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VON BOROWSKI, RAFAEL GOMES ; ZIMMER, KARINE RIGON ; LEONARDI, BIANCA FRANCO ; TRENTIN, DANIELLE SILVA ; SILVA, RODRIGO CAMPOS ; DE BARROS, MURIEL PRIMON ; Macedo, Alexandre José ; GNOATTO, Simone Cristina Baggio ; Gosmann, Grace ; ZIMMER, Aline Rigon . Red pepper Capsicum baccatum: source of antiadhesive and antibiofilm compounds against nosocomial bacteria. INDUSTRIAL CROPS AND PRODUCTS , v. 127, p. 148-157, 2019.
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SILVA, Y. ; YENDO, Anna Carolina ; COSTA, Fernanda de ; Gosmann G ; FETT-NETO, A. G. . Foamy matters: an update on Quillaja saponins and their use as immunoadjuvants. Future Medicinal Chemistry , p. 20, 2019.
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Cibulski, Samuel ; RIVERA-PATRON, MARIANA ; SUÁREZ, NORMA ; PIREZ, MACARENA ; ROSSI, SILVINA ; YENDO, Anna Carolina ; de Costa, Fernanda ; Gosmann, Grace ; FETT-NETO, ARTHUR ; ROEHE, PAULO MICHEL ; Silveira, Fernando . Leaf saponins of Quillaja brasiliensis enhance long-term specific immune responses and promote dose-sparing effect in BVDV experimental vaccines. VACCINE , v. 36, p. 55-65, 2018.
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CARGNIN, SIMONE TASCA ; STAUDT, ANDRESSA FINKLER ; MEDEIROS, PATRÍCIA ; DE MEDEIROS SOL SOL, DANIEL ; DE AZEVEDO DOS SANTOS, ANA PAULA ; ZANCHI, FERNANDO BERTON ; Gosmann, Grace ; PUYET, ANTONIO ; GARCIA TELES, CAROLINA BIONI ; GNOATTO, SIMONE BAGGIO . Semisynthesis, cytotoxicity, antimalarial evaluation and structure-activity relationship of two series of triterpene derivatives. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , v. 28, p. 265-272, 2018.
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BRITO, FABIANO CARVALHO DE ; Gosmann, Grace ; OLIVEIRA, GUENDALINA TURCATO . Extracts of the unripe fruit of Ilex paraguariensis as a potential chemical control against the golden apple snail Pomacea canaliculata (Gastropoda,Ampullariidae). NATURAL PRODUCT RESEARCH , v. 1, p. 1-4, 2018.
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DIEDRICH, DENISE ; WILDNER, ANDREIA C. ; SILVEIRA, THAYSE F. ; SILVA, GLORIA N.S. ; SANTOS, FRANCINE DOS ; PETRY DO CANTO, VANESSA ; Gosmann, Grace ; BERGOLD, ANA MARIA ; Zimmer, Aline R. ; NETZ, PAULO A. ; GNOATTO, SIMONE C.B. . SERCA plays a crucial role in the toxicity of a betulinic acid derivative with potential antimalarial activity. CHEMICO-BIOLOGICAL INTERACTIONS , v. 287, p. 70-77, 2018.
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VENTURI, CAROLINE RITA ; BORDIGNON, SRGIO AUGUSTO DE LORETO ; ROEHE, PAULO MICHEL ; MONTANHA, JARBAS ALVES ; CIBULSKI, SAMUEL PAULO ; Gosmann, Grace . Chemical analysis and antiviral activity evaluation of Baccharis anomala . NATURAL PRODUCT RESEARCH , v. 32, p. 1-3, 2017.
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KIEKOW, CÍNTIA J. ; FIGUEIRÓ, FABRÍCIO ; DIETRICH, FABRÍCIA ; VECHIA, Luciana Dalla ; PIRES, ELISA N.S. ; JANDREY, ELISA H.F. ; GNOATTO, SIMONE C.B. ; SALBEGO, CHRISTIANNE G. ; BATTASTINI, ANA MARIA O. ; Gosmann, Grace . Quercetin derivative induces cell death in glioma cells by modulating NF-B nuclear translocation and caspase-3 activation. European Journal of Pharmaceutical Sciences , v. 84, p. 116-122, 2016.
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CIBULSKI, SAMUEL PAULO ; Silveira, Fernando ; MOURGLIA-ETTLIN, GUSTAVO ; TEIXEIRA, THAIS FUMACO ; DOS SANTOS, HELTON FERNANDES ; YENDO, Anna Carolina ; de Costa, Fernanda ; FETT-NETO, ARTHUR GERMANO ; Gosmann, Grace ; ROEHE, PAULO MICHEL . Quillaja brasiliensis saponins induce robust humoral and cellular responses in a bovine viral diarrhea virus vaccine in mice. Comparative Immunology, Microbiology and Infectious Diseases , v. 45, p. 1-8, 2016.
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YENDO, ANNA CAROLINA A. ; de Costa, Fernanda ; CIBULSKI, SAMUEL P. ; TEIXEIRA, THAIS F. ; COLLING, LUANA C. ; MASTROGIOVANNI, MAURICIO ; SOULÉ, SILVIA ; Roehe, Paulo M. ; Gosmann, Grace ; FERREIRA, FERNANDO A. ; Fett-Neto, Arthur G. . A rabies vaccine adjuvanted with saponins from leaves of the soap tree (Quillaja brasiliensis) induces specific immune responses and protects against lethal challenge. Vaccine (Guildford) , v. 34, p. 2305-2311, 2016.
