Rodrigo Malavazi Corder

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Produções bibliográficas

• RIBEIRO, ADÈLE HELENA ; SOLER, JÚLIA M. P. ; CORDER, RODRIGO M. ; FERREIRA, MARCELO U. ; HEIDER, DOMINIK . From bites to bytes: understanding how and why individual malaria risk varies using artificial intelligence and causal inference. Frontiers in Genetics , v. 16, p. 1599826, 2025.

• MONTALBÁN, ANTONIO ; CORDER, RODRIGO M. . The spark of synchronization in heterogeneous networks of chaotic maps. CHAOS (WOODBURY, N.Y. ONLINE) , v. 34, p. 021101, 2024.

• FONTOURA, PABLO S ; MACEDO, EVELYN G ; CALIL, PRISCILA R ; CORDER, RODRIGO M ; RODRIGUES, PRISCILA T ; TONINI, JULIANA ; ESQUIVEL, FABIANA D ; LADEIA, WINNI A ; FERNANDES, ANDERSON R J ; JOHANSEN, IGOR C ; SILVA, MARCOS F ; FERNANDES, AMANDA O S ; LADEIA-ANDRADE, SIMONE ; CASTRO, MARCIA C ; FERREIRA, MARCELO U . Changing Clinical Epidemiology of Malaria as Transmission Decreases: Population-Based Prospective Panel Survey in the Brazilian Amazon. J INFECT DIS , v. 229, p. 947-958, 2024.

• GARCIA CASTILLO, STEFANO S. ; ABANTO ALVAREZ, CAROLINE ; ROSAS-AGUIRRE, ÁNGEL ; ACOSTA, CARLOS ; CORDER, RODRIGO M. ; GÓMEZ, JOAQUÍN ; GUZMÁN, MITCHEL ; SPEYBROECK, NIKO ; LLANOS-CUENTAS, ALEJANDRO ; CASTRO, MARCIA C. ; ROSANAS-URGELL, ANNA ; FERREIRA, MARCELO U. ; VINETZ, JOSEPH M. ; GAMBOA, DIONICIA ; TORRES, KATHERINE . Recurrence patterns and evolution of submicroscopic and asymptomatic Plasmodium vivax infections in malaria-endemic areas of the Peruvian Amazon. PLoS Neglected Tropical Diseases , v. 18, p. e0012566, 2024.

• AURADKAR, ANKUSH ; CORDER, RODRIGO M. ; MARSHALL, JOHN M. ; BIER, ETHAN . A self-eliminating allelic-drive reverses insecticide resistance in Drosophila leaving no transgene in the population. Nature Communications , v. 15, p. 9961, 2024.

• TIKHE, CHINMAY V. ; ISSIAKA, SARE ; DONG, YUEMEI ; KEFI, MARY ; TAVADIA, MIHRA ; BILGO, ETIENNE ; CORDER, RODRIGO M. ; MARSHALL, JOHN ; DIABATE, ABDOULAYE ; DIMOPOULOS, GEORGE . biopesticide overcomes insecticide resistance in malaria vector mosquitoes. SCIENCE ADVANCES , v. 10, p. eads3658, 2024.

• RODRIGUES, PRISCILA T. ; JOHANSEN, IGOR C. ; LADEIA, WINNI A. ; ESQUIVEL, FABIANA D. ; CORDER, RODRIGO M. ; TONINI, JULIANA ; CALIL, PRISCILA R. ; FERNANDES, ANDERSON R.J. ; FONTOURA, PABLO S. ; CAVASINI, CARLOS E. ; VINETZ, JOSEPH M. ; CASTRO, MARCIA C. ; FERREIRA, MARCELO U. . Lower Microscopy Sensitivity with Decreasing Malaria Prevalence in the Urban Amazon Region, Brazil, 2018-2021. EMERGING INFECTIOUS DISEASES (ONLINE) , v. 30, p. 1884-1894, 2024.

