine Decarboxylase (ODC. In: 91st AACR Annual Meeting, 2000, San Francisco, CA. 91st AACR Annual Meeting, 2000. v. 41. p. 870-870.
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MANS, D. R. A. ; MAINO, M. ; SCHWARTSMANN, G. ; AB, R. ; LP, L. ; I, G. ; APF, C. ; AI, C. . Clinical and Cellular Pharmacologic Basis for Lack of Activity of 21-Day Continuous Topotecan in Patients with Advanced Pancreatic Carcinoma. In: 91st AACR Annual Meeting, 2000, San Francisco, CA. 91st AACR Annual Meeting, 2000. v. 41. p. 597-597.
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MANS, D. R. A. ; POSER, G. ; SCHRIPSEMA, J. ; FERRAZ, A. ; AB, R. ; SCHWARTSMANN, G. . Anti-Proliferative Effects of Substances Isolated from South-Brazilian Hypericum Species. In: 91st AACR Annual Meeting, 2000, San Francisco, CA. 91st AACR Annual Meeting, 2000. v. 41. p. 102-102.
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MANS, D. R. A. ; RAMOS, A. P. ; SILVA, K. ; SILVEIRA, J. D. ; I, G. ; AB, R. ; SCHWARTSMANN, G. . Lack of Genotoxicity of camptothecin (CPT), Topotecan (TPT), and Irinotecan (CPT-11) in a Prokaryotic and A Yeast Model. In: 91st AACR Annual Meeting, 2000, San Francisco, CA. 91st AACR Annual Meeting, 2000. v. 41. p. 178-178.
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MANS, D. R. A. ; AB, R. ; SCHWARTSMANN, G. ; G, L. . Radiosensitivity and Sphingolipid Metabolism in Human Glioblastoma Cell Lines. In: 91st AACR Annual Meeting, 2000. 91st AACR Annual Meeting. v. 41. p. 785-785.
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MANS, D. R. A. ; I, G. ; MOREIRA, J. ; G, S. . Differential Involvement of Excision Repair in the response og Human Colon Carcinoma Cell Lines to the Irinotecan - 5-Fluorouracil Combination. In: 91st AACR Annual Meeting, 2000. 91st AACR Annual Meeting, 2000. v. 414. p. 145-145.
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MANS, D. R. A. ; FERREIRA FILHO, A. ; AI, C. ; APF, C. ; SCHUNEMANN, H. ; LP, L. ; SCHWARTSMANN, G. . Clinical and Pharmacokinetic Study of Low-Dose, Three Times Daily Oral Etoposide in Patients with Advanced Malignancies. In: 91st AACR Annual Meeting, 2000, San Francisco, CA. 91st AACR Annual Meeting, 2000. v. 41. p. 606-606.
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MANS, D. R. A. ; RUSCHEL, C. R. A. M. D. M. V. ; SCHWARTSMANN, G. M. J. . reduction of the in vitro invasiveness of cultured human glioma cells through inhibition of ornithine decarboxylase (ODC) activity., 1999. Am Assoc Cancer Res - submitted and accepted for publication, 1999.
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MANS, D. R. A. ; RUSCHEL, C. R. A. M. D. ; BRAGA FILHO, A. M. J. ; SCHWARTSMANN, G. . Ionizing radiation-induced increase of protein kinase C (PKC) and ornithine decarboxylase (ODC) activities in human glioma cell lines., 1999. Am Assoc Cancer Res - submitted and accepted for publication, 1999.
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MANS, D. R. A. ; RUSCHEL, C. R. A. M. D. G. F. ; BRAGA FILHO, A. ; SCHWARTSMANN, G. . Ionizing radiation-mediated decrease of neutral sphingomyelinase (SMase) activity in cultured human glioma cells., 1999. Am Assoc Cancer Res - Submitted and accepted for publication, 1999.
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MANS, D. R. A. ; SCHWARTSMANN, G. M. D. W. L. R. A. . Cytotoxicity of the basic fibroblast growth factor (bFGF)-inhibiting agent pentosan polysulfate (PPS) in cultured in human adrenocortical carcinoma cells.. In: AACR, 1998. Proc Am Assoc Cancer Res, 1998. v. 39. p. 62.
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MANS, D. R. A. ; BRAGA FILHO, A. C. L. M. D. ; SCHWARSTMANN, G. C. L. C. L. . Radiosensitization of cultured human squamous esophageal carcinoma cells by taxotere (Txt) , gemcitabine(dFdC), and cisplatin (cDDP) .. In: AACR, 1998. Proc Am Assic Cancer Res Proc Am Assoc Cancer Res, 1998. v. 39. p. 381.