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Allemand, A ; Leonardi B ; ZIMMER, Aline R ; ROMAO, P. R. T. ; Gosmann, G. . Red Pepper ( ) Extracts Present Anti-Inflammatory Effects and Inhibit the Production of TNF- and NO. Journal of Medicinal Food , v. 19, p. 759-767, 2016.
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DA SILVA, GLORIA NS ; TRINDADE, FRANCES TT ; DOS SANTOS, FRANCINE ; Gosmann, Grace ; E SILVA, ALEXANDRE A ; GNOATTO, SIMONE CB . Larvicidal activity of natural and modified triterpenoids against (Diptera: Culicidae). Pest Management Science (Print) , v. 72, p. 1883-1887, 2016.
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SILVA, GLORIA N. S. ; SCHUCK, DESIRÉE C. ; CRUZ, LAURA N. ; MORAES, MIRIAM S. ; NAKABASHI, MYNA ; Gosmann, Grace ; GARCIA, CÉLIA R. S. ; Gnoatto, Simone C. B. . Investigation of antimalarial activity, cytotoxicity and action mechanism of piperazine derivatives of betulinic acid. TM & IH. Tropical Medicine and International Health (Print) , v. 20, p. 29-39, 2015.
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CASANOVA, BRUNA ; MUNIZ, MAURO ; DE OLIVEIRA, THAYSE ; DE OLIVEIRA, LUÍS ; MACHADO, MICHEL ; FUENTEFRIA, ALEXANDRE ; Gosmann, Grace ; Gnoatto, Simone . Synthesis and Biological Evaluation of Hydrazone Derivatives as Antifungal Agents. Molecules (Basel. Online) , v. 20, p. 9229-9241, 2015.
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Yendo, A.C.A. ; de Costa, F. ; FLECK, J.D. ; Gosmann, G. ; FETT-NETO, A.G. . Irradiance-based treatments of Quillaja brasiliensis leaves (A. St.-Hil. & Tul.) Mart. as means to improve immunoadjuvant saponin yield. Industrial Crops and Products (Print) , v. 74, p. 228-233, 2015.
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Silva G N S ; REZENDE, L. C. D. ; EMERY, F. S. ; Gosmann, Grace ; GNOATTO, Simone Cristina Baggio . Natural and Semi synthetic Antimalarial Compounds: Emphasis on the Terpene Class. Mini-Reviews in Medical Chemistry , v. 15, p. 809-836, 2015.
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LEAO, R. A. C. ; LOPES, R. O. ; BEZERRA, M. A. M. ; MUNIZ, M. N. ; CASANOVA, B. B. ; GNOATTO, Simone Cristina Baggio ; Gosmann, Grace ; KOCSIS, L. ; SOUZA, R. O. M. A. ; MIRANDA, L. S. M. . Studies on the Continuous-Flow Synthesis of Nonpeptidal bis-Tetrahydrofuran Moiety of Darunavir. J FLOW CHEM , v. 5, p. 216-219, 2015.
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YENDO, Anna Carolina ; COSTA, Fernanda de ; COSTA, C. T. ; COLLING, L. C. ; Gosmann, Grace ; FETT-NETO, A. G. . Biosynthesis of Plant Triterpenoid Saponins: Genes, Enzymes and their Regulation. Mini-Reviews in Organic Chemistry , v. 11, p. 292-306, 2014.
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Duarte M O ; Lunardelli S ; Kiekow C J ; STEIN, A. C. ; MULLER, L. ; Stolz E D ; RATES, Stela M K ; GOSMANN, G. . Phloroglucinol derivatives present an antidepressant-like effect in the mice tail suspension test (TST). Natural Product Communications , v. 9, p. 671-674, 2014.
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Santos, Regineide Xavier ; Oliveira D A ; Sodré G A ; Gosmann, G. ; Brendel M ; PUNGARTNIK C . Antimicrobial activity of fermented Theobroma cacao pod husk extract. Genetics and Molecular Research , v. 13, p. 7725-7735, 2014.
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INNOCENTE, ADRINE ; CASANOVA, BRUNA B. ; KLEIN, FERNANDA ; LANA, ALINE D. ; PEREIRA, DARIANE ; MUNIZ, MAURO N. ; SONNET, Pascal ; Gosmann, Grace ; FUENTEFRIA, ALEXANDRE M. ; Gnoatto, Simone C. B. . Synthesis of Isosteric Triterpenoid Derivatives and Antifungal Activity. Chemical Biology & Drug Design (Print) , v. 83, p. 344-349, 2014.
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OLIVEIRA, Simone Quintana de ; KAPPEL, Virgínia D ; PIRES, Viviane S ; LENCINA, Claiton Leoneti ; SONNET, Pascal ; MOREIRA, José Cláudio F ; Gosmann, G. . Antioxidant Properties of Phenolic Compounds from Baccharis articulata and B. usterii. Natural Product Communications , v. 9, p. 941-942, 2014.
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Innocente, A M ; Vieira P de B ; FRASSON, A. P. ; CASANOVA, B. B. ; Gossmann, Grace ; GNOATTO, Simone Cristina Baggio ; Tasca, Tiana . Anti-Trichomonas vaginalis activity from triterpenoid derivatives. Parasitology Research (1987. Print) , v. 2, p. 344, 2014.