• CORDER, RODRIGO M. ; AREZ, ANA PAULA ; FERREIRA, MARCELO U. . Individual variation in Plasmodium vivax malaria risk: Are repeatedly infected people just unlucky?. PLoS Neglected Tropical Diseases , v. 17, p. e0011020, 2023.

• SMIDLER, ANDREA L. ; PAI, JAMES J. ; APTE, REEMA A. ; SÁNCHEZ C., HÉCTOR M. ; CORDER, RODRIGO M. ; JEFFREY GUTIÉRREZ, EILEEN ; THAKRE, NEHA ; ANTOSHECHKIN, IGOR ; MARSHALL, JOHN M. ; AKBARI, OMAR S. . A confinable female-lethal population suppression system in the malaria vector,. SCIENCE ADVANCES , v. 9, p. eade8903, 2023.

• CARBALLAR-LEJARAZÚ, REBECA ; DONG, YUEMEI ; PHAM, THAI BINH ; TUSHAR, TAYLOR ; CORDER, RODRIGO M. ; MONDAL, AGASTYA ; SÁNCHEZ C., HÉCTOR M. ; LEE, HSU-FENG ; MARSHALL, JOHN M. ; DIMOPOULOS, GEORGE ; JAMES, ANTHONY A. . Dual effector population modification gene-drive strains of the African malaria mosquitoes, and. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (ONLINE) , v. 120, p. e2221118120, 2023.

• CORDER, RODRIGO M. ; BIAN, ZHENG ; PEREIRA, TIAGO ; MONTALBÁN, ANTONIO . Emergence of chaotic cluster synchronization in heterogeneous networks. CHAOS (WOODBURY, N.Y. ONLINE) , v. 33, p. 091103, 2023.

• NICOLETE, VANESSA C. ; RODRIGUES, PRISCILA T. ; FERNANDES, ANDERSON R.J. ; CORDER, RODRIGO M. ; TONINI, JULIANA ; BUSS, LEWIS F. ; SALES, FLÁVIA C. ; FARIA, NUNO R. ; SABINO, ESTER C. ; CASTRO, MARCIA C. ; FERREIRA, MARCELO U. . Epidemiology of COVID-19 after Emergence of SARS-CoV-2 Gamma Variant, Brazilian Amazon, 2020-2021. EMERGING INFECTIOUS DISEASES (ONLINE) , v. 28, p. 709-712, 2022.

• GOMES, M. GABRIELA M. ; FERREIRA, MARCELO U. ; CORDER, RODRIGO M. ; KING, JESSICA G. ; SOUTO-MAIOR, CAETANO ; PENHA-GONÇALVES, CARLOS ; GONÇALVES, GUILHERME ; CHIKINA, MARIA ; PEGDEN, WESLEY ; AGUAS, RICARDO . Individual variation in susceptibility or exposure to SARS-CoV-2 lowers the herd immunity threshold. JOURNAL OF THEORETICAL BIOLOGY , v. 540, p. 111063, 2022.

• MONTALBÁN, ANTONIO ; CORDER, RODRIGO M. ; GOMES, M. GABRIELA M. . Herd immunity under individual variation and reinfection. Journal of Mathematical Biology , v. 85, p. 2, 2022.

• KANDUL, NIKOLAY P. ; LIU, JUNRU ; BUCHMAN, ANNA ; SHRINER, ISAIAH C. ; CORDER, RODRIGO M. ; WARSINGER-PEPE, NATALIE ; YANG, TING ; YADAV, AMARISH K. ; SCOTT, MAXWELL J. ; MARSHALL, JOHN M. ; AKBARI, OMAR S. . Precision Guided Sterile Males Suppress Populations of an Invasive Crop Pest. GEN Biotechnology , v. 1, p. 372-385, 2022.