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MANS, D. R. A. ; SCHWARTSMANN, G. R. A. M. J. M. D. M. V. . Effects of modulation of protein kinase C (PKC) activity on basement membrane invasion by cultured human glioblastoma cells. In: AACR, 1998. Proc Am Assoc Cancer Res, 1998. v. 39. p. 492.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SPRINZ, E. ; STEFANI, S. ; LOITZENBAUER, B. L. L. ; BORTOLINI, M. ; KRONFELD, M. ; LOPES, G. ; SANDER, E. ; DRA, M. . Clinical and pharmacokinetic study of etoposide given orally three times daily to patients with AIDS-related Kaposis sarcoma (AIDS-KS).. In: ASCO, 1998. Proc Am Soc Clin Oncol, 1998. v. 17. p. 252a.
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MANS, D. R. A. ; MAINO, M. ; LAGO, S. M. D. L. L. ; SCHUNEMANN, H. A. J. P. P. ; KALAKUN, L. F. F. A. ; SCHWARTSMANN, G. . Phase II trial of a 21-day continuous infusion of topotecan in advanced pancreatic carcinoma: a SOAD trial.. In: ASCO, 1998. Proc Am Soc Clin oncol, 1998. v. 17. p. 295a.
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MANS, D. R. A. ; SANDER, E. ; CAMPOS JR, O. P. P. ; MONEGA, H. ; RIVOIRE, W. ; LOITZENBAUER, B. G. O. L. L. ; KALAKUN, L. ; DRA, M. . Phase II trial of cisplatin and decytabine in patients with advanced cervical cancer: a SOAD trial. In: ASCO, 1998. Proc Am Soc Clin Oncol, 1998. v. 17. p. 374a.
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MANS, D. R. A. ; SCHAPOVAL, A. L. C. ; MOTHES, B. ; SCHWARTSMANN, G. H. A. ; DRA, M. . Anticancer screening of South-Brazilian marine sponges, 1998. Ann Oncol, 1998. v. 9. p. 35.
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MANS, D. R. A. ; MONDIN, C. ; POSER, G. V. ; FERRAZ, A. M. D. ; LIMA, C. D. C. ; BARROS, M. L. R. ; VARELLA, D. R. A. ; CRAG, G. ; SCHWARTSMANN, G. . Targeted plant collection as a rational means to acquire candidate anticancer compounds for screening, 1998. Ann Oncol, 1998. v. 9. p. 35-2.
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MANS, D. R. A. ; G, S. ; DRA, M. ; LP, L. ; SANDER E, BORTOLINI M, VI APF CAMPOS JR. O . Phase I and pharmacokinetic study of etoposide given three times daily orally to patients with refractory solid tumors., 1998. Ann Oncol, 1998. v. 9. p. 66.
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MANS, D. R. A. ; RUSCHEL, C. R. A. M. D. F. V. ; SCHWARTSMANN, G. . Effects of ornithine decarboxylase (ODC) inhibition using D,L-alfa -difluoromethylornithine (DFMO), on the in vitro invasiveness of cultured human glioblastoma cells,, 1998. Ann Oncol, 1998. v. 9. p. 72.
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MANS, D. R. A. ; LERNER, C. ; MOTHES, B. S. E. ; RECH, E. P. L. C. J. ; AT, F. F. M. D. H. . Antimicrobial activity of sponges from Southern Brazil, Atlantic coast.. In: 5th International Sponge Symposium, 1998. Australia, 1998.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; HOROWITZ, M. ; SANDER, E. L. L. ; CAMPOS JR, O. ; SCHUNEMANN, H. F. F. A. ; DRA, V. M. C. A. M. . Phase I trial of the bombesin receptor antagonist RC-3095 in patients with refractory solid tumors., 1998. Ann Oncol, 1998. v. 9. p. 110.
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MANS, D. R. A. ; RUSCHEL, C. M. D. R. A. ; BRAGA FILHO, A. F. V. ; SCHWARTSMANN, G. . Radiosensitization of cultured human glioblastoma cells through inhibition of protein kinase C (PKC) activity., 1998. Ann Oncol, 1998. v. 9. p. 136.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; HOROWITZ, M. ; SANDER, E. L. L. ; CAMPOS JR, O. ; SCHUNEMANN, H. F. F. A. ; DRA, V. M. C. A. M. . Phase I trial of the bombesin receptor antagonist RC-3095 in patients with refractory solid tumors., 1998. Ann Oncol, 1998. v. 9. p. 136.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; CAMPOS JR, O. L. L. C. A. ; DRA, C. A. V. M. M. . Phase I and pharmacokinetic study of low-dose, three times daily, oral etoposide in patients with refractory solid tumors., 1998. Ann Oncol, 1998. v. 9. p. 138.
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MANS, D. R. A. ; SCHAPOVAL, E. L. C. ; MOTHES, B. ; SCHWARTSMANN, G. H. A. ; DRA, M. . Acquisition and anticancer screening in vitro of South-Brazilian marine sponges.. In: 17th International Cancer Congress, 1998. Proc 17th International Cancer Congress, 1998. p. 83.
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MANS, D. R. A. ; SCHWARTSMANN, G. R. A. M. D. M. J. M. V. . Modulation of protein kinase C (PKC) activity affects basement membrane invasion by cultured human glioblastoma cells.. In: 17th International Cancer Congress, 1998. Proc 17th International Cancer Congress, 1998. p. 479.