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de Costa, Fernanda ; YENDO, ANNA CAROLINA A. ; CIBULSKI, SAMUEL P. ; Fleck, Juliane D. ; Roehe, Paulo M. ; SPILKI, FERNANDO R. ; Gosmann, Grace ; Fett-Neto, Arthur G. . Alternative Inactivated Poliovirus Vaccines Adjuvanted with Quillaja brasiliensis or Quil-A Saponins Are Equally Effective in Inducing Specific Immune Responses. Plos One , v. 9, p. e105374, 2014.
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BRAGA, ANDRESSA ; CRISTINA STEIN, ANA ; DISCHKALN STOLZ, EVELINE ; DALLEGRAVE, ELIANE ; BUFFON, ANDRÉIA ; DO REGO, JEAN-CLAUDE ; Gosmann, Grace ; FIALHO VIANA, ALICE ; KUZE RATES, STELA MARIS . Repeated administration of an aqueous spray-dried extract of the leaves of Passiflora alata Curtis (Passifloraceae) inhibits body weight gain without altering mice behavior. Journal of Ethnopharmacology , v. 145, p. 59-66, 2013.
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de Costa, Fernanda ; YENDO, ANNA CAROLINA ALVES ; FLECK, JULIANE DEISE ; Gosmann, Grace ; FETT-NETO, ARTHUR GERMANO . Accumulation of a bioactive triterpene saponin fraction of Quillaja brasiliensis leaves is associated with abiotic and biotic stresses. Plant Physiology and Biochemistry (Paris) , v. 66, p. 56-62, 2013.
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DA SILVA, GLORIA NS ; MARIA, NICOLE RG ; SCHUCK, DESIRÉE C ; CRUZ, LAURA N ; DE MORAES, MÍRIAM S ; NAKABASHI, MYNA ; GRAEBIN, CEDRIC ; Gosmann, Grace ; GARCIA, CÉLIA RS ; GNOATTO, SIMONE CB . Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action. Malaria Journal (Online) , v. 12, p. 89-95, 2013.
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DE OLIVEIRA, CRISTIANE ; COMUNELLO, LUCIMARA ; MACIEL, ÉRICA ; GIUBEL, SCHERON ; BRUNO, ALESSANDRA ; CHIELA, EDUARDO ; LENZ, GUIDO ; Gnoatto, Simone ; BUFFON, ANDRÉIA ; Gosmann, Grace . The Inhibitory Effects of Phenolic and Terpenoid Compounds from Baccharis trimera in Siha Cells: Differences in Their Activity and Mechanism of Action. Molecules (Basel. Online) , v. 18, p. 11022-11032, 2013.
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HASSUM, I. C. ; Venturi, C R ; Gosmann, Grace ; DEIRO, A. M. G. . Ação dos extratos de quatro plantas sobre larvas infectantes de nematódeos gastrintestinais de ovinos.. Revista Cubana de Plantas Medicinales , v. 18, p. 278-287, 2013.
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DE PAULA, FERNANDO T. ; FRAUCHES, PETRINA Q. ; PEDEBOS, CONRADO ; BERGER, MARKUS ; Gnoatto, Simone C. B. ; Gossmann, Grace ; VERLI, HUGO ; GUIMARÃES, JORGE A. ; GRAEBIN, CEDRIC S. . Improving the thrombin inhibitory activity of Glycyrrhizin, a triterpenic saponin, through a molecular simplification of the carbohydrate moiety. Chemical Biology & Drug Design (Print) , v. 82, p. 756-760, 2013.
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VECHIA, Luciana Dalla ; Kiekow C J ; LEAL, I. C. R. ; SANTOS, K. R. N. ; GNOATTO, Simone Cristina Baggio ; Verli H ; SOUZA, R. O. M. A. ; Gosmann, Grace . Synthesis of Oxygenated Chalcones with Anti-Staphylococcal Activity. Letters in Drug Design & Discovery , v. 11, p. 525-530, 2013.
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Verza S G ; Resende P E ; Kaiser S ; Quirici L ; Teixeira H F ; Gosmann, Grace ; Ferreira F ; GONZALEZ-ORTEGA, G. . Micellar aggregates of saponins from Chenopodium quinoa: characterization by dynamic light scattering and transmission electron microscopy. Die Pharmazie (Berlin) , v. 67, p. 288-292, 2012.
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VECHIA, Luciana Dalla ; Dassonville-Klimpt A ; Grellier P ; SONNET, Pascal ; Gosmann, G. ; Gnoatto, Simone C. B. . The Beckmann Rearrangement Applied to Ursolic Acid with Antimalarial Activity in Medicinal Chemistry Studies. Letters in Organic Chemistry , v. 9, p. 92-95, 2012.
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ZIMMER, Aline Rigon ; Leonardi, Bianca ; Miron, Diogo ; Schapoval, Elfrides ; Oliveira, Jarbas Rodrigues de ; Gosmann, Grace . Antioxidant and anti-inflammatory properties of Capsicum baccatum: From traditional use to scientific approach. Journal of Ethnopharmacology , v. 139, p. 228-233, 2012.
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Rocha, Tábitha Dahmer ; Brum Vieira, Patrícia ; GNOATTO, Simone Cristina Baggio ; Tasca, Tiana ; Gosmann, Grace . Anti-Trichomonas vaginalis activity of saponins from Quillaja, Passiflora, and Ilex species. Parasitology Research (1987. Print) , p. 2551-2556, 2012.