• TORRES, KATHERINE ; FERREIRA, MARCELO U. ; CASTRO, MARCIA C. ; ESCALANTE, ANANIAS A. ; CONN, JAN E. ; VILLASIS, ELIZABETH ; DA SILVA ARAUJO, MAISA ; ALMEIDA, GREGORIO ; RODRIGUES, PRISCILA T. ; CORDER, RODRIGO M. ; FERNANDES, ANDERSON R. J. ; CALIL, PRISCILA R. ; LADEIA, WINNI A. ; GARCIA-CASTILLO, STEFANO S. ; GOMEZ, JOAQUIN ; DO VALLE ANTONELLI, LIS RIBEIRO ; GAZZINELLI, RICARDO T. ; GOLENBOCK, DOUGLAS T. ; LLANOS-CUENTAS, ALEJANDRO ; GAMBOA, DIONICIA ; et.al . Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE , v. 107, p. 168-181, 2022.

• FERREIRA, MARCELO U. ; CORDER, RODRIGO M. ; JOHANSEN, IGOR C. ; KATTENBERG, JOHANNA H. ; MORENO, MARTA ; ROSAS-AGUIRRE, ANGEL ; LADEIA-ANDRADE, SIMONE ; CONN, JAN E. ; LLANOS-CUENTAS, ALEJANDRO ; GAMBOA, DIONICIA ; ROSANAS-URGELL, ANNA ; VINETZ, JOSEPH M. . Relative contribution of low-density and asymptomatic infections to Plasmodium vivax transmission in the Amazon: pooled analysis of individual participant data from population-based cross-sectional surveys. The Lancet Regional Health - Americas , v. 9, p. 100169, 2022.

• PINCELLI, ANACLARA ; CARDOSO, MARLY A. ; MALTA, MAÍRA B. ; JOHANSEN, IGOR C. ; CORDER, RODRIGO M. ; NICOLETE, VANESSA C. ; SOARES, IRENE S. ; CASTRO, MARCIA C. ; FERREIRA, MARCELO U. . Low-level Plasmodium vivax exposure, maternal antibodies, and anemia in early childhood: Population-based birth cohort study in Amazonian Brazil. PLoS Neglected Tropical Diseases , v. 15, p. e0009568, 2021.

• NICOLETE, VANESSA C ; RODRIGUES, PRISCILA T ; JOHANSEN, IGOR C ; CORDER, RODRIGO M ; TONINI, JULIANA ; CARDOSO, MARLY A ; DE JESUS, JAQUELINE G ; CLARO, INGRA M ; FARIA, NUNO R ; SABINO, ESTER C ; CASTRO, MARCIA C ; FERREIRA, MARCELO U . Interacting Epidemics in Amazonian Brazil: Prior Dengue Infection Associated With Increased Coronavirus Disease 2019 (COVID-19) Risk in a Population-Based Cohort Study. Clinical Infectious Diseases , v. 73, p. 2045-2054, 2021.

• SALLA, L. C. ; RODRIGUES, P. T. ; CORDER, R. M. ; JOHANSEN, I. C. ; LADEIA-ANDRADE, S. ; FERREIRA, M. U. . Molecular evidence of sustained urban malaria transmission in Amazonian Brazil, 2014-2015. Epidemiology and Infection , v. 148, p. 1-22, 2020.

• CORDER, RODRIGO M. ; FERREIRA, MARCELO U. ; GOMES, M. GABRIELA M. . Modelling the epidemiology of residual Plasmodium vivax malaria in a heterogeneous host population: A case study in the Amazon Basin. PLOS COMPUTATIONAL BIOLOGY (ONLINE) , v. 16, p. e1007377, 2020.

• CORDER, RODRIGO M. ; DE LIMA, ANTONIO C. P. ; KHOURY, DAVID S. ; DOCKEN, STEFFEN S. ; DAVENPORT, MILES P. ; FERREIRA, MARCELO U. . Quantifying and preventing Plasmodium vivax recurrences in primaquine-untreated pregnant women: An observational and modeling study in Brazil. PLoS Neglected Tropical Diseases , v. 14, p. e0008526, 2020.

• DE OLIVEIRA, THAÍS CRIPPA ; CORDER, RODRIGO M. ; EARLY, ANGELA ; RODRIGUES, PRISCILA T. ; LADEIA-ANDRADE, SIMONE ; ALVES, JOÃO MARCELO P. ; NEAFSEY, DANIEL E. ; FERREIRA, MARCELO U. . Population genomics reveals the expansion of highly inbred Plasmodium vivax lineages in the main malaria hotspot of Brazil. PLoS Neglected Tropical Diseases , v. 14, p. e0008808, 2020.