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MANS, D. R. A. ; BRAGA FILHO, A. C. L. M. D. ; SCHWARTSMANN, G. C. L. C. L. . Radiosensitization of cultured human epidermoid esophageal carcinoma cells by docetaxel, gemcitabine and cisplatin.. In: 17th International Cancer Congress, 1998. Proc 17th International Cancer Congress, 1998. v. 891.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; CAMPOS JR, O. ; SANDER, E. ; MONEGO, H. L. L. C. A. V. M. ; RIVOIRE, W. ; DRA, M. . Cisplatin plus decytabine, a novel DNA-hypomethylating agent, in pattients with advanced cervical cancer: a SOAD phase II trial.. In: 17th International Cancer Congress, 1998. Proc 17th International Cancer Congress, 1998. p. 1219.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SPRINZ, E. ; STEFANI, S. L. L. ; KRONFELD, M. ; DRA, C. A. V. M. C. A. M. . Clinical and pharmacokinetic study of etoposide given orally three times daily to patients with AIDS-related Kaposis sarcoms (AIDS-KS).. In: 17th International cancer Congress, 1998. Proc 17th International Cancer Congress, 1998. p. 1471.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; CAMPOS JR, O. L. L. C. A. ; SANDER, E. V. M. C. A. ; SCHUNEMANN, H. F. F. A. ; DRA, M. . Phase I and pharmacokinetic study of low-dose, three times daily, oral etoposide in patients with refractory solid tumors.. In: 17th International Cancer Congress, 1998. Proc 17th International Cancer Congress, 1998. p. 1481.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; HOROWITZ, M. ; SANDER, E. L. L. ; CAMPOS JR, O. ; SCHUNEMANN, H. F. F. A. ; DRA, V. M. C. A. M. . Clinical and pharmacokinetic study of RC-3095, an anti-bombesin agent, in patients with refractory solid tumors.. In: 17th International Cancer Congress, 1998. Proc 17th International Cancer Congress, 1998. p. 1481.
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MANS, D. R. A. ; FERRAZ, A. M. D. ; MONDIN, C. ; POSER, G. V. ; LIMA, C. ; BARROS, M. ; SCHWARTSMANN, G. L. R. D. C. R. A. . Acquisition of candidate anticancer agents throught targeted plant collection. In: 17th international Cancer Congress, 1998. Proc 17th International Cancer Congress, 1998. p. 1481.
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MANS, D. R. A. ; SCHWARTSMANN, G. M. D. V. P. ; JCF, M. . Antitumor effects of the basic fibroblast growth factor-inhibiting agent pentosan polysulfate (PPS) in the SW-13 human adrenocortical carcincoma cell lina.. In: XXVII Reunião Anual da Sociedade de Bioquímica e Biologia Molecular (SBBq), 1998. (SBBq) Caxambu, MG Resumos. Caxambu - MG, 1998. p. 160.
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MANS, D. R. A. ; BRAGA FILHO, A. C. L. M. D. ; SCHWARTSMANN, G. C. L. C. L. ; JCF, M. . Taxotere, gemcitabine, and cisplatin as radiosensitizers in human esophageal squamous carcinoma cell lines.. In: XXVII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular., 1998. (SBBq) Caxambu, MG Resumos. Caxambu - MG, 1998. p. 160.
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MANS, D. R. A. ; CAMPOS JR, O. L. L. M. D. V. M. ; BORTOLINI, M. C. A. ; SCHWARTSMANN, G. C. A. ; JCF, M. . A phase I and pharmacokinetic study of fractioned, low-dose, oral etoposide in patients with drug-refractory solid tumors.. In: XXVII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1998. (SBBq) Caxambu, MG- Resumos. Caxambu - MG, 1998. p. 160.
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MANS, D. R. A. ; RAIMANN, P. ; SCWARTSMANN, G. M. D. ; EA, B. . Effects of D,L-buthionine-S,R-sulfoximine, verapamil, and methylguanine on decarbazine and carmustine cytotoxicity in human melanoma cell lines.. In: XXVII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular(SBBq), 1998. (SBBq) Caxambu - MG Resumos. Caxambu - MG, 1998. p. 160.
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MANS, D. R. A. ; RUSCHEL, C. R. A. M. D. ; SCHWARTSMANN, G. ; EA, B. . Increased radiosensitivity of cultured human glioblastoma cells through inhibition of protein kinase C activity. In: XXVII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1998. (SBBq) Caxambu MG - Resumos. Caxambu - MG, 1998. p. 85.
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MANS, D. R. A. ; SCWARTSMANN, G. F. D. M. D. ; JCF, M. . Biochemical Modulation of teniposide (VM-26) cytotoxicity in human renal cell carcinoma (RCC) cell lines.. In: XXVII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq), 1998. (SBBq) Caxambu - MG - Resumos. Caxambu - MG, 1998. p. 160.