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de Oliveira, Cristiane B. ; Comunello, Lucimara N. ; Lunardelli, Adroaldo ; Amaral, Robson H. ; Pires, Melissa G. S. ; da Silva, Gabriela Lucas ; Manfredini, Vanusa ; Vargas, Carmen Regla ; Gnoatto, Simone C. B. ; de Oliveira, Jarbas R. ; Gosmann, Grace . Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities. Molecules (Basel. Online) , v. 17, p. 1113-1123, 2012.
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Saito, Samuel ; Silva, Givaldo ; Santos, Regineide Xavier ; Gosmann, Grace ; Pungartnik, Cristina ; Brendel, Martin . Astragalin from Cassia alata Induces DNA Adducts in Vitro and Repairable DNA Damage in the Yeast Saccharomyces cerevisiae. International Journal of Molecular Sciences (Online) , v. 13, p. 2846-2862, 2012.
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Verza, Simone G. ; Silveira, Fernando ; Cibulski, Samuel ; Kaiser, Samuel ; Ferreira, Fernando ; Gosmann, Grace ; Roehe, Paulo M. ; Ortega, George G. . Immunoadjuvant Activity, Toxicity Assays, and Determination by UPLC/Q-TOF-MS of Triterpenic Saponins from Chenopodium quinoa Seeds. Journal of Agricultural and Food Chemistry , v. 60, p. 3113-3118, 2012.
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Gosmann, Grace ; Barlette, Adriana Gregory ; Dhamer, Tabitha ; ArÃari, DemÃtrius P. ; Santos, Juliana Carvalho ; Camargo, Eloà Ramalho ; Acedo, Simone ; Gambero, Alessandra ; GNOATTO, Simone Cristina Baggio ; Ribeiro, Marcelo Lima . Phenolic Compounds from Matà (Ilex paraguariensis) Inhibit Adipogenesis in 3T3-L1 Preadipocytes. Plant Foods for Human Nutrition (Dordrecht) , p. 156-161, 2012.
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Rocha T D ; BERGER, M. ; Barlette A G ; Reck Jr J ; Segalin J ; Verza S ; GONZALEZ-ORTEGA, G. ; S. B. Gnoatto ; Guimarães J A ; Verli H ; Gosmann, Grace . Antithrombotic Effect of Chikusetsusaponin IVa Isolated from (Maté). Journal of Medicinal Food , v. 15, p. 1073-1080, 2012.
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Innocente, A M ; Silva G N S ; Cruz L N ; MORAES, M. S. ; NAKABASHI, M. ; SONNET, Pascal ; Gosmann, G. ; Garcia C R S ; GNOATTO, Simone Cristina Baggio . Synthesis and Antiplasmodial Activity of Betulinic Acid and Ursolic Acid Analogues. Molecules (Basel. Online) , v. 17, p. 12003-12014, 2012.
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Fleck, Juliane D. ; de Costa, Fernanda ; Yendo, Anna C.A. ; Segalin, Jéferson ; Dalla Costa, Teresa C.T. ; Fett-Neto, Arthur G. ; Gosmann, Grace . Determination of new immunoadjuvant saponin named QB-90, and analysis of its organ-specific distribution in Quillaja brasiliensis by HPLC. Natural Product Research (Print) , v. 27, p. 1-910, 2012.
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Saito, Samuel Takashi ; Trentin, Danielle da Silva ; Macedo, Alexandre José ; Pungartnik, Cristina ; GOSMANN, G. ; Silveira, Jaqueline de Deos ; GUECHEVA, T. N. ; Henriques, João Antonio Pêgas ; Brendel, Martin . Bioguided Fractionation Shows Cassia alata Extract to Inhibit Staphylococcus epidermidis and Pseudomonas aeruginosa Growth and Biofilm Formation. Evidence-Based Complementary and Alternative Medicine (Print) , v. 2012, p. 1-13, 2012.
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ZIMMER, Aline Rigon ; Leonardi, Bianca ; ZIMMER, EDUARDO RIGON ; KALININE, EDUARDO ; DE SOUZA, DIOGO ONOFRE ; PORTELA, LUIS VALMOR ; Gosmann, Grace . Long-Term Oral Administration of Capsicum baccatum Extracts Does Not Alter Behavioral, Hematological, and Metabolic Parameters in CF1 Mice. Evidence-based Complementary and Alternative Medicine , v. 183, p. 09-12, 2012.
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Lencina, Claiton L. ; Cardoso, Mariana C. de ; ZANCANARO, Ivomar ; Pires, Viviane S. ; SONNET, Pascal ; GUILLAUME, Dominique ; Schenkel, Eloir P. ; Gosmann, Grace . Triterpenes and new saponins from Ilex chamaedryfolia: chemotaxonomic tool to ilex species differentiation. Química Nova (Impresso) , v. 34, p. 222-225, 2011.
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Guillon, Jean ; Mouray, Elisabeth ; Moreau, Stéphane ; Mullié, Catherine ; Forfar, Isabelle ; Desplat, Vanessa ; Belisle-Fabre, Solene ; Pinaud, Noël ; Ravanello, François ; Le-Naour, Augustin ; Léger, Jean-Michel ; Gosmann, Grace ; JARRY, Christian ; Déléris, Gérard ; SONNET, Pascal ; Grellier, Philippe . New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: Synthesis, and in vitro antimalarial activity Part II. European Journal of Medicinal Chemistry , v. 46, p. 2310-2326, 2011.
