Amanda Edling de Barros

Idiomas

Projetos de pesquisa

• 2023 - 2024

  Study of the genome biology of Sinorhizobium meliloti in free living condition and symbiosis with legume plants Medicago sativa, Descrição: The study focuses on the symbiotic relationship between Sinorhizobium meliloti and Medicago sativa, highlighting the advantages of symbiosis in nitrogen-deficient soils. The cell cycle of the alphaproteobacterium S. meliloti is characterized by the formation of two distinct cell typessmall and largeeach with specific capabilities related to DNA replication and cell division. The process of bacterial infection in the host involves signal exchange, with legumes releasing flavonoids to signal S. meliloti. Following internalization, the bacteria undergo differentiation into bacteroids, capable of converting atmospheric nitrogen into ammonia. The compaction of bacterial chromosomes within the nodule is considered essential, involving nucleoid-associated proteins (NAPs) and structural maintenance of chromosomes (SMC) proteins. The project aims to investigate the hypothesis that genome compaction within the nodule structure plays a crucial role in reprogramming the bacteroids during symbiosis.. , Situação: Concluído; Natureza: Pesquisa. , Alunos envolvidos: Mestrado acadêmico: (1) Doutorado: (1) . , Integrantes: Amanda Edling de Barros - Coordenador / Sara Dendene - Integrante., Financiador(es): Institute for Integrative Biology of the Cell - Bolsa.