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MANS, D. R. A. ; JCF, F. V. R. A. M. D. F. C. M. . Effects of inhibition of ornithine decarboxylase activity on basement membrane invasion by cultured human glioblastoma cells.. In: XXVII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1998. Caxambu, MG, Resumos. Caxambu - MG, 1998. p. 84.
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MANS, D. R. A. ; RUSCHEL, C. ; SCHWARTSMANN, G. R. A. M. J. M. D. ; EA, B. . Functional association of protein kinase C activity and ornithine decarboxylase activity in human glioblastoma cell lines.. In: XXVII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular, 1998. (SBBq) - Caxambu MG - Resumos. Caxambu - MG, 1998. p. 90.
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MANS, D. R. A. ; GRIVICICH, I. ; SCHWARTSMANN, G. M. D. ; JCF, M. . Sequence-dependent cytotoxicity of the irinotecan(CPT-11) - 5 fluorouracil (5-FU) combination in human colon carcinoma cell lines.. In: XXVII Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular(SBBq), 1998. (SBBq) Caxambu - MG Resumos. Caxambu - MG, 1998. p. 160.
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MANS, D. R. A. ; FERRAZ, A. ; STAATS, C. ; BORDIGNON, S. ; MONDIN, C. ; BARROS, M. ; DIEL, C. ; LIMA, C. ; LOPES, R. ; SCHWARTSMANN, G. ; GL, M. D. V. P. . Atividade anti[roliferativa in vitro de Hypericum caprifoliatum Chan et Schlecht.. In: XV Simpósio de Plantas Medicinais do Brasil, 1998. Águas de Lindóia - SP, 1998.
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MANS, D. R. A. ; SCHWARTSMANN, G. S. M. M. D. . In vitro evaluation of the basic fibroblast growth factor (bFGF)-inhibiting agent pentosan polysulfate (PPS) in prostatic carcinoma cell lines.. In: AACR, 1997. Proc Am Assoc Cancer Res, 1997. v. 38. p. 57.
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MANS, D. R. A. ; AB, R. ; JCF, M. ; DRA, M. . Relationship between protein kinase C (PKC)-mediated cytotoxicity and ornithine decarboxylase activity in cultured human glioblastoma cells.. In: AACR, 1997. Proc Am Assoc Cancer Res, 1997. v. 38. p. 231.
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MANS, D. R. A. ; GRIVICICH, I. ; SCHWARTSMANN, G. M. D. R. A. C. H. . The sequence - dependent cytotoxicicty of the irinotecan (CPT-11) - 5 fluorouracil (5-FU)combination in human colon carcinoma cell lines is due to the sequence -dependent introduction of DNA lesiond.. In: AACR, 1997. Proc Am Assoc cancer Res, 1997. v. 38. p. 318.
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MANS, D. R. A. ; SCHWARTSMANN, G. M. D. R. A. F. D. . Improved efficacy of teniposide (VM-26) in renal cell carcinoma (RCC) cell lines upon proper scheduling and modulation.. In: AACR, 1997. Proc Am Assoc Cancer Res, 1997. v. 38. p. 607.
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MANS, D. R. A. ; RAIMANN, P. ; EA, M. D. B. . Activity of the basic fibroblast growth factor-inhibiting heparinoid pentosan polysulfate in a human malignant melanoma cell line. In: XXVI Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq), 1997. SBBq- Caxambu, MG. Resumos. Caxambu - MG, 1997. p. 80.
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MANS, D. R. A. ; WASKOW, L. M. D. ; GRIVICICH, I. S. M. ; SCHWARTSMANN, G. R. A. . Antitumor efficacy of the basic fibroblast growth factor-inhibiting heparinoid pentosan polysulfate (PPS) SW-13 human adrenocortical carcinoma cell line.. In: 43 Congresso Nacional de Genética, 1997. Brazilian J Genetics. Goiânia - GO, 1997. v. 20.
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MANS, D. R. A. ; SCHWARTSMANN, G. M. D. R. A. S. C. . Assesment of the efficacy of the irinotecan (CPT-11) - 5-fluorouracil (5-FU) combination in a panel of human colon carcinoma cell lines.. In: AACR, 1996. Proc Am Assoc Cancer Res, 1996. v. 37. p. 291.
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MANS, D. R. A. ; LOPES JR, G. R. A. M. D. B. E. L. ; SCHWARTSMANN, G. . Inhibition of protein kinase C (PKC) activity by tamoxifen (Tmx) in cultured human glioma cells.. In: AACR, 1996. Proc Am Assoc Cancer Res, 1996. v. 37. p. 423.
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MANS, D. R. A. ; DRA, M. ; AB, R. ; I, G. ; COSTA, D. ; HS, S. G. . The cytotoxicity of the irinotecan (CPT-11) - 5-fluorouracil (5-FU) combination in human colon carcinoma cell lines is sequence-dependent, 1996. Ann Oncol, 1996. v. 7. p. 9-10.