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Gosmann, G. ; PROVENSI, G. ; Comunello L N ; RATES, S. M. K. . Composição química e aspectos farmacológicos de espécies de Passiflora L. (Passifloraceae). Revista Brasileira de Biociências (Online) , v. 9, p. 88-99, 2011.
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de Costa, F. ; C.A. Yendo, A. ; D. Fleck, J. ; Gosmann, G. ; G. Fett-Neto, A. . Immunoadjuvant and Anti-Inflammatory Plant Saponins: Characteristics and Biotechnological Approaches Towards Sustainable Production. Mini-Reviews in Medical Chemistry , v. 11, p. 857-880, 2011.
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Silveira, F. ; Rossi, S. ; Fernández, C. ; Gosmann, G. ; Schenkel, E. ; Ferreira, F. . Alum-type Adjuvant Effect of Non-haemolytic Saponins Purified from Ilex and Passiflora spp.. PTR. Phytotherapy Research , v. 25, p. 1783-1788, 2011.
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Silveira, F. ; Cibulski, S.P. ; Varela, A.P. ; Marqués, J.M. ; Chabalgoity, A. ; de Costa, F. ; Yendo, A.C.A. ; Gosmann, G. ; Roehe, P.M. ; Fernández, C. ; Ferreira, F. . Quillaja brasiliensis saponins are less toxic than Quil A and have similar properties when used as an adjuvant for a viral antigen preparation. Vaccine (Guildford) , v. 29, p. 9177-9182, 2011.
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Boeira J M ; Betti A ; PROVENSI, G. ; Lacerda L A ; Barbosa P R ; Gonzalez F H D ; Driemeier D ; Pedroso A P ; Correa A M R ; DALLALBA, M. P. ; Gosmann, Grace ; RATES, Stela M K . Toxicity and genotoxicity evaluation of Passiflora alata Curtis (Passifloraceae). Journal of Ethnopharmacology , v. 128, p. 526-532, 2010.
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Yendo, Anna C. A. ; Costa, Fernanda ; Gosmann, Grace ; Fett-Neto, Arthur G. . Production of Plant Bioactive Triterpenoid Saponins: Elicitation Strategies and Target Genes to Improve Yields. Molecular Biotechnology , v. 46, p. 94-104, 2010.
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Mullié, Catherine ; Jonet, Alexia ; Dassonville-Klimpt, Alexandra ; Gosmann, Grace ; SONNET, Pascal . Inhibitory effect of ursolic acid derivatives on hydrogen peroxide- and glutathione-mediated degradation of hemin: A possible additional mechanism of action for antimalarial activity. Experimental Parasitology , v. 125, p. 202-207, 2010.
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HOLZSCHUH, M H ; GOSMANN, G. ; Schneider, Paulo H. ; SCHAPOVAL, E. E. S ; BASSANI, Valquíria L . Identification and stability of a new bichalcone in Achyrocline satureioides spray dried powder. Die Pharmazie (Berlin) , v. 65, p. 650-656, 2010.
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Staub I ; Flores L ; Gosmann, Grace ; Pohlmann A ; FROEHLICH, P. E. ; SCHAPOVAL, E. E. S. ; BERGOLD, A. M. . PHOTOSTABILITY STUDIES OF KETOCONAZOLE: ISOLATION AND STRUCTURAL ELUCIDATION OF THE MAIN PHOTODEGRADATION PRODUCTS. Acta Farmaceutica Bonaerense , v. 29, p. 1100-1106, 2010.
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Dalla Vechia, Luciana ; Gnoatto, Simone C. B. ; Gosmann, Grace . Derivados oleananos e ursanos e sua importância na descoberta de novos fármacos com atividade antitumoral, anti-inflamatória e antioxidante. Química Nova , v. 32, p. 1245-1252, 2009.
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Adams, Andréa I. H. ; Gosmann, Grace ; Schneider, Paulo H. ; Bergold, Ana M. . LC Stability Studies of Voriconazole and Structural Elucidation of Its Major Degradation Product. Chromatographia (Wiesbaden) , v. 69, p. 115-122, 2009.
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FLECK, J. D. ; COSTA, Fernanda de ; YENDO, Anna Carolina ; SCHWAMBACH, J. ; Gosmann, Grace ; FETT-NETO, A. G. . Immunoadjuvant saponin production in seedlings and micropropagated plants of Quillaja brasiliensis. In Vitro Cellular & Developmental Biology. Plant , v. 45, p. 715-720, 2009.
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Paul, Elisiane Lozza ; Lunardelli, Adroaldo ; Caberlon, Eduardo ; Oliveira, Cristiane Bernardes ; Santos, Roberto Christ Vianna ; Biolchi, Vanderlei ; Bastos, Carolina Maria Alves ; Moreira, Karla Barbosa ; Nunes, Fernanda Bordignon ; Gosmann, Grace ; Oliveira, Jarbas Rodrigues . Anti-inflammatory and Immunomodulatory Effects of Baccharis trimera Aqueous Extract on Induced Pleurisy in Rats and Lymphoproliferation In Vitro. Inflammation , v. 32, p. 419-425, 2009.
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SAITO, Samuel Takashi ; Gosmann, G. ; PUNGARTNIK C ; Brendel M . Green Tea Extract-Patents and Diversity of Uses. Recent Patents on Food, Nutrition & Agriculture , v. 1, p. 203-215, 2009.