• FERREIRA, MARCELO U. ; NOBREGA DE SOUSA, TAIS ; RANGEL, GABRIEL W. ; JOHANSEN, IGOR C. ; CORDER, RODRIGO M. ; LADEIA-ANDRADE, SIMONE ; GIL, JOSÉ PEDRO . Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions. International Journal for Parasitology-Drugs and Drug Resistance , v. 15, p. 9-24, 2020.

• LADEIA-ANDRADE, SIMONE ; MENEZES, MARIA JOSÉ ; DE SOUSA, TAÍS NÓBREGA ; SILVINO, ANA CAROLINA R. ; DE CARVALHO, JAQUES F. ; SALLA, LAÍS C. ; NERY, ODAÍLTON A. ; DE MELO, GLADSON N. P. ; CORDER, RODRIGO M. ; RODRIGUES, PRISCILA T. ; FERREIRA, MARCELO U. . Monitoring the Efficacy of Chloroquine-Primaquine Therapy for Uncomplicated Plasmodium vivax Malaria in the Main Transmission Hotspot of Brazil. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY , v. 63, p. e01965-18, 2019.

• CORDER, RODRIGO M. ; PAULA, GILBERTO A. ; PINCELLI, ANACLARA ; FERREIRA, MARCELO U. . Statistical modeling of surveillance data to identify correlates of urban malaria risk: A population-based study in the Amazon Basin. PLoS One , v. 14, p. e0220980, 2019.

• PINCELLI, ANACLARA ; LOURENÇO, BARBARA H. ; SAMPAIO-SILVA, JULIANA ; MALTA, MAÍRA B. ; CARDOSO, MARLY A. ; DE SOUZA, RODRIGO M. ; NEVES, PAULO A. R. ; CASTRO, MARCIA C. ; CORDER, RODRIGO M. ; FERREIRA, MARCELO U. . The Hidden Burden of Plasmodium vivax Malaria in Pregnancy in the Amazon: An Observational Study in Northwestern Brazil. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE , v. 99, p. 73-83, 2018.

• CORDER, R. M. ; LIMA, A. C. P. ; KHOURY, D. S. ; DOCKEN, S. S. ; DAVENPORT, M. P. ; FERREIRA, M. U. . Quantifying and preventing Plasmodium vivax recurrences in primaquine-untreated pregnant women: an observational and modeling study in Brazil. In: The 20th International Congress for Tropical Medicine and Malaria (ICTMM2020), 2022, Bangkok. Annals of the The 20th International Congress for Tropical Medicine and Malaria (ICTMM2020), 2022.

• FERREIRA, MARCELO U ; CORDER, RODRIGO M. ; JOHANSEN, IGOR C ; KATTENBERG, JOHANNA H. ; MORENO, MARTA ; ROSAS-AGUIRRE, ANGEL ; CONN, JAN E. ; GAMBOA, DIONICIA ; LLANOS-CUENTAS, ALEJANDRO ; ROSANAS-URGELL, ANNA ; VINETZ, JOSEPH M. . Quantifying the contribution of low-density and asymptomatic infections to Plasmodium vivax transmission in the Amazon. In: 18th Ecology and Evolution of Infectious Diseases Meeting, 2021, Montpellier. Annals of the 18th Ecology and Evolution of Infectious Diseases, 2021.

• FERREIRA, MARCELO U. ; CORDER, RODRIGO M. ; JOHANSEN, IGOR C. ; KATTENBERG, JOHANNA H. ; MORENO, MARTA ; ROSAS-AGUIRRE, ANGEL ; CONN, JAN E. ; GAMBOA, DIONICIA ; LLANOS-CUENTAS, ALEJANDRO ; ROSANAS-URGELL, ANNA ; VINETZ, JOSEPH M. . Quantifying the contribution of low-density and asymptomatic infections to Plasmodium vivax transmission in the Amazon. In: American Society of Tropical Medicine and Hygiene (ASTMH) 70th Annual Meeting, 2021, Virtual Meeting. Annals of the ASTMH 70th Annual Meeting, 2021.