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MANS, D. R. A. ; LOPES JR, G. R. A. M. D. B. E. L. ; SCHWARTSMANN, G. . Tamoxifen (Tmx) citotoxicity against human glioblastoma cell lines is mediated by inhibition of plasma membrane-associated, but not cytosolic protein kinase C (PKC) activity., 1996. Ann Oncol, 1996. v. 7. p. 9.
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MANS, D. R. A. . In vitro antitumor efficaccy of teniposide (VM-26) versus vinblastine (Vbl) against renal cell carcinoma (RCC), and effects on drug cytotoxicity of schedule and chemo-modulation., 1996, 1996.
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MANS, D. R. A. ; LOPES JR, G. R. A. M. D. B. E. L. ; SCHWARTSMANN, G. . Tamoxifen exerts its cytotoxicity in human glioma cell lines by inhibiting protein kinase C activity.. In: XXV Reunião da Sociedade Brasileeira de Bioquímica e Biologia Molecular (SBBq), 1996. SBBq, Caxambu, MG. Resumos. Caxambu - MG, 1996. p. 84.
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MANS, D. R. A. ; LIMA, C. M. D. R. A. F. D. ; SCHWARTSMANN, G. . Antitumor efficacy of teniposide versus vinblastine in a kidney cancer cell line, and effects on drug cytotoxicity of schedule and chemomodulation. In: XXV Reunião Anual da Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq), 1996. SSBq - Caxambu - MG Resumos. Caxambu - MG, 1996. v. 85.
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MANS, D. R. A. ; LOPES JR, G. R. A. M. D. B. E. L. ; SCHWARTSMANN, G. . Tamoxifen cytotoxicity in cultured human glioblastoma cells involves inhibition of protein kinase C activity. In: IX Brazilian Congress of Cell Biology, 1996. Brazilian J Morphological Sciences. Águas de Lindóia - SP, 1996. v. 13. p. 69.
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MANS, D. R. A. ; GRIVICICH, I. M. D. R. A. ; SCHWARTSMANN, G. D. C. H. . Sequence-dependence of the cytotoxicity of the irinotecan -5-fluorouracil combination in human colon carcinoma cell lines.. In: IX Brazilian Congress of Cell Biology, 1996. Brazilian J Morphological Sciences. Águas de Lindóia - SP, 1996. v. 13. p. 70.
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MANS, D. R. A. ; LIMA, C. M. D. R. A. F. D. ; SCHWARTSMANN, G. . Comparison of the antitumor efficacy of teniposide with that of vinblastine in cultured kidney cancer cells:a biochemical and in vitro study.. In: IX Brazilian Congress of Cell Biology, 1996. Brazilian J morphological Sciences. Águas de Lindóia - SP, 1996. v. 13. p. 70.
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MANS, D. R. A. ; CAPRA, M. M. D. R. A. ; GRIVICICH, I. ; SCHWARTSMANN, G. . Assesment of the efficacy of topotecan in pancreatic carcinoma: an in vitro potency-comparing study.. In: IX Brazilian Congress of Cell Biology, 1996. Brazilian J Morphological Sciences. Águas de Lindóia - SP, 1996. v. 13. p. 73.
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MANS, D. R. A. ; MALCON, C. M. D. ; BECKER, D. ; GRIVICICH, I. ; LOPES JR, G. L. ; SCALETZKY, A. M. V. ; SCHWARTSMANN, G. P. P. J. F. . High-dose tamoxifen interferes with etoposide disposition in the cerebrospinal fluid of glioma patients and P-glycoprotein-overexpressing tissues in rats.. In: AACR, 1995. Proc Am Assoc Cancer Res, 1995. v. 36. p. 295.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; BECKER, D. M. D. M. V. ; GRIVICICH, I. ; SCHUNEMANN, H. ; SCALETZKY, A. P. P. G. M. ; KALAKUN, L. J. F. B. A. . Enhanced disposition of etoposide (VP-16) in the cerebrospinal fluid (CSF) by high-dose tamoxifen (Tmx) in patients (pts) with progressive malignant gliomas.. In: ASCO, 1995. Proc Am Soc Clin Oncol, 1995. v. 14. p. 152.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SANDER, E. M. D. M. V. ; SPRINZ, E. ; KALAKUN, L. . Phase II study of the basic fibroblast growth factor (b-FGF)-inhibiting agent pentosan polysulfate (PPS) in patients with AIDS-related Kaposis sarcoma (AIDS-KS). In: ASCO, 1995. Proc Am Soc Clin Oncol, 1995. v. 14. p. 290.
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MANS, D. R. A. ; LOPES JR, G. R. A. M. D. L. ; SCHWARTSMANN, G. . Assesment of the mechanism of action of tamoxifen-containing combinations in a panel of glioblastoma cell lines.. In: IX Congresso de Oncologia Clínica, 1995. Oncologia Atual MG. Belo Horizonte - MG, 1995. p. 8.