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FENNER, Raquel ; Zimmer, Aline R. ; Neves, Gilda ; Kliemann, Michele ; Gosmann, Grace ; Rates, Stela M. K. . Hypnotic effect of ecdysterone isolated from Pfaffia glomerata (Spreng.) Pedersen. Revista Brasileira de Farmacognosia , v. 18, p. 170-176, 2008.
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GNOATTO, Simone Cristina Baggio ; Susplugas S ; VECHIA, Luciana Dalla ; Ferreira T B ; Dassonville-Klimpt A ; Zimmer K R ; Demailly C ; Da Nascimento S ; Guillon J ; Grellier P ; Verli H ; GOSMANN, G. ; SONNET, Pascal . Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents. Bioorganic & Medicinal Chemistry , v. 16, p. 771-782, 2008.
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GNOATTO, S C B ; Dassonville-Klimpt A ; NASCIMENTO, S. da ; Galera P ; Boumediene K ; GOSMANN, G. ; SONNET, Pascal ; Moslemi S . Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition. European Journal of Medicinal Chemistry , v. 43, p. 1865-1877, 2008.
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Gnoatto, Simone ; VECHIA, Luciana Dalla ; Lencina, Claiton ; Dassonville-Klimpt, Alexandra ; Da Nascimento, Sophie ; Mossalayi, Djavad ; Guillon, Jean ; Gosmann, Grace ; SONNET, Pascal . Synthesis and preliminary evaluation of new ursolic and oleanolic acids derivatives as antileishmanial agents. Journal of Enzyme Inhibition and Medicinal Chemistry , v. 23, p. 604-610, 2008.
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PROVENSI, G. ; Noel, F ; Lopes, D VS ; FENNER, Raquel ; BETI, Andressa H ; COSTA, Fernanda de ; MORAIS, Everton ; GOSMANN, G. ; RATES, S. M. K. . Participation of GABA-benzodiazepine receptor complex in the anxiolytic effect of Passiflora alata Curtis (Passifloraceae). Acta Farmaceutica Bonaerense , v. 27, p. 845-851, 2008.
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Gnoatto, Simone ; Guillon, Jean ; SILVA PIRES, Viviane ; Dassonville-Klimpt, Alexandra ; Da Nascimento, Sophie ; MASSIP, Stéphane ; JARRY, Christian ; Gosmann, Grace ; SONNET, Pascal . Crystal Structure of 3-O-Acetyloleanolic Acid. Analytical Sciences , v. 24, p. x239-x240, 2008.
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PAVEI, C. ; guzatto p ; PETROVICK, P. R. ; GOSMANN, G. ; GONZALEZ-ORTEGA, G. . Development and Validation of an HPLC Method for the Characterization and Assay of the Saponins from Ilex paraguariensis A. St.-Hil (Mate) Fruits. Journal of Liquid Chromatography & Related Technologies , v. 30, p. 87-95, 2007.
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VARGAS, A ; GEREMIAS, D S ; PROVENSI, Gustavo ; FORNARI, Paula Eidt ; REGINATTO, Flavio H ; GOSMANN, G. ; SCHENKEL, Eloir Paulo ; FRODE, T S . Passiflora alata and Passiflora edulis spray-dried aqueous extracts inhibit inflammation in mouse model of pleurisy. Fitoterapia , v. 78, p. 112-119, 2007.
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SAITO, Samuel Takashi ; FROEHLICH, P. E. ; BERGOLD, A. M. ; GOSMANN, G. . Full validation of a simple method for determination of catechins and caffeine in Brazilian green tea (Camellia sinensis var. assamica) using HPLC. Chromatographia (Wiesbaden) , v. 65, p. 607-610, 2007.
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SAITO, Samuel Takashi ; GOSMANN, G. ; Saffi J ; Presser M ; Richter M F ; BERGOLD, A. M. . Characterization of the constituents and antioxidant activity of Brazilian green tea (Camellia sinensis var. assamica IAC-259 cultivar) extracts. Journal of Agricultural and Food Chemistry , v. 55, p. 9409-9414, 2007.
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ZIMMER, Aline R ; BRUXEL, Fernanda ; BASSANI, Valquíria L ; GOSMANN, G. . HPLC method for the determination of ecdysterone in extractive solution from Pfaffia glomerata. Journal of Pharmaceutical and Biomedical Analysis , v. 40, n.2, p. 450-453, 2006.
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Barp, E. A. ; Soares, G. L. G. ; GOSMANN, G. ; MACHADO, A. M. ; Vecchi, C. ; Moreira, G. R. P. . Phenotypic plasticity in Passiflora suberosa L.(Passifloraceae): induction and reversion of two morphs by variation in light intensity. Brazilian Journal of Biology , São Carlos, v. 66, p. 533, 2006.
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REGINATTO, F H ; DEPARIS, F. ; PETRY, R. D. ; QUEVEDO, J. ; GONZALEZ-ORTEGA, G. ; GOSMANN, G. ; SCHENKEL, E. P. . Evaluation of anxiolytic activity of spray dried powders of two south Brazilian Passiflora species. Phytotherapy Research , v. 20, n.5, p. 348-351, 2006.
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FLECK, J. D. ; KAUFFMANN, C. ; SPILKI, F. ; LENCINA, Claiton Leoneti ; ROEHE, P. M. ; GOSMANN, G. . Adjuvant activity of Quillaja brasiliensis saponins on the immune responses to bovine herpesvirus type 1 in mice. Vaccine (Guildford) , v. 24, p. 7129-7134, 2006.