• CORDER, R. M. ; PAULA, G. A. ; PINCELLI, A. ; FERREIRA, M. U. . Statistical modelling of surveillance data to identify correlates of urban malaria risk: a population-based study in the Amazon Basin. In: VIII Workshop on Probabilistic and Statistical Methods, 2020, São Carlos. Annals of the VIII Workshop on Probabilistic and Statistical Methods, 2020.

• CORDER, R. M. ; FERREIRA, M. U. ; GOMES, M. G. M. . Modelling the epidemiology of residual Plasmodium vivax malaria in a heterogeneous host population: a case study in the Amazon Basin. In: Workshop on Modelling of Infectious Diseases Dynamics, 2020, São Paulo. Annals of the Workshop on Modelling of Infectious Diseases Dynamics, 2020.

• CORDER, R. M. ; LIMA, A. C. P. ; KHOURY, D. ; DOCKEN, S. S. ; DAVENPORT, M. P. ; FERREIRA, M. U. . Quantifying and preventing Plasmodium vivax recurrences in primaquine-untreated pregnant women: an observational and modeling study in Brazil. In: American Society of Tropical Medicine and Hygiene (ASTMH) 69th Annual Meeting, 2020, Virtual Meeting. Annals of the ASTMH 69th Annual Meeting, 2020. v. 103.

• CORDER, R. M. ; PAULA, G. A. ; PINCELLI, A. ; FERREIRA, M. U. . Statistical modelling of surveillance data to identify correlates of urban malaria risk: a population-based study in the Amazon Basin. In: American Society of Tropical Medicine and Hygiene (ASTMH) 68th Annual Meeting, 2019, Washington DC. Annals of the ASTMH 68th Annual Meeting, 2019.

• CORDER, R. M. ; FERREIRA, M. U. ; GOMES, M. G. M. . Modelling the epidemiology of residual Plasmodium vivax malaria in a heterogeneous host population: A case study in the Amazon Basin. In: 7th International Conference on Infectious Disease Dynamics (Epidemics7), 2019, Charleston. Annals of the 7th International Conference on Infectious Disease Dynamics (Epidemics7), 2019.

• CORDER, R. M. ; FERREIRA, M. U. ; GOMES, M. G. M. . Modeling malaria transmission dynamics with heterogeneity in risk distribution. In: 16th Ecology and Evolution of Infectious Diseases, 2018, Glasgow. Annals of the 16th Ecology and Evolution of Infectious Diseases, 2018.

• CORDER, R. M. ; FERREIRA, M. U. ; GOMES, M. G. M. . Modeling malaria transmission dynamics with heterogeneity in risk distribution. In: First Malaria World Congress, 2018, Melbourne. Annals of the First Malaria World Congress, 2018.

• CORDER, R. M. ; FERREIRA, M. U. ; GOMES, M. G. M. . Mathematical modelling of malaria transmission considering heterogeneity in exposure and susceptibility of hosts. In: 6th International Conference on Plasmodium vivax Research, 2017, Manaus. Annals of the 6th International Conference on Plasmodium vivax Research, 2017.

• MONTALBAN, A. ; CORDER, R. M. . The spark of synchronization in heterogeneous networks of chaotic maps. 2024. (Apresentação de Trabalho/Seminário).

• CORDER, R. M. . Modelos matemáticos e a dinâmica de transmissão de doenças infecciosas. 2024. (Apresentação de Trabalho/Seminário).

• CORDER, R. M. . Variação individual no risco de malária: causas e consequências em populações amazônicas. 2024. (Apresentação de Trabalho/Seminário).

• CORDER, R. M. . Novas abordagens para controle de malária: do laboratório ao campo. 2024. (Apresentação de Trabalho/Seminário).