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MANS, D. R. A. ; SCHWARTSMANN, G. M. D. R. A. V. M. S. C. . Assesment of the efficacy of the 5-fluorouracil/CPT-11 combination in a panel of human colon carcinoma cell lines.. In: IX Congresso Brasileiro de Oncologia Clínica, 1995. Oncologia Atual MG. Belo Horizonte - MG, 1995. p. 80.
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MANS, D. R. A. ; CAPRA, M. M. D. R. A. ; GRIVICICH, I. ; SCHWARTSMANN, G. . Assesment of the efficacy of topotecan in pancreatic carcinoma: an in vivo feasibility study. In: IX Congresso Brasileiro de Oncologia Clínica, 1995. Oncologia Atual MG. Belo Horizonte - MG, 1995. p. 81.
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MANS, D. R. A. ; GRIVICICH, I. M. D. K. M. R. A. ; ELISABETSKY, E. ; HARRAP, K. K. L. G. O. ; SCHWARTSMANN, G. . Extrato oriundo da Mata Atlântica, SOAD 932, possui atividade citotóxica em linhas de carcinoma de ovário humano resistentes a cisplatinum e doxorrubicina.. In: IX Congresso Brasilerio de Oncologia Clínica, 1995. Oncologia Atual MG. Belo Horizonte - MG, 1995. p. 111.
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MANS, D. R. A. ; SPRINZ, E. M. D. ; SANDER, E. ; KALAKUN, L. ; PROLLA, G. J. F. ; SCHWARTSMANN, G. . A phase II study of oral etoposide (VP16) in AIDS-related Kaposis sarcoma.. In: Tenth International Conference on AIDS, 1994. Tenth International Conference on AIDS. Abstract Book, 1994. v. I. p. 118.
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MANS, D. R. A. ; KALAKUN, L. ; SCHWARTSMANN, G. S. V. M. D. . Monitoring role of the nurse in a phase II trial with non-small cell lung cancer.. In: Third National Conference on Cancer Nursing Research, 1994. Third National Conference on Cancer Nursing Research, 1994. v. 7-D.
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MANS, D. R. A. ; SCALETZKY, A. M. D. ; BECKER, D. ; BITTAR, C. O. J. P. C. ; LEYVA, A. J. F. R. J. M. V. F. F. A. ; SCHWARTSMANN, G. . Excessive 5-fluorouracil (5-FU)-related toxicities in patients (pts) with defective pyrimidine carabolism. In: ASCO, 1994. Proc Am Soc Clin Oncol, 1994. v. 13. p. 76.
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MANS, D. R. A. ; BECKER, D. M. D. ; PROLLA, G. ; SNADER, E. M. V. J. F. ; KALAKUN, L. ; SPRINZ, E. ; SCHWARTSMANN, G. B. A. . Plasma pharmacokinetics of low-dose oral etoposide (VP-16) in patients (pts) with advanced AIDS-associated Kaposis sarcoma (AIDS-KS). In: ASCO, 1994. Proc Am Soc Clin Oncol, 1994. v. 13. p. 189.
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MANS, D. R. A. ; SPRINZ, E. ; KALAKUN, L. ; PROLLA, G. ; SANDER, E. M. V. ; YAMAGUSHI, N. M. D. ; SCHWARTSMANN, G. . A phase II study of the basic fibroblastt growth factor (b-FGF)-inhibiting agent pentosan polysulfate (PPS) in patients (pts) with AIDS-related kaposis sarcoma (AIDS-KS), 1994. Ann Oncol, 1994. v. 5. p. 3.
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MANS, D. R. A. ; PROLLA, G. M. D. ; SANDER, E. ; BECKER, D. ; KALAKUN, L. M. V. J. F. ; SPRINZ, E. ; SCHWARTSMANN, G. B. A. . A phase II and plasma pharmacokinetic study of low-dose, oral etoposide (VP-16) in advanced AIDS-associated Kaposiss sarcoma (AIDS-KS), 1994. Ann Oncol, 1994. v. 5. p. 5.
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MANS, D. R. A. ; MALCON, C. M. D. ; LOPES JR, G. L. ; BECKER, D. ; SCHWARTSMANN, G. . Altered disposition of etoposide (VP-16) by tamoxifen (Tmx) in P-glycoprotein (P-gp)-containing tissues in rats., 1994. Ann Oncol, 1994. v. 5. p. 7.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SCALETZKY, A. ; POHLMANN, P. ; BECKER, D. J. F. ; DRA, G. M. M. . Enhanced etoposide (VP-16) retention in the cerebrospinal fluid (CSF) by high-dose tamoxifen (Tmx)., 1994. Ann Oncol, 1994. v. 5. p. 13.
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MANS, D. R. A. ; SCALETZKY, A. ; KOYA, R. G. M. ; SCHUNEMANN, H. ; KALAKUN, L. ; SCHWARTSMANN, G. F. F. A. M. V. M. D. . A phase II study of BCNU plus verapamil in patients with advanced colorectal carcinoma, 1994. Ann Oncol, 1994. v. 5. p. 50.