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OLIVEIRA, S. Q. DE ; BARBON, Gisele ; BORDIGNON, S. ; GOSMANN, G. . Differentiation of South Brazilian Baccharis species by TLC. Journal of Liquid Chromatography & Related Technologies , v. 29, p. 2603-2609, 2006.
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BIRK, C D ; PROVENSI, Gustavo ; REGINATTO, F H ; SCHENKEL, Eloir P ; GOSMANN, G. . TLC fingerprint of flavonoids and saponins from Passiflora species. Journal of Liquid Chromatography & Related Technologies , Salisbury, v. 28, p. 2285-2291, 2005.
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OLIVEIRA, Simone Quintana de ; TRENTIN, Vania H ; KAPPEL, Virgínia D ; BARELLI, Cristiane ; GOSMANN, G. ; REGINATTO, Flávio H . Screening of antibacterial activity of South Brazilian Baccharis species. Pharmaceutical Biology , v. 43, n.5, p. 434-438, 2005.
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KAUFFMANN, C. ; MACHADO, A M ; FLECK, J. D. ; PROVENSI, Gustavo ; PIRES, Viviane S ; GUILLAUME, Dominique ; SONNET, Pascal ; REGINATTO, F H ; SCHENKEL, Eloir P ; GOSMANN, G. . Constituents from leaves of Quillaja brasiliensis. Natural Product Letters , v. 18, n.2, p. 153-157, 2004.
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REGINATTO, Flávio H ; GOSMANN, G. ; SCHRIPSEMA, J. ; SCHENKEL, E. P. . Assay of quadranguloside, the major saponin of leaves of Passiflora alata, by HPLC-UV. Phytochemical Analysis , v. 15, n.3, p. 195-197, 2004.
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OLIVEIRA, Simone Quintana de ; DAL-PIZZOL, Felipe ; MOREIRA, José Cláudio F ; SCHENKEL, Eloir P ; GOSMANN, G. . Antioxidant activity of baccharis spicata, Baccharis trimera and Baccharis usterii. Acta Farmaceutica Bonaerense , La Plata, v. 23, n.3, p. 365-368, 2004.
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Taketa, Alexandre T. C. ; Gnoatto, Simone C. B. ; Gosmann, Grace ; Pires, Viviane S. ; Schenkel, Eloir P. ; GUILLAUME, Dominique . Triterpenoids from Brazilian. Journal of Natural Products , v. 67, p. 1697-1700, 2004.
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OLIVEIRA, Simone Quintana de ; DAL-PIZZOL, Felipe ; GOSMANN, G. ; GUILLAUME, D. ; MOREIRA, José Cláudio F ; SCHENKEL, E. P. . Antioxidant activity of Baccharis articulata extracts: Isolation of a new compound with antioxidant activity. Free Radical Research , Oxford, v. 37, n.5, p. 555-559, 2003.
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Gosmann, Grace ; GATTUSO, Susana ; GATTUSO, Martha ; FENNER, Raquel ; PACHECO, Elyara Fiorin ; Ferraz, Alexandre ; Savi, Luciane Anita ; Barardi, Célia Regina Monte ; Simões, Cláudia Maria Oliveira ; Sortino, Maximiliano ; Zacchino, Susana ; Gnerre, Carmela ; Testa, Bernard ; Rates, Stela Maris Kuze . Botanical (morphological, micrographic), chemical and pharmacological characteristics of Pfaffia species (Amaranthaceae) native to South Brazil. RBCF. Revista Brasileira de Ciências Farmacêuticas , São Paulo, v. 39, n.2, p. 141-147, 2003.
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DEPARIS, F. ; PETRY, R. D. ; REGINATTO, Flávio H ; GOSMANN, G. ; QUEVEDO, J. ; SALGUEIRO, J. ; KAPCZINSKI, F. ; GONZALEZ-ORTEGA, G. ; SCHENKEL, Eloir P . Pharmacochemical study of aqueous extracts of Passiflora alata Dryander and Passiflora edulis Sims. Acta Farmaceutica Bonaerense , La Plata, v. 21, n.1, p. 5-8, 2002.
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Pires, Viviane S. ; Taketa, Alexandre T. C. ; Gosmann, Grace ; Schenkel, Eloir P. . Saponins and Sapogenins from Brachiaria decumbens Stapf. Journal of the Brazilian Chemical Society , São Paulo, v. 13, n.2, p. 422, 2002.
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PIRES, Viviane S ; GOSMANN, G. ; GUILLAUME, D. ; SCHENKEL, E. P. . Triterpenes and saponins from Ilex psammophila. Natural Product Letters , Hampshire, v. 16, n.6, p. 401-406, 2002.
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RATES, S. M. K. ; GOSMANN, G. . Gênero Pfaffia: Aspectos químicos, farmacológicos e implicações para o seu emprego terapêutico. Revista Brasileira de Farmacognosia (Impresso) , Maringá, v. 12, n.2, p. 85-93, 2002.
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PETRY, R. D. ; REGINATTO, Flávio H ; DEPARIS, F. ; GOSMANN, G. ; SALGUEIRO, J. ; QUEVEDO, J. ; KAPCZINSKI, F. ; GONZALEZ-ORTEGA, G. ; SCHENKEL, E. P. . Comparative pharmacological study of hydroethanol extracts of Passiflora alata and Passiflora edulis leaves. Phytotherapy Research , Londres, v. 15, n.2, p. 162-164, 2001.