• CORDER, R. M. . Risk heterogeneity in the modeling of infectious diseases: A malaria case study in the Amazon Basin. 2024. (Apresentação de Trabalho/Seminário).

• CORDER, R. M. . Relevância da modelagem matemática na pesquisa biomédica. 2024. (Apresentação de Trabalho/Seminário).

• CORDER, R. M. . Modeling and analytics to support the transition of gene drive mosquito projects from lab to field. 2023. (Apresentação de Trabalho/Congresso).

• CORDER, R. M. ; LIMA, A. C. P. ; KHOURY, D. S. ; DOCKEN, S. S. ; DAVENPORT, M. P. ; FERREIRA, M. U. . Quantifying and preventing Plasmodium vivax recurrences in primaquine-untreated pregnant women: an observational and modeling study in Brazil. 2022. (Apresentação de Trabalho/Congresso).

• CORDER, R. M. . Modelagem Matemática de Doenças Infecciosas: Conceitos, Aplicações e Limitações. 2022. (Apresentação de Trabalho/Seminário).

• FERREIRA, MARCELO U ; CORDER, RODRIGO M. ; JOHANSEN, IGOR C ; KATTENBERG, JOHANNA H. ; MORENO, MARTA ; ROSAS-AGUIRRE, ANGEL ; CONN, JAN E. ; GAMBOA, DIONICIA ; LLANOS-CUENTAS, ALEJANDRO ; ROSANAS-URGELL, ANNA ; VINETZ, JOSEPH M. . Quantifying the contribution of low-density and asymptomatic infections to Plasmodium vivax transmission in the Amazon. 2021. (Apresentação de Trabalho/Congresso).

• CORDER, R. M. ; FERREIRA, M. U. ; GOMES, M. G. M. . Modelling the epidemiology of residual Plasmodium vivax malaria in a heterogeneous host population: a case study in the Amazon Basin. 2020. (Apresentação de Trabalho/Outra).

• CORDER, R. M. ; PAULA, G. A. ; PINCELLI, A. ; FERREIRA, M. U. . Statistical modeling of surveillance data to identify correlates of urban malaria risk: a population-based study in the Amazon Basin. 2020. (Apresentação de Trabalho/Outra).

• CORDER, R. M. ; LIMA, A. C. P. ; KHOURY, D. S. ; DOCKEN, S. S. ; DAVENPORT, M. P. ; FERREIRA, M. U. . Quantifying and preventing Plasmodium vivax recurrences in primaquine-untreated pregnant women: an observational and modeling study in Brazil. 2020. (Apresentação de Trabalho/Congresso).

• CORDER, R. M. ; FERREIRA, M. U. ; GOMES, M. G. M. . Mathematical modelling of malaria transmission considering heterogeneity in exposure and susceptibility of hosts. 2017. (Apresentação de Trabalho/Congresso).