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MANS, D. R. A. ; G, S. ; A, S. ; MJC, G. ; L, P. L. ; M, T. ; C, G. ; L, M. D. J. K. . A phase II trial of interleukin -2 (IL-2) plus alpha-interferon (IFN) administered subcutaneously (sc) in patients with metastatic malignant melanoma (MMM)., 1994. Ann Oncol, 1994. v. 5. p. 176.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; BECKER, D. M. D. ; BORDIGNON, S. ; SCHENKEL, E. K. M. ; KR, G. O. K. L. H. . South American Office for Anticancer Drug Development (SOAD) : strategies to identify new anticancer drugs from natural products, 1994. Ann Oncol, 1994. v. 5. p. 181.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SCALETZKY, A. ; SCHUNEMANN, H. G. M. ; KALAKUN, L. B. A. ; MENKE, C. M. D. . Clinical toxicity of taxol given as a one-hour intravenous (IV) infusion in patients with solid tumors., 1994. Ann Oncol, 1994. v. 5. p. 187.
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MANS, D. R. A. ; SCALETZKY, A. M. D. ; BECKER, D. ; BITTAR, C. O. J. O. C. ; LEYVA, A. F. F. A. M. V. R. J. J. F. ; SCHWARTSMANN, G. . Two new cases of hyperpirimidinuria associated with excessive 5-fluorouracil toxicity., 1994. Ann. Oncol., 1994. v. 5. p. 193.
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MANS, D. R. A. ; SCHWARTSMANN, G. R. A. M. D. B. E. . Tamoxifen cytotoxicity against human glioblastoma cell lines is mediated by inhibition of plasma membrane-associated conventional protein kinase C (cPKC) isoforms, 1994, 1994.
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MANS, D. R. A. ; TORRES, G. M. M. ; DRA, M. . Câncer oral: uma análise baseada em 3518 casos de lesões orais no Hospital de Clínicas de Porto Alegre. In: Simpósio Internacional de Biomedicina: presente e futuro, 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; MALCOM, C. M. D. ; LOPES JR, G. L. ; BECKER, D. ; SCHWARTSMANN, G. . Altered disposition of etoposide (VP-16) by tamoxifen (Tmx) in P-glycoprotein (P-gp)-containing tissues in rats.. In: Simpósio Internacional de Biomedicina: presente e futuro., 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SCALETZKY, A. ; BECKER, D. P. P. J. F. ; DRA, G. M. M. . Enhanced etoposide (VP-16) retention in the cerebrospinal fluid (CSF) by high-dose tamoxifen (Tmx).. In: Simpósio Internacional de Biomedicina: presente e futuro, 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; BECKER, D. M. D. ; BORDIGNON, S. ; SCHWARTSMANN, G. C. K. M. G. O. K. L. H. K. . South-American Office for Anticancer Drug Development (SOAD): strategies to identify new anticancer agents.. In: Simpósio Internacional de Biomedicina: presente e futuro, 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; PROLLA, G. M. D. ; SANDER, E. ; BECKER, D. ; KALAKUN, L. M. V. J. F. ; SPRINZ, E. ; SCHWARTSMANN, G. B. A. . Estudo de fase II e farmacocinética com etoposide oral em pacientes com sarcoma de kaposi associado à SIDA.. In: XIII Congresso Brasileiro de Cancerologia, 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SCALETZKY, A. ; BECKER, D. J. F. ; PAGLIOLI, E. G. M. M. V. P. P. ; OPPITZ, P. ; DRA, B. A. M. . Farmacocinética do etoposide no líquido céfalo-raquidiano (LCR) de pacientes com gliomas refratários na presença de tamoxifeno.. In: XIII Congresso Brasileiro de Cancerologia, 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SCALETZKY, A. ; BECKER, D. J. F. ; PAGLIOLI, E. G. M. M. V. P. P. ; OPPITZ, P. ; DRA, B. A. M. . Farmacocinética do etoposide no líquido céfalo-raquidiano (LCR) de pacientes com glioma refratário na presença de tamoxifeno.. In: XIII Congresso Brasileiro de Cancerologia, 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; BECKER, D. M. D. ; BORDIGNON, S. ; SCHENKEL, E. C. K. M. ; KR, G. O. K. L. H. . Identificação de novos agentes antineoplásicos a partir de produtos naturais: experiência da SOAD. In: XIII Congresso Brasileiro de Cancerologia, 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; BITTENCOURT, H. F. F. A. ; JOB, F. M. D. ; BARRIOS, C. . Uso do etoposide (VP-16) via oral em baixas doses no tratamento paliativo de neoplasias hematológicas.. In: XIII Congresso Brasileiro de Cancerologia, 1994. Porto Alegre - RS, 1994.
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MANS, D. R. A. ; SCHWARTSMANN, G. ; SANDER, E. ; PROLLA, G. ; SPRINZ, E. ; ZAMPEZE, M. ; VINHOLES, J. ; KRONFELD, M. J. F. ; KALAKUN, L. ; AL, M. D. B. . Phase II trial of pentosan polysulfate (PPS) in patients (pts) with AIDS-related kaposis sarcoma (KS). In: ASCO, 1993. Proc Am Soc Clin Oncol., 1993. v. 12. p. 54.