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ATHAYDE, M. L. ; SCHENKEL, E. P. ; GNOATTO, S B ; GOSMANN, G. ; GIBERTI, G. C. ; GUILLAUME, D. . Triterpenes and saponins from Ilex argentina leaves. Acta Farmaceutica Bonaerense , La Plata, v. 20, n.1, p. 13-16, 2001.
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Reginatto, Flávio H. ; Kauffmann, Carla ; Schripsema, Jan ; GUILLAUME, Dominique ; Gosmann, Grace ; Schenkel, Eloir P. . Steroidal and triterpenoidal glucosides from Passiflora alata. Journal of the Brazilian Chemical Society , São Paulo, v. 12, n.1, p. 32, 2001.
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C Lencina ; PIRES, Viviane S ; GOSMANN, G. ; TAKETA, A. T. C. ; SCHENKEL, E. P. . Tilirosídeo em Croton gnaphalii Baill. Revista Brasileira de Farmacognosia (Impresso) , Maringá, PR, v. 11, n.2, p. 89-93, 2001.
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TAKETA, A. T. C. ; SCHMITTMANNSCHLAGER, T. ; GUILLAUME, D. ; GOSMANN, G. ; SCHENKEL, E. P. . Triterpenoid glycosides and a triterpene from Ilex brevicuspis. Phytochemistry , v. 53, n.8, p. 901-904, 2000.
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ATHAYDE, M. L. ; SCHENKEL, Eloir Paulo ; GOSMANN, G. ; GUILLAUME, Dominique . Triterpenoids from the leaves of Ilex theezans Martius ex Reiss.. Acta Farmaceutica Bonaerense , La Plata, v. 18, p. 49-52, 1999.
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Reginatto, F.H. ; Athayde, M.L. ; Gosmann, G. ; Schenkel, E.P. . Methylxanthines accumulation in Ilex species - caffeine and theobromine in erva-mate (Ilex paraguariensis) and other Ilex species. Journal of the Brazilian Chemical Society (Impresso) , São Paulo, v. 10, n.6, p. 443-446, 1999.
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PIRES, V. ; GUILLAUME, Dominique ; GOSMANN, G. ; SCHENKEL, Eloir Paulo . Saponins from Ilex dumosa, an erva-maté (Ilex paraguariensis) adulterating plant. Journal of Agricultural and Food Chemistry , v. 45, p. 1027-1031, 1997.
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SCHENKEL, Eloir Paulo ; GOSMANN, G. ; MONTANHA, J. A. ; HEIZMANN, B. M. ; ATHAYDE, M. L. ; TAKETA, Alexandre T C ; PIRES, Viviane S ; GUILLAUME, Dominique . Saponins from mate (Ilex paraguariensis) and other South American Ilex species: ten years research on Ilex saponins.. Ciência e Cultura (SBPC) , São Paulo, v. 49, p. 359-363, 1997.
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KRAEMER, K. H. ; TAKETA, Alexandre T C ; SCHENKEL, Eloir Paulo ; GOSMANN, G. ; GUILLAUME, Dominique . Matesaponin 5, a highly polar saponin from Ilex paraguariensis. Phytochemistry , Oxford, v. 42, n.4, p. 1119-1122, 1996.
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GOSMANN, G. ; GUILLAUME, Dominique ; HUSSON, H. . Asymmetric synthesis XLI. Totally stereoselective synthesis of 1,3-disubstituted tetrahydroisoquinolines via the CN (R,S) method.. Tetrahedron Letters , v. 37, p. 4369-4372, 1996.
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GOSMANN, G. ; GUILLAUME, Dominique ; TAKETA, Alexandre T C ; SCHENKEL, Eloir Paulo . Triterpenoid saponins from Ilex paraguariensis. Journal of Natural Products , Chicago, v. 58, n.3, p. 438-441, 1995.
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POSER, G. L. V. ; GOSMANN, G. ; CAMARGO, S. A. . Atividade antimicrobiana do óleo volátil dos frutos de Zanthoxylum rhoifolium. Revista Brasileira de Farmácia , Rio de Janeiro, v. 72, n.2, p. 29-30, 1991.
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COPAT, E. ; GOSMANN, G. . Saponinas de Quillaja brasiliensis. Acta Biologica Leopoldensia , São Leopoldo, v. 12, n.supl. esp., p. 65-72, 1990.
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POSER, G. L. V. ; GOSMANN, G. ; AVILA, R. R. P. D. ; HORN, M. A. . Acácia-Negra. Ciência Hoje , Rio de Janeiro, v. 11, n.63, p. 68-70, 1990.
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POSER, G. L. V. ; GOSMANN, G. . Produtos químicos vegetais como agentes defensivos. Scientia (Unisinos) , v. 1, n.1, p. 99-106, 1990.
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GOSMANN, G. ; SCHENKEL, Eloir Paulo ; SELIGMANN, O. . A new saponin from mate, Ilex paraguariensis. Journal of Natural Products , Chicago, v. 52, n.6, p. 1367-1370, 1989.
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SCHENKEL, E. P. ; GOSMANN, G. ; FARIAS, M. R. ; SANTOS, R. I. ; VIANNA, R. M. J. ; SIMOES, C. M. O. . O Controle de Qualidade de Insumos Vegetais e Fitoterapicos Na Faculdade de Farmacia da Ufrgs.. Caderno de Farmácia , v. 2, n.2, p. 139-151, 1986.