Outras produções

Projetos de pesquisa

• 2023 - Atual

  Individual variation in malaria risk: causes and consequences in Amazonian populations, Descrição: Extensive research has examined why some people have repeated Plasmodium falciparum malaria attacks in Sub-Saharan Africa while others remain free of disease most of the time. In contrast, malaria risk heterogeneity remains little studied in regions where P. vivax is the dominant species. Are repeatedly infected people in vivax malaria settings such as the Amazon just unlucky? Here we aim to explore specific factors - including human and vector genetic polymorphism, acquired antibody-mediated immunity, and variation in parasite virulence - that can modulate the individual risk of P. vivax infection and disease in well characterized malaria-endemic Amazonian communities. We combine classical epidemiological approaches, molecular genotyping of humans, vectors and parasites, and functional antibody assays with quantitative genetics, mathematical modeling and vector biology to explore longitudinally collected data and samples from a unique population-based cohort study carried out in the main malaria transmission hotspot of Brazil. We aim to: (a) estimate the contribution of human genetics, not limited to known or suspected "malaria resistance genes", to individual malaria risk variation in Brazil; (b) to compare the differential impact of a specific human genetic polymorphism, pyruvate kinase deficiency, on P. falciparum and P. vivax malaria risk; (c) to investigate the association between naturally acquired antibodies to a key asexual blood-stage of P. vivax antigen and malaria risk; (d) to test the hypothesis that less virulent P. vivax lineages are positively selected as malaria vectors become less abundant and transmission declines; (e) to estimate the population-wide impact of specific malaria control interventions targeted at high-risk individuals; and (f) to determine how the biological heterogeneity of vectors affects the transmission dynamics of malaria considering its population structure and its preference for certain individuals (e.g., infected people). We argue that individual risk variation must be considered when designing and implementing strategies for malaria control and elimination.. , Situação: Em andamento; Natureza: Pesquisa. , Integrantes: Rodrigo Malavazi Corder - Integrante / Marcelo Urbano Ferreira - Coordenador / Sérgio Muniz Oliva - Integrante / Paulo E. M. Ribolla - Integrante / Julia M. Pavan Soler - Integrante / Taís Nóbrega de Sousa - Integrante / Ana Paula Arez - Integrante / Anna Rosanas-Urgell - Integrante / Johanna H. Kattenberg - Integrante., Financiador(es): Fundação de Amparo à Pesquisa do Estado de São Paulo - Auxílio financeiro.

• 2019 - 2022

  The clinically silent Plasmodium vivax reservoir: a systematic review and pooled analysis of individual-level data from population-based surveys across the Amazon, Descrição: International, interdisciplinary research collaboration with the aim to systematically explore the large volume of individual-level data generated by population-based surveys led by the collaborating investigators at Yale and USP in endemic settings in Brazil and Peru, combined with aggregated data generated and published by other investigators across the Amazon, to provide an accurate and up-to-date estimate of the relative contribution of asymptomatic and subpatent infections to the overall P. vivax burden and transmission in the region. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Rodrigo Malavazi Corder - Integrante / Marcelo Urbano Ferreira - Coordenador / Joseph M. Vinetz - Integrante / Igor C. Johansen - Integrante / Lauren Pischel - Integrante / Amy Bei - Integrante., Financiador(es): Universidade de São Paulo - Auxílio financeiro / Yale University - Auxílio financeiro.

• 2017 - 2021

  Modelagem matemática da transmissão da malária considerando a heterogeneidade na exposição e susceptibilidade dos hospedeiros, Descrição: O Brasil apresenta hoje a menor carga de malária em 35 anos. Após ser substancialmente reduzida nas últimas décadas, sua eliminação depende da priorização de um pequeno número de focos de transmissão onde a malária ainda persiste mesmo depois de diversas ações governamentais. Nesse sentido, estudos mais elaborados considerando novas ferramentas de análise devem ser empregados com intuito de aperfeiçoar os modelos já existentes. Modelos matemáticos, quando bem elaborados, contribuem para um entendimento dos padrões epidemiológicos e podem ser utlizados para orientar políticas públicas. Entretanto, atualmente a maior parte dos modelos desenvolvidos para malária é construída com parâmetros calibrados a partir de médias estatísticas, ou seja, considerando uma homogeneidade na susceptibilidade dos indivíduos. O presente projeto tem como objetivo o aperfeiçoamento e elaboração de modelos matemáticos em malária que levem em conta as particularidades de susceptibilidade dos indivíduos nas áreas de risco. Para isso, a partir da análise de dados previamente coletados e referentes à população local, diversas técnicas matemáticas e algoritmos computacionais serão empregados para o desenvolvimento de modelos matemáticos que considerem tais heterogeneidades e que possam descrever melhor a dinâmica da doença. Os modelos propostos poderão ser utilizados como referência para iniciativas governamentais buscando a eliminação da malária no país, e generalizados para outras doenças infecciosas. , Situação: Concluído; Natureza: Pesquisa. , Integrantes: Rodrigo Malavazi Corder - Integrante / Marcelo Urbano Ferreira - Coordenador / Maria Gabriela Miranda Gomes - Integrante., Financiador(es): Conselho Nacional de Desenvolvimento Científico e Tecnológico - Bolsa.

Prêmios