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MANS, D. R. A. ; SANDER, E. ; ZAMPESE, M. ; PROLLA, G. ; MARQUEZ, A. ; SPRINZ, E. J. F. V. L. ; KRONFELD, M. ; KALAKUN, L. ; SCHWARTSMANN, G. M. D. B. A. . Phase II trial of low-dose oral etoposide in AIDS-related kaposis sarcoma. In: ASCO, 1993. Proc Am Soc Clin Oncol, 1993. v. 12. p. 54.
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MANS, D. R. A. ; KALAKUN, L. M. D. ; SCHOLEM, V. ; SCALETZKY, A. J. F. M. V. ; PIZÃO, P. ; SCHWARTSMANN, G. B. A. . South-American Office for Anticancer Drug Development (SOAD): estratégias para a identificação de novas drogas anticâncer.. In: 8 Congresso brasileiro de Oncologia Clínica, 1993. São Paulo - SP, 1993.
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MANS, D. R. A. ; KALAKUN, L. ; SANDER, E. ; SPRINZ, E. ; PROLLA, G. ; ZAMPEZE, M. ; DRA, J. F. M. . Estudo de fase II com polisulfato de pentosan (PPS), um inibidor do fator de estimulação de fibroblastos (b-FgF) em sarcoma de kaposi associada a SIDA (SK-SIDA). In: 8 Congresso Brasileiro de Oncologia Clínica, 1993. São Paulo - SP, 1993.
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MANS, D. R. A. ; MARRONI, B. ; KALAKUN, L. ; LUDWIG, E. M. D. ; SCHWARTSMANN, G. . Interferon alfa modula a expressão de antígenos e favorece a localização de metástases de melanoma maligno humano (MMH) com anticorpo monoclonal marcado com tecnecium.. In: 8 Congresso Brasileiro de Oncologia Clínica, 1993. São Paulo - SP, 1993.
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MANS, D. R. A. ; SPRINZ ; SANDER ; L, K. ; G, P. ; M, Z. ; FA, J. ; DRA, M. ; V, S. ; N, S. G. . Estudo de fase II com etoposide oral em baixa dose para sarcoma de kaposi associado a SIDA (SK-SIDA).. In: 8 Congresso Brasileiro de Oncologia Clínica, 1993. São Paulo - SP, 1993.
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MANS, D. R. A. ; MCGILL, A. G. L. M. D. ; AL, P. C. B. . Nívies de VMA (ácido vanilmandélico) em pacientes com neuroblastoma (NB): coleta de urina de 24 h x amostra aleatória (AA).. In: X Congresso da Sociedade Latino Americana de Oncologia Pediátrica, 1993. Rio de Janeiro, RJ, 1993.
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MANS, D. R. A. ; RETÈL, J. M. D. V. M. J. L. M. V. S. M. ; LANKELMA, J. . Role of the semi-quinone free radical of VP-16-213 in the inactivation of single-stranded (ss) X174 DNA. In: AACR, 1989. Proc Am Assoc Cancer Res, 1989. v. 30. p. 489.
Histórico profissional
Endereço profissional
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Universidade Luterana do Brasil. , Rua Miguel Tostes, 101, Sao Luis, 92420280 - Canoas, RS - Brasil, Telefone: (51) 4779219, Fax: (51) 4781747, URL da Homepage:
Experiência profissional
1999 - Atual
Universidade Luterana do BrasilVínculo: Servidor público ou celetista, Enquadramento Funcional: Pesquisador, Carga horária: 40
Atividades
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07/1999
Pesquisa e desenvolvimento , Privado, Campus Canoas.,Linhas de pesquisa
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Ensino, Medicina, Nível: Pós-Graduação,Disciplinas ministradas, Biologia Molecular
1993 - Atual
Hospital de Clínicas de Porto AlegreVínculo: Professor Visitante, Enquadramento Funcional: Contrato, Carga horária: 30
Atividades
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Pesquisa e desenvolvimento .,Linhas de pesquisa
1993 - Atual
Universidade Federal do Rio Grande do SulVínculo: Professor Visitante, Enquadramento Funcional: Outro, Carga horária: 4
Atividades
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Ensino, Ciências Biológicas (Bioquimica), Nível: Pós-Graduação,Disciplinas ministradas, Biologia Molecular de Tumores
Criando um monitoramento
Nossos robôs irão buscar nos nossos bancos de dados todos os processos de Dennis Ricardo August Mans e sempre que o nome aparecer em publicações dos Diários Oficiais, avisaremos por e-mail e pelo painel do usuário
Criando um monitoramento
Nossos robôs irão buscar nos nossos bancos de dados todas as movimentações desse processo e sempre que o processo aparecer em publicações dos Diários Oficiais e nos Tribunais, avisaremos por e-mail e pelo painel do usuário
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